pyrithione has been researched along with Granulocytic Leukemia, Chronic in 2 studies
pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Muthyala, R | 1 |
| Shin, WS | 1 |
| Xie, J | 1 |
| Sham, YY | 1 |
| Lan, X | 1 |
| Zhao, C | 1 |
| Chen, X | 1 |
| Zhang, P | 1 |
| Zang, D | 1 |
| Wu, J | 1 |
| Chen, J | 1 |
| Long, H | 1 |
| Yang, L | 1 |
| Huang, H | 1 |
| Carter, BZ | 1 |
| Wang, X | 1 |
| Shi, X | 1 |
| Liu, J | 1 |
2 other studies available for pyrithione and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Discovery of 1-hydroxypyridine-2-thiones as selective histone deacetylase inhibitors and their potential application for treating leukemia.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Crystallography, X-Ray; Dose-Response | 2015 |
Nickel pyrithione induces apoptosis in chronic myeloid leukemia cells resistant to imatinib via both Bcr/Abl-dependent and Bcr/Abl-independent mechanisms.
Topics: Apoptosis; Caspases; Drug Resistance, Neoplasm; Fusion Proteins, bcr-abl; Heterografts; Humans; Imat | 2016 |