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pyrithione and Electron Transport Chain Deficiencies, Mitochondrial

pyrithione has been researched along with Electron Transport Chain Deficiencies, Mitochondrial in 1 studies

pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.

Research Excerpts

ExcerptRelevanceReference
"Mitochondrial diseases are systemic, prevalent and often fatal; yet treatments remain scarce."1.40Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders. ( Aiyar, RS; Antony, C; Blondel, M; Bohnert, M; Couplan, E; Courtin, F; di Rago, JP; Duvezin-Caubet, S; Evrard, J; Fritsch, ES; Funaya, C; Gagneur, J; Kucharczyk, R; Soubigou, F; St Onge, RP; Steinmetz, LM; Suresh, S; van der Laan, M; Voisset, C; von der Malsburg, K, 2014)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Aiyar, RS1
Bohnert, M1
Duvezin-Caubet, S1
Voisset, C1
Gagneur, J1
Fritsch, ES1
Couplan, E1
von der Malsburg, K1
Funaya, C1
Soubigou, F1
Courtin, F1
Suresh, S1
Kucharczyk, R1
Evrard, J1
Antony, C1
St Onge, RP1
Blondel, M1
di Rago, JP1
van der Laan, M1
Steinmetz, LM1

Other Studies

1 other study available for pyrithione and Electron Transport Chain Deficiencies, Mitochondrial

ArticleYear
Mitochondrial protein sorting as a therapeutic target for ATP synthase disorders.
    Nature communications, 2014, Dec-18, Volume: 5

    Topics: Antifungal Agents; Cell Nucleus; Databases, Pharmaceutical; Drug Repositioning; Gene Expression Regu

2014