Page last updated: 2024-08-21

pyrithiamine and Deficiency, Thiamine

pyrithiamine has been researched along with Deficiency, Thiamine in 114 studies

Research

Studies (114)

Timeframe	Studies, this research(%)	All Research%
pre-1990	46 (40.35)	18.7374
1990's	27 (23.68)	18.2507
2000's	21 (18.42)	29.6817
2010's	17 (14.91)	24.3611
2020's	3 (2.63)	2.80

Authors

Authors	Studies
Blecharz-Klin, K; Joniec-Maciejak, I; Krzysztoforska, K; Krzysztoforski, J; Piechal, A; Pyrzanowska, J; Widy-Tyszkiewicz, E; Wojnar, E	1
Aguiar, HQDS; de Cordova, CAS; de Cordova, FM; Medeiros, RCN; Moraes, JO; Pereira, LM; Rodrigues, SDC; Yim Júnior, A	1
Kipp, BT; Nunes, PT; Savage, LM	1
Bowyer, JF; Hanig, JP; Sarkar, S; Tranter, KM	1
Deak, T; Savage, LM; Toledo Nunes, P; Vedder, LC	1
Hall, JM; Savage, LM; Vetreno, RP	1
Hamada, S; Hamaguchi-Hamada, K; Hirashima, H; Imaeda, M; Kurumata-Shigeto, M; Okamoto, Y	1
Biton, IE; Dror, V; Eliash, S; Rehavi, M	1
Afadlal, S; Hazell, AS; Labetoulle, R	1
Bobal, MG; Savage, LM	1
Hall, JM; Savage, LM	1
Hasegawa, S; Inaba, H; Kida, S; Kishimoto, T; Nagata, K; Oishi, S; Watanabe, T	1
Savage, LM; Vedder, LC	1
Mark, K; Roland, JJ; Savage, LM; Vetreno, RP	1
Fan, Z; Ke, ZJ; Li, W; Luo, J; Sun, A; Yang, G; Zhang, Q	1
Roland, JJ; Savage, LM	2
Beauchesne, E; Butterworth, RF; Desjardins, P; Hazell, AS	1
Ferreira, LF; Oliveira-Silva, Ide F; Pereira, SR; Ribeiro, AM; Vigil, FA	1
Bielarczyk, H; Jankowska-Kulawy, A; Pawełczyk, T; Szutowicz, A; Wróblewska, M	1
Anzalone, S; Ramos, RL; Savage, LM; Vetreno, RP	1
Guarino, S; Savage, LM	1
Klintsova, A; Savage, LM; Vetreno, RP	1
Savage, LM	1
Akerman, G; Amcoff, P; Balk, L; Börjeson, H; Norrgren, L; Tjärnlund, U	1
Hough, LB; Langlais, PJ; McRee, RC; Nalwalk, JA	1
Meng, JS; Okeda, R	1
Hazell, AS; Pannunzio, P; Pow, DV; Rama Rao, KV; Rambaldi, A	1
KOEDAM, JC; STEYN-PARVE, EP; VAN RHEENEN, DL	1
KOEDAM, JC	1
DE CARO, L; FERRARI, G; PERRI, V; RINDI, G	1
FERRARI, V	1
CAPPELLI, V; CERIANI, T; GRANA, E	1
Jones, JH	1
GIACALONE, E; VENTURA, U	1
Pitkin, SR; Savage, LM	2
Butterworth, RF; Chan, H; Hazell, AS	1
Little, HJ; Littleton, JM; Mulholland, PJ; Prendergast, MA; Self, RL; Stepanyan, TD	1
Mulholland, PJ	1
Adalsteinsson, E; Bell, RL; Pfefferbaum, A; Sullivan, EV	1
Klintsova, A; Roland, J; Savage, LM	1
Harper, CG; He, X; Pfefferbaum, A; Stankovic, RK; Sullivan, EV	1
Chorna, N; Chornyy, S; Parkhomenko, J	1
Butterworth, RF; Navarro, D; Zwingmann, C	1
Berl, S; Hwang, EC; Plaitakis, A; Szilagyi, PE; Woert, MH	1
Horita, N; Izumiyama, Y; Okuno, A	1
Carpenter, S; Hakim, AM; Pappius, HM	1
Aikawa, H; Furuse, T; Iwasaki, Y; Moroji, T; Satoyoshi, E; Sumi, T; Watanabe, IS	1
Brosemer, RW; Gale, JM	1
McCandless, DW	1
Barclay, L; Blass, J; Gibson, G	1
Barclay, LL; Gibson, GE	1
Barclay, LL; Blass, JP; Gibson, GE	3
Irle, E; Markowitsch, HJ	1
Oguchi, E; Sakamoto, K	1
Aikawa, H	1
Hajikano, M; Hobara, R; Kato, H; Oguchi, E; Okazaki, M; Sakamoto, K	1
Noumi, M; Oguchi, E; Okazaki, M; Sakamoto, K	1
Hobara, R; Okazaki, M; Sakamoto, K; Yasuhara, H	1
Pekkanen, L	1
Barke, KE; Hough, LB; Langlais, PJ; Weilersbacher, G; Zhang, SX	1
Langlais, PJ; Savage, LM	1
Harata, N; Iwasaki, Y	1
Corso, T; Henderson, SW; Langlais, PJ; Olney, JW; Weilersbacher, GS; Zhang, SX	1
Langlais, PJ; Zhang, SX	1
Butterworth, RF; Mousseau, DD; Rao, VL	4
Martin, PR; Pekovich, SR; Singleton, CK	1
Beleta, J; Coll-Cantí, J; Gella, FJ; González-Sastre, F; Munujos, P	1
Abbott, NJ; Aleshaiker, A; Rist, RJ; Romero, IA	1
Anderson, G; Bondy, SC; Guo, SX; Langlais, PJ	1
Chen, Q; Okada, S; Okeda, R	1
Butterworth, RF; Todd, KG	1
Fushiki, S; Kawata, M; Kosaka, K; Matsushita, H; Sawada, T; Takeuchi, Y	1
Butterworth, RF; Todd, K	1
Butterworth, RF; Hazell, AS; Pannunzio, M; Pannunzio, P; Rao, KV	1
Knitowski, KM; Pitkin, SR; Savage, LM	1
Nixon, PF; Zimitat, C	1
Butterworth, RF; Danbolt, NC; Hazell, AS; Pow, DV; Rao, KV	1
Berl, S; Nicklas, WJ; Plaitakis, A	1
Cooper, JR; Pincus, JH	1
Barbeau, A; Jolicoeur, FB; Rondeau, DB; Wayner, MJ	1
Barbeau, A; Butterworth, RF; Hamel, E; Jolicoeur, FB; Rondeau, DB	1
Barbeau, A; Butterworth, RF; Hamel, E; Landreville, F	1
Berl, S; Hwang, EC; Plaitakis, A; Van Woert, MH	2
Oguchi, E; Okazaki, M; Sakamoto, K; Yasuhara, H	1
Koeppe, RE; Meghal, SK; O'Neal, RM	1
Hobara, R; Oguchi, E; Okazaki, M; Sakamoto, K; Toyoshima, Y	1
Gubler, CJ	1
Mair, RG; Robinson, JK	1
Lacourse, DM; Mair, RG	1
Butterworth, RF; Héroux, M; Lê, O	1
Inomata, K; Tomiyasu, K	1
Knoth, RL; Langlais, PJ; Mair, RG; Otto, TA; Rabchenuk, SA	1
Knoth, RL; Langlais, PJ; Mair, RG; Rabchenuk, SA	1
Knoth, RL; Mair, RG	1
Langlais, PJ; Mair, RG	1
Oguchi, K; Ohtsuki, A; Okazaki, M; Sakamoto, H	1
Butterworth, RF; Héroux, M	1
Elnageh, KM; Gaitonde, MK	1
Anderson, CD; Langlais, PJ; Mair, RG; McEntee, WJ	1
Butterworth, RF	1
Nakazawa, S; Shimura, T; Takahashi, H; Yoshino, Y	1
Butterworth, RF; Giguère, JF	1
Le Roch, K; Riche, D; Sara, SJ	1
Comly, M; Levin, SW; Mukherjee, AB; Roecklein, B	1
Besnard, AM; Butterworth, RF; Giguere, JF	1
McGeer, EG; Thompson, SG	1

Reviews

4 review(s) available for pyrithiamine and Deficiency, Thiamine

Article	Year
Role of astrocytes in thiamine deficiency. Metabolic brain disease, 2014, Volume: 29, Issue:4 Topics: Amino Acid Transport System X-AG; Animals; Astrocytes; Biological Transport; Blood-Brain Barrier; Brain; Disease Models, Animal; Excitatory Amino Acid Transporter 2; Glutamic Acid; Humans; Ketoglutarate Dehydrogenase Complex; Nerve Tissue Proteins; Neurons; Oxidative Stress; Pyrithiamine; Thiamine Deficiency; Wernicke Encephalopathy	2014
Susceptibility of the cerebellum to thiamine deficiency. Cerebellum (London, England), 2006, Volume: 5, Issue:1 Topics: Acetaldehyde; Animals; Cerebellum; Disease Susceptibility; Dizocilpine Maleate; Drug Interactions; Gait Ataxia; Humans; Neurons; Pyrithiamine; Thiamine Deficiency	2006
The role of the cholinergic system in thiamin deficiency. Annals of the New York Academy of Sciences, 1982, Volume: 378 Topics: Acetyl Coenzyme A; Acetylcholine; Aging; Animals; Arecoline; Atropine; Behavior, Animal; Brain; Diet; Electrophysiology; Ganglia, Sympathetic; Humans; Male; Oxythiamine; Parasympathetic Nervous System; Physostigmine; Pyrithiamine; Pyruvates; Pyruvic Acid; Rats; Synapses; Thiamine Deficiency; Tissue Distribution	1982
Cerebral thiamine-dependent enzyme changes in experimental Wernicke's encephalopathy. Metabolic brain disease, 1986, Volume: 1, Issue:3 Topics: Animals; Disease Models, Animal; Pyridinium Compounds; Pyrithiamine; Thiamine; Thiamine Deficiency; Wernicke Encephalopathy	1986

Other Studies

110 other study(ies) available for pyrithiamine and Deficiency, Thiamine

Article	Year
Protocatechuic Acid Prevents Some of the Memory-Related Behavioural and Neurotransmitter Changes in a Pyrithiamine-Induced Thiamine Deficiency Model of Wernicke-Korsakoff Syndrome in Rats. Nutrients, 2023, Jan-26, Volume: 15, Issue:3 Topics: Animals; Korsakoff Syndrome; Neurotransmitter Agents; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency	2023
Thiamine Deficiency Modulates p38 Neurochemical research, 2020, Volume: 45, Issue:4 Topics: Animals; Behavior, Animal; Body Weight; Brain; Cell Survival; Chromans; Dimethyl Sulfoxide; Eating; Heme Oxygenase-1; Inflammation; Male; Membrane Proteins; Mice; Neuroprotective Agents; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrithiamine; Thiamine Deficiency	2020
Sex differences in cholinergic circuits and behavioral disruptions following chronic ethanol exposure with and without thiamine deficiency. Alcoholism, clinical and experimental research, 2021, Volume: 45, Issue:5 Topics: Acetylcholine; Alcoholism; Animals; Antimetabolites; Attention; Behavior, Animal; Case-Control Studies; Central Nervous System Depressants; Ethanol; Female; Hippocampus; Male; Microdialysis; Prefrontal Cortex; Pyrithiamine; Rats; Sex Factors; Thiamine Deficiency	2021
Microglial activation and vascular responses that are associated with early thalamic neurodegeneration resulting from thiamine deficiency. Neurotoxicology, 2018, Volume: 65 Topics: Animals; Blood Vessels; Calcium-Binding Proteins; CD11b Antigen; Diet; Dizocilpine Maleate; Female; Mice; Microfilament Proteins; Microglia; Nerve Degeneration; Phenobarbital; Pyrithiamine; Thalamus; Thiamine Deficiency; Time Factors	2018
A Pivotal Role for Thiamine Deficiency in the Expression of Neuroinflammation Markers in Models of Alcohol-Related Brain Damage. Alcoholism, clinical and experimental research, 2019, Volume: 43, Issue:3 Topics: Animals; Biomarkers; Brain; Ethanol; Frontal Lobe; Hippocampus; Inflammation Mediators; Male; Pyrithiamine; Rats; Thalamus; Thiamine; Thiamine Deficiency; Time Factors; Transcriptional Activation	2019
Differential cortical neurotrophin and cytogenetic adaptation after voluntary exercise in normal and amnestic rats. Neuroscience, 2014, Jan-31, Volume: 258 Topics: Amnesia; Animals; Brain-Derived Neurotrophic Factor; Cell Survival; Cerebral Cortex; Cytogenetic Analysis; Frontal Lobe; Housing, Animal; Male; Motor Activity; Nerve Growth Factor; Nerve Growth Factors; Occipital Lobe; Oligodendroglia; Pyrithiamine; Rats; Rats, Sprague-Dawley; Stem Cells; Thiamine Deficiency; Time Factors; Vascular Endothelial Growth Factor A	2014
Thiamine deficiency induces massive cell death in the olfactory bulbs of mice. Journal of neuropathology and experimental neurology, 2013, Volume: 72, Issue:12 Topics: Animals; Antimetabolites; Calcium-Binding Proteins; Caspase 3; Cell Death; Disease Models, Animal; DNA, Single-Stranded; In Situ Nick-End Labeling; Male; Mice; Mice, Inbred DBA; Microfilament Proteins; Microglia; N-Methylaspartate; Neurons; Olfactory Bulb; Pyrithiamine; Thiamine; Thiamine Deficiency	2013
Rasagiline prevents neurodegeneration in thiamine deficient rats-a longitudinal MRI study. Brain research, 2014, Apr-04, Volume: 1557 Topics: Animals; Brain; Diffusion Tensor Imaging; Disease Models, Animal; Disease Progression; Indans; Kaplan-Meier Estimate; Lateral Ventricles; Longitudinal Studies; Magnetic Resonance Imaging; Male; Monoamine Oxidase Inhibitors; Nerve Degeneration; Neuroprotective Agents; Organ Size; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Thiamine Deficiency	2014
The role of ventral midline thalamus in cholinergic-based recovery in the amnestic rat. Neuroscience, 2015, Jan-29, Volume: 285 Topics: Animal Feed; Animals; Cholinesterase Inhibitors; Disease Models, Animal; Functional Laterality; GABA-A Receptor Agonists; Hippocampus; Korsakoff Syndrome; Male; Maze Learning; Muscimol; Physostigmine; Prefrontal Cortex; Pyrithiamine; Random Allocation; Rats, Sprague-Dawley; Thiamine Deficiency; Ventral Thalamic Nuclei	2015
Exercise leads to the re-emergence of the cholinergic/nestin neuronal phenotype within the medial septum/diagonal band and subsequent rescue of both hippocampal ACh efflux and spatial behavior. Experimental neurology, 2016, Volume: 278 Topics: Acetylcholine; Animals; Antimetabolites; Brain-Derived Neurotrophic Factor; Choline O-Acetyltransferase; Disease Models, Animal; Exercise Therapy; Hippocampus; Male; Motor Activity; Nerve Growth Factor; Nestin; Neurons; Pyrithiamine; Rats; Rats, Sprague-Dawley; Recognition, Psychology; Septum of Brain; Spatial Behavior; Thiamine Deficiency; Time Factors	2016
Vitamin B1-deficient mice show impairment of hippocampus-dependent memory formation and loss of hippocampal neurons and dendritic spines: potential microendophenotypes of Wernicke-Korsakoff syndrome. Bioscience, biotechnology, and biochemistry, 2016, Volume: 80, Issue:12 Topics: Amygdala; Animals; Ataxia; Body Weight; Dendritic Spines; Hippocampus; Korsakoff Syndrome; Memory; Mice; Phenotype; Pyrithiamine; Thiamine Deficiency	2016
BDNF regains function in hippocampal long-term potentiation deficits caused by diencephalic damage. Learning & memory (Cold Spring Harbor, N.Y.), 2017, Volume: 24, Issue:2 Topics: Animals; Antimetabolites; Brain Injuries; Brain-Derived Neurotrophic Factor; Diencephalon; Disease Models, Animal; Electric Stimulation; Female; Hippocampus; Long-Term Potentiation; Male; Maze Learning; Pyrithiamine; Rats; Thiamine Deficiency	2017
Increasing hippocampal acetylcholine levels enhance behavioral performance in an animal model of diencephalic amnesia. Brain research, 2008, Oct-09, Volume: 1234 Topics: Acetylcholine; Amnesia; Animals; Antimetabolites; Behavior, Animal; Cholinesterase Inhibitors; Chromatography, High Pressure Liquid; Cognition; Diencephalon; Hippocampus; Immunohistochemistry; Korsakoff Syndrome; Male; Microdialysis; Physostigmine; Psychomotor Performance; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine Deficiency	2008
Thiamine deficiency increases β-secretase activity and accumulation of β-amyloid peptides. Neurobiology of aging, 2011, Volume: 32, Issue:1 Topics: Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Amyloid Precursor Protein Secretases; Analysis of Variance; Animals; Antioxidants; Aspartic Acid Endopeptidases; Brain; Cell Death; Cell Line, Tumor; Chromans; Disease Models, Animal; Gene Expression Regulation; Humans; Male; Mice; Mice, Inbred C57BL; Neuroblastoma; Peptide Fragments; Pyrithiamine; Reactive Oxygen Species; Thiamine; Thiamine Deficiency; Time Factors	2011
The role of cholinergic and GABAergic medial septal/diagonal band cell populations in the emergence of diencephalic amnesia. Neuroscience, 2009, Apr-21, Volume: 160, Issue:1 Topics: Acetylcholine; Amnesia; Animals; Brain; Calbindins; Cell Death; Choline O-Acetyltransferase; Disease Models, Animal; gamma-Aminobutyric Acid; Korsakoff Syndrome; Male; Neurons; Parvalbumins; Pyrithiamine; Rats; Rats, Sprague-Dawley; S100 Calcium Binding Protein G; Thalamus; Thiamine Deficiency	2009
eNOS gene deletion restores blood-brain barrier integrity and attenuates neurodegeneration in the thiamine-deficient mouse brain. Journal of neurochemistry, 2009, Volume: 111, Issue:2 Topics: Animals; Antimetabolites; Blood-Brain Barrier; Disease Models, Animal; Frontal Lobe; Immunoglobulin G; Male; Matrix Metalloproteinase 9; Mice; Mice, Inbred C57BL; Mice, Knockout; Nerve Degeneration; Nitric Oxide Synthase Type III; Oxidative Stress; Pyrithiamine; Reactive Nitrogen Species; Reactive Oxygen Species; Thalamic Nuclei; Thiamine Deficiency	2009
Spatial memory deficits and thalamic serotonergic metabolite change in thiamine deficient rats. Behavioural brain research, 2010, Jun-26, Volume: 210, Issue:1 Topics: Analysis of Variance; Animals; Hydroxyindoleacetic Acid; Male; Maze Learning; Memory Disorders; Neuropsychological Tests; Pyrithiamine; Rats; Rats, Wistar; Serotonin; Space Perception; Thalamus; Thiamine Deficiency; Time Factors	2010
Acetyl-CoA and acetylcholine metabolism in nerve terminal compartment of thiamine deficient rat brain. Journal of neurochemistry, 2010, Volume: 115, Issue:2 Topics: Acetyl Coenzyme A; Acetylcholine; Animals; Brain; Citric Acid; Ketoglutarate Dehydrogenase Complex; Ketoglutaric Acids; Ketone Oxidoreductases; Lactic Acid; Male; Models, Biological; Nerve Endings; Pyrithiamine; Pyruvic Acid; Rats; Rats, Wistar; Synaptosomes; Thiamine Deficiency	2010
Cortical cholinergic abnormalities contribute to the amnesic state induced by pyrithiamine-induced thiamine deficiency in the rat. The European journal of neuroscience, 2010, Volume: 32, Issue:5 Topics: Acetylcholine; Acetylcholinesterase; Amnesia; Animals; Cerebral Cortex; Cholinergic Fibers; Disease Models, Animal; Hippocampus; Male; Maze Learning; Microdialysis; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine Deficiency	2010
Memory for reward location is enhanced even though acetylcholine efflux within the amygdala is impaired in rats with damage to the diencephalon produced by thiamine deficiency. Neurobiology of learning and memory, 2010, Volume: 94, Issue:4 Topics: Acetylcholine; Amnesia; Amygdala; Animals; Antimetabolites; Association Learning; Brain Damage, Chronic; Cholinergic Fibers; Diencephalon; Disease Models, Animal; Male; Maze Learning; Memory; Problem Solving; Pyrithiamine; Random Allocation; Rats; Rats, Sprague-Dawley; Reward; Thiamine Deficiency	2010
Stage-dependent alterations of progenitor cell proliferation and neurogenesis in an animal model of Wernicke-Korsakoff syndrome. Brain research, 2011, May-19, Volume: 1391 Topics: Animals; Body Weight; Bromodeoxyuridine; Cell Count; Cell Proliferation; Cerebral Ventricles; Disease Models, Animal; Glial Fibrillary Acidic Protein; Korsakoff Syndrome; Male; Microscopy, Confocal; Neurogenesis; Phosphopyruvate Hydratase; Pyrithiamine; Rats; Rats, Sprague-Dawley; Stem Cells; Thiamine Deficiency	2011
Sustaining high acetylcholine levels in the frontal cortex, but not retrosplenial cortex, recovers spatial memory performance in a rodent model of diencephalic amnesia. Behavioral neuroscience, 2012, Volume: 126, Issue:2 Topics: Acetylcholine; Animals; Cerebral Cortex; Frontal Lobe; Gyrus Cinguli; Hippocampus; Korsakoff Syndrome; Maze Learning; Microdialysis; Models, Animal; Physostigmine; Pyrithiamine; Rats; Thalamus; Thiamine Deficiency	2012
Physiological, biochemical and morphological studies of Baltic salmon yolk-sac fry with an experimental thiamine deficiency: relations to the M74 syndrome. Aquatic toxicology (Amsterdam, Netherlands), 2002, Nov-13, Volume: 61, Issue:1-2 Topics: Animals; Antimetabolites; Cytochrome P-450 CYP1A1; Embryo, Nonmammalian; Liver; Mortality; Pyrithiamine; Salmo salar; Syndrome; Thiamine Deficiency; Yolk Sac	2002
Depletion of brain histamine produces regionally selective protection against thiamine deficiency-induced lesions in the rat. Metabolic brain disease, 2002, Volume: 17, Issue:3 Topics: Animals; Antimetabolites; Behavior, Animal; Brain Chemistry; Enzyme Inhibitors; Histamine; Histidine Decarboxylase; Hypothalamic Area, Lateral; Injections, Intraventricular; Male; Methylhistidines; Neurotoxicity Syndromes; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamic Nuclei; Thalamus; Thiamine Deficiency	2002
Neuropathological study of the role of mast cells and histamine-positive neurons in selective vulnerability of the thalamus and inferior colliculus in thiamine-deficient encephalopathy. Neuropathology : official journal of the Japanese Society of Neuropathology, 2003, Volume: 23, Issue:1 Topics: Animals; Antimetabolites; Blood-Brain Barrier; Brain Diseases, Metabolic; Histamine; Immunohistochemistry; Inferior Colliculi; Male; Mast Cells; Models, Animal; Neurons; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Thiamine; Thiamine Deficiency	2003
Thiamine deficiency results in downregulation of the GLAST glutamate transporter in cultured astrocytes. Glia, 2003, Volume: 43, Issue:2 Topics: Acid Anhydride Hydrolases; alpha-Tocopherol; Amino Acid Transport System X-AG; Animals; Animals, Newborn; Astrocytes; Cell Size; Cells, Cultured; D-Aspartic Acid; Drug Interactions; Enzyme Inhibitors; Glutathione; Immunoblotting; Ketoglutarate Dehydrogenase Complex; Leucine; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Sodium-Potassium-Exchanging ATPase; Thiamine; Thiamine Deficiency; Time Factors; Transketolase; Tritium	2003
Thiamine deficiency after feeding pyrithiamine. Biochimica et biophysica acta, 1956, Volume: 19, Issue:1 Topics: Humans; Pyridines; Pyrithiamine; Thiamine; Thiamine Deficiency; Vitamin B Deficiency	1956
The mode of action of pyrithiamine as an inductor of thiamine deficiency. Biochimica et biophysica acta, 1958, Volume: 29, Issue:2 Topics: Pyrithiamine; Thiamine; Thiamine Deficiency	1958
[Vitamin B1 deficiency induced by dietary means and by vitamin antagonists (neopyrithiamine and oxythiamine) in rodents]. Internationale Zeitschrift fur Vitaminforschung. Beiheft, 1958, Volume: 28, Issue:3 Topics: Diet; Oxythiamine; Pyrithiamine; Thiamine; Thiamine Deficiency; Vitamin B Deficiency; Vitamins	1958
Changes in tissue free aminoacids in thiamine-deficient or pyrithiamine-treated rats. Acta vitaminologica, 1958, Volume: 12, Issue:4 Topics: Amino Acids; Animals; Biochemical Phenomena; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Vitamin B Deficiency	1958
[Behavior of the adrenal in B1 avitaminosis due to neopyrithiamine]. Bollettino della Societa italiana di biologia sperimentale, 1960, Mar-31, Volume: 36 Topics: Adrenal Glands; Avitaminosis; Pyrithiamine; Thiamine; Thiamine Deficiency; Vitamin B Deficiency	1960
A striking difference in the thiamine-sparing action of fat on deficiencies produced by oxythiamine and pyrithiamine. The Journal of nutrition, 1962, Volume: 78, Issue:3 Topics: Fats; Glycerol; Humans; Oxythiamine; Pyrithiamine; Thiamine; Thiamine Deficiency	1962
[PHOSPHATASE ACTIVITY OF SOME RAT TISSUES IN ALIMENTARY AVITAMINOSIS B1 AND AFTER TREATMENT WITH PYRITHIAMINE]. Internationale Zeitschrift fur Vitaminforschung. International journal of vitamin research. Journal international de vitaminologie, 1963, Volume: 33 Topics: Brain; Liver; Metabolism; Muscles; Pharmacology; Phosphoric Monoester Hydrolases; Pyrithiamine; Rats; Research; Thiamine; Thiamine Deficiency; Transferases	1963
Age-related vulnerability to diencephalic amnesia produced by thiamine deficiency: the role of time of insult. Behavioural brain research, 2004, Jan-05, Volume: 148, Issue:1-2 Topics: Aging; Amnesia; Animals; Antimetabolites; Behavior, Animal; Body Weight; Brain Mapping; Cell Count; Cerebral Ventricles; Choline O-Acetyltransferase; Diet; Discrimination Learning; Disease Models, Animal; Immunohistochemistry; Korsakoff Syndrome; Male; Maze Learning; Memory, Short-Term; Prosencephalon; Pyrithiamine; Rats; Rats, Inbred F344; Spatial Behavior; Thiamine; Thiamine Deficiency; Time Factors	2004
Primary cultures of rat astrocytes respond to thiamine deficiency-induced swelling by downregulating aquaporin-4 levels. Neuroscience letters, 2004, Aug-19, Volume: 366, Issue:3 Topics: 3-O-Methylglucose; Animals; Animals, Newborn; Aquaporin 4; Aquaporins; Astrocytes; Blotting, Western; Cells, Cultured; Cerebral Cortex; Dose-Response Relationship, Drug; Down-Regulation; Edema; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine; Thiamine Deficiency; Time Factors	2004
Thiamine deficiency in the pathogenesis of chronic ethanol-associated cerebellar damage in vitro. Neuroscience, 2005, Volume: 135, Issue:4 Topics: Animals; Central Nervous System Depressants; Cerebellum; Ethanol; Female; Male; Organ Culture Techniques; Pyrithiamine; Rats; Rats, Sprague-Dawley; Substance Withdrawal Syndrome; Thiamine Deficiency	2005
Development and resolution of brain lesions caused by pyrithiamine- and dietary-induced thiamine deficiency and alcohol exposure in the alcohol-preferring rat: a longitudinal magnetic resonance imaging and spectroscopy study. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:5 Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Antimetabolites; Biomarkers; Brain; Central Nervous System Depressants; Disease Models, Animal; Ethanol; Korsakoff Syndrome; Longitudinal Studies; Magnetic Resonance Imaging; Magnetic Resonance Spectroscopy; Male; Nerve Degeneration; Pyrithiamine; Rats; Rats, Wistar; Survival Rate; Thiamine; Thiamine Deficiency	2007
Blunted hippocampal, but not striatal, acetylcholine efflux parallels learning impairment in diencephalic-lesioned rats. Neurobiology of learning and memory, 2007, Volume: 87, Issue:1 Topics: Acetylcholine; Animals; Diencephalon; Disease Models, Animal; Exploratory Behavior; Hippocampus; Korsakoff Syndrome; Learning Disabilities; Male; Maze Learning; Microdialysis; Neostriatum; Organ Size; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thalamus; Thiamine Deficiency	2007
Selective septohippocampal - but not forebrain amygdalar - cholinergic dysfunction in diencephalic amnesia. Brain research, 2007, Mar-30, Volume: 1139 Topics: Acetylcholine; Amnesia; Amygdala; Analysis of Variance; Animals; Choline O-Acetyltransferase; Cholinergic Fibers; Discrimination Learning; Disease Models, Animal; Exploratory Behavior; Hippocampus; Male; Neural Pathways; Pyrithiamine; Rats; Rats, Sprague-Dawley; Septum of Brain; Thiamine Deficiency	2007
Interaction of thiamine deficiency and voluntary alcohol consumption disrupts rat corpus callosum ultrastructure. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2007, Volume: 32, Issue:10 Topics: Alcohol-Induced Disorders, Nervous System; Alcoholism; Animals; Antimetabolites; Atrophy; Central Nervous System Depressants; Corpus Callosum; Ethanol; Nerve Fibers, Myelinated; Pyrithiamine; Rats; Rats, Mutant Strains; Rats, Wistar; Thiamine Deficiency; Wallerian Degeneration	2007
Thiamine deficiency caused by thiamine antagonists triggers upregulation of apoptosis inducing factor gene expression and leads to caspase 3-mediated apoptosis in neuronally differentiated rat PC-12 cells. Acta biochimica Polonica, 2007, Volume: 54, Issue:2 Topics: Active Transport, Cell Nucleus; Amprolium; Animals; Annexin A5; Apoptosis; Apoptosis Inducing Factor; Caspase 3; Cell Differentiation; Cell Membrane; Nerve Growth Factor; Neurons; Oxythiamine; PC12 Cells; Protein Binding; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Up-Regulation	2007
Region-selective alterations of glucose oxidation and amino acid synthesis in the thiamine-deficient rat brain: a re-evaluation using 1H/13C nuclear magnetic resonance spectroscopy. Journal of neurochemistry, 2008, Volume: 106, Issue:2 Topics: Amino Acids; Animals; Brain; Brain Chemistry; Carbon Isotopes; Citric Acid Cycle; Glucose; Magnetic Resonance Spectroscopy; Male; Oxidation-Reduction; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine Deficiency; Tritium	2008
Effect of thiamin deficiency on brain neurotransmitter systems. Annals of the New York Academy of Sciences, 1982, Volume: 378 Topics: Acetylcholine; Animals; Aspartic Acid; Brain; Diet; Glutamates; Glutamic Acid; Guanosine Monophosphate; Hydroxyindoleacetic Acid; Male; Neurotransmitter Agents; Pyrithiamine; Rats; Rats, Inbred Strains; Serotonin; Synaptosomes; Thiamine Deficiency; Tissue Distribution	1982
Neuropathologic changes in suckling and weanling rats with pyrithiamine-induced thiamine deficiency. Acta neuropathologica, 1983, Volume: 61, Issue:1 Topics: Age Factors; Animals; Axons; Brain; Cerebellum; Dendrites; Mammillary Bodies; Microscopy, Electron; Pyrithiamine; Rats; Thalamus; Thiamine Deficiency; Vestibular Nuclei	1983
Metabolic and histological reversibility of thiamine deficiency. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 1983, Volume: 3, Issue:4 Topics: Animals; Autoradiography; Body Weight; Brain; Diet; Glucose; Male; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency; Time Factors	1983
Low energy levels in thiamine-deficient encephalopathy. Journal of neuropathology and experimental neurology, 1984, Volume: 43, Issue:3 Topics: Animals; Behavior, Animal; Brain; Brain Diseases; Disease Models, Animal; Energy Metabolism; Male; Microscopy, Electron; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency	1984
Effect of pyrithiamine treatment on potassium ion fluxes in rat cortical slices. Biochimica et biophysica acta, 1984, Jun-13, Volume: 773, Issue:1 Topics: Animals; Cerebral Cortex; Female; In Vitro Techniques; Kinetics; Oxygen Consumption; Phosphocreatine; Potassium; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Tetrodotoxin; Thiamine Deficiency; Veratridine	1984
Energy metabolism in the lateral vestibular nucleus in pyrithiamin-induced thiamin deficiency. Annals of the New York Academy of Sciences, 1982, Volume: 378 Topics: Adenosine Triphosphate; Animals; Diet; Energy Metabolism; Female; Glucose; Glycogen; Lactates; Lactic Acid; Mice; Phosphocreatine; Pyridinium Compounds; Pyrithiamine; Spinal Cord; Tectum Mesencephali; Thiamine Deficiency; Vestibular Nuclei; Vestibular Nucleus, Lateral	1982
Spontaneous open-field behavior in thiamin-deficient rats. The Journal of nutrition, 1982, Volume: 112, Issue:10 Topics: Animals; Behavior, Animal; Disease Models, Animal; Grooming; Male; Movement; Oxythiamine; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency	1982
Cholinergic therapy of abnormal open-field behavior in thiamin-deficient rats. The Journal of nutrition, 1982, Volume: 112, Issue:10 Topics: Animals; Behavior, Animal; Grooming; Male; Movement; Oxythiamine; Parasympatholytics; Parasympathomimetics; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency; Thiazoles	1982
Thiamine deficiency in the cat leads to severe learning deficits and to widespread neuroanatomical damage. Experimental brain research, 1982, Volume: 48, Issue:2 Topics: Animals; Brain; Cats; Discrimination Learning; Female; Male; Mental Recall; Motor Activity; Pyrithiamine; Seizures; Thiamine; Thiamine Deficiency	1982
Effect of a single, large dose injection of pyrithiamin on the thiamin deficiency of the mouse. Japanese journal of pharmacology, 1982, Volume: 32, Issue:5 Topics: Animals; Brain; Male; Mice; Microscopy, Electron; Pyridinium Compounds; Pyrithiamine; Thiamine Deficiency	1982
[An experimental study of pyrithiamine-induced encephalopathy in the rat. II. Light-and electron-microscopic observations on the early changes in the brain of the thiamine-deficient rat]. Rinsho shinkeigaku = Clinical neurology, 1982, Volume: 22, Issue:10 Topics: Acute Disease; Animals; Brain; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency	1982
The string test: an early behavioral change in thiamine deficiency. Pharmacology, biochemistry, and behavior, 1981, Volume: 14, Issue:2 Topics: Animals; Behavior, Animal; Male; Oxythiamine; Pyrithiamine; Rats; Thiamine Deficiency	1981
[Effect of pyrithiamine on rat sciatic nerve. (I) Morphological changes during the early stage of thiamine deficiency (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:7 Topics: Animals; Diet; Male; Pyridinium Compounds; Pyrithiamine; Rats; Sciatic Nerve; Thiamine; Thiamine Deficiency	1980
[Effect of pyrithiamine on rat sciatic nerve. (II) Morphological changes during the last stages of thiamine deficiency (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1980, Volume: 76, Issue:7 Topics: Animals; Diet; Male; Pyridinium Compounds; Pyrithiamine; Rats; Sciatic Nerve; Seizures; Thiamine Deficiency	1980
Impairment of behavior and acetylcholine metabolism in thiamine deficiency. The Journal of pharmacology and experimental therapeutics, 1981, Volume: 217, Issue:3 Topics: Acetylcholine; Animals; Male; Motor Skills; Parasympathetic Nervous System; Parasympatholytics; Parasympathomimetics; Physostigmine; Pyrithiamine; Rats; Thiamine Deficiency	1981
[Effect of oxythiamine and pyrithiamine on thiamine levels in the blood, liver and urine of rats (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1981, Volume: 78, Issue:6 Topics: Animals; Liver; Male; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency; Thiazoles	1981
Effects of thiamin deprivation and antagonism on voluntary ethanol intake in rats. The Journal of nutrition, 1980, Volume: 110, Issue:5 Topics: Acetaldehyde; Alcohol Drinking; Animals; Anorexia; Brain; Dopamine; Energy Intake; Male; Norepinephrine; Oxythiamine; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency	1980
Histamine-mediated neuronal death in a rat model of Wernicke's encephalopathy. Journal of neuroscience research, 1994, Aug-01, Volume: 38, Issue:5 Topics: Animals; Cell Death; Disease Models, Animal; Gliosis; Glutamic Acid; Glutamine; Hippocampus; Histamine; Histamine Release; Male; Methylhistidines; Microdialysis; Necrosis; Nerve Degeneration; Neuroglia; Pyrithiamine; Rats; Rats, Sprague-Dawley; Receptors, Glutamate; Receptors, N-Methyl-D-Aspartate; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy	1994
Thiamine deficiency in rats produces cognitive and memory deficits on spatial tasks that correlate with tissue loss in diencephalon, cortex and white matter. Behavioural brain research, 1995, Volume: 68, Issue:1 Topics: Animals; Avoidance Learning; Brain; Cerebral Cortex; Cognition Disorders; Diencephalon; Male; Maze Learning; Memory Disorders; Motor Activity; Pyrithiamine; Rats; Rats, Sprague-Dawley; Space Perception; Thiamine Deficiency	1995
Evidence for early blood-brain barrier breakdown in experimental thiamine deficiency in the mouse. Metabolic brain disease, 1995, Volume: 10, Issue:2 Topics: Animals; Behavior, Animal; Blood-Brain Barrier; Body Weight; Brain; Brain Chemistry; Histocytochemistry; Male; Mice; Mice, Inbred ICR; Oxythiamine; Pyrithiamine; Thiamine Deficiency	1995
Excitotoxic cytopathology, progression, and reversibility of thiamine deficiency-induced diencephalic lesions. Journal of neuropathology and experimental neurology, 1995, Volume: 54, Issue:2 Topics: Acute Disease; Analysis of Variance; Animals; Behavior, Animal; Diencephalon; Male; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine Deficiency; Wernicke Encephalopathy	1995
Extracellular glutamate is increased in thalamus during thiamine deficiency-induced lesions and is blocked by MK-801. Journal of neurochemistry, 1993, Volume: 61, Issue:6 Topics: Amino Acids; Animals; Dizocilpine Maleate; Extracellular Space; Hippocampus; Male; Microdialysis; Pyrithiamine; Rats; Rats, Sprague-Dawley; Reference Values; Seizures; Thalamus; Thiamine; Thiamine Deficiency; Time Factors	1993
A quantitative autoradiographic study of muscarinic cholinergic receptor subtypes in the brains of pyrithiamine-treated rats. Neurochemical research, 1995, Volume: 20, Issue:8 Topics: Animals; Antimetabolites; Autoradiography; Brain; Male; Pirenzepine; Pyrithiamine; Quinuclidinyl Benzilate; Radioligand Assay; Rats; Rats, Sprague-Dawley; Receptors, Muscarinic; Thiamine Deficiency	1995
Thiamine pyrophosphate-requiring enzymes are altered during pyrithiamine-induced thiamine deficiency in cultured human lymphoblasts. The Journal of nutrition, 1996, Volume: 126, Issue:7 Topics: Cell Culture Techniques; Cell Line; Humans; Ketoglutarate Dehydrogenase Complex; Leukocytes; Lymphocytes; Pyrithiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Transketolase	1996
Nitric oxide synthase activities are selectively decreased in vulnerable brain regions in thiamine deficiency. Neuroscience letters, 1996, Apr-12, Volume: 208, Issue:1 Topics: Animals; Antimetabolites; Brain; Diet; Male; Nitric Oxide Synthase; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine Deficiency	1996
Alterations in serotonin parameters in brain of thiamine-deficient rats are evident prior to the appearance of neurological symptoms. Journal of neurochemistry, 1996, Volume: 67, Issue:3 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amines; Animals; Autoradiography; Brain; Brain Chemistry; Chromatography, High Pressure Liquid; Feeding Behavior; Hydroxyindoleacetic Acid; Hypothermia; Ketanserin; Male; Monoamine Oxidase; Nervous System Diseases; Neurologic Examination; Pyrithiamine; Rats; Rats, Sprague-Dawley; Serotonin; Thiamine Deficiency; Tritium	1996
Brain pyruvate oxidation in experimental thiamin-deficiency encephalopathy. Clinica chimica acta; international journal of clinical chemistry, 1996, Nov-15, Volume: 255, Issue:1 Topics: Alcohol Amnestic Disorder; Animals; Brain; Brain Chemistry; Female; Hypothalamus; Ketoglutarate Dehydrogenase Complex; Lactic Acid; Mesencephalon; Mitochondria; Oxygen Consumption; Pyrithiamine; Pyruvate Dehydrogenase Complex; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Substrate Specificity; Thalamus; Thiamine Deficiency; Time Factors; Wernicke Encephalopathy	1996
Vesicular dysfunction during experimental thiamine deficiency is indicated by alterations in dopamine metabolism. European journal of pharmacology, 1996, Dec-19, Volume: 317, Issue:2-3 Topics: Adrenergic Uptake Inhibitors; Animals; Antimetabolites; Autoradiography; Brain Chemistry; Catecholamines; Dopamine; Ketanserin; Male; Norepinephrine; Pyrithiamine; Rats; Rats, Sprague-Dawley; Serotonin Antagonists; Synaptic Vesicles; Tetrabenazine; Thiamine Deficiency	1996
Metabolic and permeability changes caused by thiamine deficiency in immortalized rat brain microvessel endothelial cells. Brain research, 1997, May-09, Volume: 756, Issue:1-2 Topics: Actins; Animals; Antimetabolites; Blood Vessels; Capillary Permeability; Cell Line, Transformed; Cytoskeleton; Endothelium, Vascular; Glucose; Lactic Acid; Microcirculation; Oxidation-Reduction; Pyrithiamine; Rats; Tetrazolium Salts; Thiamine Deficiency; Thiazoles	1997
Increased cerebral free radical production during thiamine deficiency. Metabolic brain disease, 1997, Volume: 12, Issue:2 Topics: Animals; Antimetabolites; Brain Chemistry; Cerebral Cortex; Free Radicals; Glutathione; Histocytochemistry; Oxidative Stress; Pyrithiamine; Rats; Thalamus; Thiamine Deficiency	1997
Causality of parenchymal and vascular changes in rats with experimental thiamine deficiency encephalopathy. Pathology international, 1997, Volume: 47, Issue:11 Topics: Animals; Antimetabolites; Ataxia; Body Weight; Brain; Cerebral Hemorrhage; Glial Fibrillary Acidic Protein; Glycogen; Hypothermia; Immunohistochemistry; Inferior Colliculi; Male; Mammillary Bodies; Pyrithiamine; Rats; Rats, Sprague-Dawley; Seizures; Thalamus; Thiamine Deficiency; Vasodilation; Wernicke Encephalopathy	1997
Increased neuronal cell survival after L-deprenyl treatment in experimental thiamine deficiency. Journal of neuroscience research, 1998, Apr-15, Volume: 52, Issue:2 Topics: Animals; Behavior, Animal; Cell Count; Cell Survival; Disease Models, Animal; Drug Administration Schedule; Immunohistochemistry; Injections, Intraperitoneal; Male; Monoamine Oxidase Inhibitors; Neurons; Pyrithiamine; Rats; Rats, Sprague-Dawley; Selegiline; Thiamine Deficiency	1998
Changes in serotonergic neurons in the brain of pyrithiamine-induced acute thiamine-deficient mice. Acta neuropathologica, 1999, Volume: 98, Issue:6 Topics: Animals; Antimetabolites; Brain; Brain Chemistry; Male; Mice; Mice, Inbred ICR; Neurons; Pyrithiamine; Raphe Nuclei; Serotonin; Thiamine Deficiency	1999
Mechanisms of selective neuronal cell death due to thiamine deficiency. Annals of the New York Academy of Sciences, 1999, Volume: 893 Topics: Animals; Brain; Cell Death; Humans; Korsakoff Syndrome; Microglia; Neurons; Pyrithiamine; Rats; Receptors, N-Methyl-D-Aspartate; Thiamine Deficiency	1999
Thiamine deficiency results in metabolic acidosis and energy failure in cerebellar granule cells: an in vitro model for the study of cell death mechanisms in Wernicke's encephalopathy. Journal of neuroscience research, 2000, Oct-15, Volume: 62, Issue:2 Topics: Acidosis; Animals; Antimetabolites; Antioxidants; Cell Death; Cells, Cultured; Cerebellar Cortex; Energy Metabolism; Pyrithiamine; Rats; Rats, Sprague-Dawley; Thiamine Deficiency; Wernicke Encephalopathy	2000
Rats exposed to acute pyrithiamine-induced thiamine deficiency are more sensitive to the amnestic effects of scopolamine and MK-801: examination of working memory, response selection, and reinforcement contingencies. Behavioural brain research, 1999, Volume: 104, Issue:1-2 Topics: Acute Disease; Amnesia; Analysis of Variance; Animals; Behavior, Animal; Conditioning, Operant; Disease Models, Animal; Dizocilpine Maleate; Dose-Response Relationship, Drug; Drug Interactions; Korsakoff Syndrome; Male; Memory, Short-Term; Pyrithiamine; Rats; Rats, Sprague-Dawley; Reaction Time; Scopolamine; Thalamus; Thiamine Deficiency	1999
Aging potentiates the acute and chronic neurological symptoms of pyrithiamine-induced thiamine deficiency in the rodent. Behavioural brain research, 2001, Mar-15, Volume: 119, Issue:2 Topics: Age Factors; Animals; Brain; Korsakoff Syndrome; Male; Mental Recall; Pyrithiamine; Rats; Rats, Inbred F344; Thiamine Deficiency; Wernicke Encephalopathy	2001
Glucose induced IEG expression in the thiamin-deficient rat brain. Brain research, 2001, Feb-16, Volume: 892, Issue:1 Topics: Animals; Antimetabolites; Brain; Disease Models, Animal; Gene Expression Regulation; Genes, fos; Genes, Immediate-Early; Glucose; Humans; Organ Specificity; Pyrithiamine; Rats; Rats, Wistar; Thiamine Deficiency; Wernicke Encephalopathy	2001
Selective down-regulation of the astrocyte glutamate transporters GLT-1 and GLAST within the medial thalamus in experimental Wernicke's encephalopathy. Journal of neurochemistry, 2001, Volume: 78, Issue:3 Topics: Amino Acid Transport System X-AG; Animals; Antimetabolites; Astrocytes; ATP-Binding Cassette Transporters; Biological Transport; Carrier Proteins; Disease Models, Animal; Down-Regulation; Glutamic Acid; Humans; Immunoblotting; Immunohistochemistry; Intermediate Filament Proteins; Male; Parietal Lobe; Pyrithiamine; Rats; Rats, Sprague-Dawley; Statistics as Topic; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy	2001
Thiamine deficiency: selective impairment of the cerebellar serotonergic system. Neurology, 1978, Volume: 28, Issue:7 Topics: Animals; Cerebellum; Desipramine; Hypothalamus; In Vitro Techniques; Male; Neurotransmitter Agents; Phenyl Ethers; Propylamines; Pyrithiamine; Rats; Serotonin; Synaptic Transmission; Synaptosomes; Thiamine; Thiamine Deficiency	1978
The role of thiamine in nervous tissue. Neurochemical research, 1979, Volume: 4, Issue:2 Topics: Animals; Brain; Brain Diseases; Cattle; Coenzymes; Fishes; Ketoglutarate Dehydrogenase Complex; Nervous System Physiological Phenomena; Neural Conduction; Neurotransmitter Agents; Oxythiamine; Phosphorylation; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rabbits; Rats; Synaptic Transmission; Syndrome; Thiamin Pyrophosphokinase; Thiamine; Thiamine Deficiency; Thiamine Pyrophosphate; Transketolase	1979
Comparison of neurobehavioral effects induced by various experimental models of ataxia in the rat. Neurobehavioral toxicology, 1979, Volume: 1 Suppl 1 Topics: Acrylamide; Acrylamides; Animals; Ataxia; Male; Motor Skills; Nervous System; Pyridines; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency	1979
Measurement of ataxia and related neurological signs in the laboratory rat. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1979, Volume: 6, Issue:2 Topics: Acrylamides; Animals; Ataxia; Gait; Motor Activity; Neurologic Examination; Pyridines; Pyrithiamine; Rats; Reflex; Thiamine Deficiency	1979
Amino acid changes in thiamine-deficient encephalopathy: some implications for the pathogenesis of Friedreich's ataxia. The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 1979, Volume: 6, Issue:2 Topics: Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Friedreich Ataxia; gamma-Aminobutyric Acid; Glutamates; Glutamine; Glycine; Male; Pyrithiamine; Rats; Retina; Spinal Cord; Taurine; Thiamine Deficiency	1979
Effect of thiamine deficiency on brain serotonin turnover. Brain research, 1979, Dec-21, Volume: 179, Issue:1 Topics: Animals; Brain; Cerebellum; Cerebral Cortex; Corpus Striatum; Hippocampus; Hydroxyindoleacetic Acid; Hypothalamus; Male; Medulla Oblongata; Mesencephalon; Pyrithiamine; Rats; Serotonin; Thiamine Deficiency	1979
[Effects of oxythiamine and pyrithiamine on rat liver. --Biochemical and morphological changes in the thiamine deficient rat (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1979, Volume: 75, Issue:4 Topics: Animals; Body Weight; Diet; Lipid Metabolism; Liver; Male; Microscopy, Electron; Organ Size; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Thiazoles	1979
Effect of thiamine deficiency, pyrithiamine and oxythiamine on pyruvate metabolism in rat liver and brain in vivo. Journal of nutritional science and vitaminology, 1977, Volume: 23, Issue:5 Topics: Animals; Aspartic Acid; Body Weight; Brain; Decarboxylation; Glutamates; Liver; Male; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Pyruvates; Rats; Thiamine Deficiency; Thiazoles	1977
The effect of acute thiamine deficiency on brain tryptophan, serotonin and 5-hydroxyindoleacetic acid. Journal of neurochemistry, 1978, Volume: 31, Issue:4 Topics: Animals; Brain; Hydroxyindoleacetic Acid; Male; Pyrithiamine; Rats; Serotonin; Thiamine Deficiency; Tryptophan	1978
[Effect of oxythiamine and pyrithiamine on rat brain--morphological changes in the thiamine deficient rat brain (author's transl)]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1978, Volume: 74, Issue:8 Topics: Animals; Brain; Brain Chemistry; Male; Oxythiamine; Pyridinium Compounds; Pyrithiamine; Rats; Thiamine; Thiamine Deficiency; Thiazoles	1978
Biochemical changes in thiamine deficiencies. Journal of nutritional science and vitaminology, 1976, Volume: 22 SUPPL Topics: Aminobutyrates; Animals; Brain; Intestinal Mucosa; Intestine, Small; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Mitochondria, Liver; Myocardium; Organ Size; Oxythiamine; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Thiamine Deficiency; Transketolase	1976
MK-801 prevents brain lesions and delayed-nonmatching-to-sample deficits produced by pyrithiamine-induced encephalopathy in rats. Behavioral neuroscience, 1992, Volume: 106, Issue:4 Topics: Alcohol Amnestic Disorder; Animals; Appetitive Behavior; Brain Mapping; Discrimination Learning; Dizocilpine Maleate; Male; Mental Recall; Orientation; Pyrithiamine; Rats; Reaction Time; Receptors, N-Methyl-D-Aspartate; Retention, Psychology; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy	1992
Radio-frequency lesions of the thalamus produce delayed-nonmatching-to-sample impairments comparable to pyrithiamine-induced encephalopathy in rats. Behavioral neuroscience, 1992, Volume: 106, Issue:4 Topics: Alcohol Amnestic Disorder; Animals; Appetitive Behavior; Brain Mapping; Discrimination Learning; Male; Mammillary Bodies; Mental Recall; Orientation; Pyrithiamine; Rats; Retention, Psychology; Thalamus; Thiamine Deficiency; Wernicke Encephalopathy	1992
Pyrithiamine-induced thiamine deficiency results in decreased Ca(2+)-dependent release of glutamate from rat hippocampal slices. Metabolic brain disease, 1991, Volume: 6, Issue:3 Topics: Animals; Calcium; Glutamates; Glutamic Acid; Hippocampus; In Vitro Techniques; Ketoglutarate Dehydrogenase Complex; Male; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency	1991
Enzyme-cytochemical study of small ganglion cells in experimental thiamine deficiency: concerning the pain mechanism. Acta neuropathologica, 1991, Volume: 81, Issue:4 Topics: Animals; Ganglia, Spinal; Histocytochemistry; Male; Microscopy, Electron; Pain; Phosphoric Monoester Hydrolases; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency	1991
Analysis of aversively conditioned learning and memory in rats recovered from pyrithiamine-induced thiamine deficiency. Behavioral neuroscience, 1991, Volume: 105, Issue:3 Topics: Alcohol Amnestic Disorder; Analysis of Variance; Animals; Avoidance Learning; Discrimination Learning; Disease Models, Animal; Electroshock; Escape Reaction; Gliosis; Male; Mammillary Bodies; Memory; Models, Neurological; Pyrithiamine; Rats; Thalamus; Thiamine; Thiamine Deficiency; Visual Perception	1991
Impairment of olfactory, auditory, and spatial serial reversal learning in rats recovered from pyrithiamine-induced thiamine deficiency. Behavioral neuroscience, 1991, Volume: 105, Issue:3 Topics: Animals; Auditory Perception; Cues; Discrimination Learning; Male; Mammillary Bodies; Memory; Pyrithiamine; Rats; Reversal Learning; Serial Learning; Smell; Space Perception; Thalamus; Thiamine; Thiamine Deficiency	1991
Response latency and accuracy on a pretrained nonmatching-to-sample task in rats recovered from pyrithiamine-induced thiamine deficiency. Behavioral neuroscience, 1991, Volume: 105, Issue:3 Topics: Animals; Conditioning, Operant; Cues; Discrimination Learning; Male; Mammillary Bodies; Memory; Models, Neurological; Pyrithiamine; Rats; Reaction Time; Thalamus; Thiamine; Thiamine Deficiency	1991
Protective effects of the glutamate antagonist MK-801 on pyrithiamine-induced lesions and amino acid changes in rat brain. The Journal of neuroscience : the official journal of the Society for Neuroscience, 1990, Volume: 10, Issue:5 Topics: Amino Acids; Animals; Behavior, Animal; Brain; Dibenzocycloheptenes; Dizocilpine Maleate; Excitatory Amino Acid Antagonists; Glutamic Acid; Male; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency; Time Factors	1990
Changes in brain lipid composition in thiamine deficient rats. Japanese journal of pharmacology, 1990, Volume: 54, Issue:2 Topics: Animals; Brain Chemistry; Cerebrosides; Cholesterol; Injections, Intraperitoneal; Lipids; Oxythiamine; Phospholipids; Pyrithiamine; Rats; Rats, Inbred Strains; Sphingomyelins; Thiamine Deficiency; Triglycerides; Weight Gain	1990
Effect of pyrithiamine treatment and subsequent thiamine rehabilitation on regional cerebral amino acids and thiamine-dependent enzymes. Journal of neurochemistry, 1989, Volume: 52, Issue:4 Topics: Alanine; Amino Acids; Animals; Aspartic Acid; Brain; Brain Diseases; Glutamates; Glutamic Acid; Ketoglutarate Dehydrogenase Complex; Ketone Oxidoreductases; Male; Pyridinium Compounds; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency	1989
Effect of a deficiency of thiamine on brain pyruvate dehydrogenase: enzyme assay by three different methods. Journal of neurochemistry, 1988, Volume: 51, Issue:5 Topics: Animals; Brain; Carbon Dioxide; Coloring Agents; Enzyme Activation; Kinetics; Male; Mitochondria; NAD; Oxidation-Reduction; Pyrithiamine; Pyruvate Dehydrogenase Complex; Pyruvates; Pyruvic Acid; Rats; Rats, Inbred Strains; Tetrazolium Salts; Thiamine Deficiency; Thiamine Pyrophosphate	1988
Long-lasting changes in regional brain amino acids and monoamines in recovered pyrithiamine treated rats. Neurochemical research, 1988, Volume: 13, Issue:12 Topics: Amino Acids; Animals; Biogenic Monoamines; Brain Chemistry; Chromatography, High Pressure Liquid; Male; Pyridinium Compounds; Pyrithiamine; Rats; Thiamine Deficiency	1988
Metabolic studies of the edematous cerebral cortex of the pyrithiamine-treated thiamine-deficient rat. Brain research, 1988, Feb-16, Volume: 441, Issue:1-2 Topics: Amino Acids; Animals; Brain; Brain Edema; Cerebral Cortex; Glucose; Glycolysis; In Vitro Techniques; Male; Oxygen Consumption; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Reference Values; Thiamine Deficiency	1988
Activities of thiamine-dependent enzymes in two experimental models of thiamine deficiency encephalopathy: 3. Transketolase. Neurochemical research, 1987, Volume: 12, Issue:3 Topics: Animals; Brain; Brain Diseases; Male; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency; Transketolase	1987
Persistence of habituation deficits after neurological recovery from severe thiamine deprivation. Behavioural brain research, 1987, Volume: 26, Issue:1 Topics: Animals; Brain Diseases, Metabolic; Habituation, Psychophysiologic; Male; Pyrithiamine; Rats; Thiamine Deficiency	1987
Intrauterine growth retardation induced by thiamine deficiency and pyrithiamine during pregnancy in the rat. American journal of obstetrics and gynecology, 1985, Feb-15, Volume: 151, Issue:4 Topics: Animals; Body Weight; Brain; Female; Fetal Growth Retardation; Fetus; Liver; Organ Size; Placenta; Pregnancy; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine; Thiamine Deficiency	1985
Activities of thiamine-dependent enzymes in two experimental models of thiamine-deficiency encephalopathy: 1. The pyruvate dehydrogenase complex. Neurochemical research, 1985, Volume: 10, Issue:10 Topics: Animals; Brain Diseases, Metabolic; Brain Stem; Disease Models, Animal; Male; Pyrithiamine; Pyruvate Dehydrogenase Complex; Rats; Rats, Inbred Strains; Reflex; Thiamine; Thiamine Deficiency; Transketolase	1985
GABA-transaminase and glutamic acid decarboxylase changes in the brain of rats treated with pyrithiamine. Neurochemical research, 1985, Volume: 10, Issue:12 Topics: 4-Aminobutyrate Transaminase; Animals; Brain; Brain Chemistry; Choline O-Acetyltransferase; Glutamate Decarboxylase; Histocytochemistry; Male; Pyridinium Compounds; Pyrithiamine; Rats; Rats, Inbred Strains; Thiamine Deficiency	1985