Page last updated: 2024-08-18

pyrroles and Cancer of Head

pyrroles has been researched along with Cancer of Head in 25 studies

Research

Studies (25)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's8 (32.00)29.6817
2010's14 (56.00)24.3611
2020's3 (12.00)2.80

Authors

AuthorsStudies
Cooper, PA; Khurram, SA; Loadman, PM; McCaul, J; Morais, GR; Patterson, LH; Pors, K; Presa, D; Sadiq, M; Shnyder, SD; Smarakan, S; Sutherland, M; Zubir, AZA1
Barry, C; Betancourt, O; Blot, V; Coronella, J; D'Hooge, F; Fujita, R; Galvan, D; Gymnopoulos, M; Hartley, JA; Howard, PW; Lieuw, V; Newman, R; Nguyen, S; Pardo, R; Patel, N; Snedden, J; Stewart, C; Vijayakrishnan, B; Villicana, J; Wojciak, J; Wong, E1
Lang, L; Shay, C; Teng, Y; Wang, X; Xiong, Y; Zhao, X1
Allen, CT; Clavijo, PE; Gunti, S; Hong, Y; Schmitt, NC; Van Waes, C; Ye, W1
Davies, BR; Forster, DM; Illidge, TM; Mukherjee, D; Searle, EJ; Stratford, IJ; Telfer, BA; Williams, KJ1
Ji, T; Ong, HS; Wang, LZ; Yu, ZW; Zhang, CP1
Islam, M; Kumar, B; Sharma, S; Teknos, TN1
Grandis, JR; Johnson, DE; Li, C; Yazbeck, VY; Zang, Y1
Aderhold, C; Birk, R; Faber, A; Hörmann, K; Schultz, JD; Sommer, JU; Umbreit, C; Weiss, C1
Cui, CH; Duda, DG; Jain, RK; Jeong, HS; Jones, D; Liao, S; Padera, TP; Wattson, DA; Willett, CG1
Affolter, A; Brenner, W; Brieger, J; Heimes, AS; Jensen, A; Mann, WJ; Mayer, A; Samosny, G; Schneider, J; Sommer, K; Stenzinger, A; Weichert, W1
Bozec, A; Etienne-Grimaldi, MC; Fischel, JL; Milano, G; Sudaka, A; Toussan, N1
Choong, NW; Cohen, EE; Dekker, A; Hu, HS; Ivy, P; Karrison, TG; Kozloff, M; Taber, D; Vokes, EE; Wade, J1
Andreiuolo, F; Bobos, M; Calderaro, J; Fountzilas, G; Fragkoulidi, A; Kalogera-Fountzila, A; Marselos, M; Nikolaidou, M1
Bompas, E; Dillies, AF; Duprez, T; Faivre, S; Guigay, J; Henry, S; Kaminsky, MC; Machiels, JP; Michoux, N; Moxhon, A; Rommel, D; Schmitz, S; Zanetta, S1
Alvarez, F; Beaver, L; Bryan, J; Carreras, J; Clifford, C; Ettinger, S; Fulton, L; Gauthier, M; Gill, V; Gillings, S; Haney, S; Henry, C; Hershey, B; Higginbotham, ML; Hillman, L; Jones, P; Kiselow, M; Klein, MK; Krick, E; Ladue, T; London, C; Mathie, T; McNeill, C; Novasad, A; Phillips, B; Stingle, N; Thamm, D; Vail, DM; Vaughan, A; Vickery, K1
Knecht, R; Kurzweg, T; Laban, S; Möckelmann, N1
Burrows, FJ; Dennis, M; Dohadwala, M; Dubinett, SM; Elashoff, D; Hu, D; Lawhon, T; Lee, JM; Lin, Y; Luo, J; St John, MA; Wang, G; Zaknoen, SL1
Baselga, J; Hammond, LA1
Curran, WJ1
Bekele, BN; Bucana, CD; Doan, DD; Fidler, IJ; Greenberg, JS; Holsinger, FC; Jasser, SA; Myers, JN; Schiff, BA; Swan, EA; Younes, MN1
Cooney, MM; Dowlati, A; Hoppel, CL; Ingalls, ST; Ivy, P; Ksenich, P; Lavertu, P; Makar, V; McCrae, K; McPeak, RJ; Overmoyer, B; Remick, S; Tserng, KY1
Aliff, T; Fleisher, M; Fury, MG; Gerald, W; Hann, L; Lis, E; Pfister, DG; Venkatraman, E; Wong, R; Zahalsky, A1
Cheson, BD; Conley, BA; Gore-Langton, RE1

Reviews

4 review(s) available for pyrroles and Cancer of Head

ArticleYear
Dermatofibrosarcoma protuberans on the right neck with superior vena cava syndrome: case report and literature review.
    International journal of oral and maxillofacial surgery, 2013, Volume: 42, Issue:6

    Topics: Adult; Antineoplastic Agents; Dermatofibrosarcoma; Head and Neck Neoplasms; Humans; Indoles; Male; Neck; Neoplasm Recurrence, Local; Pyrroles; Sunitinib; Superior Vena Cava Syndrome; Thorax; Vena Cava, Superior

2013
Current treatment options for recurrent/metastatic head and neck cancer: a post-ASCO 2011 update and review of last year's literature.
    European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2012, Volume: 269, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Benzodioxoles; Carcinoma, Squamous Cell; Cetuximab; Combined Modality Therapy; Dasatinib; ErbB Receptors; Fluorouracil; Gefitinib; Head and Neck Neoplasms; Humans; Indoles; Neoplasm Recurrence, Local; Palliative Care; Pyrimidines; Pyrroles; Quinazolines; Quinazolinones; Salvage Therapy; Squamous Cell Carcinoma of Head and Neck; Sunitinib; Thiazoles

2012
HER-targeted tyrosine-kinase inhibitors.
    Oncology, 2002, Volume: 63 Suppl 1

    Topics: Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Enzyme Inhibitors; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Head and Neck Neoplasms; Humans; Lung Neoplasms; Morpholines; Ovarian Neoplasms; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles; Quinazolines; Receptor, ErbB-2

2002
New chemotherapeutic agents: update of major chemoradiation trials in solid tumors.
    Oncology, 2002, Volume: 63 Suppl 2

    Topics: Alkyl and Aryl Transferases; Angiogenesis Inhibitors; Angiostatins; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Dose Fractionation, Radiation; Drugs, Investigational; Endothelial Growth Factors; Enzyme Inhibitors; Esophageal Neoplasms; Farnesyltranstransferase; Female; Head and Neck Neoplasms; Humans; Indoles; Intercellular Signaling Peptides and Proteins; Isoenzymes; Laryngeal Neoplasms; Lung Neoplasms; Lymphokines; Male; Membrane Proteins; Neoplasms; Peptide Fragments; Plasminogen; Prostaglandin-Endoperoxide Synthases; Prostatic Neoplasms; Pyrroles; Radiotherapy, Adjuvant; Randomized Controlled Trials as Topic; Treatment Outcome; Uterine Cervical Neoplasms; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors

2002

Trials

5 trial(s) available for pyrroles and Cancer of Head

ArticleYear
Phase II study of sunitinib malate in head and neck squamous cell carcinoma.
    Investigational new drugs, 2010, Volume: 28, Issue:5

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Demography; Disease Progression; Female; Head and Neck Neoplasms; Humans; Indoles; Male; Middle Aged; Pyrroles; Sunitinib; Survival Analysis; Tomography, X-Ray Computed

2010
A phase II study of sunitinib in patients with recurrent and/or metastatic non-nasopharyngeal head and neck cancer.
    Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:4

    Topics: Aged; Angiogenesis Inhibitors; Anorexia; Area Under Curve; Carcinoma, Squamous Cell; Drug Administration Schedule; Fatigue; Female; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Immunohistochemistry; Indoles; Male; Metabolic Clearance Rate; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrroles; Sunitinib; Survival Analysis; Thrombocytopenia; Treatment Outcome; Vascular Endothelial Growth Factor A

2010
Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck: GORTEC 2006-01.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Jan-01, Volume: 28, Issue:1

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Female; Head and Neck Neoplasms; Humans; Indoles; Magnetic Resonance Angiography; Male; Middle Aged; Neoplasm Metastasis; Neoplasm Recurrence, Local; Pyrroles; Sunitinib

2010
A phase IB clinical and pharmacokinetic study of the angiogenesis inhibitor SU5416 and paclitaxel in recurrent or metastatic carcinoma of the head and neck.
    Cancer chemotherapy and pharmacology, 2005, Volume: 55, Issue:3

    Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Combined Chemotherapy Protocols; Female; Head and Neck Neoplasms; Humans; Indoles; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Paclitaxel; Pyrroles

2005
A Phase II study of SU5416 in patients with advanced or recurrent head and neck cancers.
    Investigational new drugs, 2007, Volume: 25, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Blood Pressure; Female; Head and Neck Neoplasms; Heart Rate; Humans; Indoles; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasms, Squamous Cell; Pyrroles; Regional Blood Flow; Ultrasonography; Vascular Endothelial Growth Factor A

2007

Other Studies

16 other study(ies) available for pyrroles and Cancer of Head

ArticleYear
Cytochrome P450 isoforms 1A1, 1B1 AND 2W1 as targets for therapeutic intervention in head and neck cancer.
    Scientific reports, 2021, 09-23, Volume: 11, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cohort Studies; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Cytochrome P450 Family 2; Female; Head and Neck Neoplasms; Heterocyclic Compounds, 3-Ring; Humans; Indoles; Mice; Prodrugs; Pyrroles; Xenograft Model Antitumor Assays

2021
TR1801-ADC: a highly potent cMet antibody-drug conjugate with high activity in patient-derived xenograft models of solid tumors.
    Molecular oncology, 2020, Volume: 14, Issue:1

    Topics: Animals; Antineoplastic Agents; Benzodiazepines; Biliary Tract Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Immunoconjugates; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oncogenes; Proto-Oncogene Proteins c-met; Pyrroles; Rats; Rats, Sprague-Dawley; Stomach Neoplasms; Tissue Array Analysis; Xenograft Model Antitumor Assays

2020
Simultaneously inactivating Src and AKT by saracatinib/capivasertib co-delivery nanoparticles to improve the efficacy of anti-Src therapy in head and neck squamous cell carcinoma.
    Journal of hematology & oncology, 2019, 12-05, Volume: 12, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzodioxoles; Biomarkers, Tumor; Cell Movement; Cell Proliferation; Drug Delivery Systems; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Nanoparticles; Neoplasm Invasiveness; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Quinazolines; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; src-Family Kinases; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2019
ASTX660, an antagonist of cIAP1/2 and XIAP, increases antigen processing machinery and can enhance radiation-induced immunogenic cell death in preclinical models of head and neck cancer.
    Oncoimmunology, 2020, Volume: 9, Issue:1

    Topics: Animals; Antigen Presentation; Apoptosis; Cell Line, Tumor; Head and Neck Neoplasms; Immunogenic Cell Death; Inhibitor of Apoptosis Proteins; Mice; Morpholines; Piperazines; Pyrroles

2020
Akt inhibition improves long-term tumour control following radiotherapy by altering the microenvironment.
    EMBO molecular medicine, 2017, Volume: 9, Issue:12

    Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Combined Modality Therapy; Endothelial Cells; Female; Gamma Rays; Head and Neck Neoplasms; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Positron Emission Tomography Computed Tomography; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Transplantation, Heterologous; Tumor Microenvironment; Vascular Endothelial Growth Factor A

2017
Atorvastatin inhibits RhoC function and limits head and neck cancer metastasis.
    Oral oncology, 2013, Volume: 49, Issue:8

    Topics: Animals; Atorvastatin; Carcinoma, Squamous Cell; Head and Neck Neoplasms; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Signaling System; Mice; Neoplasm Metastasis; Phosphorylation; Pyrroles; rho GTP-Binding Proteins; rhoC GTP-Binding Protein; STAT3 Transcription Factor

2013
Single-agent obatoclax (GX15-070) potently induces apoptosis and pro-survival autophagy in head and neck squamous cell carcinoma cells.
    Oral oncology, 2014, Volume: 50, Issue:2

    Topics: Apoptosis; Autophagy; Carcinoma, Squamous Cell; Cell Survival; Head and Neck Neoplasms; Humans; Indoles; Inhibitory Concentration 50; Proto-Oncogene Proteins c-bcl-2; Pyrroles

2014
Targeting mTOR and AREG with everolimus, sunitinib and sorafenib in HPV-positive and -negative SCC.
    Anticancer research, 2015, Volume: 35, Issue:4

    Topics: Amphiregulin; Carcinoma, Squamous Cell; EGF Family of Proteins; Everolimus; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Human papillomavirus 16; Humans; Indoles; Molecular Targeted Therapy; Niacinamide; Papillomaviridae; Phenylurea Compounds; Pyrroles; Sirolimus; Sorafenib; Squamous Cell Carcinoma of Head and Neck; Sunitinib; TOR Serine-Threonine Kinases

2015
Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases.
    Journal of the National Cancer Institute, 2015, Volume: 107, Issue:9

    Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Colonic Neoplasms; Head and Neck Neoplasms; Humans; Indoles; Lymph Nodes; Lymphatic Metastasis; Mice; Neovascularization, Pathologic; Pyrroles; Sunitinib

2015
Multikinase inhibitors sorafenib and sunitinib as radiosensitizers in head and neck cancer cell lines.
    Head & neck, 2017, Volume: 39, Issue:4

    Topics: Antineoplastic Agents; Apoptosis; Biopsy, Needle; Carcinoma, Squamous Cell; Cell Line, Tumor; Combined Modality Therapy; Disease-Free Survival; Head and Neck Neoplasms; Humans; Immunohistochemistry; Indoles; Niacinamide; Phenylurea Compounds; Prognosis; Pyrroles; Radiation-Sensitizing Agents; Risk Assessment; Sorafenib; Squamous Cell Carcinoma of Head and Neck; Sunitinib

2017
Combination of sunitinib, cetuximab and irradiation in an orthotopic head and neck cancer model.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2009, Volume: 20, Issue:10

    Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cetuximab; Combined Modality Therapy; Disease Models, Animal; Drug Evaluation, Preclinical; Female; Head and Neck Neoplasms; Humans; Indoles; Mice; Mice, Nude; Neoplasm Transplantation; Pyrroles; Radiotherapy; Sunitinib; Transplantation, Heterologous; Xenograft Model Antitumor Assays

2009
Preliminary evidence for biologic activity of toceranib phosphate (Palladia(®)) in solid tumours.
    Veterinary and comparative oncology, 2012, Volume: 10, Issue:3

    Topics: Adenocarcinoma; Anal Gland Neoplasms; Anal Sacs; Animals; Antineoplastic Agents; Apocrine Glands; Bone Neoplasms; Carcinoma; Dog Diseases; Dogs; Female; Head and Neck Neoplasms; Indoles; Male; Neoplasms; Nose Neoplasms; Osteosarcoma; Pyrroles; Receptor Protein-Tyrosine Kinases; Skin Neoplasms; Thyroid Neoplasms

2012
Apricoxib upregulates 15-PGDH and PGT in tobacco-related epithelial malignancies.
    British journal of cancer, 2012, Aug-07, Volume: 107, Issue:4

    Topics: Cadherins; Carcinoma, Squamous Cell; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cyclooxygenase 2 Inhibitors; Head and Neck Neoplasms; Humans; Hydroxyprostaglandin Dehydrogenases; Organic Anion Transporters; Pyrroles; Smoking; Squamous Cell Carcinoma of Head and Neck; Sulfonamides; Up-Regulation; Vimentin

2012
Epidermal growth factor receptor blockade potentiates apoptosis mediated by Paclitaxel and leads to prolonged survival in a murine model of oral cancer.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Aug-01, Volume: 9, Issue:8

    Topics: Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Blotting, Western; Cell Death; Cell Line, Tumor; Dose-Response Relationship, Drug; ErbB Receptors; Head and Neck Neoplasms; Humans; In Situ Nick-End Labeling; Ligands; Male; Mice; Mice, Nude; Microscopy, Fluorescence; Mouth Neoplasms; Neoplasms; Paclitaxel; Phosphorylation; Propidium; Pyrimidines; Pyrroles; Tongue; Tongue Neoplasms; Tyrosine

2003
Off-label uses of sorafenib and sunitinib.
    Technology Evaluation Center Assessment Program. Executive summary, 2008, Volume: 22, Issue:11

    Topics: Adenocarcinoma; Angiogenesis Inhibitors; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; Digestive System Neoplasms; Drug Approval; Female; Gastrointestinal Stromal Tumors; Head and Neck Neoplasms; Humans; Indoles; Male; Melanoma; Neoplasms, Squamous Cell; Product Labeling; Pyridines; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome; United States; United States Food and Drug Administration

2008
Clinical trials, referral resource. Treatment of advanced or recurrent squamous cell carcinoma of the head and neck.
    Oncology (Williston Park, N.Y.), 2000, Volume: 14, Issue:4

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Carcinoma, Squamous Cell; Cetuximab; Clinical Trials as Topic; Combined Modality Therapy; Head and Neck Neoplasms; Humans; Indoles; Platinum Compounds; Pyrroles; Recurrence

2000