Page last updated: 2024-08-18

pyrroles and Brain Injuries

pyrroles has been researched along with Brain Injuries in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's14 (53.85)29.6817
2010's9 (34.62)24.3611
2020's3 (11.54)2.80

Authors

AuthorsStudies
Gao, X; Han, Z; Lei, P; Li, M; Li, X; Liu, M; Liu, Q; Zhang, W1
Boehm-Sturm, P; Brandenburg, S; Heinz, R; Kremenetskaia, I; Nieminen-Kelhä, M; Schneider, UC; Vajkoczy, P1
Cui, H; Gao, L; Yang, L1
Chen, D; Shen, J; Tan, T; Tu, L; Wang, S; Wang, Y1
Chapman, J; Itzekson, Z; Maggio, N; Milman, A; Pick, CG; Shavit, E1
Arora, RP; Green, KN; Hernandez, MX; Lee, RJ; Rice, RA; Spangenberg, EE; Tenner, AJ; West, BL; Yamate-Morgan, H1
Beskonakl i, E; Bodur, E; Eroglu, H; Gurcan, O; Okutan, O; Oner, L; Sargon, MF; Turkoglu, OF1
Cheng, G; Shi-Guang, Z; Wei, L; Xiang-Zhen, L; Zhi-Dan, S1
Agoston, DV; Lee, C2
Chang, YC; Huang, CC; Lee, HT; Tu, YF1
Hisanaga, S; Kawamura, K; Kawano, H; Kimura-Kuroda, J; Saito, T; Yoshioka, N1
Chen, B; Cheng, Q; Friedman, B; Lei, IF; Lyden, PD; Olson, ES; Pereira, B; Tsien, RY; Whitney, MA; Winkle, JA; Zhao, L1
Chen, J; Jiang, R; Li, Z; Sun, L; Tian, Y; Wang, B; Wang, D; Wei, H; Yang, Z; Zhang, J1
Kim, CH; Ma, Q; Manaenko, A; Sun, X; Yan, J; Zhang, JH1
Chen, J; Chopp, M; Goussev, A; Li, Y; Lu, D; Mahmood, A; Pannu, P1
Chopp, M; Goussev, A; Li, Y; Lu, D; Lu, M; Mahmood, A; Qu, C; Schallert, T; Zhang, ZG1
Chopp, M; Goussev, A; Lu, D; Lu, M; Mahmood, A; Qu, C1
Laskowitz, DT; Lynch, JR; McGirt, MJ; Woodworth, GF1
Chopp, M; Goussev, A; Lu, D; Mahmood, A; Qu, C; Zhang, ZG1
Chopp, M; Goussev, A; Lu, D; Mahmood, A; Qu, C; Schallert, T1
Holmin, S; Risling, M; Sköld, MK1
Chopp, M; Goussev, A; Lu, D; Mahmood, A; Qu, C1
Guyton, JR; Laskowitz, DT; Lynch, JR; Mace, B; Song, P; Wang, H; Warner, DS; Yang, HJ; Yates, RB1
Chen, J; Chopp, M; Goussev, A; Jiang, H; Li, Y; Lu, C; Lu, D; Mahmood, A; Qu, C; Schallert, T1
Burmester, GR; Buttgereit, F; Fici, G; Schmid, D; Tripmacher, R; von Voigtlander, P1

Other Studies

26 other study(ies) available for pyrroles and Brain Injuries

ArticleYear
Microglial replacement in the aged brain restricts neuroinflammation following intracerebral hemorrhage.
    Cell death & disease, 2022, 01-10, Volume: 13, Issue:1

    Topics: Aging; Aminopyridines; Animals; Blood-Brain Barrier; Brain; Brain Injuries; Cell Death; Cerebral Hemorrhage; Chemotaxis, Leukocyte; Disease Models, Animal; Mice; Microglia; Neuroinflammatory Diseases; Pyrroles; Receptors, Granulocyte-Macrophage Colony-Stimulating Factor

2022
Microglia as target for anti-inflammatory approaches to prevent secondary brain injury after subarachnoid hemorrhage (SAH).
    Journal of neuroinflammation, 2021, Jan-30, Volume: 18, Issue:1

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents; Brain Injuries; Ischemic Preconditioning; Mice; Mice, Inbred C57BL; Microglia; Pyrroles; Subarachnoid Hemorrhage

2021
GSK-3β inhibitor TWS119 alleviates hypoxic-ischemic brain damage via a crosstalk with Wnt and Notch signaling pathways in neonatal rats.
    Brain research, 2021, 10-01, Volume: 1768

    Topics: Animals; Animals, Newborn; Brain; Brain Injuries; Female; Glycogen Synthase Kinase 3 beta; Hypoxia-Ischemia, Brain; Male; Models, Animal; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Notch; Signal Transduction; Wnt Signaling Pathway

2021
TRPV4 channels stimulate Ca
    Brain research bulletin, 2019, Volume: 146

    Topics: Animals; Apoptosis; Brain Injuries; Calcium; Cell Death; Cell Survival; Cerebral Hemorrhage; Endoplasmic Reticulum Stress; Inositol 1,4,5-Trisphosphate Receptors; Leucine; Male; Mice; Mice, Inbred C57BL; Morpholines; Neurons; Pyrroles; Sulfonamides; TRPV Cation Channels; Unfolded Protein Response

2019
Reversal of trauma-induced amnesia in mice by a thrombin receptor antagonist.
    Journal of molecular neuroscience : MN, 2014, Volume: 53, Issue:1

    Topics: Amnesia; Animals; Brain Injuries; Hippocampus; Long-Term Potentiation; Mice; Mice, Inbred ICR; Pyrroles; Quinazolines; Receptor, PAR-1; Thrombin

2014
Elimination of Microglia Improves Functional Outcomes Following Extensive Neuronal Loss in the Hippocampus.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015, Jul-08, Volume: 35, Issue:27

    Topics: Aminopyridines; Animals; Behavioral Symptoms; Blood-Brain Barrier; Brain Injuries; Cognition Disorders; Dendritic Spines; Disease Models, Animal; Doxycycline; Female; Hippocampus; Male; Maze Learning; Mice; Mice, Transgenic; Microglia; Neurons; Phosphopyruvate Hydratase; Pyrroles; Recovery of Function; Synaptophysin

2015
Atorvastatin efficiency after traumatic brain injury in rats.
    Surgical neurology, 2009, Volume: 72, Issue:2

    Topics: Analysis of Variance; Animals; Atorvastatin; Brain; Brain Edema; Brain Injuries; Cerebrovascular Circulation; Craniotomy; Disease Models, Animal; Heptanoic Acids; Lipid Peroxidation; Male; Microcirculation; Microscopy, Electron, Transmission; Neuroprotective Agents; Organ Size; Pyrroles; Random Allocation; Rats; Rats, Sprague-Dawley

2009
Atorvastatin ameliorates cerebral vasospasm and early brain injury after subarachnoid hemorrhage and inhibits caspase-dependent apoptosis pathway.
    BMC neuroscience, 2009, Jan-21, Volume: 10

    Topics: Animals; Apoptosis; Atorvastatin; Blood-Brain Barrier; Brain; Brain Edema; Brain Injuries; Caspases; DNA Fragmentation; Heptanoic Acids; Male; Neuroprotective Agents; Pyrroles; Rats; Rats, Sprague-Dawley; RNA, Messenger; Subarachnoid Hemorrhage; Vasospasm, Intracranial; Water

2009
Inhibition of VEGF receptor 2 increased cell death of dentate hilar neurons after traumatic brain injury.
    Experimental neurology, 2009, Volume: 220, Issue:2

    Topics: Animals; Brain Injuries; Cell Death; Dentate Gyrus; Fluoresceins; Fluorescent Dyes; Immunohistochemistry; In Situ Nick-End Labeling; Indoles; Injections, Intraventricular; Male; Neurons; Neuroprotective Agents; Organic Chemicals; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2009
Vascular endothelial growth factor is involved in mediating increased de novo hippocampal neurogenesis in response to traumatic brain injury.
    Journal of neurotrauma, 2010, Volume: 27, Issue:3

    Topics: Animals; Biomarkers; Brain Injuries; Bromodeoxyuridine; Cell Death; Cell Proliferation; Disease Models, Animal; Doublecortin Domain Proteins; Hippocampus; In Situ Nick-End Labeling; Indoles; Infusion Pumps, Implantable; Male; Microtubule-Associated Proteins; Nerve Regeneration; Neurogenesis; Neuropeptides; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Sprague-Dawley; Recovery of Function; Stem Cells; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2010
CREB activation mediates VEGF-A's protection of neurons and cerebral vascular endothelial cells.
    Journal of neurochemistry, 2010, Volume: 113, Issue:1

    Topics: Animals; Animals, Newborn; Brain Injuries; Cell Survival; Cells, Cultured; Chromones; CREB-Binding Protein; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelial Cells; Enzyme Inhibitors; Extracellular Signal-Regulated MAP Kinases; Glial Fibrillary Acidic Protein; Glucose; Hypoxia; Hypoxia-Ischemia, Brain; Indoles; Injections, Intraventricular; Male; Morpholines; Neurons; Phosphorylation; Placenta Growth Factor; Platelet Endothelial Cell Adhesion Molecule-1; Pregnancy Proteins; Pyrroles; Rats; Rats, Sprague-Dawley; Serine; Signal Transduction; Time Factors; Transfection; Up-Regulation; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2010
Small molecule inhibitor of type I transforming growth factor-β receptor kinase ameliorates the inhibitory milieu in injured brain and promotes regeneration of nigrostriatal dopaminergic axons.
    Journal of neuroscience research, 2011, Volume: 89, Issue:3

    Topics: Animals; Antigens; Axons; Brain Injuries; Cicatrix; Corpus Striatum; Disease Models, Animal; Enzyme Inhibitors; Glial Fibrillary Acidic Protein; Leukocyte Common Antigens; Male; Mice; Mice, Inbred ICR; Nerve Regeneration; Protein Serine-Threonine Kinases; Proteoglycans; Pyrazoles; Pyrroles; Receptor, Transforming Growth Factor-beta Type I; Receptors, Transforming Growth Factor beta; Signal Transduction; Smad2 Protein; Substantia Nigra; Tyrosine 3-Monooxygenase

2011
Thrombin activity associated with neuronal damage during acute focal ischemia.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012, May-30, Volume: 32, Issue:22

    Topics: Amino Acids; Analysis of Variance; Animals; Antithrombins; Arginine; Avoidance Learning; Brain Injuries; Cell Death; Cognition Disorders; Disease Models, Animal; Factor X; Fibrinolysin; Gene Expression Regulation; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Male; Maze Learning; Motor Activity; Nerve Tissue Proteins; Pipecolic Acids; Pyrroles; Rats; Reaction Time; Receptor, PAR-1; Sulfonamides; Thrombin; Time Factors

2012
Effects of atorvastatin in the regulation of circulating EPCs and angiogenesis in traumatic brain injury in rats.
    Journal of the neurological sciences, 2012, Aug-15, Volume: 319, Issue:1-2

    Topics: Animals; Atorvastatin; Brain Injuries; Endothelial Cells; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Long-Term Potentiation; Male; Maze Learning; Neovascularization, Pathologic; Pyrroles; Rats; Rats, Wistar; Recovery of Function; Stem Cells

2012
PAR-1 antagonist SCH79797 ameliorates apoptosis following surgical brain injury through inhibition of ASK1-JNK in rats.
    Neurobiology of disease, 2013, Volume: 50

    Topics: Animals; Apoptosis; Blotting, Western; Brain; Brain Edema; Brain Injuries; Immunohistochemistry; Intraoperative Complications; Male; MAP Kinase Kinase 4; MAP Kinase Kinase Kinase 5; Neurosurgical Procedures; Pyrroles; Quinazolines; Rats; Rats, Sprague-Dawley; Receptor, PAR-1; Thrombin

2013
Atorvastatin reduces neurological deficit and increases synaptogenesis, angiogenesis, and neuronal survival in rats subjected to traumatic brain injury.
    Journal of neurotrauma, 2004, Volume: 21, Issue:1

    Topics: Administration, Oral; Animals; Atorvastatin; Brain; Brain Injuries; Cell Survival; Disease Models, Animal; Heptanoic Acids; Immunohistochemistry; Male; Neovascularization, Physiologic; Neurons; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Synapses; Synaptophysin

2004
Atorvastatin reduction of intravascular thrombosis, increase in cerebral microvascular patency and integrity, and enhancement of spatial learning in rats subjected to traumatic brain injury.
    Journal of neurosurgery, 2004, Volume: 101, Issue:5

    Topics: Animals; Atorvastatin; Brain Injuries; Cerebral Cortex; Cerebrovascular Circulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Memory; Microcirculation; Pyrroles; Rats; Rats, Wistar; Thrombin; Vascular Patency

2004
Atorvastatin reduction of intracranial hematoma volume in rats subjected to controlled cortical impact.
    Journal of neurosurgery, 2004, Volume: 101, Issue:5

    Topics: Animals; Atorvastatin; Brain Injuries; Cerebral Cortex; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Hemorrhage, Traumatic; Male; Pyrroles; Rats; Rats, Wistar

2004
Synthes Award for Resident Research in Spinal Cord & Spinal Column Injury: Statins for the treatment of neurological injury: a role beyond cholesterol lowering.
    Clinical neurosurgery, 2004, Volume: 51

    Topics: Animals; Anticholesteremic Agents; Atorvastatin; Awards and Prizes; Brain Injuries; Heptanoic Acids; Hypercholesterolemia; Immunoblotting; Interleukin-6; Internship and Residency; Mice; Pyrroles; Research; RNA, Messenger; Simvastatin; Spinal Cord Injuries; Subarachnoid Hemorrhage

2004
Delayed thrombosis after traumatic brain injury in rats.
    Journal of neurotrauma, 2004, Volume: 21, Issue:12

    Topics: Animals; Atorvastatin; Blood Coagulation Factors; Brain; Brain Injuries; Disease Models, Animal; Fibrin; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Intracranial Thrombosis; Male; Pyrroles; Rats; Rats, Wistar; Time Factors

2004
Effect of atorvastatin on spatial memory, neuronal survival, and vascular density in female rats after traumatic brain injury.
    Journal of neurosurgery, 2005, Volume: 103, Issue:4

    Topics: Administration, Oral; Animals; Anticholesteremic Agents; Atorvastatin; Brain Injuries; Cell Survival; Female; Heptanoic Acids; Immunohistochemistry; Memory; Neovascularization, Physiologic; Neurons; Pyrroles; Rats; Rats, Wistar; Reproducibility of Results; Sex Factors

2005
Inhibition of vascular endothelial growth factor receptor 2 activity in experimental brain contusions aggravates injury outcome and leads to early increased neuronal and glial degeneration.
    The European journal of neuroscience, 2006, Volume: 23, Issue:1

    Topics: Angiogenesis Inhibitors; Animals; Brain Injuries; Cell Count; Cell Death; Disease Models, Animal; Female; Fluoresceins; Glial Fibrillary Acidic Protein; Immunosorbent Techniques; In Situ Hybridization; In Situ Nick-End Labeling; Indoles; Microtubule-Associated Proteins; Myelin-Associated Glycoprotein; Nerve Degeneration; Nerve Growth Factors; Neuroglia; Organic Chemicals; Pyrroles; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein beta Subunit; S100 Proteins; Time Factors; Vascular Endothelial Growth Factor Receptor-2

2006
Treatment of traumatic brain injury with a combination therapy of marrow stromal cells and atorvastatin in rats.
    Neurosurgery, 2007, Volume: 60, Issue:3

    Topics: Animals; Atorvastatin; Bone Marrow Transplantation; Brain Injuries; Combined Modality Therapy; Female; Hematopoietic Stem Cell Transplantation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; Rats; Rats, Wistar; Stromal Cells; Treatment Outcome

2007
Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.
    Experimental neurology, 2007, Volume: 206, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Atorvastatin; Brain Edema; Brain Injuries; Brain Ischemia; Cerebrovascular Circulation; Chemotaxis, Leukocyte; Cognition Disorders; Cytokines; Disease Models, Animal; Encephalitis; Endothelial Cells; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Mice; Mice, Inbred C57BL; Nerve Degeneration; Neurons; Pyrroles; Recovery of Function; RNA, Messenger; Simvastatin; Treatment Outcome

2007
Statins increase neurogenesis in the dentate gyrus, reduce delayed neuronal death in the hippocampal CA3 region, and improve spatial learning in rat after traumatic brain injury.
    Journal of neurotrauma, 2007, Volume: 24, Issue:7

    Topics: Animals; Atorvastatin; Brain Injuries; Cell Proliferation; Dentate Gyrus; Dose-Response Relationship, Drug; Heptanoic Acids; Hippocampus; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Maze Learning; Memory Disorders; Neovascularization, Physiologic; Nerve Degeneration; Nerve Regeneration; Neuronal Plasticity; Neurons; Neuroprotective Agents; Pyrroles; Rats; Rats, Wistar; Recovery of Function; Simvastatin; Stem Cells; Treatment Outcome

2007
Short-term effects of the 21-aminosteroid lazaroid tirilazad mesylate (PNU-74006F) and the pyrrolopyrimidine lazaroid PNU-101033E on energy metabolism of human peripheral blood mononuclear cells.
    Bioscience reports, 2001, Volume: 21, Issue:1

    Topics: Adenosine Triphosphate; Anti-Inflammatory Agents; Brain Injuries; Calcium-Transporting ATPases; Cell Membrane; Cell Respiration; Concanavalin A; Dose-Response Relationship, Drug; Energy Metabolism; Enzyme Inhibitors; Humans; Leukocytes, Mononuclear; Lipid Peroxidation; Methylprednisolone; Neuroprotective Agents; Pregnatrienes; Protein Biosynthesis; Proteins; Pyrimidines; Pyrroles; Sodium-Potassium-Exchanging ATPase; Time Factors

2001