Page last updated: 2024-10-21

pyrithione and Neoplasms

pyrithione has been researched along with Neoplasms in 3 studies

pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"More than 85% of (111)In remained in tumors, bound to cell cytoplasmic components of apparent molecular weights 250 and 6 kDa."1.32Role of lipid-soluble complexes in targeted tumor therapy. ( Coss, R; Howell, R; Leeper, DL; Liu, J; Rao, SP; Spana, G; Thakur, ML; Vassileva-Belnikolovska, D; Wachsberger, P, 2003)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Chaudhuri, A1
Mengji, R1
Venkatesh, Y1
Jana, A1
Pradeep Singh, ND1
Magda, D1
Lecane, P1
Wang, Z1
Hu, W1
Thiemann, P1
Ma, X1
Dranchak, PK1
Wang, X1
Lynch, V1
Wei, W1
Csokai, V1
Hacia, JG1
Sessler, JL1
Thakur, ML1
Coss, R1
Howell, R1
Vassileva-Belnikolovska, D1
Liu, J1
Rao, SP1
Spana, G1
Wachsberger, P1
Leeper, DL1

Other Studies

3 other studies available for pyrithione and Neoplasms

ArticleYear
An improved tumor-specific therapeutic strategy by the spatio-temporally controlled in situ formation of a Cu(ii) complex, leading to prompt cell apoptosis via photoactivation of a prodrug.
    Chemical communications (Cambridge, England), 2020, Apr-28, Volume: 56, Issue:33

    Topics: Antineoplastic Agents; Apoptosis; Biotin; Cell Line; Chelating Agents; Coordination Complexes; Coppe

2020
Synthesis and anticancer properties of water-soluble zinc ionophores.
    Cancer research, 2008, Jul-01, Volume: 68, Issue:13

    Topics: Animals; Antineoplastic Agents; Cell Proliferation; Cell Survival; Gene Expression Profiling; Gene E

2008
Role of lipid-soluble complexes in targeted tumor therapy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2003, Volume: 44, Issue:8

    Topics: Animals; Breast Neoplasms; Cell Line; Colorectal Neoplasms; Dose-Response Relationship, Radiation; D

2003