pyrophosphate and Pyelonephritis

Topics: Adolescent; Adult; Chlormerodrin; Clinical Trials as Topic; Diphosphates; Female; Humans; Male; Mercury Radioisotopes; Middle Aged; Pyelonephritis; Radionuclide Imaging; Spine; Technetium

Nephroscintigraphy using a 67Ga-citrate complex and 99mTc-pyrophosphate was performed in 88 patients with acute pyelonephritis. Nuclide hyperfixation was revealed in 97.8% of the cases. Three groups of patients were singled out on the basis of the intensity of incorporation and nature of the distribution of the radiopharmaceuticals (RP) in the kidneys. In the 1st group the RP incorporation was insignificant but higher than normal values; the RP distribution in the affected kidney was diffuse-inhomogenous. These changes were considered to be typical of acute serous pyelonephritis. In the 2nd and 3rd groups a sharp rise of the RP accumulation was noted, being typical of acute purulent pyelonephritis. One could distinguish between diffuse and focal lesions by the picture of the RP distribution in the renal parenchyma. Diuresis stimulation made it possible to differentiate an actual nuclide fixation during inflammation from nuclide mechanical retention as a result of urine outflow disorder. According to the authors, both radiopharmaceuticals could be applied for the diagnosis of acute pyelonephritis as well as for differential diagnosis of various forms of the disease.

Topics: Acute Disease; Adult; Diphosphates; Female; Gallium Radioisotopes; Humans; Male; Middle Aged; Pyelonephritis; Radionuclide Imaging; Technetium; Technetium Tc 99m Pyrophosphate

Topics: Adult; Aged; Diphosphates; Female; Furosemide; Gallium Radioisotopes; Humans; Iodohippuric Acid; Kidney; Male; Middle Aged; Pyelonephritis; Radionuclide Imaging; Technetium; Technetium Tc 99m Pyrophosphate; Time Factors