Page last updated: 2024-08-18

pyrroles and Cardiac Remodeling, Ventricular

pyrroles has been researched along with Cardiac Remodeling, Ventricular in 45 studies

Research

Studies (45)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	10 (22.22)	29.6817
2010's	28 (62.22)	24.3611
2020's	7 (15.56)	2.80

Authors

Authors	Studies
Akar, FG; Akar, JG; Bisserier, M; Cacheux, M; Fargnoli, A; Hadri, L; Hummel, JP; Katz, MG; Obus, E; Sassi, Y; Strauss, B	1
Hanada, K; Itoh, K; Kato, T; Kawamura, Y; Kitayama, K; Kudo, N; Miura, N; Nakata, M; Narita, M; Nozaka, M; Tatara, Y; Tomita, H; Toyama, Y; Tsushima, M; Yokono, Y	1
Bikou, O; Hadri, L; Hajjar, RJ; Sassi, Y	1
Higuchi, T; Inagaki, T; Masaki, T; Nakaoka, Y; Pearson, JT; Saito, S; Schwenke, DO; Shirai, M; Tsuchimochi, H; Umetani, K	1
Kawakami, E; Miwa, H; Naito, A; Sakao, S; Sanada, TJ; Shoji, H; Suda, R; Tanabe, N; Tatsumi, K	1
Banerjee, S; Clark, VR; Fishbein, G; Hong, J; Park, JF; Razee, A; Saddic, L; Umar, S; Williams, T	1
Hossain, A; Imamura, T; Jahan, N; Kitada, K; Kobara, H; Kosaka, S; Masaki, T; Nakano, D; Nishiyama, A; Ohsaki, H; Rahman, A; Sawano, T; Sen, A	1
Fujiwara, Y; Hayashi, T; Ijiri, Y; Imano, H; Izumi, Y; Kato, R; Katsumata, T; Okada, Y; Woo, E; Yamaguchi, T; Yoshiyama, M	1
Baust, J; Chang, B; Goda, A; Goncharov, D; Goncharova, EA; Gorcsan, J; Kobir, A; Kudryashova, TV; Mora, AL; Pena, A; Ray, A; Vanderpool, R	1
Melnyk, O; Shults, NV; Suzuki, YJ; Zungu-Edmondson, M	1
Higuchi, M; Hikasa, Y; Leong, ZP; Okida, A; Yamano, Y	1
Bogaard, HJ; da Silva Gonçalves Bos, D; de Man, FS; de Raaf, MA; Dickhoff, C; Goumans, MJ; Guignabert, C; Happé, C; Herrmann, FE; Koolwijk, P; Kuiper, VP; Kurakula, K; Lodder, K; Pan, X; Rol, N; Schalij, I; Sun, XQ; Szulcek, R; Thuillet, R; Tu, L; van Nieuw Amerongen, GP; Vonk-Noordegraaf, A; Wollin, L	1
Hikasa, Y; Leong, ZP	1
Aronovitz, MJ; Baumgartner, RA; Baur, WE; Blanton, RM; Calamaras, TD; Cooper, CW; Davis, RJ; Kapur, NK; Karas, RH; Li, N; McLaughlin, AL; Qiao, X; Richards, DA; Tam, K; Wang, GR	1
Chesler, NC; Hacker, TA; Schmuck, EG; Schreier, DA; Wang, Z	1
Chrysohoou, C; Dilaveris, P; Kioufis, S; Maniatis, K; Michalea, S; Miliou, A; Oikonomou, E; Papavassiliou, AG; Siasos, G; Stefanadis, C; Tousoulis, D; Zaromitidou, M	1
Harmann, LM; Meyer, J; Petersen, M; Routhu, KV; Sonin, DL; Strande, JL; Wakatsuki, T	1
Cao, S; Fang, W; He, Y; Li, R; Li, Y; Wang, J; Xi, S; Zhang, B	1
An, Z; Dong, N; Ge, LL; He, YQ; Li, SM; Yang, G; Zhang, WQ	1
Iwao, H; Izumi, Y; Miura, K	1
Deng, Y; Guo, X; Liu, H; Shang, J; Yuan, X; Zhu, D	1
Belló-Klein, A; Lehnen, AM; Lehnen, TE; Machado, UF; Markoski, MM; Schaan, B; Tavares, AM	1
Cheng, WP; Lo, HM; Shyu, KG; Wang, BW	1
Dohi, K; Goto, I; Ito, M; Mitani, Y; Ogihara, Y; Okamoto, R; Yamada, N	1
Boerma, M; Cao, M; Joseph, J; Melnyk, SB; Moros, EG; Pavliv, O; Sharma, S; Singh, SP; Sridharan, V; Thomas, CJ	1
Cho, H; Choi, KS; Jeong, DS; Jeong, MH; Kang, JS; Kim, HJ; Lee, DI; O'Rourke, B; Pyun, JH; Solhjoo, S; Tomaselli, GF	1
Duda, M; Maczewska, J; Maczewski, M	1
Akioka, H; Anan, F; Hara, M; Iwao, T; Nakagawa, M; Saikawa, T; Takahashi, N; Teshima, Y; Yonemochi, H; Yufu, K	1
Boyle, A; Connelly, KA; Gilbert, RE; Kelly, D; Kompa, A; Krum, H; Martin, JH; Zhang, Y	1
Geng, J; Kang, W; Wang, W; Zhang, Y; Zhao, Z; Zhiming, GE	1
Beahm, C; Chen, MH; Chu, TF; Durand, JB; Force, T; Kerkela, R; Kramer, D; Vagnozzi, R; Woulfe, KC	1
Abbate, A; Bogaard, HJ; Chang, PJ; Chau, VQ; Hoke, NN; Kasper, M; Kraskauskas, D; Mizuno, S; Natarajan, R; Salloum, FN; Voelkel, NF	1
Chen, YL; Li, L; Liu, GQ; Liu, RY; Yang, PL; Zhang, JY; Zhao, XY	1
Dai, L; Wu, S	1
Bi, Q; Bolli, R; Dawn, B; Hunt, G; Peng, Y; Sanganalmath, SK; Sato, H; Shirk, G; Tang, XL; Vincent, RJ	1
Cai, A; Dai, G; Huang, Y; Kuang, J; Mai, W; Qiu, R; Song, Y	1
Doevendans, PA; Eefting, FD; Goumans, MJ; Post, MC; Post, S; Rensing, BJ; Stella, PR; van den Branden, BJ; van Es, HW; Wildbergh, TX	1
Baumann, C; Dahal, BK; Davie, N; Evans, S; Fairman, D; Ghofrani, HA; Grimminger, F; Kilty, I; Kojonazarov, B; Kosanovic, D; Luitel, H; Majewski, M; Phillips, P; Pullamsetti, SS; Schermuly, RT; Seeger, W; Sydykov, A; Tian, X; Wayman, C; Weissmann, N	1
Fan, YH; Tian, JW; Wang, SW; Xu, L; Yang, XD; Zhang, HT; Zhao, LY; Zheng, QS	1
Bahlmann, FH; Drexler, H; Engberding, N; Fuchs, M; Haller, H; Heineke, A; Hilfiker-Kleiner, D; Hornig, B; Kotlarz, D; Landmesser, U; Mueller, M; Schaefer, A; Spiekermann, S; Templin, C; Wiencke, A	1
Bailey, M; Denver, R; Krum, H; Martin, J	1
Fukunami, M; Kioka, H; Masuda, M; Mine, T; Morita, T; Node, K; Okuda, K; Tamaki, S; Tsukamoto, Y; Yamada, T	1
Hu, SJ; Kang, L	1
Ge, CJ; Hu, SJ; Kang, L	1
Chen, YD; Ge, CJ; Hu, SJ; Ji, Y; Lu, SZ; Wu, XF	1

Reviews

1 review(s) available for pyrroles and Cardiac Remodeling, Ventricular

Article	Year
Therapeutic potential of vasopressin-receptor antagonists in heart failure. Journal of pharmacological sciences, 2014, Volume: 124, Issue:1 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzamides; Benzazepines; Body Water; Clinical Trials as Topic; Disease Models, Animal; Heart Failure; Homeostasis; Humans; Hyponatremia; Morpholines; Pyrroles; Receptors, Vasopressin; Spiro Compounds; Tolvaptan; Ventricular Remodeling	2014

Article

Year

Therapeutic potential of vasopressin-receptor antagonists in heart failure.

Journal of pharmacological sciences, 2014, Volume: 124, Issue:1

Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Benzamides; Benzazepines; Body Water; Clinical Trials as Topic; Disease Models, Animal; Heart Failure; Homeostasis; Humans; Hyponatremia; Morpholines; Pyrroles; Receptors, Vasopressin; Spiro Compounds; Tolvaptan; Ventricular Remodeling

2014

Trials

4 trial(s) available for pyrroles and Cardiac Remodeling, Ventricular

Article	Year
Dose-dependent effects of short term atorvastatin treatment on arterial wall properties and on indices of left ventricular remodeling in ischemic heart failure. Atherosclerosis, 2013, Volume: 227, Issue:2 Topics: Aged; Arteries; Atorvastatin; Cholesterol, LDL; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Endothelium, Vascular; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intercellular Adhesion Molecule-1; Male; Matrix Metalloproteinase 9; Middle Aged; Myocardial Ischemia; Natriuretic Peptide, Brain; Pyrroles; Regression Analysis; Ventricular Remodeling	2013
Early atorvastatin therapy improves cardiac function in patients with acute myocardial infarction. Journal of cardiology, 2009, Volume: 53, Issue:1 Topics: Aged; Anticholesteremic Agents; Atorvastatin; Atrial Natriuretic Factor; Cholesterol; Echocardiography; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocardial Infarction; Natriuretic Peptide, Brain; Prospective Studies; Pyrroles; Stroke Volume; Triglycerides; Ventricular Remodeling	2009
Early statin treatment prior to primary PCI for acute myocardial infarction: REPERATOR, a randomized placebo-controlled pilot trial. Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2012, Nov-01, Volume: 80, Issue:5 Topics: Aged; Atorvastatin; Biomarkers; Chi-Square Distribution; Coronary Circulation; Drug Administration Schedule; Female; Hemodynamics; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Magnetic Resonance Imaging; Male; Microcirculation; Middle Aged; Myocardial Infarction; Myocardium; Netherlands; No-Reflow Phenomenon; Percutaneous Coronary Intervention; Pilot Projects; Predictive Value of Tests; Pyrroles; Time Factors; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling	2012
Synergistic effect of amlodipine and atorvastatin on blood pressure, left ventricular remodeling, and C-reactive protein in hypertensive patients with primary hypercholesterolemia. Heart and vessels, 2008, Volume: 23, Issue:2 Topics: Aged; Amlodipine; Antihypertensive Agents; Atorvastatin; Blood Pressure; C-Reactive Protein; Drug Synergism; Drug Therapy, Combination; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Hypertrophy, Left Ventricular; Lipids; Male; Middle Aged; Pyrroles; Time Factors; Treatment Outcome; Uric Acid; Ventricular Remodeling	2008

Other Studies

40 other study(ies) available for pyrroles and Cardiac Remodeling, Ventricular

Article	Year
Right predominant electrical remodeling in a pure model of pulmonary hypertension promotes reentrant arrhythmias. Heart rhythm, 2022, Volume: 19, Issue:1 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Disease Models, Animal; Hypertension, Pulmonary; Indoles; Magnetic Resonance Imaging; Male; Pneumonectomy; Pyrroles; Rats; Rats, Sprague-Dawley; Thoracotomy; Ventricular Remodeling	2022
Blockade of PAR-1 Signaling Attenuates Cardiac Hypertrophy and Fibrosis in Renin-Overexpressing Hypertensive Mice. Journal of the American Heart Association, 2020, 06-16, Volume: 9, Issue:12 Topics: Animals; Collagen Type III; Cytokines; Disease Models, Animal; Extracellular Signal-Regulated MAP Kinases; Fibroblasts; Fibrosis; HEK293 Cells; Humans; Hypertension; Hypertrophy, Left Ventricular; Inflammation Mediators; Macrophages; Male; Mice, Inbred C57BL; Mice, Transgenic; Myocardium; Pyrroles; Quinazolines; Receptor, PAR-1; Renin; Signal Transduction; Transforming Growth Factor beta1; Up-Regulation; Ventricular Function, Left; Ventricular Remodeling	2020
Induction and Characterization of Pulmonary Hypertension in Mice using the Hypoxia/SU5416 Model. Journal of visualized experiments : JoVE, 2020, 06-03, Issue:160 Topics: Animals; Cell Hypoxia; Disease Models, Animal; Fibrosis; Heart Ventricles; Humans; Hydrogen-Ion Concentration; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Mice; Pulmonary Artery; Pulmonary Circulation; Pyrroles; Vascular Endothelial Growth Factor A; Vascular Remodeling; Ventricular Remodeling	2020
Evaluation of right coronary vascular dysfunction in severe pulmonary hypertensive rats using synchrotron radiation microangiography. American journal of physiology. Heart and circulatory physiology, 2021, 03-01, Volume: 320, Issue:3 Topics: Animals; Antihypertensive Agents; Coronary Angiography; Coronary Vessels; Disease Models, Animal; Endothelin Receptor Antagonists; Endothelin-1; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Monocrotaline; Predictive Value of Tests; Pulmonary Arterial Hypertension; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Severity of Illness Index; Sulfonamides; Synchrotrons; Vasodilation; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling	2021
Metabolic remodeling in the right ventricle of rats with severe pulmonary arterial hypertension. Molecular medicine reports, 2021, Volume: 23, Issue:4 Topics: Animals; Citric Acid Cycle; Fatty Acids; Glucose; Heart Ventricles; Humans; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Oxidation-Reduction; Pulmonary Arterial Hypertension; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling	2021
Transcriptomic Analysis of Right Ventricular Remodeling in Two Rat Models of Pulmonary Hypertension: Identification and Validation of Epithelial-to-Mesenchymal Transition in Human Right Ventricular Failure. Circulation. Heart failure, 2021, Volume: 14, Issue:2 Topics: Aged; Aged, 80 and over; Angiogenesis Inhibitors; Animals; Disease Models, Animal; Epithelial-Mesenchymal Transition; Female; Gene Expression Profiling; Heart Failure; Heart Ventricles; Humans; Hypoxia; Indoles; Male; Middle Aged; Monocrotaline; Pulmonary Arterial Hypertension; Pyrroles; Rats; Real-Time Polymerase Chain Reaction; RNA-Seq; Transcriptome; Ventricular Dysfunction, Right; Ventricular Remodeling	2021
Cardioprotective Effects of a Nonsteroidal Mineralocorticoid Receptor Blocker, Esaxerenone, in Dahl Salt-Sensitive Hypertensive Rats. International journal of molecular sciences, 2021, Feb-19, Volume: 22, Issue:4 Topics: Animals; Cardiotonic Agents; Electrocardiography; Fibrosis; Hypertension; Inflammation; Male; Mineralocorticoid Receptor Antagonists; Pyrroles; Rats, Inbred Dahl; Receptors, Mineralocorticoid; Sodium Chloride, Dietary; Sulfones; Survival Analysis; Ventricular Remodeling	2021
Capillary Degeneration and Right Ventricular Remodeling Due to Hypoxic Stress with Sugen5416. Current vascular pharmacology, 2017, Volume: 15, Issue:6 Topics: Animals; Blood Pressure; Capillaries; Disease Models, Animal; Endothelial Cells; Heart Ventricles; Hypertension, Pulmonary; Hypoxia; In Situ Nick-End Labeling; Indoles; Male; MAP Kinase Signaling System; Myocardium; Myocytes, Cardiac; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Vascular Endothelial Growth Factor; RNA, Messenger; Ventricular Remodeling	2017
Pharmacological Inhibition of mTOR Kinase Reverses Right Ventricle Remodeling and Improves Right Ventricle Structure and Function in Rats. American journal of respiratory cell and molecular biology, 2017, Volume: 57, Issue:5 Topics: Animals; Cell Proliferation; Cell Survival; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Myocytes, Cardiac; Protein Kinase Inhibitors; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; TOR Serine-Threonine Kinases; Ventricular Remodeling	2017
Natural reversal of pulmonary vascular remodeling and right ventricular remodeling in SU5416/hypoxia-treated Sprague-Dawley rats. PloS one, 2017, Volume: 12, Issue:8 Topics: Animals; Blotting, Western; Fibrosis; Heart Ventricles; Hemodynamics; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Lung; Male; Metabolomics; Pulmonary Artery; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling	2017
Reversal effects of low-dose imatinib compared with sunitinib on monocrotaline-induced pulmonary and right ventricular remodeling in rats. Vascular pharmacology, 2018, Volume: 100 Topics: Animals; Disease Models, Animal; Dose-Response Relationship, Drug; Extracellular Signal-Regulated MAP Kinases; Gene Expression Regulation; Heart Ventricles; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Imatinib Mesylate; Indoles; Male; Monocrotaline; Nestin; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-raf; Pulmonary Artery; Pyrroles; Rats, Wistar; Receptor, Fibroblast Growth Factor, Type 1; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling	2018
Nintedanib improves cardiac fibrosis but leaves pulmonary vascular remodelling unaltered in experimental pulmonary hypertension. Cardiovascular research, 2019, 02-01, Volume: 115, Issue:2 Topics: Adult; Animals; Cell Proliferation; Cells, Cultured; Disease Models, Animal; Endothelial Cells; Extracellular Matrix; Female; Fibroblasts; Fibrosis; Humans; Indoles; Male; Myocardium; Protein Kinase Inhibitors; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling; Young Adult	2019
Effects of toceranib compared with sorafenib on monocrotaline-induced pulmonary arterial hypertension and cardiopulmonary remodeling in rats. Vascular pharmacology, 2018, Volume: 110 Topics: Animals; Antihypertensive Agents; Arterial Pressure; Autophagy; Disease Models, Animal; Dose-Response Relationship, Drug; Humans; Hypertension, Pulmonary; Hypertrophy, Right Ventricular; Indoles; Male; Monocrotaline; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pulmonary Artery; Pyrroles; Rats, Wistar; Signal Transduction; Sorafenib; Vascular Remodeling; Ventricular Function, Right; Ventricular Remodeling	2018
Mixed lineage kinase-3 prevents cardiac dysfunction and structural remodeling with pressure overload. American journal of physiology. Heart and circulatory physiology, 2019, 01-01, Volume: 316, Issue:1 Topics: Animals; Cardiac Output; Cardiomegaly; Cells, Cultured; Humans; Male; MAP Kinase Kinase 4; MAP Kinase Kinase Kinases; MAP Kinase Signaling System; Mice; Mice, Inbred C57BL; Mitogen-Activated Protein Kinase Kinase Kinase 11; Myocytes, Cardiac; Protein Kinase Inhibitors; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling	2019
Beneficial effects of mesenchymal stem cell delivery via a novel cardiac bioscaffold on right ventricles of pulmonary arterial hypertensive rats. American journal of physiology. Heart and circulatory physiology, 2019, 05-01, Volume: 316, Issue:5 Topics: Animals; Arterial Pressure; Cells, Cultured; Disease Models, Animal; Fibrosis; Hypertrophy, Right Ventricular; Hypoxia; Indoles; Male; Mesenchymal Stem Cell Transplantation; Myocardial Contraction; Myocardium; Pulmonary Arterial Hypertension; Pulmonary Artery; Pyrroles; Rats, Sprague-Dawley; Recovery of Function; Regeneration; Tissue Scaffolds; Ventricular Dysfunction, Right; Ventricular Function, Right; Ventricular Remodeling; von Willebrand Factor	2019
Protease-activated receptor 1 inhibition by SCH79797 attenuates left ventricular remodeling and profibrotic activities of cardiac fibroblasts. Journal of cardiovascular pharmacology and therapeutics, 2013, Volume: 18, Issue:5 Topics: Animals; Disease Models, Animal; Fibroblasts; Fibrosis; Imaging, Three-Dimensional; Male; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Myocardial Infarction; Myocardial Reperfusion Injury; Phosphorylation; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Transforming Growth Factor beta; Ventricular Remodeling	2013
Differential expression of Nad(P)H oxidase isoforms and the effects of atorvastatin on cardiac remodeling in two-kidney two-clip hypertensive rats. Die Pharmazie, 2013, Volume: 68, Issue:4 Topics: Animals; Atorvastatin; Atrial Natriuretic Factor; Blotting, Western; Fibrosis; Hemodynamics; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension, Renovascular; Isoenzymes; Male; Membrane Glycoproteins; Myocardium; Myosin Heavy Chains; NADPH Oxidase 2; NADPH Oxidase 4; NADPH Oxidases; Pyrroles; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Ventricular Dysfunction, Left; Ventricular Function, Left; Ventricular Remodeling	2013
Atorvastatin reduces myocardial fibrosis in a rat model with post-myocardial infarction heart failure by increasing the matrix metalloproteinase-2/tissue matrix metalloproteinase inhibitor-2 ratio. Chinese medical journal, 2013, Volume: 126, Issue:11 Topics: Animals; Atorvastatin; Collagen; Disease Models, Animal; Female; Fibrosis; Heart Failure; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Matrix Metalloproteinase 2; Myocardial Infarction; Myocardium; Pyrroles; Rats; Rats, Wistar; Tissue Inhibitor of Metalloproteinase-2; Ventricular Remodeling	2013
Atorvastatin attenuates myocardial remodeling induced by chronic intermittent hypoxia in rats: partly involvement of TLR-4/MYD88 pathway. Biochemical and biophysical research communications, 2014, Mar-28, Volume: 446, Issue:1 Topics: Animals; Atorvastatin; Cardiomegaly; Cytokines; Heart; Heptanoic Acids; Hypoxia; Male; Myeloid Differentiation Factor 88; Myocardium; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Reactive Oxygen Species; RNA, Messenger; Signal Transduction; Sleep Apnea, Obstructive; Toll-Like Receptor 4; Ventricular Remodeling	2014
Atorvastatin administered before myocardial infarction in rats improves contractility irrespective of metabolic changes. Clinical and experimental pharmacology & physiology, 2014, Volume: 41, Issue:12 Topics: Animals; Atorvastatin; Echocardiography; Glucose Transporter Type 4; Heart Ventricles; Heptanoic Acids; Male; Muscle Contraction; Myocardial Infarction; Myocardium; Pyrroles; Rats; Rats, Inbred WKY; Ventricular Remodeling	2014
MicroRNA-208a Increases Myocardial Endoglin Expression and Myocardial Fibrosis in Acute Myocardial Infarction. The Canadian journal of cardiology, 2015, Volume: 31, Issue:5 Topics: Animals; Atorvastatin; Blotting, Western; Cells, Cultured; Disease Models, Animal; Endoglin; Fibrosis; Gene Expression Regulation; Hemodynamics; Heptanoic Acids; Immunohistochemistry; Intracellular Signaling Peptides and Proteins; Male; MicroRNAs; Muscle Cells; Myocardial Infarction; Polymerase Chain Reaction; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Sensitivity and Specificity; Tetrazoles; Valine; Valsartan; Ventricular Remodeling	2015
Detrimental Impact of Vasopressin V2 Receptor Antagonism in a SU5416/Hypoxia/Normoxia-Exposed Rat Model of Pulmonary Arterial Hypertension. Circulation journal : official journal of the Japanese Circulation Society, 2016, Volume: 80, Issue:4 Topics: Animals; Antidiuretic Hormone Receptor Antagonists; Disease Models, Animal; Hypertension, Pulmonary; Hypoxia; Indoles; Male; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Vasopressin; Up-Regulation; Ventricular Remodeling	2016
Effects of local irradiation combined with sunitinib on early remodeling, mitochondria, and oxidative stress in the rat heart. Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2016, Volume: 119, Issue:2 Topics: Animals; Cell Death; Heart; Indoles; Male; Mitochondria, Heart; Mitochondrial Membrane Transport Proteins; Mitochondrial Permeability Transition Pore; Oxidative Stress; Pyrroles; Rats; Rats, Sprague-Dawley; Sunitinib; Ventricular Remodeling	2016
Cdon deficiency causes cardiac remodeling through hyperactivation of WNT/β-catenin signaling. Proceedings of the National Academy of Sciences of the United States of America, 2017, 02-21, Volume: 114, Issue:8 Topics: Animals; beta Catenin; Cell Adhesion Molecules; Connexin 43; Connexins; Fibrosis; Gap Junctions; Heart; Mice; Mice, Inbred C57BL; Myocardium; Myocytes, Cardiac; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Up-Regulation; Ventricular Remodeling; Wnt Signaling Pathway	2017
Hypercholesterolaemia exacerbates ventricular remodelling after myocardial infarction in the rat: role of angiotensin II type 1 receptors. British journal of pharmacology, 2008, Volume: 154, Issue:8 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anticholesteremic Agents; Atorvastatin; Drug Therapy, Combination; Echocardiography; Heptanoic Acids; Hypercholesterolemia; Losartan; Male; Myocardial Infarction; Pyrroles; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Up-Regulation; Ventricular Dysfunction, Left; Ventricular Remodeling	2008
Effect of atorvastatin on cardiac remodelling and mortality in rats following hyperglycemia and myocardial infarction. International journal of cardiology, 2010, Sep-03, Volume: 143, Issue:3 Topics: Animals; Atorvastatin; Body Weight; Cardiac Volume; Collagen Type I; Collagen Type III; Diabetes Mellitus, Experimental; Disease Models, Animal; Female; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperglycemia; Myocardial Infarction; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling	2010
Atorvastatin reverses cardiac remodeling possibly through regulation of protein kinase D/myocyte enhancer factor 2D activation in spontaneously hypertensive rats. Pharmacological research, 2010, Volume: 61, Issue:1 Topics: Animals; Atorvastatin; Blood Pressure; Disease Models, Animal; Enzyme Activation; Fibrosis; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Hypertension; Hypertrophy, Left Ventricular; Lipids; Male; MEF2 Transcription Factors; Myocardium; Protein Kinase C; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Signal Transduction; Time Factors; Transcription Factors; Ventricular Remodeling	2010
Sunitinib-induced cardiotoxicity is mediated by off-target inhibition of AMP-activated protein kinase. Clinical and translational science, 2009, Volume: 2, Issue:1 Topics: AMP-Activated Protein Kinases; Animals; Biopsy; Capillaries; Cell Survival; Echocardiography; Humans; Indoles; Inhibitory Concentration 50; Mechanistic Target of Rapamycin Complex 1; Membrane Potential, Mitochondrial; Mice; Mice, Inbred C57BL; Mitochondria; Multiprotein Complexes; Myocardium; Myocytes, Cardiac; Protein Kinase Inhibitors; Proteins; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Sunitinib; TOR Serine-Threonine Kinases; Transcription Factors; Ventricular Remodeling	2009
Adrenergic receptor blockade reverses right heart remodeling and dysfunction in pulmonary hypertensive rats. American journal of respiratory and critical care medicine, 2010, Sep-01, Volume: 182, Issue:5 Topics: Adrenergic Antagonists; Animals; Carbazoles; Carvedilol; Disease Models, Animal; Hypertension, Pulmonary; Indoles; Male; Propanolamines; Pulmonary Circulation; Pyrroles; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Ventricular Dysfunction, Right; Ventricular Remodeling	2010
Atorvastatin prevents left ventricular remodeling in spontaneously hypertensive rats. International heart journal, 2010, Volume: 51, Issue:6 Topics: Animals; Atorvastatin; Connective Tissue Growth Factor; Gene Expression; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Pyrroles; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Remodeling	2010
[Atorvastatin attenuates hypoxic pulmonary hypertension in rats by inhibiting RhoA/Rho kinase pathway]. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2011, Volume: 36, Issue:1 Topics: Animals; Anticholesteremic Agents; Atorvastatin; Hemodynamics; Heptanoic Acids; Hypertension, Pulmonary; Hypoxia; Male; Pulmonary Artery; Pyrroles; Random Allocation; Rats; Rats, Wistar; rho-Associated Kinases; rhoA GTP-Binding Protein; Signal Transduction; Ventricular Remodeling	2011
Atorvastatin therapy during the peri-infarct period attenuates left ventricular dysfunction and remodeling after myocardial infarction. PloS one, 2011, Volume: 6, Issue:9 Topics: Animals; Apoptosis; Atorvastatin; Female; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hydroxyproline; Muscle Contraction; Myocardial Infarction; Myocytes, Cardiac; Pyrroles; Rats; Rats, Inbred F344; Ventricular Dysfunction, Left; Ventricular Remodeling	2011
[Effect of atorvastatin on cardiac function and TGF-β1 signaling pathway after acute myocardial infarction in rats]. Nan fang yi ke da xue xue bao = Journal of Southern Medical University, 2012, Volume: 32, Issue:2 Topics: Animals; Atorvastatin; Heart; Heptanoic Acids; Male; Myocardial Infarction; Pyrroles; Rats; Rats, Sprague-Dawley; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta1; Ventricular Remodeling	2012
Effects of multikinase inhibitors on pressure overload-induced right ventricular remodeling. International journal of cardiology, 2013, Sep-10, Volume: 167, Issue:6 Topics: Animals; Dose-Response Relationship, Drug; Familial Primary Pulmonary Hypertension; Hypertension, Pulmonary; Indoles; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley; Sorafenib; Sunitinib; Ventricular Function, Right; Ventricular Remodeling	2013
[Effects of atorvastatin on the proliferation and collagen synthesis of rat cardiac fibroblasts]. Zhonghua yi xue za zhi, 2003, Jan-25, Volume: 83, Issue:2 Topics: Animals; Animals, Newborn; Atorvastatin; Cell Division; Cells, Cultured; Collagen; Fibroblasts; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Myocardium; Pyrroles; Rats; Rats, Sprague-Dawley; Ventricular Remodeling	2003
Statin-induced improvement of endothelial progenitor cell mobilization, myocardial neovascularization, left ventricular function, and survival after experimental myocardial infarction requires endothelial nitric oxide synthase. Circulation, 2004, Oct-05, Volume: 110, Issue:14 Topics: Animals; Atorvastatin; Biological Availability; Capillaries; Cells, Cultured; Collateral Circulation; Drug Resistance; Endothelial Cells; Fibrosis; Heart Failure; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mesenchymal Stem Cells; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardial Infarction; Myocardium; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Pyrroles; Random Allocation; Ultrasonography; Vasodilation; Ventricular Function, Left; Ventricular Remodeling	2004
In vitro inhibitory effects of atorvastatin on cardiac fibroblasts: implications for ventricular remodelling. Clinical and experimental pharmacology & physiology, 2005, Volume: 32, Issue:9 Topics: Angiotensin II; Animals; Atorvastatin; Cells, Cultured; Collagen; Connective Tissue Growth Factor; Dose-Response Relationship, Drug; Extracellular Matrix; Fibroblasts; Heart; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Myocardium; Procollagen; Pyrroles; Rats; Transforming Growth Factor beta; Transforming Growth Factor beta1; Ventricular Remodeling	2005
Atorvastatin therapy associated with improvement in left ventricular remodeling in a case of idiopathic dilated cardiomyopathy. The American journal of the medical sciences, 2006, Volume: 332, Issue:6 Topics: Adult; Anticholesteremic Agents; Atorvastatin; Cardiomyopathy, Dilated; Cardiovascular Agents; Heptanoic Acids; Humans; Hypercholesterolemia; Male; Pyrroles; Ventricular Remodeling	2006
[Effect of atorvastatin on left ventricular remodeling in spontaneously hypertensive rats]. Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2007, Volume: 36, Issue:1 Topics: Animals; Anticholesteremic Agents; Apoptosis; Atorvastatin; Blood Pressure; Heptanoic Acids; Hydroxyproline; Hypertension; Lipids; Male; Myocardium; Proliferating Cell Nuclear Antigen; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Up-Regulation; Ventricular Remodeling	2007
Beneficial effect of atorvastatin on left ventricular remodeling in spontaneously hypertensive rats. Pharmacology, 2007, Volume: 80, Issue:2-3 Topics: Animals; Apoptosis; Atorvastatin; Blood Pressure; Cardiomegaly; Collagen; Cyclin-Dependent Kinase Inhibitor p27; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lipids; Male; Myocardium; Pyrroles; Random Allocation; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Ventricular Remodeling	2007