pyrophosphate and Giant-Cell-Tumors

Radiologic studies of 50 giant cell tumors of bone in 48 patients were useful in assessing the anatomic extent for planning surgical treatment. Contrast-enhanced computed tomography (CT) provided the most useful and complete evaluation, including soft tissue extent and relationship to major vessels. Angiography was useful when the extraosseous extent and vascular relationships were not entirely clear on CT. Arthro-tomography was the best way to evaluate tumor invasion through subchondral cortex and articular cartilage. Reactive soft tissues, with edema and hyperemia, were difficult to distinguish from tumor tissue on CT and angiograms. Bone scintigrams often showed intense uptake beyond the true tumor limits.

Topics: Adolescent; Adult; Angiography; Bone and Bones; Bone Neoplasms; Diphosphates; Female; Giant Cell Tumors; Humans; Male; Middle Aged; Polyphosphates; Radionuclide Imaging; Technetium; Technetium Compounds; Technetium Tc 99m Pyrophosphate; Tomography, X-Ray; Tomography, X-Ray Computed

Topics: Bone Neoplasms; Chondroblastoma; Chondroma; Diphosphates; Evaluation Studies as Topic; Giant Cell Tumors; Humans; Multiple Myeloma; Osteoma, Osteoid; Radionuclide Imaging; Sarcoma; Strontium Radioisotopes; Technetium; Technetium Tc 99m Pyrophosphate

Topics: Adolescent; Adult; Aged; Bone Neoplasms; Child; Diphosphates; Female; Giant Cell Tumors; Hodgkin Disease; Humans; Male; Middle Aged; Osteoma, Osteoid; Radionuclide Imaging; Sarcoma; Technetium