Page last updated: 2024-08-18

pyrroles and B-Cell Lymphoma

pyrroles has been researched along with B-Cell Lymphoma in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (14.29)29.6817
2010's9 (64.29)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Bao, Y; Chen, Z; Lin, J; Lu, L; Shu, Y; Sun, N; Wang, Y; Xie, Q; Zhao, Y1
Cao, ZR; Chen, Y; Chen, ZQ; Ding, J; Meng, LH; Wang, Y; Wang, YX; Xu, L; Yang, CH; Zhang, X1
Changou, CA; Chen, CL; Chen, YP; Chuang, EY; Hung, YP; Jhan, MK; Lai, CY; Lee, CM; Lin, CF; Nguyen, TT; Tseng, PC; Wang, YT1
Ardeshna, KM; Boni, J; Caimi, P; Carlo-Stella, C; Feingold, JM; Hamadani, M; Havenith, K; He, S; Heffner, LT; Kahl, BS; O'Connor, OA; Radford, J; Reid, E; Solh, M; Ungar, D1
Amato, R; Fallacara, AL; Giacchello, I; Greco, C; Musumeci, F; Sanna, M; Schenone, S1
Benjamin, D; Gordon, KA; Kostner, H; Meyer, B; Palanca-Wessels, MC; Ryan, MC; Schimpf, B; Van Epps, HA; Yu, C1
Ball, DJ; Bowman, CJ; Collinge, M; Nilson, AL; Radi, ZA; Vogel, WM1
Barr, PM; Boyd, T; Caimi, PF; Carret, AS; Chen, R; Chhabra, S; Gartner, EM; Kingsley, EC; Kolibaba, K; Li, H; Park, SI; Phillips, T; Smith, DC; Yu, C1
Bahleda, R; Escudier, B; Gueutin, V; Izzedine, H; Rouvier, P; Soria, JC; Varga, A1
Dervan, PB; Kang, JS1
Chang, X; Song, T; Wu, G; Xie, F; Zhang, Z1
Bhat, S; Brem, EA; Campagna, R; Czuczman, MS; Deeb, G; Fetterly, G; Gibbs, JF; Gu, J; Hernandez-Ilizaliturri, FJ; Hoskin, P; Iqbal, A; Khubchandani, S; Knight, J; Mavis, C; Olejniczak, SH; Riaz, W; Thudium, K; Tsai, PC1
Chae, K; Guo, B; Humphries, LA; Kang, S; Kato, RM; Kawakami, T; Kawakami, Y; Leitges, M; Patrone, L; Rawlings, DJ; Sommer, K; Su, TT; Teitell, M; Wall, R1
Ahmad, I; Borisch, B; Burdevet, D; Din, NU; Ding, H; Hoessli, DC; Khatib, K; Lindquist, JA; Schraven, B; Tauzin, S; van Echten-Deckert, G1

Reviews

2 review(s) available for pyrroles and B-Cell Lymphoma

ArticleYear
Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors.
    Expert opinion on therapeutic patents, 2017, Volume: 27, Issue:12

    Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Autoimmune Diseases; Drug Design; Humans; Leukemia, B-Cell; Lymphoma, B-Cell; Patents as Topic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles

2017
A sequence-specific DNA binding small molecule triggers the release of immunogenic signals and phagocytosis in a model of B-cell lymphoma.
    Quarterly reviews of biophysics, 2015, Volume: 48, Issue:4

    Topics: Adenosine Triphosphate; Animals; Calreticulin; DNA; Enzyme-Linked Immunosorbent Assay; HMGB1 Protein; Humans; Imidazoles; Immunoblotting; Inflammation; K562 Cells; Luminescence; Lymphoma, B-Cell; Macrophages; Necrosis; Neoplasms; Nylons; Phagocytosis; Pyrroles; Signal Transduction; Telomere; Up-Regulation

2015

Trials

2 trial(s) available for pyrroles and B-Cell Lymphoma

ArticleYear
A Phase I Study of ADCT-402 (Loncastuximab Tesirine), a Novel Pyrrolobenzodiazepine-Based Antibody-Drug Conjugate, in Relapsed/Refractory B-Cell Non-Hodgkin Lymphoma.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2019, 12-01, Volume: 25, Issue:23

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antigens, CD19; Antineoplastic Agents; Benzodiazepines; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Humans; Immunoconjugates; Lymphoma, B-Cell; Male; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Pyrroles; Salvage Therapy; Survival Rate; Young Adult

2019
A phase 1 trial of SGN-CD70A in patients with CD70-positive diffuse large B cell lymphoma and mantle cell lymphoma.
    Investigational new drugs, 2019, Volume: 37, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Antibodies, Monoclonal; Benzodiazepines; Biomarkers, Tumor; CD27 Ligand; Drug Resistance, Neoplasm; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Immunoconjugates; Lymphoma, B-Cell; Lymphoma, Large B-Cell, Diffuse; Lymphoma, Mantle-Cell; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Recurrence, Local; Prognosis; Pyrroles; Salvage Therapy; Tissue Distribution

2019

Other Studies

10 other study(ies) available for pyrroles and B-Cell Lymphoma

ArticleYear
Discovery of novel BTK PROTACs for B-Cell lymphomas.
    European journal of medicinal chemistry, 2021, Dec-05, Volume: 225

    Topics: Agammaglobulinaemia Tyrosine Kinase; Antineoplastic Agents; Cell Proliferation; Cells, Cultured; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Humans; Lymphoma, B-Cell; Molecular Structure; Protein Kinase Inhibitors; Proteolysis; Pyrans; Pyrimidines; Pyrroles; Structure-Activity Relationship

2021
Repressing MYC by targeting BET synergizes with selective inhibition of PI3Kα against B cell lymphoma.
    Cancer letters, 2022, 01-01, Volume: 524

    Topics: Acetanilides; Animals; Apoptosis; Cell Line, Tumor; Cell Proliferation; Class I Phosphatidylinositol 3-Kinases; Gene Expression Regulation, Neoplastic; Heterocyclic Compounds, 3-Ring; Histone Acetyltransferases; Humans; Lymphoma, B-Cell; Mice; Morpholines; Nerve Tissue Proteins; Phosphorylation; Piperazines; Proto-Oncogene Proteins c-myc; Pyrroles; Receptors, Cell Surface; Thiazoles; Xenograft Model Antitumor Assays

2022
Anticancer polypyrrole-polyethylenimine drug-free nanozyme for precise B-cell lymphoma therapy.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 160

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Humans; Lymphoma; Lymphoma, B-Cell; Mice; Polyethyleneimine; Polymers; Pyrroles; Tumor Microenvironment

2023
Therapeutic potential of SGN-CD19B, a PBD-based anti-CD19 drug conjugate, for treatment of B-cell malignancies.
    Blood, 2017, 11-02, Volume: 130, Issue:18

    Topics: Animals; Antibodies; Antigens, CD19; Benzodiazepines; Cell Cycle Checkpoints; Cell Line, Tumor; Cytotoxicity, Immunologic; Humans; Lymphoma, B-Cell; Macaca fascicularis; Mice, SCID; Pyrroles; Xenograft Model Antitumor Assays

2017
Immunologic effects of chronic administration of tofacitinib, a Janus kinase inhibitor, in cynomolgus monkeys and rats - Comparison of juvenile and adult responses.
    Regulatory toxicology and pharmacology : RTP, 2018, Volume: 94

    Topics: Administration, Oral; Aging; Animals; Antigens; Erythrocyte Count; Female; Hematocrit; Hemocyanins; Hemoglobins; Janus Kinase Inhibitors; Leukocyte Count; Leukocytes; Lymphoma, B-Cell; Macaca fascicularis; Male; Organ Size; Piperidines; Pyrimidines; Pyrroles; Rats, Sprague-Dawley; Spleen; Thymus Gland; Toxicity Tests, Chronic

2018
Acute tubular necrosis associated with mTOR inhibitor therapy: a real entity biopsy-proven.
    Annals of oncology : official journal of the European Society for Medical Oncology, 2013, Volume: 24, Issue:9

    Topics: Acute Kidney Injury; Adenocarcinoma; Adenocarcinoma of Lung; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Bone Density Conservation Agents; Carcinoma, Renal Cell; Cisplatin; Cyclophosphamide; Diphosphonates; Doxorubicin; Female; Glutamates; Guanine; Humans; Imidazoles; Indoles; Interferons; Kidney Tubules; Lung Neoplasms; Lymphoma, B-Cell; Male; Mediastinal Neoplasms; Middle Aged; Necrosis; Nephrectomy; Pemetrexed; Prednisone; Pyrroles; Sunitinib; TOR Serine-Threonine Kinases; Vincristine; Zoledronic Acid

2013
3-Thiomorpholin-8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile (S1) based molecules as potent, dual inhibitors of B-cell lymphoma 2 (Bcl-2) and myeloid cell leukemia sequence 1 (Mcl-1): structure-based design and structure-activity relationship studies.
    Journal of medicinal chemistry, 2011, Feb-24, Volume: 54, Issue:4

    Topics: Acenaphthenes; Antineoplastic Agents; Binding, Competitive; Cell Line, Tumor; Cell Survival; Humans; Inhibitory Concentration 50; Lymphoma, B-Cell; Magnetic Resonance Spectroscopy; Mass Spectrometry; Morpholines; Myeloid Cell Leukemia Sequence 1 Protein; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Structure-Activity Relationship

2011
Distinct cellular and therapeutic effects of obatoclax in rituximab-sensitive and -resistant lymphomas.
    British journal of haematology, 2011, Volume: 153, Issue:5

    Topics: Antibodies, Monoclonal, Murine-Derived; Antibody-Dependent Cell Cytotoxicity; Antineoplastic Combined Chemotherapy Protocols; Apoptosis Regulatory Proteins; Autophagy; bcl-2 Homologous Antagonist-Killer Protein; bcl-2-Associated X Protein; Caspases; Cell Death; Drug Evaluation, Preclinical; Drug Resistance, Neoplasm; Drug Synergism; Humans; Indoles; Lymphoma, B-Cell; Lymphoma, Follicular; Lymphoma, Large B-Cell, Diffuse; Neoplasm Proteins; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrroles; Rituximab; Tumor Cells, Cultured; Up-Regulation

2011
PKC-beta controls I kappa B kinase lipid raft recruitment and activation in response to BCR signaling.
    Nature immunology, 2002, Volume: 3, Issue:8

    Topics: Animals; Apoptosis; B-Lymphocytes; Enzyme Inhibitors; Flow Cytometry; I-kappa B Kinase; I-kappa B Proteins; Immunoblotting; Indoles; Isoenzymes; Lymphoma, B-Cell; Maleimides; Mesylates; Mice; Mice, Inbred BALB C; Mice, Knockout; NF-kappa B; Protein Kinase C; Protein Kinase C beta; Protein Serine-Threonine Kinases; Pyrroles; Receptors, Antigen, B-Cell; Signal Transduction

2002
Oncogenic association of the Cbp/PAG adaptor protein with the Lyn tyrosine kinase in human B-NHL rafts.
    Blood, 2008, Feb-15, Volume: 111, Issue:4

    Topics: Adaptor Proteins, Signal Transducing; Carrier Proteins; Cell Death; Cell Division; Cell Line, Tumor; Cell Survival; Corticosterone; Gene Silencing; Humans; Lymphoma, B-Cell; Membrane Microdomains; Membrane Proteins; Pyrimidines; Pyrroles; RNA, Small Interfering; src-Family Kinases; STAT3 Transcription Factor

2008