pyrroles has been researched along with Diarrhea in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (6.00) | 18.7374 |
| 1990's | 1 (2.00) | 18.2507 |
| 2000's | 7 (14.00) | 29.6817 |
| 2010's | 35 (70.00) | 24.3611 |
| 2020's | 4 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Deniz, OC; Erdamar, S; Gündoğdu, Y; Köksal, İ; Saka, D; Şişman, G | 1 |
| Doi, T; Honma, Y; Iwagami, S; Komatsu, Y; Kurokawa, Y; Naito, Y; Nishida, T; Sawaki, A; Takahashi, T | 1 |
| Chen, D; Gong, H; Han, D; Liu, C; Liu, S; Zhu, X | 1 |
| Bender, S; Boix, O; Cassier, PA; Cathomas, R; Cho, BC; Ellinghaus, P; Gajate, P; Grevel, J; Joerger, M; Navarro, A; Nogai, H; Nogova, L; Ocker, M; Park, SH; Penel, N; Rajagopalan, P; Richly, H; Sayehli, CM; Schostak, M; Schuler, M; Soo, RA; Tai, D | 1 |
| Fujioka, Y; Hashiguchi, K; Imamura, I; Kakiuchi, T; Kawakubo, H; Matsuo, M; Mizoe, A; Nakayama, A; Okuda, M; Yamaguchi, D; Yamamoto, K | 1 |
| Ambrose, H; Bando, H; Banerji, U; Barrett, JC; Baselga, J; Bedard, PL; Berger, MF; Bouvier, N; Chandarlapaty, S; Chang, MT; Dean, EJ; Donoghue, MTA; Dougherty, B; El-Khoueiry, AB; Erinjeri, JP; Foxley, A; Hyman, DM; Lindemann, JPO; McEwen, R; Mita, A; Pass, M; Pérez-Fidalgo, JA; Reichel, JB; Schellens, JHM; Schiavon, G; Selcuklu, SD; Smyth, LM; Solit, DB; Soumerai, TE; Taylor, BS; Torrisi, J; Westin, SN | 1 |
| Cai, W; Chen, YH; Dong, BJ; Huang, JW; Huang, YR; Kong, W; Li, MY; Xue, W; Yuan, YC; Zhang, J; Zhou, LX | 1 |
| Deleu, S; Hillewaert, V; Hoetelmans, RMW; Kakuda, TN; Leopold, L; Lwin, A; Spittaels, K; Vercauteren, JJ | 1 |
| Anderson, D; Finberg, RW; Fleischhackl, R; Kauffman, RS; Kosoglou, T; Lanno, R; Leopold, L; van Duijnhoven, W; Vingerhoets, J | 1 |
| Cil, O; Duan, T; Thiagarajah, JR; Verkman, AS | 1 |
| Cil, O; Donowitz, M; Duan, T; Lin, R; Sarker, R; Tse, CM; Verkman, AS | 1 |
| Armand, JP; Bahleda, R; Baselga, J; Berman, D; Calvo, E; Felip, E; Hanna, N; Harbison, CT; Herbst, RS; Kurland, JF; Laurie, SA; Park, JS; Pathak, AK; Shepherd, FA; Soria, JC; Vakkalagadda, B; Zhang, S | 1 |
| Devarakonda, S; Gopalan, PK; Govindan, R; Waqar, SN; Williams, K | 1 |
| Berardi, R; Burattini, L; Cascinu, S; Conti, A; De Giorgi, U; Iacovelli, R; Muzzonigro, G; Pantano, F; Santini, D; Santoni, M | 1 |
| Anders, RA; Deng, L; Fu, YX; Guo, X; Qiu, J; Tu, T; Yang, X; Zhou, L | 1 |
| Hashimoto, Y; Iizuka, J; Ikezawa, E; Kobayashi, H; Kondo, T; Nozaki, T; Omae, K; Takagi, T; Tanabe, K; Yoshida, K | 1 |
| Aieta, M; Amadori, D; Baldazzi, V; Basso, U; Burattini, L; Camerini, A; Chiuri, VE; De Giorgi, U; De Vincenzo, F; Ferrari, V; Fornarini, G; Lo Re, G; Luzi Fedeli, S; Masini, C; Moscetti, L; Rihawi, K; Rosti, G; Sava, T; Scarpi, E | 1 |
| Battista, K; Buckstein, R; Howson-Jan, K; Ivy, SP; Kovacs, MJ; Oza, AM; Schuh, AC; Storring, JM; Wang, ES; Wang, L; Wells, RA; Xenocostas, A; Yee, KW | 1 |
| Beuselinck, B; Claus, F; Cornelissen, L; De Keyzer, F; Dumez, H; Lerut, E; Van Poppel, H; Wolter, P | 1 |
| Basso, U; Bonetti, A; Bracarda, S; Calabrò, F; Capaccetti, B; Cartenì, G; Ciuffreda, L; Fea, E; Ferrari, V; Fly, K; Gasparini, G; Gasparro, D; Hariharan, S; Labianca, R; Lo Re, G; Masini, C; Porta, C; Ruggeri, EM; Sternberg, CN; Tassinari, D; Zhang, K | 1 |
| Biasco, G; Chen, L; Demetri, GD; Fly, K; Fumagalli, E; Gelderblom, H; Hurwitz, HI; Kaiser, PE; Kang, YK; Lechuga, MJ; Matczak, E; Reichardt, P; Rosen, LS; Rutkowski, P; Schuette, J; Seddon, B; Williams, CC; Yalcin, S | 1 |
| Kulke, MH | 1 |
| Bailey, DB; Borgatti, A; Clifford, CA; Crawford-Jakubiak, M; Cronin, KL; Gardner, HL; Gill, VL; Henry, CJ; Klein, MK; Locke, J; London, CA; Mathie, T; Northrup, NC; Pennell, ML; Phillips, B; Portela, R; Post, G; Rosenberg, MP; Ruslander, DM; Stingle, N; Thamm, DH; Vail, DM; Williams, LE; Wilson-Robles, H | 1 |
| Charles, LP; DeAnnuntis, L; Escudier, B; Gore, ME; Hariharan, S; Motzer, RJ; Porta, C; Rini, BI; Yang, L | 1 |
| Albiges, L; Choueiri, TK; De Velasco, G; Fay, AP; Heng, DY; Kaymakcalan, MD; Kollmannsberger, CK; Kroeger, N; Lee, JL; McKay, RR; North, SA; Rha, SY; Smoragiewicz, M; Wells, JC; Xie, W | 1 |
| Barett, C; Bikas, A; Burman, KD; Clark, BG; Desale, S; Gandhi, R; Jelinek, JS; Kundra, P; Mete, M; O'Keefe, K; Wartofsky, L; Wexler, JA; Wray, L | 1 |
| Chi, Z; Cui, C; Guo, J; Li, S; Lian, B; Mao, L; Sheng, X; Si, L; Tang, B; Wang, X; Yan, X | 1 |
| Blumenstengel, K; Busies, S; Hutzschenreuter, U; Marschner, N; Müller, L; Münch, A | 1 |
| Boers-Sonderen, MJ; Derikx, LA; Hoentjen, F; Mulder, SF; Mulders, PF; Nagtegaal, ID; van der Graaf, WT; van Herpen, CM; Wanten, GJ | 1 |
| Cil, O; Donowitz, M; Gillespie, AM; Lee, S; Lin, R; Phuan, PW; Tradtrantip, L; Tse, M; Verkman, AS; Yin, J; Zachos, NC | 1 |
| Beniak, J; Kakalejcik, M; Reckova, M | 1 |
| Andrieu, JM; Azizi, M; Banu, E; Chedid, A; Fournier, L; Helley, D; Medioni, J; Mejean, A; Oudard, S; Scotte, F | 1 |
| Dubertret, L; Gressier, L; Pruvost-Balland, C; Viguier, M | 1 |
| Curiel, RE; Motzer, RJ; Patel, PH; Senico, PL | 1 |
| Bergman, PJ; Boucher, JF; Couto, GC; Henry, CJ; Hintermeister, JG; Klein, MK; London, CA; Malpas, PB; Mauldin, GN; Michels, GM; Mitchener, KL; Rosenberg, MP; Rusk, AW; Wood-Follis, SL | 1 |
| Wood, LS | 1 |
| Díaz-Rubio, E; López-Tarruella, S; Manzano, A; Martin, M; Puente, J | 1 |
| Grünwald, V; Kalanovic, D; Merseburger, AS | 1 |
| Bello, A; Burris, HA; Chao, R; Chiorean, EG; Jones, S; Lee, FC; Liau, KF; Royce, M; Sweeney, CJ; Tye, L; Verschraegen, CF | 1 |
| Bjarnason, G; Bukowski, R; Burnett, P; Creel, P; Davis, M; Dawson, N; Feldman, D; George, S; Hershman, J; Kollmannsberger, C; Lechner, T; Potter, A; Raymond, E; Treister, N; Wood, L; Wu, S | 1 |
| Greil, R; Grundbichler, M; Kappacher, A; Mlineritsch, B; Moik, M; Ressler, S; Rosenlechner, S | 1 |
| Antón-Aparicio, LM; Cassinello, J; Castellano, D; Esteban, E; González-Larriba, JL; Grande, E; Sepúlveda, J | 1 |
| He, H; Shen, Z; Wang, H; Wang, X; Wu, Y; Zhang, C; Zhao, J; Zhou, W; Zhu, Y | 1 |
| Brickman, MJ; Citrin, DL; Dees, EC; Healey, P; Kern, KA; Li, S; Myers, SD; Paolini, J; Wang, Z; Yardley, DA | 1 |
| Bondarenko, I; Carrato, A; Christensen, JG; De la Cruz, JA; Jonker, DJ; Korytowsky, B; Lechuga, MJ; Lim, R; Lin, X; Roman, L; Shparyk, Y; Staszewska-Skurczynska, M; Sun, Y; Swieboda-Sadlej, A; Tursi, JM; Van Cutsem, E; Williams, JA | 1 |
| Ballantyne, CM; Blazing, MA; Davidson, MH; DeLucca, P; Hunninghake, DB; Hustad, CM; Palmisano, J; Ramsey, KE; Yuan, Z | 1 |
| Burdisso, M; Leali, M; Panzone, G; Schiatti, P; Selva, D; Tarzia, G | 1 |
| Arletti, R; Benelli, A; Bertolini, A; Cavazzuti, E; Poggioli, R | 1 |
| Beattie, DE; Dover, GM; Ward, TJ | 1 |
| Allen, JR; Hsu, IC | 1 |
5 review(s) available for pyrroles and Diarrhea
| Article | Year |
|---|---|
Adverse events of vonoprazan in the treatments of acid-related diseases: a systematic review and meta-analysis.
Topics: Constipation; Diarrhea; Humans; Proton Pump Inhibitors; Pyrroles; Sulfonamides | 2023 |
Risk of gastrointestinal events with sorafenib, sunitinib and pazopanib in patients with solid tumors: a systematic review and meta-analysis of clinical trials.
Topics: Adverse Drug Reaction Reporting Systems; Carcinoma, Renal Cell; Clinical Trials as Topic; Diarrhea; Gastrointestinal Diseases; Gastrointestinal Tract; Humans; Incidence; Indazoles; Indoles; Liver Neoplasms; Neoplasms; Niacinamide; Phenylurea Compounds; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Sunitinib; Vomiting | 2014 |
Management of vascular endothelial growth factor and multikinase inhibitor side effects.
Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Diarrhea; Drug Eruptions; Drug Monitoring; Fatigue; Humans; Indoles; Interleukin-2; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Male; Niacinamide; Oncology Nursing; Phenylurea Compounds; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Sorafenib; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A | 2009 |
Management of sunitinib-related adverse events: an evidence- and expert-based consensus approach.
Topics: Carcinoma, Renal Cell; Consensus; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Early Detection of Cancer; Evidence-Based Medicine; Fatigue; Female; Follow-Up Studies; Humans; Hypertension; Indoles; Kidney Neoplasms; Male; Mouth Diseases; Practice Guidelines as Topic; Protein Kinase Inhibitors; Pyrroles; Risk Assessment; Skin Diseases; Sunitinib; Treatment Outcome | 2010 |
Sunitinib in metastatic renal cell carcinoma: recommendations for management of noncardiovascular toxicities.
Topics: Asthenia; Carcinoma, Renal Cell; Diarrhea; Dose-Response Relationship, Drug; Erythema; Exanthema; Fatigue; Humans; Hypothyroidism; Indoles; Kidney Neoplasms; Practice Guidelines as Topic; Protein Kinase Inhibitors; Pyrroles; Standard of Care; Sunitinib | 2011 |
19 trial(s) available for pyrroles and Diarrhea
| Article | Year |
|---|---|
Pimitespib in patients with advanced gastrointestinal stromal tumor (CHAPTER-GIST-301): a randomized, double-blind, placebo-controlled phase III trial.
Topics: Antineoplastic Agents; Diarrhea; Double-Blind Method; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Pyrroles | 2022 |
Rogaratinib in patients with advanced cancers selected by FGFR mRNA expression: a phase 1 dose-escalation and dose-expansion study.
Topics: Acute Kidney Injury; Aged; Anorexia; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Carcinoma, Transitional Cell; Diarrhea; Fatigue; Female; Humans; Hyperphosphatemia; Hypoglycemia; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Piperazines; Pyrroles; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Fibroblast Growth Factor, Type 2; Receptor, Fibroblast Growth Factor, Type 3; Receptors, Fibroblast Growth Factor; RNA, Messenger; Squamous Cell Carcinoma of Head and Neck; Thiophenes; Vomiting | 2019 |
Effect of probiotics during vonoprazan-containing triple therapy on gut microbiota in Helicobacter pylori infection: A randomized controlled trial.
Topics: Adolescent; Amoxicillin; Anti-Bacterial Agents; Clarithromycin; Diarrhea; Drug Therapy, Combination; Female; Gastrointestinal Microbiome; Helicobacter Infections; Helicobacter pylori; Humans; Male; Probiotics; Pyrroles; Sulfonamides | 2020 |
Single- and multiple-dose pharmacokinetics and safety of pimodivir, a novel, non-nucleoside polymerase basic protein 2 subunit inhibitor of the influenza A virus polymerase complex, and interaction with oseltamivir: a Phase 1 open-label study in healthy v
Topics: Adolescent; Adult; Antiviral Agents; Area Under Curve; Cross-Over Studies; Diarrhea; Double-Blind Method; Drug Interactions; Female; Humans; Male; Middle Aged; Oseltamivir; Pyridines; Pyrimidines; Pyrroles; Time Factors; Young Adult | 2018 |
Phase 2b Study of Pimodivir (JNJ-63623872) as Monotherapy or in Combination With Oseltamivir for Treatment of Acute Uncomplicated Seasonal Influenza A: TOPAZ Trial.
Topics: Acute Disease; Adult; Antiviral Agents; Diarrhea; Double-Blind Method; Drug Resistance, Viral; Drug Therapy, Combination; Early Termination of Clinical Trials; Female; Humans; Influenza A virus; Influenza, Human; Male; Middle Aged; Oseltamivir; Pyridines; Pyrimidines; Pyrroles; Time Factors; Viral Load; Viral Proteins; Virus Shedding | 2019 |
Phase I-IIa study of BMS-690514, an EGFR, HER-2 and -4 and VEGFR-1 to -3 oral tyrosine kinase inhibitor, in patients with advanced or metastatic solid tumours.
Topics: Administration, Oral; Adult; Aged; Area Under Curve; Carcinoma, Non-Small-Cell Lung; Diarrhea; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; ErbB Receptors; Erlotinib Hydrochloride; Exanthema; Female; Humans; Lung Neoplasms; Male; Metabolic Clearance Rate; Middle Aged; Neoplasm Metastasis; Neoplasms; Piperidines; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Receptor, ErbB-2; Treatment Outcome; Triazines; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-3 | 2013 |
A phase I trial of sunitinib and rapamycin in patients with advanced non-small cell lung cancer.
Topics: Administration, Oral; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Cohort Studies; Diarrhea; Drug Administration Schedule; Female; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pyrroles; Sirolimus; Sunitinib; Treatment Outcome | 2013 |
Sunitinib malate in patients with intermediate-2 or high-risk myelodysplastic syndrome or chronic myelomonocytic leukemia.
Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Diarrhea; Drug Administration Schedule; Fatigue; Female; Humans; Indoles; Kaplan-Meier Estimate; Leukemia, Myelomonocytic, Chronic; Male; Middle Aged; Myelodysplastic Syndromes; Pyrroles; Remission Induction; Sunitinib; Thrombocytopenia; Treatment Outcome | 2014 |
Safety and efficacy of sunitinib in patients from Italy with metastatic renal cell carcinoma: final results from an expanded-access trial.
Topics: Adult; Aged; Anemia; Antineoplastic Agents; Asthenia; Carcinoma, Renal Cell; Compassionate Use Trials; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Dysgeusia; Female; Follow-Up Studies; Humans; Hypertension; Incidence; Indoles; Italy; Kaplan-Meier Estimate; Kidney Neoplasms; Leukopenia; Male; Middle Aged; Neutropenia; Pyrroles; Stomatitis; Sunitinib; Thrombocytopenia; Treatment Outcome | 2015 |
Clinical outcomes of patients with advanced gastrointestinal stromal tumors: safety and efficacy in a worldwide treatment-use trial of sunitinib.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Child; Diarrhea; Disease-Free Survival; Fatigue; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Proportional Hazards Models; Pyrroles; Sarcoma; Sunitinib; Treatment Outcome; Young Adult | 2015 |
Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study.
Topics: Administration, Metronomic; Amputation, Surgical; Animals; Bone Neoplasms; Carboplatin; Cyclophosphamide; Diarrhea; Disease-Free Survival; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Indoles; Kaplan-Meier Estimate; Male; Neutropenia; Osteosarcoma; Piroxicam; Prospective Studies; Pyrroles; Regression Analysis; Treatment Outcome | 2015 |
Phase 2 clinical trial of sunitinib as adjunctive treatment in patients with advanced differentiated thyroid cancer.
Topics: Adenocarcinoma, Follicular; Adenoma, Oxyphilic; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Bone Neoplasms; Carcinoma; Carcinoma, Papillary; Chemotherapy, Adjuvant; Diarrhea; Disease-Free Survival; Fatigue; Female; Hand-Foot Syndrome; Humans; Indoles; Iodine Radioisotopes; Leukopenia; Lung Neoplasms; Male; Middle Aged; Nausea; Pyrroles; Radiotherapy; Sunitinib; Thyroid Cancer, Papillary; Thyroid Neoplasms | 2016 |
Phase I study combining treatment with temsirolimus and sunitinib malate in patients with advanced renal cell carcinoma.
Topics: Administration, Oral; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Cellulitis; Diarrhea; Drug Eruptions; Female; Humans; Indoles; Infusions, Intravenous; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Sirolimus; Stomatitis; Sunitinib; Thrombocytopenia; Treatment Outcome | 2009 |
A phase I study of sunitinib plus capecitabine in patients with advanced solid tumors.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Capecitabine; Deoxycytidine; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Indoles; Male; Metabolic Clearance Rate; Middle Aged; Nausea; Neoplasms; Pyrroles; Sunitinib; Treatment Outcome; Vomiting; Young Adult | 2010 |
Experience in the use of sunitinib given as a single agent in metastatic chemoresistant and castration-resistant prostate cancer patients.
Topics: Adenocarcinoma; Aged; Aged, 80 and over; Anemia; Angiogenesis Inhibitors; Castration; Diarrhea; Drug Resistance, Neoplasm; Fatigue; Hand-Foot Syndrome; Humans; Indoles; Male; Middle Aged; Prostate-Specific Antigen; Prostatic Neoplasms; Pyrroles; Sunitinib; Thrombocytopenia; Treatment Outcome | 2011 |
Sorafenib or sunitinib as postoperative adjuvant therapy for Chinese patients with locally advanced clear cell renal cell carcinoma at high risk for disease recurrence.
Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Diarrhea; Disease-Free Survival; Fatigue; Female; Follow-Up Studies; Hand-Foot Syndrome; Humans; Indoles; Kidney; Kidney Neoplasms; Male; Middle Aged; Neoplasm Recurrence, Local; Niacinamide; Phenylurea Compounds; Postoperative Period; Prospective Studies; Pyrroles; Risk Factors; Sorafenib; Sunitinib; Treatment Outcome | 2013 |
Phase II open-label study of sunitinib in patients with advanced breast cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Breast Neoplasms; Diarrhea; Disease-Free Survival; Fatigue; Female; Humans; Indoles; Middle Aged; Nausea; Pyrroles; Sunitinib; Thrombocytopenia; Treatment Outcome | 2012 |
Fluorouracil, leucovorin, and irinotecan plus either sunitinib or placebo in metastatic colorectal cancer: a randomized, phase III trial.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Diarrhea; Double-Blind Method; Drug Administration Schedule; Fatigue; Female; Fluorouracil; Humans; Indoles; Irinotecan; Kaplan-Meier Estimate; Leucovorin; Male; Middle Aged; Neoplasm Metastasis; Neutropenia; Pyrroles; Sunitinib; Thrombocytopenia; Treatment Outcome | 2013 |
Effect on high-density lipoprotein cholesterol of maximum dose simvastatin and atorvastatin in patients with hypercholesterolemia: results of the Comparative HDL Efficacy and Safety Study (CHESS).
Topics: Adult; Aged; Alkaline Phosphatase; Apolipoprotein A-I; Atorvastatin; Cholesterol, HDL; Diarrhea; Double-Blind Method; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Musculoskeletal Diseases; Nausea; Pyrroles; Simvastatin | 2003 |
26 other study(ies) available for pyrroles and Diarrhea
| Article | Year |
|---|---|
Sunitinib induced colitis manifesting as invasive diarrhea in a patient with renal cell carcinoma.
Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Colitis; Diarrhea; Humans; Indoles; Kidney Neoplasms; Pyrroles; Sunitinib | 2022 |
AKT Inhibition in Solid Tumors With AKT1 Mutations.
Topics: Adult; Aged; Alleles; Antineoplastic Agents; Biomarkers, Tumor; Diarrhea; Disease-Free Survival; DNA, Neoplasm; Drug Eruptions; Exanthema; Female; Humans; Hyperglycemia; Loss of Heterozygosity; Male; Middle Aged; Mutation; Neoplasms; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Response Evaluation Criteria in Solid Tumors; Signal Transduction | 2017 |
[Comparison of efficacy between sorafenib and sunitinib as first-line therapy for metastatic renal cell carcinoma and analyze prognostic factors for survival].
Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Diarrhea; Disease Progression; Disease-Free Survival; Hand-Foot Syndrome; Humans; Indoles; Kidney Neoplasms; Multivariate Analysis; Neutropenia; Niacinamide; Phenylurea Compounds; Prognosis; Proportional Hazards Models; Pyrroles; Retrospective Studies; Risk Factors; Sorafenib; Sunitinib; Thrombocytopenia; Treatment Outcome | 2018 |
Intestinal epithelial potassium channels and CFTR chloride channels activated in ErbB tyrosine kinase inhibitor diarrhea.
Topics: Acetamides; Afatinib; Animals; Cell Membrane Permeability; Clotrimazole; Colon; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Disease Models, Animal; Epithelial Cells; ErbB Receptors; Female; Humans; Intestinal Mucosa; Neoplasms; Oxazines; Potassium Channel Blockers; Potassium Channels; Protein Kinase Inhibitors; Pyrimidinones; Pyrroles; Rats; Trityl Compounds | 2019 |
Inhibition of CFTR-mediated intestinal chloride secretion as potential therapy for bile acid diarrhea.
Topics: Animals; Cell Line; Cells, Cultured; Chenodeoxycholic Acid; Chlorides; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Female; Humans; Intestinal Mucosa; Intestinal Secretions; Mice; Oxazines; Pyrimidinones; Pyrroles; Rats; Rats, Sprague-Dawley | 2019 |
Induction of innate lymphoid cell-derived interleukin-22 by the transcription factor STAT3 mediates protection against intestinal infection.
Topics: Animals; Cells, Cultured; Citrobacter rodentium; Diarrhea; Enterobacteriaceae Infections; Humans; Immunity, Innate; Indoles; Interleukin-17; Interleukin-22; Interleukins; Intestines; Lymphocytes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Transgenic; Mucous Membrane; Nuclear Receptor Subfamily 1, Group F, Member 3; Pyrroles; STAT3 Transcription Factor; Sunitinib; T-Lymphocytes, Helper-Inducer | 2014 |
Superior tolerability of altered dosing schedule of sunitinib with 2-weeks-on and 1-week-off in patients with metastatic renal cell carcinoma--comparison to standard dosing schedule of 4-weeks-on and 2-weeks-off.
Topics: Adult; Aged; Angiogenesis Inhibitors; Carcinoma, Renal Cell; Diarrhea; Disease-Free Survival; Drug Administration Schedule; Female; Hand-Foot Syndrome; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Staging; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome | 2014 |
Lymphopenia and clinical outcome of elderly patients treated with sunitinib for metastatic renal cell cancer.
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Carcinoma, Renal Cell; Diarrhea; Female; Follow-Up Studies; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Lymphopenia; Male; Neoplasm Staging; Neutropenia; Prognosis; Pyrroles; Risk Factors; Sunitinib; Treatment Outcome | 2014 |
Incidence of bowel wall oedema on computed tomography exams and association with diarrhoea in renal cell carcinoma patients treated with sunitinib.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Belgium; Carcinoma, Renal Cell; Diarrhea; Edema; Female; Follow-Up Studies; Humans; Incidence; Indoles; Intestines; Kidney Neoplasms; Male; Middle Aged; Multidetector Computed Tomography; Pyrroles; Retrospective Studies; Sunitinib | 2015 |
Sequencing and combining systemic therapies for pancreatic neuroendocrine tumors.
Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers, Tumor; Diarrhea; Drug Administration Schedule; Everolimus; Humans; Indoles; Ki-67 Antigen; Liver Neoplasms; Male; Middle Aged; Mitotic Index; Neoplasm Grading; Neuroendocrine Tumors; Pancreatic Neoplasms; Pyrroles; Sirolimus; Somatostatin; Sunitinib; Tomography, X-Ray Computed | 2015 |
Long-term Safety of Sunitinib in Metastatic Renal Cell Carcinoma.
Topics: Anorexia; Antineoplastic Agents; Carcinoma, Renal Cell; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diarrhea; Dysgeusia; Dyspepsia; Fatigue; Female; Humans; Hypertension; Hypothyroidism; Indoles; Kidney Neoplasms; Male; Mucositis; Nausea; Pyrroles; Stomatitis; Sunitinib; Time Factors | 2016 |
Risk factors and model for predicting toxicity-related treatment discontinuation in patients with metastatic renal cell carcinoma treated with vascular endothelial growth factor-targeted therapy: Results from the International Metastatic Renal Cell Carcin
Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Axitinib; Bevacizumab; Carcinoma, Renal Cell; Databases, Factual; Diarrhea; Drug Administration Schedule; Fatigue; Female; Hand-Foot Syndrome; Humans; Imidazoles; Indazoles; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Male; Middle Aged; Models, Statistical; Molecular Targeted Therapy; Mucositis; Niacinamide; Phenylurea Compounds; Predictive Value of Tests; Pyrimidines; Pyrroles; Retrospective Studies; Risk Assessment; Risk Factors; Sorafenib; Sulfonamides; Sunitinib; Vascular Endothelial Growth Factor A | 2016 |
Efficacy and safety of sorafenib versus sunitinib as first-line treatment in patients with metastatic renal cell carcinoma: largest single-center retrospective analysis.
Topics: Antineoplastic Agents; Carcinoma, Renal Cell; Diarrhea; Disease-Free Survival; Fatigue; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome | 2016 |
Adverse reactions in mRCC patients documented in routine practice by German office-based oncologists and uro-oncologists.
Topics: Aged; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Renal Cell; Diarrhea; Documentation; Fatigue; Female; Germany; Humans; Indoles; Interferons; Kidney Neoplasms; Male; Medical Oncology; Middle Aged; Nausea; Niacinamide; Phenylurea Compounds; Prospective Studies; Pyrroles; Registries; Sirolimus; Sorafenib; Stomatitis; Sunitinib | 2017 |
Endoscopy in patients with diarrhea during treatment with vascular endothelial growth factor receptor tyrosine kinase inhibitors: Is the cause in the mucosa?
Topics: Aged; Antineoplastic Agents; Capsule Endoscopy; Carcinoma, Renal Cell; Diarrhea; Endoscopy, Gastrointestinal; Female; Humans; Indoles; Intestinal Mucosa; Kidney Neoplasms; Male; Middle Aged; Protein Kinase Inhibitors; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sunitinib | 2016 |
Benzopyrimido-pyrrolo-oxazine-dione CFTR inhibitor (R)-BPO-27 for antisecretory therapy of diarrheas caused by bacterial enterotoxins.
Topics: Animals; Cystic Fibrosis Transmembrane Conductance Regulator; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Intestines; Mice; Molecular Structure; Oxazines; Pyrimidinones; Pyrroles | 2017 |
Treatment of hemodialyzed patient with sunitinib.
Topics: Anemia; Antineoplastic Agents; Carcinoma, Renal Cell; Coronary Artery Bypass; Diarrhea; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hypertension; Indoles; Male; Middle Aged; Nausea; Nephrectomy; Pyrroles; Remission Induction; Renal Dialysis; Sunitinib; Thrombocytopenia; Treatment Outcome; Vomiting | 2009 |
Salvage therapy with bevacizumab-sunitinib combination after failure of sunitinib alone for metastatic renal cell carcinoma: a case series.
Topics: Anorexia; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Asthenia; Bevacizumab; Bone Neoplasms; Carcinoma, Renal Cell; Diarrhea; Disease Progression; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Mucositis; Pancreatic Neoplasms; Pyrroles; Salvage Therapy; Sunitinib | 2009 |
[Atorvastatin-induced drug reaction with eosinophilia and systemic symptoms (DRESS)].
Topics: Abdominal Pain; Arthralgia; Atorvastatin; Diarrhea; Drug Eruptions; Eosinophilia; Facial Dermatoses; Female; Fever; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Middle Aged; Pyrroles | 2009 |
Multi-center, placebo-controlled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision.
Topics: Animals; Anorexia; Diarrhea; Disease Progression; Dog Diseases; Dogs; Female; Indoles; Male; Mast-Cell Sarcoma; Neoplasm Recurrence, Local; Pyrroles; Random Allocation; Receptor Protein-Tyrosine Kinases; Treatment Outcome; Vomiting | 2009 |
Breast cancer: complete response with the combination of sunitinib and trastuzumab in a patient with grade III ductal carcinoma.
Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Carcinoma, Ductal, Breast; Diarrhea; Female; Heart Function Tests; Humans; Hypothyroidism; Indoles; Lymphatic Metastasis; Middle Aged; Paclitaxel; Pyrroles; Remission Induction; Sunitinib; Trastuzumab | 2010 |
Efficacy of temsirolimus after previous treatment with sunitinib, sorafenib or everolimus in advanced renal cell cancer.
Topics: Aged; Aged, 80 and over; Anemia; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Carcinoma, Renal Cell; Diarrhea; Disease-Free Survival; Everolimus; Female; Humans; Indoles; Karnofsky Performance Status; Kidney Neoplasms; Lymphatic Metastasis; Male; Middle Aged; Nausea; Neoplasm Metastasis; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies; Sirolimus; Sorafenib; Sunitinib; Thrombocytopenia | 2011 |
Synthesis and pharmacological evaluation of a series of analgesic and antiinflammatory 4-aminopyrroles.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arachidonic Acid; Arachidonic Acids; Arthritis, Experimental; Carrageenan; Chemical Phenomena; Chemistry; Diarrhea; Edema; Lethal Dose 50; Male; Pyrroles; Rats; Rats, Inbred Strains; Structure-Activity Relationship; Ulcer | 1984 |
K+ channel openers delay intestinal transit and have antidiarrheal activity.
Topics: Animals; Benzopyrans; Cromakalim; Diarrhea; Dose-Response Relationship, Drug; Gastrointestinal Motility; Guanidines; Male; Mice; Mice, Inbred Strains; Morphine; Pinacidil; Potassium Channels; Pyrroles; Vasodilator Agents | 1995 |
Synthesis and antidiarrheal activity of N-(aminoiminomethyl)-1H-pyrrole-1-acetamides related to guanfacine.
Topics: Animals; Cardiovascular System; Castor Oil; Chemical Phenomena; Chemistry; Diarrhea; Female; Guanfacine; Guanidines; Male; Phenylacetates; Pyrroles; Rats; Stereoisomerism; Structure-Activity Relationship | 1985 |
Antimitotic effects of dehydroretronecine pyrrole.
Topics: Animals; Blood Proteins; Body Weight; Diarrhea; Gastric Mucosa; Gastrointestinal Hemorrhage; Hemoglobins; Leukocyte Count; Male; Methanol; Mitosis; Pyrroles; Pyrrolizidine Alkaloids; Rats; Remission, Spontaneous; Serum Albumin; Serum Globulins; Spleen; Stomach Ulcer; Thymus Gland | 1974 |