Page last updated: 2024-09-02

pyronaridine and Malaria, Falciparum

pyronaridine has been researched along with Malaria, Falciparum in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	14 (25.00)	18.2507
2000's	8 (14.29)	29.6817
2010's	27 (48.21)	24.3611
2020's	7 (12.50)	2.80

Authors

Authors	Studies
Fidock, DA; Flannery, EL; Winzeler, EA	1
Andrews, KT; Antonova-Koch, Y; Avery, VM; Diedrich, D; Duffy, S; Fisher, G; Gebru, T; Hansen, FK; Held, J; Hesping, E; Kurz, T; Meister, S; Schöler, A; Stenzel, K; Winzeler, EA	1
Avery, VM; Dans, MG; de Koning-Ward, TF; Duffy, S; Gancheva, MR; Gilson, PR; Lowes, KN; Ngo, A; Nguyen, W; Romeo, O; Sabroux, HJ; Sleebs, BE; Wilson, DW	1
Avery, VM; Challis, MP; Creek, DJ; De Paoli, A; Devine, SM; Kigotho, JK; MacRaild, CA; Norton, RS; Scammells, PJ; Siddiqui, G	1
Chu, WY; Dorlo, TPC	1
Badolo, L; Dhingra, SK; Fidock, DA; Giddins, MJ; Greco, B; Gumpp, C; Jonat, B; Oeuvray, C; Rottmann, M; Spangenberg, T; Yin, X	1
Bailly, C	1
Clark, RL	1
Mahotorn, K; Mungthin, M; Ruang-Areerate, T; Sittichot, N; Suwandittakul, N; Tan-Ariya, P; Thita, T	1
Choy, F; Makio, N; Mens, P; Okach, S; Omweri, G; Osoti, V; Roth, JM; Sawa, P; Schallig, HDFH	1
Bousema, T; Bradley, J; Makio, N; Mens, PF; Omweri, G; Osoti, V; Roth, JM; Sawa, P; Schallig, HDFH	1
Hine, P; Pryce, J	1
Fidock, DA; Okombo, J	1
Bustos, MD; Cong Tran, D; Hong Huynh, Q; Khim, N; Quang Bui, P; Quang Nguyen, T; Ringwald, P; Thanh Le, D; Thanh Tran, D; Thi Ta, T; Van Truong, H; Witkowski, B	1
Arbe-Barnes, S; Borghini-Fuhrer, I; Craft, CJ; Duparc, S; Fleckenstein, L; Miller, RM; Shin, CS	1
Arzika, I; Fandeur, T; Guillebaud, J; Issaka, M; Maazou, A; Salissou, A; Specht, S; Zamanka, H	1
Cremers, S; Fidock, DA; Henrich, PP; Kyle, DE; O'Brien, C; Sáenz, FE	1
Bukirwa, H; Kramer, CV; Nair, S; Sinclair, D; Tharyan, P; Unnikrishnan, B	1
Cui, L; Gupta, B; Miao, J; Sun, L; Wang, Z; Xu, S; Yang, Z	1
Ashley, EA; Blessborn, D; Chairat, K; Day, NP; Hanboonkunupakarn, B; Jittamala, P; Lee, SJ; Nosten, F; Panapipat, S; Pukrittayakamee, S; Tarning, J; Thana, P; White, NJ	1
Amalvict, R; Benoit, N; Briolant, S; Gaillard, T; Madamet, M; Pascual, A; Pradines, B; Travers, D	1
Ayyoub, A; Borghini-Fuhrer, I; Djimde, AA; Duparc, S; Fleckenstein, L; Methaneethorn, J; Ramharter, M; Shin, JS; Tekete, M	1
Borghini Fuhrer, I; Canavati, SE; Denis, MB; Dondorp, AM; Duparc, S; Heng, P; Huy, R; Khim, N; Kim, S; Leang, R; Menard, D; Ringwald, P; Tol, B; Vestergaard, LS	1
Amalvict, R; Benoit, N; Briolant, S; Diatta, B; Diawara, S; Diémé, Y; Fall, B; Fall, M; Gendrot, M; Kounta, MB; Madamet, M; Nakoulima, A; Pradines, B; Wade, B; Wade, KA	1
Bélard, S; Cisse, B; Fleckenstein, L; Glasenapp, Iv; Issifou, S; Kammer, J; Koumba, PK; Kremsner, PG; Kurth, F; Lell, B; Mordmüller, B; Nemeth, J; Oeuvray, C; Ramharter, M; Schlie, M; Schreier, AC	1
Bélard, S; Kremsner, PG; Kurth, F; Mordmüller, B; Pongratz, P; Ramharter, M	1
Nosten, FH	1
Bedu-Addo, G; Bhatt, KM; Borghini-Fuhrer, I; Bustos, DG; Duparc, S; Fleckenstein, L; Gaye, O; Kayentao, K; Sesay, SS; Shin, CS; Thompson, R; Tjitra, E; Tshefu, AK	1
Nau, JY	1
Basra, A; Bélard, S; Kurth, F; Ramharter, M	1
Kiara, SM; Mwai, L; Nzila, A; Ochola, LI; Ohuma, E; Okombo, J; Pole, L	1
Abdulla, S; Binh, TQ; Borghini-Fuhrer, I; Duparc, S; Fleckenstein, L; Pénali, LK; Phyo, AP; Poravuth, Y; Rueangweerayut, R; Shin, CS; Tien, NT; Tinto, H; Uthaisin, C; Valecha, N	1
Arbe-Barnes, SJ; Borghini-Fuhrer, I; Craft, JC; Croft, SL; Duparc, S; Fleckenstein, L; Rim, HJ; Shin, CS	1
Liu, H; Wang, J; Zhang, CL; Zhou, HN	1
Holtermann, MK	1
Bhatt, KM; Borghini-Fuhrer, I; Bustos, MD; de Salazar, PM; Doumbo, OK; Duparc, S; Fleckenstein, L; Kayentao, K; Kimani, J; Kokolomami, JH; Offianan, AT; Ouédraogo, A; Pénali, LK; Quicho, F; Ramharter, M; Shin, CS; Tiono, AB; Tshefu, AK	1
Agnamey, P; Brasseur, P; Galega, PF; Moyou, SR	1
Chen, C; Chen, PL; Chen, WJ; Feng, XP; Lin, SG; Liu, DQ; Liu, J; Wu, HM	1
Feng, XP; Liu, DQ	1
Karupiah, S; Mansor, SM; Nair, NK; Navaratnam, V; Olliaro, PL; Ramanathan, S; Wernsdorfer, WH	1
Feng, XP; Liu, DQ; Liu, RJ; Zhang, CY	1
Winstanley, P	1
Basco, L; Bickii, J; Ringwald, P	1
Peters, W	1
Kyle, D; Looareesuwan, S; Olliaro, P; Wernsdorfer, W	1
Foster, S	1
Kyle, DE; Looareesuwan, S; Vanijanonta, S; Viravan, C; Wernsdorfer, WH; Wilairatana, P	1
Chang, C; Kano, S; Kawai, S; Suzuki, M	1
Basco, LK; Bickii, J; Ringwald, P	1
Doury, JC; Kombila, M; Lebeau, C; Mabika Mamfoumbi, M; Mourou Mbina, JR; Owono Medang, M; Parzy, D; Pradines, B	1
Basco, LK; Meche, FS; Ringwald, P	1
Basco, LK; Ringwald, P	1
Auparakkitanon, S; Chavalitshewinkoon-Petmitr, P; Pongvilairat, G; Wilairat, P	1
Huang, K; Li, C; Liu, D; Yang, H; Zhang, C	1
Fan, B; Huang, Z; Ma, X; Wen, Y; Yang, J; Yang, Z; Zhao, W	1
Chen, C; Zheng, X	1

Reviews

8 review(s) available for pyronaridine and Malaria, Falciparum

Article	Year
Using genetic methods to define the targets of compounds with antimalarial activity. Journal of medicinal chemistry, 2013, Oct-24, Volume: 56, Issue:20 Topics: Animals; Anopheles; Antimalarials; Drug Resistance; Genetic Association Studies; Genome, Protozoan; Humans; Malaria, Falciparum; Molecular Targeted Therapy; Plasmodium falciparum	2013
Pyronaridine: a review of its clinical pharmacology in the treatment of malaria. The Journal of antimicrobial chemotherapy, 2023, 10-03, Volume: 78, Issue:10 Topics: Antimalarials; Child; Chloroquine; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy	2023
Pyronaridine: An update of its pharmacological activities and mechanisms of action. Biopolymers, 2021, Volume: 112, Issue:4 Topics: Animals; Antimalarials; Artesunate; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum	2021
Animal Embryotoxicity Studies of Key Non-Artemisinin Antimalarials and Use in Women in the First Trimester. Birth defects research, 2017, Aug-15, Volume: 109, Issue:14 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Drug Combinations; Female; Humans; Malaria; Malaria, Falciparum; Naphthyridines; Pregnancy; Pregnancy Trimester, First; Pyrimethamine; Quinine; Quinolines; Rabbits; Rats; Sulfadoxine; Teratogens	2017
Pyronaridine-artesunate for treating uncomplicated Plasmodium falciparum malaria. The Cochrane database of systematic reviews, 2019, 01-08, Volume: 1 Topics: Adult; Amodiaquine; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combination; Humans; Liver; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Randomized Controlled Trials as Topic	2019
Artesunate plus pyronaridine for treating uncomplicated Plasmodium falciparum malaria. The Cochrane database of systematic reviews, 2014, Mar-04, Issue:3 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Therapy, Combination; Ethanolamines; Fluorenes; Humans; Liver; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Randomized Controlled Trials as Topic	2014
Pyronaridine-artesunate combination therapy for the treatment of malaria. Current opinion in infectious diseases, 2011, Volume: 24, Issue:6 Topics: Antimalarials; Artemisinins; Drug Combinations; Humans; Malaria, Falciparum; Malaria, Vivax; Naphthyridines	2011
Development of the new antimalarial drug pyronaridine: a review. Biomedical and environmental sciences : BES, 1992, Volume: 5, Issue:2 Topics: Administration, Oral; Animals; Antimalarials; Cardiovascular System; Chloroquine; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Haplorhini; Humans; Injections, Intramuscular; Lethal Dose 50; Malaria, Falciparum; Mice; Naphthyridines; Pyrimethamine; Rabbits; Sulfadoxine	1992

Trials

16 trial(s) available for pyronaridine and Malaria, Falciparum

Article	Year
Pyronaridine-artesunate and artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children: a randomized controlled non-inferiority trial. Malaria journal, 2018, May-15, Volume: 17, Issue:1 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Kenya; Malaria, Falciparum; Male; Naphthyridines	2018
Plasmodium falciparum gametocyte dynamics after pyronaridine-artesunate or artemether-lumefantrine treatment. Malaria journal, 2018, Jun-04, Volume: 17, Issue:1 Topics: Adolescent; Antimalarials; Artemether, Lumefantrine Drug Combination; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Kenya; Malaria, Falciparum; Male; Naphthyridines; Plasmodium falciparum; Reverse Transcriptase Polymerase Chain Reaction; Self-Sustained Sequence Replication	2018
Pyronaridine-artesunate Efficacy and Safety in Uncomplicated Plasmodium falciparum Malaria in Areas of Artemisinin-resistant Falciparum in Viet Nam (2017-2018). Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 05-06, Volume: 70, Issue:10 Topics: Adult; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Prospective Studies; Vietnam	2020
Pharmacokinetic interactions between primaquine and pyronaridine-artesunate in healthy adult Thai subjects. Antimicrobial agents and chemotherapy, 2015, Volume: 59, Issue:1 Topics: Administration, Oral; Adult; Antimalarials; Artemisinins; Artesunate; Cross-Over Studies; Drug Interactions; Drug Therapy, Combination; Female; Humans; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Primaquine; Thailand; Young Adult	2015
Population Pharmacokinetics of Pyronaridine in Pediatric Malaria Patients. Antimicrobial agents and chemotherapy, 2015, Dec-14, Volume: 60, Issue:3 Topics: Adolescent; Antimalarials; Area Under Curve; Artemisinins; Artesunate; Child; Child, Preschool; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Models, Theoretical; Naphthyridines	2015
Efficacy and safety of a fixed-dose oral combination of pyronaridine-artesunate compared with artemether-lumefantrine in children and adults with uncomplicated Plasmodium falciparum malaria: a randomised non-inferiority trial. Lancet (London, England), 2010, Apr-24, Volume: 375, Issue:9724 Topics: Adolescent; Adult; Africa; Antimalarials; Artemether; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Double-Blind Method; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Treatment Outcome; Young Adult	2010
Pyronaridine-artesunate versus mefloquine plus artesunate for malaria. The New England journal of medicine, 2012, Apr-05, Volume: 366, Issue:14 Topics: Adolescent; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Drug Combinations; Drug Resistance; Female; Humans; Intention to Treat Analysis; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Mefloquine; Middle Aged; Naphthyridines; Proportional Hazards Models; Young Adult	2012
Pyronaridine-artesunate granules versus artemether-lumefantrine crushed tablets in children with Plasmodium falciparum malaria: a randomized controlled trial. Malaria journal, 2012, Oct-31, Volume: 11 Topics: Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Artesunate; Child; Child, Preschool; Dosage Forms; Drug Combinations; Ethanolamines; Female; Fluorenes; Humans; Infant; Malaria, Falciparum; Male; Naphthyridines; Parasite Load; Recurrence; Tablets; Treatment Outcome	2012
[Study on treatment of multi-drug resistant falciparum malaria by using a combination of dihydroartemisinin and pyronaridine]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2002, Volume: 20, Issue:4 Topics: Adolescent; Adult; Aged; Antimalarials; Artemisinins; Child; Child, Preschool; Double-Blind Method; Drug Resistance, Multiple; Drug Therapy, Combination; Humans; Infant; Malaria, Falciparum; Middle Aged; Naphthyridines; Sesquiterpenes	2002
A new and simple solid-phase extraction method for LC determination of pyronaridine in human plasma. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2005, Sep-25, Volume: 824, Issue:1-2 Topics: Administration, Oral; Antimalarials; Area Under Curve; Calibration; Chromatography, Liquid; Half-Life; Humans; Malaria, Falciparum; Naphthyridines; Regression Analysis; Reproducibility of Results; Time Factors	2005
Randomised trial of pyronaridine versus chloroquine for acute uncomplicated falciparum malaria in Africa. Lancet (London, England), 1996, Jan-06, Volume: 347, Issue:8993 Topics: Administration, Oral; Adolescent; Adult; Animals; Antimalarials; Cameroon; Chloroquine; Drug Resistance; Female; Follow-Up Studies; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Plasmodium falciparum; Treatment Outcome	1996
Clinical study of pyronaridine for the treatment of acute uncomplicated falciparum malaria in Thailand. The American journal of tropical medicine and hygiene, 1996, Volume: 54, Issue:2 Topics: Acute Disease; Adolescent; Adult; Antimalarials; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Naphthyridines	1996
Efficacy of oral pyronaridine for the treatment of acute uncomplicated falciparum malaria in African children. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1998, Volume: 26, Issue:4 Topics: Administration, Oral; Adolescent; Antimalarials; Blood Cell Count; Cameroon; Child; Child, Preschool; Female; Humans; Malaria, Falciparum; Male; Microbial Sensitivity Tests; Naphthyridines	1998
Short report: effects of pyronaridine on gametocytes in patients with acute uncomplicated falciparum malaria. The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:3 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Humans; Malaria, Falciparum; Naphthyridines; Parasitemia; Plasmodium falciparum	1999
Molecular epidemiology of malaria in Yaounde, Cameroon V. analysis of the omega repetitive region of the plasmodium falciparum CG2 gene and chloroquine resistance. The American journal of tropical medicine and hygiene, 1999, Volume: 61, Issue:5 Topics: Adolescent; Adult; Animals; Antimalarials; Cameroon; Child; Chloroquine; DNA Primers; DNA, Protozoan; Drug Resistance; Electrophoresis, Agar Gel; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Naphthyridines; Parasitemia; Phenanthrenes; Plasmodium falciparum; Polymerase Chain Reaction; Regression Analysis; Repetitive Sequences, Nucleic Acid; Scintillation Counting; Sequence Analysis, DNA	1999
Development of the new antimalarial drug pyronaridine: a review. Biomedical and environmental sciences : BES, 1992, Volume: 5, Issue:2 Topics: Administration, Oral; Animals; Antimalarials; Cardiovascular System; Chloroquine; Dogs; Drug Evaluation; Drug Evaluation, Preclinical; Drug Resistance; Drug Therapy, Combination; Haplorhini; Humans; Injections, Intramuscular; Lethal Dose 50; Malaria, Falciparum; Mice; Naphthyridines; Pyrimethamine; Rabbits; Sulfadoxine	1992

Other Studies

33 other study(ies) available for pyronaridine and Malaria, Falciparum

Article	Year
One-pot, multi-component synthesis and structure-activity relationships of peptoid-based histone deacetylase (HDAC) inhibitors targeting malaria parasites. European journal of medicinal chemistry, 2018, Oct-05, Volume: 158 Topics: Acetylation; Antimalarials; Hep G2 Cells; Histone Deacetylase Inhibitors; Histones; Humans; Malaria, Falciparum; Peptoids; Plasmodium falciparum; Protozoan Proteins	2018
Structure activity refinement of phenylsulfonyl piperazines as antimalarials that block erythrocytic invasion. European journal of medicinal chemistry, 2021, Mar-15, Volume: 214 Topics: Animals; Antimalarials; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Erythrocytes; Hep G2 Cells; Humans; Malaria, Falciparum; Mice; Microsomes, Liver; Molecular Structure; Parasitic Sensitivity Tests; Piperazines; Plasmodium falciparum; Plasmodium knowlesi; Solubility; Structure-Activity Relationship	2021
Discovery and development of 2-aminobenzimidazoles as potent antimalarials. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antimalarials; Benzimidazoles; Dose-Response Relationship, Drug; Drug Discovery; HEK293 Cells; Humans; Malaria, Falciparum; Molecular Structure; Parasitic Sensitivity Tests; Plasmodium falciparum; Structure-Activity Relationship	2021
Preclinical Antimalarial Combination Study of M5717, a Plasmodium falciparum Elongation Factor 2 Inhibitor, and Pyronaridine, a Hemozoin Formation Inhibitor. Antimicrobial agents and chemotherapy, 2020, 03-24, Volume: 64, Issue:4 Topics: Animals; Antimalarials; Drug Resistance; Drug Therapy, Combination; Hemeproteins; Malaria, Falciparum; Mice; Mice, SCID; Naphthyridines; Peptide Elongation Factor 2; Plasmodium falciparum; Quinolines	2020
In Vitro Sensitivity of Pyronaridine in Thai Isolates of The American journal of tropical medicine and hygiene, 2018, Volume: 98, Issue:1 Topics: Antimalarials; Dose-Response Relationship, Drug; Drug Resistance; Drug Resistance, Multiple; Genes, Protozoan; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Thailand	2018
Pyronaridine-artesunate Shows Promise as an Effective and Well-tolerated Treatment for Artemisinin-resistant Plasmodium falciparum Malaria. Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2020, 05-06, Volume: 70, Issue:10 Topics: Artemisinins; Artesunate; Humans; Malaria, Falciparum; Naphthyridines; Vietnam	2020
Safety and efficacy of pyronaridine-artesunate in uncomplicated acute malaria: an integrated analysis of individual patient data from six randomized clinical trials. Malaria journal, 2013, Feb-21, Volume: 12 Topics: Adolescent; Adult; Africa; Antimalarials; Artemisinins; Artesunate; Asia; Child; Child, Preschool; Clinical Trials, Phase III as Topic; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Malaria; Malaria, Falciparum; Malaria, Vivax; Male; Middle Aged; Naphthyridines; Randomized Controlled Trials as Topic; Treatment Outcome; Young Adult	2013
Ex vivo responses of Plasmodium falciparum clinical isolates to conventional and new antimalarial drugs in Niger. Antimicrobial agents and chemotherapy, 2013, Volume: 57, Issue:7 Topics: Amodiaquine; Antimalarials; Artemisinins; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Naphthyridines; Niger; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines	2013
Evidence for pyronaridine as a highly effective partner drug for treatment of artemisinin-resistant malaria in a rodent model. Antimicrobial agents and chemotherapy, 2014, Volume: 58, Issue:1 Topics: Amodiaquine; Animals; Antimalarials; Artemisinins; Artesunate; Drug Combinations; Drug Resistance; Female; Flow Cytometry; Malaria, Falciparum; Mefloquine; Mice; Naphthyridines	2014
Plasmodium falciparum multidrug resistance protein 1 (pfmrp1) gene and its association with in vitro drug susceptibility of parasite isolates from north-east Myanmar. The Journal of antimicrobial chemotherapy, 2014, Volume: 69, Issue:8 Topics: Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Base Sequence; Chloroquine; Drug Resistance; Ethanolamines; Fluorenes; Geography; Humans; Lumefantrine; Malaria, Falciparum; Mefloquine; Multidrug Resistance-Associated Proteins; Mutation; Myanmar; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Single Nucleotide; Selection, Genetic; Sequence Analysis, DNA	2014
Multinormal in vitro distribution of Plasmodium falciparum susceptibility to piperaquine and pyronaridine. Malaria journal, 2015, Feb-05, Volume: 14 Topics: Africa; Antimalarials; Drug Resistance; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Quinolines	2015
Efficacy and Safety of Pyronaridine-Artesunate for Treatment of Uncomplicated Plasmodium falciparum Malaria in Western Cambodia. Antimicrobial agents and chemotherapy, 2016, Volume: 60, Issue:7 Topics: Adolescent; Adult; Antimalarials; Artemisinins; Artesunate; Cambodia; Child; Female; Humans; Kaplan-Meier Estimate; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Young Adult	2016
Association between Polymorphisms in the Pf Antimicrobial agents and chemotherapy, 2017, Volume: 61, Issue:3 Topics: Amodiaquine; Antimalarials; Artemisinins; Artesunate; Asparagine; ATP-Binding Cassette Transporters; Chloroquine; Doxycycline; Drug Resistance; Ethanolamines; Fluorenes; Gene Expression; Humans; Inhibitory Concentration 50; Lumefantrine; Malaria, Falciparum; Mefloquine; Naphthyridines; Plasmodium falciparum; Polymorphism, Genetic; Protein Isoforms; Protozoan Proteins; Quinine; Quinolines; Repetitive Sequences, Amino Acid; Senegal	2017
Fixed-dose pyronaridine-artesunate combination for treatment of uncomplicated falciparum malaria in pediatric patients in Gabon. The Journal of infectious diseases, 2008, Sep-15, Volume: 198, Issue:6 Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Dose-Response Relationship, Drug; Drug Therapy, Combination; Drug Tolerance; Female; Gabon; Humans; Malaria, Falciparum; Male; Naphthyridines; Plasmodium falciparum; Polymerase Chain Reaction; Safety; Treatment Outcome	2008
In vitro activity of pyronaridine against Plasmodium falciparum and comparative evaluation of anti-malarial drug susceptibility assays. Malaria journal, 2009, Apr-23, Volume: 8 Topics: Administration, Oral; Adolescent; Animals; Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Biological Assay; Child; Child, Preschool; Chloroquine; Drug Evaluation, Preclinical; Enzyme-Linked Immunosorbent Assay; Female; Gabon; Humans; Infant; Malaria, Falciparum; Male; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Protozoan Proteins; Quinine; Regression Analysis	2009
Pyronaridine-artesunate for uncomplicated falciparum malaria. Lancet (London, England), 2010, Apr-24, Volume: 375, Issue:9724 Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Drug Combinations; Ethanolamines; Fluorenes; Humans; Lumefantrine; Malaria, Falciparum; Naphthyridines	2010
[A new antimalarial drug combination]. Revue medicale suisse, 2010, May-05, Volume: 6, Issue:247 Topics: Antimalarials; Artemisinins; Artesunate; Drug Combinations; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Treatment Outcome	2010
Baseline in vitro activities of the antimalarials pyronaridine and methylene blue against Plasmodium falciparum isolates from Kenya. Antimicrobial agents and chemotherapy, 2012, Volume: 56, Issue:2 Topics: Animals; Antimalarials; Humans; Kenya; Malaria, Falciparum; Methylene Blue; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Polymorphism, Genetic; Protozoan Proteins	2012
Review of pyronaridine anti-malarial properties and product characteristics. Malaria journal, 2012, Aug-09, Volume: 11 Topics: Antimalarials; China; Drug Therapy, Combination; Drug-Related Side Effects and Adverse Reactions; Humans; Malaria, Falciparum; Malaria, Vivax; Naphthyridines; Plasmodium falciparum; Plasmodium vivax; Treatment Outcome	2012
[In vitro sensitivity of Plasmodium falciparum isolates from China-Myanmar border region to chloroquine, piperaquine and pyronaridine]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2012, Feb-29, Volume: 30, Issue:1 Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; China; Chloroquine; Drug Resistance; Female; Humans; Malaria, Falciparum; Male; Middle Aged; Myanmar; Naphthyridines; Plasmodium falciparum; Quinolines; Young Adult	2012
[New combination therapy against malaria]. Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2012, Aug-21, Volume: 132, Issue:15 Topics: Africa; Antimalarials; Artemisinins; Artesunate; Asia; Drug Combinations; Drug Resistance; Global Health; Humans; Malaria, Falciparum; Mefloquine; Naphthyridines	2012
[Center of multidrug-resistant malaria in a forest zone of Cameroon revisited after 14 years]. Medecine tropicale : revue du Corps de sante colonial, 2002, Volume: 62, Issue:2 Topics: Amodiaquine; Animals; Cameroon; Chloroquine; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Naphthyridines; Plasmodium falciparum; Quinine; Trees	2002
[Factors affecting the in vitro microtest for drug sensitivity of Plasmodium falciparum]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2003, Volume: 21, Issue:4 Topics: Animals; Antimalarials; Artemisinins; Artesunate; Blood; Chloroquine; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Quinolines; Sesquiterpenes	2003
[Establishment of in vitro microtest for determining sensitivity of Plasmodium falciparum to pyronaridine]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 2006, Apr-30, Volume: 24, Issue:2 Topics: Animals; Antimalarials; China; Humans; Malaria, Falciparum; Naphthyridines; Parasitic Sensitivity Tests; Plasmodium falciparum; Treatment Outcome	2006
Pyronaridine: a promising drug for Africa? Lancet (London, England), 1996, Jan-06, Volume: 347, Issue:8993 Topics: Africa; Antimalarials; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Naphthyridines	1996
Pyronaridine against multiresistant falciparum malaria. Lancet (London, England), 1996, Mar-02, Volume: 347, Issue:9001 Topics: Antimalarials; Drug Resistance, Multiple; Humans; Malaria, Falciparum; Naphthyridines	1996
Pyronaridine. Lancet (London, England), 1996, Apr-27, Volume: 347, Issue:9009 Topics: Adult; Antimalarials; Cameroon; Clinical Trials as Topic; Humans; Malaria, Falciparum; Naphthyridines; Thailand	1996
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In vitro susceptibility of African isolates of Plasmodium falciparum from Gabon to pyronaridine. The American journal of tropical medicine and hygiene, 1999, Volume: 60, Issue:1 Topics: Adolescent; Amodiaquine; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Gabon; Humans; Infant; Malaria, Falciparum; Naphthyridines; Phenanthrenes; Plasmodium falciparum; Quinine	1999
Gametocytocidal activity of pyronaridine and DNA topoisomerase II inhibitors against multidrug-resistant Plasmodium falciparum in vitro. Parasitology international, 2000, Volume: 48, Issue:4 Topics: Amsacrine; Animals; Antimalarials; Chloroquine; Drug Resistance, Multiple; Enzyme Inhibitors; Etoposide; Humans; Inhibitory Concentration 50; Malaria, Falciparum; Mefloquine; Naphthyridines; Norfloxacin; Nucleic Acid Synthesis Inhibitors; Plasmodium falciparum; Primaquine; Proguanil; Pyrimethamine; Thailand; Topoisomerase II Inhibitors; Triazines	2000
[Longitudinal surveillance of sensitivity of Plasmodium falciparum to pyronaridine in south Yunnan]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1998, Volume: 16, Issue:2 Topics: Adolescent; Adult; Animals; Antimalarials; Child; Drug Resistance; Humans; Longitudinal Studies; Malaria, Falciparum; Middle Aged; Naphthyridines; Plasmodium falciparum; Recurrence; Sensitivity and Specificity	1998
[In vitro sensitivity of Plasmodium falciparum to chloroquine, piperaquine, pyronaridine and artesunate in Yuxi prefecture of Yunnan province]. Zhongguo ji sheng chong xue yu ji sheng chong bing za zhi = Chinese journal of parasitology & parasitic diseases, 1998, Volume: 16, Issue:6 Topics: Adolescent; Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Chloroquine; Drug Resistance; Female; Humans; In Vitro Techniques; Infant; Inhibitory Concentration 50; Malaria, Falciparum; Male; Middle Aged; Naphthyridines; Plasmodium falciparum; Quinolines; Sesquiterpenes	1998