pyrroles has been researched along with Chronic Insomnia in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Beneš, H; De Boer, P; Dorffner, G; Drevets, WC; Jahn, H; Keicher, C; Kent, JM; Kezic, I; Luthringer, R; Parapatics, S; Rofael, H; Seiden, DJ; van der Ark, P; van Gerven, J | 1 |
| Brooks, S; de Boer, P; Drevets, W; Jacobs, GE; Kent, JM; Kezic, I; Luthringer, R; van Amerongen, G; van der Ark, P; van Gerven, JM; Van Nueten, L; Zuiker, R | 1 |
| Bonaventure, P; Carruthers, NI; Dugovic, C; Koudriakova, T; Letavic, MA; Lord, B; Lovenberg, TW; Ly, KS; Mani, NS; Nepomuceno, D; Pippel, DJ; Rizzolio, M; Shah, CR; Shelton, JE; Shireman, BT; Young, LK; Yun, S | 1 |
| Cao, C; Chen, S; Chen, Y; He, H; Hou, L; Hu, Y; Lan, J; Li, J; Li, Y; Liang, W; Liu, X; Luo, Z; Lv, Q; Shen, L; Shi, W; Sun, Y; Wang, Y; Wu, S; Xu, Q; Zhang, H | 1 |
2 trial(s) available for pyrroles and Chronic Insomnia
| Article | Year |
|---|---|
A randomized Phase 2 study to evaluate the orexin-2 receptor antagonist seltorexant in individuals with insomnia without psychiatric comorbidity.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Headache; Humans; Male; Middle Aged; Orexin Receptor Antagonists; Orexin Receptors; Polysomnography; Pyrimidines; Pyrroles; Sleep; Sleep Initiation and Maintenance Disorders; Sleepiness; Surveys and Questionnaires; Time Factors; Treatment Outcome; Triazoles; Young Adult | 2018 |
The selective orexin-2 receptor antagonist seltorexant improves sleep: An exploratory double-blind, placebo controlled, crossover study in antidepressant-treated major depressive disorder patients with persistent insomnia.
Topics: Adult; Aged; Antidepressive Agents; Cross-Over Studies; Depressive Disorder, Major; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Male; Middle Aged; Orexin Receptor Antagonists; Polysomnography; Pyrimidines; Pyrroles; Sleep Initiation and Maintenance Disorders; Treatment Outcome; Triazoles; Young Adult | 2019 |
2 other study(ies) available for pyrroles and Chronic Insomnia
| Article | Year |
|---|---|
Novel Octahydropyrrolo[3,4-c]pyrroles Are Selective Orexin-2 Antagonists: SAR Leading to a Clinical Candidate.
Topics: Animals; Clinical Trials as Topic; Dogs; Humans; Intracellular Signaling Peptides and Proteins; Male; Neuropeptides; Orexin Receptors; Orexins; Pyrroles; Rats; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship; Substrate Specificity | 2015 |
Discovery of novel substituted octahydropyrrolo[3,4-c]pyrroles as dual orexin receptor antagonists for insomnia treatment.
Topics: Animals; Drug Discovery; Electroencephalography; Humans; Male; Orexin Receptor Antagonists; Pyrroles; Rats; Rats, Sprague-Dawley; Sleep Initiation and Maintenance Disorders; Structure-Activity Relationship | 2017 |