pyroxamide has been researched along with Disease Models, Animal in 3 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pyroxamide is a potent inhibitor of affinity-purified HDAC1 (ID(50) = 100 nM) and causes the accumulation of acetylated core histones in MEL cells cultured with the agent." | 1.31 | Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase. ( Agus, DB; Breslow, R; Butler, LM; Cordon-Cardo, C; Drobnjak, M; Higgins, B; Kutko, MC; LaQuaglia, MP; Marks, PA; Richon, VM; Rifkind, RA; Scher, HI; Tolentino, TR; Webb, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Einsiedel, HG | 1 |
| Kawan, L | 1 |
| Eckert, C | 1 |
| Witt, O | 1 |
| Fichtner, I | 1 |
| Henze, G | 1 |
| Seeger, K | 1 |
| Butler, LM | 1 |
| Webb, Y | 1 |
| Agus, DB | 1 |
| Higgins, B | 1 |
| Tolentino, TR | 1 |
| Kutko, MC | 1 |
| LaQuaglia, MP | 1 |
| Drobnjak, M | 1 |
| Cordon-Cardo, C | 1 |
| Scher, HI | 1 |
| Breslow, R | 1 |
| Richon, VM | 1 |
| Rifkind, RA | 1 |
| Marks, PA | 1 |
3 other studies available for pyroxamide and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Histone deacetylase inhibitors have antitumor activity in two NOD/SCID mouse models of B-cell precursor childhood acute lymphoblastic leukemia.
Topics: Aminopyridines; Animals; Antineoplastic Agents; Disease Models, Animal; Enzyme Inhibitors; Histone D | 2006 |
Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase.
Topics: Acetylation; Aminopyridines; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Ce | 2001 |