pyrroles has been researched along with Cardiomegaly in 25 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (12.00) | 18.7374 |
| 1990's | 1 (4.00) | 18.2507 |
| 2000's | 9 (36.00) | 29.6817 |
| 2010's | 10 (40.00) | 24.3611 |
| 2020's | 2 (8.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gupte, SA; Jacob, C; Jordan, A; Kitagawa, A; McMurtry, IF; Waddell, I | 1 |
| Bahtiar, A; Fujio, Y; Kametani, Y; Kobayashi, A; Maeda, M; Matsumoto, K; Miyake, Y; Mori, S; Obana, M; Tanaka, S; Tomimatsu, M; Wahyuni, T; Yamamoto, A | 1 |
| Aronovitz, MJ; Baumgartner, RA; Baur, WE; Blanton, RM; Calamaras, TD; Cooper, CW; Davis, RJ; Kapur, NK; Karas, RH; Li, N; McLaughlin, AL; Qiao, X; Richards, DA; Tam, K; Wang, GR | 1 |
| Fukumoto, Y; Kudo, S; Liao, JK; Minami, T; Nochioka, K; Shiba, N; Shimokawa, H; Takai, Y; Tanaka, S; Williams, CL | 1 |
| Amini, R; Jahanbakhsh, Z; Mohammadi, MT; Shekarforoush, S | 1 |
| Bu, L; Cheng, Z; Dong, D; Huang, T; Shen, B; Tu, Y; Wan, L; Zhao, D | 1 |
| Al-Arifi, MN; Ansari, MA; El Gendy, MA; Korashy, HM; Maayah, ZH | 1 |
| Deng, Y; Guo, X; Liu, H; Shang, J; Yuan, X; Zhu, D | 1 |
| Engle, SK; Watson, DE | 1 |
| Brown, MB; Goodwill, AG; Kline, JA; McCarthy, BP; Neto-Neves, EM; Persohn, SA; Rezania, S; Territo, PR; Zaretskaia, MV | 1 |
| Ehmke, H; El-Armouche, A; Eschenhagen, T; Grimm, M; Höppner, G; Schmechel, A; Schwoerer, AP | 1 |
| Cui, W; Du, J; Han, M; Liu, DM; Liu, F; Lu, JC; Yin, HN; Zhang, HL; Zhang, K | 1 |
| Lombardi, R; Marian, AJ; Nagueh, SF; Tan, Y; Wang, J; Willerson, JT | 1 |
| Liu, XG; Miao, N; Mu, SH; Sui, MS; Xie, RJ; Zhao, SL | 1 |
| Laguna, JC; Planavila, A; Vázquez-Carrera, M | 1 |
| Liu, YX; Sheng, L; Ye, P | 1 |
| Ge, CJ; Hu, SJ; Kang, L | 1 |
| Fang, Q; Hu, SJ; Kang, L | 1 |
| Bezerra, DG; Lacerda Andrade, LM; Mandarim-de-Lacerda, CA; Pinto da Cruz, FO | 1 |
| Asakura, M; Asanuma, H; Kato, H; Kim, J; Kitakaze, M; Liao, Y; Minamino, T; Ogai, A; Takashima, S; Zhao, H | 1 |
| Gamble, W; Meyrick, B; Reid, L | 1 |
| Dzwonczyk, S; Grover, GJ; Monticello, TM | 1 |
| Böhm, M; Kilter, H; Konkol, C; Laufs, U; Nickenig, G; Wassmann, S | 1 |
| Johnson, WD; Lalich, JL; Raczniak, TJ; Shumaker, RC | 1 |
| Allen, JR; Chesney, CF; Hsu, IC | 1 |
1 trial(s) available for pyrroles and Cardiomegaly
| Article | Year |
|---|---|
Statins exert the pleiotropic effects through small GTP-binding protein dissociation stimulator upregulation with a resultant Rac1 degradation.
Topics: Adaptor Proteins, Signal Transducing; Angiotensin II; Animals; Atorvastatin; Biomarkers; Cardiomegaly; Cells, Cultured; Cholesterol; Cholesterol, LDL; Coronary Vessels; Cross-Over Studies; Cytoskeletal Proteins; Disease Models, Animal; Dose-Response Relationship, Drug; Fibrosis; Glycogen Synthase Kinase 3; Glycogen Synthase Kinase 3 beta; Guanine Nucleotide Exchange Factors; Heptanoic Acids; Human Umbilical Vein Endothelial Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Japan; Male; Mice; Mice, Knockout; Neuropeptides; Oxidative Stress; Phosphatidylinositol 3-Kinase; Pravastatin; Proto-Oncogene Proteins c-akt; Pyrroles; Quinolines; rac GTP-Binding Proteins; rac1 GTP-Binding Protein; RNA Interference; Signal Transduction; Transfection | 2013 |
24 other study(ies) available for pyrroles and Cardiomegaly
| Article | Year |
|---|---|
Inhibition of Glucose-6-Phosphate Dehydrogenase Activity Attenuates Right Ventricle Pressure and Hypertrophy Elicited by VEGFR Inhibitor + Hypoxia.
Topics: Animals; Blood Pressure; Cardiomegaly; Cell Hypoxia; Cells, Cultured; DNA Methylation; Enzyme Inhibitors; Female; Glucosephosphate Dehydrogenase; Humans; Hypertension, Pulmonary; Indoles; Male; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Smooth Muscle; Pyrroles; Ventricular Function, Right | 2021 |
Maresin-1 induces cardiomyocyte hypertrophy through IGF-1 paracrine pathway.
Topics: Animals; Cardiomegaly; Cardiotonic Agents; Disease Models, Animal; Docosahexaenoic Acids; Gene Expression Regulation; Insulin-Like Growth Factor I; Male; Mice; Mice, Inbred C57BL; Myocardial Infarction; Myocytes, Cardiac; Nuclear Receptor Subfamily 1, Group F, Member 1; Paracrine Communication; Phosphatidylinositol 3-Kinases; Primary Cell Culture; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Rats; Ribonucleosides; Signal Transduction; Sulfonamides; Thiophenes; Wortmannin | 2021 |
Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload.
Topics: Animals; Cardiac Output; Cardiomegaly; Cells, Cultured; Humans; Male; MAP Kinase Kinase 4; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinase Kinase 11; Myocytes, Cardiac; Protein Kinase Inhibitors; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling | 2019 |
Effects of atorvastatin on the hypertension-induced oxidative stress in the rat brain.
Topics: Animals; Atorvastatin; Blood Pressure; Brain; Cardiomegaly; Catalase; Glutathione; Heptanoic Acids; Hypertension; Male; Malondialdehyde; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
MicroRNA-22 downregulation by atorvastatin in a mouse model of cardiac hypertrophy: a new mechanism for antihypertrophic intervention.
Topics: Angiotensin II; Animals; Anticholesteremic Agents; Atorvastatin; Atrial Natriuretic Factor; Cardiomegaly; Cells, Cultured; Disease Models, Animal; Down-Regulation; Heptanoic Acids; Male; Mice; MicroRNAs; Myocardium; Myocytes, Cardiac; Myosin Heavy Chains; Natriuretic Peptide, Brain; Oligonucleotides, Antisense; Phosphoric Monoester Hydrolases; PTEN Phosphohydrolase; Pyrroles; Rats | 2013 |
Development of cardiac hypertrophy by sunitinib in vivo and in vitro rat cardiomyocytes is influenced by the aryl hydrocarbon receptor signaling pathway.
Topics: Animals; Cardiomegaly; Cell Survival; Cells, Cultured; Cytochrome P-450 CYP1A1; Dose-Response Relationship, Drug; Enzymes; Gene Expression Regulation; Imidazoles; Indoles; Male; Myocytes, Cardiac; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptors, Aryl Hydrocarbon; Resveratrol; Signal Transduction; Stilbenes; Sunitinib | 2014 |
Atorvastatin attenuates myocardial remodeling induced by chronic intermittent hypoxia in rats: partly involvement of TLR-4/MYD88 pathway.
Topics: Animals; Atorvastatin; Cardiomegaly; Cytokines; Heart; Heptanoic Acids; Hypoxia; Male; Myeloid Differentiation Factor 88; Myocardium; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Sleep Apnea, Obstructive; Toll-Like Receptor 4; Ventricular Remodeling | 2014 |
Natriuretic Peptides as Cardiovascular Safety Biomarkers in Rats: Comparison With Blood Pressure, Heart Rate, and Heart Weight.
Topics: Animals; Atrial Natriuretic Factor; Biomarkers; Blood Pressure; Cardiomegaly; Heart Rate; Indoles; Male; Minoxidil; Natriuretic Peptide, Brain; NG-Nitroarginine Methyl Ester; Nifedipine; Organ Size; Peptide Fragments; Prostaglandins F, Synthetic; Pyrroles; Rats; Rats, Sprague-Dawley; Sunitinib; Thyroxine | 2016 |
Chronic Embolic Pulmonary Hypertension Caused by Pulmonary Embolism and Vascular Endothelial Growth Factor Inhibition.
Topics: Animals; Cardiomegaly; Cell Proliferation; Chronic Disease; Heart Function Tests; Hemodynamics; Hyperplasia; Hypertension, Pulmonary; Hypoxia; Indoles; Ki-67 Antigen; Lung; Male; Microspheres; Oxygen Consumption; P-Selectin; Partial Pressure; Physical Conditioning, Animal; Plasminogen Activator Inhibitor 1; Polystyrenes; Pulmonary Embolism; Pyrroles; Rats, Sprague-Dawley; Tissue Inhibitor of Metalloproteinase-1; Vascular Endothelial Growth Factor A; Ventricular Dysfunction | 2017 |
Treatment with atorvastatin partially protects the rat heart from harmful catecholamine effects.
Topics: Adrenergic beta-Agonists; Animals; Atorvastatin; Atrial Natriuretic Factor; Cardiomegaly; Cell Membrane; Circadian Rhythm; Cytosol; GTP-Binding Protein alpha Subunits, Gs; GTP-Binding Protein gamma Subunits; Heart; Heart Rate; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Infusion Pumps, Implantable; Isoproterenol; Male; Myocardial Contraction; Myocardium; Protein Transport; Pyrroles; Rats; Rats, Wistar; RNA, Messenger | 2009 |
Additive beneficial effects of amlodipine and atorvastatin in reversing advanced cardiac hypertrophy in elderly spontaneously hypertensive rats.
Topics: Aging; Amlodipine; Animals; Anticholesteremic Agents; Antihypertensive Agents; Atorvastatin; Cardiomegaly; Drug Synergism; Drug Therapy, Combination; Fibrosis; Heart Failure, Diastolic; Hemodynamics; Heptanoic Acids; Myocytes, Cardiac; NADPH Oxidases; Natriuretic Peptide, Brain; Oxidative Stress; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Reactive Oxygen Species; Superoxide Dismutase; Ventricular Dysfunction, Left | 2009 |
Atorvastatin and cardiac hypertrophy and function in hypertrophic cardiomyopathy: a pilot study.
Topics: Adult; Aged; Aged, 80 and over; Anticholesteremic Agents; Atorvastatin; Cardiomegaly; Cardiomyopathy, Hypertrophic; Death, Sudden, Cardiac; Female; Genetic Predisposition to Disease; Heptanoic Acids; Humans; Male; Middle Aged; Pilot Projects; Pyrroles; Statistics as Topic; Treatment Outcome; Young Adult | 2010 |
[Atorvastatin attenuates parathyroid hormone 1-34 induced cardiomyocytes hypertrophy through downregulating K-Ras-ERK1/2 pathway].
Topics: Animals; Animals, Newborn; Atorvastatin; Cardiomegaly; Cells, Cultured; Heptanoic Acids; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 3; Myocytes, Cardiac; Parathyroid Hormone; Pyrroles; Rats; Rats, Wistar | 2012 |
Atorvastatin improves peroxisome proliferator-activated receptor signaling in cardiac hypertrophy by preventing nuclear factor-kappa B activation.
Topics: Animals; Atorvastatin; Cardiomegaly; Heart; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; NF-kappa B; Peroxisome Proliferator-Activated Receptors; Pressure; Protein Isoforms; Protein Subunits; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Signal Transduction | 2005 |
[Atorvastatin upregulates the expression of PPAR alpha/gamma and inhibits the hypertrophy of cardiac myocytes in vitro].
Topics: Angiotensin II; Animals; Atorvastatin; Cardiomegaly; Cells, Cultured; Gene Expression Regulation; Heptanoic Acids; Myocytes, Cardiac; PPAR alpha; PPAR-beta; Pyrroles; Rats; Rats, Wistar; Up-Regulation | 2005 |
Beneficial effect of atorvastatin on left ventricular remodeling in spontaneously hypertensive rats.
Topics: Animals; Apoptosis; Atorvastatin; Blood Pressure; Cardiomegaly; Collagen; Cyclin-Dependent Kinase Inhibitor p27; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Myocardium; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Remodeling | 2007 |
Regulation of phospholamban and sarcoplasmic reticulum Ca2+-ATPase by atorvastatin: implication for cardiac hypertrophy.
Topics: Animals; Atorvastatin; Calcium-Binding Proteins; Cardiomegaly; Gene Expression Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sarcoplasmic Reticulum Calcium-Transporting ATPases; Systole | 2007 |
Atorvastatin attenuates cardiomyocyte loss in adult rats from protein-restricted dams.
Topics: Animals; Atorvastatin; Blood Pressure; Body Mass Index; Cardiomegaly; Diet, Protein-Restricted; Fibrosis; Heptanoic Acids; Hypertrophy, Left Ventricular; Male; Myocardial Reperfusion; Myocytes, Cardiac; Perfusion; Pyrroles; Rats; Rats, Wistar | 2008 |
Atorvastatin slows the progression of cardiac remodeling in mice with pressure overload and inhibits epidermal growth factor receptor activation.
Topics: Animals; Atorvastatin; Cardiomegaly; Disease Progression; ErbB Receptors; Extracellular Signal-Regulated MAP Kinases; Heart Failure; Heparin-binding EGF-like Growth Factor; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Signaling Peptides and Proteins; Male; Mice; Mice, Inbred C57BL; Myocytes, Cardiac; Natriuretic Peptide, Brain; Phosphorylation; Pyrroles; Ventricular Function, Left | 2008 |
Development of Crotalaria pulmonary hypertension: hemodynamic and structural study.
Topics: Animals; Blood Gas Analysis; Body Temperature; Cardiomegaly; Hemodynamics; Hypertension, Pulmonary; Male; Monocrotaline; Pulmonary Circulation; Pyrroles; Pyrrolizidine Alkaloids; Rats | 1980 |
Comparative cardioprotective effects of cromakalim and diltiazem in ischemic hypertrophied rat hearts.
Topics: Animals; Benzopyrans; Blood Pressure; Cardiomegaly; Cromakalim; Diltiazem; Heart; Heart Rate; L-Lactate Dehydrogenase; Male; Myocardial Contraction; Myocardial Ischemia; Myocardial Reperfusion Injury; Myocardium; Pyrroles; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Ventricular Function, Left | 1996 |
Impact of HMG CoA reductase inhibition on small GTPases in the heart.
Topics: Angiotensin II; Animals; Atorvastatin; Atrial Natriuretic Factor; Cardiac Myosins; Cardiomegaly; Cell Membrane; Cells, Cultured; Gene Expression Regulation; GTP Phosphohydrolases; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypolipidemic Agents; JNK Mitogen-Activated Protein Kinases; Male; MAP Kinase Kinase 4; Mitogen-Activated Protein Kinase Kinases; Myocardium; Myosin Light Chains; Pyrroles; rac1 GTP-Binding Protein; Rats; Rats, Sprague-Dawley; rhoA GTP-Binding Protein; RNA, Messenger; Simvastatin | 2002 |
Fibrin thrombosis in monocrotaline pyrrole-induced cor pulmonale in rats.
Topics: Animals; Cardiomegaly; Endothelium; Fibrin; Hypertension, Pulmonary; Lung; Male; Monocrotaline; Pulmonary Embolism; Pulmonary Heart Disease; Pyrroles; Pyrrolizidine Alkaloids; Rats | 1977 |
Right ventricular hypertrophy in monocrotaline pyrrole treated rats.
Topics: Animals; Blood Platelets; Blood Pressure; Capillaries; Cardiomegaly; Disease Models, Animal; Endothelium; Erythrocyte Count; Fibrin; Hematocrit; Hemoglobins; Lung; Male; Microscopy, Electron; Muscle, Smooth; Myocardium; Organ Size; Pulmonary Circulation; Pyrroles; Pyrrolizidine Alkaloids; Rats; Time Factors | 1974 |