Page last updated: 2024-08-18

pyrroles and Cancer of Colon

pyrroles has been researched along with Cancer of Colon in 96 studies

Research

Studies (96)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (2.08)	18.7374
1990's	6 (6.25)	18.2507
2000's	39 (40.63)	29.6817
2010's	42 (43.75)	24.3611
2020's	7 (7.29)	2.80

Authors

Authors	Studies
Liu, XY; Xu, J; Zhang, H; Zhang, P	1
Barry, C; Betancourt, O; Blot, V; Coronella, J; D'Hooge, F; Fujita, R; Galvan, D; Gymnopoulos, M; Hartley, JA; Howard, PW; Lieuw, V; Newman, R; Nguyen, S; Pardo, R; Patel, N; Snedden, J; Stewart, C; Vijayakrishnan, B; Villicana, J; Wojciak, J; Wong, E	1
Chen, L; Chen, S; Wang, Q; Yang, HS; Zhang, Y; Zheng, H; Zhu, J	1
Aka, Y; Kilic-Kurt, Z; Kutuk, O	1
Chen, X; Chen, XP; Datta, PK; Dong, SL; Dong, W; Leng, C; Luo, X; Wang, C; Yin, P; Zhang, BH; Zhang, BX	1
Li, G; Liang, W; Shen, Y; Tian, X; Zhang, C; Zhang, Y	1
Burstroem, L; Ernst, M; Khakham, Y; Lessene, G; Love, CG; Lowell, C; Masson, F; Monard, S; O'Donoghue, RJJ; Poh, AR; Preaudet, A; Putoczki, TL; Sieber, O; Tsui, C; Whitehead, L	1
Aldarouish, M; Chen, FX; Chen, YQ; Liu, JQ; Pan, N; Wang, LX; Zheng, L; Zhou, ZH	1
Hirasaka, K; Nagano, H; Nikawa, T; Ohno, A; Teshima-Kondo, S; Tomida, C; Uchida, T; Yamagishi, N	1
Cheng, L; Dai, L; Deng, H; Jiang, Q; Li, J; Li, Y; Li, Z; Lin, Y; Liu, L; Liu, Y; Shi, G; Su, X; Wang, H; Wang, Q; Wei, Y; Yang, Q; Yang, S; Yang, Y; Yu, D; Zhang, H; Zhang, S; Zhang, X; Zhang, Y	1
Jue, L; Li, X; Pang, X; Wang, S	1
Kuznietsova, HM; Ogloblya, OV; Rybalchenko, VK	1
Brewer, M; Janakiram, NB; Mohammed, A; Rao, CV; Steele, VE; Vedala, K	1
Campiani, G; Greene, LM; Nolan, DP; Regan-Komito, D; Williams, DC; Zisterer, DM	1
Gruidl, M; Timme, CR; Yeatman, TJ	1
Babuta, EN; Denis, EO; Dzhus, OI; Garmanchuk, LV; Khranovskaia, NN; Linchak, OV; Nikolaenko, TV; Nikulina, VV; Rybal'chenko, VK	1
Jia, B; Liu, H; Liu, Z; Ma, T; Shi, J; Sun, X; Wang, F; Wu, Y; Yu, X; Zhao, H	1
Chen, HY; Ding, KF; Hu, LF; Hu, YT; Li, Q; Liu, Y; Ruan, SQ; Wang, ZH; Xiao, Q; Zhang, SZ; Zheng, S	1
Connell, JJ; Döme, B; Fehniger, TE; Marko-Varga, G; Sugihara, Y; Török, S; Tóvári, J; Végvári, Á	1
Bonzi, MC; Craparotta, I; Gariboldi, MB; Giovannardi, S; Mancini, M; Monti, E; Taiana, E	1
Cui, CH; Duda, DG; Jain, RK; Jeong, HS; Jones, D; Liao, S; Padera, TP; Wattson, DA; Willett, CG	1
Jeong, YK; Jung, WG; Kim, EH; Lee, H	1
de Haas, RR; Griffioen, AW; Honeywell, RJ; Peters, GJ; Poel, D; Rovithi, M; Verheul, HM	1
Asai, T; Baba, K; Ida, T; Katanasaka, Y; Koizumi, F; Maeda, N; Oku, N; Shimizu, K	1
Chu, ZH; Luo, XJ; Zeng, QL; Zhou, K	1
Baba, M; Hiramatsu, Y; Kamiya, K; Kawabata, T; Kikuchi, H; Kitagawa, M; Kondo, K; Konno, H; Ohta, M; Tanaka, T; Yamamoto, M	1
Datta, PK; Halder, SK; Zhang, B; Zhang, S	1
Chen, SH; Divino, CM; Kao, J; Ma, G; Meseck, M; Ozao-Choy, J; Pan, PY; Schwartz, M; Sung, M; Wang, GX	1
Calderan, L; Daducci, A; Degrassi, A; Farace, P; Galiè, M; Marzola, P; Merigo, F; Nicolato, E; Pesenti, E; Sbarbati, A	1
Burkitt, K; Chun, SY; Dang, DT; Dang, LH	1
Aranganathan, S; Gopalan, R; Nalini, N; Selvam, JP	1
Jin, H; Koo, PT; Tsang, DJ; Xiao, H; Yang, CS; Yang, Z	1
Azzoli, CG; Calcutt, MW; Janjigian, YY; Kris, MG; Krug, LM; Lee, W; Miller, VA; Rizvi, NA; Senturk, E	1
Amaravadi, R	1
Baba, M; Hiramatsu, Y; Kamiya, K; Kawabata, T; Kikuchi, H; Konno, H; Ohta, M; Tanaka, T; Yamamoto, M	1
Guillén-Ponce, C; Mena, AC; Pulido, EG	1
Cai, T; Ding, W; He, Q; Lu, W; Tu, C; Wu, R; Yang, B; Yang, L; Zhu, H	1
Garlapati, A; Tangeda, SJ	1
Carpentino, JE; Eaton, K; Higgins, PD; Huang, EH; Hynes, MJ; Johnson, LA	1
Barkume, M; Chourasia, M; Juvekar, A; Kamal, A; Khan, MN; Pal-Bhadra, M; Pushpavalli, SN; Ramaiah, MJ; Reddy, KS; Sastry, GN; Shetti, RV; Srinivas, C; Zingde, S	1
Altman, J; Kuzel, T; Parajuli, R; Perdekamp, M; Tallman, M	1
de Jong, S; de Vries, EG; Kleibeuker, JH; Oenema, T; Pennarun, B; Stegehuis, JH	2
Chen, P; Fink, BE; Gavai, AV; Goyal, B; Kim, SH; Lee, FY; Mastalerz, H; Norris, D; Oppenheimer, S; Tokarski, JS; Vite, GD; Wong, TW; Zhang, H; Zhao, Y	1
Gong, P; Lv, Y; Wang, S; Zhang, G; Zhang, N; Zhao, Y	1
Farsaci, B; Higgins, JP; Hodge, JW	1
DeCastro, A; Janakiram, NB; Lee, HJ; Paul, S; Rao, CV; Reddy, BS; Simi, B; Smolarek, AK; So, JY; Steele, V; Suh, N; Wang, CX	1
Budak, K; Pestalozzi, B; Weisshaupt, Ch	1
Choi, CI; Janakiram, NB; Li, Q; Mohammed, A; Rao, CV; Steele, VE; Zhang, Y	1
Casto, BC; Knobloch, TJ; Lubet, RA; Pereira, MA; Steele, VE; Warner, BM; Weghorst, CM	1
Chieco, P; Guarnieri, T; Laufer, S; Munarini, A; Storci, G; Tavolari, S	1
Guan, F; Ju, J; Li, G; Liu, AB; Sun, Y; Yang, CS; Yang, Z	1
Ayuzawa, R; Doi, C; Kawabata, A; Matsuzuka, T; Nguyen, TA; Pickel, L; Reischman, J; Seiler, G; Tamura, M	1
Bai, W; He, AR; Hwang, J; Marshall, J; Mikhail, S; Navarro, R; Pishvaian, M; Shivapurkar, N; Wellstein, A	1
Brown, MF; Chandler, J; Dudgeon, C; Shu, Y; Sun, J; Sun, Q; Xu, X; Yu, J; Zhang, L	1
Benhamouda, N; Carpentier, AF; Colussi, O; Dubreuil, O; Marcheteau, E; Pernot, S; Sandoval, F; Taieb, J; Tartour, E; Terme, M	1
Abe, S; Araki, T; Fushimi, A; Higaki, K; Ishikawa, K; Kimura, T; Molema, G; Ogawara, K; Yoshizawa, Y	1
Almenara, J; Alotaibi, M; Biggers, JW; Brown, R; Di, X; Emery, SM; Gewirtz, DA; Gupton, JT; Henderson, SC; Nguyen, T; White, KL	1
Buchanan, GO; Feling, RH; Fenical, W; Jensen, PR; Kauffman, CA; Mincer, TJ	1
Ellis, LM	1
Fedier, A; Fink, D; Fowst, C; Geroni, C; Haller, U; Marchini, S; Tursi, J	1
Broggini, M; Colombo, T; Geroni, C; Marchini, S; Sabatino, MA	1
Abrams, T; Calderan, L; Crescimanno, C; Degrassi, A; Farace, P; Giusti, A; Marzola, P; Murray, L; Nicolato, E; Osculati, F; Pesenti, E; Sbarbati, A; Terron, A	1
Cherrington, JM; Manning, WC; McArthur, G; Morimoto, AM; Smolich, BD; Tan, N; Toner, GC; West, K	1
Anastasiadis, PZ; Fields, AP; Liu, Y; Thompson, EA; Zhang, J	1
Castedo, M; Feunteun, J; Horne, D; Kroemer, G; Lenoir, G; Medema, R; Perfettini, JL; Raslova, H; Roumier, T; Vainchenker, W; Valent, A; Yakushijin, K	1
Dignam, J; Gajewski, TF; Karczmar, G; Kindler, H; MacEneany, P; Medved, M; Mitchell, MT; Stadler, WM; Vokes, E; Yang, C	1
Hiramatsu, N; Mamo, JC; Pal, S; Takechi, R	1
Fu, M; Guo, S; Li, S; Liang, X; Lin, C; Lu, H; Wu, M; Zhang, X; Zheng, Z	1
Boger, DL; Hamasaki, A; Hwang, I; Zimpleman, JM	1
Guichard, SM; Jodrell, DI; Macpherson, JS; Thurston, DE	1
Chikahisa, LM; Hasegawa, H; Kitajima, M; Kubota, T; Ozawa, S; Watanabe, M; Yamada, Y; Yorozuya, K	1
Calderan, L; Crescimanno, C; Degrassi, A; Farace, P; Giusti, A; Marzola, P; Nicolato, E; Osculati, F; Pesenti, E; Sandri, M; Sbarbati, A; Terron, A	1
Marian, B; Nohl, H; Rohr-Udilova, N; Stolze, K	1
Begent, RH; Hartley, JA; Howard, PW; Masterson, LA; Spanswick, VJ; Thurston, DE	1
Khor, TO; Kong, AN; Kopelovich, L; Rao, CV; Reddy, BS; Steele, VE; Wang, CX; Zheng, X	1
Borner, MM	1
Chao, TH; Cusack, JC; Liu, R; Neuteboom, ST; Niu, W; Palladino, MA; Palombella, VJ; Pien, C; Xia, L	1
Boschi, F; D'Onofrio, M; Faccioli, N; Marzola, P; Pozzi Mucelli, R; Sbarbati, A	1
Bartolini, G; Bonafè, M; Brighenti, E; Ferreri, C; Guarnieri, T; Laufer, S; Manara, S; Marini, M; Tavolari, S; Tomasi, V	1
Lin, Y; Reddy, BS; Xiao, H; Yang, CS; Zhang, Q	1
Aranganathan, S; Nalini, N; Panneer Selvam, J	1
Bar-Eli, M; Fan, D; Fidler, IJ; Kerbel, RS; Kim, SJ; Kuwai, T; Nakamura, T; Sasaki, T; Villares, GJ; Wang, H; Zigler, M	1
Anderson, WK	1
Barrows, LR; Copp, BR; Ireland, CM; Kramer, RA; Radisky, DC; Swaffar, DS; Warters, RL	1
Basson, MD; Hong, F	1
Hioki, K; Kameshita, I; Mohri, T; Suzuki, S; Takatani, S; Tokunaga, R	1
Ebisu, H; Fukuda, Y; Furuta, H; Oomori, Y; Seto, S; Terashima, S	1
Bucana, CD; Davis, DW; Ellis, LM; Liu, W; McConkey, DJ; McMahon, G; Shaheen, RM; Wilson, MR; Zebrowski, BK	1
Ellis, LM; Liu, W; Shaheen, RM; Takahashi, Y	1
Edatsugi, H; Matsuba, Y; Matsunaga, A; Mita, I; Nakanishi, O	1
Bucana, CD; Davis, DW; Drazan, KE; Ellis, LM; Liu, W; McConkey, DJ; McMahon, G; Ogura, Y; Reinmuth, N; Shaheen, RM; Tseng, WW; Vellagas, R; Wieczorek, AA	1
Armatis, P; Feil, A; Halmos, G; Hebert, F; Kiaris, H; Nagy, A; Schally, AV; Sun, B; Szepeshazi, K	1
Alberts, DS; Dorr, RT; Islam, I; Skibo, EB	1
Lalezari, I; Schwartz, EL	1

Reviews

4 review(s) available for pyrroles and Cancer of Colon

Article	Year
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. Science & sports, 2023, Apr-04 Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide	2023
Understanding the molecular-based mechanism of action of the tyrosine kinase inhibitor: sunitinib. Anti-cancer drugs, 2010, Volume: 21 Suppl 1 Topics: Angiogenesis Inhibitors; Breast Neoplasms; Carcinoma, Renal Cell; Colonic Neoplasms; Drug Resistance, Neoplasm; Female; Gastrointestinal Stromal Tumors; Humans; Indoles; Lung Neoplasms; Neovascularization, Pathologic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Sunitinib	2010
A targeted approach for antiangiogenic therapy of metastatic human colon cancer. The American surgeon, 2003, Volume: 69, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Colonic Neoplasms; Colorectal Neoplasms; Endothelial Growth Factors; Extracellular Matrix; Humans; Indoles; Integrins; Intercellular Signaling Peptides and Proteins; Lymphokines; Neovascularization, Pathologic; Oxindoles; Propionates; Pyrroles; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2003
[Molecular targets in colon cancer]. Therapeutische Umschau. Revue therapeutique, 2006, Volume: 63, Issue:4 Topics: Angiogenesis Inhibitors; Antibiotics, Antineoplastic; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzamides; Camptothecin; Cetuximab; Clinical Trials as Topic; Clinical Trials, Phase II as Topic; Colonic Neoplasms; Drug Delivery Systems; ErbB Receptors; Gefitinib; Humans; Imatinib Mesylate; Indoles; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Phthalazines; Piperazines; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Quinazolines; Quinolones; Receptors, Platelet-Derived Growth Factor; Receptors, Somatomedin; Signal Transduction; Sirolimus; Sunitinib	2006

Trials

3 trial(s) available for pyrroles and Cancer of Colon

Article	Year
Effect of 12-week of aerobic exercise on hormones and lipid profile status in adolescent girls with polycystic ovary syndrome: A study during COVID-19. Science & sports, 2023, Apr-04 Topics: Actin Cytoskeleton; Actins; Adaptor Proteins, Signal Transducing; Adenocarcinoma; Adenosine Triphosphate; Adsorption; Adult; Africa, Eastern; Aged; Air Pollutants; Air Pollution; Air Pollution, Indoor; Alcohol Drinking; Allergens; Alzheimer Disease; Amyotrophic Lateral Sclerosis; Animals; Anti-Bacterial Agents; Antibodies; Antibodies, Immobilized; Antigen Presentation; Antigens, CD; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Antioxidants; Apoptosis; Aptamers, Nucleotide; Asthma; Asthma, Exercise-Induced; Atrophy; Autophagy; Azoospermia; Bacillus cereus; Bacterial Infections; Beclin-1; Bile Duct Neoplasms; Bile Ducts, Intrahepatic; Biofouling; Biological Monitoring; Biomarkers; Biomarkers, Tumor; Biosensing Techniques; Blastocyst; Bone Neoplasms; Bone Regeneration; Bronchoconstriction; Burkitt Lymphoma; C9orf72 Protein; Campylobacter; Campylobacter Infections; Campylobacter jejuni; Carcinogenesis; Carcinoma, Hepatocellular; Carcinoma, Pancreatic Ductal; Carcinoma, Squamous Cell; Cardiomyopathies; Caregivers; Carmine; Case-Control Studies; Catalysis; Cattle; Cause of Death; CCAAT-Enhancer-Binding Protein-alpha; CD8-Positive T-Lymphocytes; Cefepime; Cell Differentiation; Cell Line, Tumor; Cell Nucleus; Cell Transdifferentiation; Chelating Agents; Chemical and Drug Induced Liver Injury, Chronic; Chemoradiotherapy, Adjuvant; Child; Child, Preschool; China; Chlorquinaldol; Cholangiocarcinoma; Cholera; Chromatin; Clinical Trials as Topic; Cognitive Dysfunction; Cohort Studies; Colonic Neoplasms; Colorectal Neoplasms; Colorimetry; Cooking; Coordination Complexes; COVID-19; Creatinine; CRISPR-Cas Systems; Critical Care; Critical Illness; Cross-Sectional Studies; Cryopreservation; Cryoprotective Agents; Cysteine; Cytokines; Device Removal; Diet; Diet, High-Fat; Diet, Mediterranean; Dietary Supplements; Dimethyl Sulfoxide; Dipeptides; Disease Models, Animal; Dithiothreitol; DNA; DNA Repeat Expansion; DNA, Bacterial; DNA, Complementary; Dopamine; Electrochemical Techniques; Electrodes; Endocannabinoids; Environmental Exposure; Environmental Monitoring; Environmental Pollutants; Enzyme-Linked Immunosorbent Assay; Erlotinib Hydrochloride; Escherichia coli; Escherichia coli O157; Esophageal Neoplasms; Esophagitis, Peptic; Ethylene Glycol; Europium; Exanthema; Fallopian Tubes; Feces; Female; Fertilization in Vitro; Fluoresceins; Fluorescent Dyes; Follicle Stimulating Hormone; Follow-Up Studies; Food Microbiology; Forced Expiratory Volume; Forkhead Transcription Factors; Frontotemporal Dementia; G-Quadruplexes; Galactose; Gastroenteritis; Gastrointestinal Diseases; Gastrointestinal Microbiome; Gastrointestinal Neoplasms; Gastrointestinal Tract; Gene Frequency; Genetic Association Studies; Genetic Predisposition to Disease; Genital Neoplasms, Female; Genome-Wide Association Study; Genome, Viral; Genomics; Genotype; Glucose; Glutathione; Glycerol; Gold; Graphite; GTPase-Activating Proteins; Heat-Shock Proteins; Heme Oxygenase-1; Hepacivirus; Hepatitis C; Hepatocytes; Histamine; Histocompatibility Antigens Class II; Hoarseness; Hospice and Palliative Care Nursing; Humans; Hydrogen; Hydrogen Peroxide; Hydrogen Sulfide; Hydroxybenzoates; Hydroxyl Radical; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperthermia, Induced; Hysteroscopy; Immunoassay; Indigo Carmine; Inflammation; Inflammatory Bowel Diseases; Insulin Resistance; Intensive Care Units; Interleukin-11; Interleukin-6; Interleukins; Iodine Radioisotopes; Iran; Iridium; Islets of Langerhans; Kinetics; Lactation; Lactobacillus; Lactobacillus plantarum; Lamins; Latin America; Lead; Lectins; Leukopenia; Ligands; Limit of Detection; Lipopolysaccharides; Lipoprotein Lipase; Liver; Liver Cirrhosis; Liver Neoplasms; Lolium; Luminescent Measurements; Luminol; Lung; Luteinizing Hormone; Macrophages; Magnetic Phenomena; Magnetic Resonance Imaging; Male; Malnutrition; Maltose; Manganese Compounds; Maternal Nutritional Physiological Phenomena; Melatonin; Metabolic Engineering; Metal Nanoparticles; Metallocenes; Metaplasia; Methicillin-Resistant Staphylococcus aureus; Methylation; Mevalonic Acid; Mexico; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microbial Sensitivity Tests; Microbiota; MicroRNAs; Milk; Mitomycin; Molecular Diagnostic Techniques; Molecular Docking Simulation; Monte Carlo Method; Moringa oleifera; Multiple Sclerosis; Muscle Strength; Muscle, Skeletal; Nanocomposites; Nanotubes, Carbon; Neoadjuvant Therapy; Neoplasms; Neurodegenerative Diseases; Neurotransmitter Agents; NF-E2-Related Factor 2; Nickel; Nitrogen Dioxide; Non-alcoholic Fatty Liver Disease; Nucleic Acid Amplification Techniques; Nucleic Acid Hybridization; Nucleocapsid Proteins; Nutritional Status; Obesity; Osteogenesis; Osteosarcoma; Oxidation-Reduction; Oxides; Oxygen; Oxyquinoline; Pain; Palliative Care; Pancreatic Neoplasms; Pandemics; Particulate Matter; Peroxidase; Peroxidases; Phagocytosis; Phaseolus; Photothermal Therapy; Point-of-Care Systems; Polyethyleneimine; Polymers; Polymorphism, Single Nucleotide; Polysomnography; Postoperative Complications; Pregnancy; Pregnant Women; Prenatal Exposure Delayed Effects; Prevalence; Printing, Three-Dimensional; Probability; Probiotics; Prognosis; Prophages; Prospective Studies; Proteomics; Proto-Oncogene Proteins; Pseudomonas aeruginosa; Pseudomonas putida; Pulmonary Disease, Chronic Obstructive; Pulmonary Embolism; Pyridines; Pyrroles; Quality of Life; Quinolones; Rabbits; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Real-Time Polymerase Chain Reaction; Receptors, Histamine; Receptors, Histamine H2; Recombinases; Rectal Neoplasms; Reperfusion Injury; Respiration; Respiratory Function Tests; Respiratory Rate; Respiratory Sounds; Retrospective Studies; rho GTP-Binding Proteins; Risk Assessment; Risk Factors; RNA; RNA, Messenger; RNA, Ribosomal, 16S; Robotic Surgical Procedures; Running; Rural Population; Saccharomyces cerevisiae; Salpingectomy; Sarcopenia; SARS-CoV-2; Seeds; Semen; Sensitivity and Specificity; Sepsis; Shock, Septic; Signal Transduction; Silicon Dioxide; Silver; Sirtuin 1; Skin Neoplasms; Sleep Apnea, Obstructive; Soil; Spain; Spectrum Analysis, Raman; Sperm Retrieval; Spermatozoa; Spirometry; Staphylococcus aureus; STAT3 Transcription Factor; Stereoisomerism; Sterilization, Tubal; Stroke Volume; Sulfadiazine; Sulfites; Superoxide Dismutase; Surface Plasmon Resonance; tau Proteins; Testis; Testosterone; Thioredoxin-Disulfide Reductase; Thyroid Neoplasms; Thyroidectomy; Trans-Activators; Transcription Factor AP-1; Treatment Outcome; Triazoles; Triclosan; Trifluridine; Tumor Microenvironment; Tumor Necrosis Factor-alpha; United States; Uracil; Vagina; Vegetables; Ventricular Function, Left; Ventricular Pressure; Vibrio cholerae; Vietnam; Virulence; Vital Capacity; Vitrification; Walking; Water; Water Pollutants, Radioactive; Whole Genome Sequencing; Wind; YAP-Signaling Proteins; Zeolites; Zinc Oxide	2023
A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors. Cancer chemotherapy and pharmacology, 2010, Volume: 65, Issue:5 Topics: Aged; Antineoplastic Agents; Benzodiazepinones; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Tolerance; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Melanoma; Middle Aged; Ovarian Neoplasms; Pyrroles; Urinary Bladder Neoplasms	2010
Semiquantitative analysis of dynamic contrast enhanced MRI in cancer patients: Variability and changes in tumor tissue over time. Journal of magnetic resonance imaging : JMRI, 2004, Volume: 20, Issue:1 Topics: Angiogenesis Inhibitors; Colonic Neoplasms; Contrast Media; Gadolinium DTPA; Humans; Indoles; Liver; Liver Neoplasms; Magnetic Resonance Imaging; Melanoma; Mesothelioma; Muscle, Skeletal; Protein-Tyrosine Kinases; Pyrroles	2004

Other Studies

90 other study(ies) available for pyrroles and Cancer of Colon

Article	Year
Identification of TRPV4 as a novel target in invasiveness of colorectal cancer. BMC cancer, 2021, Nov-23, Volume: 21, Issue:1 Topics: Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Epithelial-Mesenchymal Transition; Female; HCT116 Cells; Humans; Immunohistochemistry; Male; Middle Aged; Morpholines; Neoplasm Invasiveness; Neoplasm Metastasis; Proto-Oncogene Proteins c-akt; Pyrroles; Rectal Neoplasms; RNA, Small Interfering; Transfection; TRPV Cation Channels; Zinc Finger E-box-Binding Homeobox 1	2021
TR1801-ADC: a highly potent cMet antibody-drug conjugate with high activity in patient-derived xenograft models of solid tumors. Molecular oncology, 2020, Volume: 14, Issue:1 Topics: Animals; Antineoplastic Agents; Benzodiazepines; Biliary Tract Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; Humans; Immunoconjugates; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasms; Oncogenes; Proto-Oncogene Proteins c-met; Pyrroles; Rats; Rats, Sprague-Dawley; Stomach Neoplasms; Tissue Array Analysis; Xenograft Model Antitumor Assays	2020
IGF-1R inhibition induces MEK phosphorylation to promote survival in colon carcinomas. Signal transduction and targeted therapy, 2020, 08-26, Volume: 5, Issue:1 Topics: Animals; Apoptosis; Carcinoma; Cell Line, Tumor; Cell Proliferation; Cell Survival; Class I Phosphatidylinositol 3-Kinases; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Kinase 1; Mice; Mitogen-Activated Protein Kinase Kinases; Phosphorylation; Proto-Oncogene Proteins p21(ras); Pyrazoles; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Ribosomal Protein S6 Kinases, 70-kDa; Signal Transduction; Triazines; Xenograft Model Antitumor Assays	2020
Novel pyrrolopyrimidine derivatives induce p53-independent apoptosis via the mitochondrial pathway in colon cancer cells. Chemico-biological interactions, 2020, Oct-01, Volume: 330 Topics: Apoptosis; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Colonic Neoplasms; Gene Knockout Techniques; HCT116 Cells; Humans; Mitochondria; Pyrimidines; Pyrroles; Tumor Suppressor Protein p53	2020
A novel approach for monitoring TGF-β signaling in vivo in colon cancer. Carcinogenesis, 2021, 04-30, Volume: 42, Issue:4 Topics: Animals; Benzamides; Carcinogenesis; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dioxoles; Disease Models, Animal; Humans; Mice; Protein Kinase Inhibitors; Pyrazoles; Pyrroles; Receptors, Transforming Growth Factor beta; Signal Transduction; Transforming Growth Factor beta	2021
Berberine regulates the Notch1/PTEN/PI3K/AKT/mTOR pathway and acts synergistically with 17-AAG and SAHA in SW480 colon cancer cells. Pharmaceutical biology, 2021, Volume: 59, Issue:1 Topics: A549 Cells; Antineoplastic Agents; Benzoquinones; Berberine; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Synergism; HCT116 Cells; Humans; Lactams, Macrocyclic; MCF-7 Cells; Nylons; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Proto-Oncogene Proteins c-akt; PTEN Phosphohydrolase; Pyrroles; Receptor, Notch1; Signal Transduction; THP-1 Cells; TOR Serine-Threonine Kinases	2021
Inhibition of Hematopoietic Cell Kinase Activity Suppresses Myeloid Cell-Mediated Colon Cancer Progression. Cancer cell, 2017, 04-10, Volume: 31, Issue:4 Topics: Animals; Colonic Neoplasms; Colorectal Neoplasms; Female; Gene Expression Regulation, Neoplastic; Humans; Macrophage Activation; Mice, Inbred C57BL; Mice, Knockout; Proto-Oncogene Proteins c-hck; Pyrimidines; Pyrroles; Signal Transduction; STAT3 Transcription Factor; Stromal Cells; Xenograft Model Antitumor Assays	2017
Wnt pathway activator TWS119 enhances the proliferation and cytolytic activity of human γδT cells against colon cancer. Experimental cell research, 2018, 01-01, Volume: 362, Issue:1 Topics: Animals; Cell Proliferation; Cells, Cultured; Colonic Neoplasms; Cytotoxicity, Immunologic; Female; HCT116 Cells; Humans; Immunotherapy, Adoptive; Intraepithelial Lymphocytes; Mice; Mice, Inbred BALB C; Mice, Nude; Pyrimidines; Pyrroles; Up-Regulation; Wnt Signaling Pathway; Xenograft Model Antitumor Assays	2018
VEGF pathway-targeting drugs induce evasive adaptation by activation of neuropilin-1/cMet in colon cancer cells. International journal of oncology, 2018, Volume: 52, Issue:4 Topics: Bevacizumab; Cell Movement; Colonic Neoplasms; Drug Resistance, Neoplasm; HCT116 Cells; Humans; Indoles; Neoplasm Invasiveness; Neuropilin-1; Proto-Oncogene Proteins c-met; Pyrroles; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A	2018
Modulating the Tumor Microenvironment via Oncolytic Viruses and CSF-1R Inhibition Synergistically Enhances Anti-PD-1 Immunotherapy. Molecular therapy : the journal of the American Society of Gene Therapy, 2019, 01-02, Volume: 27, Issue:1 Topics: Aminopyridines; Animals; B7-H1 Antigen; CD8-Positive T-Lymphocytes; Colonic Neoplasms; Female; Flow Cytometry; Humans; Immunotherapy; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Oncolytic Viruses; Programmed Cell Death 1 Receptor; Pyrroles; Receptor, Macrophage Colony-Stimulating Factor; Tumor Microenvironment	2019
[Pexidartinib inhibits the aggregation of monocytes into tumor microenvironment and reduces the number of M2 tumor-associated macrophages]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology, 2019, Volume: 35, Issue:4 Topics: Aminopyridines; Animals; Cell Line, Tumor; Colonic Neoplasms; Flow Cytometry; Leukocytes, Mononuclear; Macrophages; Mice; Monocytes; Pyrroles; Tumor Microenvironment	2019
Impact of dihydropyrrol derivative on the normal colonic mucosa of DMH-induced colon cancer rats compared with 5-fluorouracil. Experimental oncology, 2013, Volume: 35, Issue:1 Topics: Animals; Antineoplastic Agents; Benzothiazoles; Cell Proliferation; Cell Transformation, Neoplastic; Colonic Neoplasms; Dimethylhydrazines; Fluorouracil; Intestinal Mucosa; Male; Pyrroles; Pyrrolidinones; Rats; Rats, Wistar	2013
Multitargeted low-dose GLAD combination chemoprevention: a novel and promising approach to combat colon carcinogenesis. Neoplasia (New York, N.Y.), 2013, Volume: 15, Issue:5 Topics: Adenomatous Polyps; Animals; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Carcinogenesis; Cell Proliferation; Chemoprevention; Colon; Colonic Neoplasms; Cytokines; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Eflornithine; Female; Gefitinib; Heptanoic Acids; Intestine, Small; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Targeted Therapy; Pyrroles; Quinazolines	2013
Inhibition of late-stage autophagy synergistically enhances pyrrolo-1,5-benzoxazepine-6-induced apoptotic cell death in human colon cancer cells. International journal of oncology, 2013, Volume: 43, Issue:3 Topics: Adenocarcinoma; Animals; Apoptosis; Autophagy; Caspases; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Synergism; Humans; Lysosomes; Macrolides; Mice; Microtubule-Associated Proteins; Oxazepines; Pyrroles	2013
Gamma-secretase inhibition attenuates oxaliplatin-induced apoptosis through increased Mcl-1 and/or Bcl-xL in human colon cancer cells. Apoptosis : an international journal on programmed cell death, 2013, Volume: 18, Issue:10 Topics: Adenocarcinoma; Amyloid Precursor Protein Secretases; Antineoplastic Agents; Apoptosis; bcl-X Protein; Cell Line, Tumor; Colonic Neoplasms; Cyclic S-Oxides; Drug Synergism; Humans; Indoles; Myeloid Cell Leukemia Sequence 1 Protein; Organoplatinum Compounds; Oxaliplatin; Pyrroles; RNA, Small Interfering; Signal Transduction; Thiadiazoles	2013
[Potential cytostatic effect of the maleimide derivative 1-(4-Cl-benzyl)-3-Cl-4-(CF3-phenylamino)-1-H-pyrrol-2,5-dione]. Eksperimental'naia i klinicheskaia farmakologiia, 2013, Volume: 76, Issue:8 Topics: Aniline Compounds; Animals; Antineoplastic Agents; Colonic Neoplasms; Cytotoxins; Dimenhydrinate; Drug Screening Assays, Antitumor; Humans; Linoleic Acids; Male; Maleimides; Polyunsaturated Alkamides; Pyrroles; Rats	2013
Longitudinal monitoring of tumor antiangiogenic therapy with near-infrared fluorophore-labeled agents targeted to integrin αvβ3 and vascular endothelial growth factor. European journal of nuclear medicine and molecular imaging, 2014, Volume: 41, Issue:7 Topics: Animals; Colonic Neoplasms; Fluorescent Dyes; Glioblastoma; HT29 Cells; Humans; Indoles; Infrared Rays; Integrin alphaVbeta3; Longitudinal Studies; Mice; Molecular Targeted Therapy; Neovascularization, Pathologic; Optical Imaging; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A	2014
Sunitinib mesylate inhibits proliferation of human colonic stromal fibroblasts in vitro and in vivo. Journal of Zhejiang University. Science. B, 2014, Volume: 15, Issue:8 Topics: Animals; Antineoplastic Agents; Becaplermin; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Colon; Colonic Neoplasms; Fibroblasts; Fluorouracil; Humans; Indoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-sis; Pyrroles; Receptor, Platelet-Derived Growth Factor alpha; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Stromal Cells; Sunitinib; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays	2014
Localization of sunitinib in in vivo animal and in vitro experimental models by MALDI mass spectrometry imaging. Analytical and bioanalytical chemistry, 2015, Volume: 407, Issue:8 Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Colonic Neoplasms; Female; Humans; Indoles; Mice; Mice, Inbred BALB C; Molecular Imaging; Pyrroles; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Sunitinib	2015
The BH3-mimetic obatoclax reduces HIF-1α levels and HIF-1 transcriptional activity and sensitizes hypoxic colon adenocarcinoma cells to 5-fluorouracil. Cancer letters, 2015, Aug-10, Volume: 364, Issue:2 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Hypoxia; Cell Proliferation; Colonic Neoplasms; Down-Regulation; Drug Synergism; Fluorouracil; HCT116 Cells; HT29 Cells; Humans; Hypoxia-Inducible Factor 1; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Pyrroles; Transcriptional Activation	2015
Investigation of the Lack of Angiogenesis in the Formation of Lymph Node Metastases. Journal of the National Cancer Institute, 2015, Volume: 107, Issue:9 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Bevacizumab; Colonic Neoplasms; Head and Neck Neoplasms; Humans; Indoles; Lymph Nodes; Lymphatic Metastasis; Mice; Neovascularization, Pathologic; Pyrroles; Sunitinib	2015
Mechanisms of SU5416, an inhibitor of vascular endothelial growth factor receptor, as a radiosensitizer for colon cancer cells. Oncology reports, 2016, Volume: 36, Issue:2 Topics: Adenocarcinoma; Aging; Antineoplastic Agents; Apoptosis; beta-Galactosidase; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; DNA Repair; HCT116 Cells; HT29 Cells; Humans; Indoles; Neoplasm Invasiveness; Pyrroles; Radiation Tolerance; Radiation-Sensitizing Agents; Reactive Oxygen Species; Receptors, Vascular Endothelial Growth Factor	2016
Alternative scheduling of pulsatile, high dose sunitinib efficiently suppresses tumor growth. Journal of experimental & clinical cancer research : CR, 2016, 09-07, Volume: 35, Issue:1 Topics: Animals; Antineoplastic Agents; Autophagy; Caspases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chick Embryo; Chorioallantoic Membrane; Colonic Neoplasms; HT29 Cells; Humans; Indoles; Pulse Therapy, Drug; Pyrroles; Sunitinib; Xenograft Model Antitumor Assays	2016
Antiangiogenic cancer therapy using tumor vasculature-targeted liposomes encapsulating 3-(3,5-dimethyl-1H-pyrrol-2-ylmethylene)-1,3-dihydro-indol-2-one, SU5416. Cancer letters, 2008, Nov-08, Volume: 270, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Compounding; Drug Stability; Endothelial Cells; Hemolysis; Humans; Indoles; Lipids; Liposomes; Male; Mice; Mice, Inbred BALB C; Oligopeptides; Particle Size; Pyrroles; Solubility; Time Factors; Vascular Endothelial Growth Factor A	2008
[Effect of Endostatin and SU6668 combined with 5-FU on human colon cancer xenograft in nude mice]. Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery, 2008, Volume: 11, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Colonic Neoplasms; Endostatins; Fluorouracil; Humans; Indoles; Lymphatic Metastasis; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neovascularization, Pathologic; Oxindoles; Propionates; Pyrroles	2008
TSU68 prevents liver metastasis of colon cancer xenografts by modulating the premetastatic niche. Cancer research, 2008, Dec-01, Volume: 68, Issue:23 Topics: Animals; Cell Movement; Chemokine CXCL1; Colonic Neoplasms; Gene Expression Profiling; Humans; Indoles; Interleukin-12 Subunit p40; Liver; Liver Neoplasms, Experimental; Male; Mice; Mice, Inbred BALB C; Neutrophils; Oligonucleotide Array Sequence Analysis; Oxindoles; Propionates; Pyrroles; Receptors, Interleukin-8B; RNA, Messenger; Xenograft Model Antitumor Assays	2008
Targeting transforming growth factor-beta signaling in liver metastasis of colon cancer. Cancer letters, 2009, May-08, Volume: 277, Issue:1 Topics: Animals; Cell Line, Tumor; Cell Movement; Colonic Neoplasms; Genes, ras; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Mutation; Neoplasm Invasiveness; Pyrazoles; Pyrroles; Signal Transduction; Smad Proteins; Transforming Growth Factor beta	2009
The novel role of tyrosine kinase inhibitor in the reversal of immune suppression and modulation of tumor microenvironment for immune-based cancer therapies. Cancer research, 2009, Mar-15, Volume: 69, Issue:6 Topics: Amino Acid Sequence; Animals; Carcinoma, Lewis Lung; Colonic Neoplasms; Indoles; Lymphocyte Activation; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Myeloid Cells; Protein Kinase Inhibitors; Pyrroles; Sunitinib; T-Lymphocytes, Regulatory	2009
Inhibition of tyrosine kinase receptors by SU6668 promotes abnormal stromal development at the periphery of carcinomas. British journal of cancer, 2009, May-19, Volume: 100, Issue:10 Topics: Animals; Carcinoma; Cell Proliferation; Colonic Neoplasms; Disease Progression; HT29 Cells; Humans; Indoles; Magnetic Resonance Imaging; Mice; Mice, Nude; Neovascularization, Pathologic; Oxindoles; Propionates; Pyrroles; Receptor Protein-Tyrosine Kinases; Stromal Cells; Up-Regulation; Xenograft Model Antitumor Assays	2009
Targeting both HIF-1 and HIF-2 in human colon cancer cells improves tumor response to sunitinib treatment. Molecular cancer therapeutics, 2009, Volume: 8, Issue:5 Topics: Animals; Antineoplastic Agents; Basic Helix-Loop-Helix Transcription Factors; Cell Line, Tumor; Colonic Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Gene Knockout Techniques; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Indoles; Mice; Mice, Nude; Neovascularization, Pathologic; Pyrroles; Sunitinib; Xenograft Model Antitumor Assays	2009
Chemopreventive efficacy of pronyl-lysine on lipid peroxidation and antioxidant status in rat colon carcinogenesis. Fundamental & clinical pharmacology, 2009, Volume: 23, Issue:3 Topics: 1,2-Dimethylhydrazine; Animals; Anticarcinogenic Agents; Antioxidants; Cecum; Colon; Colonic Neoplasms; Lipid Peroxidation; Lysine; Male; Pyrroles; Rats; Rats, Wistar	2009
Synergistic actions of atorvastatin with gamma-tocotrienol and celecoxib against human colon cancer HT29 and HCT116 cells. International journal of cancer, 2010, Feb-15, Volume: 126, Issue:4 Topics: Atorvastatin; Celecoxib; Cell Cycle; Cell Division; Cell Line, Tumor; Chromans; Colonic Neoplasms; Cyclooxygenase 2 Inhibitors; Drug Synergism; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Mevalonic Acid; Polyisoprenyl Phosphates; Pyrazoles; Pyrroles; Sulfonamides; Vitamin E	2010
Autophagy can contribute to cell death when combining targeted therapy. Cancer biology & therapy, 2009, Volume: 8, Issue:21 Topics: Antineoplastic Combined Chemotherapy Protocols; Autophagy; Cell Death; Colonic Neoplasms; HCT116 Cells; Humans; Indoles; Lapatinib; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Quinazolines	2009
TSU68, an antiangiogenic receptor tyrosine kinase inhibitor, induces tumor vascular normalization in a human cancer xenograft nude mouse model. Surgery today, 2009, Volume: 39, Issue:12 Topics: Angiogenesis Inhibitors; Animals; Colon; Colonic Neoplasms; Disease Models, Animal; Drug Delivery Systems; Humans; Indoles; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neovascularization, Pathologic; Neovascularization, Physiologic; Oxindoles; Propionates; Pyrroles; Receptors, Fibroblast Growth Factor; Receptors, Platelet-Derived Growth Factor; Sensitivity and Specificity; Transplantation, Heterologous; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays	2009
Synergistic antitumor effect of TRAIL in combination with sunitinib in vitro and in vivo. Cancer letters, 2010, Jul-28, Volume: 293, Issue:2 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Drug Screening Assays, Antitumor; Drug Synergism; Humans; Indoles; Lung Neoplasms; Male; Mice; Mice, Nude; Pyrroles; Sunitinib; TNF-Related Apoptosis-Inducing Ligand; Xenograft Model Antitumor Assays	2010
Synthesis of new pyrrolo[2,3-d]pyrimidine derivatives and evaluation of their activities against human colon cancer cell lines. European journal of medicinal chemistry, 2010, Volume: 45, Issue:4 Topics: Apoptosis; Colonic Neoplasms; Dose-Response Relationship, Drug; HCT116 Cells; Humans; Inhibitory Concentration 50; Magnetic Resonance Spectroscopy; Pyrimidines; Pyrroles; Spectrometry, Mass, Electrospray Ionization	2010
Atorvastatin induces apoptosis in vitro and slows growth of tumor xenografts but not polyp formation in MIN mice. Digestive diseases and sciences, 2010, Volume: 55, Issue:11 Topics: Animals; Apoptosis; Atorvastatin; Colonic Neoplasms; Colonic Polyps; Disease Models, Animal; DNA Fragmentation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Mice, Nude; Pyrroles; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2010
Synthesis, DNA-binding ability and anticancer activity of benzothiazole/benzoxazole-pyrrolo[2,1-c][1,4]benzodiazepine conjugates. Bioorganic & medicinal chemistry, 2010, Jul-01, Volume: 18, Issue:13 Topics: Animals; Antineoplastic Agents; Apoptosis; Benzodiazepines; Benzothiazoles; Benzoxazoles; Binding Sites; Cell Line, Tumor; Colonic Neoplasms; DNA; G1 Phase; Humans; Mice; Molecular Dynamics Simulation; Nucleic Acid Denaturation; Pyrroles; Resting Phase, Cell Cycle; Software; Transplantation, Heterologous	2010
Renal cell carcinoma and acute promyelocytic leukemia: a nonrandom association? American journal of hematology, 2010, Volume: 85, Issue:10 Topics: Adenocarcinoma; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Renal Cell; Colonic Neoplasms; Colonic Polyps; Cytarabine; Daunorubicin; Doxorubicin; Female; Humans; Idarubicin; Indoles; Kidney Neoplasms; Leukemia, Promyelocytic, Acute; Lung Neoplasms; Male; Mercaptopurine; Methotrexate; Middle Aged; Neoplasms, Second Primary; Pyrroles; Remission Induction; Sunitinib; Time Factors; Tretinoin	2010
Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL. Analytical cellular pathology (Amsterdam), 2010, Volume: 33, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Separation; Colonic Neoplasms; Enzyme Activation; Flow Cytometry; Humans; Immunoprecipitation; Microscopy, Fluorescence; Phosphatidylinositol 3-Kinases; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand	2010
Novel pyrrolo[2,1-f][1,2,4]triazin-4-amines: Dual inhibitors of EGFR and HER2 protein tyrosine kinases. Bioorganic & medicinal chemistry letters, 2011, Jan-15, Volume: 21, Issue:2 Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Colonic Neoplasms; ErbB Receptors; Humans; Male; Mice; Mice, Inbred BALB C; Models, Molecular; Neoplasms; Protein-Tyrosine Kinases; Pyrroles; Receptor, ErbB-2; Stomach Neoplasms; Triazines; Xenograft Model Antitumor Assays	2011
Inhibition of IGF-1R-dependent PI3K activation sensitizes colon cancer cells specifically to DR5-mediated apoptosis but not to rhTRAIL. Cellular oncology (Dordrecht), 2011, Volume: 34, Issue:3 Topics: Antibodies, Neoplasm; Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Colonic Neoplasms; Death Domain Receptor Signaling Adaptor Proteins; Enzyme Activation; Humans; Models, Biological; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Receptors, TNF-Related Apoptosis-Inducing Ligand; Recombinant Proteins; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand	2011
Design, synthesis and biological evaluation of novel 4-thiazolidinones containing indolin-2-one moiety as potential antitumor agent. European journal of medicinal chemistry, 2011, Volume: 46, Issue:8 Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; Female; Fibroblasts; Humans; Indoles; Inhibitory Concentration 50; Liver Neoplasms; Lung Neoplasms; Pyrroles; Sunitinib; Thiazolidines	2011
Consequence of dose scheduling of sunitinib on host immune response elements and vaccine combination therapy. International journal of cancer, 2012, Apr-15, Volume: 130, Issue:8 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cancer Vaccines; Carcinoembryonic Antigen; CD8-Positive T-Lymphocytes; Cell Line, Tumor; Colonic Neoplasms; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Flow Cytometry; Humans; Immune System; Indoles; Mice; Mice, Inbred C57BL; Mice, Transgenic; Neoplasms, Experimental; Pyrroles; Receptors, Platelet-Derived Growth Factor; Signal Transduction; Sunitinib; T-Lymphocytes, Regulatory; Treatment Outcome	2012
Combination of atorvastatin with sulindac or naproxen profoundly inhibits colonic adenocarcinomas by suppressing the p65/β-catenin/cyclin D1 signaling pathway in rats. Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:11 Topics: Adenocarcinoma; Animals; Anti-Inflammatory Agents, Non-Steroidal; Anticholesteremic Agents; Antineoplastic Combined Chemotherapy Protocols; Atorvastatin; Azoxymethane; beta Catenin; Carcinogens; Colonic Neoplasms; Cyclin D1; eIF-2 Kinase; Enzyme-Linked Immunosorbent Assay; Heptanoic Acids; Immunoenzyme Techniques; Interleukin-4; Male; Naproxen; Nitric Oxide Synthase Type II; Pyrroles; Rats; Rats, Inbred F344; Signal Transduction; Sulindac; Tumor Necrosis Factor-alpha	2011
[Adverse effects of new oncologic therapies]. Praxis, 2011, Jul-27, Volume: 100, Issue:15 Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Benzenesulfonates; Bevacizumab; Cetuximab; Colonic Neoplasms; Diagnosis, Differential; Dose-Response Relationship, Drug; Drug Delivery Systems; Drug Eruptions; ErbB Receptors; Erlotinib Hydrochloride; Everolimus; Facial Dermatoses; Humans; Indoles; Liver Neoplasms; Male; Middle Aged; Neoplasms; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Quinazolines; Sirolimus; Sorafenib; Sunitinib; Trastuzumab	2011
Chemoprevention of colon and small intestinal tumorigenesis in APC(Min/+) mice by licofelone, a novel dual 5-LOX/COX inhibitor: potential implications for human colon cancer prevention. Cancer prevention research (Philadelphia, Pa.), 2011, Volume: 4, Issue:12 Topics: Adenomatous Polyposis Coli Protein; Animals; Apoptosis; Arachidonate 5-Lipoxygenase; Blotting, Western; Cell Proliferation; Colonic Neoplasms; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Humans; Intestinal Neoplasms; Male; Mice; Mice, Inbred C57BL; Pyrroles; Real-Time Polymerase Chain Reaction; RNA, Messenger	2011
Chemoprevention of mouse lung and colon tumors by suberoylanilide hydroxamic acid and atorvastatin. International journal of cancer, 2012, Sep-15, Volume: 131, Issue:6 Topics: Animals; Atorvastatin; Colonic Neoplasms; Dimethylhydrazines; Female; Heptanoic Acids; Histone Deacetylase Inhibitors; Hydroxamic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lung Neoplasms; Mice; Nitrosamines; Pyrroles; RNA, Messenger; Urethane; Vorinostat	2012
The decrease of cell membrane fluidity by the non-steroidal anti-inflammatory drug Licofelone inhibits epidermal growth factor receptor signalling and triggers apoptosis in HCA-7 colon cancer cells. Cancer letters, 2012, Aug-28, Volume: 321, Issue:2 Topics: Anti-Inflammatory Agents, Non-Steroidal; Apoptosis; Blotting, Western; Cell Line, Tumor; Cell Membrane; Cell Survival; Colonic Neoplasms; ErbB Receptors; Fluorescent Antibody Technique; Humans; Membrane Fluidity; Mitogen-Activated Protein Kinases; Pyrroles; Signal Transduction	2012
Deleterious effects of high concentrations of (-)-epigallocatechin-3-gallate and atorvastatin in mice with colon inflammation. Nutrition and cancer, 2012, Volume: 64, Issue:6 Topics: Animals; Atorvastatin; Azoxymethane; Catechin; Colitis; Colon; Colonic Neoplasms; Dextran Sulfate; Dinoprostone; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Gastrointestinal Hemorrhage; Heptanoic Acids; Leukotriene B4; Mice; Mice, Inbred C57BL; Mice, Inbred Strains; Pyrroles; Rectum; Weight Loss	2012
C1B domain peptide of protein kinase Cγ significantly suppresses growth of human colon cancer cells in vitro and in an in vivo mouse xenograft model through induction of cell cycle arrest and apoptosis. Cancer biology & therapy, 2012, Volume: 13, Issue:10 Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Female; Humans; Indoles; Injections, Intralesional; Isoenzymes; Mice; Mice, SCID; Peptide Fragments; Peptides; Phosphorylation; Protein Interaction Domains and Motifs; Protein Kinase C; Pyrroles; Serine; Tumor Burden; Tumor Suppressor Protein p53; Xenograft Model Antitumor Assays	2012
Decrease in blood miR-296 predicts chemotherapy resistance and poor clinical outcome in patients receiving systemic chemotherapy for metastatic colon cancer. International journal of colorectal disease, 2013, Volume: 28, Issue:6 Topics: Capecitabine; Colonic Neoplasms; Deoxycytidine; Disease Progression; Drug Resistance, Neoplasm; Fluorouracil; Humans; Indoles; MicroRNAs; Neoplasm Metastasis; Pyrroles; Sunitinib; Treatment Outcome	2013
The multi-targeted kinase inhibitor sunitinib induces apoptosis in colon cancer cells via PUMA. PloS one, 2012, Volume: 7, Issue:8 Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Cell Line, Tumor; Chromatin Immunoprecipitation; Colonic Neoplasms; DNA Primers; Forkhead Box Protein O3; Forkhead Transcription Factors; Gene Expression Regulation, Neoplastic; Histological Techniques; Humans; In Situ Nick-End Labeling; Indoles; Luciferases; Oncogene Protein v-akt; Proto-Oncogene Proteins; Pyrroles; Real-Time Polymerase Chain Reaction; Reverse Transcriptase Polymerase Chain Reaction; Sunitinib	2012
VEGFA-VEGFR pathway blockade inhibits tumor-induced regulatory T-cell proliferation in colorectal cancer. Cancer research, 2013, Jan-15, Volume: 73, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Cell Count; Cell Line, Tumor; Cell Proliferation; Colonic Neoplasms; Colorectal Neoplasms; Female; Humans; Indoles; Mice; Mice, Inbred BALB C; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sunitinib; T-Lymphocytes, Regulatory; Tumor Escape; Vascular Endothelial Growth Factor A	2013
Deeper penetration into tumor tissues and enhanced in vivo antitumor activity of liposomal paclitaxel by pretreatment with angiogenesis inhibitor SU5416. Molecular pharmaceutics, 2012, Dec-03, Volume: 9, Issue:12 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Phytogenic; Colonic Neoplasms; Humans; Immunoenzyme Techniques; Indoles; Liposomes; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Paclitaxel; Pericytes; Polyethylene Glycols; Pyrroles; Solubility; Tumor Cells, Cultured; Vascular Endothelial Growth Factor Receptor-2	2012
Autophagy, cell death and sustained senescence arrest in B16/F10 melanoma cells and HCT-116 colon carcinoma cells in response to the novel microtubule poison, JG-03-14. Cancer chemotherapy and pharmacology, 2013, Volume: 71, Issue:2 Topics: Animals; Apoptosis; Autophagy; Cellular Senescence; Colonic Neoplasms; HCT116 Cells; Humans; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Microtubules; Peripheral Nervous System Diseases; Pyrroles	2013
Salinosporamide A: a highly cytotoxic proteasome inhibitor from a novel microbial source, a marine bacterium of the new genus salinospora. Angewandte Chemie (International ed. in English), 2003, Jan-20, Volume: 42, Issue:3 Topics: Actinomycetales; Adenocarcinoma; Colonic Neoplasms; Crystallography, X-Ray; Cysteine Endopeptidases; Humans; Inhibitory Concentration 50; Lactones; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Multienzyme Complexes; Protease Inhibitors; Proteasome Endopeptidase Complex; Pyrroles; Tumor Cells, Cultured	2003
Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells. British journal of cancer, 2003, Oct-20, Volume: 89, Issue:8 Topics: Adaptor Proteins, Signal Transducing; Adenocarcinoma; Animals; Antineoplastic Agents; Base Pair Mismatch; Carrier Proteins; Cell Death; Colonic Neoplasms; Distamycins; DNA Repair; DNA-Binding Proteins; Drug Resistance, Neoplasm; Fibroblasts; Guanidines; Humans; Mice; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neoplasm Proteins; Nitrogen Mustard Compounds; Nuclear Proteins; Proto-Oncogene Proteins; Pyrroles; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2003
Enhancement of in vivo antitumor activity of classical anticancer agents by combination with the new, glutathione-interacting DNA minor groove-binder, brostallicin. Clinical cancer research : an official journal of the American Association for Cancer Research, 2003, Nov-01, Volume: 9, Issue:14 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Colonic Neoplasms; DNA; Doxorubicin; Female; Glutathione; Glutathione Transferase; Guanidines; Irinotecan; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred DBA; Mice, Nude; Pyrroles; Transplantation, Heterologous	2003
In vivo assessment of antiangiogenic activity of SU6668 in an experimental colon carcinoma model. Clinical cancer research : an official journal of the American Association for Cancer Research, 2004, Jan-15, Volume: 10, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Cell Line, Tumor; Colonic Neoplasms; Contrast Media; Humans; Immunohistochemistry; Indoles; Magnetic Resonance Imaging; Mice; Mice, Nude; Models, Statistical; Neoplasm Transplantation; Neovascularization, Pathologic; Oxindoles; Permeability; Platelet Endothelial Cell Adhesion Molecule-1; Propionates; Protein-Tyrosine Kinases; Pyrroles; Time Factors	2004
Gene expression profiling of human colon xenograft tumors following treatment with SU11248, a multitargeted tyrosine kinase inhibitor. Oncogene, 2004, Feb-26, Volume: 23, Issue:8 Topics: Animals; Biomarkers; Cadherins; Cell Line, Tumor; Colonic Neoplasms; Enzyme Inhibitors; Feasibility Studies; Female; Gene Expression Profiling; Humans; Immunohistochemistry; Indoles; Mice; Mice, Nude; Neoplasm Transplantation; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib; Transplantation, Heterologous	2004
Protein kinase C (PKC) betaII induces cell invasion through a Ras/Mek-, PKC iota/Rac 1-dependent signaling pathway. The Journal of biological chemistry, 2004, May-21, Volume: 279, Issue:21 Topics: Animals; Apoptosis Regulatory Proteins; Butadienes; Carrier Proteins; Cell Line; Colonic Neoplasms; Cyclooxygenase 2; Enzyme Activation; Enzyme Inhibitors; Genes, Dominant; Genetic Predisposition to Disease; Glutathione Transferase; GTP-Binding Proteins; Humans; Intestinal Mucosa; Intracellular Signaling Peptides and Proteins; Isoenzymes; MAP Kinase Kinase Kinase 1; MAP Kinase Kinase Kinases; Membrane Proteins; Mesylates; Models, Biological; Mutation; Neoplasm Invasiveness; Nitriles; p21-Activated Kinases; Phenotype; Prostaglandin-Endoperoxide Synthases; Protein Kinase C; Protein Kinase C beta; Protein Serine-Threonine Kinases; Pyrroles; rac1 GTP-Binding Protein; ras Proteins; Rats; Retroviridae; Signal Transduction; Transfection	2004
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy. Oncogene, 2004, May-27, Volume: 23, Issue:25 Topics: Amino Acid Chloromethyl Ketones; Aneuploidy; Antibiotics, Antineoplastic; Apoptosis; Azepines; Caspase 2; Caspase 3; Caspase Inhibitors; Caspases; CD4 Antigens; Cell Division; Cell Fusion; Cell Line, Tumor; Cell Transformation, Neoplastic; Centrosome; Checkpoint Kinase 2; Colonic Neoplasms; Cysteine Proteinase Inhibitors; DNA Damage; Doxorubicin; Genes, env; Giant Cells; HeLa Cells; Humans; Intracellular Membranes; Metaphase; Mitochondria; Mitosis; Models, Biological; Protein Serine-Threonine Kinases; Pyrroles; RNA Interference; Transfection	2004
Red wine polyphenolics suppress the secretion and the synthesis of Apo B48 from human intestinal CaCo-2 cells. BioFactors (Oxford, England), 2004, Volume: 22, Issue:1-4 Topics: Apolipoprotein B-48; Apolipoproteins B; Atorvastatin; Cell Line, Tumor; Colonic Neoplasms; Flavonoids; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Phenols; Polyphenols; Pyrroles; Wine	2004
Angiogenesis inhibitor Z24 induces endothelial cell apoptosis and suppresses tumor growth and metastasis. Journal of pharmacological sciences, 2005, Volume: 97, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Line; Cell Line, Tumor; Colonic Neoplasms; Endothelium, Vascular; Humans; Lung Neoplasms; Male; Mesylates; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Neovascularization, Pathologic; Pyrroles; Transplantation, Heterologous	2005
Total synthesis of ningalin D. Journal of the American Chemical Society, 2005, Aug-03, Volume: 127, Issue:30 Topics: Animals; Biphenyl Compounds; Colonic Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HCT116 Cells; Humans; Leukemia L1210; Mice; Porifera; Pyrroles; Quinones	2005
Influence of P-glycoprotein expression on in vitro cytotoxicity and in vivo antitumour activity of the novel pyrrolobenzodiazepine dimer SJG-136. European journal of cancer (Oxford, England : 1990), 2005, Volume: 41, Issue:12 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Benzodiazepinones; Cell Line, Tumor; Colonic Neoplasms; Drug Combinations; Humans; Immunoblotting; Inhibitory Concentration 50; Mice; Mice, Inbred C57BL; Pyrroles; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Transplantation, Heterologous; Verapamil	2005
TSU-68 (SU6668) inhibits local tumor growth and liver metastasis of human colon cancer xenografts via anti-angiogenesis. Oncology reports, 2005, Volume: 14, Issue:3 Topics: Administration, Oral; Animals; Cell Line, Tumor; Colonic Neoplasms; HT29 Cells; Humans; Immunohistochemistry; Indoles; Ki-67 Antigen; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, SCID; Oxindoles; Platelet Endothelial Cell Adhesion Molecule-1; Propionates; Protein-Tyrosine Kinases; Pyrroles; Treatment Outcome; Xenograft Model Antitumor Assays	2005
Early antiangiogenic activity of SU11248 evaluated in vivo by dynamic contrast-enhanced magnetic resonance imaging in an experimental model of colon carcinoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Aug-15, Volume: 11, Issue:16 Topics: Angiogenesis Inhibitors; Animals; Colonic Neoplasms; Contrast Media; Gadolinium DTPA; HT29 Cells; Humans; Image Enhancement; Indoles; Magnetic Resonance Imaging; Mice; Mice, Nude; Neovascularization, Pathologic; Pyrroles; Reproducibility of Results; Sensitivity and Specificity; Sunitinib; Treatment Outcome; Xenograft Model Antitumor Assays	2005
Cytotoxicity of novel derivatives of the spin trap EMPO. Bioorganic & medicinal chemistry letters, 2006, Volume: 16, Issue:3 Topics: Breast Neoplasms; Cell Death; Colonic Neoplasms; Dose-Response Relationship, Drug; Electron Spin Resonance Spectroscopy; Fibroblasts; Free Radicals; Humans; Lung Neoplasms; Pyrroles; Spin Labels; Spin Trapping; Structure-Activity Relationship; Tumor Cells, Cultured	2006
Synthesis and biological evaluation of novel pyrrolo[2,1-c][1,4]benzodiazepine prodrugs for use in antibody-directed enzyme prodrug therapy. Bioorganic & medicinal chemistry letters, 2006, Jan-15, Volume: 16, Issue:2 Topics: Antibodies; Antigens, Neoplasm; Antineoplastic Agents; Benzodiazepines; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Drug Design; Drug Screening Assays, Antitumor; gamma-Glutamyl Hydrolase; Humans; Inhibitory Concentration 50; Molecular Structure; Nitrogen Mustard Compounds; Prodrugs; Pyrroles; Structure-Activity Relationship; Time Factors	2006
Prevention of azoxymethane-induced colon cancer by combination of low doses of atorvastatin, aspirin, and celecoxib in F 344 rats. Cancer research, 2006, Apr-15, Volume: 66, Issue:8 Topics: Animals; Anticarcinogenic Agents; Apoptosis; Aspirin; Atorvastatin; Azoxymethane; Carcinogens; Celecoxib; Cell Growth Processes; Colonic Neoplasms; Dose-Response Relationship, Drug; Heptanoic Acids; Male; Pyrazoles; Pyrroles; Rats; Rats, Inbred F344; Sulfonamides	2006
NPI-0052 enhances tumoricidal response to conventional cancer therapy in a colon cancer model. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Nov-15, Volume: 12, Issue:22 Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Boronic Acids; Bortezomib; Cell Cycle; Colonic Neoplasms; Drug Administration Routes; Drug Synergism; Female; Humans; Lactones; Mice; Mice, Nude; NF-kappa B; Proteasome Endopeptidase Complex; Pyrazines; Pyrroles; Tumor Cells, Cultured; Tumor Necrosis Factor-alpha; Xenograft Model Antitumor Assays	2006
Pathological animal models in the experimental evaluation of tumour microvasculature with magnetic resonance imaging. La Radiologia medica, 2007, Volume: 112, Issue:3 Topics: Adenocarcinoma; Albumins; Angiogenesis Inhibitors; Animals; Antineoplastic Agents, Hormonal; Colonic Neoplasms; Contrast Media; Gadolinium DTPA; Indoles; Magnetic Resonance Imaging; Mammary Neoplasms, Experimental; Microcirculation; Neoplasms, Experimental; Organometallic Compounds; Oxindoles; Propionates; Protein-Tyrosine Kinases; Pyrroles; Rats; Tamoxifen	2007
Licofelone, a dual COX/5-LOX inhibitor, induces apoptosis in HCA-7 colon cancer cells through the mitochondrial pathway independently from its ability to affect the arachidonic acid cascade. Carcinogenesis, 2008, Volume: 29, Issue:2 Topics: Acetates; Apoptosis; Arachidonic Acid; Cell Line, Tumor; Cell Survival; Colonic Neoplasms; Cyclooxygenase Inhibitors; Cytosol; Gene Expression Regulation, Neoplastic; Humans; Lipoxygenase Inhibitors; Membrane Potential, Mitochondrial; Mitochondria; Prostaglandin-Endoperoxide Synthases; Pyrroles	2008
Combination of atorvastatin and celecoxib synergistically induces cell cycle arrest and apoptosis in colon cancer cells. International journal of cancer, 2008, May-01, Volume: 122, Issue:9 Topics: Apoptosis; Atorvastatin; Celecoxib; Cell Cycle; Cell Survival; Colonic Neoplasms; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; G1 Phase; GTP-Binding Proteins; HCT116 Cells; Heptanoic Acids; HT29 Cells; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunoblotting; MAP Kinase Kinase 4; Proto-Oncogene Proteins c-akt; Pyrazoles; Pyrroles; Resting Phase, Cell Cycle; Signal Transduction; Sulfonamides; Time Factors	2008
Aberrant crypt foci and AgNORs as putative biomarkers to evaluate the chemopreventive efficacy of pronyl-lysine in rat colon carcinogenesis. Investigational new drugs, 2008, Volume: 26, Issue:6 Topics: 1,2-Dimethylhydrazine; Administration, Oral; Animals; Anticarcinogenic Agents; Antigens, Nuclear; Antioxidants; Biomarkers, Tumor; Bread; Carcinogens; Cell Proliferation; Colonic Neoplasms; Gene Expression Regulation, Neoplastic; Lysine; Male; Precancerous Conditions; Pyrroles; Random Allocation; Rats; Rats, Wistar	2008
Phosphorylated epidermal growth factor receptor on tumor-associated endothelial cells is a primary target for therapy with tyrosine kinase inhibitors. Neoplasia (New York, N.Y.), 2008, Volume: 10, Issue:5 Topics: Animals; Apoptosis; Blotting, Western; Camptothecin; Cecum; Cell Proliferation; Colonic Neoplasms; Drug Therapy, Combination; Endothelial Cells; Enzyme Inhibitors; ErbB Receptors; Humans; Immunoenzyme Techniques; In Situ Nick-End Labeling; Irinotecan; Lymphatic Metastasis; Male; Mice; Mice, Nude; Necrosis; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, ErbB-2; RNA, Small Interfering; Topoisomerase I Inhibitors; Transforming Growth Factor alpha	2008
Activity of bis-carbamoyloxymethyl derivatives of pyrroles and pyrrolizines against human tumor xenografts in nude mice. Cancer research, 1982, Volume: 42, Issue:6 Topics: Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Small Cell; Cell Line; Colonic Neoplasms; Drug Evaluation, Preclinical; Humans; Lung Neoplasms; Mice; Mice, Nude; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pyrroles; Pyrrolidines; Transplantation, Heterologous	1982
Makaluvamines, marine natural products, are active anti-cancer agents and DNA topo II inhibitors. Anti-cancer drug design, 1993, Volume: 8, Issue:5 Topics: Animals; Antineoplastic Agents; CHO Cells; Colonic Neoplasms; Cricetinae; Drug Screening Assays, Antitumor; Female; Humans; Leukemia, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred Strains; Mice, Nude; Neoplasm Transplantation; Ovarian Neoplasms; Porifera; Pyrroles; Quinones; Topoisomerase II Inhibitors; Tumor Cells, Cultured	1993
Regulation of human Caco-2 intestinal epithelial brush border enzyme activity by cyclic nucleotides. Cancer letters, 1996, Feb-06, Volume: 99, Issue:2 Topics: Adenylyl Cyclase Inhibitors; Alkaline Phosphatase; Alkaloids; Bucladesine; Caco-2 Cells; Carbazoles; Cell Line; Colonic Neoplasms; Cyclic AMP; Cyclic GMP; Dibutyryl Cyclic GMP; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; Drug Synergism; Enzyme Inhibitors; Epithelium; Guanylate Cyclase; Homeostasis; Humans; Indoles; Intestines; Kinetics; Microvilli; Pyrroles	1996
Rapid adhesion and spread of non-adherent colon cancer Colo201 cells induced by the protein kinase inhibitors, K252a and KT5720 and suppression of the adhesion by the immunosuppressants FK506 and cyclosporin A. Cell structure and function, 1998, Volume: 23, Issue:5 Topics: Adenocarcinoma; Carbazoles; Cell Adhesion; Cell Adhesion Molecules; Colonic Neoplasms; Cyclosporine; Cytoskeletal Proteins; Enzyme Inhibitors; Extracellular Matrix; Focal Adhesion Kinase 1; Focal Adhesion Protein-Tyrosine Kinases; Humans; Immunosuppressive Agents; Indole Alkaloids; Indoles; Integrins; Neoplasm Metastasis; Paxillin; Phosphoproteins; Phosphorylation; Protein Kinase C; Protein-Tyrosine Kinases; Pyrroles; Sulfonamides; Tacrolimus; Tumor Cells, Cultured; Tyrosine	1998
The novel cyclopropapyrroloindole(CPI) bisalkylators bearing 3,3'-(1,4-phenylene)diacryloyl group as a linker. Bioorganic & medicinal chemistry letters, 1998, Aug-04, Volume: 8, Issue:15 Topics: Adenocarcinoma; Animals; Antineoplastic Agents, Alkylating; Benzylidene Compounds; Cell Division; Colonic Neoplasms; HeLa Cells; Humans; Mice; Pyrroles; Structure-Activity Relationship	1998
Antiangiogenic therapy targeting the tyrosine kinase receptor for vascular endothelial growth factor receptor inhibits the growth of colon cancer liver metastasis and induces tumor and endothelial cell apoptosis. Cancer research, 1999, Nov-01, Volume: 59, Issue:21 Topics: Animals; Apoptosis; Colonic Neoplasms; Endothelium; Fluorescent Antibody Technique; In Situ Nick-End Labeling; Indoles; Liver Neoplasms; Male; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Pyrroles; Random Allocation; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Tumor Cells, Cultured	1999
Vascular endothelial growth factor in human colon cancer: biology and therapeutic implications. The oncologist, 2000, Volume: 5 Suppl 1 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Division; Colonic Neoplasms; Disease Models, Animal; Endothelial Growth Factors; Endothelium, Vascular; Enzyme Inhibitors; Humans; Indoles; Liver Neoplasms; Lymphokines; Mice; Neoplasm Metastasis; Neovascularization, Pathologic; Prognosis; Protein Isoforms; Protein-Tyrosine Kinases; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Mitogen; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2000
A novel synthetic DNA minor groove binder, MS-247: antitumor activity and cytotoxic mechanism. Cancer chemotherapy and pharmacology, 2000, Volume: 46, Issue:1 Topics: Animals; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Agents, Phytogenic; Benzimidazoles; Cell Survival; Cisplatin; Colonic Neoplasms; DNA; Female; Fluorescent Dyes; Humans; Leukemia L1210; Leukemia P388; Macromolecular Substances; Melanoma, Experimental; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Inbred DBA; Paclitaxel; Pyrroles; Radiation-Sensitizing Agents	2000
Tyrosine kinase inhibition of multiple angiogenic growth factor receptors improves survival in mice bearing colon cancer liver metastases by inhibition of endothelial cell survival mechanisms. Cancer research, 2001, Feb-15, Volume: 61, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Cell Division; Cell Survival; Colonic Neoplasms; Endothelium, Vascular; Indoles; Liver Neoplasms, Experimental; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Oxindoles; Propionates; Pyrroles; Receptor Protein-Tyrosine Kinases; Receptors, Fibroblast Growth Factor; Receptors, Growth Factor; Receptors, Platelet-Derived Growth Factor; Receptors, Vascular Endothelial Growth Factor	2001
Targeted cytotoxic somatostatin analogue AN-238 inhibits somatostatin receptor-positive experimental colon cancers independently of their p53 status. Cancer research, 2002, Feb-01, Volume: 62, Issue:3 Topics: Animals; Antibiotics, Antineoplastic; Colonic Neoplasms; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Doxorubicin; Genes, p53; Humans; Immunoblotting; Immunohistochemistry; Male; Mice; Mice, Nude; Mutation; Proliferating Cell Nuclear Antigen; Pyrroles; Receptors, Somatostatin; RNA, Messenger; Tumor Cells, Cultured; Tumor Suppressor Protein p53	2002
Structure-activity studies of antitumor agents based on pyrrolo[1,2-a]benzimidazoles: new reductive alkylating DNA cleaving agents. Journal of medicinal chemistry, 1991, Volume: 34, Issue:10 Topics: Alkylation; Antineoplastic Agents; Aziridines; Benzimidazoles; Colonic Neoplasms; DNA; Female; Free Radicals; Humans; Molecular Structure; Multiple Myeloma; Ovarian Neoplasms; Oxidation-Reduction; Oxygen; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured	1991
Synthesis and antineoplastic activity of 5-aryl-2,3-dihydropyrrolo[2,1-b]thiazole-6,7-dimethanol 6,7-bis(isopropylcarbamates). Journal of medicinal chemistry, 1988, Volume: 31, Issue:7 Topics: Carbamates; Cell Division; Cell Survival; Chemical Phenomena; Chemistry; Colonic Neoplasms; Humans; Leukemia, Myeloid; Neoplasms; Pyrroles; Structure-Activity Relationship; Thiazoles; Tumor Cells, Cultured	1988