pyrroles has been researched along with Cell Transformation, Neoplastic in 33 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (12.12) | 18.7374 |
| 1990's | 1 (3.03) | 18.2507 |
| 2000's | 10 (30.30) | 29.6817 |
| 2010's | 16 (48.48) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Han, KH; Jeong, IH; Jin, JO; Kim, MJ; Kwak, M; Lee, PC; Lee, TH; Park, MS | 1 |
| Cheng, W; Fang, S; Gong, YF; Guan, XY; Hu, L; Jiang, LX; Kong, FE; Li, HL; Li, L; Li, MM; Li, Y; Lin, G; Liu, M; Loong, JH; Ma, NF; Ma, S; Mo, JQ; Nam, Y; Ouyang, Q; Sun, Y; Tang, YQ; Wang, JG; Yan, Q; Yang, XD; Yuan, YF; Zhang, Y | 1 |
| Baldwin, GS; Dumesny, CJ; He, H; Huynh, N; Nikfarjam, M; Sandrin, MS; Wang, K; Yim, M | 1 |
| Feng, Y; Gu, Q; Ji, D; Li, J; Peng, W; Qian, W; Sun, Y; Wang, Q; Zhang, Y; Zhang, Z | 1 |
| Kuznietsova, HM; Ogloblya, OV; Rybalchenko, VK | 1 |
| Arias-Romero, LE; Chernoff, J; Hoeflich, KP; Huang, M; Villamar-Cruz, O | 1 |
| Kabadere, S; Kus, G; Oztopcu-Vatan, P; Uyar, R | 1 |
| Armeanu-Ebinger, S; Ellerkamp, V; Fuchs, J; Lieber, J; Vogt, F; Warmann, SW; Wenz, J | 1 |
| Aerts, S; Cools, J; Cox, L; de Bock, CE; Degryse, S; Demeyer, S; Fiers, M; Geerdens, E; Gianfelici, V; Gielen, O; Hulselmans, G; Jacobs, K; Meijerink, JP; Mentens, N; Tousseyn, T | 1 |
| Akashi, K; Annan, DA; Dosaka-Akita, H; Horlad, H; Jinushi, M; Kinoshita, I; Kitada, S; Komohara, Y; Morita, T; Nakayama, T; Ohnishi, K; Suzu, S; Takeya, M; Yamada, S | 1 |
| Kashiba, T; Sato, H; Shibata, Y; Ueno, K; Uzu, M; Yamada, R; Yamaura, K | 1 |
| Antaris, AL; Bao, Z; Chattopadhyay, N; Gambhir, SS; Hong, G; Jokerst, JV; Kurosawa, T; Mei, J; Pu, K; Rao, J; Shuhendler, AJ; Zhou, Y | 1 |
| Abraham, RT; Bray, K; Cochran, N; De Jesus, R; Eng, CH; Fantin, VR; Fitzgerald, SL; Frias, E; George, E; Hoffman, GR; Lemon, L; Liu, S; Lucas, J; McAllister, G; Murphy, LO; Nyfeler, B; Tkach, D; Toral-Barza, L; Ugwonali, S; Wang, Z | 1 |
| Aebischer, B; Akboga, MK; Akdamar, G; Alcalay, RN; Álvarez-Pérez, S; Aydogdu, S; Balci, KG; Barcaro, G; Bišová, K; Blanco, JL; Brewer, SH; Caruthers, SD; Ceylan, O; Chadwick, JA; Chang, DD; Che, JM; Chen, QQ; Chen, W; Chen, Z; Chung, M; Chung, W; Colecraft, HM; Coteli, E; Dogan, H; Dong, S; Elsig, S; Fahn, S; Fang, XJ; Feng, MG; Fenlon, EE; Floyd, KT; Fokdal, L; Ford, B; Fortunelli, A; Freudenberg, R; Gan-Or, Z; García, ME; Gillham, C; Giovannelli, D; Goertz, RS; Gulati, V; Haie-Meder, C; Hao, YY; Hatano, K; Hines, KJ; Hines, SM; Hirakawa, H; Hoskin, P; Hu, JH; Huang, P; Huang, Y; Hubicka, U; Inoue, Y; Ishii, N; Janssen, PM; Jin, Z; Johnson, A; Jürgenliemk-Schultz, I; Kaineder, K; Kamei, K; Kang, U; Karatas, F; Kash, TL; Katayama, Y; Keupp, J; Kirisits, C; Kisacik, H; Kodama, K; Kotzerke, J; Kryczyk, A; Kuhness, D; Kuo, S; Lanza, GM; Le Bris, N; Levin, DE; Levy, OA; Li, B; Li, H; Li, X; Liang, GD; Liang, Y; Liao, RQ; Lin, JT; Lindegaard, JC; Liong, C; Liu, B; Liu, C; Liu, GH; Liu, L; Liu, Q; Liu, X; Lowe, J; Lowery-Gionta, EG; Ma, YH; Maden, O; Mankad, V; Marder, KS; Marshall, SA; Martínez-Nevado, E; Maucksch, U; Mazeron, R; Mazzone, CM; Mazzoni, P; Mezricky, D; Mizokami, Y; Naumann, A; Navarro, M; Netzer, FP; Neurath, MF; Nie, Q; Oliva, P; Ozeke, O; Peláez, T; Pfeifer, L; Pleil, KE; Pomp, S; Pötter, R; Puckerin, AA; Rafael-Fortney, JA; Raman, SV; Rastogi, N; Řezanka, M; Řezanka, T; Rinker, JA; Rouleau, GA; Runge, R; Sahin, MD; Sakai, A; Schmieder, AH; Schmitz, AJ; Schultz, EJ; Šegedin, B; Sementa, L; Shen, Y; Shiotsuki, I; Shirahama, M; Staley, J; Starovoytov, V; Sterrer, M; Strobel, D; Sturdza, A; Subramanyam, P; Surnev, S; Swager, SA; Taeymans, J; Tan, H; Tan, LT; Tanderup, K; Temizhan, A; Terao, T; Thiele, TE; Tran, T; Tucker, MJ; Vetriani, C; Vítová, M; Wang, JP; Wang, L; Wang, M; Wang, X; Waters, CH; Weng, SX; Wickline, SA; Wildner, D; Wodarcyk, AJ; Wolf, P; Wu, L; Wu, YL; Wunderlich, G; Xiong, L; Xu, P; Yang, GS; Yang, XN; Yang, Y; Yayla, C; Ying, SH; Zachleder, V; Zhang, XG; Zhang, XK; Zhang, Y; Zheng, JY; Zhong, WZ; Zhu, J; Zhu, YJ; Żmudzki, P | 1 |
| Brugarolas, J; Bruick, RK; Chang, J; Chen, W; Christie, A; Courtney, K; Frenkel, E; Gardner, KH; Geiger, H; Hao, G; Hill, H; Holloman, E; Homayoun, F; Hwang, TH; Josey, JA; Joyce, A; Kapur, P; Kim, MS; Ma, Y; McKay, RM; Patel, N; Pavia-Jimenez, A; Pedrosa, I; Reeves, C; Rizzi, JP; Sun, X; Wallace, EM; Wong, T; Xie, XJ; Xie, Y; Yell, P; Yousuf, Q; Zhang, H; Zojwalla, N | 1 |
| Peter, S; Rohde, D; Tong, TQ | 1 |
| Beenakker, JW; Cui, C; Danen, EH; Ghotra, VP; He, S; Lamers, GE; Meijer, AH; Snaar-Jagalska, BE; Spaink, HP | 1 |
| Chung, YT; Li, H; Liao, J; Yan, L; Yang, AL; Yang, GY; Zhang, M; Zhang, W | 1 |
| Choi, HJ; Kamens, J; Schreiner, SJ; Smithgall, TE; Wilson, MB | 1 |
| Briesewitz, R; Bruner, RJ; Caligiuri, MA; Griffin, JH; Leung, J | 1 |
| Castedo, M; Feunteun, J; Horne, D; Kroemer, G; Lenoir, G; Medema, R; Perfettini, JL; Raslova, H; Roumier, T; Vainchenker, W; Valent, A; Yakushijin, K | 1 |
| Berlin, JD; Lockhart, AC; Lockhart, C | 1 |
| Capelle, HH; Erber, R; Farhadi, MR; Ullrich, A; Vajkoczy, P | 1 |
| Bernard-Pierrot, I; Brams, A; Caillault, A; Cappellen, D; Chopin, D; Diez de Medina, SG; Dunois-Lardé, C; Graff, G; Radvanyi, F; Ricol, D; Thiery, JP | 1 |
| Auersperg, N; Cosin, J; Dings, RP; Ramakrishnan, S; Schumacher, JJ; Subramanian, IV | 1 |
| Blay, JY | 1 |
| Chang, M; Chen, J; Elchuri, S; Fan, AC; Felsher, DW; Goldstein, MJ; Mitchell, DJ; Nolan, GP; Perez, OD; Shachaf, CM; Sharpe, O; Shirer, AE; Steinman, L; Youssef, S | 1 |
| Brandt, R; Hynes, NE; Wong, AM | 1 |
| Grunicke, H; Pushendorf, B; Werchau, H | 1 |
| Bradbury, EM; Crissman, HA; Gadbois, DM; Tobey, RA | 1 |
| Brdar, B; Reich, E; Rifkin, DB | 1 |
| Ossowski, L; Reich, E | 1 |
| Chandra, P; Gericke, D; Thorbeck, R; Zunino, F | 1 |
5 review(s) available for pyrroles and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
Topics: AC133 Antigen; Acenaphthenes; Acer; Acrosome Reaction; Adult; Agaricales; Aged; Aged, 80 and over; Animals; Animals, Zoo; Anti-Bacterial Agents; Anticoagulants; Antifungal Agents; Antimanic Agents; Antioxidants; Aortic Valve; Area Under Curve; ATP Binding Cassette Transporter, Subfamily G, Member 2; Bacillus; Bacterial Toxins; Bacterial Typing Techniques; Base Composition; Beauveria; Binge Drinking; Biomarkers; Bipolar Disorder; Blood Coagulation; Blotting, Western; Brachytherapy; Calcium Channels, L-Type; Carcinoma, Non-Small-Cell Lung; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Cell Wall; Cells, Cultured; Ceramics; Chi-Square Distribution; China; Chlorophyll; Chlorophyta; Chloroplasts; Cholesterol, HDL; Chromatography, High Pressure Liquid; Chromobacterium; Clostridium perfringens; Clozapine; Constriction, Pathologic; Coronary Artery Bypass; Corticotropin-Releasing Hormone; Cross-Sectional Studies; Cytochrome P-450 CYP2C9; Dental Porcelain; Dental Restoration Failure; Dental Stress Analysis; Designer Drugs; Diaminopimelic Acid; DNA Fingerprinting; DNA, Bacterial; Dose-Response Relationship, Drug; Dose-Response Relationship, Radiation; Drug Dosage Calculations; Drug Evaluation, Preclinical; Drug Resistance, Bacterial; Elasticity Imaging Techniques; Epsilonproteobacteria; Equipment Design; Ericaceae; Excitatory Amino Acid Antagonists; False Negative Reactions; Fatty Acids; Female; Food Analysis; Fresh Water; Gene Expression Regulation, Neoplastic; Glutathione; Graft Occlusion, Vascular; Heart Valve Prosthesis Implantation; Heart Ventricles; HEK293 Cells; Hemolymph; Humans; Hyaluronan Receptors; Hydrogen Peroxide; Hydrothermal Vents; Indoles; Inflammation Mediators; Inhibitory Concentration 50; Insecta; International Normalized Ratio; Isotope Labeling; Itraconazole; Kidney; Kinetics; Kruppel-Like Factor 4; Kruppel-Like Transcription Factors; Lamotrigine; Lanthanoid Series Elements; Limit of Detection; Linear Models; Lipid Peroxidation; Liver; Liver Cirrhosis; Logistic Models; Lung Neoplasms; Lymph Node Excision; Lymphatic Metastasis; Male; Malondialdehyde; Mediastinum; Metronidazole; Mice; Mice, Nude; Mice, Transgenic; Microbial Sensitivity Tests; Microscopy, Fluorescence; Middle Aged; Monocytes; Monomeric GTP-Binding Proteins; Multivariate Analysis; Myocytes, Cardiac; Neoplasm Staging; Neoplastic Stem Cells; Neural Pathways; Nitrates; Nucleic Acid Hybridization; Octamer Transcription Factor-3; Odds Ratio; Oxidation-Reduction; Oxidative Stress; Peptidoglycan; Phantoms, Imaging; Pharmacogenetics; Pharmacogenomic Variants; Phenotype; Phospholipids; Photolysis; Photosynthesis; Phylogeny; Plant Extracts; Polychaeta; Polymerase Chain Reaction; Polymorphism, Single Nucleotide; Positron Emission Tomography Computed Tomography; Predictive Value of Tests; Preoperative Care; Prostatic Neoplasms; Pseudomonas aeruginosa; Pyrimidines; Pyrroles; Quorum Sensing; Radiology, Interventional; Radiopharmaceuticals; Radiotherapy Dosage; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Reference Values; Regression Analysis; Retrospective Studies; Reverse Transcriptase Polymerase Chain Reaction; Rhizosphere; Risk Factors; RNA, Ribosomal, 16S; ROC Curve; Rutin; Saphenous Vein; Seawater; Selenium; Semen Preservation; Sensitivity and Specificity; Septal Nuclei; Sequence Analysis, DNA; Serum Albumin; Serum Albumin, Human; Shear Strength; Sodium Pertechnetate Tc 99m; Sodium-Hydrogen Exchangers; Soil Microbiology; SOXB1 Transcription Factors; Spain; Species Specificity; Sperm Motility; Spermatozoa; Spheroids, Cellular; Spores, Fungal; Stroke; Superoxide Dismutase; Swine; Tandem Mass Spectrometry; Technetium Compounds; Technetium Tc 99m Exametazime; Technetium Tc 99m Sestamibi; Temperature; Thiosulfates; Thrombosis; Thyroid Neoplasms; Transducers; Transfection; Transplantation, Heterologous; Treatment Outcome; Triazines; Tumor Burden; Urocortins; Uterine Cervical Neoplasms; Vacuoles; Valproic Acid; Ventral Tegmental Area; Vitamin K 2; Vitamin K Epoxide Reductases; Warfarin; Water Microbiology; Young Adult | 2016 |
Progress in the management of advanced renal cell carcinoma (RCC).
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzenesulfonates; Bevacizumab; Carcinoma, Renal Cell; Cell Transformation, Neoplastic; Everolimus; Humans; Indoles; Kidney Neoplasms; Neovascularization, Pathologic; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Sirolimus; Sorafenib; Sunitinib; Von Hippel-Lindau Tumor Suppressor Protein | 2010 |
The epidermal growth factor receptor as a target for colorectal cancer therapy.
Topics: Aminoquinolines; Aniline Compounds; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cell Transformation, Neoplastic; Cetuximab; Colorectal Neoplasms; Disease Progression; ErbB Receptors; Erlotinib Hydrochloride; Gefitinib; Humans; Lapatinib; Organic Chemicals; Panitumumab; Prognosis; Pyrimidines; Pyrroles; Quinazolines; Signal Transduction | 2005 |
Mechanism of action of distamycin A and other antibiotics with antiviral activity.
Topics: Anti-Bacterial Agents; Antiviral Agents; Bleomycin; Cell Transformation, Neoplastic; Cell-Free System; Daunorubicin; Distamycins; DNA; DNA Nucleotidyltransferases; DNA-Directed RNA Polymerases; Guanidines; Poxviridae; Protein Biosynthesis; Pyrroles; Rifamycins; RNA; Virus Diseases; Virus Replication; Viruses | 1976 |
[Molecular basis of viral induced tumors (author's transl)].
Topics: Amidines; Animals; Anti-Bacterial Agents; Cell Transformation, Neoplastic; Daunorubicin; DNA Nucleotidyltransferases; DNA Viruses; Doxorubicin; Humans; Neoplasms; Oncogenic Viruses; Peptides; Pyrroles; RNA Viruses | 1973 |
28 other study(ies) available for pyrroles and Cell Transformation, Neoplastic
| Article | Year |
|---|---|
USP14 Inhibition Regulates Tumorigenesis by Inducing Autophagy in Lung Cancer In Vitro.
Topics: Autophagy; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Humans; Lung Neoplasms; Pyrroles; RNA Interference; RNA, Small Interfering; Ubiquitin Thiolesterase | 2019 |
A hepatocyte differentiation model reveals two subtypes of liver cancer with different oncofetal properties and therapeutic targets.
Topics: Aminopyridines; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell Differentiation; Cell Line; Cell Transformation, Neoplastic; Cohort Studies; Disease-Free Survival; E2F1 Transcription Factor; Female; Gene Expression Profiling; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Hepatectomy; Hepatocytes; Human Embryonic Stem Cells; Humans; Hydroxyquinolines; Isoquinolines; Kaplan-Meier Estimate; Liver; Liver Neoplasms; Male; Mice; Middle Aged; Prognosis; Pyridines; Pyrroles; Signal Transduction; Smad3 Protein; Xenograft Model Antitumor Assays | 2020 |
Depletion of p21-activated kinase 1 up-regulates the immune system of APC
Topics: Animals; Biomarkers; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Disease Models, Animal; Genes, APC; Genotype; Immune System; Immunohistochemistry; Immunomodulation; Leukocyte Count; Lymphocytes; Mice; Mice, Knockout; Neutrophils; p21-Activated Kinases; Polycomb Repressive Complex 1; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Pyrazoles; Pyrroles | 2017 |
NMI promotes cell proliferation through TGFβ/Smad pathway by upregulating STAT1 in colorectal cancer.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Colorectal Neoplasms; Humans; Intracellular Signaling Peptides and Proteins; Isoquinolines; Prognosis; Pyridines; Pyrroles; RNA Interference; RNA, Small Interfering; Smad Proteins; STAT1 Transcription Factor; Transcriptional Activation; Transforming Growth Factor beta1 | 2020 |
Impact of dihydropyrrol derivative on the normal colonic mucosa of DMH-induced colon cancer rats compared with 5-fluorouracil.
Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Fluorouracil; Intestinal Mucosa; Male; Pyrroles; Pyrrolidinones; Rats; Rats, Wistar | 2013 |
Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells.
Topics: Animals; Apoptosis; beta Catenin; Blotting, Western; Breast Neoplasms; Cell Line; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Epithelial Cells; Humans; Mice; Mice, Inbred ICR; Mice, Knockout; Mice, SCID; Mice, Transgenic; p21-Activated Kinases; Pyrazoles; Pyrroles; Receptor, ErbB-2; RNA Interference; Xenograft Model Antitumor Assays | 2013 |
Licofelone abolishes survival of carcinogenic fibroblasts by inducing apoptosis.
Topics: Analysis of Variance; Animals; Apoptosis; Cell Transformation, Neoplastic; DNA Primers; Dose-Response Relationship, Drug; Embryo, Mammalian; Fibroblasts; Flow Cytometry; Fluorouracil; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Tetrazolium Salts; Thiazoles; Time Factors; Trypan Blue; Tumor Cells, Cultured | 2014 |
BH3-mimetic drugs prevent tumour onset in an orthotopic mouse model of hepatoblastoma.
Topics: Animals; Biomimetic Materials; Biphenyl Compounds; Cell Transformation, Neoplastic; Cells, Cultured; Disease Models, Animal; Drug Evaluation, Preclinical; Hepatoblastoma; Humans; Indoles; Liver Neoplasms; Mice; Mice, Inbred C57BL; Mice, Inbred NOD; Mice, Nude; Mice, Transgenic; Nitrophenols; Peptide Fragments; Piperazines; Proto-Oncogene Proteins; Pyrroles; Sulfonamides | 2014 |
JAK3 mutants transform hematopoietic cells through JAK1 activation, causing T-cell acute lymphoblastic leukemia in a mouse model.
Topics: Acute Disease; Animals; Cell Transformation, Neoplastic; Disease Models, Animal; Enzyme Activation; Janus Kinase 1; Janus Kinase 3; Leukemia, T-Cell; Male; Mice; Mice, Inbred BALB C; Mutation; Piperidines; Pyrimidines; Pyrroles; Signal Transduction; T-Lymphocytes | 2014 |
The Coordinated Actions of TIM-3 on Cancer and Myeloid Cells in the Regulation of Tumorigenicity and Clinical Prognosis in Clear Cell Renal Cell Carcinomas.
Topics: Aged; Animals; Antineoplastic Agents; Apoptosis; Biomarkers, Tumor; Carcinoma, Renal Cell; Cell Transformation, Neoplastic; Coculture Techniques; Drug Resistance, Neoplasm; Female; Hepatitis A Virus Cellular Receptor 2; Heterografts; Humans; Indoles; Kaplan-Meier Estimate; Kidney Neoplasms; Macrophages; Male; Membrane Proteins; Mice, Inbred NOD; Mice, SCID; Middle Aged; Neoplasm Proteins; Neoplasm Transplantation; Prognosis; Pyrroles; Sirolimus; Sunitinib; Tumor Cells, Cultured | 2015 |
Effect of enhanced expression of connexin 43 on sunitinib-induced cytotoxicity in mesothelioma cells.
Topics: Antineoplastic Agents; Apoptosis; bcl-2-Associated X Protein; Cell Line, Tumor; Cell Transformation, Neoplastic; Connexin 43; Drug Resistance, Neoplasm; Gap Junctions; Gene Expression; Gene Expression Regulation, Neoplastic; Humans; Indoles; Mesothelioma; Pyrroles; Receptor Protein-Tyrosine Kinases; Signal Transduction; Sunitinib | 2015 |
Diketopyrrolopyrrole-Based Semiconducting Polymer Nanoparticles for In Vivo Photoacoustic Imaging.
Topics: Animals; Cell Transformation, Neoplastic; HeLa Cells; Humans; Ketones; Mice; Models, Molecular; Molecular Conformation; Nanoparticles; Photoacoustic Techniques; Polymers; Pyrroles; Semiconductors | 2015 |
Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy.
Topics: Antineoplastic Agents; Autophagy; Autophagy-Related Protein 7; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Chloroquine; Drug Resistance, Neoplasm; Erlotinib Hydrochloride; Gene Knockout Techniques; Humans; Indoles; Mutation; Protein Kinase Inhibitors; Proto-Oncogene Proteins p21(ras); Pyrroles; Radiation Tolerance; Sunitinib; Ubiquitin-Activating Enzymes | 2016 |
Targeting renal cell carcinoma with a HIF-2 antagonist.
Topics: Animals; Aryl Hydrocarbon Receptor Nuclear Translocator; Basic Helix-Loop-Helix Transcription Factors; Binding Sites; Carcinoma, Renal Cell; Cell Line, Tumor; Cell Transformation, Neoplastic; Drug Resistance, Neoplasm; Erythropoietin; Female; Gene Expression Regulation, Neoplastic; Humans; Indans; Indoles; Kidney Neoplasms; Male; Mice; Mice, Inbred NOD; Mice, SCID; Molecular Targeted Therapy; Mutation; Pyrroles; Reproducibility of Results; Sulfones; Sunitinib; Xenograft Model Antitumor Assays | 2016 |
Neutrophil-mediated experimental metastasis is enhanced by VEGFR inhibition in a zebrafish xenograft model.
Topics: Animals; Beclomethasone; Breast Neoplasms; Cell Movement; Cell Transformation, Neoplastic; Disease Models, Animal; Endothelial Cells; Humans; Indoles; Mice; Myeloid Cells; Neoplasm Metastasis; Neutrophils; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Signal Transduction; Sunitinib; Xenograft Model Antitumor Assays; Zebrafish | 2012 |
Atorvastatin inhibits pancreatic carcinogenesis and increases survival in LSL-KrasG12D-LSL-Trp53R172H-Pdx1-Cre mice.
Topics: Animals; Atorvastatin; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Survival; Cell Transformation, Neoplastic; Epoxide Hydrolases; Heptanoic Acids; Homeodomain Proteins; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Inflammation; Ki-67 Antigen; Mice; Pancreas; Pancreatic Neoplasms; Phosphorylation; Prenylation; Proto-Oncogene Proteins c-raf; Proto-Oncogene Proteins p21(ras); Pyrroles; Trans-Activators; Transcriptome; Tumor Suppressor Protein p53 | 2013 |
Selective pyrrolo-pyrimidine inhibitors reveal a necessary role for Src family kinases in Bcr-Abl signal transduction and oncogenesis.
Topics: Apoptosis; Cell Division; Cell Transformation, Neoplastic; DNA-Binding Proteins; Dose-Response Relationship, Drug; Enzyme Activation; Enzyme Inhibitors; Fusion Proteins, bcr-abl; Granulocyte-Macrophage Colony-Stimulating Factor; Humans; K562 Cells; Leukemia, Erythroblastic, Acute; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Milk Proteins; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinases; Monocytes; Neoplasm Proteins; Phosphorylation; Protein Processing, Post-Translational; Pyrimidines; Pyrroles; Signal Transduction; src-Family Kinases; STAT5 Transcription Factor; Trans-Activators; Tumor Cells, Cultured | 2002 |
Discovery of a fusion kinase in EOL-1 cells and idiopathic hypereosinophilic syndrome.
Topics: Adult; Amino Acid Sequence; Animals; Antineoplastic Agents; Base Sequence; Benzamides; Blotting, Western; Cell Division; Cell Line; Cell Survival; Cell Transformation, Neoplastic; Dose-Response Relationship, Drug; Enzyme Inhibitors; Eosinophils; Gene Deletion; Humans; Hypereosinophilic Syndrome; Imatinib Mesylate; Indoles; Male; Mice; Models, Chemical; Models, Genetic; Molecular Sequence Data; Peptides; Phthalazines; Piperazines; Precipitin Tests; Protein Structure, Tertiary; Pyridines; Pyrimidines; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Recombinant Fusion Proteins; Recurrence; Tyrosine | 2003 |
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.
Topics: Amino Acid Chloromethyl Ketones; Aneuploidy; Antibiotics, Antineoplastic; Apoptosis; Azepines; Caspase 2; Caspase 3; Caspase Inhibitors; Caspases; CD4 Antigens; Cell Division; Cell Fusion; Cell Line, Tumor; Cell Transformation, Neoplastic; Centrosome; Checkpoint Kinase 2; Colonic Neoplasms; Cysteine Proteinase Inhibitors; DNA Damage; Doxorubicin; Genes, env; Giant Cells; HeLa Cells; Humans; Intracellular Membranes; Metaphase; Mitochondria; Mitosis; Models, Biological; Protein Serine-Threonine Kinases; Pyrroles; RNA Interference; Transfection | 2004 |
Combined inhibition of vascular endothelial growth factor and platelet-derived growth factor signaling: effects on the angiogenesis, microcirculation, and growth of orthotopic malignant gliomas.
Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Indoles; Mice; Mice, Nude; Microcirculation; Microscopy, Fluorescence; Microscopy, Video; Neoplasm Transplantation; Neovascularization, Pathologic; Oxindoles; Platelet-Derived Growth Factor; Propionates; Protein-Tyrosine Kinases; Pyrroles; Rats; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Transplantation, Heterologous; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2 | 2005 |
Oncogenic properties of the mutated forms of fibroblast growth factor receptor 3b.
Topics: Animals; Cell Transformation, Neoplastic; DNA Mutational Analysis; Epithelial Cells; Female; Fibroblasts; Humans; Mice; Mice, Nude; Protein Isoforms; Pyrroles; Receptor, Fibroblast Growth Factor, Type 3; Reverse Transcriptase Polymerase Chain Reaction; RNA, Small Interfering; Transfection; Transplantation, Heterologous; Urinary Bladder Neoplasms | 2006 |
Modulation of angiogenic phenotype alters tumorigenicity in rat ovarian epithelial cells.
Topics: Angiogenesis Inhibitors; Animals; Cell Growth Processes; Cell Transformation, Neoplastic; Endostatins; Female; Indoles; Neovascularization, Pathologic; Ovarian Neoplasms; Pyrroles; Rats; Transfection; Vascular Endothelial Growth Factor A | 2007 |
[Anti-angiogenetic agents for solid tumors].
Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Cell Transformation, Neoplastic; Humans; Indoles; Neoplasms; Neovascularization, Pathologic; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A | 2007 |
Inhibition of HMGcoA reductase by atorvastatin prevents and reverses MYC-induced lymphomagenesis.
Topics: Animals; Atorvastatin; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Flow Cytometry; Gene Expression Profiling; Glycine; Heptanoic Acids; Humans; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lymphoma; Mice; Mice, Transgenic; Mutation; Oncogene Protein p55(v-myc); Phosphoproteins; Phosphorylation; Precancerous Conditions; Pyrroles; ras Proteins; Signal Transduction; Survival Rate | 2007 |
Mammary glands reconstituted with Neu/ErbB2 transformed HC11 cells provide a novel orthotopic tumor model for testing anti-cancer agents.
Topics: Animals; Antineoplastic Agents; Cell Division; Cell Line, Transformed; Cell Transformation, Neoplastic; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Genes, erbB-2; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neoplasm Transplantation; Paclitaxel; Pyrimidines; Pyrroles; Receptor, ErbB-2 | 2001 |
Multiple kinase arrest points in the G1 phase of nontransformed mammalian cells are absent in transformed cells.
Topics: Alkaloids; Carbazoles; Cell Cycle; Cell Transformation, Neoplastic; Cells, Cultured; Humans; In Vitro Techniques; Indole Alkaloids; Indoles; Interphase; Protein Kinase Inhibitors; Protein Kinases; Pyrroles; Staurosporine | 1992 |
Studies of Rous sarcoma virus. Effects of nucleoside analogues on virus synthesis.
Topics: Animals; Avian Sarcoma Viruses; Bromine; Cell Fractionation; Cell Nucleus; Cell Transformation, Neoplastic; Chick Embryo; Cytoplasm; Dactinomycin; DNA; Electrophoresis, Polyacrylamide Gel; Fibroblasts; Fluorine; Protein Biosynthesis; Pyrimidines; Pyrroles; Ribonucleosides; RNA; RNA, Viral; Uridine; Viral Proteins; Virus Replication | 1973 |
Effects of nucleoside analogs on transcription of simian virus 40.
Topics: Animals; Bromine; Cell Line; Cell Transformation, Neoplastic; DNA, Viral; Fibroblasts; Floxuridine; Genetics, Microbial; Haplorhini; Kidney; Mice; Nucleic Acid Hybridization; Phosphorus Isotopes; Pyrimidines; Pyrroles; Ribonucleosides; RNA, Messenger; RNA, Ribosomal; RNA, Viral; Simian virus 40; Transcription, Genetic; Tritium; Virus Replication | 1972 |