Page last updated: 2024-08-18

pyrroles and Brain Neoplasms

pyrroles has been researched along with Brain Neoplasms in 107 studies

Research

Studies (107)

Timeframe	Studies, this research(%)	All Research%
pre-1990	1 (0.93)	18.7374
1990's	1 (0.93)	18.2507
2000's	18 (16.82)	29.6817
2010's	82 (76.64)	24.3611
2020's	5 (4.67)	2.80

Authors

Authors	Studies
Brahm, CG; de Goeij-de Haas, R; De Witt Hamer, PC; Dekker, H; Henneman, AA; Honeywell, RJ; Hovinga, KE; Jiménez, CR; Knol, JC; Labots, M; Peters, GJ; Pham, TV; Piersma, SR; van Linde, ME; Vandertop, WP; Verheul, HMW	1
Fermi, V; Herold-Mende, C; Regulska, E; Romero-Nieto, C; Rominger, F; Wessling, P; Wolfram, A	1
Adler, S; Aljumaily, R; Antal, JM; Beck, JT; Boccia, RV; Bulat, I; Chiu, VK; Csoszi, T; Domine Gomez, M; Dragnev, KH; Hamm, JT; Hanna, W; Hart, LL; Hoyer, RJ; Hussein, MA; Lai, AY; Lowczak, A; Maglakelidze, M; Malik, RK; Morris, SR; Nikolinakos, P; Owonikoko, TK; Richards, DA; Roberts, PJ; Rocha Lima, CM; Sawrycki, P; Schuster, SR; Sorrentino, JA; Weiss, JM; Yang, Z	1
Bai, R; Biagioni, S; Cavallini, C; Coluccia, A; Coluccia, AML; Da Pozzo, E; Hamel, E; La Regina, G; Liu, T; Martini, C; Mazzoccoli, C; Mazzoni, C; Nalli, M; Orlando, V; Puxeddu, M; Shen, H; Silvestri, R	1
Andreasson, KI; Ceribelli, M; Chen, L; Duveau, DY; Ferrer, M; Geraghty, AC; Ghanem, R; Gillespie, SM; Guha, R; Itkin, Z; Klumpp-Thomas, C; Kreimer, S; Lennon, J; Lin, GL; McKnight, C; Michael, S; Michalowski, AM; Minhas, P; Monje, M; Morris, PJ; Nagaraja, S; Ni, L; Qin, EY; Quezada, M; Raabe, EH; Shinn, P; Stanton, BZ; Thomas, CJ; Vitanza, NA; Warren, KE; Wilson, KM; Woo, PJ; Zhang, X	1
Mason, WP; Richardson, PG; Roth, P; Weller, M	1
Boccellato, C; Fullstone, G; Idbaih, A; Juric, V; Kolbe, E; Lamfers, MLM; Murphy, BM; Peters, N; Rehm, M; Verreault, M	1
Alon, L; Bar-Shir, A; Bulte, JWM; Gilad, AA; Kato, Y; Korrer, MJ; Lim, HS; Pathak, AP; Yadav, NN	1
Dalhaug, A; Nieder, C; Norum, J; Pawinski, A; Syed, MA	1
Agati, R; Bartolini, S; Brandes, AA; Di Battista, M; Franceschi, E; Genestreti, G; Lamberti, G; Minichillo, S; Mura, A; Paccapelo, A	1
Bai, Y; Liu, M; Shen, D; Tao, S; Wang, T; Zhang, W	1
Luo, Q; Qian, Y; Qiao, S; Xu, G; Zhang, Z	1
Chen, S; Cheng, H; Dai, X; Liu, L; Shen, H; Zhang, P	1
Baeza-Kallee, N; Cappaï, J; Chocry, M; Colin, C; Figarella-Branger, D; Kovacic, H; Lafitte, D; Nuccio, C; Quillien, V; Raujol, J; Rougon, G; Soubéran, A; Tchoghandjian, A	1
Albert, FK; Baumgarten, P; Brokinkel, B; Ebel, H; Harter, PN; Hasselblatt, M; Mittelbronn, M; Plate, KH; Stummer, W; Zachskorn, C; Zinke, J	1
Auf, G; Bayerl, SH; Broggini, T; Bruenner, J; Czabanka, M; Harms, C; Harms, U; Heppner, FL; Jabouille, A; Koch, A; Kremenetskaia, I; Mueller, S; Nieminen, M; Parmaksiz, G; Topalovic, M; Vajkoczy, P	1
Al-Harbi, H; Choueiri, TK; Heng, DY; Knox, JJ; Kollmannsberger, C; MacKenzie, M; North, S; Rini, BI; Vickers, MM	1
Lei, C; Shuyun, H; Xiangrong, C; Yiquan, K; Yongjun, Y; Zhilin, Y	1
Chovanec, M; Mardiak, J; Mego, M; Obertova, J; Palacka, P; Rajec, J	1
Booth, L; Cruickshanks, N; Dent, P; Grant, S; Hamed, HA; Poklepovic, A; Sajithlal, GB; Syed, J; Tavallai, S	1
Fujita, T; Iwamoto, Y; Koike, H; Takeuchi, H; Tsujino, H	1
Amela, E; Blanc, E; Chevreau, C; Delva, R; Escudier, B; Ferlay, C; Négrier, S; Oudard, S; Ravaud, A; Rolland, F; Tosi, D	1
Buchroithner, J; Capper, D; Embacher, S; Gotwald, T; Haybaeck, J; Herrlinger, U; Holzner, B; Hutterer, M; Marosi, C; Moik, M; Nowosielski, M; Oberndorfer, S; Preusser, M; Seiz, M; Stockhammer, F; Stockhammer, G; Tuettenberg, J; Vajkoczy, P; Wick, A	1
Agarwal, N; Bjarnason, GA; Choueiri, TK; Donskov, F; Heng, DY; Knox, JJ; Kollmannsberger, C; Lee, J; Mackenzie, M; North, S; Pal, SK; Rha, SY; Rini, BI; Srinivas, S; Tan, MH; Vaishampayan, UN; Wood, LA; Yuasa, T	1
Fujimoto, K; Momose, H; Morizawa, Y; Oyama, N; Takada, S; Toyoshima, Y	1
Balaña, C; Capellades, J; Gallego, O; Gil, MJ; Gonzalez, S; Perez, P; Reynes, G; Ribalta, T; Verger, E	1
Czabanka, M; Parmaksız, G; Vajkoczy, P; Vinci, M	1
Ahn, H; Cho, YM; Hong, JH; Jeong, IG; Kim, CS; Lee, JL; Song, C; Song, SH; You, D	1
Burrell, K; Chung, C; Foltz, W; Hill, R; Jalali, S; Singh, S; Zadeh, G	1
Anastasiou, I; Bamia, C; Bamias, A; Beuselinck, B; Chrisofos, M; Constantinides, C; Deliveliotis, C; Dimopoulos, MA; Elaidi, TR; Escudier, B; Liontos, M; Mitropoulos, D; Oudard, S; Papatsoris, A; Stravodimos, K; Tzannis, K	1
Bao, X; Wang, MW; Zhang, YJ; Zhang, YP	1
Andrews, DW; Axelrod, R; Camphausen, K; Curran, WJ; Dicker, AP; Evans, J; Glass, J; Haacke, EM; Hillman, GG; Lin, A; Shi, W; Werner-Wasik, M; Wuthrick, EJ	1
Coquerel, B; Demange, E; Kassim, Y; Le Cerf, D; Perrot, V; Petit, A; Simon, T; Vannier, JP	1
Corbacioglu, S; Debatin, KM; Engelke, J; Fulda, S; Halatsch, ME; Karpel-Massler, G; Nonnenmacher, L; Simmet, T; Westhoff, MA	1
Dervan, PB; Raskatov, JA; Szablowski, JO	1
Dewhurst, S; Feng, C; Gelbard, HA; Granger, M; Polesskaya, O; Rhoo, KH; Sur, J	1
Bogdahn, U; Bosserhoff, AK; Brawanski, A; Hau, P; Heudorfer, F; Leukel, P; Meyer, K; Moeckel, S; Proescholdt, M; Riemenschneider, MJ; Seliger, C; Spang, R; Stangl, C; Vollmann-Zwerenz, A	1
Elledge, R; Foreman, C; Hilsenbeck, SG; Niravath, P; Rimawi, M; Rodriguez, A; Tham, YL; Wang, T	1
Buchfelder, M; Eyüpoglu, IY; Fan, Z; Ghoochani, A; Hatipoglu, G; Hock, SW; Savaskan, NE; Sehm, T; Weiss, R	1
Cheng, SY; Feng, H; Gao, WQ; Hou, Y; Hu, B; James, CD; Li, Y; Li, Z; Parsa, AT; Raizer, JJ; Sarkaria, JN; Xie, B; Yin, Y; Zhang, L; Zhang, W	1
Fujisawa, M; Furukawa, J; Kusuda, Y; Miyake, H; Muramaki, M; Terakawa, T	1
Finke, JH; Grabowski, M; Hambardzumyan, D; Huang, P; Raychaudhuri, B; Rayman, P; Vogelbaum, MA	1
Cardoso, AL; Costa, PM; Cunha, P; Custódia, C; Pedroso de Lima, MC; Pereira de Almeida, L	1
Allbritton, O; Angeles, AR; Basso, AD; Dai, C; Gray, K; Liang, L; Liu, M; Mansoor, UF; Siddiqui, MA; Tang, H; Vitharana, D; Yang, L	1
Bos, MM; De Santis, M; Eichelberg, C; Fischer von Weikersthal, L; Flörcken, A; Freier, W; Goebell, PJ; Gottstein, D; Hauswald, K; Indorf, M; Lerchenmüller, C; Los, M; Michel, MS; Pahernik, S; Schenck, M; Schirrmacher-Memmel, S; Staehler, M; van Arkel, C; Vervenne, WL; Zimmermann, U	1
Thoma, C	1
Chen, LF; Chen, YC; Chiang, CF; Hsieh, WY; Lin, WL; Wu, SK	1
Albiges, L; Escudier, B	1
Chen, M; Hui, H; Jin, B; Ma, P; Pei, S; Shen, F; Wang, Z; Zhou, W; Zhou, X	1
Ahluwalia, MS; Angelov, L; Barnett, GH; Brewer, CJ; Chao, ST; Elson, P; Mikkelsen, T; Parsons, MW; Peereboom, DM; Rump, M; Schilero, C; Smolenski, KN; Suh, JH; Vogelbaum, MA; Wang, D; Weil, RJ	1
Blaes, J; Broggini, T; Czabanka, M; Harms, C; Harms, U; Mueller, S; Stange, L; Thomé, C; Vajkoczy, P; Weiler, M; Wick, W; Wüstner, M	1
Du Four, S; Duerinck, J; Everaert, H; Hau, P; Michotte, A; Neyns, B; Sander, W; Van Binst, AM	1
Butowski, N; Cloughesy, TF; Colman, H; De Groot, JF; Haidar, S; Hsu, HH; Huse, J; Ligon, KL; Marimuthu, A; Molinaro, AM; Nayak, L; Nolop, KB; Omuro, AM; Perry, A; Phillips, J; Prados, M; Wen, PY; West, BL	1
Bogdahn, U; Bosserhoff, AK; Brawanski, A; Hau, P; Moeckel, S; Proescholdt, M; Riemenschneider, MJ; Spang, R; Vollmann-Zwerenz, A	1
Fang, L; Jiang, K; Wang, D; Wang, J; Zhao, J; Zhu, L	1
Jiang, X; Qi, B; Wang, Z; Xia, H; Zhou, T	1
Burbidge, S; Colapietro, A; Delle Monache, S; Festuccia, C; Gravina, GL; Mancini, A; Marampon, F; Patient, L; Richardson, PJ; Sferra, R; Vitale, F	1
Ferrière, JM; Grenier, N; Kilkoski, F; Ravaud, A; Sire, M; Wallerand, H	1
Gallo, JM; Zhou, Q	2
de Barros e Silva, MJ; de Paiva, TF; Fanelli, MF; Gimenes, DL; Rinck, JA	1
Czabanka, M; Heppner, F; Ullrich, A; Vajkoczy, P; Vinci, M	1
Hill, KL; Lipson, AC; Sheehan, JM	1
Asemissen, AM; Keilholz, U; Knoedler, M; Miller, K; Schmittel, A; Steiner, U; Thiel, E; Zimmermann, K	1
Li, X; Liu, J; Qiang, W; Yang, Y; Yao, J; Zeng, H; Zhu, Y	1
Abdulkarim, B; Aghi, M; Chahal, M; Christensen, JG; Famulski, K; Graham, K; Jacques, A; Lesniak, D; Murray, D; Sabri, S; Xu, Y	1
Dalhaug, A; Nieder, C	1
Culine, S; Patard, JJ; Pouessel, D	1
Dalhaug, A; Haukland, E; Nieder, C	1
Choueiri, TK; Dal Cin, P; Kelly, PJ; Perez-Atayde, AR; Sher, DJ; Weiss, SE	1
Andersen, E; Gopalakrishnan, M; Grønlien, JH; Lee, CH; Malysz, J; Thorin-Hagene, K; Ween, H	1
Bjarnason, GA; Bracarda, S; Carteni, G; Gore, ME; Hariharan, S; Hawkins, R; Lee, SH; Nieto, A; Oudard, S; Porta, C; Szczylik, C; Yuan, J	1
Haseke, N; Karl, A; Muacevic, A; Nuhn, P; Siebels, M; Staehler, M; Stief, CG; Tüllmann, C; Wowra, B	1
Claes, A; Hamans, BC; Heerschap, A; Jeuken, JW; Leenders, WP; Navis, AC; Wesseling, P	1
Addeo, R; Caraglia, M	1
Hashimoto, H	1
Allen, P; Jonasch, E; Mahajan, A; Tannir, N; Verma, J	1
Abrey, L; Camps, C; Chao, RC; Grossi, F; Mazieres, J; Novello, S; Patyna, S; Scagliotti, G; Thall, A; Usari, T; Vernejoux, JM; Wang, Z	1
Andrews, DW; Axelrod, R; Camphausen, KA; Curran, WJ; Dicker, AP; Glass, J; Hyslop, T; Kamrava, M; Machtay, M; Werner-Wasik, M; Wuthrick, EJ	1
Coan, A; Desjardins, A; Friedman, HS; Gururangan, S; Herndon, JE; Peters, KB; Reardon, DA; Rich, JN; Sathornsumetee, S; Vredenburgh, JJ	1
Barré, L; Bernaudin, M; Delamare, J; Divoux, D; Marteau, L; Petit, E; Roussel, S; Sobrio, F; Toutain, J; Valable, S	1
Debus, J; Han, N; Huber, PE; Kleber, S; Lahn, M; Martin-Villalba, A; Peschke, P; Röhrich, M; Timke, C; Tuettenberg, J; Wirkner, U; Zhang, M	1
DE Grève, J; DE Witte, O; DU Four, S; Huylebrouck, M; LE Mercier, M; Lv, S; Michotte, A; Neyns, B; Quartier, E; Sadones, J; Salmon, I; Teugels, E	1
George, S; Hornick, JL; Jagannathan, JP; Ramaiya, NH; Shinagare, AB	1
Lim, ZD; Mahajan, A; Tannir, NM; Weinberg, J	1
Bruce, JN; Canoll, P; Christensen, JG; Crisman, C; D'Amico, R; Ebiana, V; Gil, O; Kennedy, BC; Lei, L; Rosenfeld, SS; Sisti, J	1
Barcellos-Hoff, MH; Hardee, ME; Lonning, SM; Marciscano, AE; Medina-Ramirez, CM; Narayana, A; Zagzag, D	1
Chamberlain, M; Chowdhary, S; Pan, E; Potthast, L; Smith, P; Yu, D; Yue, B	1
Burrell, K; Camphausen, K; Chung, C; Foltz, W; Graves, C; Jaffray, D; Jalali, S; Lindsay, P; Ménard, C; Milosevic, M; Wildgoose, P; Zadeh, G	1
Gallia, GL; Joshi, AD; Loilome, W; Riggins, GJ; Siu, IM; Tyler, B	1
Fine, HA; Iwamoto, FM; Kreisl, TN; Salgado, C; Shih, JH; Smith, P; Sul, J	1
Bruce, JN; Canoll, P; Cardoso, AL; Costa, PM; Nóbrega, C; Pedroso de Lima, MC; Pereira de Almeida, LF	1
Adenis, A; Alt, M; Caty, A; Fumagalli, I; Penel, N; Vanhuyse, M; Zini, L	1
Agarwal, S; Chi, M; Dudek, AZ; Elmquist, WF; Mittapalli, RK; Oberoi, R; Raza, A; Singhal, M	1
Fueller, T; Hummel, V; Rieckmann, P; Tonn, JC; Wagner, S	1
MCAFEE, J; RUBENFELD, S; WINKELMAN, J	1
Adams, C; Braybrooke, JP; Cattell, E; Deplanque, G; Frith, P; Harris, AL; Huson, SM; Madhusudan, S; Moore, N; Price, P; Scigalla, P; Taylor, M; Tsaloumas, MD	1
Capelle, HH; Erber, R; Farhadi, MR; Ullrich, A; Vajkoczy, P	1
Dominici, C; Mancini, C; Mancuso, M; McDowell, HP; Raschellà, G; Tanno, B; Vitali, R	1
Christensen, JG; de Boüard, S; Gauduchon, P; Guillamo, JS; Herlin, P; Lemoisson, E; Raymond, E	1
Billemont, B; Rixe, O; Thibault, F	1
Belcaceres, JL; Cojocarasu, O; Halimi, P; Medioni, J; Oudard, S	1
Culine, S; Pouessel, D	1
Boven, E; Droogendijk, H; Haanen, JG; Helgason, HH; Mallo, HA; van den Eertwegh, AJ; van der Veldt, AA	1
Lee, YS; Sayeed, MM; Wurster, RD	1
Blaivas, M; Kish, PE; McMahon, G; Muraszko, KM; Ross, BD; Ross, DA; Strawderman, M	1
Kuno, T; Sasaki, M; Takamoto, T; Tamaki, N	1

Reviews

2 review(s) available for pyrroles and Brain Neoplasms

Article	Year
Proteasome inhibition for the treatment of glioblastoma. Expert opinion on investigational drugs, 2020, Volume: 29, Issue:10 Topics: Animals; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Drug Development; Glioblastoma; Humans; Lactones; Proteasome Inhibitors; Pyrroles	2020
Treatment of brain metastases from renal cell carcinoma with sunitinib and radiotherapy: our experience and review of the literature. International journal of urology : official journal of the Japanese Urological Association, 2011, Volume: 18, Issue:4 Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Retrospective Studies; Sunitinib	2011

Article

Year

Proteasome inhibition for the treatment of glioblastoma.

Expert opinion on investigational drugs, 2020, Volume: 29, Issue:10

Topics: Animals; Antineoplastic Agents; Bortezomib; Brain Neoplasms; Drug Development; Glioblastoma; Humans; Lactones; Proteasome Inhibitors; Pyrroles

2020

Treatment of brain metastases from renal cell carcinoma with sunitinib and radiotherapy: our experience and review of the literature.

International journal of urology : official journal of the Japanese Urological Association, 2011, Volume: 18, Issue:4

Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Retrospective Studies; Sunitinib

2011

Trials

15 trial(s) available for pyrroles and Brain Neoplasms

Article	Year
Myelopreservation with the CDK4/6 inhibitor trilaciclib in patients with small-cell lung cancer receiving first-line chemotherapy: a phase Ib/randomized phase II trial. Annals of oncology : official journal of the European Society for Medical Oncology, 2019, 10-01, Volume: 30, Issue:10 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Carboplatin; Cisplatin; Cyclin-Dependent Kinase 4; Cyclin-Dependent Kinase 6; Double-Blind Method; Etoposide; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Myeloid Cells; Paclitaxel; Prognosis; Pyrimidines; Pyrroles; Small Cell Lung Carcinoma; Survival Rate; Tissue Distribution	2019
A phase II trial of sunitinib in patients with renal cell cancer and untreated brain metastases. Clinical genitourinary cancer, 2014, Volume: 12, Issue:1 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Brain; Brain Neoplasms; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Prospective Studies; Pyrroles; Sunitinib; Survival; Treatment Outcome	2014
A single-arm phase II Austrian/German multicenter trial on continuous daily sunitinib in primary glioblastoma at first recurrence (SURGE 01-07). Neuro-oncology, 2014, Volume: 16, Issue:1 Topics: Adult; Aged; Angiogenesis Inhibitors; Brain Neoplasms; Drug Administration Schedule; Female; Follow-Up Studies; Glioblastoma; Humans; Indoles; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Prospective Studies; Pyrroles; Sunitinib; Survival Rate	2014
Sunitinib administered prior to radiotherapy in patients with non-resectable glioblastoma: results of a phase II study. Targeted oncology, 2014, Volume: 9, Issue:4 Topics: Aged; Antineoplastic Agents; Biopsy; Brain Neoplasms; Disease Progression; Disease-Free Survival; Female; Glioblastoma; Humans; Indoles; Magnetic Resonance Imaging; Male; Middle Aged; Pyrroles; Radiotherapy; Sunitinib; Time Factors; Treatment Outcome	2014
A phase II trial of capecitabine concomitantly with whole-brain radiotherapy followed by capecitabine and sunitinib for brain metastases from breast cancer. The oncologist, 2015, Volume: 20, Issue:1 Topics: Brain Neoplasms; Breast Neoplasms; Capecitabine; Combined Modality Therapy; Deoxycytidine; Disease-Free Survival; Female; Fluorouracil; Humans; Indoles; Pyrroles; Sunitinib	2015
SWITCH: A Randomised, Sequential, Open-label Study to Evaluate the Efficacy and Safety of Sorafenib-sunitinib Versus Sunitinib-sorafenib in the Treatment of Metastatic Renal Cell Cancer. European urology, 2015, Volume: 68, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Lymph Nodes; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Proportional Hazards Models; Pyrroles; Sorafenib; Sunitinib	2015
Phase II trial of sunitinib as adjuvant therapy after stereotactic radiosurgery in patients with 1-3 newly diagnosed brain metastases. Journal of neuro-oncology, 2015, Volume: 124, Issue:3 Topics: Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Cognition Disorders; Combined Modality Therapy; Dose-Response Relationship, Radiation; Female; Humans; Indoles; Magnetic Resonance Imaging; Male; Middle Aged; Neoplasm Recurrence, Local; Neuropsychological Tests; Pyrroles; Radiosurgery; Salvage Therapy; Sunitinib; Treatment Outcome	2015
Sunitinib Malate plus Lomustine for Patients with Temozolomide-refractory Recurrent Anaplastic or Low-grade Glioma. Anticancer research, 2015, Volume: 35, Issue:10 Topics: Adult; Antineoplastic Agents, Alkylating; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Dacarbazine; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Glioma; Humans; Indoles; Lomustine; Male; Middle Aged; Neoplasm Grading; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Pyrroles; Sunitinib; Survival Rate; Temozolomide	2015
Orally administered colony stimulating factor 1 receptor inhibitor PLX3397 in recurrent glioblastoma: an Ivy Foundation Early Phase Clinical Trials Consortium phase II study. Neuro-oncology, 2016, Volume: 18, Issue:4 Topics: Administration, Oral; Aminopyridines; Biomarkers, Tumor; Blood-Brain Barrier; Brain Neoplasms; Cohort Studies; Female; Follow-Up Studies; Glioblastoma; Humans; Immunoenzyme Techniques; Male; Middle Aged; Neoplasm Recurrence, Local; Neoplasm Staging; Prognosis; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor; Tissue Distribution; Tumor Burden	2016
Phase II study of sunitinib in patients with non-small cell lung cancer and irradiated brain metastases. Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2011, Volume: 6, Issue:7 Topics: Adenocarcinoma; Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Chemoradiotherapy; Cranial Irradiation; Female; Follow-Up Studies; Humans; Indoles; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Pyrroles; Sunitinib; Survival Rate; Treatment Outcome	2011
A phase 1b trial of the combination of the antiangiogenic agent sunitinib and radiation therapy for patients with primary and metastatic central nervous system malignancies. Cancer, 2011, Dec-15, Volume: 117, Issue:24 Topics: Aged; Angiogenesis Inhibitors; Biomarkers, Tumor; Brain Neoplasms; Combined Modality Therapy; Female; Humans; Indoles; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Middle Aged; Pyrroles; Radiotherapy Dosage; Sunitinib; Survival Analysis; Vascular Endothelial Growth Factor A	2011
Phase I study of sunitinib and irinotecan for patients with recurrent malignant glioma. Journal of neuro-oncology, 2011, Volume: 105, Issue:3 Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Disease-Free Survival; Female; Glioma; Humans; Indoles; Irinotecan; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Pyrroles; Sunitinib; Young Adult	2011
A prospective phase II single-institution trial of sunitinib for recurrent malignant glioma. Journal of neuro-oncology, 2012, Volume: 110, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Brain Neoplasms; Disease-Free Survival; Female; Glioma; Humans; Indoles; Kaplan-Meier Estimate; Male; Middle Aged; Neoplasm Recurrence, Local; Pyrroles; Sunitinib	2012
Continuous daily sunitinib for recurrent glioblastoma. Journal of neuro-oncology, 2013, Volume: 111, Issue:1 Topics: Administration, Oral; Adult; Aged; Angiogenesis Inhibitors; Brain Neoplasms; Drug Administration Schedule; Female; Follow-Up Studies; Glioblastoma; Humans; Indoles; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Pyrroles; Quality of Life; Sunitinib; Survival Rate	2013
Antiangiogenic therapy for von Hippel-Lindau disease. JAMA, 2004, Feb-25, Volume: 291, Issue:8 Topics: Adult; Angiogenesis Inhibitors; Brain Neoplasms; Female; Hemangioblastoma; Humans; Indoles; Male; Middle Aged; Pyrroles; Retinal Neoplasms; Spinal Cord Neoplasms; Treatment Outcome; Vascular Endothelial Growth Factor A; von Hippel-Lindau Disease	2004

Other Studies

90 other study(ies) available for pyrroles and Brain Neoplasms

Article	Year
Tumor Drug Concentration and Phosphoproteomic Profiles After Two Weeks of Treatment With Sunitinib in Patients with Newly Diagnosed Glioblastoma. Clinical cancer research : an official journal of the American Association for Cancer Research, 2022, 04-14, Volume: 28, Issue:8 Topics: Brain Neoplasms; Cell Line, Tumor; Glioblastoma; Humans; Indoles; Proteomics; Pyrroles; Sunitinib	2022
Luminescent Pyrrole-Based Phosphaphenalene Gold Complexes: Versatile Anticancer Tools with Wide Applicability. Chemistry (Weinheim an der Bergstrasse, Germany), 2022, Jun-15, Volume: 28, Issue:34 Topics: Antineoplastic Agents; Brain Neoplasms; Glioblastoma; Gold; Humans; Luminescence; Pyrroles	2022
Structure-activity relationship studies and in vitro and in vivo anticancer activity of novel 3-aroyl-1,4-diarylpyrroles against solid tumors and hematological malignancies. European journal of medicinal chemistry, 2020, Jan-01, Volume: 185 Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Female; Glioblastoma; Hematologic Neoplasms; Humans; Injections, Intraperitoneal; Injections, Subcutaneous; Mice; Mice, Inbred BALB C; Molecular Structure; Optical Imaging; Pyrroles; Structure-Activity Relationship; Tumor Cells, Cultured	2020
Therapeutic strategies for diffuse midline glioma from high-throughput combination drug screening. Science translational medicine, 2019, 11-20, Volume: 11, Issue:519 Topics: Animals; Brain Neoplasms; Brain Stem Neoplasms; Cell Death; Cell Line, Tumor; Drug Evaluation, Preclinical; Drug Synergism; Female; Glioma; High-Throughput Screening Assays; Humans; Lactones; Male; Metabolomics; Mice; Panobinostat; Pyrroles; Reproducibility of Results; Sequence Analysis, RNA; Transcription, Genetic; Xenograft Model Antitumor Assays	2019
Marizomib sensitizes primary glioma cells to apoptosis induced by a latest-generation TRAIL receptor agonist. Cell death & disease, 2021, 06-24, Volume: 12, Issue:7 Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Brain Neoplasms; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Drug Resistance, Neoplasm; Glioma; Humans; Lactones; Myeloid Cell Leukemia Sequence 1 Protein; Proteasome Inhibitors; Pyrimidines; Pyrroles; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; Spheroids, Cellular; Thiophenes; Time Factors	2021
Quantification and tracking of genetically engineered dendritic cells for studying immunotherapy. Magnetic resonance in medicine, 2018, Volume: 79, Issue:2 Topics: Animals; Biomedical Research; Brain Neoplasms; Cell Tracking; Dendritic Cells; Deoxycytidine; Drosophila melanogaster; Flow Cytometry; Genes, Insect; Genes, Reporter; Genetic Engineering; HEK293 Cells; Humans; Immunotherapy; Magnetic Resonance Imaging; Neoplasms, Experimental; Phosphotransferases (Alcohol Group Acceptor); Pyrroles	2018
Eligibility for phase 3 clinical trials of systemic therapy in real-world patients with metastatic renal cell cancer managed in a rural region. Medical oncology (Northwood, London, England), 2017, Volume: 34, Issue:9 Topics: Aged; Anilides; Antibodies, Monoclonal; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Clinical Trials, Phase III as Topic; Female; Humans; Indazoles; Indoles; Kidney Neoplasms; Male; Middle Aged; Nivolumab; Pyridines; Pyrimidines; Pyrroles; Retrospective Studies; Rural Population; Sulfonamides; Sunitinib	2017
Third-line therapy in recurrent glioblastoma: is it another chance for bevacizumab? Journal of neuro-oncology, 2018, Volume: 139, Issue:2 Topics: Acetanilides; Adult; Aged; Antineoplastic Agents, Immunological; Bevacizumab; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; Female; Follow-Up Studies; Glioblastoma; Humans; Male; Middle Aged; Neoplasm Recurrence, Local; Pyrroles; Quinolines; Retreatment; Survival Analysis; Treatment Outcome; Tumor Suppressor Proteins; Young Adult	2018
TGF-β/Smads Signaling Affects Radiation Response and Prolongs Survival by Regulating DNA Repair Genes in Malignant Glioma. DNA and cell biology, 2018, Volume: 37, Issue:11 Topics: Acid Anhydride Hydrolases; Animals; ATP-Binding Cassette Transporters; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; DNA Damage; DNA Glycosylases; DNA Modification Methylases; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Gamma Rays; Gene Expression Regulation, Neoplastic; Glioma; Humans; Mice; MutL Protein Homolog 1; MutS Homolog 2 Protein; Neuroglia; Pyrazoles; Pyrroles; RNA, Small Interfering; Signal Transduction; Smad Proteins; Survival Analysis; Transforming Growth Factor beta; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays	2018
Long-term characterization of activated microglia/macrophages facilitating the development of experimental brain metastasis through intravital microscopic imaging. Journal of neuroinflammation, 2019, Jan-07, Volume: 16, Issue:1 Topics: Aminopyridines; Animals; Brain; Brain Neoplasms; Cell Line, Tumor; CX3C Chemokine Receptor 1; Disease Models, Animal; Functional Laterality; Gene Expression Regulation, Neoplastic; Green Fluorescent Proteins; Intravital Microscopy; Macrophages; Matrix Metalloproteinase 3; Melanoma; Mice; Mice, Inbred C57BL; Mice, Transgenic; Microglia; Pyrroles; Time Factors; Zonula Occludens-1 Protein	2019
Anti-glioma trichobamide A with an unprecedented tetrahydro-5H-furo[2,3-b]pyrrol-5-one functionality from ascidian-derived fungus Trichobotrys effuse 4729. Chemical communications (Cambridge, England), 2019, Jan-29, Volume: 55, Issue:10 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Crystallography, X-Ray; Down-Regulation; Fungi; Glioma; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Tumor Suppressor Protein p53; Up-Regulation; Urochordata	2019
Inhibitor of Apoptosis Proteins Determines Glioblastoma Stem-Like Cell Fate in an Oxygen-Dependent Manner. Stem cells (Dayton, Ohio), 2019, Volume: 37, Issue:6 Topics: Adaptor Proteins, Signal Transducing; Adrenomedullin; Apoptosis; Baculoviral IAP Repeat-Containing 3 Protein; Brain Neoplasms; Carbonic Anhydrase IX; Cell Differentiation; Cell Hypoxia; Cell Line, Tumor; Cell Proliferation; Cyclohexanes; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Inhibitor of Apoptosis Proteins; Neoplasm Proteins; Neoplastic Stem Cells; Oxygen; Pyrroles; Signal Transduction; Spheroids, Cellular; Tissue Culture Techniques; X-Linked Inhibitor of Apoptosis Protein	2019
Expression of vascular endothelial growth factor (VEGF) and its receptors VEGFR1 and VEGFR2 in primary and recurrent WHO grade III meningiomas. Histology and histopathology, 2013, Volume: 28, Issue:9 Topics: Aged; Aged, 80 and over; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Hypoxia; Immunohistochemistry; In Situ Hybridization; Indoles; Male; Meningioma; Middle Aged; Pyrroles; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2	2013
Combined temozolomide and sunitinib treatment leads to better tumour control but increased vascular resistance in O6-methylguanine methyltransferase-methylated gliomas. European journal of cancer (Oxford, England : 1990), 2013, Volume: 49, Issue:9 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Proliferation; Dacarbazine; DNA Methylation; DNA, Neoplasm; Glioma; Heterografts; Humans; Indoles; Male; Mice; Mice, Nude; O(6)-Methylguanine-DNA Methyltransferase; Pyrroles; Sunitinib; Temozolomide; Tumor Cells, Cultured; Vascular Resistance	2013
Prognostic factors of survival for patients with metastatic renal cell carcinoma with brain metastases treated with targeted therapy: results from the international metastatic renal cell carcinoma database consortium. Clinical genitourinary cancer, 2013, Volume: 11, Issue:3 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Bevacizumab; Brain Neoplasms; Carcinoma, Renal Cell; Databases, Factual; Humans; Indoles; Kidney Neoplasms; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Sirolimus; Sorafenib; Sunitinib; Survival; Treatment Outcome	2013
Atorvastatin suppresses glioma invasion and migration by reducing microglial MT1-MMP expression. Journal of neuroimmunology, 2013, Jul-15, Volume: 260, Issue:1-2 Topics: Atorvastatin; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Glioblastoma; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; MAP Kinase Signaling System; Matrix Metalloproteinase 14; Matrix Metalloproteinase 2; Microglia; Neoplasm Invasiveness; p38 Mitogen-Activated Protein Kinases; Pyrroles	2013
[Is the same tyrosine kinase inhibitor still effective after development of brain metastases? A Case report]. Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti, 2013, Volume: 26, Issue:4 Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Disease Progression; Enzyme Inhibitors; Humans; Indoles; Kidney Neoplasms; Male; Protein-Tyrosine Kinases; Pyrroles; Sirolimus; Sunitinib; TOR Serine-Threonine Kinases; Treatment Outcome	2013
Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ERBB2 therapy. Cancer biology & therapy, 2013, Oct-01, Volume: 14, Issue:10 Topics: Animals; Anoikis; Antineoplastic Agents, Hormonal; Apoptosis Regulatory Proteins; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; bcl-X Protein; Brain Neoplasms; Breast Neoplasms; Cell Survival; Drug Resistance, Neoplasm; Epigenesis, Genetic; ErbB Receptors; Female; Gene Expression; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Histone Deacetylase Inhibitors; Humans; Indoles; Lapatinib; Mice; Mice, Nude; Myeloid Cell Leukemia Sequence 1 Protein; Neoplastic Stem Cells; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Quinazolines; Receptor, ErbB-2; RNA, Small Interfering; Valproic Acid; Xenograft Model Antitumor Assays	2013
Sunitinib treatment for multiple brain metastases from jejunal gastrointestinal stromal tumor: case report. Neurologia medico-chirurgica, 2014, Volume: 54, Issue:8 Topics: Aged; Angiogenesis Inhibitors; Brain Neoplasms; Chemotherapy, Adjuvant; Combined Modality Therapy; Gastrointestinal Stromal Tumors; Humans; Indoles; Jejunal Neoplasms; Magnetic Resonance Imaging; Male; Pyrroles; Radiosurgery; Sunitinib; Tomography, X-Ray Computed	2014
Outcomes of patients with metastatic renal cell carcinoma that do not meet eligibility criteria for clinical trials. Annals of oncology : official journal of the European Society for Medical Oncology, 2014, Volume: 25, Issue:1 Topics: Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain Neoplasms; Carcinoma, Renal Cell; Clinical Trials as Topic; Disease-Free Survival; Eligibility Determination; Humans; Indazoles; Indoles; Kaplan-Meier Estimate; Karnofsky Performance Status; Kidney Neoplasms; Middle Aged; Molecular Targeted Therapy; Niacinamide; Phenylurea Compounds; Pyrimidines; Pyrroles; Sorafenib; Sulfonamides; Sunitinib; Treatment Outcome	2014
[Brain metastasis which appeared during complete response of lung metastatic lesion by sunitinib treatment in a patient with renal cell carcinoma]. Hinyokika kiyo. Acta urologica Japonica, 2013, Volume: 59, Issue:12 Topics: Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Male; Middle Aged; Pyrroles; Remission Induction; Sunitinib	2013
Antiangiogenic therapy inhibits the recruitment of vascular accessory cells to the perivascular niche in glioma angiogenesis. Journal of vascular research, 2014, Volume: 51, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Biomarkers, Tumor; Bone Marrow Cells; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Glioma; Indoles; Mice; Mice, Nude; Neovascularization, Pathologic; Pyrroles; Rats; Sunitinib; Tumor Microenvironment	2014
Predictive role of tissue-based molecular markers in patients treated with sunitinib for metastatic renal cell carcinoma. World journal of urology, 2015, Volume: 33, Issue:1 Topics: Adult; Aged; Antineoplastic Agents; Biomarkers; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Cohort Studies; Female; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Nephrectomy; Predictive Value of Tests; Proto-Oncogene Proteins c-sis; Pyrroles; Receptor, Platelet-Derived Growth Factor beta; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2015
MRI biomarkers identify the differential response of glioblastoma multiforme to anti-angiogenic therapy. Neuro-oncology, 2014, Volume: 16, Issue:6 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal, Humanized; Bevacizumab; Biomarkers; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Glioblastoma; Humans; Image Processing, Computer-Assisted; Indoles; Magnetic Resonance Imaging; Mice; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Recombinant Fusion Proteins; Sunitinib	2014
Prognostic significance of cytoreductive nephrectomy in patients with synchronous metastases from renal cell carcinoma treated with first-line sunitinib: a European multiinstitutional study. Clinical genitourinary cancer, 2014, Volume: 12, Issue:5 Topics: Aged; Antineoplastic Agents; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Cytoreduction Surgical Procedures; Disease-Free Survival; Europe; Female; Humans; Indoles; Kidney Neoplasms; Male; Neoplasm Metastasis; Nephrectomy; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sunitinib; Treatment Outcome; Vascular Endothelial Growth Factor A	2014
Early monitoring antiangiogenesis treatment response of Sunitinib in U87MG Tumor Xenograft by (18)F-FLT MicroPET/CT imaging. BioMed research international, 2014, Volume: 2014 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Dideoxynucleosides; Drug Monitoring; Early Detection of Cancer; Female; Glioblastoma; Indoles; Mice; Mice, Inbred C57BL; Mice, Nude; Multimodal Imaging; Positron-Emission Tomography; Pyrroles; Radiopharmaceuticals; Sunitinib; Tomography, X-Ray Computed; Treatment Outcome	2014
A pilot study of hypofractionated stereotactic radiation therapy and sunitinib in previously irradiated patients with recurrent high-grade glioma. International journal of radiation oncology, biology, physics, 2014, Oct-01, Volume: 90, Issue:2 Topics: Adult; Aged; Angiogenesis Inhibitors; Antineoplastic Agents; Brain Neoplasms; Combined Modality Therapy; Disease-Free Survival; Dose Fractionation, Radiation; Drug Administration Schedule; Female; Glioma; Humans; Indoles; Male; Middle Aged; Neoplasm Recurrence, Local; Pilot Projects; Pyrroles; Radiosurgery; Remission Induction; Retreatment; Sunitinib	2014
Direct effect of bevacizumab on glioblastoma cell lines in vitro. Neuromolecular medicine, 2014, Volume: 16, Issue:4 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Autocrine Communication; Bevacizumab; Brain Neoplasms; Calcium Signaling; Cell Culture Techniques; Cell Division; Cell Line, Tumor; Cell Movement; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Hyaluronic Acid; Hydrogels; Indoles; MAP Kinase Signaling System; Neoplasm Invasiveness; Neoplasm Proteins; Placenta Growth Factor; Pregnancy Proteins; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrroles; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-1; Vascular Endothelial Growth Factor Receptor-2	2014
RIST: a potent new combination therapy for glioblastoma. International journal of cancer, 2015, Feb-15, Volume: 136, Issue:4 Topics: Adolescent; Animals; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Camptothecin; Cell Line, Tumor; Child; Dacarbazine; Female; Glioblastoma; Humans; Indoles; Irinotecan; Male; Membrane Potential, Mitochondrial; Mice, Inbred NOD; Molecular Targeted Therapy; Pyrroles; Sirolimus; Sunitinib; Temozolomide; Xenograft Model Antitumor Assays	2015
Tumor xenograft uptake of a pyrrole-imidazole (Py-Im) polyamide varies as a function of cell line grafted. Journal of medicinal chemistry, 2014, Oct-23, Volume: 57, Issue:20 Topics: Animals; Brain Neoplasms; Cell Line, Tumor; Collagen; Drug Combinations; Humans; Imidazoles; Laminin; Lung Neoplasms; Male; Mice, Inbred BALB C; Nylons; Prostatic Neoplasms; Proteoglycans; Pyrroles; Tissue Distribution; Xenograft Model Antitumor Assays	2014
Pharmacologic inhibition of MLK3 kinase activity blocks the in vitro migratory capacity of breast cancer cells but has no effect on breast cancer brain metastasis in a mouse xenograft model. PloS one, 2014, Volume: 9, Issue:9 Topics: Animals; Brain Neoplasms; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Disease Models, Animal; Female; MAP Kinase Kinase Kinases; Mice; Mice, Nude; Mitogen-Activated Protein Kinase Kinase Kinase 11; Neoplasm Transplantation; Protein Kinase Inhibitors; Pyridines; Pyrroles; Transplantation, Heterologous	2014
Response-predictive gene expression profiling of glioma progenitor cells in vitro. PloS one, 2014, Volume: 9, Issue:9 Topics: Antineoplastic Agents; Apoptosis; Biomarkers, Pharmacological; Brain Neoplasms; Cell Differentiation; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Humans; Indoles; Microarray Analysis; Neoplasm Proteins; Neoplastic Stem Cells; Pyrroles; Signal Transduction; Sunitinib; Tumor Cells, Cultured	2014
Sunitinib impedes brain tumor progression and reduces tumor-induced neurodegeneration in the microenvironment. Cancer science, 2015, Volume: 106, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Astrocytes; Brain Neoplasms; Cell Death; Cell Line, Tumor; Cell Proliferation; Disease Progression; Endothelial Cells; Glioma; Humans; Indoles; Mice; Neovascularization, Pathologic; Neurodegenerative Diseases; Neurons; Neuroprotective Agents; Pyrroles; Rats; Rodentia; Sunitinib; Tumor Microenvironment; Vascular Endothelial Growth Factor Receptor-2	2015
Protein kinase A-dependent phosphorylation of Dock180 at serine residue 1250 is important for glioma growth and invasion stimulated by platelet derived-growth factor receptor α. Neuro-oncology, 2015, Volume: 17, Issue:6 Topics: Animals; Brain Neoplasms; Carbazoles; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Survival; Cyclic AMP-Dependent Protein Kinases; Female; Glioblastoma; HEK293 Cells; Humans; Isoquinolines; Mice; Phosphorylation; Platelet-Derived Growth Factor; Protein Kinase Inhibitors; Pyrroles; rac GTP-Binding Proteins; Receptor, Platelet-Derived Growth Factor alpha; Signal Transduction; Sulfonamides	2015
Myeloid derived suppressor cell infiltration of murine and human gliomas is associated with reduction of tumor infiltrating lymphocytes. Journal of neuro-oncology, 2015, Volume: 122, Issue:2 Topics: Animals; Antineoplastic Agents; Bone Marrow; Brain; Brain Neoplasms; Cell Line; Chickens; Glioma; Humans; Indoles; Lymphocytes, Tumor-Infiltrating; Mice, Transgenic; Myeloid Cells; Neoplasm Transplantation; Protein-Tyrosine Kinases; Pyrroles; Spleen; Sunitinib; Survival Analysis; T-Lymphocytes; Treatment Outcome	2015
MiRNA-21 silencing mediated by tumor-targeted nanoparticles combined with sunitinib: A new multimodal gene therapy approach for glioblastoma. Journal of controlled release : official journal of the Controlled Release Society, 2015, Jun-10, Volume: 207 Topics: Angiogenesis Inhibitors; Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Chemistry, Pharmaceutical; Chemotherapy, Adjuvant; Drug Carriers; Gene Expression Regulation, Neoplastic; Glioblastoma; Indoles; Male; Mice, Inbred C57BL; MicroRNAs; Nanomedicine; Nanoparticles; Oligonucleotides, Antisense; Protein Kinase Inhibitors; Pyrroles; rhoB GTP-Binding Protein; RNAi Therapeutics; Scorpion Venoms; Sunitinib; Technology, Pharmaceutical; Time Factors; Tumor Burden	2015
Discovery of novel spiro 1,3,4-thiadiazolines as potent, orally bioavailable and brain penetrant KSP inhibitors. Bioorganic & medicinal chemistry, 2015, May-15, Volume: 23, Issue:10 Topics: Administration, Oral; Animals; Antineoplastic Agents; Biomarkers; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Dogs; Drug Discovery; HCT116 Cells; Histones; Humans; Kinesins; Male; Mice; Permeability; Piperidines; Pyrimidines; Pyrroles; Rats; Spiro Compounds; Thiadiazoles; Thiones; Tubulin Modulators; Xenograft Model Antitumor Assays	2015
Kidney cancer: SWITCHing inconsequential. Nature reviews. Urology, 2015, Volume: 12, Issue:6 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Niacinamide; Phenylurea Compounds; Pyrroles	2015
Targeting microbubbles-carrying TGFβ1 inhibitor combined with ultrasound sonication induce BBB/BTB disruption to enhance nanomedicine treatment for brain tumors. Journal of controlled release : official journal of the Controlled Release Society, 2015, Aug-10, Volume: 211 Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Capillary Permeability; Drug Delivery Systems; Male; Mice; Mice, Inbred ICR; Mice, SCID; Microbubbles; Nanomedicine; Pyrazoles; Pyrroles; Rats; Rats, Sprague-Dawley; Sonication; Transforming Growth Factor beta1	2015
Sorafenib-Sunitinib Sequence: The Jury Is Out. European urology, 2015, Volume: 68, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Niacinamide; Phenylurea Compounds; Pyrroles; Sorafenib; Sunitinib	2015
GSK1838705A, an IGF-1R inhibitor, inhibits glioma cell proliferation and suppresses tumor growth in vivo. Molecular medicine reports, 2015, Volume: 12, Issue:4 Topics: Animals; Antineoplastic Agents; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Movement; Cell Proliferation; Dose-Response Relationship, Drug; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Mice; Mice, Nude; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Signal Transduction; Xenograft Model Antitumor Assays	2015
NDRG1 overexpressing gliomas are characterized by reduced tumor vascularization and resistance to antiangiogenic treatment. Cancer letters, 2016, 10-01, Volume: 380, Issue:2 Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Cell Cycle Proteins; Cell Line, Tumor; Culture Media, Conditioned; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Glioma; Human Umbilical Vein Endothelial Cells; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Mice; Mutation; Neovascularization, Pathologic; Neovascularization, Physiologic; NF-kappa B; Promoter Regions, Genetic; Pyrroles; RNA Interference; Signal Transduction; Sunitinib; Time Factors; Transcription Factor AP-1; Transfection; Tumor Burden; Tumor Necrosis Factor Ligand Superfamily Member 15; Up-Regulation	2016
Validation Study: Response-Predictive Gene Expression Profiling of Glioma Progenitor Cells In Vitro. PloS one, 2016, Volume: 11, Issue:3 Topics: Brain Neoplasms; Cell Proliferation; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Humans; Indoles; Microarray Analysis; Neoplastic Stem Cells; Pyrroles; Sunitinib	2016
Jumonji AT-rich interactive domain 1B overexpression is associated with the development and progression of glioma. International journal of molecular medicine, 2016, Volume: 38, Issue:1 Topics: Animals; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Down-Regulation; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Immunohistochemistry; Jumonji Domain-Containing Histone Demethylases; Mice, Inbred BALB C; Mice, Nude; Neoplasm Invasiveness; Nuclear Proteins; Phosphorylation; Pyrazoles; Pyrroles; Repressor Proteins; RNA, Messenger; Smad2 Protein; Spheroids, Cellular	2016
HSP47 Promotes Glioblastoma Stemlike Cell Survival by Modulating Tumor Microenvironment Extracellular Matrix through TGF-β Pathway. ACS chemical neuroscience, 2017, 01-18, Volume: 8, Issue:1 Topics: Analysis of Variance; Animals; Brain Neoplasms; Cell Survival; Computational Biology; Disease Models, Animal; Extracellular Matrix; Flow Cytometry; Gene Expression Regulation, Neoplastic; Glioblastoma; HSP47 Heat-Shock Proteins; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplastic Stem Cells; Platelet Endothelial Cell Adhesion Molecule-1; Pyrazoles; Pyrroles; RNA, Messenger; Transforming Growth Factor beta; Tumor Cells, Cultured; Tumor Microenvironment; Xenograft Model Antitumor Assays	2017
The brain-penetrating CXCR4 antagonist, PRX177561, increases the antitumor effects of bevacizumab and sunitinib in preclinical models of human glioblastoma. Journal of hematology & oncology, 2017, 01-05, Volume: 10, Issue:1 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Brain; Brain Neoplasms; Cell Line, Tumor; Drug Evaluation, Preclinical; Drug Interactions; Drug Synergism; Glioblastoma; Heterografts; Humans; Indoles; Mice; Pyrroles; Receptors, CXCR4; Sunitinib	2017
[Anti-angiogenic treatment in the management of metastatic renal cell carcinoma]. Bulletin du cancer, 2008, Volume: 95, Issue:9 Topics: Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Brain Neoplasms; Carcinoma, Renal Cell; Drug Administration Schedule; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Pyridines; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib	2008
Differential effect of sunitinib on the distribution of temozolomide in an orthotopic glioma model. Neuro-oncology, 2009, Volume: 11, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Brain Neoplasms; Dacarbazine; Drug Interactions; Glioma; Humans; Immunohistochemistry; In Situ Nick-End Labeling; Indoles; Male; Mice; Mice, Nude; Pyrroles; Sunitinib; Temozolomide; Tissue Distribution; Xenograft Model Antitumor Assays	2009
Tuberculosis in a patient on temozolomide: a case report. Journal of neuro-oncology, 2009, Volume: 92, Issue:1 Topics: Anti-Infective Agents; Anti-Inflammatory Agents; Anti-Ulcer Agents; Antibiotics, Antitubercular; Anticholesteremic Agents; Anticonvulsants; Antineoplastic Agents, Alkylating; Atorvastatin; Brain Neoplasms; Combined Modality Therapy; Cyclosporine; Dacarbazine; Dexamethasone; Female; Fluoxetine; Glioblastoma; Heptanoic Acids; Humans; Immunosuppressive Agents; Isoniazid; Middle Aged; Omeprazole; Phenobarbital; Prednisone; Pyrazinamide; Pyrroles; Radiotherapy; Red-Cell Aplasia, Pure; Rifampin; Temozolomide; Trimethoprim, Sulfamethoxazole Drug Combination; Tuberculosis, Pulmonary	2009
Effects of sunitinib on tumor hemodynamics and delivery of chemotherapy. International journal of cancer, 2009, Mar-15, Volume: 124, Issue:6 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Division; Cell Line, Tumor; Desmin; Doxorubicin; Glioblastoma; Hemodynamics; Indoles; Mice; Mice, Nude; Microcirculation; Pyrroles; Sunitinib	2009
Brain magnetic resonance imaging changes after sorafenib and sunitinib chemotherapy in patients with advanced renal cell and breast carcinoma. Journal of neurosurgery, 2009, Volume: 111, Issue:3 Topics: Aged; Antineoplastic Agents; Benzenesulfonates; Brain; Brain Edema; Brain Neoplasms; Breast Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Magnetic Resonance Imaging; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Prospective Studies; Pyridines; Pyrroles; Seizures; Sorafenib; Sunitinib	2009
Sunitinib treatment for patients with advanced clear-cell renal-cell carcinoma after progression on sorafenib. Oncology, 2009, Volume: 76, Issue:5 Topics: Adult; Aged; Antineoplastic Agents; Benzenesulfonates; Bone Neoplasms; Brain Neoplasms; Carcinoma, Renal Cell; Disease Progression; Female; Humans; Indoles; Kidney Neoplasms; Liver Neoplasms; Lung Neoplasms; Male; Middle Aged; Neoplasm Staging; Niacinamide; Phenylurea Compounds; Prognosis; Prospective Studies; Pyridines; Pyrroles; Salvage Therapy; Sorafenib; Sunitinib; Survival Rate; Treatment Outcome	2009
Quantification of sunitinib in mouse plasma, brain tumor and normal brain using liquid chromatography-electrospray ionization-tandem mass spectrometry and pharmacokinetic application. Journal of pharmaceutical and biomedical analysis, 2010, Mar-11, Volume: 51, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Brain; Brain Neoplasms; Chromatography, Liquid; Drug Stability; Glioma; Humans; Indoles; Infusions, Intravenous; Male; Mice; Mice, Nude; Pyrroles; Reproducibility of Results; Spectrometry, Mass, Electrospray Ionization; Sunitinib; Tandem Mass Spectrometry; Tissue Distribution	2010
Multifocal brain metastases in clear cell renal cell carcinoma with complete response to sunitinib. Urologia internationalis, 2009, Volume: 83, Issue:4 Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Male; Pyrroles; Remission Induction; Sunitinib	2009
MGMT modulates glioblastoma angiogenesis and response to the tyrosine kinase inhibitor sunitinib. Neuro-oncology, 2010, Volume: 12, Issue:8 Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Blotting, Western; Brain Neoplasms; Cell Line, Tumor; Cell Separation; Combined Modality Therapy; Dacarbazine; DNA Modification Methylases; DNA Repair Enzymes; Drug Resistance, Neoplasm; Enzyme-Linked Immunosorbent Assay; Flow Cytometry; Gene Expression; Gene Expression Profiling; Glioblastoma; Humans; Indoles; Mice; Mice, Nude; Neovascularization, Pathologic; Protein Kinase Inhibitors; Pyrroles; Radiotherapy; Reverse Transcriptase Polymerase Chain Reaction; Sunitinib; Temozolomide; Tumor Suppressor Proteins; Xenograft Model Antitumor Assays	2010
A new prognostic score derived from phase I study participants with advanced solid tumours is also valid in patients with brain metastasis. Anticancer research, 2010, Volume: 30, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Brain Neoplasms; Clinical Trials, Phase I as Topic; Combined Modality Therapy; Databases, Factual; Erlotinib Hydrochloride; Humans; Indoles; Middle Aged; Neoplasms; Prognosis; Pyrroles; Quinazolines; Severity of Illness Index; Sunitinib; Trastuzumab	2010
[Advanced renal carcinomas with special situations. How to treat them?]. Bulletin du cancer, 2010, Volume: 97 Topics: Aged; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Brain Neoplasms; Carcinoma, Renal Cell; Everolimus; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Kidney Neoplasms; Niacinamide; Phenylurea Compounds; Protein Serine-Threonine Kinases; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sirolimus; Sorafenib; Sunitinib; TOR Serine-Threonine Kinases; Vascular Endothelial Growth Factor A	2010
Leptomeningeal carcinomatosis from renal cell cancer: treatment attempt with radiation and sunitinib (case report). World journal of surgical oncology, 2010, May-05, Volume: 8 Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Combined Modality Therapy; Fatal Outcome; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Magnetic Resonance Imaging; Male; Meningeal Carcinomatosis; Pyrroles; Radiotherapy Dosage; Sunitinib; Tomography, X-Ray Computed	2010
Sunitinib-induced pseudoprogression after whole-brain radiotherapy for metastatic renal cell carcinoma. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2010, Sep-01, Volume: 28, Issue:25 Topics: Adolescent; Adult; Brain Neoplasms; Carcinoma, Renal Cell; Combined Modality Therapy; Female; Humans; Indoles; Neoplasm Metastasis; Pyrroles; Sunitinib	2010
Alpha3* and alpha 7 nAChR-mediated Ca2+ transient generation in IMR-32 neuroblastoma cells. Neurochemistry international, 2010, Volume: 57, Issue:3 Topics: alpha7 Nicotinic Acetylcholine Receptor; Benzamides; Brain Neoplasms; Bridged Bicyclo Compounds; Calcium Channel Blockers; Calcium Signaling; Calcium-Transporting ATPases; Cell Line, Tumor; Data Interpretation, Statistical; Diltiazem; Electrophysiology; Endoplasmic Reticulum; Humans; Neuroblastoma; Nicotinic Agonists; Nitrendipine; Patch-Clamp Techniques; Pyrroles; Receptors, Nicotinic; Sulfonamides	2010
Sunitinib in metastatic renal cell carcinoma patients with brain metastases. Cancer, 2011, Feb-01, Volume: 117, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Disease-Free Survival; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Sunitinib	2011
Simultaneous anti-angiogenic therapy and single-fraction radiosurgery in clinically relevant metastases from renal cell carcinoma. BJU international, 2011, Volume: 108, Issue:5 Topics: Adult; Aged; Aged, 80 and over; Angiogenesis Inhibitors; Brain Neoplasms; Carcinoma, Renal Cell; Chemotherapy, Adjuvant; Female; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Pyrroles; Radiosurgery; Spinal Neoplasms; Sunitinib; Survival Analysis; Treatment Outcome; Young Adult	2011
Effects of targeting the VEGF and PDGF pathways in diffuse orthotopic glioma models. The Journal of pathology, 2011, Volume: 223, Issue:5 Topics: Angiogenesis Inhibitors; Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Blood-Brain Barrier; Brain Neoplasms; Glioma; Humans; Indoles; Magnetic Resonance Imaging; Mice; Mice, Nude; Neovascularization, Pathologic; Piperidines; Pyrroles; Quinazolines; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Sunitinib; Vascular Endothelial Growth Factor A; Xenograft Model Antitumor Assays	2011
The oral tyrosine kinase inhibitors lapatinib and sunitinib: new opportunities for the treatment of brain metastases from breast cancer? Expert review of anticancer therapy, 2011, Volume: 11, Issue:2 Topics: Antineoplastic Agents; Brain Neoplasms; Breast Neoplasms; Female; Humans; Indoles; Lapatinib; Protein Kinase Inhibitors; Pyrroles; Quinazolines; Sunitinib	2011
Editorial comment to "Treatment of brain metastases from renal cell carcinoma with sunitinib and radiotherapy: our experience and review of the literature". International journal of urology : official journal of the Japanese Urological Association, 2011, Volume: 18, Issue:4 Topics: Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Pyrroles	2011
Impact of tyrosine kinase inhibitors on the incidence of brain metastasis in metastatic renal cell carcinoma. Cancer, 2011, Nov-01, Volume: 117, Issue:21 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzenesulfonates; Brain Neoplasms; Carcinoma, Renal Cell; Female; Humans; Incidence; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Protein-Tyrosine Kinases; Pyridines; Pyrroles; Sorafenib; Sunitinib	2011
Complementary information from magnetic resonance imaging and (18)F-fluoromisonidazole positron emission tomography in the assessment of the response to an antiangiogenic treatment in a rat brain tumor model. Nuclear medicine and biology, 2011, Volume: 38, Issue:6 Topics: Angiogenesis Inhibitors; Animals; Biological Transport; Brain; Brain Neoplasms; Cell Hypoxia; Cell Line, Tumor; Cerebrovascular Circulation; Disease Models, Animal; Glioma; Indoles; Kinetics; Magnetic Resonance Imaging; Misonidazole; Neovascularization, Pathologic; Permeability; Positron-Emission Tomography; Pyrroles; Rats; Sunitinib; Treatment Outcome	2011
Blockade of TGF-β signaling by the TGFβR-I kinase inhibitor LY2109761 enhances radiation response and prolongs survival in glioblastoma. Cancer research, 2011, Dec-01, Volume: 71, Issue:23 Topics: Animals; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; DNA Damage; DNA Repair; Glioblastoma; Humans; Mesenchymal Stem Cells; Mice; Mice, Inbred BALB C; Mice, SCID; Microarray Analysis; Neoplasm Invasiveness; Neoplastic Stem Cells; Neovascularization, Pathologic; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Pyrazoles; Pyrroles; Radiation Tolerance; Radiation-Sensitizing Agents; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Transforming Growth Factor beta; Xenograft Model Antitumor Assays	2011
Correlation between IDH1 gene mutation status and survival of patients treated for recurrent glioma. Anticancer research, 2011, Volume: 31, Issue:12 Topics: Adult; Aged; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Bevacizumab; Brain Neoplasms; Cetuximab; ErbB Receptors; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; Humans; Indoles; Isocitrate Dehydrogenase; Male; Middle Aged; Mutation; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Recurrence; Sunitinib	2011
Intracranial metastasis from pediatric GI stromal tumor. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2012, Apr-01, Volume: 30, Issue:10 Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Benzenesulfonates; Brain Neoplasms; Drug Administration Schedule; Gastrointestinal Stromal Tumors; Humans; Imatinib Mesylate; Indoles; Liver Neoplasms; Male; Niacinamide; Phenylurea Compounds; Piperazines; Protein-Tyrosine Kinases; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Stomach Neoplasms; Sunitinib; Treatment Outcome	2012
Outcome of patients with renal cell carcinoma metastatic to the brain treated with sunitinib without local therapy. American journal of clinical oncology, 2013, Volume: 36, Issue:3 Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Follow-Up Studies; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Neoplasm Staging; Pyrroles; Retrospective Studies; Sunitinib; Survival Rate; Treatment Outcome	2013
The addition of Sunitinib to radiation delays tumor growth in a murine model of glioblastoma. Neurological research, 2012, Volume: 34, Issue:3 Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Chemoradiotherapy; Combined Modality Therapy; Disease Models, Animal; Disease Progression; Glioblastoma; Indoles; Mice; Mice, Transgenic; Pyrroles; Radiation Dosage; Sunitinib	2012
Resistance of glioblastoma-initiating cells to radiation mediated by the tumor microenvironment can be abolished by inhibiting transforming growth factor-β. Cancer research, 2012, Aug-15, Volume: 72, Issue:16 Topics: Animals; Antibodies, Neutralizing; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; DNA Damage; DNA, Neoplasm; Female; Glioblastoma; Humans; Mice; Mice, Inbred C57BL; Mink; Neoplastic Stem Cells; Neural Stem Cells; Pyrazoles; Pyrroles; Radiation Tolerance; Radiation-Sensitizing Agents; Signal Transduction; Transforming Growth Factor beta; Tumor Microenvironment	2012
Imaging biomarker dynamics in an intracranial murine glioma study of radiation and antiangiogenic therapy. International journal of radiation oncology, biology, physics, 2013, Mar-01, Volume: 85, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; Combined Modality Therapy; Diffusion Magnetic Resonance Imaging; Glioma; Indoles; Mice; Mice, Inbred NOD; Mice, SCID; Pyrroles; Radiotherapy, Conformal; Sunitinib; Tumor Burden	2013
Evaluation of tyrosine kinase inhibitor combinations for glioblastoma therapy. PloS one, 2012, Volume: 7, Issue:10 Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Drug Evaluation, Preclinical; Drug Synergism; Female; Gefitinib; Glioblastoma; Humans; Immunoblotting; Indoles; Inhibitory Concentration 50; Mice; Mice, Nude; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrroles; Quinazolines; Rats, Inbred F344; Spheroids, Cellular; Sunitinib; Treatment Outcome; Xenograft Model Antitumor Assays	2012
MicroRNA-21 silencing enhances the cytotoxic effect of the antiangiogenic drug sunitinib in glioblastoma. Human molecular genetics, 2013, Mar-01, Volume: 22, Issue:5 Topics: Angiogenesis Inhibitors; Animals; Apoptosis Regulatory Proteins; Brain Neoplasms; Cell Line, Tumor; Cell Proliferation; Down-Regulation; Gene Expression Regulation, Neoplastic; Glioblastoma; Humans; Indoles; Mice; MicroRNAs; PTEN Phosphohydrolase; Pyrroles; RNA-Binding Proteins; Signal Transduction; Sunitinib; Up-Regulation	2013
Do anti-angiogenic therapies prevent brain metastases in advanced renal cell carcinoma? Bulletin du cancer, 2012, Volume: 99, Issue:12 Topics: Adult; Aged; Aged, 80 and over; Alkaline Phosphatase; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Benzenesulfonates; Bevacizumab; Brain Neoplasms; Cancer Care Facilities; Carcinoma, Renal Cell; Everolimus; Female; France; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Proportional Hazards Models; Pyridines; Pyrroles; Retrospective Studies; Risk Factors; Sirolimus; Sorafenib; Sunitinib; Treatment Outcome	2012
Brain metastases from renal cell carcinoma in the era of tyrosine kinase inhibitors. Clinical genitourinary cancer, 2013, Volume: 11, Issue:2 Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Blood-Brain Barrier; Brain; Brain Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Male; Mice; Mice, Knockout; Middle Aged; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyrroles; Retrospective Studies; Sorafenib; Sunitinib; Treatment Outcome	2013
Influence of VEGF-R2 inhibition on MMP secretion and motility of microvascular human cerebral endothelial cells (HCEC). Journal of neuro-oncology, 2003, Volume: 62, Issue:3 Topics: Angiogenesis Inhibitors; Brain Neoplasms; Cell Movement; Cerebral Cortex; Endothelium, Vascular; Enzyme-Linked Immunosorbent Assay; Glioblastoma; Humans; Immunoenzyme Techniques; In Vitro Techniques; Indoles; Interleukin-10; Matrix Metalloproteinases; Microcirculation; Neovascularization, Pathologic; Protein-Tyrosine Kinases; Pyrroles; Spheroids, Cellular; Tumor Cells, Cultured; Umbilical Veins; Vascular Endothelial Growth Factor Receptor-2	2003
THE METABOLISM AND EXCRETION OF CO57 TETRAPHENYLPORPHINESULFONATE IN CANCER PATIENTS. Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1964, Volume: 5 Topics: Abdominal Neoplasms; Brain Neoplasms; Cobalt Isotopes; Humans; Metabolism; Neoplasms; Pyrroles; Radiometry	1964
Combined inhibition of vascular endothelial growth factor and platelet-derived growth factor signaling: effects on the angiogenesis, microcirculation, and growth of orthotopic malignant gliomas. Journal of neurosurgery, 2005, Volume: 102, Issue:2 Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Cell Division; Cell Line, Tumor; Cell Transformation, Neoplastic; Glioma; Indoles; Mice; Mice, Nude; Microcirculation; Microscopy, Fluorescence; Microscopy, Video; Neoplasm Transplantation; Neovascularization, Pathologic; Oxindoles; Platelet-Derived Growth Factor; Propionates; Protein-Tyrosine Kinases; Pyrroles; Rats; Receptor, Platelet-Derived Growth Factor beta; Signal Transduction; Transplantation, Heterologous; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2	2005
Down-regulation of insulin-like growth factor I receptor activity by NVP-AEW541 has an antitumor effect on neuroblastoma cells in vitro and in vivo. Clinical cancer research : an official journal of the American Association for Cancer Research, 2006, Nov-15, Volume: 12, Issue:22 Topics: Adrenal Gland Neoplasms; Animals; Antineoplastic Agents; Brain Neoplasms; Cell Proliferation; Down-Regulation; Humans; Kidney Neoplasms; Male; Mice; Mice, Nude; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Invasiveness; Neuroblastoma; Phosphorylation; Proto-Oncogene Proteins c-akt; Pyrimidines; Pyrroles; Receptor, IGF Type 1; Transplantation, Heterologous; Tumor Burden; Tumor Cells, Cultured; Xenograft Model Antitumor Assays	2006
Antiangiogenic and anti-invasive effects of sunitinib on experimental human glioblastoma. Neuro-oncology, 2007, Volume: 9, Issue:4 Topics: Angiogenesis Inhibitors; Animals; Blotting, Western; Brain; Brain Neoplasms; Cell Line, Tumor; Flow Cytometry; Focal Adhesion Protein-Tyrosine Kinases; Glioblastoma; Humans; Immunohistochemistry; Immunoprecipitation; Indoles; Mice; Mice, Nude; Neoplasm Invasiveness; Neoplasm Transplantation; Neovascularization, Pathologic; Organ Culture Techniques; Phosphorylation; Pyrroles; src-Family Kinases; Sunitinib; Xenograft Model Antitumor Assays	2007
Regression of brain metastases of renal cell carcinoma with antiangiogenic therapy. Journal of neuro-oncology, 2008, Volume: 86, Issue:2 Topics: Angiogenesis Inhibitors; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Female; Humans; Indoles; Kidney Neoplasms; Middle Aged; Neovascularization, Pathologic; Pyrroles; Sunitinib; Treatment Outcome	2008
Complete cerebral response with sunitinib for metastatic renal cell carcinoma. Annals of oncology : official journal of the European Society for Medical Oncology, 2007, Volume: 18, Issue:7 Topics: Aged; Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Lung Neoplasms; Magnetic Resonance Imaging; Male; Neoplasm Recurrence, Local; Pyrroles; Sunitinib	2007
High frequency of intracerebral hemorrhage in metastatic renal carcinoma patients with brain metastases treated with tyrosine kinase inhibitors targeting the vascular endothelial growth factor receptor. European urology, 2008, Volume: 53, Issue:2 Topics: Adult; Aged; Benzenesulfonates; Brain Neoplasms; Carcinoma, Renal Cell; Cerebral Hemorrhage; Female; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Niacinamide; Phenylurea Compounds; Protein Kinase Inhibitors; Pyridines; Pyrroles; Receptors, Vascular Endothelial Growth Factor; Sorafenib; Sunitinib	2008
Brain metastases in patients with renal cell cancer receiving new targeted treatment. Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 2008, Jan-01, Volume: 26, Issue:1 Topics: Antineoplastic Agents; Brain Neoplasms; Carcinoma, Renal Cell; Humans; Indoles; Kidney Neoplasms; Male; Middle Aged; Prognosis; Pyrroles; Sunitinib; Treatment Outcome	2008
In vitro antitumor activity of cromakalim in human brain tumor cells. Pharmacology, 1994, Volume: 49, Issue:2 Topics: Antineoplastic Agents; Astrocytoma; Benzopyrans; Brain; Brain Neoplasms; Calcium; Cell Survival; Cromakalim; Dose-Response Relationship, Drug; Humans; Neuroblastoma; Potassium Channels; Pyrroles; Sulfonylurea Compounds; Tumor Cells, Cultured	1994
Magnetic resonance imaging of ethyl-nitrosourea-induced rat gliomas: a model for experimental therapeutics of low-grade gliomas. Journal of neuro-oncology, 2001, Volume: 53, Issue:3 Topics: Angiogenesis Inhibitors; Animals; Brain Neoplasms; Carcinogens; Diet; Disease Models, Animal; Diterpenes; Ethylnitrosourea; Glioma; Indoles; Magnetic Resonance Imaging; Neoplasms, Multiple Primary; Neoplasms, Second Primary; Pyrroles; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Retinyl Esters; Survival Analysis; Time Factors; Vitamin A	2001
Flk-1 specific kinase inhibitor (SU5416) inhibited the growth of GS-9L glioma in rat brain and prolonged the survival. The Kobe journal of medical sciences, 2001, Volume: 47, Issue:4 Topics: Animals; Apoptosis; Brain; Brain Neoplasms; Enzyme Inhibitors; Glioma; Indoles; Male; Microcirculation; Pyrroles; Rats; Rats, Inbred F344; Receptor Protein-Tyrosine Kinases; Receptors, Growth Factor; Receptors, Vascular Endothelial Growth Factor; Survival Rate	2001