pyroxamide has been researched along with Cancer of Prostate in 2 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Available tools for prostate cancer (PC) prognosis are suboptimal but may be improved by better knowledge about genes driving tumor aggressiveness." | 1.62 | FRMD6 has tumor suppressor functions in prostate cancer. ( Borre, M; Cieza-Borrella, C; Dagnaes-Hansen, F; Eeles, R; Haldrup, J; Hedensted, S; Jakobsson, ME; Kote-Jarai, Z; Norgaard, M; Olsen, JV; Riedel, M; Sorensen, KD; Strand, SH; Thomsen, M; Ulhoi, BP, 2021) |
| "Pyroxamide is a potent inhibitor of affinity-purified HDAC1 (ID(50) = 100 nM) and causes the accumulation of acetylated core histones in MEL cells cultured with the agent." | 1.31 | Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase. ( Agus, DB; Breslow, R; Butler, LM; Cordon-Cardo, C; Drobnjak, M; Higgins, B; Kutko, MC; LaQuaglia, MP; Marks, PA; Richon, VM; Rifkind, RA; Scher, HI; Tolentino, TR; Webb, Y, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haldrup, J | 1 |
| Strand, SH | 1 |
| Cieza-Borrella, C | 1 |
| Jakobsson, ME | 1 |
| Riedel, M | 1 |
| Norgaard, M | 1 |
| Hedensted, S | 1 |
| Dagnaes-Hansen, F | 1 |
| Ulhoi, BP | 1 |
| Eeles, R | 1 |
| Borre, M | 1 |
| Olsen, JV | 1 |
| Thomsen, M | 1 |
| Kote-Jarai, Z | 1 |
| Sorensen, KD | 1 |
| Butler, LM | 1 |
| Webb, Y | 1 |
| Agus, DB | 1 |
| Higgins, B | 1 |
| Tolentino, TR | 1 |
| Kutko, MC | 1 |
| LaQuaglia, MP | 1 |
| Drobnjak, M | 1 |
| Cordon-Cardo, C | 1 |
| Scher, HI | 1 |
| Breslow, R | 1 |
| Richon, VM | 1 |
| Rifkind, RA | 1 |
| Marks, PA | 1 |
2 other studies available for pyroxamide and Cancer of Prostate
| Article | Year |
|---|---|
FRMD6 has tumor suppressor functions in prostate cancer.
Topics: Aged; Aminopyridines; Animals; Cell Proliferation; Cytoskeletal Proteins; DNA Methylation; Down-Regu | 2021 |
Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase.
Topics: Acetylation; Aminopyridines; Animals; Antineoplastic Agents; Cell Differentiation; Cell Division; Ce | 2001 |