Page last updated: 2024-10-21

pyrithione and Cancer of Ovary

pyrithione has been researched along with Cancer of Ovary in 2 studies

pyrithione: split from cephalosporin molecule; some metal complexes of this have fumarate reductase inhibitory activity and may be useful against trypanosomes; RN given refers to parent cpd; structure
pyrithione : A pyridinethione that is pyridine-2(1H)-thione in which the hydrogen attached to the nitrogen is replaced by a hydroxy group. It is a Zn(2+) ionophore; the zinc salt is used as an antifungal and antibacterial agent.

Research Excerpts

ExcerptRelevanceReference
"Using SKOV3 and ES2 cells, ovarian cancer cell lines that demonstrate varied degrees of resistance to known therapeutics, we show that zinc killing is time and concentration dependent."1.37Zinc is a potential therapeutic for chemoresistant ovarian cancer. ( Baldassare, J; Bastow, M; Klein, C; Kriedt, CL; Shah, M, 2011)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Chen, M1
Ding, Y1
Ke, Y1
Zeng, Y1
Liu, N1
Zhong, Y1
Hua, X1
Li, Z1
Xiong, Y1
Wu, C1
Yu, H1
Bastow, M1
Kriedt, CL1
Baldassare, J1
Shah, M1
Klein, C1

Other Studies

2 other studies available for pyrithione and Cancer of Ovary

ArticleYear
Anti-tumour activity of zinc ionophore pyrithione in human ovarian cancer cells through inhibition of proliferation and migration and promotion of lysosome-mitochondrial apoptosis.
    Artificial cells, nanomedicine, and biotechnology, 2020, Volume: 48, Issue:1

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Female; Human

2020
Zinc is a potential therapeutic for chemoresistant ovarian cancer.
    Journal of experimental therapeutics & oncology, 2011, Volume: 9, Issue:3

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents, Phytogenic; Cell Cycle Checkpoints; Cell Death;

2011