pyrroles has been researched along with Allodynia in 38 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (5.26) | 18.2507 |
| 2000's | 12 (31.58) | 29.6817 |
| 2010's | 22 (57.89) | 24.3611 |
| 2020's | 2 (5.26) | 2.80 |
| Authors | Studies |
|---|---|
| Banerjee, P; Behravesh, S; Dodick, DW; Navratilova, E; Oyarzo, J; Porreca, F | 1 |
| Ding, X; Fan, X; Han, J; Ning, L; Tang, S; Wang, C | 1 |
| Butt, RP; Dua, P; Gore, K; Gorman, D; Groeneveld, GJ; Hay, JL; Loudon, P; Siebenga, P; van Amerongen, G | 1 |
| Leánez, S; Pol, O; Redondo, A; Riego, G | 1 |
| Alves, VS; Costa, R; Dias, FC; Figueiredo, CP; Matias, DO; Miranda, ALP; Passos, GF | 1 |
| Choi, HY; Jang, C; Lee, JY; Lee, KT; Park, CS; Youn, I; Yune, TY | 1 |
| Bowen, CA; Fang, X; Heffernan, ML; Hopkins, SC; Large, TH; Spanswick, DC; Spear, KL; Varney, MA; Wei, H; Zhao, FY | 1 |
| Antunes, F; Barreiro, EJ; Fraga, CA; Mendes, TC; Nascimento, NM; Sudo, RT; Trachez, MM; Zapata-Sudo, G | 1 |
| Bonanno, G; Di Cesare Mannelli, L; Fariello, RG; Farina, C; Ghelardini, C; Milanese, M; Misiano, P; Pittaluga, A | 1 |
| Balaganur, V; Kant, V; Kumar, D; Latief, N; Lingaraju, MC; More, AS; Pathak, NN; Tandan, SK | 1 |
| Aoki, Y; Mizoguchi, H; Sakurada, S; Sakurada, T; Takeda, K; Watanabe, C | 1 |
| Abogadie, FC; Bunnett, NW; Darby, B; Grace, MS; Lieu, T; McIntyre, P; Veldhuis, N | 1 |
| Di Cesare Mannelli, L; Farina, C; Ghelardini, C; Maresca, M; Scherz, MW | 1 |
| Carcolé, M; Castany, S; Leánez, S; Pol, O | 1 |
| Anzini, M; Biava, M; Brindisi, M; Brogi, S; Cappelli, A; Di Capua, A; Di Cesare Mannelli, L; Ghelardini, C; Giordani, A; Giorgi, G; Pace, S; Poce, G; Rossi, A; Sautebin, L; Sticozzi, C; Valacchi, G | 1 |
| Crestani, F; Knabl, J; Rudolph, U; Zeilhofer, HU; Zeilhofer, UB | 1 |
| Almqvist, PM; Finnerup, NB; Gormsen, L; Jensen, TS | 1 |
| Barreiro, EJ; Fraga, CA; Mendes, TC; Nascimento-Junior, NM; Raimundo, JM; Sudo, RT; Zapata-Sudo, G | 1 |
| Kumar, VL; Wahane, VD | 1 |
| Cummons, T; Harrison, JE; Hummel, M; Kennedy, JD; Lu, P; Mark, L; Whiteside, GT | 1 |
| Guruprasad, B; Kumar, VL; Wahane, VD | 1 |
| Chen, Y; Wang, ZJ; Yang, C | 1 |
| Alfonso, S; Anzellotti, P; Anzini, M; Battilocchio, C; Biava, M; Bruno, A; Calderone, V; Di Cesare Mannelli, L; Ghelardini, C; Giordani, A; Giorgi, G; Martelli, A; Papa, G; Patrignani, P; Poce, G; Porretta, GC; Rossi, A; Rovini, M; Sautebin, L; Testai, L; Valenti, S | 1 |
| Benemei, S; Creminon, C; Fusi, C; Geppetti, P; Materazzi, S; Nassini, R; Nilius, B; Patacchini, R; Pedretti, P; Prenen, J | 1 |
| Borrelli, G; Borsini, F; Brindisi, M; Butini, S; Cabri, W; Campiani, G; Caprioli, A; Di Serio, S; Fezza, F; Gallo, G; Gemma, S; Maccarrone, M; Maramai, S; Minetti, P; Ros, S; Stasi, MA; Talamonti, E; Vincenti, S | 1 |
| Dulin, JN; Grill, RJ; Karoly, ED; Strobel, HW; Wang, Y | 1 |
| Aoki, K; Kimura, T; Nakajima-Yamada, T; Shimozato, T; Tsuchida, J; Ushiyama, S; Wada, Y; Yamada, K; Yasumoto, T | 1 |
| Barsante, MM; Castro, MS; Pinho, V; Roffê, E; Souza, DG; Tafuri, WL; Teixeira, MM; Yokoro, CM | 1 |
| Abe, T; Imagawa, N; Ito, M; Matsushita, M; Sagawa, S; Sakoda, K; Sasase, T; Tanaka, M; Yamada, H | 1 |
| Kulkarni, SK; Patil, CS; Singh, VP | 1 |
| Cunha, FQ; Cunha, TM; Ferreira, SH; Parada, CA; Poole, S; Santodomingo-Garzón, T; Valério, DA; Verri, WA | 1 |
| Martinez, V; Taché, Y | 1 |
| Miranda, A; Nordstrom, E; Sengupta, JN; Smith, C | 1 |
| Ahmadiani, A; Esmaeili-Mahani, S; Javan, M; Koibuchi, N; Maghsoudi, N; Motamedi, F; Shimokawa, N | 1 |
| Bradesi, S; Larauche, M; Mayer, EA; McLean, P; McRoberts, JA; Million, M; Taché, Y | 1 |
| Arban, R; Belardetti, F; Bettelini, L; Carignani, C; Corsi, M; Dal Forno, G; Di Fabio, R; Maraia, G; Mugnaini, M; Quartaroli, M; Ratti, E; Reggiani, A; Trist, DG; Ugolini, A | 1 |
| Kamei, J; Ohsawa, M | 1 |
1 review(s) available for pyrroles and Allodynia
| Article | Year |
|---|---|
CRF1 receptors as a therapeutic target for irritable bowel syndrome.
Topics: Animals; Brain; Corticotropin-Releasing Hormone; Gastrointestinal Motility; Gastrointestinal Tract; Hormone Antagonists; Humans; Hyperalgesia; Intestinal Mucosa; Irritable Bowel Syndrome; Peptide Fragments; Pyrimidines; Pyrroles; Receptors, Corticotropin-Releasing Hormone; Stress, Psychological; Urocortins | 2006 |
2 trial(s) available for pyrroles and Allodynia
| Article | Year |
|---|---|
Demonstration of an anti-hyperalgesic effect of a novel pan-Trk inhibitor PF-06273340 in a battery of human evoked pain models.
Topics: Adolescent; Adult; Analgesics; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Healthy Volunteers; Humans; Hyperalgesia; Male; Membrane Glycoproteins; Middle Aged; Pain Threshold; Pyrimidines; Pyrroles; Receptor, trkA; Receptor, trkB; Receptor, trkC; Young Adult | 2018 |
The efficacy of the AMPA receptor antagonist NS1209 and lidocaine in nerve injury pain: a randomized, double-blind, placebo-controlled, three-way crossover study.
Topics: Adult; Aged; Analgesia; Anesthetics, Local; Chronic Disease; Cross-Over Studies; Double-Blind Method; Excitatory Amino Acid Antagonists; Female; Humans; Hyperalgesia; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Peripheral Nerves; Peripheral Nervous System Diseases; Pyrroles; Receptors, AMPA; Receptors, Kainic Acid; Tetrahydroisoquinolines; Time Factors; Treatment Outcome; Young Adult | 2009 |
35 other study(ies) available for pyrroles and Allodynia
| Article | Year |
|---|---|
Ubrogepant does not induce latent sensitization in a preclinical model of medication overuse headache.
Topics: Analgesics; Animals; Central Nervous System Sensitization; Disease Models, Animal; Female; Headache Disorders, Secondary; Hyperalgesia; Pyridines; Pyrroles; Rats; Rats, Sprague-Dawley; Sumatriptan | 2020 |
Role of TRPV4-P2X7 Pathway in Neuropathic Pain in Rats with Chronic Compression of the Dorsal Root Ganglion.
Topics: Animals; Ganglia, Spinal; Hyperalgesia; Leucine; Male; Morpholines; Nerve Compression Syndromes; Neuralgia; Purinergic P2X Receptor Antagonists; Pyrroles; Rats, Wistar; Receptors, Purinergic P2X7; Rosaniline Dyes; Signal Transduction; Sulfonamides; TRPV Cation Channels | 2021 |
Mechanism implicated in the anti-allodynic and anti-hyperalgesic effects induced by the activation of heme oxygenase 1/carbon monoxide signaling pathway in the central nervous system of mice with neuropathic pain.
Topics: Animals; Carbon Monoxide; Central Nervous System; Gene Expression Regulation; Heme Oxygenase-1; Hyperalgesia; Male; Mice; Mice, Inbred C57BL; Neuralgia; Organometallic Compounds; Pyrazines; Pyrroles; Sciatic Nerve; Signal Transduction | 2018 |
The selective TRPV4 channel antagonist HC-067047 attenuates mechanical allodynia in diabetic mice.
Topics: Animals; Body Temperature; Body Weight; Diabetic Neuropathies; Ganglia, Spinal; Gene Expression Regulation; Hyperalgesia; Locomotion; Male; Mice; Morpholines; Psychomotor Performance; Pyrroles; Sciatic Nerve; TRPV Cation Channels | 2019 |
Inhibition of COX-2 alleviates lumbar spinal stenosis-induced chronic mechanical allodynia in rats.
Topics: Animals; Cauda Equina; Celecoxib; Chronic Pain; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cytokines; Dinoprostone; Hyperalgesia; Lumbar Vertebrae; Macrophages; Male; Neuralgia; Pyrroles; Rats, Sprague-Dawley; Spinal Stenosis | 2019 |
Pharmacodynamic effects of a D-amino acid oxidase inhibitor indicate a spinal site of action in rat models of neuropathic pain.
Topics: Amines; Analgesics; Anesthesia; Animals; Behavior, Animal; Constriction, Pathologic; Cyclohexanecarboxylic Acids; D-Amino-Acid Oxidase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Freund's Adjuvant; Furans; Gabapentin; gamma-Aminobutyric Acid; Hot Temperature; Hyperalgesia; Ligation; Male; Neuralgia; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Serine; Spinal Cord; Spinal Nerves | 2013 |
Antihyperalgesic effects of a novel muscarinic agonist (LASSBio-873) in spinal nerve ligation in rats.
Topics: Analgesics; Animals; Hyperalgesia; Male; Muscarinic Agonists; Neuralgia; Pain Measurement; Peripheral Nerve Injuries; Pyrazoles; Pyridines; Pyrroles; Rats; Rats, Wistar; Receptor, Muscarinic M2; Spinal Nerves | 2013 |
Broad spectrum and prolonged efficacy of dimiracetam in models of neuropathic pain.
Topics: Analysis of Variance; Animals; Anti-Retroviral Agents; Antineoplastic Agents, Phytogenic; Disease Models, Animal; Hyperalgesia; Imidazoles; Male; Neuralgia; Osteoarthritis, Knee; Paclitaxel; Pain Measurement; Pain Threshold; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate; Vincristine; Weight-Bearing | 2014 |
Atorvastatin attenuates neuropathic pain in rat neuropathy model by down-regulating oxidative damage at peripheral, spinal and supraspinal levels.
Topics: Animals; Antioxidants; Atorvastatin; Down-Regulation; Heptanoic Acids; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperalgesia; Male; Neuralgia; Oxidative Stress; Pyrroles; Rats, Wistar; Sciatic Nerve; Spinal Cord | 2014 |
Potential involvement of μ-opioid receptor dysregulation on the reduced antinociception of morphine in the inflammatory pain state in mice.
Topics: Analgesics, Opioid; Animals; Disease Models, Animal; Freund's Adjuvant; Ganglia, Spinal; Hyperalgesia; Indoles; Inflammation; Injections, Subcutaneous; Male; Mice; Mice, Inbred Strains; Morphine; Pain; Phosphorylation; Protein Kinase C-alpha; Pyrroles; Receptors, Opioid, mu; Spinal Cord | 2014 |
The tyrosine kinase inhibitor bafetinib inhibits PAR2-induced activation of TRPV4 channels in vitro and pain in vivo.
Topics: Animals; HEK293 Cells; Humans; Hyperalgesia; Leucine; Male; Mice, Inbred C57BL; Morpholines; Oligopeptides; Pain; Protein Kinase Inhibitors; Pyrimidines; Pyrroles; Receptor, PAR-2; Sulfonamides; TRPV Cation Channels; Trypsin | 2014 |
A model of neuropathic pain induced by sorafenib in the rat: Effect of dimiracetam.
Topics: Analgesics; Analysis of Variance; Animals; Antineoplastic Agents; Disease Models, Animal; Dose-Response Relationship, Drug; Hyperalgesia; Imidazoles; Male; Neuralgia; Niacinamide; Pain Measurement; Pain Threshold; Phenylurea Compounds; Pyrroles; Rats; Rats, Sprague-Dawley; Reaction Time; Sorafenib; Time Factors | 2015 |
The antinociceptive effects of a δ-opioid receptor agonist in mice with painful diabetic neuropathy: Involvement of heme oxygenase 1.
Topics: Analgesics, Opioid; Animals; Diabetic Neuropathies; Dose-Response Relationship, Drug; Enkephalin, D-Penicillamine (2,5)-; Enzyme Induction; Heme Oxygenase-1; Hyperalgesia; Injections, Subcutaneous; Male; Mice, Inbred C57BL; Organometallic Compounds; Physical Stimulation; Pyrazines; Pyrroles; Receptors, Opioid, delta; Ruthenium | 2016 |
Synthesis and biological evaluation of fluorinated 1,5-diarylpyrrole-3-alkoxyethyl ether derivatives as selective COX-2 inhibitors endowed with anti-inflammatory activity.
Topics: Adult; Analgesics; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antineoplastic Agents; Cell Line; Cell Proliferation; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Edema; Halogenation; Humans; Hyperalgesia; Models, Molecular; Pyrroles; Rats; Skin; Skin Neoplasms | 2016 |
The role of spinal thrombin through protease-activated receptor 1 in hyperalgesia after neural injury.
Topics: Animals; Antithrombins; Capillary Permeability; Central Nervous System Agents; Cervical Vertebrae; Disease Models, Animal; Fibrin; Hirudins; Hyperalgesia; Injections, Spinal; Male; Pain; Pain Measurement; Peripheral Nervous System Diseases; Pyrroles; Quinazolines; Radiculopathy; Rats, Sprague-Dawley; Receptor, PAR-1; Spinal Cord | 2017 |
Genuine antihyperalgesia by systemic diazepam revealed by experiments in GABAA receptor point-mutated mice.
Topics: Analysis of Variance; Anesthetics; Animals; Arginine; Diazepam; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Formaldehyde; Histidine; Hyperalgesia; Indoles; Male; Mice; Mice, Mutant Strains; Motor Activity; Physical Stimulation; Point Mutation; Protein Subunits; Pyrroles; Receptors, GABA-A | 2009 |
Sedation and antinociception induced by a new pyrazolo[3,4-b]pyrrolo[3,4-d]pyridine derivative (LASSBio-873) is modulated by activation of muscarinic receptors.
Topics: Adrenergic alpha-Antagonists; Analgesics; Analysis of Variance; Animals; Behavior, Animal; Dose-Response Relationship, Drug; Exploratory Behavior; GABA Antagonists; Hot Temperature; Hyperalgesia; Hypnotics and Sedatives; Inflammation; Male; Mice; Motor Activity; Muscarinic Antagonists; Narcotic Antagonists; Pain; Pain Measurement; Pyrazoles; Pyridines; Pyrroles; Receptors, Muscarinic | 2009 |
Atorvastatin ameliorates inflammatory hyperalgesia in rat model of monoarticular arthritis.
Topics: Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Atorvastatin; Diclofenac; Female; Freund's Adjuvant; Heptanoic Acids; Hyperalgesia; Inflammation; Joints; Lower Extremity; Male; Motor Activity; Pyrroles; Rats; Rats, Wistar | 2010 |
Pain is a salient "stressor" that is mediated by corticotropin-releasing factor-1 receptors.
Topics: Aniline Compounds; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Corticotropin-Releasing Hormone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Hyperalgesia; Indomethacin; Inflammation; Male; Mice; Pain; Pain Threshold; Pyrimidines; Pyrroles; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Spinal Cord Injuries; Stomach Ulcer; Stress, Psychological | 2010 |
Atorvastatin exhibits anti-inflammatory and anti-oxidant properties in adjuvant-induced monoarthritis.
Topics: Animals; Anti-Inflammatory Agents; Antioxidants; Arthritis, Experimental; Atorvastatin; Dose-Response Relationship, Drug; Female; Freund's Adjuvant; Glutathione; Heptanoic Acids; Hyperalgesia; Injections, Intra-Articular; Joints; Male; Oxidative Stress; Pyrroles; Rats; Rats, Wistar; Superoxide Dismutase; Thiobarbituric Acid Reactive Substances | 2010 |
Proteinase-activated receptor 2 sensitizes transient receptor potential vanilloid 1, transient receptor potential vanilloid 4, and transient receptor potential ankyrin 1 in paclitaxel-induced neuropathic pain.
Topics: Analysis of Variance; Anilides; Animals; Ankyrins; Antineoplastic Agents, Phytogenic; Capsaicin; Carbazoles; Central Nervous System; Cinnamates; Cyclic AMP-Dependent Protein Kinases; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Estrenes; Gene Expression Regulation; Hyperalgesia; Male; Mice; Mice, Inbred ICR; Neuralgia; Oligopeptides; Paclitaxel; Pain Measurement; Physical Stimulation; Protein Kinase C; Pyrroles; Pyrrolidinones; Receptor, PAR-2; Sulfonamides; Time Factors; TRPV Cation Channels; Tryptases; Type C Phospholipases | 2011 |
Novel analgesic/anti-inflammatory agents: diarylpyrrole acetic esters endowed with nitric oxide releasing properties.
Topics: Acetates; Animals; Cell Line; Constriction, Pathologic; Cyclooxygenase 2 Inhibitors; Edema; Esters; Humans; Hyperalgesia; In Vitro Techniques; Isoenzymes; Macrophages; Male; Mice; Models, Molecular; Nitric Oxide Donors; Pyrroles; Rats; Rats, Sprague-Dawley; Rats, Wistar; Structure-Activity Relationship; Vasodilator Agents | 2011 |
TRPA1 and TRPV4 mediate paclitaxel-induced peripheral neuropathy in mice via a glutathione-sensitive mechanism.
Topics: Acetanilides; Animals; Calcitonin Gene-Related Peptide; Capsaicin; Cold Temperature; Drug Hypersensitivity; Glutathione; Hyperalgesia; In Vitro Techniques; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Morpholines; Paclitaxel; Peripheral Nervous System Diseases; Purines; Pyrroles; Transient Receptor Potential Channels; TRPA1 Cation Channel; TRPV Cation Channels | 2012 |
Discovery of potent inhibitors of human and mouse fatty acid amide hydrolases.
Topics: Amidohydrolases; Analgesics; Animals; Brain; CHO Cells; Cricetinae; Cricetulus; Cyclohexanes; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Furans; Humans; Hyperalgesia; Maze Learning; Mice; Models, Molecular; Pain Threshold; Pyrroles; Rats; Recombinant Proteins; Stereotyped Behavior; Structure-Activity Relationship; Thiophenes | 2012 |
Licofelone modulates neuroinflammation and attenuates mechanical hypersensitivity in the chronic phase of spinal cord injury.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chromatography, High Pressure Liquid; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme-Linked Immunosorbent Assay; Female; Gas Chromatography-Mass Spectrometry; Hindlimb; Hot Temperature; Hyperalgesia; Inflammation; Leukotriene B4; Locomotion; Metabolomics; Oxidative Stress; Physical Stimulation; Pyrroles; Rats; Rats, Sprague-Dawley; Spinal Cord Injuries | 2013 |
R-130823, a novel inhibitor of p38 MAPK, ameliorates hyperalgesia and swelling in arthritis models.
Topics: Animals; Arthritis, Experimental; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Hyperalgesia; Male; Mice; Mice, Inbred DBA; p38 Mitogen-Activated Protein Kinases; Pyridines; Pyrroles; Rats; Rats, Inbred Lew | 2005 |
Anti-inflammatory and analgesic effects of atorvastatin in a rat model of adjuvant-induced arthritis.
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Arthritis, Experimental; Atorvastatin; Chemokine CCL2; Chemokine CCL5; Chemokines, CC; Dose-Response Relationship, Drug; Edema; Female; Heptanoic Acids; Hindlimb; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperalgesia; Interleukin-1; Interleukin-10; Interleukin-6; Leukocytes; Neutrophils; Peroxidase; Pyrroles; Rats; Tarsal Joints; Time Factors; Tumor Necrosis Factor-alpha | 2005 |
Novel protein kinase C-beta isoform selective inhibitor JTT-010 ameliorates both hyper- and hypoalgesia in streptozotocin- induced diabetic rats.
Topics: Animals; Diabetes Mellitus, Experimental; Diabetic Neuropathies; Hyperalgesia; Hypesthesia; Indans; Male; Neural Conduction; Protein Kinase C; Protein Kinase C beta; Pyrroles; Rats; Rats, Sprague-Dawley; Sciatic Nerve | 2005 |
Anti-inflammatory effect of licofelone against various inflammatory challenges.
Topics: Acetates; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Edema; Female; Freund's Adjuvant; Granuloma; Hyperalgesia; Indomethacin; Lipoxygenase Inhibitors; Mice; Pain Measurement; Pain Threshold; Pyrroles; Rats; Rats, Wistar; Time Factors; Touch | 2006 |
Atorvastatin inhibits inflammatory hypernociception.
Topics: Animals; Atorvastatin; Bradykinin; Cholesterol; Cytokines; Dinoprostone; Enzyme Inhibitors; Heptanoic Acids; Hydroxymethylglutaryl CoA Reductases; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperalgesia; Inflammation; Interleukin-1; Lipopolysaccharides; Male; Mice; Nitric Oxide Synthase; Pain Measurement; Pyrroles; Skin | 2006 |
Neonatal gastric suctioning results in chronic visceral and somatic hyperalgesia: role of corticotropin releasing factor.
Topics: Abdominal Pain; Animals; Animals, Newborn; Catheterization; Chronic Disease; Corticotropin-Releasing Hormone; Gastric Mucosa; Hot Temperature; Hyperalgesia; Intubation, Gastrointestinal; Male; Manometry; Nociceptors; Pyrimidines; Pyrroles; Rats; Rats, Long-Evans; Receptors, Corticotropin-Releasing Hormone; Suction | 2007 |
Low-dose morphine induces hyperalgesia through activation of G alphas, protein kinase C, and L-type Ca 2+ channels in rats.
Topics: Alkaloids; Analgesics, Opioid; Animals; Benzophenanthridines; Calcium Channel Blockers; Calcium Channels, L-Type; Carbazoles; Cyclic AMP; Dose-Response Relationship, Drug; Gene Expression; GTP-Binding Proteins; Hyperalgesia; Immunoblotting; Indoles; Male; Morphine; Nifedipine; Polymerase Chain Reaction; Protein Kinase C; Protein Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; RNA, Messenger; Spinal Cord | 2008 |
Corticotropin-releasing factor type 1 receptors mediate the visceral hyperalgesia induced by repeated psychological stress in rats.
Topics: Animals; Blood-Brain Barrier; Chronic Disease; Colon; Corticotropin-Releasing Hormone; Disease Models, Animal; Hyperalgesia; Infusion Pumps, Implantable; Injections, Subcutaneous; Male; Mechanotransduction, Cellular; Peptide Fragments; Pressure; Pyrimidines; Pyrroles; Rats; Rats, Wistar; Receptors, Corticotropin-Releasing Hormone; Rectum; Stress, Psychological | 2008 |
Potent antihyperalgesic activity without tolerance produced by glycine site antagonist of N-methyl-D-aspartate receptor GV196771A.
Topics: Analgesics, Non-Narcotic; Animals; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Drug Tolerance; Electrophysiology; Embryo, Mammalian; Excitatory Amino Acid Antagonists; Hyperalgesia; In Vitro Techniques; Indoles; Male; Mice; Pain Measurement; Patch-Clamp Techniques; Pyrroles; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Glycine; Receptors, N-Methyl-D-Aspartate; Spinal Cord | 1999 |
Possible involvement of spinal protein kinase C in thermal allodynia and hyperalgesia in diabetic mice.
Topics: Analysis of Variance; Animals; Capsaicin; Carbazoles; Carcinogens; Cyclic AMP-Dependent Protein Kinases; Diabetes Mellitus; Enzyme Inhibitors; Hot Temperature; Hyperalgesia; Indoles; Male; Mice; Mice, Inbred ICR; Naphthalenes; Pain; Pain Measurement; Phorbol 12,13-Dibutyrate; Protein Kinase C; Pyrroles; Spinal Cord | 1999 |