pyrithione has been researched along with Ovarian Neoplasms in 2 studies
pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.
Ovarian Neoplasms: Tumors or cancer of the OVARY. These neoplasms can be benign or malignant. They are classified according to the tissue of origin, such as the surface EPITHELIUM, the stromal endocrine cells, and the totipotent GERM CELLS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using SKOV3 and ES2 cells, ovarian cancer cell lines that demonstrate varied degrees of resistance to known therapeutics, we show that zinc killing is time and concentration dependent." | 1.37 | Zinc is a potential therapeutic for chemoresistant ovarian cancer. ( Baldassare, J; Bastow, M; Klein, C; Kriedt, CL; Shah, M, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 1 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, M | 1 |
| Ding, Y | 1 |
| Ke, Y | 1 |
| Zeng, Y | 1 |
| Liu, N | 1 |
| Zhong, Y | 1 |
| Hua, X | 1 |
| Li, Z | 1 |
| Xiong, Y | 1 |
| Wu, C | 1 |
| Yu, H | 1 |
| Bastow, M | 1 |
| Kriedt, CL | 1 |
| Baldassare, J | 1 |
| Shah, M | 1 |
| Klein, C | 1 |
2 other studies available for pyrithione and Ovarian Neoplasms
| Article | Year |
|---|---|
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Human | 2020 |
Zinc is a potential therapeutic for chemoresistant ovarian cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Cycle Checkpoints; Cell Death; | 2011 |