pyrimidinones and Hemoperitoneum

pyrimidinones has been researched along with Hemoperitoneum* in 1 studies

Other Studies

1 other study(ies) available for pyrimidinones and Hemoperitoneum

ArticleYear
Hepatic hemorrhage as a consequence of rapid response to combined targeted therapy in metastatic melanoma.
    Journal of surgical oncology, 2015, Volume: 112, Issue:8

    A middle-aged female with metastatic melanoma was found to have hemoperitoneum after starting systemic therapy with the BRAF and MEK inhibitors dabrafenib and trametinib. Etiology proved to be bleeding from a known hepatic metastasis. The patient was managed conservatively and eventually resumed systemic therapy with ongoing response. This case serves to illustrate the possible deleterious effects of rapid tumor response after initiation of targeted systemic therapy in patients with metastatic melanoma.

    Topics: Antineoplastic Agents; Female; Hemoperitoneum; Humans; Imidazoles; Liver Neoplasms; Melanoma; Middle Aged; Oximes; Pyridones; Pyrimidinones; Skin Neoplasms

2015