pyrithione has been researched along with Necrosis in 1 studies
pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.
Necrosis: The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study, we investigated the role of intracellular Zn level in the induction of apoptosis in human leukemia cells (HL-60 cells) using a Zn ionophore [pyrithione (Py)]." | 3.71 | Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells. ( Araragi, S; Higashimoto, M; Kondoh, M; Sato, M; Takiguchi, M; Tasaki, E; Watanabe, Y, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kondoh, M | 1 |
| Tasaki, E | 1 |
| Araragi, S | 1 |
| Takiguchi, M | 1 |
| Higashimoto, M | 1 |
| Watanabe, Y | 1 |
| Sato, M | 1 |
1 other study available for pyrithione and Necrosis
| Article | Year |
|---|---|
Requirement of caspase and p38MAPK activation in zinc-induced apoptosis in human leukemia HL-60 cells.
Topics: Apoptosis; Blotting, Western; Caspases; Cell Death; Cell Line; Dose-Response Relationship, Drug; Enz | 2002 |