pyrithiamine has been researched along with Disease Models, Animal in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (20.69) | 18.7374 |
| 1990's | 4 (13.79) | 18.2507 |
| 2000's | 8 (27.59) | 29.6817 |
| 2010's | 11 (37.93) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Aghourian, M; Hazell, AS; Oanea, R; Sun, S; Wang, D; Yong, JJ | 1 |
| Hamada, S; Hamaguchi-Hamada, K; Hirashima, H; Imaeda, M; Kurumata-Shigeto, M; Okamoto, Y | 1 |
| Biton, IE; Dror, V; Eliash, S; Rehavi, M | 1 |
| Afadlal, S; Hazell, AS; Labetoulle, R | 1 |
| Bobal, MG; Savage, LM | 1 |
| Hall, JM; Savage, LM | 1 |
| Savage, LM; Vedder, LC | 1 |
| Fan, Z; Ke, ZJ; Li, W; Luo, J; Sun, A; Yang, G; Zhang, Q | 1 |
| Roland, JJ; Savage, LM | 2 |
| Beauchesne, E; Butterworth, RF; Desjardins, P; Hazell, AS | 1 |
| Anzalone, S; Ramos, RL; Savage, LM; Vetreno, RP | 1 |
| Guarino, S; Savage, LM | 1 |
| Klintsova, A; Savage, LM; Vetreno, RP | 1 |
| Pitkin, SR; Savage, LM | 1 |
| Adalsteinsson, E; Bell, RL; Pfefferbaum, A; Sullivan, EV | 1 |
| Klintsova, A; Roland, J; Savage, LM | 1 |
| Aikawa, H; Furuse, T; Iwasaki, Y; Moroji, T; Satoyoshi, E; Sumi, T; Watanabe, IS | 1 |
| Barclay, LL; Gibson, GE | 1 |
| Barke, KE; Hough, LB; Langlais, PJ; Weilersbacher, G; Zhang, SX | 1 |
| Butterworth, RF; Todd, KG | 1 |
| Knitowski, KM; Pitkin, SR; Savage, LM | 1 |
| Nixon, PF; Zimitat, C | 1 |
| Butterworth, RF; Danbolt, NC; Hazell, AS; Pow, DV; Rao, KV | 1 |
| Watanabe, I | 1 |
| Knoth, RL; Langlais, PJ; Mair, RG; Otto, TA; Rabchenuk, SA | 1 |
| Butterworth, RF | 1 |
| Besnard, AM; Butterworth, RF; Giguère, JF | 2 |
2 review(s) available for pyrithiamine and Disease Models, Animal
| Article | Year |
|---|---|
Role of astrocytes in thiamine deficiency.
Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Biological Transport; Blood-Brain Barrier; Brain; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Ketoglutarate Dehydrogenase Complex; Nerve Tissue Proteins; Neurons; Oxidative Stress; Pyrithiamine; Thiamine Deficiency; Wernicke Encephalopathy | 2014 |
Cerebral thiamine-dependent enzyme changes in experimental Wernicke's encephalopathy.
Topics: Animals; Disease Models, Animal; Pyridinium Compounds; Pyrithiamine; Thiamine; Thiamine Deficiency; Wernicke Encephalopathy | 1986 |
27 other study(ies) available for pyrithiamine and Disease Models, Animal
| Article | Year |
|---|---|
Pyrithiamine-induced thiamine deficiency alters proliferation and neurogenesis in both neurogenic and vulnerable areas of the rat brain.
Topics: Animals; Brain; Cell Division; Cells, Cultured; Disease Models, Animal; DNA Replication; Doublecortin Domain Proteins; Doublecortin Protein; Hippocampus; Inferior Colliculi; Lateral Ventricles; Male; Microtubule-Associated Proteins; Neural Stem Cells; Neurogenesis; Neuropeptides; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Wernicke Encephalopathy | 2014 |
Thiamine deficiency induces massive cell death in the olfactory bulbs of mice.
Topics: Animals; Antimetabolites; Calcium-Binding Proteins; Caspase 3; Cell Death; Disease Models, Animal; DNA, Single-Stranded; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred DBA; Microfilament Proteins; Microglia; N-Methylaspartate; Neurons; Olfactory Bulb; Pyrithiamine; Thiamine; Thiamine Deficiency | 2013 |
Rasagiline prevents neurodegeneration in thiamine deficient rats-a longitudinal MRI study.
Topics: Animals; Brain; Diffusion Tensor Imaging; Disease Models, Animal; Disease Progression; Indans; Kaplan-Meier Estimate; Lateral Ventricles; Longitudinal Studies; Magnetic Resonance Imaging; Male; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neuroprotective Agents; Organ Size; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Thiamine Deficiency | 2014 |
The role of ventral midline thalamus in cholinergic-based recovery in the amnestic rat.
Topics: Animal Feed; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Functional Laterality; GABA-A Receptor Agonists; Hippocampus; Korsakoff Syndrome; Male; Maze Learning; Muscimol; Physostigmine; Prefrontal Cortex; Pyrithiamine; Random Allocation; Rats, Sprague-Dawley; Thiamine Deficiency; Ventral Thalamic Nuclei | 2015 |
Exercise leads to the re-emergence of the cholinergic/nestin neuronal phenotype within the medial septum/diagonal band and subsequent rescue of both hippocampal ACh efflux and spatial behavior.
Topics: Acetylcholine; Animals; Antimetabolites; Brain-Derived Neurotrophic Factor; Choline O-Acetyltransferase; Disease Models, Animal; Exercise Therapy; Hippocampus; Male; Motor Activity; Nerve Growth Factor; Nestin; Neurons; Pyrithiamine; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Septum of Brain; Spatial Behavior; Thiamine Deficiency; Time Factors | 2016 |
BDNF regains function in hippocampal long-term potentiation deficits caused by diencephalic damage.
Topics: Animals; Antimetabolites; Brain Injuries; Brain-Derived Neurotrophic Factor; Diencephalon; Disease Models, Animal; Electric Stimulation; Female; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Pyrithiamine; Rats; Thiamine Deficiency | 2017 |
Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides.
Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Antioxidants; Aspartic Acid Endopeptidases; Brain; Cell Death; Cell Line, Tumor; Chromans; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Neuroblastoma; Peptide Fragments; Pyrithiamine; Reactive Oxygen Species; Thiamine; Thiamine Deficiency; Time Factors | 2011 |
The role of cholinergic and GABAergic medial septal/diagonal band cell populations in the emergence of diencephalic amnesia.
Topics: Acetylcholine; Amnesia; Animals; Brain; Calbindins; Cell Death; Choline O-Acetyltransferase; Disease Models, Animal; gamma-Aminobutyric Acid; Korsakoff Syndrome; Male; Neurons; Parvalbumins; Pyrithiamine; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Thalamus; Thiamine Deficiency | 2009 |
eNOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain.
Topics: Animals; Antimetabolites; Blood-Brain Barrier; Disease Models, Animal; Frontal Lobe; Immunoglobulin G; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Nitric Oxide Synthase Type III; Oxidative Stress; Pyrithiamine; Reactive Nitrogen Species; Reactive Oxygen Species; Thalamic Nuclei; Thiamine Deficiency | 2009 |
Cortical cholinergic abnormalities contribute to the amnesic state induced by pyrithiamine-induced thiamine deficiency in the rat.
Topics: Acetylcholine; Acetylcholinesterase; Amnesia; Animals; Cerebral Cortex; Cholinergic Fibers; Disease Models, Animal; Hippocampus; Male; Maze Learning; Microdialysis; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine Deficiency | 2010 |
Memory for reward location is enhanced even though acetylcholine efflux within the amygdala is impaired in rats with damage to the diencephalon produced by thiamine deficiency.
Topics: Acetylcholine; Amnesia; Amygdala; Animals; Antimetabolites; Association Learning; Brain Damage, Chronic; Cholinergic Fibers; Diencephalon; Disease Models, Animal; Male; Maze Learning; Memory; Problem Solving; Pyrithiamine; Random Allocation; Rats; Rats, Sprague-Dawley; Reward; Thiamine Deficiency | 2010 |
Stage-dependent alterations of progenitor cell proliferation and neurogenesis in an animal model of Wernicke-Korsakoff syndrome.
Topics: Animals; Body Weight; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cerebral Ventricles; Disease Models, Animal; Glial Fibrillary Acidic Protein; Korsakoff Syndrome; Male; Microscopy, Confocal; Neurogenesis; Phosphopyruvate Hydratase; Pyrithiamine; Rats; Rats, Sprague-Dawley; Stem Cells; Thiamine Deficiency | 2011 |
Age-related vulnerability to diencephalic amnesia produced by thiamine deficiency: the role of time of insult.
Topics: Aging; Amnesia; Animals; Antimetabolites; Behavior, Animal; Body Weight; Brain Mapping; Cell Count; Cerebral Ventricles; Choline O-Acetyltransferase; Diet; Discrimination Learning; Disease Models, Animal; Immunohistochemistry; Korsakoff Syndrome; Male; Maze Learning; Memory, Short-Term; Prosencephalon; Pyrithiamine; Rats; Rats, Inbred F344; Spatial Behavior; Thiamine; Thiamine Deficiency; Time Factors | 2004 |
Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study.
Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Antimetabolites; Biomarkers; Brain; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Korsakoff Syndrome; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Pyrithiamine; Rats; Rats, Wistar; Survival Rate; Thiamine; Thiamine Deficiency | 2007 |
Blunted hippocampal, but not striatal, acetylcholine efflux parallels learning impairment in diencephalic-lesioned rats.
Topics: Acetylcholine; Animals; Diencephalon; Disease Models, Animal; Exploratory Behavior; Hippocampus; Korsakoff Syndrome; Learning Disabilities; Male; Maze Learning; Microdialysis; Neostriatum; Organ Size; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Thiamine Deficiency | 2007 |
Selective septohippocampal - but not forebrain amygdalar - cholinergic dysfunction in diencephalic amnesia.
Topics: Acetylcholine; Amnesia; Amygdala; Analysis of Variance; Animals; Choline O-Acetyltransferase; Cholinergic Fibers; Discrimination Learning; Disease Models, Animal; Exploratory Behavior; Hippocampus; Male; Neural Pathways; Pyrithiamine; Rats; Rats, Sprague-Dawley; Septum of Brain; Thiamine Deficiency | 2007 |
Low energy levels in thiamine-deficient encephalopathy.
Topics: Animals; Behavior, Animal; Brain; Brain Diseases; Disease Models, Animal; Energy Metabolism; Male; Microscopy, Electron; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency | 1984 |
Spontaneous open-field behavior in thiamin-deficient rats.
Topics: Animals; Behavior, Animal; Disease Models, Animal; Grooming; Male; Movement; Oxythiamine; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency | 1982 |
Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy.
Topics: Animals; Cell Death; Disease Models, Animal; Gliosis; Glutamic Acid; Glutamine; Hippocampus; Histamine; Histamine Release; Male; Methylhistidines; Microdialysis; Necrosis; Nerve Degeneration; Neuroglia; Pyrithiamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy | 1994 |
Increased neuronal cell survival after L-deprenyl treatment in experimental thiamine deficiency.
Topics: Animals; Behavior, Animal; Cell Count; Cell Survival; Disease Models, Animal; Drug Administration Schedule; Immunohistochemistry; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Neurons; Pyrithiamine; Rats; Rats, Sprague-Dawley; Selegiline; Thiamine Deficiency | 1998 |
Rats exposed to acute pyrithiamine-induced thiamine deficiency are more sensitive to the amnestic effects of scopolamine and MK-801: examination of working memory, response selection, and reinforcement contingencies.
Topics: Acute Disease; Amnesia; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Korsakoff Syndrome; Male; Memory, Short-Term; Pyrithiamine; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Thalamus; Thiamine Deficiency | 1999 |
Glucose induced IEG expression in the thiamin-deficient rat brain.
Topics: Animals; Antimetabolites; Brain; Disease Models, Animal; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Glucose; Humans; Organ Specificity; Pyrithiamine; Rats; Rats, Wistar; Thiamine Deficiency; Wernicke Encephalopathy | 2001 |
Selective down-regulation of the astrocyte glutamate transporters GLT-1 and GLAST within the medial thalamus in experimental Wernicke's encephalopathy.
Topics: Amino Acid Transport System X-AG; Animals; Antimetabolites; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Disease Models, Animal; Down-Regulation; Glutamic Acid; Humans; Immunoblotting; Immunohistochemistry; Intermediate Filament Proteins; Male; Parietal Lobe; Pyrithiamine; Rats; Rats, Sprague-Dawley; Statistics as Topic; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy | 2001 |
Pyrithiamine-induced acute thiamine-deficient encephalopathy in the mouse.
Topics: Animals; Astrocytes; Brain Edema; Cerebral Hemorrhage; Disease Models, Animal; Male; Mice; Microscopy, Electron; Pyridinium Compounds; Pyrithiamine; Wernicke Encephalopathy | 1978 |
Analysis of aversively conditioned learning and memory in rats recovered from pyrithiamine-induced thiamine deficiency.
Topics: Alcohol Amnestic Disorder; Analysis of Variance; Animals; Avoidance Learning; Discrimination Learning; Disease Models, Animal; Electroshock; Escape Reaction; Gliosis; Male; Mammillary Bodies; Memory; Models, Neurological; Pyrithiamine; Rats; Thalamus; Thiamine; Thiamine Deficiency; Visual Perception | 1991 |
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy. 2. alpha-Ketoglutarate dehydrogenase.
Topics: Animals; Brain; Diet; Disease Models, Animal; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Male; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Time Factors; Wernicke Encephalopathy | 1986 |
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy: 1. The pyruvate dehydrogenase complex.
Topics: Animals; Brain Diseases, Metabolic; Brain Stem; Disease Models, Animal; Male; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Reflex; Thiamine; Thiamine Deficiency; Transketolase | 1985 |