pyrithione has been researched along with Mitochondrial Diseases in 1 studies
pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.
Mitochondrial Diseases: Diseases caused by abnormal function of the MITOCHONDRIA. They may be caused by mutations, acquired or inherited, in mitochondrial DNA or in nuclear genes that code for mitochondrial components. They may also be the result of acquired mitochondria dysfunction due to adverse effects of drugs, infections, or other environmental causes.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Mitochondrial diseases are systemic, prevalent and often fatal; yet treatments remain scarce." | 1.40 | Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders. ( Aiyar, RS; Antony, C; Blondel, M; Bohnert, M; Couplan, E; Courtin, F; di Rago, JP; Duvezin-Caubet, S; Evrard, J; Fritsch, ES; Funaya, C; Gagneur, J; Kucharczyk, R; Soubigou, F; St Onge, RP; Steinmetz, LM; Suresh, S; van der Laan, M; Voisset, C; von der Malsburg, K, 2014) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aiyar, RS | 1 |
| Bohnert, M | 1 |
| Duvezin-Caubet, S | 1 |
| Voisset, C | 1 |
| Gagneur, J | 1 |
| Fritsch, ES | 1 |
| Couplan, E | 1 |
| von der Malsburg, K | 1 |
| Funaya, C | 1 |
| Soubigou, F | 1 |
| Courtin, F | 1 |
| Suresh, S | 1 |
| Kucharczyk, R | 1 |
| Evrard, J | 1 |
| Antony, C | 1 |
| St Onge, RP | 1 |
| Blondel, M | 1 |
| di Rago, JP | 1 |
| van der Laan, M | 1 |
| Steinmetz, LM | 1 |
1 other study available for pyrithione and Mitochondrial Diseases
| Article | Year |
|---|---|
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders.
Topics: Antifungal Agents; Cell Nucleus; Databases, Pharmaceutical; Drug Repositioning; Gene Expression Regu | 2014 |