Page last updated: 2024-08-18

pyrroles and Cerebral Hemorrhage

pyrroles has been researched along with Cerebral Hemorrhage in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (53.85)29.6817
2010's11 (42.31)24.3611
2020's1 (3.85)2.80

Authors

AuthorsStudies
Gao, X; Han, Z; Lei, P; Li, M; Li, X; Liu, M; Liu, Q; Zhang, W1
Chen, D; Shen, J; Tan, T; Tu, L; Wang, S; Wang, Y1
Ducruet, AF; Lawton, MT; Qiu, S; Sheth, KN; Shi, E; Shi, K1
Hou, T; Lee, SM; Li, P; Li, S; Li, Y; Pan, P; Shen, M; Yu, H; Zhang, L; Zhou, S1
Chen, Z; Gao, F; Hua, Y; Keep, RF; Liu, F; Xi, G1
Hou, T; Lee, SM; Li, C; Li, D; Li, Y; Pan, P; Shen, M; Sun, H; Tian, S; Zhou, H1
Chen, Q; Deng, G; Li, M; Li, Q; Wan, J; Wang, J; Wang, W; Wang, Y; Yang, Q1
Jin, WN; Li, M; Li, Z; Liu, Q; Ren, H; Sheth, KN; Shi, FD; Wood, K1
Fitchett, DH; Goodman, SG; Langer, A1
Amarenco, P; Callahan, A; Goldstein, LB; Hennerici, MG; Messig, M; Sillesen, H; Welch, KM; Zivin, J1
Amarenco, P; Benavente, O; Callahan, A; Gilbert, S; Goldstein, LB; Hennerici, MG; Rudolph, AE; Sillesen, H; Simunovic, L; Welch, KM; Zivin, JA1
Goldstein, MR; Mascitelli, L; Pezzetta, F1
El-Remessy, AB; Elewa, HF; Ergul, A; Fagan, SC; Frye, RF; Johnson, MH; Kozak, A1
Chaturvedi, S; Goldstein, MR; Mascitelli, L; Pezzetta, F1
Chopp, M; Han, Y; Karki, K; Knight, RA; Ledbetter, KA; Seyfried, DM; Yang, D; Zhang, J1
Chopp, M; Ding, C; Han, Y; Karki, K; Knight, RA; Seyfried, DM; Yang, D; Zhang, J1
Cui, JJ; Gao, F; Li, YR; Wang, D1
Chaogang, T; Ewen, T; Guanghong, X; Jun, W; Liming, T; Qiuting, L; Tao, T1
Eisa-Beygi, S; Ekker, M; Hatch, G; Moon, TW; Noble, S1
Alexy, T; Czopf, J; Habon, T; Horvath, B; Juricskay, I; Kesmarky, G; Koltai, K; Marton, Z; Szapary, L; Szots, M; Toth, K1
Chu, K; Han, SY; Jeong, SW; Jung, KH; Kim, JY; Kim, M; Lee, ST; Roh, JK1
Bydon, A; Chen, J; Chopp, M; Han, Y; Lu, D; Seyfried, D1
Amarenco, P; Bogousslavsky, J; Callahan, A; Goldstein, LB; Hennerici, M; Rudolph, AE; Sillesen, H; Simunovic, L; Szarek, M; Welch, KM; Zivin, JA1
Cohen, JS1
Culine, S; Pouessel, D1
Karam, JG; Loney-Hutchinson, L; McFarlane, SI1

Trials

2 trial(s) available for pyrroles and Cerebral Hemorrhage

ArticleYear
Results of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial by stroke subtypes.
    Stroke, 2009, Volume: 40, Issue:4

    Topics: Anticholesteremic Agents; Atorvastatin; Brain Ischemia; Cerebral Hemorrhage; Female; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Middle Aged; Placebos; Proportional Hazards Models; Pyrroles; Risk Factors; Stroke; Treatment Outcome

2009
High-dose atorvastatin after stroke or transient ischemic attack.
    The New England journal of medicine, 2006, 08-10, Volume: 355, Issue:6

    Topics: Adult; Atorvastatin; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebral Infarction; Cholesterol, LDL; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Attack, Transient; Male; Proportional Hazards Models; Pyrroles; Risk; Secondary Prevention; Stroke

2006

Other Studies

24 other study(ies) available for pyrroles and Cerebral Hemorrhage

ArticleYear
Microglial replacement in the aged brain restricts neuroinflammation following intracerebral hemorrhage.
    Cell death & disease, 2022, 01-10, Volume: 13, Issue:1

    Topics: Aging; Aminopyridines; Animals; Blood-Brain Barrier; Brain; Brain Injuries; Cell Death; Cerebral Hemorrhage; Chemotaxis, Leukocyte; Disease Models, Animal; Mice; Microglia; Neuroinflammatory Diseases; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor

2022
TRPV4 channels stimulate Ca
    Brain research bulletin, 2019, Volume: 146

    Topics: Animals; Apoptosis; Brain Injuries; Calcium; Cell Death; Cell Survival; Cerebral Hemorrhage; Endoplasmic Reticulum Stress; Inositol 1,4,5-Trisphosphate Receptors; Leucine; Male; Mice; Mice, Inbred C57BL; Morpholines; Neurons; Pyrroles; Sulfonamides; TRPV Cation Channels; Unfolded Protein Response

2019
Chronic inflammation, cognitive impairment, and distal brain region alteration following intracerebral hemorrhage.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019, Volume: 33, Issue:8

    Topics: Aminopyridines; Animals; Brain; Cerebral Hemorrhage; Cognition; Cognitive Dysfunction; Disease Models, Animal; Fingolimod Hydrochloride; Flow Cytometry; Hippocampus; Inflammation; Male; Mice; Mice, Inbred C57BL; Microglia; Neuroimaging; Neuronal Plasticity; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor

2019
Discovery of Rho-kinase inhibitors by docking-based virtual screening.
    Molecular bioSystems, 2013, Volume: 9, Issue:6

    Topics: Animals; Antineoplastic Agents; Atorvastatin; Breast Neoplasms; Cell Line, Tumor; Cerebral Hemorrhage; Drug Evaluation, Preclinical; Drug Screening Assays, Antitumor; Female; HeLa Cells; Heptanoic Acids; Humans; Lung Neoplasms; Models, Molecular; Molecular Docking Simulation; Molecular Dynamics Simulation; Molecular Structure; Multiple Myeloma; Protein Kinase Inhibitors; Pyrroles; rho-Associated Kinases; Zebrafish

2013
Hydrocephalus after intraventricular hemorrhage: the role of thrombin.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2014, Volume: 34, Issue:3

    Topics: Animals; Blood-Brain Barrier; Cerebral Hemorrhage; Cerebral Ventricles; Hydrocephalus; Injections, Intraventricular; Magnetic Resonance Imaging; Male; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Thrombin

2014
Discovery of Novel ROCK1 Inhibitors via Integrated Virtual Screening Strategy and Bioassays.
    Scientific reports, 2015, Nov-16, Volume: 5

    Topics: Actin Depolymerizing Factors; Amides; Animals; Atorvastatin; Binding Sites; Cerebral Hemorrhage; Databases, Chemical; Databases, Protein; Disease Models, Animal; Enzyme Activation; Human Umbilical Vein Endothelial Cells; Humans; Inhibitory Concentration 50; Molecular Docking Simulation; Phosphorylation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Pyridines; Pyrroles; rho-Associated Kinases; Signal Transduction; Structure-Activity Relationship; Zebrafish

2015
GSK-3β inhibitor TWS119 attenuates rtPA-induced hemorrhagic transformation and activates the Wnt/β-catenin signaling pathway after acute ischemic stroke in rats.
    Molecular neurobiology, 2016, Volume: 53, Issue:10

    Topics: Animals; Blood-Brain Barrier; Brain; Brain Edema; Brain Ischemia; Cerebral Hemorrhage; Claudin-3; Glycogen Synthase Kinase 3 beta; Infarction, Middle Cerebral Artery; Male; Permeability; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Stroke; Tissue Plasminogen Activator; Wnt Signaling Pathway; Zonula Occludens-1 Protein

2016
Colony stimulating factor 1 receptor inhibition eliminates microglia and attenuates brain injury after intracerebral hemorrhage.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2017, Volume: 37, Issue:7

    Topics: Aminopyridines; Animals; Brain; Brain Edema; Cerebral Hemorrhage; Cytokines; Disease Models, Animal; Humans; Mice; Mice, Inbred C57BL; Microglia; Neuroimaging; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Species Specificity

2017
Ischemic stroke: a cardiovascular risk equivalent? Lessons learned from the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial.
    The Canadian journal of cardiology, 2008, Volume: 24, Issue:9

    Topics: Atorvastatin; Cardiovascular Diseases; Cerebral Hemorrhage; Cholesterol; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Attack, Transient; Pyrroles; Randomized Controlled Trials as Topic; Secondary Prevention; Stroke

2008
Atorvastatin reduces the risk of cardiovascular events in patients with carotid atherosclerosis: a secondary analysis of the Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) trial.
    Stroke, 2008, Volume: 39, Issue:12

    Topics: Aged; Atorvastatin; Brain Ischemia; Carotid Stenosis; Cerebral Hemorrhage; Cholesterol, LDL; Coronary Disease; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Ischemic Attack, Transient; Male; Middle Aged; Pyrroles; Randomized Controlled Trials as Topic; Recurrence; Risk; Treatment Outcome

2008
Hemorrhagic stroke in the Stroke Prevention by Aggressive Reduction in Cholesterol Levels study.
    Neurology, 2009, Apr-21, Volume: 72, Issue:16

    Topics: Age Factors; Aged; Atorvastatin; Causality; Cerebral Hemorrhage; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Iatrogenic Disease; Intracranial Arteriosclerosis; Male; Pyrroles; Sex Factors

2009
Early atorvastatin reduces hemorrhage after acute cerebral ischemia in diabetic rats.
    The Journal of pharmacology and experimental therapeutics, 2009, Volume: 330, Issue:2

    Topics: Acute Disease; Animals; Atorvastatin; Brain Ischemia; Cerebral Hemorrhage; Diabetes Mellitus, Type 2; Drug Administration Schedule; Heptanoic Acids; Male; Pyrroles; Rats; Rats, Wistar; Time Factors

2009
Effect of atorvastatin in elderly patients with a recent stroke or transient ischemic attack.
    Neurology, 2009, Jul-21, Volume: 73, Issue:3

    Topics: Age Distribution; Age Factors; Aged; Anticholesteremic Agents; Atorvastatin; Cerebral Hemorrhage; Cholesterol, LDL; Clinical Trials as Topic; Heptanoic Acids; Humans; Iatrogenic Disease; Ischemic Attack, Transient; Pyrroles; Risk Assessment; Risk Factors; Stroke

2009
Simvastatin and atorvastatin improve neurological outcome after experimental intracerebral hemorrhage.
    Stroke, 2009, Volume: 40, Issue:10

    Topics: Animals; Apoptosis; Atorvastatin; Biomarkers; Brain; Brain Infarction; Bromodeoxyuridine; Cerebral Hemorrhage; Cytoprotection; Diffusion Magnetic Resonance Imaging; Disease Models, Animal; Doublecortin Domain Proteins; Doublecortin Protein; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Microtubule-Associated Proteins; Nerve Degeneration; Neurogenesis; Neuronal Plasticity; Neuropeptides; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Regeneration; Simvastatin; Treatment Outcome

2009
Vascular recovery promoted by atorvastatin and simvastatin after experimental intracerebral hemorrhage: magnetic resonance imaging and histological study.
    Journal of neurosurgery, 2011, Volume: 114, Issue:4

    Topics: Animals; Atorvastatin; Blood-Brain Barrier; Brain Edema; Cerebral Hemorrhage; Cerebrovascular Circulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunohistochemistry; Magnetic Resonance Imaging; Neovascularization, Physiologic; Nerve Regeneration; Pyrroles; Rats; Rats, Wistar; Simvastatin

2011
Effects of atorvastatin on pathological changes in brain tissue and plasma MMP-9 in rats with intracerebral hemorrhage.
    Cell biochemistry and biophysics, 2012, Volume: 62, Issue:1

    Topics: Animals; Atorvastatin; Brain; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Matrix Metalloproteinase 9; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Water

2012
Neuroprotective effect of atorvastatin involves suppression of TNF-α and upregulation of IL-10 in a rat model of intracerebral hemorrhage.
    Cell biochemistry and biophysics, 2013, Volume: 66, Issue:2

    Topics: Animals; Atorvastatin; Behavior, Animal; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Heptanoic Acids; Interleukin-10; Male; Microglia; Neuroprotective Agents; Pyrroles; Rats; Rats, Sprague-Dawley; Tumor Necrosis Factor-alpha; Up-Regulation

2013
The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) pathway regulates developmental cerebral-vascular stability via prenylation-dependent signalling pathway.
    Developmental biology, 2013, Jan-15, Volume: 373, Issue:2

    Topics: Alkyl and Aryl Transferases; Animals; Atorvastatin; cdc42 GTP-Binding Protein; Cerebral Hemorrhage; Cerebrum; Embryo, Nonmammalian; Endothelial Cells; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mice; Morpholinos; Polyisoprenyl Phosphates; Prenylation; Pyrroles; rhoA GTP-Binding Protein; Signal Transduction; Zebrafish

2013
Short-term effect of low-dose atorvastatin on haemorrheological parameters, platelet aggregation and endothelial function in patients with cerebrovascular disease and hyperlipidaemia.
    CNS drugs, 2004, Volume: 18, Issue:3

    Topics: Aged; Atorvastatin; Cerebral Hemorrhage; Cerebrovascular Disorders; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hyperlipidemias; Male; Middle Aged; Platelet Aggregation; Pyrroles; Time Factors

2004
HMG-CoA reductase inhibitor, atorvastatin, promotes sensorimotor recovery, suppressing acute inflammatory reaction after experimental intracerebral hemorrhage.
    Stroke, 2004, Volume: 35, Issue:7

    Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Atrophy; Brain; Cell Death; Cerebral Hemorrhage; Hematoma; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Models, Animal; Neuroprotective Agents; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Psychomotor Performance; Pyrroles; Rats; Rats, Sprague-Dawley

2004
Improvement in neurological outcome after administration of atorvastatin following experimental intracerebral hemorrhage in rats.
    Journal of neurosurgery, 2004, Volume: 101, Issue:1

    Topics: Animals; Atorvastatin; Brain; Cerebral Hemorrhage; Disease Models, Animal; Dose-Response Relationship, Drug; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Nervous System; Pyrroles; Rats; Rats, Wistar; Recovery of Function; Severity of Illness Index; Treatment Outcome

2004
Statin therapy after stroke or transient ischemic attack.
    The New England journal of medicine, 2006, Nov-30, Volume: 355, Issue:22

    Topics: Atorvastatin; Cardiovascular Diseases; Cerebral Hemorrhage; Cholesterol, LDL; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Risk Factors; Stroke; Transaminases

2006
High frequency of intracerebral hemorrhage in metastatic renal carcinoma patients with brain metastases treated with tyrosine kinase inhibitors targeting the vascular endothelial growth factor receptor.
    European urology, 2008, Volume: 53, Issue:2

    Topics: Adult; Aged; Benzenesulfonates; Brain Neoplasms; Carcinoma, Renal Cell; Cerebral Hemorrhage; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib

2008
High-dose atorvastatin after stroke or transient ischemic attack: The Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) Investigators.
    Journal of the cardiometabolic syndrome, 2008,Winter, Volume: 3, Issue:1

    Topics: Adult; Atorvastatin; Cardiovascular Diseases; Cerebral Hemorrhage; Cerebral Infarction; Cholesterol, LDL; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Ischemic Attack, Transient; Male; Pyrroles; Randomized Controlled Trials as Topic; Recurrence; Risk; Stroke

2008