pyrithione has been researched along with Cancer of Ovary in 2 studies
pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.
Excerpt | Relevance | Reference |
---|---|---|
"Using SKOV3 and ES2 cells, ovarian cancer cell lines that demonstrate varied degrees of resistance to known therapeutics, we show that zinc killing is time and concentration dependent." | 1.37 | Zinc is a potential therapeutic for chemoresistant ovarian cancer. ( Baldassare, J; Bastow, M; Klein, C; Kriedt, CL; Shah, M, 2011) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 1 (50.00) | 2.80 |
Authors | Studies |
---|---|
Chen, M | 1 |
Ding, Y | 1 |
Ke, Y | 1 |
Zeng, Y | 1 |
Liu, N | 1 |
Zhong, Y | 1 |
Hua, X | 1 |
Li, Z | 1 |
Xiong, Y | 1 |
Wu, C | 1 |
Yu, H | 1 |
Bastow, M | 1 |
Kriedt, CL | 1 |
Baldassare, J | 1 |
Shah, M | 1 |
Klein, C | 1 |
2 other studies available for pyrithione and Cancer of Ovary
Article | Year |
---|---|
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Human | 2020 |
Zinc is a potential therapeutic for chemoresistant ovarian cancer.
Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Cycle Checkpoints; Cell Death; | 2011 |