pyrophosphate has been researched along with Mesenteric-Vascular-Occlusion* in 2 studies
2 other study(ies) available for pyrophosphate and Mesenteric-Vascular-Occlusion
| Article | Year |
|---|---|
Early imaging of experimental intestinal infarction with 99mTc-pyrophosphate.
Extensive mucosal small-bowel infarction was produced in 8 dogs by occluding the cranial mesenteric artery. After one hour of reperfusion, 15 mCi (555 MBq) of 99mTc-pyrophosphate was intra-arterially injected into 4 dogs and venously into the other 4. Positive images were obtained in all dogs except 1 which had received an intravenous injection. Diagnostic images were obtained consistently as early as 15 minutes after injection, and the infarcted bowel could still be visualized two hours later. The average tracer content in infarcted small bowel was 0.015% I.D./g. This was about eight times the uptake found in normal dogs. The results show that experimental small-bowel infarction can be detected as early as five hours after the onset of ischemia. Topics: Animals; Diphosphates; Disease Models, Animal; Dogs; Infarction; Intestinal Mucosa; Intestine, Small; Male; Mesenteric Arteries; Mesenteric Vascular Occlusion; Radionuclide Imaging; Technetium | 1979 |
99mTc-pyrophosphate imaging in experimental mesenteric infarction: relationship of tracer uptake to the degree of ischemic injury.
Four-hour balloon occlusion of the cranial mesenteric artery in 13 dogs produced a spectrum of widespread ischemic injury to the small bowel ranging from superficial mucosal infarction to transmural infarction. Twenty-four hours after the beginning of balloon occlusion, 15 mCl of 99mTc-pyrophosphate was injected into the cranial mesenteric artery in 8 dogs and into a peripheral vein in 5. Gamma camera imaging of the abdomen followed three hours later. Four of 8 dogs injected intra-arterially showed positive images with full-thickness mucosal or transmural infarction. The 4 intravenously injected dogs with positive images had transmural infarction. Only minimal ischemic injury with superficial mucosal infarction was found in the 5 dogs with negative images. Tracer uptake per gram infarcted tissue was highest after intra-arterial injection. It was concluded that 99mTc-pyrophosphate allows external imaging of extensive intestinal infarctions after both intra-arterial and intravenous injection. Topics: Animals; Diphosphates; Dogs; Infarction; Intestines; Mesenteric Vascular Occlusion; Mesentery; Radionuclide Imaging; Technetium | 1978 |