Page last updated: 2024-10-21

pyrithione and Leishmaniasis

pyrithione has been researched along with Leishmaniasis in 1 studies

pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.

Leishmaniasis: A disease caused by any of a number of species of protozoa in the genus LEISHMANIA. There are four major clinical types of this infection: cutaneous (Old and New World) (LEISHMANIASIS, CUTANEOUS), diffuse cutaneous (LEISHMANIASIS, DIFFUSE CUTANEOUS), mucocutaneous (LEISHMANIASIS, MUCOCUTANEOUS), and visceral (LEISHMANIASIS, VISCERAL).

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (100.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vieites, M1
Smircich, P1
Guggeri, L1
Marchán, E1
Gómez-Barrio, A1
Navarro, M1
Garat, B1
Gambino, D1

Other Studies

1 other study available for pyrithione and Leishmaniasis

ArticleYear
Synthesis and characterization of a pyridine-2-thiol N-oxide gold(I) complex with potent antiproliferative effect against Trypanosoma cruzi and Leishmania sp. insight into its mechanism of action.
    Journal of inorganic biochemistry, 2009, Volume: 103, Issue:10

    Topics: Animals; Antiprotozoal Agents; Cell Line; Cell Proliferation; Chagas Disease; Disease Models, Animal

2009