Page last updated: 2024-08-18

pyrroles and Autoimmune Disease

pyrroles has been researched along with Autoimmune Disease in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	14 (33.33)	29.6817
2010's	24 (57.14)	24.3611
2020's	4 (9.52)	2.80

Authors

Authors	Studies
Li, H; Liu, Z; Shu, J; Su, G; Xu, J; Yang, P; Zhou, C	1
Dhillon, S	1
Fan, T; He, X; Huang, X; Liu, R; Ruan, Q; Su, W; Wang, T; Wu, C	1
Moreker, MR	1
Amato, R; Fallacara, AL; Giacchello, I; Greco, C; Musumeci, F; Sanna, M; Schenone, S	1
Byun, S; Lee, E; Lee, KW	1
King, BA; Liu, LY	1
Arnold, EP; Banker, ME; Basak, A; Brown, MF; Casavant, JM; Caspers, N; Clark, JD; Dowty, ME; Duclos, BA; Fenwick, AE; Flanagan, ME; Griffin, SH; Han, S; Harris, TM; Heasley, SE; Hegen, M; Johnson, TA; Jussif, J; Kaila, N; Kwon, S; Langille, J; Li, L; Lin, TH; Mitton-Fry, MJ; Parikh, MD; Robinson, RP; Strohbach, JW; Symanowicz, PT; Telliez, JB; TenBrink, RE; Trzupek, JD; Unwalla, R; Vazquez, ML; Wang, L; Yang, X	1
Bitterman, A; Borbon, J; Cerise, J; Chen, JC; Christiano, AM; Clynes, R; Jabbari, A; Mackay-Wiggan, J; Sansaricq, F; Ulerio, G	1
Huang, F; Luo, ZC	1
Christiano, AM; Clynes, R; Dai, Z; de Jong, A; Duvic, M; Hordinsky, M; Jabbari, A; Lee, D; Li, MM; Mackay-Wiggan, J; Norris, DA; Price, V; Xing, L	1
Castañeda, S; Morell Baladrón, A; Serra López-Matencio, JM	1
Dina, Y; McKesey, J; Pandya, AG	1
Deodhar, A	1
Gadina, M; Ghoreschi, K	1
Aittomäki, S; Pesu, M	1
Waldmann, TA	1
Gadina, M	1
Clark, JD; Flanagan, ME; Telliez, JB	1
Liang, Y; Liu, YY; Pan, HF; Peng, H; Xia, Y; Xu, WD; Yang, XK; Ye, DQ; Zhu, Y	1
Krossnes, BK; Ljøstad, U; Mygland, Å	1
Dejaco, C; Fasching, P; Fessler, J; Graninger, W; Stradner, M	1
Alpert, C; Bays, N; Byford, A; Chakravarthy, K; Chiu, CS; Dandliker, PJ; Deshmukh, SV; Dinsmore, C; Dorosh, L; Elwood, F; Goldenblatt, P; Ivanovska, I; Kariv, I; Klappenbach, J; Kraybill, B; Lee, HH; Pan, BS; Piesvaux, J; Qu, Y; Rivkin, A; Scott, ME; Slipetz, D; Tang, H; Witter, DJ; Zielstorff, M	1
Famularo, G; Gasbarrone, L; Minisola, G	1
Blumenkopf, TA; Brissette, WH; Brown, MF; Casavant, JM; Changelian, PS; Doty, JL; Elliott, EA; Fisher, MB; Flanagan, ME; Hines, M; Kent, C; Kudlacz, EM; Lillie, BM; Magnuson, KS; McCurdy, SP; Munchhof, MJ; Perry, BD; Sawyer, PS; Shang-Poa, C; Strelevitz, TJ; Subramanyam, C; Sun, J; Whipple, DA	1
Arndt, JW; Biamonte, MA; Giza, K; Harning, EK; Kehry, MR; Li, P; Luchetti, D; Lundgren, K; Manning, A; Rabah, D; Shi, J; Yun, TJ	1
Gulati, P; Venkataramanan, R; Vijayakrishnan, L	1
Chastain, EM; Getts, DR; Getts, MT; Martin, A; Miller, SD; Shankar, S; Wood, K	1
Ceppa, P; Indiveri, F; Pelli, N; Setti, M; Toncini, C	1
Mach, F	1
Adamson, P; Baker, D; Calder, V; Gegg, M; Greenwood, J; Hankey, D; Harry, R; Pryce, G; Zambarakji, H	1
Albini, T; Evans, M; Giri, RK; Rao, NA; See, RF; Thomas, PB	1
Van Buuren, HR; Wolters, LM	1
Taraseviciene-Stewart, L; Voelkel, N	1
Gao, C; Li, WM; Liu, W; Sun, NL	1
Brumeanu, TD; Casares, S; Goldstein, R	1
Gao, C; Li, WM; Liu, W; Zhou, BG	1
Kaupper, T; Walter, M; Ziegler, AG	1
Bookland, RG; Brugel, TA; Cabrera, EJ; Chen, J; Clark, MP; Davis, JR; De, B; Easwaran, V; George, KM; Golebiowski, A; Laufersweiler, MJ; Laughlin, SK; Lee, W; Maier, JA; Sabat, MP; Thakur, KD; VanRens, JC; Webster, ME; Zhang, G	1
Kitahara, K; Kohno, H; Okano, K; Saito, S; Sakai, T	1
Chen, L; Huang, J; Qian, H; Shen, D; Tang, Q; Wang, H; Wang, T; Wu, H; Xiong, R	1
Hidalgo, C; Jaimez, L; Jiménez-Alonso, J; Leon, L; Sabio, JM	1

Reviews

18 review(s) available for pyrroles and Autoimmune Disease

Article	Year
Delgocitinib: First Approval. Drugs, 2020, Volume: 80, Issue:6 Topics: Animals; Autoimmune Diseases; Drug Approval; Humans; Hypersensitivity; Janus Kinase Inhibitors; Janus Kinases; Molecular Conformation; Pyrroles	2020
Pyrrolo[2,3-d]pyrimidines active as Btk inhibitors. Expert opinion on therapeutic patents, 2017, Volume: 27, Issue:12 Topics: Agammaglobulinaemia Tyrosine Kinase; Animals; Autoimmune Diseases; Drug Design; Humans; Leukemia, B-Cell; Lymphoma, B-Cell; Patents as Topic; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrimidines; Pyrroles	2017
Therapeutic Implications of Autophagy Inducers in Immunological Disorders, Infection, and Cancer. International journal of molecular sciences, 2017, Sep-12, Volume: 18, Issue:9 Topics: Adaptive Immunity; Animals; Autoimmune Diseases; Autophagy; Benzylisoquinolines; Cholecalciferol; Humans; Immune System Diseases; Immunity, Innate; Indoles; Infections; Isoquinolines; Lysosomes; Maprotiline; Metformin; Neoplasms; Phenols; Pyrroles; Resveratrol; Sirolimus; Spermidine; Stilbenes; Tetrahydroisoquinolines; Trehalose	2017
Tofacitinib for the Treatment of Severe Alopecia Areata in Adults and Adolescents. The journal of investigative dermatology. Symposium proceedings, 2018, Volume: 19, Issue:1 Topics: Administration, Topical; Adolescent; Adult; Algorithms; Alopecia Areata; Autoimmune Diseases; Clinical Trials as Topic; Female; Humans; Janus Kinase Inhibitors; Male; Piperidines; Pyrimidines; Pyrroles	2018
Adverse drug events associated with 5mg versus 10mg Tofacitinib (Janus kinase inhibitor) twice daily for the treatment of autoimmune diseases: A systematic review and meta-analysis of randomized controlled trials. Clinical rheumatology, 2019, Volume: 38, Issue:2 Topics: Autoimmune Diseases; Dose-Response Relationship, Drug; Humans; Janus Kinase Inhibitors; Piperidines; Pyrimidines; Pyrroles; Randomized Controlled Trials as Topic; Treatment Outcome	2019
JAK-STAT inhibitors for the treatment of immunomediated diseases. Medicina clinica, 2019, 05-03, Volume: 152, Issue:9 Topics: Autoimmune Diseases; Azetidines; Humans; Immunologic Factors; Inflammatory Bowel Diseases; Janus Kinase Inhibitors; Piperidines; Purines; Pyrazoles; Pyrimidines; Pyrroles; STAT Transcription Factors; Sulfonamides	2019
Jakpot! New small molecules in autoimmune and inflammatory diseases. Experimental dermatology, 2014, Volume: 23, Issue:1 Topics: Animals; Autoimmune Diseases; Cytokines; Humans; Immunosuppressive Agents; Inflammation; Janus Kinases; Mice; Nitriles; Piperidines; Protein Kinase Inhibitors; Psoriasis; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction	2014
Therapeutic targeting of the Jak/STAT pathway. Basic & clinical pharmacology & toxicology, 2014, Volume: 114, Issue:1 Topics: Animals; Autoimmune Diseases; Cytokines; Disease Models, Animal; Humans; Janus Kinases; Nitriles; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; STAT Transcription Factors	2014
The biology of IL-15: implications for cancer therapy and the treatment of autoimmune disorders. The journal of investigative dermatology. Symposium proceedings, 2013, Volume: 16, Issue:1 Topics: Alopecia Areata; Animals; Antibodies, Monoclonal; Autoimmune Diseases; Humans; Interleukin-15; Leukemia-Lymphoma, Adult T-Cell; Neoplasms; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptors, Interleukin-15; Signal Transduction	2013
Janus kinases: an ideal target for the treatment of autoimmune diseases. The journal of investigative dermatology. Symposium proceedings, 2013, Volume: 16, Issue:1 Topics: Animals; Autoimmune Diseases; Cytokines; Humans; Janus Kinases; Nitriles; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Signal Transduction; STAT Transcription Factors	2013
Discovery and development of Janus kinase (JAK) inhibitors for inflammatory diseases. Journal of medicinal chemistry, 2014, Jun-26, Volume: 57, Issue:12 Topics: Animals; Anti-Inflammatory Agents; Antirheumatic Agents; Autoimmune Diseases; Clinical Trials as Topic; Cytokines; Humans; Inflammation; Inflammatory Bowel Diseases; Janus Kinases; Piperidines; Protein Conformation; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction	2014
Therapeutic potential of tyrosine kinase 2 in autoimmunity. Expert opinion on therapeutic targets, 2014, Volume: 18, Issue:5 Topics: Adaptive Immunity; Autoimmune Diseases; Autoimmunity; Dendritic Cells; Drug Design; Genetic Predisposition to Disease; Humans; Immunity, Cellular; Lymphocyte Subsets; Macrophages; Molecular Targeted Therapy; Neutrophils; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; TYK2 Kinase	2014
Therapeutic Potential of Targeting the Th17/Treg Axis in Autoimmune Disorders. Molecules (Basel, Switzerland), 2017, Jan-14, Volume: 22, Issue:1 Topics: Animals; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Autoimmune Diseases; Forkhead Transcription Factors; Gene Expression Regulation; Humans; Immunologic Factors; Inflammation; Interleukin-17; Nuclear Receptor Subfamily 1, Group F, Member 3; Piperidines; Pyrimidines; Pyrroles; Signal Transduction; T-Lymphocytes, Regulatory; Th17 Cells; Ustekinumab	2017
Treating inflammation with the Janus kinase inhibitor CP-690,550. Trends in pharmacological sciences, 2011, Volume: 32, Issue:1 Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Autoimmune Diseases; Graft Rejection; Humans; Immunosuppressive Agents; Inflammation; Isoenzymes; Janus Kinase 3; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Signal Transduction; STAT Transcription Factors	2011
Current landscape for T-cell targeting in autoimmunity and transplantation. Immunotherapy, 2011, Volume: 3, Issue:7 Topics: Autoimmune Diseases; Calcineurin Inhibitors; Cell Differentiation; Cell Proliferation; Cytokines; Hematopoietic Stem Cell Transplantation; Humans; Immunosuppression Therapy; Immunosuppressive Agents; Janus Kinase 3; Organ Transplantation; Piperidines; Protein Kinase C; Pyrimidines; Pyrroles; Quinazolines; Receptors, Cytokine; T-Lymphocytes; Transplantation Immunology; Transplantation Tolerance	2011
Emphysema: an autoimmune vascular disease? Proceedings of the American Thoracic Society, 2005, Volume: 2, Issue:1 Topics: Animals; Apoptosis; Autoantibodies; Autoimmune Diseases; Cell Proliferation; Endothelial Growth Factors; Glucocorticoids; Indoles; Methylprednisolone; Oxidative Stress; Protein Kinase Inhibitors; Pulmonary Emphysema; Pyrroles; Rats; Receptors, Vascular Endothelial Growth Factor	2005
Down-regulation of autoreactive T-cells by HMG CoA reductase inhibitors. Clinical immunology (Orlando, Fla.), 2006, Volume: 119, Issue:1 Topics: Animals; Antigen-Presenting Cells; Atorvastatin; Autoimmune Diseases; Cholesterol; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Down-Regulation; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Pyrroles; T-Lymphocytes	2006
[Immunointervention in newly diagnosed type 1 diabetes]. Deutsche medizinische Wochenschrift (1946), 2006, Dec-08, Volume: 131, Issue:49 Topics: Antibodies, Monoclonal; Atorvastatin; Autoimmune Diseases; Diabetes Mellitus, Type 1; Heptanoic Acids; Humans; Immunosuppressive Agents; Insulin-Secreting Cells; Prediabetic State; Pyrroles	2006

Trials

1 trial(s) available for pyrroles and Autoimmune Disease

Article	Year
An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis. The Journal of investigative dermatology, 2018, Volume: 138, Issue:7 Topics: Adult; Alopecia Areata; Autoimmune Diseases; Biopsy; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Hair Follicle; Humans; Janus Kinase Inhibitors; Janus Kinases; Male; Middle Aged; Nitriles; Photography; Pilot Projects; Piperidines; Pyrazoles; Pyrimidines; Pyrroles; Severity of Illness Index; Treatment Outcome; Young Adult	2018

Article

Year

An Open-Label Pilot Study to Evaluate the Efficacy of Tofacitinib in Moderate to Severe Patch-Type Alopecia Areata, Totalis, and Universalis.

The Journal of investigative dermatology, 2018, Volume: 138, Issue:7

Topics: Adult; Alopecia Areata; Autoimmune Diseases; Biopsy; Dose-Response Relationship, Drug; Female; Gene Expression Profiling; Hair Follicle; Humans; Janus Kinase Inhibitors; Janus Kinases; Male; Middle Aged; Nitriles; Photography; Pilot Projects; Piperidines; Pyrazoles; Pyrimidines; Pyrroles; Severity of Illness Index; Treatment Outcome; Young Adult

2018

Other Studies

23 other study(ies) available for pyrroles and Autoimmune Disease

Article	Year
PD-1 Targeted Nanoparticles Inhibit Activated T Cells and Alleviate Autoimmunity via Suppression of Cellular Energy Metabolism Mediated by PKM2. International journal of nanomedicine, 2022, Volume: 17 Topics: Animals; Autoimmune Diseases; Autoimmunity; Disease Models, Animal; Energy Metabolism; Mice; Mice, Inbred C57BL; Nanoparticles; Programmed Cell Death 1 Receptor; Pyridazines; Pyrroles; Pyruvate Kinase; Th1 Cells; Th17 Cells	2022
Treating Autoimmune Diseases by Targeting IL-23 with Gene-Silencing Pyrrole-Imidazole Polyamide. Journal of immunology (Baltimore, Md. : 1950), 2020, 04-15, Volume: 204, Issue:8 Topics: Animals; Autoimmune Diseases; Female; Gene Silencing; Imidazoles; Imiquimod; Interleukin-23 Subunit p19; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Structure; Nylons; Psoriasis; Pyrroles; Uveitis	2020
Commentary: Janus kinase inhibitors and their use in autoimmune ocular inflammatory disorders. Indian journal of ophthalmology, 2020, Volume: 68, Issue:9 Topics: Autoimmune Diseases; Humans; Janus Kinase Inhibitors; Piperidines; Pyrimidines; Pyrroles; Uveomeningoencephalitic Syndrome	2020
Identification of N-{cis-3-[Methyl(7H-pyrrolo[2,3-d]pyrimidin-4-yl)amino]cyclobutyl}propane-1-sulfonamide (PF-04965842): A Selective JAK1 Clinical Candidate for the Treatment of Autoimmune Diseases. Journal of medicinal chemistry, 2018, 02-08, Volume: 61, Issue:3 Topics: Animals; Arthritis, Experimental; Autoimmune Diseases; Cyclobutanes; Dogs; Drug Evaluation, Preclinical; Humans; Inhibitory Concentration 50; Janus Kinase 1; Janus Kinase 2; Models, Molecular; Protein Conformation; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rats; Substrate Specificity; Sulfonamides; Tissue Distribution	2018
High-throughput T cell receptor sequencing identifies clonally expanded CD8+ T cell populations in alopecia areata. JCI insight, 2018, 10-04, Volume: 3, Issue:19 Topics: Adolescent; Adult; Alopecia Areata; Animals; Autoimmune Diseases; CD8-Positive T-Lymphocytes; Disease Models, Animal; Female; Follow-Up Studies; Hair Follicle; High-Throughput Nucleotide Sequencing; Humans; Lymph Nodes; Male; Mice; Mice, Inbred C3H; Middle Aged; NK Cell Lectin-Like Receptor Subfamily K; Pilot Projects; Piperidines; Pyrimidines; Pyrroles; Receptors, Antigen, T-Cell; Scalp; Treatment Outcome; Young Adult	2018
Disorders of Hypopigmentation Journal of drugs in dermatology : JDD, 2019, Mar-01, Volume: 18, Issue:3 Topics: Administration, Cutaneous; Administration, Oral; Autoimmune Diseases; CD8-Positive T-Lymphocytes; Counseling; Dermatologic Agents; Diagnosis, Differential; Epidermis; Humans; Janus Kinases; Melanocytes; Mycosis Fungoides; Nitriles; Phototherapy; Piperidines; Protein Kinase Inhibitors; Pyrazoles; Pyrimidines; Pyrroles; Quality of Life; Skin Pigmentation; Tinea Versicolor; Vitiligo	2019
Update in rheumatology: evidence published in 2012. Annals of internal medicine, 2013, Jun-18, Volume: 158, Issue:12 Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Antibodies, Monoclonal, Humanized; Antibodies, Monoclonal, Murine-Derived; Antirheumatic Agents; Antiviral Agents; Arthritis; Arthritis, Gouty; Arthritis, Rheumatoid; Autoimmune Diseases; Bacterial Infections; Calcitonin; Colchicine; Cryoglobulinemia; Death, Sudden, Cardiac; Drug Resistance, Viral; Enzyme Inhibitors; Female; Gout; Gout Suppressants; Hand Joints; Hepatitis C, Chronic; Humans; Hyperuricemia; Immunologic Factors; Janus Kinase 3; Male; Myocardial Infarction; Neoplasms; Osteoarthritis; Osteoarthritis, Hip; Osteoarthritis, Knee; Practice Guidelines as Topic; Protein Precursors; Pyrimidines; Pyrroles; Registries; Tumor Necrosis Factor-alpha	2013
Persisting weakness after withdrawal of a statin. BMJ case reports, 2014, Apr-08, Volume: 2014 Topics: Aged, 80 and over; Atorvastatin; Autoimmune Diseases; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscle Weakness; Myositis; Necrosis; Pyrroles	2014
Evaluation of JAK3 Biology in Autoimmune Disease Using a Highly Selective, Irreversible JAK3 Inhibitor. The Journal of pharmacology and experimental therapeutics, 2017, Volume: 361, Issue:2 Topics: Animals; Arthritis, Experimental; Autoimmune Diseases; Dose-Response Relationship, Drug; Drug Monitoring; Humans; Isoenzymes; Janus Kinase 1; Janus Kinase 3; Monitoring, Immunologic; Piperidines; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Rats	2017
Comment and reply on: Atorvastatin: safety and tolerability. Statins and polymyositis: a neglected link? Expert opinion on drug safety, 2010, Volume: 9, Issue:6 Topics: Atorvastatin; Autoimmune Diseases; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Muscular Diseases; Polymyositis; Pyrroles	2010
Discovery of CP-690,550: a potent and selective Janus kinase (JAK) inhibitor for the treatment of autoimmune diseases and organ transplant rejection. Journal of medicinal chemistry, 2010, Dec-23, Volume: 53, Issue:24 Topics: Animals; Autoimmune Diseases; Blood Proteins; Caco-2 Cells; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Cyclohexane Monoterpenes; Dogs; Female; Fibroblasts; Graft Rejection; Humans; In Vitro Techniques; Janus Kinases; Lymphocyte Activation; Macaca fascicularis; Male; Models, Molecular; Monoterpenes; Piperidines; Protein Binding; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Stereoisomerism; Structure-Activity Relationship; T-Lymphocytes; Tissue Distribution	2010
EC144, a synthetic inhibitor of heat shock protein 90, blocks innate and adaptive immune responses in models of inflammation and autoimmunity. Journal of immunology (Baltimore, Md. : 1950), 2011, Jan-01, Volume: 186, Issue:1 Topics: Adaptive Immunity; Animals; Autoimmune Diseases; Cell Line; Cell Line, Transformed; Crystallography, X-Ray; Disease Models, Animal; Female; HSP90 Heat-Shock Proteins; Humans; Immunity, Innate; Immunosuppressive Agents; Inflammation; Inflammation Mediators; Mice; Mice, Inbred BALB C; Mice, Inbred DBA; Pyrimidines; Pyrroles; Rats	2011
Autoimmune hepatitis revealed by atorvastatin. European journal of gastroenterology & hepatology, 2003, Volume: 15, Issue:8 Topics: Aged; Alanine Transaminase; Aspartate Aminotransferases; Atorvastatin; Autoimmune Diseases; Bilirubin; Chemical and Drug Induced Liver Injury; Female; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Liver; Liver Function Tests; Pyrroles	2003
Toward a role for statins in immunomodulation. Molecular interventions, 2002, Volume: 2, Issue:8 Topics: Adjuvants, Immunologic; Animals; Atorvastatin; Autoimmune Diseases; Cytokines; Drug Therapy, Combination; Fatty Acids, Monounsaturated; Fluvastatin; Genes, MHC Class II; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Immunosuppressive Agents; Indoles; Lovastatin; Mice; Pravastatin; Pyrroles; Simvastatin	2002
Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction. Journal of immunology (Baltimore, Md. : 1950), 2005, Feb-15, Volume: 174, Issue:4 Topics: Administration, Oral; Animals; Atorvastatin; Autoimmune Diseases; Cell Line; Cell Migration Inhibition; Cell Proliferation; Cytokines; Female; Growth Inhibitors; Heptanoic Acids; Humans; Immunosuppressive Agents; Injections, Intraperitoneal; Lovastatin; Male; Mice; Mice, Inbred C57BL; Pyrroles; Rats; Rats, Inbred Lew; Retinitis; Th2 Cells; Uveitis	2005
The effects of atorvastatin in experimental autoimmune uveitis. The British journal of ophthalmology, 2005, Volume: 89, Issue:3 Topics: Animals; Atorvastatin; Autoimmune Diseases; Blotting, Western; DNA-Binding Proteins; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interleukin-1; Interleukin-2; Mice; Mice, Inbred Strains; Models, Animal; Pyrroles; STAT4 Transcription Factor; STAT6 Transcription Factor; Th1 Cells; Th2 Cells; Trans-Activators; Tumor Necrosis Factor-alpha; Uveitis	2005
Rosuvastatin-associated hepatitis with autoimmune features. European journal of gastroenterology & hepatology, 2005, Volume: 17, Issue:5 Topics: Anticholesteremic Agents; Atorvastatin; Autoimmune Diseases; Chemical and Drug Induced Liver Injury; Female; Heptanoic Acids; Humans; Middle Aged; Pyrroles	2005
Effects of atorvastatin on the Th1/Th2 polarization of ongoing experimental autoimmune myocarditis in Lewis rats. Journal of autoimmunity, 2005, Volume: 25, Issue:4 Topics: Animals; Atorvastatin; Autoimmune Diseases; Cholesterol; Cytokines; Genetic Predisposition to Disease; Heart Function Tests; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocarditis; Myocardium; Pyrroles; Rats; Rats, Inbred Lew; Th1 Cells; Th2 Cells	2005
Immunoregulatory effects of atorvastatin on experimental autoimmune myocarditis in Lewis rats. Immunology and cell biology, 2006, Volume: 84, Issue:3 Topics: Adoptive Transfer; Animals; Atorvastatin; Autoimmune Diseases; Disease Models, Animal; Echocardiography; Enzyme-Linked Immunosorbent Assay; Genes, MHC Class II; Heptanoic Acids; Histocompatibility Antigens Class II; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Myocarditis; Myocardium; Myocytes, Cardiac; Nuclear Proteins; Polymerase Chain Reaction; Pyrroles; Rats; Rats, Inbred Lew; RNA, Messenger; T-Lymphocytes; Th2 Cells; Trans-Activators	2006
Development of new pyrrolopyrimidine-based inhibitors of Janus kinase 3 (JAK3). Bioorganic & medicinal chemistry letters, 2007, Mar-01, Volume: 17, Issue:5 Topics: Autoimmune Diseases; Cell Line, Tumor; Cell Proliferation; Humans; Immunity; Janus Kinase 2; Janus Kinase 3; Pyrimidines; Pyrroles; Structure-Activity Relationship	2007
Treatment of experimental autoimmune uveoretinitis with atorvastatin and lovastatin. Experimental eye research, 2007, Volume: 84, Issue:3 Topics: Administration, Oral; Animals; Arrestin; Atorvastatin; Autoimmune Diseases; Cattle; Cell Proliferation; Cytokines; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypersensitivity, Delayed; Immunohistochemistry; Injections, Intraperitoneal; Lovastatin; Lymph Nodes; Macrophages; Models, Animal; Pyrroles; Rats; Rats, Inbred Lew; Retina; Retinitis; T-Lymphocytes; Uvea; Uveitis	2007
Antiarrhythmic effect of atorvastatin on autoimmune myocarditis is mediated by improving myocardial repolarization. Life sciences, 2007, Jan-23, Volume: 80, Issue:7 Topics: Action Potentials; Animals; Arrhythmias, Cardiac; Atorvastatin; Autoimmune Diseases; Disease Models, Animal; Heart; Heart Ventricles; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Interferon-gamma; Mice; Mice, Inbred BALB C; Myocarditis; Myocardium; Myocytes, Cardiac; Patch-Clamp Techniques; Potassium Channels; Pyrroles; Tumor Necrosis Factor-alpha; Ventricular Function	2007
Atorvastatin-induced reversible positive antinuclear antibodies. The American journal of medicine, 2002, Volume: 112, Issue:4 Topics: Adult; Antibodies, Antinuclear; Atorvastatin; Autoimmune Diseases; Heptanoic Acids; Histones; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Lupus Erythematosus, Systemic; Male; Pyrroles	2002