Page last updated: 2024-08-18

pyrroles and Canine Diseases

pyrroles has been researched along with Canine Diseases in 75 studies

Research

Studies (75)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	6 (8.00)	29.6817
2010's	44 (58.67)	24.3611
2020's	25 (33.33)	2.80

Authors

Authors	Studies
Breitbach, JT; Fenger, JM; Geisler, JA; Husbands, BD; Korec, DI; Louke, DS	1
Brawner, W; Ehling, TJ; Farrelly, J; Fidel, J; Green, E; Haney, S; Klein, MK; LaDue, T; Looper, J; Prescott, D; Saba, C; Shiomitsu, K; Smith, L; Turek, M	1
Langova, V; Nguyen, SM; Thomas, PM; Todd, JE; Tzannes, S; White, J	1
Frezoulis, P; Harper, A	1
Marycz, K; Serwotka-Suszczak, A; Sobierajska, P; Szymanski, D; Targonska, S; Wiglusz, RJ	1
Goto, S; Iwasaki, R; Maeda, A; Mori, T; Murakami, M; Sakai, H; Yamada, K	1
Barber, LG; Keyerleber, MA	1
Gregory, J; Hocker, S; Thomason, J	1
Gedon, J; Kessler, M; Schmidt, JM	1
Kim, E; Kim, SS; Ryu, MO	1
Blackwood, L; Harper, A; Mason, S	1
Fernandes, AFA; Heaton, CM; Jark, PC; Pan, X	1
Bello, NM; Biller, B; Hocker, S; Sheppard-Olivares, S; Szivek, A; Wood, E; Wouda, RM	1
Hanazono, K; Hoshino, Y; Hosoya, K; Izumi, Y; Takagi, S; Yamazaki, H	1
Akiyoshi, H; Mie, K; Miura, N; Nishida, H; Tanaka, T; Yamazaki, H	1
Bottiglieri, A; Ciani, F; Comite, E; De Filippis, A; De Martino, L; Gioia, L; Lorito, M; Nocera, FP; Staropoli, A; Tafuri, S; Vinale, F; Woo, SL	1
Bonkobara, M; Kurita, S; Michishita, M; Miyamoto, R; Nagashima, T; Noguchi, S; Tamura, K; Tani, H; Yayoshi, N	1
Donnelly, LL; Herrera, CL; Remerowski, SM	1
Alonso-Miguel, D; Clarés Moral, I; García-San José, P; González Sanz, S; Pérez-Alenza, MD	1
Borrego, JF; Clemente-Vicario, F; Hernández, A; Merino-Gutierrez, V; Puig, J	1
Boss, MK; LaRue, SM; Leary, D; Martin, T; Prebble, AR; Thamm, DH; Weishaar, KM	1
Johannes, CM; Musser, ML	1
Alonso-Diez, Á; Alonso-Miguel, D; Clares, I; García-San José, P; Peña, L; Pérez-Alenza, MD; Portero, M; Valdivia, G	1
Fukazawa, E; Harada, K; Ichimata, M; Kagawa, Y; Katayama, R; Kobayashi, T; Matsuyama, F; Nishiyama, S; Toshima, A; Yamagami, T	1
Endo, Y; Goto-Koshino, Y; Lai, YC; Miura, N; Nakaichi, M; Setoguchi, A; Takahashi, M; Tsujimoto, H; Yamazaki, H; Yasuyuki, M	1
Biller, BJ; Coy, J; Laver, T; London, CA; Thamm, DH; Vail, DM	1
Argyle, DJ; Bavcar, S; Buracco, P; de Fornel, P; de Vos, J; Hirschberger, J; Kessler, M; Murphy, S	1
Clarke, D; Gieger, TL; Hallman, B; Johannes, C; Nettifee-Osborne, J; Nolan, MW; Williams, LE	1
Higginbotham, ML; Hocker, SE; Wouda, RM	1
Kim, C; Matsuyama, A; Mutsaers, AJ; Woods, JP	1
Balkman, CE; Cawley, JR; Hume, KR; Rizzo, VL	1
Avery, AC; Charles, JB; Clifford, CA; Ehrhart, EJ; Eickhoff, JC; Elmslie, RE; London, CA; Thamm, DH; Vail, DM; Weishaar, KM	1
Biasato, I; Buracco, P; De Maria, R; Gattino, F; Gola, C; Iussich, S; Maniscalco, L; Martano, M; Martín de Las Mulas, J; Millán Ruiz, Y; Morello, E; Saeki, N	1
Banovic, F; Blubaugh, A; Denley, T; Eguiluz-Hernandez, S; Elder, D; Rissi, D	1
Eom, K; Kim, JH; Sung, HJ; Yoon, H; Yoon, HY	1
Marconato, L; Rossi, F; Sabattini, S; Vascellari, M	1
Balkman, CE; Hume, KR; Piscoya, SL	1
Bergman, PJ; Johannes, CM; Musser, ML; Taikowski, KL	1
Allenspach, K; Berger, EP; Du, Y; Fox, LE; Jergens, AE; Johannes, CM; Mochel, JP; Musser, ML; Powers, BE	1
Ballash, G; Fenger, J; Kovac, RL; London, C; Warry, E	1
Elliott, JW	1
Iguchi, A; Kobayashi, S; Mitsui, I; Ooshida, J; Satou, R; Uchida, N; Yamasaki, M	1
Jackson, AE	1
Best, MP; Boyd, SP; Danesi, P	1
Borrego, J; Burgess, KE; Cunningham, S; Lew, FH; McQuown, B	1
Cámara-Fernández, N; Cartagena-Albertus, JC; Moise, A; Montoya-Alonso, JA; Moya-García, S	1
Charles, JB; Ehrhart, EJ; Thamm, DH; Weishaar, KM	1
Brearley, M; Dobson, J; Marcinowska, A; Warland, J	1
Breen, M; Culver, S; Dunbar, M; Kow, K; Milner, RJ; Owen, JL; Pérez, ML	1
Bernabe, LF; Kisseberth, WC; London, CA; Nguyen, S; Pennell, M; Portela, R; Yancey, MF	1
Kurzman, ID; Pan, X; Tsimbas, K; Vail, DM	1
London, CA	1
Bailey, DB; Borgatti, A; Clifford, CA; Crawford-Jakubiak, M; Cronin, KL; Gardner, HL; Gill, VL; Henry, CJ; Klein, MK; Locke, J; London, CA; Mathie, T; Northrup, NC; Pennell, ML; Phillips, B; Portela, R; Post, G; Rosenberg, MP; Ruslander, DM; Stingle, N; Thamm, DH; Vail, DM; Williams, LE; Wilson-Robles, H	1
Bergman, P; Clifford, C; Crawford-Jakubiak, M; Gardner, HL; Garrett, LD; Henry, C; Klein, MK; Locke, J; London, CA; Nguyen, S; Portela, RA; Rosenberg, MP; Thamm, DH; Vail, DM	1
Baines, SJ; Hartley, JA; Mellinas-Gomez, M; Paredes-Moscosso, SR; Pedley, RB; Robson, M; Spanswick, VJ; Stell, A; Thurston, DE	1
Biller, BJ; Kurzman, ID; Pellin, MA; Robinson, K; Tsimbas, K; Vail, DM; Wouda, RM	1
Markovic, LE; Stein, TJ; Stepien, RL; Tjostheim, SS	1
Chew, DJ; Drost, WT; Gardner, HL; Green, EM; Hostnik, ET; London, CA; Nguyen, SM; Peng, J; Portela, RA; Rippy, SB; Warry, EE	1
Barnes, K; Cavalcanti, JVJ; Dange, RB; Hasbach, A; Patterson, J; Saavedra, PV	1
Baines, L; Elliott, JW; Parry, A; Swinbourne, F	1
Gordon, I; Khanna, C	1
Bergman, PJ; Boucher, JF; Couto, GC; Henry, CJ; Hintermeister, JG; Klein, MK; London, CA; Malpas, PB; Mauldin, GN; Michels, GM; Mitchener, KL; Rosenberg, MP; Rusk, AW; Wood-Follis, SL	1
Huelsmeyer, MK; Kurzman, ID; Mitzey, AM; Qurollo, B; Rose, BJ; Thamm, DH	1
Kupfer, J	1
Boucher, JF; Lesman, SP; Merritt, DA; Michels, GM; Yancey, MF	1
Al-Sarraf, R; Johnson, CS; Malone, EK; Rassnick, KM; Ruslander, DM; Russell, DS; Trump, DL; Wakshlag, JJ	1
Bunting, L; Kurzman, I; London, C; McCartan, L; Robat, C; Selting, K; Stingle, N; Vail, DM	1
Chon, E; Kubicek, LN; McCartan, L; Vail, DM	1
de Vos, J; de Vos, P; Noorman, E; Ramos Vega, S	1
Alvarez, F; Beaver, L; Bryan, J; Carreras, J; Clifford, C; Ettinger, S; Fulton, L; Gauthier, M; Gill, V; Gillings, S; Haney, S; Henry, C; Hershey, B; Higginbotham, ML; Hillman, L; Jones, P; Kiselow, M; Klein, MK; Krick, E; Ladue, T; London, C; Mathie, T; McNeill, C; Novasad, A; Phillips, B; Stingle, N; Thamm, D; Vail, DM; Vaughan, A; Vickery, K	1
Kisseberth, WC; London, CA; Russell, DS; Urie, BK	1
Boucher, J; Cherrington, JM; Chien, MB; Downing, S; Hannah, AL; Kollias-Baker, C; London, CA; McMahon, G; Mendel, DB; Post, G; Rosenberg, M; Shenoy, N; Zadovoskaya, R	1
Cherrington, JM; Lee, LB; London, CA; Pryer, NK; Sukbuntherng, J; Yu, X; Zadovaskaya, R	1
Doucet, M; Lussier, B; Martel-Pelletier, J; Moreau, M; Pelletier, JP; Vincent, G	1

Reviews

2 review(s) available for pyrroles and Canine Diseases

Article	Year
The role of toceranib phosphate in dogs with non-mast cell neoplasia: A systematic review. Veterinary and comparative oncology, 2022, Volume: 20, Issue:2 Topics: Animals; Antineoplastic Agents; Bone Neoplasms; Dog Diseases; Dogs; Humans; Indoles; Osteosarcoma; Pyrroles	2022
Small molecule inhibitors in veterinary oncology practice. The Veterinary clinics of North America. Small animal practice, 2014, Volume: 44, Issue:5 Topics: Animals; Benzamides; Cat Diseases; Cats; Dog Diseases; Dogs; Indoles; Neoplasms; Piperidines; Protein Kinase Inhibitors; Pyridines; Pyrroles; Thiazoles	2014

Trials

13 trial(s) available for pyrroles and Canine Diseases

Article	Year
The impact of carboplatin and toceranib phosphate on serum vascular endothelial growth factor (VEGF) and metalloproteinase-9 (MMP-9) levels and survival in canine osteosarcoma. Canadian journal of veterinary research = Revue canadienne de recherche veterinaire, 2017, Volume: 81, Issue:3 Topics: Amputation, Surgical; Animals; Antineoplastic Agents; Carboplatin; Chemotherapy, Adjuvant; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Gene Expression Regulation, Neoplastic; Indoles; Male; Matrix Metalloproteinase 9; Osteosarcoma; Pilot Projects; Pyrroles; Vascular Endothelial Growth Factor A	2017
Safety evaluation of combination carboplatin and toceranib phosphate (Palladia) in tumour-bearing dogs: A phase I dose finding study. Veterinary and comparative oncology, 2018, Volume: 16, Issue:1 Topics: Animals; Carboplatin; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Indoles; Male; Neoplasms; Pyrroles	2018
c-Kit Mutation and Localization Status as Response Predictors in Mast Cell Tumors in Dogs Treated with Prednisone and Toceranib or Vinblastine. Journal of veterinary internal medicine, 2018, Volume: 32, Issue:1 Topics: Animals; Antineoplastic Agents; Disease-Free Survival; Dog Diseases; Dogs; Female; Indoles; Male; Mastocytosis, Cutaneous; Mutation; Prednisone; Prospective Studies; Proto-Oncogene Proteins c-kit; Pyrroles; Vinblastine	2018
Phosphorylated KIT as a predictor of outcome in canine mast cell tumours treated with toceranib phosphate or vinblastine. Veterinary and comparative oncology, 2020, Volume: 18, Issue:2 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Gene Expression Regulation, Neoplastic; Indoles; Mast-Cell Sarcoma; Phosphorylation; Prospective Studies; Proto-Oncogene Proteins c-kit; Pyrroles; Skin Neoplasms; Vinblastine	2020
Safety evaluation of combination CCNU and continuous toceranib phosphate (Palladia(®) ) in tumour-bearing dogs: a phase I dose-finding study. Veterinary and comparative oncology, 2016, Volume: 14, Issue:2 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Combinations; Indoles; Lomustine; Neoplasms; Pyrroles	2016
Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study. PloS one, 2015, Volume: 10, Issue:4 Topics: Administration, Metronomic; Amputation, Surgical; Animals; Bone Neoplasms; Carboplatin; Cyclophosphamide; Diarrhea; Disease-Free Survival; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Indoles; Kaplan-Meier Estimate; Male; Neutropenia; Osteosarcoma; Piroxicam; Prospective Studies; Pyrroles; Regression Analysis; Treatment Outcome	2015
Safety evaluation of combination doxorubicin and toceranib phosphate (Palladia®) in tumour bearing dogs: a phase I dose-finding study. Veterinary and comparative oncology, 2017, Volume: 15, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Agents; Dog Diseases; Dogs; Doxorubicin; Drug Administration Schedule; Drug Therapy, Combination; Female; Flow Cytometry; Indoles; Male; Neoplasms; Neutropenia; Pyrroles	2017
Pharmacokinetic properties of toceranib phosphate (Palladia, SU11654), a novel tyrosine kinase inhibitor, in laboratory dogs and dogs with mast cell tumors. Journal of veterinary pharmacology and therapeutics, 2010, Volume: 33, Issue:2 Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Cross-Over Studies; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Fasting; Female; Half-Life; Indoles; Injections, Intravenous; Male; Mastocytosis, Cutaneous; Molecular Structure; Protein-Tyrosine Kinases; Pyrroles	2010
Calcitriol (1,25-dihydroxycholecalciferol) enhances mast cell tumour chemotherapy and receptor tyrosine kinase inhibitor activity in vitro and has single-agent activity against spontaneously occurring canine mast cell tumours. Veterinary and comparative oncology, 2010, Volume: 8, Issue:3 Topics: Animals; Antineoplastic Agents; Benzamides; Blotting, Western; Calcitriol; Calcium Channel Agonists; Cell Line, Tumor; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Female; Imatinib Mesylate; Indoles; Lomustine; Male; Mastocytoma; Piperazines; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptors, Calcitriol; Skin Neoplasms; Treatment Outcome; Vinblastine	2010
Safety evaluation of combination vinblastine and toceranib phosphate (Palladia®) in dogs: a phase I dose-finding study. Veterinary and comparative oncology, 2012, Volume: 10, Issue:3 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Indoles; Male; Mastocytosis; Protein-Tyrosine Kinases; Pyrroles; Skin Neoplasms; Vinblastine	2012
Safety evaluation of combination toceranib phosphate (Palladia®) and piroxicam in tumour-bearing dogs (excluding mast cell tumours): a phase I dose-finding study. Veterinary and comparative oncology, 2012, Volume: 10, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Gastrointestinal Diseases; Indoles; Male; Neoplasms; Piroxicam; Protein-Tyrosine Kinases; Pyrroles	2012
Phase I dose-escalating study of SU11654, a small molecule receptor tyrosine kinase inhibitor, in dogs with spontaneous malignancies. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Volume: 9, Issue:7 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Indoles; Inhibitory Concentration 50; Male; Models, Chemical; Mutation; Neoplasms; Proto-Oncogene Proteins c-kit; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Vascular Endothelial Growth Factor; Time Factors; Tomography, X-Ray Computed	2003
Efficacy of licofelone in dogs with clinical osteoarthritis. The Veterinary record, 2007, Apr-28, Volume: 160, Issue:17 Topics: Acetates; Animals; Anti-Inflammatory Agents, Non-Steroidal; Dog Diseases; Dogs; Double-Blind Method; Female; Gait; Lameness, Animal; Male; Osteoarthritis; Pyrroles	2007

Other Studies

60 other study(ies) available for pyrroles and Canine Diseases

Article	Year
Characterization of receptor tyrosine kinase activation and biological activity of toceranib phosphate in canine urothelial carcinoma cell lines. BMC veterinary research, 2021, Oct-02, Volume: 17, Issue:1 Topics: Animals; Carcinoma, Transitional Cell; Cell Line, Tumor; Cell Proliferation; Dog Diseases; Dogs; Female; Indoles; Male; Pyrroles; Receptor Protein-Tyrosine Kinases; Urinary Bladder Neoplasms	2021
A prospective, multi-centre, Veterinary Radiation Therapy Oncology Group study reveals potential efficacy of toceranib phosphate (Palladia) as a primary or adjuvant agent in the treatment of canine nasal carcinoma. Veterinary and comparative oncology, 2022, Volume: 20, Issue:1 Topics: Animals; Antineoplastic Agents; Carcinoma; Dog Diseases; Dogs; Indoles; Nose Neoplasms; Prospective Studies; Pyrroles	2022
Combination vinblastine and palladia for high-grade and metastatic mast cell tumors in dogs. The Canadian veterinary journal = La revue veterinaire canadienne, 2021, Volume: 62, Issue:12 Topics: Animals; Dog Diseases; Dogs; Indoles; Mast Cells; Neoplasms; Pyrroles; Retrospective Studies; Vinblastine	2021
Synergistic Effect of Toceranib and Nanohydroxyapatite as a Drug Delivery Platform-Physicochemical Properties and In Vitro Studies on Mastocytoma Cells. International journal of molecular sciences, 2022, Feb-09, Volume: 23, Issue:4 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dog Diseases; Dogs; Drug Carriers; Drug Delivery Systems; Drug Synergism; Durapatite; Indoles; Mastocytoma; Nanoparticles; Protein Kinase Inhibitors; Pyrroles	2022
Outcome of Localized Bile Duct Carcinoma in Six Dogs Treated with Liver Lobectomy. Journal of the American Animal Hospital Association, 2022, Jul-01, Volume: 58, Issue:4 Topics: Animals; Bile Ducts; Carcinoma; Dog Diseases; Dogs; Liver; Pyrroles	2022
Pilot study evaluating the tolerability of a 3 Gy × 10 daily fraction 3D-conformal palliative radiation therapy protocol plus toceranib for the treatment of measurable carcinomas in the dog. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association, 2022, Volume: 63, Issue:6 Topics: Animals; Carcinoma; Dog Diseases; Dogs; Pilot Projects; Prospective Studies; Pyrroles; Quality of Life; Radiotherapy, Conformal	2022
Toceranib phosphate resolves right heart obstruction secondary to a heart base neoplasm in a dog. Journal of veterinary cardiology : the official journal of the European Society of Veterinary Cardiology, 2022, Volume: 44 Topics: Animals; Dog Diseases; Dogs; Heart Block; Heart Failure; Heart Neoplasms; Male; Pyrroles	2022
Frontal sinus carcinoma in forty-one dogs (2001-2022). Veterinary and comparative oncology, 2023, Volume: 21, Issue:2 Topics: Animals; Carcinoma, Squamous Cell; Dog Diseases; Dogs; Female; Frontal Sinus; Male; Meloxicam; Mouth Neoplasms; Paranasal Sinus Neoplasms; Pyrroles; Retrospective Studies	2023
Palmar-plantar erythrodysesthesia syndrome resulting from toceranib phosphate in a dog with apocrine gland anal sac adenocarcinoma: a case report. Journal of veterinary science, 2023, Volume: 24, Issue:6 Topics: Adenocarcinoma; Anal Sacs; Animals; Apocrine Glands; Dog Diseases; Dogs; Male; Pyrroles	2023
Investigation of thyroid function in dogs treated with the tyrosine kinase inhibitor toceranib. Veterinary and comparative oncology, 2020, Volume: 18, Issue:3 Topics: Animals; Dog Diseases; Dogs; Female; Hypothyroidism; Indoles; Male; Neoplasms; Prospective Studies; Pyrroles; Thyroid Gland; Thyrotropin; Thyroxine; United Kingdom	2020
Evaluation of toceranib for treatment of apocrine gland anal sac adenocarcinoma in dogs. Journal of veterinary internal medicine, 2020, Volume: 34, Issue:2 Topics: Adenocarcinoma; Anal Gland Neoplasms; Anal Sacs; Animals; Apocrine Glands; Disease-Free Survival; Dog Diseases; Dogs; Female; Indoles; Male; Pyrroles; Retrospective Studies; Treatment Outcome; Wisconsin	2020
Toceranib phosphate in the treatment of canine thyroid carcinoma: 42 cases (2009-2018). Veterinary and comparative oncology, 2020, Volume: 18, Issue:4 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Indoles; Pyrroles; Survival; Thyroid Neoplasms	2020
Assessment of tumor enhancement by contrast-enhanced CT in solid tumor-bearing dogs treated with toceranib phosphate. Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association, 2020, Volume: 61, Issue:4 Topics: Animals; Antineoplastic Agents; Contrast Media; Cross-Sectional Studies; Dog Diseases; Dogs; Female; Humans; Indoles; Male; Neoplasms; Pyrroles; Retrospective Studies; Tomography, X-Ray Computed	2020
Assessment of postoperative adjuvant treatment using toceranib phosphate against adenocarcinoma in dogs. Journal of veterinary internal medicine, 2020, Volume: 34, Issue:3 Topics: Adenocarcinoma; Animals; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Dog Diseases; Dogs; Female; Indoles; Male; Neoplasm Recurrence, Local; Neoplasms; Pyrroles; Retrospective Studies; Treatment Outcome; Tumor Microenvironment; Vascular Endothelial Growth Factor Receptor-2	2020
Antimicrobial activity of harzianic acid against Natural product research, 2021, Volume: 35, Issue:23 Topics: Animals; Anti-Bacterial Agents; Cat Diseases; Cats; Dog Diseases; Dogs; Hydroxybutyrates; Microbial Sensitivity Tests; Pyrroles; Staphylococcal Infections; Staphylococcus	2021
A canine case of malignant melanoma carrying a KIT c.1725_1733del mutation treated with toceranib: a case report and in vitro analysis. BMC veterinary research, 2021, Apr-07, Volume: 17, Issue:1 Topics: Animals; Antineoplastic Agents; Base Sequence; Dog Diseases; Dogs; Gene Deletion; Genetic Predisposition to Disease; Gingival Neoplasms; Indoles; Lymphatic Metastasis; Male; Melanoma; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-kit; Pyrroles	2021
Toceranib phosphate-associated nephrotic syndrome in a dog: a case report. BMC veterinary research, 2021, Apr-07, Volume: 17, Issue:1 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Humans; Indoles; Nephrotic Syndrome; Pyrroles	2021
Evaluation of palliative therapy, alone or in combination with toceranib phosphate, in dogs diagnosed with metastatic or recurrent beta-cell neoplasia. New Zealand veterinary journal, 2021, Volume: 69, Issue:4 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Hospitals, Animal; Hospitals, Teaching; Indoles; Insulinoma; Palliative Care; Pancreatic Neoplasms; Pyrroles; Retrospective Studies	2021
Treatment of advanced-stage canine nasal carcinomas with toceranib phosphate: 23 cases (2015-2020). The Journal of small animal practice, 2021, Volume: 62, Issue:10 Topics: Animals; Antineoplastic Agents; Carcinoma; Dog Diseases; Dogs; Indoles; Nose Neoplasms; Pyrroles; Retrospective Studies	2021
Increased incidence of gastrointestinal toxicity in canine cancer patients treated with concurrent abdominal radiation therapy and toceranib phosphate. Veterinary and comparative oncology, 2022, Volume: 20, Issue:1 Topics: Abdomen; Animals; Dog Diseases; Dogs; Humans; Incidence; Indoles; Neoplasms; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies	2022
Toceranib phosphate (Palladia) for the treatment of canine exocrine pancreatic adenocarcinoma. BMC veterinary research, 2021, Aug-11, Volume: 17, Issue:1 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Indoles; Male; Pancreatic Neoplasms; Pyrroles; Retrospective Studies	2021
Clinical outcome of dogs diagnosed with canine inflammatory mammary cancer treated with metronomic cyclophosphamide, a cyclooxygenase-2 inhibitor and toceranib phosphate. Veterinary and comparative oncology, 2022, Volume: 20, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Breast Neoplasms; Cyclooxygenase 2 Inhibitors; Cyclophosphamide; Dog Diseases; Dogs; Female; Indoles; Pyrroles; Retrospective Studies	2022
Long-term survival in a dog with primary hepatic neuroendocrine tumor treated with toceranib phosphate. The Journal of veterinary medical science, 2021, Oct-05, Volume: 83, Issue:10 Topics: Animals; Autopsy; Dog Diseases; Dogs; Indoles; Male; Neuroendocrine Tumors; Pyrroles	2021
Effects of toceranib phosphate (Palladia) monotherapy on multidrug resistant lymphoma in dogs. The Journal of veterinary medical science, 2017, Jul-19, Volume: 79, Issue:7 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Dog Diseases; Dogs; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Indoles; Lymphoma; Male; Pyrroles	2017
Prospective evaluation of toceranib phosphate in metastatic canine osteosarcoma. Veterinary and comparative oncology, 2018, Volume: 16, Issue:1 Topics: Animals; Antineoplastic Agents; Biomarkers; Bone Neoplasms; Dog Diseases; Dogs; Enzyme-Linked Immunosorbent Assay; Female; Indoles; Male; Osteosarcoma; Prospective Studies; Pyrroles; Survival Analysis; T-Lymphocytes, Regulatory; Vascular Endothelial Growth Factor A	2018
Combination toceranib and lomustine shows frequent high grade toxicities when used for treatment of non-resectable or recurrent mast cell tumours in dogs: A European multicentre study. Veterinary journal (London, England : 1997), 2017, Volume: 224 Topics: Animals; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Dog Diseases; Dogs; Europe; Indoles; Lomustine; Mast Cells; Neoplasm Recurrence, Local; Prednisolone; Prospective Studies; Pyrroles; Receptor Protein-Tyrosine Kinases; Skin Neoplasms	2017
Retrospective evaluation of toceranib (Palladia) treatment for canine metastatic appendicular osteosarcoma. The Canadian veterinary journal = La revue veterinaire canadienne, 2017, Volume: 58, Issue:10 Topics: Animals; Bone Neoplasms; Dog Diseases; Dogs; Female; Indoles; Lung Neoplasms; Male; Osteosarcoma; Pyrroles; Retrospective Studies; Treatment Outcome	2017
Effects of Toceranib Phosphate on the Hypothalamic-Pituitary-Thyroid Axis in Tumor-Bearing Dogs. Journal of veterinary internal medicine, 2018, Volume: 32, Issue:1 Topics: Animals; Autoantibodies; Dog Diseases; Dogs; Female; Hypothalamus; Hypothyroidism; Indoles; Male; Neoplasms; Pituitary Gland; Prospective Studies; Pyrroles; Thyroglobulin; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine	2018
PDGFR-α, PDGFR-β, VEGFR-2 and CD117 expression in canine mammary tumours and evaluation of the in vitro effects of toceranib phosphate in neoplastic mammary cell lines. The Veterinary record, 2018, 08-18, Volume: 183, Issue:7 Topics: Animals; Cell Line, Tumor; Dog Diseases; Dogs; Female; Indoles; Mammary Neoplasms, Animal; Proto-Oncogene Proteins c-kit; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Vascular Endothelial Growth Factor Receptor-2	2018
The anti-inflammatory effect of topical tofacitinib on immediate and late-phase cutaneous allergic reactions in dogs: a placebo-controlled pilot study. Veterinary dermatology, 2018, Volume: 29, Issue:3 Topics: Animals; Anti-Inflammatory Agents; Dermatitis, Atopic; Dog Diseases; Dogs; Hypersensitivity, Delayed; Hypersensitivity, Immediate; Inflammation; Pilot Projects; Piperidines; Pyrimidines; Pyrroles	2018
Successful management of lymphangiosarcoma in a puppy using a tyrosine kinase inhibitor. The Canadian veterinary journal = La revue veterinaire canadienne, 2018, Volume: 59, Issue:4 Topics: Animals; Dog Diseases; Dogs; Indoles; Lymphangiosarcoma; Lymphedema; Lymphography; Male; Protein Kinase Inhibitors; Pyrroles; Tomography, X-Ray Computed; Treatment Outcome	2018
The impact of toceranib, piroxicam and thalidomide with or without hypofractionated radiation therapy on clinical outcome in dogs with inflammatory mammary carcinoma. Veterinary and comparative oncology, 2018, Volume: 16, Issue:4 Topics: Animals; Antineoplastic Agents; Combined Modality Therapy; Dog Diseases; Dogs; Drug Therapy, Combination; Female; Indoles; Mammary Neoplasms, Animal; Neoplasm Staging; Piroxicam; Pyrroles; Radiation Dose Hypofractionation; Thalidomide; Treatment Outcome	2018
A retrospective study of proteinuria in dogs receiving toceranib phosphate. The Canadian veterinary journal = La revue veterinaire canadienne, 2018, Volume: 59, Issue:6 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Dog Diseases; Dogs; Female; Glucocorticoids; Incidence; Indoles; Male; Neoplasms; Proteinuria; Pyrroles; Retrospective Studies	2018
Retrospective evaluation of toceranib phosphate (Palladia®) use in the treatment of inoperable, metastatic, or recurrent canine pheochromocytomas: 5 dogs (2014-2017). BMC veterinary research, 2018, Sep-03, Volume: 14, Issue:1 Topics: Adrenal Gland Neoplasms; Animals; Dog Diseases; Dogs; Female; Indoles; Male; Pheochromocytoma; Pyrroles; Retrospective Studies; Treatment Outcome	2018
Retrospective evaluation of toceranib phosphate (Palladia®) use in the treatment of gastrointestinal stromal tumors of dogs. Journal of veterinary internal medicine, 2018, Volume: 32, Issue:6 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Gastrointestinal Neoplasms; Gastrointestinal Stromal Tumors; Indoles; Male; Mitotic Index; Prognosis; Progression-Free Survival; Pyrroles; Retrospective Studies	2018
Plasma cytokeratin-18 concentrations as noninvasive biomarker of early gastrointestinal toxicosis in dogs receiving toceranib. Journal of veterinary internal medicine, 2018, Volume: 32, Issue:6 Topics: Animals; Antineoplastic Agents; Biomarkers; Case-Control Studies; Dog Diseases; Dogs; Female; Gastrointestinal Diseases; Indoles; Keratin-18; Male; Mastocytosis; Prospective Studies; Pyrroles; Vascular Endothelial Growth Factor A	2018
Response and outcome following toceranib phosphate treatment for stage four anal sac apocrine gland adenocarcinoma in dogs: 15 cases (2013-2017). Journal of the American Veterinary Medical Association, 2019, Apr-15, Volume: 254, Issue:8 Topics: Adenocarcinoma; Anal Sacs; Animals; Apocrine Glands; Dog Diseases; Dogs; Indoles; Pyrroles; Quality of Life; Retrospective Studies; Treatment Outcome	2019
Suspected eccrine adenocarcinoma on footpad of the right hindlimb in a dog. The Journal of veterinary medical science, 2019, Jun-06, Volume: 81, Issue:6 Topics: Adenocarcinoma; Angiogenesis Inhibitors; Animals; Biopsy; Dog Diseases; Dogs; Hindlimb; Immunohistochemistry; Indoles; Keratins; Male; Pyrroles; Sweat Gland Neoplasms; Vimentin	2019
In this issue - May 2019: West Nile virus in horses · Treating horses with dexamethasone via nebulisation · Animal hoarding in NSW · Dangers of powdered washing soda for emesis in dogs · Pneumocystis in a dog following toceranib phosphate · Oxalate nephro Australian veterinary journal, 2019, Volume: 97, Issue:5 Topics: Animals; Anti-Inflammatory Agents; Asthma; Dexamethasone; Dog Diseases; Dogs; Emetics; Hoarding; Horse Diseases; Horses; Indoles; Nebulizers and Vaporizers; Nephrosis; New South Wales; Oxalates; Phascolarctidae; Pneumocystis; Pneumocystis Infections; Powders; Pyrroles; Vomiting; West Nile Fever; West Nile virus	2019
Confirmed case of Pneumocystis pneumonia in a Maltese Terrier × Papillon dog being treated with toceranib phosphate. Australian veterinary journal, 2019, Volume: 97, Issue:5 Topics: Animals; Dog Diseases; Dogs; Drug Combinations; Female; Indoles; Mast-Cell Sarcoma; Pneumonia, Pneumocystis; Pyrroles; Sulfadoxine; Treatment Outcome; Trimethoprim	2019
Retrospective evaluation of canine heart base tumours treated with toceranib phosphate (Palladia): 2011-2018. Veterinary and comparative oncology, 2019, Volume: 17, Issue:4 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Heart Neoplasms; Indoles; Male; Pyrroles; Retrospective Studies	2019
Presumptive primary intrathoracic mast cell tumours in two dogs. BMC veterinary research, 2019, Jun-17, Volume: 15, Issue:1 Topics: Animals; Antineoplastic Agents; Carcinoma; Dog Diseases; Dogs; Female; Indoles; Lung Neoplasms; Mast Cells; Pyrroles; Thoracic Neoplasms; Thoracic Wall	2019
A novel approach to treatment of lymphangiosarcoma in a boxer dog. The Journal of small animal practice, 2013, Volume: 54, Issue:6 Topics: Animals; Antibiotics, Antineoplastic; Dog Diseases; Dogs; Doxorubicin; Female; Indoles; Lymphangiosarcoma; Mammary Glands, Animal; Mammary Neoplasms, Animal; Neoplasm Recurrence, Local; Pyrroles; Survival Rate; Treatment Outcome	2013
Partial cytogenetic response with toceranib and prednisone treatment in a young dog with chronic monocytic leukemia. Anti-cancer drugs, 2013, Volume: 24, Issue:10 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Dog Diseases; Dogs; Female; Fusion Proteins, bcr-abl; In Situ Hybridization, Fluorescence; Indoles; Leukemia, Myeloid; Prednisone; Pyrroles; Translocation, Genetic; Treatment Outcome	2013
Evaluation of the adverse event profile and pharmacodynamics of toceranib phosphate administered to dogs with solid tumors at doses below the maximum tolerated dose. BMC veterinary research, 2013, Sep-30, Volume: 9 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Female; Indoles; Male; Neoplasms; Pyrroles; Vascular Endothelial Growth Factor A	2013
Maintenance therapy with toceranib following doxorubicin-based chemotherapy for canine splenic hemangiosarcoma. BMC veterinary research, 2015, Jun-11, Volume: 11 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Doxorubicin; Female; Hemangiosarcoma; Indoles; Male; Pyrroles; Splenic Neoplasms	2015
Activity of the DNA minor groove cross-linking agent SG2000 (SJG-136) against canine tumours. BMC veterinary research, 2015, Aug-19, Volume: 11 Topics: Animals; Antineoplastic Agents; Benzodiazepinones; Cell Line, Tumor; Cross-Linking Reagents; DNA; Dog Diseases; Dogs; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Screening Assays, Antitumor; Female; Flow Cytometry; Mice; Mice, Nude; Pyrroles; Xenograft Model Antitumor Assays	2015
Effects of Toceranib Phosphate on Systolic Blood Pressure and Proteinuria in Dogs. Journal of veterinary internal medicine, 2016, Volume: 30, Issue:4 Topics: Animals; Antineoplastic Agents; Blood Pressure; Case-Control Studies; Cohort Studies; Dog Diseases; Dogs; Hypertension; Indoles; Neoplasms; Prospective Studies; Protein-Tyrosine Kinases; Proteinuria; Pyrroles	2016
A pilot study of toceranib/vinblastine therapy for canine transitional cell carcinoma. BMC veterinary research, 2016, Nov-17, Volume: 12, Issue:1 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Transitional Cell; Dog Diseases; Dogs; Female; Indoles; Male; Pilot Projects; Pyrroles; Reproducibility of Results; Tomography, X-Ray Computed; Treatment Outcome; Ultrasonography; Urinary Bladder Neoplasms; Vinblastine	2016
Skin depigmentation associated with toceranib phosphate in a dog. Veterinary dermatology, 2017, Volume: 28, Issue:4 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Indoles; Male; Mastocytosis; Pyrroles; Skin; Skin Diseases; Skin Pigmentation	2017
Successful treatment of a metastatic, gastrointestinal stromal tumour in a dog with toceranib phosphate (Palladia). The Journal of small animal practice, 2017, Volume: 58, Issue:7 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Female; Gastrointestinal Stromal Tumors; Indoles; Mutation; Neoplasm Recurrence, Local; Proto-Oncogene Proteins c-kit; Pyrroles	2017
Catching cancer by the tail: new perspectives on the use of kinase inhibitors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-01, Volume: 15, Issue:11 Topics: Animals; Dog Diseases; Dogs; Indoles; Mast-Cell Sarcoma; Neoplasm Recurrence, Local; Pyrroles; Random Allocation; Receptor Protein-Tyrosine Kinases; Treatment Outcome	2009
Multi-center, placebo-controlled, double-blind, randomized study of oral toceranib phosphate (SU11654), a receptor tyrosine kinase inhibitor, for the treatment of dogs with recurrent (either local or distant) mast cell tumor following surgical excision. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jun-01, Volume: 15, Issue:11 Topics: Animals; Anorexia; Diarrhea; Disease Progression; Dog Diseases; Dogs; Female; Indoles; Male; Mast-Cell Sarcoma; Neoplasm Recurrence, Local; Pyrroles; Random Allocation; Receptor Protein-Tyrosine Kinases; Treatment Outcome; Vomiting	2009
Cancer drug approved for dogs. Journal of the American Veterinary Medical Association, 2009, Jul-15, Volume: 235, Issue:2 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Drug Approval; Indoles; Mastocytosis, Cutaneous; Protein-Tyrosine Kinases; Pyrroles	2009
RT-PCR-based tyrosine kinase display profiling of canine melanoma: IGF-1 receptor as a potential therapeutic target. Melanoma research, 2010, Volume: 20, Issue:1 Topics: Animals; Cell Line, Tumor; Dog Diseases; Dogs; Humans; Melanoma; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Reverse Transcriptase Polymerase Chain Reaction; Signal Transduction; Skin Neoplasms	2010
Cutaneous mast cell tumours in dogs. The Veterinary record, 2010, Mar-27, Volume: 166, Issue:13 Topics: Animals; Antineoplastic Agents; Dog Diseases; Dogs; Indoles; Mast-Cell Sarcoma; Pyrroles; Research; Skin Neoplasms	2010
Primary frontal sinus squamous cell carcinoma in three dogs treated with piroxicam combined with carboplatin or toceranib. Veterinary and comparative oncology, 2012, Volume: 10, Issue:3 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Carboplatin; Carcinoma, Squamous Cell; Dog Diseases; Dogs; Drug Therapy, Combination; Frontal Sinus; Indoles; Male; Paranasal Sinus Neoplasms; Piroxicam; Pyrroles; Receptor Protein-Tyrosine Kinases	2012
Preliminary evidence for biologic activity of toceranib phosphate (Palladia(®)) in solid tumours. Veterinary and comparative oncology, 2012, Volume: 10, Issue:3 Topics: Adenocarcinoma; Anal Gland Neoplasms; Anal Sacs; Animals; Antineoplastic Agents; Apocrine Glands; Bone Neoplasms; Carcinoma; Dog Diseases; Dogs; Female; Head and Neck Neoplasms; Indoles; Male; Neoplasms; Nose Neoplasms; Osteosarcoma; Pyrroles; Receptor Protein-Tyrosine Kinases; Skin Neoplasms; Thyroid Neoplasms	2012
Evaluation of expression and function of vascular endothelial growth factor receptor 2, platelet derived growth factor receptors-alpha and -beta, KIT, and RET in canine apocrine gland anal sac adenocarcinoma and thyroid carcinoma. BMC veterinary research, 2012, May-25, Volume: 8 Topics: Anal Gland Neoplasms; Anal Sacs; Animals; Carcinoma; Dog Diseases; Dogs; Female; Gene Expression Regulation, Neoplastic; Indoles; Male; Proto-Oncogene Proteins c-kit; Proto-Oncogene Proteins c-ret; Pyrroles; Receptors, Platelet-Derived Growth Factor; RNA, Messenger; Thyroid Neoplasms; Vascular Endothelial Growth Factor Receptor-2	2012
Proof of target for SU11654: inhibition of KIT phosphorylation in canine mast cell tumors. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-15, Volume: 9, Issue:15 Topics: Animals; Dog Diseases; Dogs; Enzyme Inhibitors; Indoles; Mast Cells; Mast-Cell Sarcoma; Mitogen-Activated Protein Kinases; Neoplasm Metastasis; Phosphorylation; Proto-Oncogene Proteins c-kit; Pyrroles; Recurrence	2003