pyrroles has been researched along with Blast Crisis in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (60.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Burley, GA; Fang, L; Gómez-Castañeda, E; Hayatigolkhatmi, K; Hsieh, YC; Jackson, L; Jørgensen, HG; Padroni, G; Pellicano, F; Su, W | 1 |
| Borthakur, G; Carter, TH; Claxton, D; DeAngelo, DJ; Erba, H; Goard, C; Raza, A; Schimmer, AD; Tallman, MS | 1 |
| Bello, C; Berdel, WE; Cherrington, JM; Cooper, MA; Fiedler, W; Foran, JM; Heinrich, MC; Jacobs, M; Kelsey, S; Kim, H; Louie, SG; Manning, WC; Nicholas, S; O'Farrell, AM; Paquette, RL; Scigalla, P; Serve, H; Yuen, HA | 1 |
| Galski, H; Lazarovici, P; Nagler, A; Sivan, H | 1 |
| Mahadevan, D | 1 |
2 trial(s) available for pyrroles and Blast Crisis
| Article | Year |
|---|---|
A multicenter phase I/II study of obatoclax mesylate administered as a 3- or 24-hour infusion in older patients with previously untreated acute myeloid leukemia.
Topics: Aged; Aged, 80 and over; Blast Crisis; Demography; Drug Administration Schedule; Female; Humans; Indoles; Leukemia, Myeloid, Acute; Male; Neutrophils; Platelet Count; Pyrroles; Treatment Outcome | 2014 |
An innovative phase I clinical study demonstrates inhibition of FLT3 phosphorylation by SU11248 in acute myeloid leukemia patients.
Topics: Administration, Oral; Adult; Aged; Blast Crisis; Enzyme Inhibitors; Female; fms-Like Tyrosine Kinase 3; Genotype; Humans; Indoles; Leukemia, Myeloid, Acute; Male; Metabolic Clearance Rate; Middle Aged; Mitogen-Activated Protein Kinases; Phosphorylation; Proto-Oncogene Proteins; Pyrroles; Receptor Protein-Tyrosine Kinases; Sunitinib | 2003 |
3 other study(ies) available for pyrroles and Blast Crisis
| Article | Year |
|---|---|
An investigation of targeted inhibition of transcription factor activity with pyrrole imidazole polyamide (PA) in chronic myeloid leukemia (CML) blast crisis cells.
Topics: Antineoplastic Agents; Blast Crisis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; E2F1 Transcription Factor; Humans; Imidazoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Molecular Structure; Nylons; Protein Kinase Inhibitors; Pyrroles; Structure-Activity Relationship | 2019 |
In vitro and in vivo reversal of MDR1-mediated multidrug resistance by KT-5720: implications on hematological malignancies.
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Carbazoles; Cell Line, Tumor; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Mice, Transgenic; Multiple Myeloma; Pyrroles | 2006 |
Will MDR-1/P-gp modulators provide clinical benefit in hematologic malignancies?
Topics: Animals; Antibiotics, Antineoplastic; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blast Crisis; Carbazoles; Cell Line, Tumor; Daunorubicin; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Humans; Indoles; Leukemia, Myelogenous, Chronic, BCR-ABL Positive; Mice; Mice, Inbred BALB C; Mice, Transgenic; Multiple Myeloma; Pyrroles | 2006 |