pyrroles has been researched along with Acute Lymphoid Leukemia in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Barrett, JS; Borden, KLB; Carroll, AJ; Carroll, MP; Chen, IL; Culjkovic-Kraljacic, B; Davenport, JW; Devidas, M; Dreyer, ZE; Felix, CA; Harvey, RC; Heerema, NA; Hilden, JM; Hunger, SP; Jin, S; Moore, JS; Porazzi, P; Robinson, BW; Seif, AE; Tasian, SK; Teachey, DT; Urtishak, KA; Vincent, TL; Wang, LS; Willman, CL | 1 |
| Dai, L; Li, Y; Liu, S; Liu, X; Luo, X; Que, F; Xu, Y; Yu, L; Zhou, D; Zhu, Y | 1 |
| Butini, S; Campiani, G; Greene, LM; Nathwani, SM; Samali, A; Szegezdi, E; Williams, DC; Zisterer, DM | 1 |
| Bonapace, L; Bornhauser, BC; Bourquin, JP; Cario, G; Niggli, FK; Schäfer, BW; Schmitz, M; Schrappe, M; Stanulla, M; Ziegler, U | 1 |
| Bornhauser, B; Bourquin, JP | 1 |
| Harada, H; Heidari, N; Hicks, MA | 1 |
| Browne, PV; Campiani, G; Lawler, MP; Lysaght, J; Maginn, EN; McElligott, AM; Ryan, JM; Verma, NK; Williams, DC; Zisterer, DM | 1 |
| Atlas, SR; Bantly, AD; Barrett, JS; Cao, K; Carroll, AJ; Chen, IM; Cory, L; Devidas, M; Dreyer, ZE; Edwards, AY; Felix, CA; Heerema, NA; Hilden, JM; Hudome, A; Hunger, SP; Kundu, M; Moore, JS; Reaman, GH; Robinson, BW; Urtishak, KA; Wang, LS; Willman, CL; Yu, QC | 1 |
| Grosicka, A; Grosicki, S; Hołowiecki, J | 1 |
| Thomas, X | 1 |
| Dimitroulakos, J; Minden, MD; Penn, LZ; Tan, MM; Wong, WW; Xia, Z | 1 |
2 review(s) available for pyrroles and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
[Clinical importance of angiogenesis and angiogenic factors in oncohematology].
Topics: Angiogenesis Inducing Agents; Angiogenesis Inhibitors; Angiopoietin-1; Angiopoietin-2; Hematologic Neoplasms; Humans; Indoles; Leukemia, Lymphocytic, Chronic, B-Cell; Leukemia, Myeloid, Acute; Multiple Myeloma; Myelodysplastic Syndromes; Neoplasm Metastasis; Neovascularization, Pathologic; Oxindoles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Propionates; Pyrroles; Receptor, TIE-2; Receptors, Vascular Endothelial Growth Factor; Vascular Endothelial Growth Factors | 2007 |
[Acute lymphoblastic leukemia with Philadelphia chromosome: treatment with kinase inhibitors].
Topics: Alkyl and Aryl Transferases; Antineoplastic Agents; Benzamides; Benzenesulfonates; Dasatinib; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Humans; Imatinib Mesylate; Indoles; Niacinamide; Phenylurea Compounds; Piperazines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Kinase Inhibitors; Pyridines; Pyrimidines; Pyrroles; Sorafenib; Sunitinib; Thiazoles | 2007 |
1 trial(s) available for pyrroles and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Potent obatoclax cytotoxicity and activation of triple death mode killing across infant acute lymphoblastic leukemia.
Topics: Antineoplastic Agents; Apoptosis; Autophagy; Cell Line, Tumor; Drug Resistance, Neoplasm; Gene Expression Regulation, Leukemic; Histone-Lysine N-Methyltransferase; Humans; Indoles; Infant; Infant, Newborn; Myeloid-Lymphoid Leukemia Protein; Necrosis; Oncogene Proteins, Fusion; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; Pyrroles | 2013 |
8 other study(ies) available for pyrroles and Acute Lymphoid Leukemia
| Article | Year |
|---|---|
Targeting EIF4E signaling with ribavirin in infant acute lymphoblastic leukemia.
Topics: Cell Line, Tumor; Child, Preschool; Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-4E; Gene Expression Profiling; Gene Expression Regulation, Leukemic; Humans; Indoles; Infant; Microarray Analysis; Molecular Targeted Therapy; Multigene Family; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Biosynthesis; Pyrroles; Ribavirin; Signal Transduction | 2019 |
[Bortezomib and obatoclax for dual blockade of protein degradation pathways show synergistic anti-tumor effect in human acute T lymphoblastic leukemia cells].
Topics: Antineoplastic Agents; Apoptosis; Bortezomib; Cell Line, Tumor; Drug Synergism; Endoplasmic Reticulum Chaperone BiP; Humans; Indoles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proteolysis; Proto-Oncogene Proteins c-bcl-2; Pyrroles | 2019 |
The pyrrolo-1,5-benzoxazepine, PBOX-15, enhances TRAIL‑induced apoptosis by upregulation of DR5 and downregulation of core cell survival proteins in acute lymphoblastic leukaemia cells.
Topics: Apoptosis; CASP8 and FADD-Like Apoptosis Regulating Protein; Caspase 8; Cell Line, Tumor; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Leukemic; Humans; Myeloid Cell Leukemia Sequence 1 Protein; Oxazepines; Phosphatidylinositol 3-Kinases; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrroles; Receptors, TNF-Related Apoptosis-Inducing Ligand; Signal Transduction; TNF-Related Apoptosis-Inducing Ligand | 2016 |
Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance.
Topics: Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Beclin-1; Dexamethasone; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Glucocorticoids; Humans; Indoles; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Nuclear Pore Complex Proteins; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins c-bcl-2; Pyrroles; RNA-Binding Proteins; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2010 |
Have chemosensitizing strategies for multidrug-resistant childhood acute lymphoblastic leukemia come of age?
Topics: Antineoplastic Agents; Clinical Trials, Phase I as Topic; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Indoles; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrroles | 2010 |
GX15-070 (obatoclax) overcomes glucocorticoid resistance in acute lymphoblastic leukemia through induction of apoptosis and autophagy.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Autophagy; Autophagy-Related Protein 5; bcl-2 Homologous Antagonist-Killer Protein; Beclin-1; Cell Line, Tumor; Drug Resistance, Neoplasm; Glucocorticoids; Humans; Indoles; Membrane Proteins; Microtubule-Associated Proteins; Myeloid Cell Leukemia Sequence 1 Protein; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Proto-Oncogene Proteins c-bcl-2; Pyrroles; RNA Interference; RNA, Small Interfering | 2010 |
The microtubule targeting agent PBOX-15 inhibits integrin-mediated cell adhesion and induces apoptosis in acute lymphoblastic leukaemia cells.
Topics: Apoptosis; Blotting, Western; Cell Adhesion; Cell Cycle Checkpoints; Cell Movement; Cell Proliferation; Flow Cytometry; Fluorescent Antibody Technique; Humans; Integrins; Microtubules; Oxazepines; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyrroles; Tumor Cells, Cultured | 2013 |
Cerivastatin triggers tumor-specific apoptosis with higher efficacy than lovastatin.
Topics: Acute Disease; Apoptosis; Atorvastatin; Cell Division; Dose-Response Relationship, Drug; Fatty Acids, Monounsaturated; Fluvastatin; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Indoles; Leukemia, Myeloid; Lovastatin; Neoplasms; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Pyridines; Pyrroles; Sensitivity and Specificity; Tumor Cells, Cultured | 2001 |