Compounds > pyrimidine dimers
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pyrimidine dimers and Xeroderma Pigmentosum

pyrimidine dimers has been researched along with Xeroderma Pigmentosum in 152 studies

Research

Studies (152)

TimeframeStudies, this research(%)All Research%
pre-199048 (31.58)18.7374
1990's52 (34.21)18.2507
2000's36 (23.68)29.6817
2010's13 (8.55)24.3611
2020's3 (1.97)2.80

Authors

AuthorsStudies
Brazina, J; Burdova, K; Caldecott, KW; Fawcett, H; Gautam, A1
Alexandrov, LB; Castro, LP; Corradi, C; de Souza, TA; Garcia, CCM; Ienne, S; Menck, CFM; Moreno, NC; Munford, V; Ruiz, NQ1
Boeckmann, L; Emmert, S; Martens, MC1
Balbo Pogliano, C; Codilupi, T; Garajovà, Z; Naegeli, H; Rüthemann, P1
Masaki, T; Nakano, E; Nishigori, C; Ono, R; Takeuchi, S; Tsujimoto, M1
Beckwitt, EC; Bruchez, MP; David, SS; Fouquerel, E; Jang, S; Khuu, C; Kong, M; Kumar, N; Majumdar, C; Opresko, PL; Prasad, R; Rapić-Otrin, V; Van Houten, B; Watkins, SC; Wilson, SH1
Ghodke, H; Hsieh, CL; Rapić-Otrin, V; Van Houten, B; Wang, H; Watkins, SC; Woldemeskel, S1
D'Orazio, JA; Jarrett, SG1
Kang, TH; Park, JM1
Garcia, CCM; Menck, CFM; Moreno, NC; Schuch, AP; Schuch, NJ1
Geacintov, N; Gueranger, Q; Hendel, A; Livneh, Z; Ziv, O1
Hirano, M; Iwamoto, T; Kobayashi, N; Liu, YC; Mori, T; Nishiwaki, T; Okahashi, Y; Sarasin, A; Sugiura, S; Ueno, S; Yamamoto, A1
Chu, G; Yang, W1
Czyzewski, BK; Groisman, R; Iwai, S; Jeffrey, PD; Kawasaki, Y; Konícková, R; Nakatani, Y; Pavletich, NP; Scrima, A; Thomä, NH1
Geacintov, N; Livneh, Z; Nakajima, S; Yasui, A; Ziv, O1
Akagi, J; Hanaoka, F; Iwai, S; Nishi, R; Sugasawa, K1
Baker, CC; Boyle, J; Gozukara, E; Imoto, K; Khan, SG; Kraemer, KH; Metin, A; Oh, KS; Yamanegi, K; Zheng, ZM1
Cuadrado, N; Del Rio, M; García, E; García, M; Illera, N; Jorcano, JL; Larcher, F; Llames, S; Meana, A; Nagore, E; Puig, S; Recasens, M1
Broyde, S; Patel, DJ1
Biertümpfel, C; Gregory, M; Hanaoka, F; Kondo, Y; Lee, JY; Lehmann, AR; Masutani, C; Ramón-Maiques, S; Yang, W; Zhao, Y1
Aggarwal, AK; Jain, R; Johnson, RE; Prakash, L; Prakash, S; Silverstein, TD1
Giglia-Mari, G; Nonnekens, J; Theil, AF; Vermeulen, W; Wijgers, N1
Prakash, L; Prakash, S1
Cordeiro-Stone, M; Nikolaishvili-Feinberg, N1
Hanawalt, P; Itoh, T; Matsunaga, T; Nikaido, O; Spivak, G; Yamaizumi, M1
Chu, G; Tang, J1
Kannouche, P; Lehmann, AR; Sarasin, A; Stary, A1
Bates, SE; Bouziane, M; O'Connor, TR; Sarasin, A; Stary, A; Zhou, NY1
Imoto, K; Iwamoto, TA; Katsumi, S; Kobayashi, N; Miyagawa, S; Mori, T; Nakamura, Y; Nishiwaki, Y; Sarasin, A; Shirai, T; Sugiura, S; Yamamoto, A1
Lorenti-Garcia, C; Mosesso, P; Palitti, F; Penna, S; Pepe, G1
Horio, T; Itoh, T; Kunisada, T; Matsumura, Y; Miyauchi-Hashimoto, H; Okamoto, H; Tanaka, K; Yamazaki, F1
Choi, JH; Pfeifer, GP1
Alekseev, S; Kool, H; Moser, J; Mullenders, LH; van Zeeland, AA; Volker, M; Vrieling, H; Yasui, A1
Iwai, S; Takasawa, K; Vaisman, A; Woodgate, R1
El-Deiry, WS; Mori, T; Navaraj, A1
Boyle, J; Imoto, K; Khan, SG; Kraemer, KH; Oh, KS1
Adair, JE; Dement, GA; Maloney, SC; Reeves, R; Smerdon, MJ; Wertzler, KJ1
Becerril, C; Hamill, JD; McKay, BC; Smith, JM; Spronck, JC; Stubbert, LJ1
Cafardi, JA; Elmets, CA1
Ritter, MA; Williams, JR1
Takebe, H1
Charles, WC; Cleaver, JE; Kong, SH1
Fujiwara, Y; Kano, Y1
Cleaver, JE; Gruenert, DC1
Fornace, AJ; Seres, DS1
Cerutti, PA; Niggli, HJ1
Bender, MA1
Kantor, GJ; Setlow, RB1
Hanawalt, PC; Liu, SC; Parsons, CS1
Valerie, K1
Filon, AR; Klein, B; van der Eb, AJ; van Zeeland, AA1
Epe, B; Möller, K; Rünger, TM1
Bourre, F; Chevallier-Lagente, O; Eker, AP; Eveno, E; Hoeijmakers, JH; Kleijer, WJ; Nikaido, O; Quilliet, X; Roza, L; Stefanini, M1
Athwal, RS; Kaur, GP; Lloyd, RS; Mori, T; Nikaido, O; Rinaldy, A; Rinaldy, TL1
Inoue, H; Ishii, C; Takao, M; Yajima, H; Yasuhira, S; Yasui, A; Zhao, JH1
Admon, A; Chubatsu, LS; Fellous, R; Kim, J; Linn, S; Stahl, J1
Meschini, R; Mullenders, LH; van Hoffen, A; van Zeeland, AA; Venema, J1
Cordeiro-Stone, M; Farber, RA; Kaufmann, WK; King, SA; Wilson, SJ1
Ganesan, AK; Hanawalt, PC1
Cleaver, JE; Jones, C; Karentz, D; McDowell, M; Wood, R1
Prakash, L; Prakash, S; Sung, P; Watkins, JF1
Jones, CJ; Wood, RD1
Galloway, AM; Liuzzi, M; Paterson, MC1
Kraemer, KH; Parris, CN1
Hanawalt, PC; Lommel, L1
Hori, N; Ohtsuka, E; Tateishi, S; Yamaizumi, M1
Bohr, VA; Evans, MK; Ganges, MB; Nairn, RS; Robbins, JH; Tarone, RE1
Maher, VM; McCormick, JJ; McGregor, WG; Tung, BS; Wang, YC1
Afzal, V; Cleaver, JE; Feeney, L; Thomas, GH; Volpe, JP1
Friedberg, EC; Harada, Y; Itoh, T; Matsunaga, T; Nikaido, O; Shiomi, N; Shiomi, T; Wakasugi, M; Yamaizumi, M1
Ghosh, R; Mitchell, DL; Peng, CH1
Cleaver, JE5
Artuso, M; English, DR; Hall, J1
Cordeiro-Stone, M; Kaufmann, WK; Price, LK; Zaritskaya, LS1
Armier, J; Marionnet, C; Sarasin, A; Stary, A1
Bowman, KK; Hanawalt, PC; Smith, CA1
Kantor, GJ; Shanower, GA1
Hashimoto, MW; Ikenaga, M; Kobayashi, N; Mori, T; Muramatsu, T; Nakagawa, A; Shirai, T; Yamashina, Y1
Berg, RJ; de Gruijl, FR; Mullenders, LH; Ruven, HJ; Sands, AT1
Briley, LP; Svoboda, DL; Vos, JM1
Kobayashi, T; Morioka, H; Nakatsu, Y; Nikaido, O; Otsuka, E; Saijo, M; Takeuchi, S; Tanaka, K; Wakasugi, M1
Ganesan, AK; Hanawalt, PC; Hunt, J1
Chevallier-Lagente, O; Mezzina, M; Nikaido, O; Riou, L; Sarasin, A; Stary, A; Taïeb, A; Weeda, G; Zeng, L1
Araki, M; Hanaoka, F; Iwai, S; Kusumoto, R; Maekawa, T; Masutani, C; Nogimori, T; Yamada, A1
de Jong-Versteeg, A; Kalle, WH; Lehmann, AR; Mullenders, LH; van Hoffen, A; van Zeeland, AA1
Johnson, RE; Kondratick, CM; Prakash, L; Prakash, S1
Dammann, R; Pfeifer, GP1
Itoh, T; Mori, T; Ohkubo, H; Yamaizumi, M1
Emmert, S; Khan, SG; Kobayashi, N; Kraemer, KH1
Johnson, RE; Prakash, L; Prakash, S; Washington, MT1
Hitomi, K; Ikenaga, M; Kim, ST; Matsunaga, T; Mori, T; Nikaido, O; Otoshi, E; Todo, T; Yagi, T1
Wallin, H1
Lee, SH; Mahrenholz, A; Wang, M1
Hanaoka, F; Iwai, S; Masutani, C; Yamada, A1
Chu, G; Ford, JM; Hanawalt, PC; Hwang, BJ; Tang, JY1
Birch-Machin, MA; Nikaido, O; Ray, AJ; Rees, JL; Turner, R1
Johnson, RE; Prakash, L; Prakash, S; Yu, SL1
Horiki, S; Horio, T; Miyauchi-Hashimoto, H; Nikaido, O; Tanaka, K1
Tuteja, N; Tuteja, R1
Carty, MP; Dixon, K; Yao, J1
LeDoux, SP; Wilson, GL1
Lehmann, AR1
Friedberg, EC1
Bridges, BA; Lehmann, AR1
Lohman, PH; Zelle, B1
Zhestianikov, VD1
Carrier, WL; Lee, WH; Regan, JD; Smith, DP; Waters, R1
Painter, RB1
Kirk-Bell, S; Lehmann, AR1
Ahmed, FE; Setlow, RB1
Fujiwara, Y; Tatsumi, M1
Ikenaga, M; Ishizaki, K; Kato, M; Matsunaga, T; Nikaido, O1
Chen, Z; Essigmann, JM; Treiber, DK1
Feng, X; Lambert, MW; Parrish, DD1
Karcagi, V; Mullenders, LH; Natarajan, AT; van Hoffen, A; van Zeeland, AA; Venema, J1
Kibitel, JT; Yarosh, DB; Yee, V1
Barrett, SF; Kraemer, KH; Robbins, JH; Tarone, RE1
Charles, WC; Cleaver, JE; Jen, J; Mitchell, DL1
Coverley, D; Wood, RD1
Bergen Henegouwen, JB; Eker, AP; Hoeijmakers, JH; Jaspers, NG; Lohman, PH; Roza, L; Vermeulen, W1
Brash, DE; Mitchell, DL; Nairn, RS1
Barsalou, LS; Hanawalt, PC; Kantor, GJ1
Mayne, LV; Mullenders, LH; Natarajan, AT; van Hoffen, A; van Zeeland, AA; Venema, J1
Lam, LH; Reynolds, RJ2
Bayreuther, K; Francz, PI; Niggli, HJ; Rodemann, HP; Röthlisberger, R1
Bootsma, D; Bos, JL; Hoeijmakers, JH; Keijzer, W; Langeveld, JC; Mulder, MP; Smit, EM1
Chu, G; Patterson, M1
Applegate, LA; de Riel, JK; Henderson, EE; Ley, RD1
Kraemer, KH; Protić-Sabljić, M1
Cleaver, JE; Gruenert, DC; Killpack, S1
Auer, B; Burtscher, HJ; Hirsch-Kauffmann, M; Klocker, H; Schneider, R; Schweiger, M2
Cleaver, JE; Cortés, F; Lutze, LH; Mitchell, DL; Morgan, WF; Player, AN1
Cleaver, JE; Cortés, F; Karentz, D; Lutze, LH; Mitchell, DL; Morgan, WF; Player, AN; Vuksanovic, L1
Niggli, HJ; Röthlisberger, R1
Boyle, JM; Müller, H; Roth, M1
Eker, AP; Gentner, NE; MacFarlane, SJ; Middlestadt, MV; Paterson, MC; Weinfeld, M1
Cleaver, JE; Karentz, D; Mitchell, D1
Clarkson, JM; Haipek, CA; Mitchell, DL2
Gentner, NE; Johnson, LD; Paterson, MC; Weinfeld, M1
Francis, AA; Regan, JD1
Kantor, GJ; Player, AN1
Fujiwara, Y; Okui, T1
Jung, EG1
Hoeijmakers, JH; van Duin, M; Westerveld, A1
Lohman, PH; Roza, L; van der Schans, GP1

Reviews

17 review(s) available for pyrimidine dimers and Xeroderma Pigmentosum

ArticleYear
Xeroderma Pigmentosum: Gene Variants and Splice Variants.
    Genes, 2021, 07-29, Volume: 12, Issue:8

    Topics: DNA Damage; DNA Repair; Humans; Mutation; Pyrimidine Dimers; RNA Splicing; Xeroderma Pigmentosum

2021
Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis.
    Photochemistry and photobiology, 2017, Volume: 93, Issue:1

    Topics: Cyclic AMP; DNA Repair; Humans; Melanocortins; Melanocytes; Melanoma; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Signal Transduction; Ultraviolet Rays; United States; Xeroderma Pigmentosum

2017
Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation.
    International journal of molecular sciences, 2016, Nov-04, Volume: 17, Issue:11

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Repair; Guanine Nucleotide Exchange Factors; Humans; Protein Isoforms; Protein Processing, Post-Translational; Pyrimidine Dimers; Signal Transduction; Skin Neoplasms; Transcription, Genetic; Ubiquitin-Protein Ligases; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2016
Sunlight damage to cellular DNA: Focus on oxidatively generated lesions.
    Free radical biology & medicine, 2017, Volume: 107

    Topics: Antioxidants; Carcinogenesis; DNA; DNA Damage; DNA Repair; Humans; Oxidation-Reduction; Oxidative Stress; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Aging; Sunlight; Ultraviolet Rays; Xeroderma Pigmentosum

2017
Translesion DNA synthesis in eukaryotes: a one- or two-polymerase affair.
    Genes & development, 2002, Aug-01, Volume: 16, Issue:15

    Topics: Animals; Archaeal Proteins; Bacterial Proteins; Base Pair Mismatch; DNA; DNA Damage; DNA-Directed DNA Polymerase; Escherichia coli Proteins; Eukaryotic Cells; Humans; Mice; Models, Molecular; Neoplastic Syndromes, Hereditary; Nucleic Acid Conformation; Prokaryotic Cells; Protein Conformation; Proteins; Pyrimidine Dimers; Saccharomyces cerevisiae Proteins; Substrate Specificity; Xeroderma Pigmentosum

2002
Xeroderma pigmentosum complementation group E and UV-damaged DNA-binding protein.
    DNA repair, 2002, Aug-06, Volume: 1, Issue:8

    Topics: DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Humans; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

2002
T4 endonuclease V: review and application to dermatology.
    Expert opinion on biological therapy, 2008, Volume: 8, Issue:6

    Topics: Administration, Cutaneous; Adult; Animals; Bacteriophage T4; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; Drug Evaluation, Preclinical; Female; Genetic Predisposition to Disease; Humans; Liposomes; Male; Middle Aged; Neoplasms, Radiation-Induced; Photosensitivity Disorders; Pyrimidine Dimers; Rats; Skin Neoplasms; Sunburn; Viral Proteins; Xeroderma Pigmentosum

2008
[Defects in DNA repair and replication in neurocutaneous hereditary diseases].
    No to shinkei = Brain and nerve, 1984, Volume: 36, Issue:1

    Topics: Adolescent; Adult; Ataxia Telangiectasia; Cells, Cultured; Child; Child, Preschool; DNA Repair; DNA Replication; Electromyography; Humans; Infant; Infant, Newborn; Japan; Middle Aged; Neural Conduction; Neurologic Manifestations; Pyrimidine Dimers; Radiation Tolerance; Ultraviolet Rays; Xeroderma Pigmentosum

1984
Relationship of DNA lesions and their repair to chromosomal aberration production.
    Basic life sciences, 1980, Volume: 15

    Topics: Animals; Ataxia Telangiectasia; Cell Cycle; Chromatids; Chromosome Aberrations; Chromosomes; DNA; DNA Repair; Eukaryotic Cells; Fanconi Anemia; Humans; Lymphocytes; Models, Genetic; Mutagens; Pyrimidine Dimers; Recombination, Genetic; Xeroderma Pigmentosum

1980
Mutagenic lesions in photocarcinogenesis: the fate of pyrimidine photoproducts in repair-deficient disorders.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:4

    Topics: Animals; DNA Repair; Humans; Mutation; Photobiology; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1996
Molecular epidemiology of skin cancers: DNA repair and non-melanocytic skin cancer.
    Annali dell'Istituto superiore di sanita, 1996, Volume: 32, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cockayne Syndrome; DNA Damage; DNA Repair; Humans; Incidence; Mammals; Neoplasms, Radiation-Induced; Photosensitivity Disorders; Pyrimidine Dimers; Risk Factors; Skin Neoplasms; Sunlight; Ultraviolet Rays; Xeroderma Pigmentosum

1996
Unraveling DNA repair in human: molecular mechanisms and consequences of repair defect.
    Critical reviews in biochemistry and molecular biology, 2001, Volume: 36, Issue:3

    Topics: Alkylation; Animals; Ataxia Telangiectasia; Base Pair Mismatch; Carbon-Oxygen Lyases; Chromosome Breakage; Chromosome Fragility; Cockayne Syndrome; Cross-Linking Reagents; Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Adducts; DNA Damage; DNA Glycosylases; DNA Helicases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Activated Protein Kinase; DNA-Binding Proteins; Endonucleases; Forecasting; Genes, Recessive; Genetic Complementation Test; Genetic Predisposition to Disease; Hair Diseases; Humans; Intellectual Disability; Mammals; N-Glycosyl Hydrolases; Nail Diseases; Neoplasms; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Photochemistry; Photosensitivity Disorders; Protein Serine-Threonine Kinases; Proteins; Pyrimidine Dimers; Transcription Factor TFIIH; Transcription Factors; Transcription Factors, TFII; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group D Protein

2001
Base excision repair of mitochondrial DNA damage in mammalian cells.
    Progress in nucleic acid research and molecular biology, 2001, Volume: 68

    Topics: Alkylation; Animals; Bleomycin; Caspases; Cerebellar Cortex; CHO Cells; Cricetinae; Cricetulus; DNA Damage; DNA Ligases; DNA Repair; DNA, Mitochondrial; DNA, Neoplasm; Humans; Insulinoma; Mammals; Mitochondria; Mutagens; Neurons; Nitric Oxide; Oxidants; Oxidation-Reduction; Oxidative Stress; Pancreatic Neoplasms; Polymerase Chain Reaction; Pyrimidine Dimers; Reactive Oxygen Species; Ultraviolet Rays; Vitamin K 3; Xeroderma Pigmentosum

2001
Xeroderma pigmentosum: recent studies on the DNA repair defects.
    Archives of pathology & laboratory medicine, 1978, Volume: 102, Issue:1

    Topics: Cell Fusion; DNA; DNA Repair; DNA Replication; Genetic Complementation Test; Humans; Pyrimidine Dimers; Thymine Nucleotides; Ultraviolet Rays; Xeroderma Pigmentosum

1978
DNA repair.
    Essays in biochemistry, 1977, Volume: 13

    Topics: Aging; Alkylating Agents; Animals; Caffeine; Carcinogens; Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Ligases; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; DNA, Bacterial; DNA, Single-Stranded; Endonucleases; Escherichia coli; Exonucleases; Genes; Genetic Diseases, Inborn; Glycoside Hydrolases; Humans; Models, Biological; Mutation; Pyrimidine Dimers; Telangiectasia, Hereditary Hemorrhagic; Ultraviolet Rays; Xeroderma Pigmentosum

1977
DNA repair and its coupling to DNA replication in eukaryotic cells.
    Biochimica et biophysica acta, 1978, Dec-11, Volume: 516, Issue:4

    Topics: Caffeine; Cells; Cells, Cultured; Deoxyribodipyrimidine Photo-Lyase; Deoxyribonucleotides; DNA Repair; DNA Replication; Eukaryotic Cells; Fibroblasts; HeLa Cells; Pyrimidine Dimers; Xeroderma Pigmentosum

1978
DNA excision repair in mammalian cell extracts.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 1991, Volume: 13, Issue:9

    Topics: Animals; Cell Line; Cell-Free System; DNA; DNA Damage; DNA Ligases; DNA Repair; DNA-Binding Proteins; DNA-Directed RNA Polymerases; DNA, Circular; Genetic Complementation Test; Humans; Mammals; Models, Genetic; Models, Molecular; Plasmids; Pyrimidine Dimers; Pyrimidines; Replication Protein A; Ultraviolet Rays; Xeroderma Pigmentosum

1991

Other Studies

135 other study(ies) available for pyrimidine dimers and Xeroderma Pigmentosum

ArticleYear
APE1-dependent base excision repair of DNA photodimers in human cells.
    Molecular cell, 2023, 10-19, Volume: 83, Issue:20

    Topics: DNA; DNA Damage; DNA Repair; Humans; Pyrimidine Dimers; Ultraviolet Rays; X-ray Repair Cross Complementing Protein 1; Xeroderma Pigmentosum

2023
Whole-exome sequencing reveals the impact of UVA light mutagenesis in xeroderma pigmentosum variant human cells.
    Nucleic acids research, 2020, 02-28, Volume: 48, Issue:4

    Topics: Cell Line; DNA Damage; DNA Repair; DNA Replication; Exome Sequencing; Humans; Mutagenesis; Mutation; Oxidative Stress; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

2020
Chromatin remodeler CHD1 promotes XPC-to-TFIIH handover of nucleosomal UV lesions in nucleotide excision repair.
    The EMBO journal, 2017, 11-15, Volume: 36, Issue:22

    Topics: Cell Death; Chromatin; Chromatin Assembly and Disassembly; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Genome, Human; HEK293 Cells; HeLa Cells; Humans; Nucleosomes; Pyrimidine Dimers; RNA, Small Interfering; Transcription Factor TFIIH; Ultraviolet Rays; Xeroderma Pigmentosum

2017
Xeroderma Pigmentosum Diagnosis Using a Flow Cytometry-Based Nucleotide Excision Repair Assay.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:2

    Topics: Adult; Aged; Antibodies, Monoclonal; Cell Cycle; DNA Repair; Female; Fibroblasts; Flow Cytometry; Healthy Volunteers; Humans; Male; Middle Aged; Pyrimidine Dimers; Skin; Ultraviolet Rays; Xeroderma Pigmentosum

2018
Damage sensor role of UV-DDB during base excision repair.
    Nature structural & molecular biology, 2019, Volume: 26, Issue:8

    Topics: Cell Line; DNA Damage; DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Binding Proteins; Guanine; Humans; Kinetics; Models, Molecular; Protein Binding; Protein Conformation; Protein Interaction Mapping; Pyrimidine Dimers; Recombinant Proteins; Single Molecule Imaging; Substrate Specificity; Xeroderma Pigmentosum

2019
Single-molecule analysis reveals human UV-damaged DNA-binding protein (UV-DDB) dimerizes on DNA via multiple kinetic intermediates.
    Proceedings of the National Academy of Sciences of the United States of America, 2014, May-06, Volume: 111, Issue:18

    Topics: Amino Acid Substitution; DNA; DNA Damage; DNA-Binding Proteins; Humans; Kinetics; Microscopy, Fluorescence; Models, Molecular; Mutagenesis, Site-Directed; Nucleic Acid Conformation; Osmolar Concentration; Protein Conformation; Protein Multimerization; Pyrimidine Dimers; Quantum Dots; Ultraviolet Rays; Xeroderma Pigmentosum

2014
Reduced efficiency and increased mutagenicity of translesion DNA synthesis across a TT cyclobutane pyrimidine dimer, but not a TT 6-4 photoproduct, in human cells lacking DNA polymerase eta.
    DNA repair, 2008, Oct-01, Volume: 7, Issue:10

    Topics: Cells, Cultured; DNA; DNA-Directed DNA Polymerase; Fibroblasts; Humans; Mutagenesis; Plasmids; Pyrimidine Dimers; Sequence Analysis, DNA; Xeroderma Pigmentosum

2008
Comparative study of nucleotide excision repair defects between XPD-mutated fibroblasts derived from trichothiodystrophy and xeroderma pigmentosum patients.
    DNA repair, 2008, Dec-01, Volume: 7, Issue:12

    Topics: Cells, Cultured; DNA Damage; DNA Repair; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Genome, Human; Humans; Pyrimidine Dimers; Radiation Tolerance; Replication Protein A; Transcription Factor TFIIH; Trichothiodystrophy Syndromes; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group D Protein

2008
Here comes the sun: recognition of UV-damaged DNA.
    Cell, 2008, Dec-26, Volume: 135, Issue:7

    Topics: DNA Repair; Humans; Pyrimidine Dimers; Sunlight; Ultraviolet Rays; Xeroderma Pigmentosum

2008
Structural basis of UV DNA-damage recognition by the DDB1-DDB2 complex.
    Cell, 2008, Dec-26, Volume: 135, Issue:7

    Topics: Animals; DNA Damage; DNA Repair; DNA-Binding Proteins; Humans; Models, Molecular; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum; Zebrafish; Zebrafish Proteins

2008
DNA polymerase zeta cooperates with polymerases kappa and iota in translesion DNA synthesis across pyrimidine photodimers in cells from XPV patients.
    Proceedings of the National Academy of Sciences of the United States of America, 2009, Jul-14, Volume: 106, Issue:28

    Topics: Cells, Cultured; DNA; DNA Repair; DNA-Directed DNA Polymerase; Humans; Models, Genetic; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

2009
Two-step recognition of DNA damage for mammalian nucleotide excision repair: Directional binding of the XPC complex and DNA strand scanning.
    Molecular cell, 2009, Nov-25, Volume: 36, Issue:4

    Topics: Adenosine Triphosphatases; Cell Line; Cell-Free System; DNA; DNA Damage; DNA Repair; Humans; Models, Genetic; Nucleic Acid Conformation; Protein Binding; Pyrimidine Dimers; Transcription Factor TFIIH; Xeroderma Pigmentosum

2009
XPC branch-point sequence mutations disrupt U2 snRNP binding, resulting in abnormal pre-mRNA splicing in xeroderma pigmentosum patients.
    Human mutation, 2010, Volume: 31, Issue:2

    Topics: Base Sequence; Cell Line; Cell Survival; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Exons; Genome, Human; Humans; Molecular Sequence Data; Mutation; Phenotype; Protein Binding; Pyrimidine Dimers; Ribonuclease H; Ribonucleoprotein, U2 Small Nuclear; RNA Precursors; RNA Splicing; RNA, Messenger; Ultraviolet Rays; Xeroderma Pigmentosum

2010
In vivo assessment of acute UVB responses in normal and Xeroderma Pigmentosum (XP-C) skin-humanized mouse models.
    The American journal of pathology, 2010, Volume: 177, Issue:2

    Topics: Animals; Cells, Cultured; Disease Models, Animal; DNA Damage; DNA Repair; Humans; Keratinocytes; Mice; Pyrimidine Dimers; Skin; Skin Pigmentation; Ultraviolet Rays; Xeroderma Pigmentosum

2010
DNA repair: How to accurately bypass damage.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Biocatalysis; Crystallography, X-Ray; DNA; DNA Damage; DNA Repair; DNA-Directed DNA Polymerase; Humans; Models, Molecular; Mutation, Missense; Pyrimidine Dimers; Saccharomyces cerevisiae; Skin Neoplasms; Structure-Activity Relationship; Xeroderma Pigmentosum

2010
Structure and mechanism of human DNA polymerase eta.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Adenosine Triphosphate; Base Sequence; Biocatalysis; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Damage; DNA-Directed DNA Polymerase; Humans; Kinetics; Models, Molecular; Mutation, Missense; Pyrimidine Dimers; Structure-Activity Relationship; Xeroderma Pigmentosum

2010
Structural basis for the suppression of skin cancers by DNA polymerase eta.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Biocatalysis; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Damage; DNA-Directed DNA Polymerase; Humans; Kinetics; Models, Molecular; Mutation, Missense; Nucleic Acid Conformation; Protein Structure, Tertiary; Pyrimidine Dimers; Saccharomyces cerevisiae; Skin Neoplasms; Structure-Activity Relationship; Xeroderma Pigmentosum

2010
Slowly progressing nucleotide excision repair in trichothiodystrophy group A patient fibroblasts.
    Molecular and cellular biology, 2011, Volume: 31, Issue:17

    Topics: Blotting, Western; Cell Line; Cell Survival; Cells, Cultured; Chromatin Immunoprecipitation; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Endonucleases; Fibroblasts; Humans; Pyrimidine Dimers; Time Factors; Transcription Factor TFIIH; Transcription Factors; Trichothiodystrophy Syndromes; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2011
Asymmetry of DNA replication and translesion synthesis of UV-induced thymine dimers.
    Mutation research, 2002, Dec-29, Volume: 510, Issue:1-2

    Topics: Cell Line; DNA Damage; DNA Repair; DNA Replication; HeLa Cells; Humans; Models, Biological; Mutagenesis; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

2002
Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers.
    DNA repair, 2002, Aug-06, Volume: 1, Issue:8

    Topics: alpha-Fetoproteins; Cells, Cultured; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; Fibroblasts; Genes, p53; Humans; Neurofilament Proteins; Pyrimidine Dimers; Radiation Tolerance; RNA; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

2002
Role of DNA polymerase eta in the UV mutation spectrum in human cells.
    The Journal of biological chemistry, 2003, May-23, Volume: 278, Issue:21

    Topics: Base Sequence; beta-Galactosidase; Caffeine; Cell Cycle; Cell Line; Cell Line, Transformed; Cell Survival; DNA Damage; DNA-Directed DNA Polymerase; Gene Deletion; Genetic Vectors; Humans; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Pyrimidine Dimers; Sequence Analysis, DNA; Simian virus 40; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

2003
Efficient repair of cyclobutane pyrimidine dimers at mutational hot spots is restored in complemented Xeroderma pigmentosum group C and trichothiodystrophy/xeroderma pigmentosum group D cells.
    Journal of molecular biology, 2003, Sep-12, Volume: 332, Issue:2

    Topics: Cell Line; Databases, Nucleic Acid; DNA Damage; DNA Repair; DNA, Complementary; Exons; Fibroblasts; Genes, p53; Genetic Therapy; Hair Diseases; Humans; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

2003
Trichothiodystrophy fibroblasts are deficient in the repair of ultraviolet-induced cyclobutane pyrimidine dimers and (6-4)photoproducts.
    The Journal of investigative dermatology, 2004, Volume: 122, Issue:2

    Topics: DNA Helicases; DNA Repair; DNA-Binding Proteins; Fibroblasts; Hair Diseases; Humans; In Vitro Techniques; Microscopy, Fluorescence; Photochemistry; Pyrimidine Dimers; Severity of Illness Index; Skin; Xeroderma Pigmentosum

2004
Potassium bromate but not X-rays cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblasts.
    Cytogenetic and genome research, 2004, Volume: 104, Issue:1-4

    Topics: Bromates; Chromosomal Instability; Cockayne Syndrome; Comet Assay; DNA; DNA Damage; DNA Repair; Fibroblasts; Guanine; Humans; Oxidation-Reduction; Photochemistry; Pyrimidine Dimers; Radiation Tolerance; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

2004
XPA gene-deficient, SCF-transgenic mice with epidermal melanin are resistant to UV-induced carcinogenesis.
    The Journal of investigative dermatology, 2004, Volume: 123, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dermatitis; DNA Damage; DNA-Binding Proteins; Epidermis; Immunity, Innate; In Situ Nick-End Labeling; Langerhans Cells; Melanins; Melanocytes; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Pyrimidine Dimers; Skin Neoplasms; Stem Cell Factor; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2004
The role of DNA polymerase eta in UV mutational spectra.
    DNA repair, 2005, Feb-03, Volume: 4, Issue:2

    Topics: Base Pairing; Base Sequence; Cells, Cultured; Cytosine; Deamination; DNA Damage; DNA Replication; DNA-Directed DNA Polymerase; Humans; Kidney; Molecular Sequence Data; Mutagenesis; Mutation; Nucleic Acid Synthesis Inhibitors; Pyrimidine Dimers; RNA, Small Interfering; Ultraviolet Rays; Xeroderma Pigmentosum

2005
The UV-damaged DNA binding protein mediates efficient targeting of the nucleotide excision repair complex to UV-induced photo lesions.
    DNA repair, 2005, May-02, Volume: 4, Issue:5

    Topics: Cell Nucleus; Dimerization; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Fibroblasts; Humans; Photochemistry; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2005
DNA polymerase iota-dependent translesion replication of uracil containing cyclobutane pyrimidine dimers.
    DNA repair, 2006, Feb-03, Volume: 5, Issue:2

    Topics: Carcinogens; Catalysis; DNA Damage; DNA Polymerase iota; DNA Primers; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Dose-Response Relationship, Drug; Glutathione Transferase; Humans; Hypoxanthine Phosphoribosyltransferase; Kinetics; Mutagens; Mutation; Pyrimidine Dimers; Time Factors; Ultraviolet Rays; Uracil; Xeroderma Pigmentosum

2006
Cooperation between BRCA1 and p53 in repair of cyclobutane pyrimidine dimers.
    Cancer biology & therapy, 2005, Volume: 4, Issue:12

    Topics: BRCA1 Protein; Breast Neoplasms; Cell Line, Tumor; Cell Survival; DNA Damage; DNA Repair; DNA-Binding Proteins; Dose-Response Relationship, Radiation; Gene Expression Regulation, Neoplastic; Humans; Osteosarcoma; Pyrimidine Dimers; Time Factors; Tumor Suppressor Protein p53; Ultraviolet Rays; Xeroderma Pigmentosum

2005
Influence of XPB helicase on recruitment and redistribution of nucleotide excision repair proteins at sites of UV-induced DNA damage.
    DNA repair, 2007, Sep-01, Volume: 6, Issue:9

    Topics: Cells, Cultured; DNA Damage; DNA Helicases; DNA Repair; DNA Replication; DNA-Binding Proteins; Endonucleases; Fibroblasts; Fluorescent Antibody Technique; Humans; Mutation; Nuclear Proteins; Pyrimidine Dimers; Transcription Factors; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein; Xeroderma Pigmentosum Group D Protein

2007
High-mobility group A1 proteins inhibit expression of nucleotide excision repair factor xeroderma pigmentosum group A.
    Cancer research, 2007, Jul-01, Volume: 67, Issue:13

    Topics: Base Sequence; Cell Line, Tumor; Cyclobutanes; Disease Progression; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; HMGA1a Protein; Humans; Molecular Sequence Data; Mutagenesis; Neoplasms; Promoter Regions, Genetic; Pyrimidine Dimers; Xeroderma Pigmentosum

2007
DDB2-independent role for p53 in the recovery from ultraviolet light-induced replication arrest.
    Cell cycle (Georgetown, Tex.), 2007, Jul-15, Volume: 6, Issue:14

    Topics: Animals; Cell Cycle; Cells, Cultured; DNA; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; Fibroblasts; Humans; Pyrimidine Dimers; RNA Interference; Tumor Suppressor Protein p53; Ultraviolet Rays; Xeroderma Pigmentosum

2007
Fluorescent-light-induced lethality and DNA repair in normal and xeroderma pigmentosum fibroblasts.
    Biochimica et biophysica acta, 1981, Aug-27, Volume: 655, Issue:1

    Topics: Cell Survival; Cells, Cultured; DNA Repair; Endonucleases; Fibroblasts; Fluorescence; Humans; Male; Middle Aged; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1981
Efficiency of repair of pyrimidine dimers and psoralen monoadducts in normal and xeroderma pigmentosum human cells.
    Photochemistry and photobiology, 1984, Volume: 40, Issue:5

    Topics: Cell Line; Cells, Cultured; DNA Repair; Fibroblasts; Furocoumarins; Humans; Pyrimidine Dimers; Skin; Xeroderma Pigmentosum

1984
Defective thymine dimer excision from xeroderma pigmentosum chromatin and its characteristic catalysis by cell-free extracts.
    Carcinogenesis, 1983, Volume: 4, Issue:11

    Topics: Cell Line; Chromatin; Female; Fetus; Humans; Lung; Pregnancy; Pyrimidine Dimers; Skin; Ultraviolet Rays; Xeroderma Pigmentosum

1983
Repair of psoralen adducts in human DNA: differences among xeroderma pigmentosum complementation groups.
    The Journal of investigative dermatology, 1984, Volume: 82, Issue:4

    Topics: DNA; DNA Repair; Furocoumarins; Humans; PUVA Therapy; Pyrimidine Dimers; Xeroderma Pigmentosum

1984
Detection of DNA single-strand breaks during the repair of UV damage in xeroderma pigmentosum cells.
    Radiation research, 1983, Volume: 93, Issue:1

    Topics: Cells, Cultured; Cytarabine; DNA; DNA Repair; DNA-Directed DNA Polymerase; Humans; Hydroxyurea; Nucleic Acid Synthesis Inhibitors; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1983
Temperature dependence of induction of cyclobutane-type pyrimidine photodimers in human fibroblasts by 313 nm light.
    Photochemistry and photobiology, 1983, Volume: 37, Issue:4

    Topics: Cell Line; Cyclobutanes; Fibroblasts; Humans; Pyrimidine Dimers; Skin; Ultraviolet Rays; Xeroderma Pigmentosum

1983
Correlation between inactivation of human cells and numbers of pyrimidine dimers induced by sun lamp and 254 nm radiation.
    Photochemistry and photobiology, 1982, Volume: 35, Issue:2

    Topics: Cell Line; Cell Survival; Fibroblasts; Humans; Lighting; Pyrimidine Dimers; Skin; Sunlight; Ultraviolet Rays; Xeroderma Pigmentosum

1982
DNA repair responses in human skin cells.
    The Journal of investigative dermatology, 1981, Volume: 77, Issue:1

    Topics: Bacteria; DNA Repair; Epidermal Cells; Furocoumarins; Humans; Photochemotherapy; Psoriasis; PUVA Therapy; Pyrimidine Dimers; Skin; Xeroderma Pigmentosum

1981
Replacing tryptophan-128 of T4 endonuclease V with a serine residue results in decreased enzymatic activity in vitro and in vivo.
    Nucleic acids research, 1995, Sep-25, Volume: 23, Issue:18

    Topics: Base Sequence; Cells, Cultured; Deoxyribonuclease (Pyrimidine Dimer); Deoxyribonuclease IV (Phage T4-Induced); DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Escherichia coli; Escherichia coli Proteins; Humans; Lyases; Molecular Sequence Data; Mutagenesis, Site-Directed; N-Glycosyl Hydrolases; Poly dA-dT; Pyrimidine Dimers; Recombinant Fusion Proteins; Serine; Tryptophan; Ultraviolet Rays; Viral Proteins; Xeroderma Pigmentosum

1995
Survival of UV-irradiated vaccinia virus in normal and xeroderma pigmentosum fibroblasts; evidence for repair of UV-damaged viral DNA.
    Mutation research, 1994, May-01, Volume: 307, Issue:1

    Topics: Animals; Cell Line; Diploidy; DNA Damage; DNA Repair; DNA, Viral; Fibroblasts; Genetic Complementation Test; Humans; Pyrimidine Dimers; Tumor Cells, Cultured; Ultraviolet Rays; Vaccinia virus; Vero Cells; Xeroderma Pigmentosum

1994
Processing of directly and indirectly ultraviolet-induced DNA damage in human cells.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1995, Volume: 139

    Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA; DNA Damage; DNA Repair; DNA, Bacterial; DNA, Recombinant; Genetic Vectors; Herpesvirus 4, Human; Humans; Lymphocytes; Methylene Blue; Neoplasms, Radiation-Induced; Oxidative Stress; Oxygen; Plasmids; Pyrimidine Dimers; Radiation-Sensitizing Agents; Recombinant Fusion Proteins; Singlet Oxygen; Skin Neoplasms; Tissue Extracts; Ultraviolet Rays; Xeroderma Pigmentosum

1995
Different removal of ultraviolet photoproducts in genetically related xeroderma pigmentosum and trichothiodystrophy diseases.
    Cancer research, 1995, Oct-01, Volume: 55, Issue:19

    Topics: Cell Line; Chloramphenicol O-Acetyltransferase; DNA Repair; Genes, Reporter; Hair; Humans; Luciferases; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1995
A xeroderma pigmentosum complementation group A related gene: confirmation using monoclonal antibodies against the cyclobutane dimer and (6-4) photoproduct.
    Mutation research, 1993, Volume: 293, Issue:2

    Topics: Antibodies, Monoclonal; Cell Line; Chromosomes, Human, Pair 8; Cloning, Molecular; Cosmids; DNA; DNA Repair; Genes; Genetic Complementation Test; Humans; Polymerase Chain Reaction; Pyrimidine Dimers; Xeroderma Pigmentosum

1993
A eukaryotic gene encoding an endonuclease that specifically repairs DNA damaged by ultraviolet light.
    The EMBO journal, 1995, May-15, Volume: 14, Issue:10

    Topics: Amino Acid Sequence; Base Sequence; Cloning, Molecular; DNA Damage; DNA Repair; Endonucleases; Escherichia coli; Eukaryotic Cells; Fungal Proteins; Genes, Fungal; Genetic Complementation Test; Humans; Molecular Sequence Data; Mutation; Neurospora crassa; Pyrimidine Dimers; Radiation Tolerance; Saccharomyces cerevisiae; Substrate Specificity; Ultraviolet Rays; Xeroderma Pigmentosum

1995
Implication of mammalian ribosomal protein S3 in the processing of DNA damage.
    The Journal of biological chemistry, 1995, Jun-09, Volume: 270, Issue:23

    Topics: Amino Acid Sequence; Cells, Cultured; Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Damage; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Endodeoxyribonucleases; Escherichia coli Proteins; Humans; Lyases; Molecular Sequence Data; Multienzyme Complexes; N-Glycosyl Hydrolases; Pyrimidine Dimers; Ribosomal Proteins; Substrate Specificity; Xeroderma Pigmentosum

1995
Transcription-coupled repair removes both cyclobutane pyrimidine dimers and 6-4 photoproducts with equal efficiency and in a sequential way from transcribed DNA in xeroderma pigmentosum group C fibroblasts.
    The EMBO journal, 1995, Jan-16, Volume: 14, Issue:2

    Topics: Cells, Cultured; DNA; DNA Repair; Endodeoxyribonucleases; Escherichia coli Proteins; Fibroblasts; Humans; Photochemistry; Pyrimidine Dimers; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1995
Xeroderma pigmentosum variant: generation and characterization of fibroblastic cell lines transformed with SV40 large T antigen.
    Experimental cell research, 1995, Volume: 217, Issue:1

    Topics: Antigens, Polyomavirus Transforming; Benzopyrenes; Cell Line, Transformed; Cell Separation; Clone Cells; DNA Repair; DNA Replication; Fibroblasts; Humans; Infant, Newborn; Male; Plasmids; Pyrimidine Dimers; Simian virus 40; Ultraviolet Rays; Xeroderma Pigmentosum

1995
Removal of cyclobutane pyrimidine dimers from a UV-irradiated shuttle vector introduced into human cells.
    Somatic cell and molecular genetics, 1994, Volume: 20, Issue:3

    Topics: beta-Galactosidase; Cell Line; DNA; DNA Repair; Genetic Vectors; Humans; Lac Operon; Plasmids; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1994
Mutation and expression of the XPA gene in revertants and hybrids of a xeroderma pigmentosum cell line.
    Somatic cell and molecular genetics, 1994, Volume: 20, Issue:4

    Topics: Amino Acid Sequence; Animals; Base Sequence; Cell Line, Transformed; CHO Cells; Cricetinae; Cricetulus; DNA Repair; DNA-Binding Proteins; Humans; Hybrid Cells; Molecular Sequence Data; Mutation; Polymerase Chain Reaction; Pyrimidine Dimers; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

1994
Negative superhelicity promotes ATP-dependent binding of yeast RAD3 protein to ultraviolet-damaged DNA.
    The Journal of biological chemistry, 1994, Mar-18, Volume: 269, Issue:11

    Topics: Adenosine Triphosphatases; Adenosine Triphosphate; Animals; Cattle; DNA; DNA Damage; DNA Helicases; DNA Repair; DNA Topoisomerases, Type I; DNA, Circular; DNA, Superhelical; DNA, Viral; Genes, Fungal; Humans; Kinetics; Pyrimidine Dimers; Saccharomyces cerevisiae; Saccharomyces cerevisiae Proteins; Thymus Gland; Ultraviolet Rays; Xeroderma Pigmentosum

1994
Preferential binding of the xeroderma pigmentosum group A complementing protein to damaged DNA.
    Biochemistry, 1993, Nov-16, Volume: 32, Issue:45

    Topics: Base Sequence; Binding Sites; Cloning, Molecular; DNA; DNA Damage; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; Humans; Molecular Sequence Data; Pyrimidine Dimers; Recombinant Proteins; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

1993
Metabolic processing of cyclobutyl pyrimidine dimers and (6-4) photoproducts in UV-treated human cells. Evidence for distinct excision-repair pathways.
    The Journal of biological chemistry, 1994, Jan-14, Volume: 269, Issue:2

    Topics: DNA; DNA Damage; DNA Repair; Humans; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1994
Ultraviolet-induced mutations in Cockayne syndrome cells are primarily caused by cyclobutane dimer photoproducts while repair of other photoproducts is normal.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Aug-01, Volume: 90, Issue:15

    Topics: Base Sequence; Cells, Cultured; Cockayne Syndrome; DNA Repair; Genes, Bacterial; Humans; In Vitro Techniques; Molecular Sequence Data; Mutagenesis; Plasmids; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1993
Increased UV resistance of a xeroderma pigmentosum revertant cell line is correlated with selective repair of the transcribed strand of an expressed gene.
    Molecular and cellular biology, 1993, Volume: 13, Issue:2

    Topics: Animals; Cell Line, Transformed; Cricetinae; Cricetulus; Deoxyribonuclease HindIII; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Repair; Humans; Kinetics; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1993
Human nucleotide excision nuclease incises synthetic double-stranded DNA containing a pyrimidine dimer at the fourth phosphodiester linkage 3' to the pyrimidine dimer.
    Biochemistry, 1993, Feb-16, Volume: 32, Issue:6

    Topics: Adenosine Triphosphate; Base Sequence; Cell Line; DNA; DNA Damage; DNA Repair; Endodeoxyribonucleases; Escherichia coli Proteins; HeLa Cells; Humans; Kinetics; Magnesium; Molecular Sequence Data; Oligodeoxyribonucleotides; Polydeoxyribonucleotides; Pyrimidine Dimers; Substrate Specificity; Xeroderma Pigmentosum

1993
Gene-specific DNA repair in xeroderma pigmentosum complementation groups A, C, D, and F. Relation to cellular survival and clinical features.
    The Journal of biological chemistry, 1993, Mar-05, Volume: 268, Issue:7

    Topics: Adult; Age Factors; Cell Line; Cell Survival; DNA Repair; Fibroblasts; Genes, myc; Genetic Complementation Test; Globins; Humans; Infant; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Ultraviolet Rays; Xeroderma Pigmentosum

1993
Comparison of the rate of excision of major UV photoproducts in the strands of the human HPRT gene of normal and xeroderma pigmentosum variant cells.
    Mutation research, 1996, Jan-02, Volume: 362, Issue:1

    Topics: Blotting, Southern; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; DNA Replication; Endodeoxyribonucleases; Escherichia coli Proteins; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransferase; Pyrimidine Dimers; Radiation Tolerance; Ultraviolet Rays; Viral Proteins; Xeroderma Pigmentosum

1996
Sister chromatid exchanges in cells defective in mismatch, post-replication and excision repair.
    Mutagenesis, 1995, Volume: 10, Issue:5

    Topics: Caffeine; Cell Line; Colorectal Neoplasms, Hereditary Nonpolyposis; DNA Damage; DNA Repair; DNA Replication; Humans; Pyrimidine Dimers; Sister Chromatid Exchange; Ultraviolet Rays; Xeroderma Pigmentosum

1995
Rodent complementation group 8 (ERCC8) corresponds to Cockayne syndrome complementation group A.
    Mutation research, 1996, Feb-15, Volume: 362, Issue:2

    Topics: Animals; Cell Fusion; Cell Line; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Genetic Complementation Test; Humans; Hybrid Cells; L Cells; Leukemia L5178; Mice; Proteins; Pyrimidine Dimers; Transcription Factors; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1996
Evidence for a novel DNA damage binding protein in human cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1996, Jul-09, Volume: 93, Issue:14

    Topics: Base Sequence; Binding Sites; Cell Cycle; Cell Line; Cell Nucleus; DNA; DNA Damage; DNA-Binding Proteins; Fibroblasts; G1 Phase; Humans; Lymphocytes; Molecular Sequence Data; Molecular Weight; Oligodeoxyribonucleotides; Pyrimidine Dimers; S Phase; Substrate Specificity; Ultraviolet Rays; Xeroderma Pigmentosum

1996
Replication fork bypass of a pyrimidine dimer blocking leading strand DNA synthesis.
    The Journal of biological chemistry, 1997, May-23, Volume: 272, Issue:21

    Topics: Catalysis; DNA Damage; DNA Replication; DNA Restriction Enzymes; Electrophoresis, Gel, Two-Dimensional; HeLa Cells; Humans; In Vitro Techniques; Models, Genetic; Plasmids; Pyrimidine Dimers; Simian virus 40; Xeroderma Pigmentosum

1997
Cyclobutane pyrimidine dimers are the main mutagenic DNA photoproducts in DNA repair-deficient trichothiodystrophy cells.
    Cancer research, 1998, Jan-01, Volume: 58, Issue:1

    Topics: Base Sequence; Cells, Cultured; DNA Repair; Genetic Vectors; Hair Diseases; Humans; Light; Molecular Sequence Data; Point Mutation; Pyrimidine Dimers; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1998
Excision-repair patch lengths are similar for transcription-coupled repair and global genome repair in UV-irradiated human cells.
    Mutation research, 1997, Volume: 385, Issue:2

    Topics: Cell Line; DNA; DNA Repair; Fibroblasts; Fibrosarcoma; Humans; Molecular Weight; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Tumor Cells, Cultured; Ultraviolet Rays; Xeroderma Pigmentosum

1997
A difference in the pattern of repair in a large genomic region in UV-irradiated normal human and Cockayne syndrome cells.
    Mutation research, 1997, Volume: 385, Issue:2

    Topics: Actins; Cell Line; Cockayne Syndrome; DNA; DNA Damage; DNA Probes; DNA Repair; Fibroblasts; Genome; Humans; Insulin; Pyrimidine Dimers; Ultraviolet Rays; X Chromosome; Xeroderma Pigmentosum

1997
Three-dimensional visualization of ultraviolet-induced DNA damage and its repair in human cell nuclei.
    The Journal of investigative dermatology, 1998, Volume: 110, Issue:2

    Topics: Cell Nucleus; Cells, Cultured; DNA Damage; DNA Repair; Enzyme-Linked Immunosorbent Assay; Fibroblasts; Fluorescent Antibody Technique; Humans; Image Processing, Computer-Assisted; Kinetics; Pyrimidine Dimers; Reference Values; Ultraviolet Rays; Xeroderma Pigmentosum

1998
Defective global genome repair in XPC mice is associated with skin cancer susceptibility but not with sensitivity to UVB induced erythema and edema.
    The Journal of investigative dermatology, 1998, Volume: 110, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; DNA Repair; Dose-Response Relationship, Radiation; Edema; Erythema; Genetic Predisposition to Disease; Genome; Mice; Mice, Knockout; Photosensitivity Disorders; Pyrimidine Dimers; Radiation Injuries, Experimental; Skin Neoplasms; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1998
Defective bypass replication of a leading strand cyclobutane thymine dimer in xeroderma pigmentosum variant cell extracts.
    Cancer research, 1998, Jun-01, Volume: 58, Issue:11

    Topics: Cell-Free System; Deoxyribonucleases, Type II Site-Specific; Dimerization; DNA Damage; DNA Replication; HeLa Cells; Humans; Mutagenesis; Pyrimidine Dimers; Thymine; Time Factors; Ultraviolet Rays; Xeroderma Pigmentosum

1998
Mutational analysis of a function of xeroderma pigmentosum group A (XPA) protein in strand-specific DNA repair.
    Nucleic acids research, 1998, Oct-15, Volume: 26, Issue:20

    Topics: Cell Line; Cell Survival; DNA Repair; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Humans; Kinetics; Mutagenesis, Site-Directed; Pyrimidine Dimers; Substrate Specificity; Tetrahydrofolate Dehydrogenase; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

1998
Expression and nucleotide excision repair of a UV-irradiated reporter gene in unirradiated human cells.
    Mutation research, 1999, Mar-10, Volume: 433, Issue:2

    Topics: Cell Line; DNA Repair; Genes, Reporter; Humans; Lac Operon; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1999
The relative expression of mutated XPB genes results in xeroderma pigmentosum/Cockayne's syndrome or trichothiodystrophy cellular phenotypes.
    Human molecular genetics, 1999, Volume: 8, Issue:6

    Topics: Cell Line, Transformed; Child; Child, Preschool; Cockayne Syndrome; DNA; DNA Helicases; DNA Repair; DNA-Binding Proteins; DNA, Complementary; Gene Expression Regulation; Hair Diseases; Humans; Male; Middle Aged; Mutation; Pyrimidine Dimers; Recombinant Fusion Proteins; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1999
Xeroderma pigmentosum variant (XP-V) correcting protein from HeLa cells has a thymine dimer bypass DNA polymerase activity.
    The EMBO journal, 1999, Jun-15, Volume: 18, Issue:12

    Topics: Aphidicolin; Base Sequence; Cell Extracts; Cells, Cultured; Deoxyadenine Nucleotides; Dideoxynucleotides; DNA Damage; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Ethylmaleimide; Fibroblasts; Genetic Complementation Test; HeLa Cells; Humans; Magnesium Chloride; Nucleic Acid Synthesis Inhibitors; Plasmids; Proliferating Cell Nuclear Antigen; Pyrimidine Dimers; Replication Origin; Simian virus 40; Thymine Nucleotides; Xeroderma Pigmentosum

1999
Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription.
    Nucleic acids research, 1999, Jul-15, Volume: 27, Issue:14

    Topics: Adenosine Deaminase; Cell Survival; Cells, Cultured; Cockayne Syndrome; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Genetic Complementation Test; Humans; Pyrimidine Dimers; Radiation Tolerance; RNA; Time Factors; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1999
hRAD30 mutations in the variant form of xeroderma pigmentosum.
    Science (New York, N.Y.), 1999, Jul-09, Volume: 285, Issue:5425

    Topics: Alleles; Amino Acid Sequence; Cell Line; DNA Damage; DNA Polymerase iota; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; DNA, Complementary; Frameshift Mutation; Humans; Molecular Sequence Data; Mutation; Neoplasms, Radiation-Induced; Protein Biosynthesis; Pyrimidine Dimers; Saccharomyces cerevisiae; Sequence Alignment; Sequence Deletion; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1999
Stopping DNA replication in its tracks.
    Science (New York, N.Y.), 1999, Jul-09, Volume: 285, Issue:5425

    Topics: Cloning, Molecular; DNA Damage; DNA Polymerase iota; DNA Repair; DNA Replication; DNA-Binding Proteins; DNA-Directed DNA Polymerase; Humans; Mutation; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1999
Measuring the formation and repair of UV photoproducts by ligation-mediated PCR.
    Methods in molecular biology (Clifton, N.J.), 1999, Volume: 113

    Topics: Base Sequence; Deoxyribodipyrimidine Photo-Lyase; Deoxyribonuclease (Pyrimidine Dimer); DNA; DNA Damage; DNA Primers; DNA-Directed DNA Polymerase; Electrophoresis, Agar Gel; Endodeoxyribonucleases; Escherichia coli; Humans; Polymerase Chain Reaction; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1999
A newly identified patient with clinical xeroderma pigmentosum phenotype has a non-sense mutation in the DDB2 gene and incomplete repair in (6-4) photoproducts.
    The Journal of investigative dermatology, 1999, Volume: 113, Issue:2

    Topics: Caffeine; Codon, Nonsense; DNA Repair; DNA Replication; DNA-Binding Proteins; Female; Frameshift Mutation; Humans; Kinetics; Middle Aged; Phenotype; Photosensitivity Disorders; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1999
The xeroderma pigmentosum group C gene leads to selective repair of cyclobutane pyrimidine dimers rather than 6-4 photoproducts.
    Proceedings of the National Academy of Sciences of the United States of America, 2000, Feb-29, Volume: 97, Issue:5

    Topics: Animals; Cell Line; DNA Damage; DNA Repair; DNA-Binding Proteins; Gene Expression; Humans; Pyrimidine Dimers; Xeroderma Pigmentosum

2000
Fidelity of human DNA polymerase eta.
    The Journal of biological chemistry, 2000, Mar-17, Volume: 275, Issue:11

    Topics: Deoxyribonucleotides; DNA Damage; DNA Polymerase iota; DNA Replication; DNA-Directed DNA Polymerase; Humans; Mutation; Pyrimidine Dimers; Recombinant Proteins; Thymidine; Xeroderma Pigmentosum

2000
Respective roles of cyclobutane pyrimidine dimers, (6-4)photoproducts, and minor photoproducts in ultraviolet mutagenesis of repair-deficient xeroderma pigmentosum A cells.
    Cancer research, 2000, Mar-15, Volume: 60, Issue:6

    Topics: Base Sequence; Cell Line, Transformed; DNA; DNA Mutational Analysis; DNA Repair; Enzyme-Linked Immunosorbent Assay; Genes, Suppressor; Humans; Molecular Sequence Data; Mutagenesis; Mutation; Plasmids; Point Mutation; Pyrimidine Dimers; RNA, Transfer; Sequence Homology, Nucleic Acid; Ultraviolet Rays; Xeroderma Pigmentosum

2000
A molecular pathway for UV-induced CC to TT mutations.
    Mutation research, 2000, Feb-14, Volume: 447, Issue:2

    Topics: DNA Repair; Genes, p53; Humans; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

2000
RPA stabilizes the XPA-damaged DNA complex through protein-protein interaction.
    Biochemistry, 2000, May-30, Volume: 39, Issue:21

    Topics: Base Sequence; Biotinylation; DNA Damage; DNA Repair; DNA Replication; DNA-Binding Proteins; DNA, Single-Stranded; Humans; Kinetics; Molecular Sequence Data; Oligodeoxyribonucleotides; Pyrimidine Dimers; Replication Protein A; Surface Plasmon Resonance; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2000
Complementation of defective translesion synthesis and UV light sensitivity in xeroderma pigmentosum variant cells by human and mouse DNA polymerase eta.
    Nucleic acids research, 2000, 07-01, Volume: 28, Issue:13

    Topics: Amino Acid Sequence; Animals; Cell Division; Cell Line; Cell Survival; Cloning, Molecular; DNA Polymerase iota; DNA Replication; DNA-Directed DNA Polymerase; Gene Expression Profiling; Gene Expression Regulation, Enzymologic; Genetic Complementation Test; Genetic Variation; Humans; Mice; Molecular Sequence Data; Mutation; Pyrimidine Dimers; Radiation Tolerance; RNA, Messenger; Sequence Alignment; Sequence Homology, Amino Acid; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

2000
Xeroderma pigmentosum p48 gene enhances global genomic repair and suppresses UV-induced mutagenesis.
    Molecular cell, 2000, Volume: 5, Issue:4

    Topics: Animals; Cell Line; Cell Transformation, Neoplastic; Cricetinae; Disease Models, Animal; Disease Susceptibility; DNA Repair; DNA-Binding Proteins; Humans; Hypoxanthine Phosphoribosyltransferase; Mice; Mutagenesis; Pyrimidine Dimers; Rodentia; Species Specificity; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

2000
The spectrum of mitochondrial DNA deletions is a ubiquitous marker of ultraviolet radiation exposure in human skin.
    The Journal of investigative dermatology, 2000, Volume: 115, Issue:4

    Topics: Biomarkers; DNA, Mitochondrial; Gene Deletion; Genetic Complementation Test; Humans; Mutation; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

2000
Requirement of DNA polymerase eta for error-free bypass of UV-induced CC and TC photoproducts.
    Molecular and cellular biology, 2001, Volume: 21, Issue:1

    Topics: Alleles; Base Sequence; Cell Division; DNA Damage; DNA-Directed DNA Polymerase; Gene Deletion; Humans; Mutagenesis; Pyrimidine Dimers; Sequence Analysis, DNA; Ultraviolet Rays; Xeroderma Pigmentosum; Yeasts

2001
Protective effects of sunscreening agents on photocarcinogenesis, photoaging, and DNA damage in XPA gene knockout mice.
    Archives of dermatological research, 2000, Volume: 292, Issue:10

    Topics: Aging; Animals; Disease Models, Animal; DNA-Binding Proteins; Ear; Fluorescent Antibody Technique; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunscreening Agents; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2000
A single (6-4) photoproduct inhibits plasmid DNA replication in xeroderma pigmentosum variant cell extracts.
    Environmental and molecular mutagenesis, 2001, Volume: 38, Issue:1

    Topics: Base Sequence; Cell Extracts; Deoxyribonucleases, Type II Site-Specific; DNA; DNA Replication; Electrophoresis, Agar Gel; In Vitro Techniques; Plasmids; Pyrimidine Dimers; Xeroderma Pigmentosum

2001
The relationship between pyrimidine dimers and replicating DNA in UV-irradiated human fibroblasts.
    Nucleic acids research, 1979, Dec-11, Volume: 7, Issue:7

    Topics: Cells, Cultured; DNA Replication; Endonucleases; Fibroblasts; Humans; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1979
Repair of UV-endonuclease-susceptible sites in the 7 complementation groups of xeroderma pigmentosum A through G.
    Mutation research, 1979, Volume: 62, Issue:2

    Topics: Cell Line; DNA; DNA Repair; Genetic Variation; Humans; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1979
[Mechanisms of DNA repair in mammalian cells].
    Tsitologiia, 1977, Volume: 19, Issue:11

    Topics: Animals; Cell Line; Cricetinae; DNA; DNA Ligases; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; DNA, Single-Stranded; Endonucleases; Fibroblasts; Gamma Rays; HeLa Cells; Humans; Mice; Mutagens; Pyrimidine Dimers; Skin; Ultraviolet Rays; Xeroderma Pigmentosum

1977
Pyrimidine dimer excision in human cells and skin cancer.
    National Cancer Institute monograph, 1978, Issue:50

    Topics: Animals; Cell Line; Cricetinae; DNA Repair; DNA, Neoplasm; Fibroblasts; Humans; Mice; Neoplasms, Experimental; Pyrimidine Dimers; Skin Neoplasms; Time Factors; Ultraviolet Rays; Xeroderma Pigmentosum

1978
DNA repair mechanisms.
    Nature, 1978, Jun-29, Volume: 273, Issue:5665

    Topics: Adenosine Triphosphate; Animals; Ataxia Telangiectasia; DNA Repair; DNA Replication; Eukaryotic Cells; Fanconi Anemia; Humans; Poly Adenosine Diphosphate Ribose; Prokaryotic Cells; Pyrimidine Dimers; Xeroderma Pigmentosum

1978
Pyrimidine dimer sites associated with the daughter DNA strands in UV-irradiated human fibroblasts.
    Photochemistry and photobiology, 1978, Volume: 27, Issue:3

    Topics: Cells, Cultured; DNA; Fibroblasts; Humans; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1978
DNA repair in xeroderma pigmentosum cells treated with combinations of ultraviolet radiation and N-acetoxy-2-acetylaminofluorene.
    Cancer research, 1979, Volume: 39, Issue:2 Pt 1

    Topics: Acetoxyacetylaminofluorene; Bromodeoxyuridine; Cell Line; DNA Repair; DNA, Neoplasm; Endonucleases; Fluorenes; Neoplasms, Experimental; Photolysis; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1979
Low-level DNA exchanges in normal human and xeroderma pigmentosum cells after UV irradiation.
    Mutation research, 1977, Volume: 43, Issue:2

    Topics: Cell Line; Coliphages; Deoxyribonucleases; DNA; DNA Repair; Endonucleases; Fibroblasts; Humans; Pyrimidine Dimers; Skin; Ultraviolet Rays; Xeroderma Pigmentosum

1977
Repair of thymine dimers and (6-4) photoproducts in group A xeroderma pigmentosum cell lines harboring a transferred normal chromosome 9.
    Photochemistry and photobiology, 1992, Volume: 56, Issue:3

    Topics: Cell Line; Chromosomes, Human, Pair 9; DNA; DNA Damage; DNA Repair; Humans; Pyrimidine Dimers; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1992
An ultraviolet light-damaged DNA recognition protein absent in xeroderma pigmentosum group E cells binds selectively to pyrimidine (6-4) pyrimidone photoproducts.
    Nucleic acids research, 1992, Nov-11, Volume: 20, Issue:21

    Topics: Base Sequence; DNA; DNA Damage; DNA-Binding Proteins; HeLa Cells; Humans; Molecular Sequence Data; Oligonucleotides; Protein Binding; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1992
Isolation of a DNA endonuclease complex in XPD cells which is defective in ability to incise nucleosomal DNA containing pyrimidine dimers.
    Biochemical and biophysical research communications, 1992, Dec-15, Volume: 189, Issue:2

    Topics: Cell Line; Chromatin; Chromatography, Ion Exchange; DNA; DNA Repair; Endodeoxyribonucleases; Histones; Humans; Isoelectric Focusing; Lymphocytes; Nucleosomes; Plasmids; Pyrimidine Dimers; Substrate Specificity; Ultraviolet Rays; Xeroderma Pigmentosum

1992
Xeroderma pigmentosum complementation group C cells remove pyrimidine dimers selectively from the transcribed strand of active genes.
    Molecular and cellular biology, 1991, Volume: 11, Issue:8

    Topics: Adenosine Deaminase; Base Sequence; Cell Line; DNA; DNA Transposable Elements; Fibroblasts; Genes; Genetic Complementation Test; Humans; Molecular Sequence Data; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1991
Enhancement of ultraviolet-DNA repair in denV gene transfectants and T4 endonuclease V-liposome recipients.
    Photochemistry and photobiology, 1991, Volume: 54, Issue:5

    Topics: Animals; Cell Line, Transformed; Cell Survival; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; Dose-Response Relationship, Radiation; Endodeoxyribonucleases; Fibroblasts; Gene Expression; Humans; Liposomes; Pyrimidine Dimers; RNA, Messenger; Simian virus 40; Transfection; Ultraviolet Rays; Viral Proteins; Xeroderma Pigmentosum

1991
Evidence for defective repair of cyclobutane pyrimidine dimers with normal repair of other DNA photoproducts in a transcriptionally active gene transfected into Cockayne syndrome cells.
    Mutation research, 1991, Volume: 255, Issue:3

    Topics: Cell Line; Chloramphenicol O-Acetyltransferase; Cockayne Syndrome; Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Repair; Escherichia coli; Genome, Human; Humans; Plasmids; Pyrimidine Dimers; Transcription, Genetic; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1991
Cyclobutane dimers and (6-4) photoproducts in human cells are mended with the same patch sizes.
    Photochemistry and photobiology, 1991, Volume: 54, Issue:3

    Topics: Cell Line; Cell Line, Transformed; Cell Nucleus; DNA; DNA Repair; Humans; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Ultraviolet Rays; Xeroderma Pigmentosum

1991
Effects of microinjected photoreactivating enzyme on thymine dimer removal and DNA repair synthesis in normal human and xeroderma pigmentosum fibroblasts.
    Cancer research, 1990, Mar-15, Volume: 50, Issue:6

    Topics: Cells, Cultured; Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Kinetics; Lyases; Microinjections; Pyrimidine Dimers; Reference Values; Ultraviolet Rays; Xeroderma Pigmentosum

1990
Rapid repair kinetics of pyrimidine(6-4)pyrimidone photoproducts in human cells are due to excision rather than conformational change.
    Nucleic acids research, 1990, Feb-25, Volume: 18, Issue:4

    Topics: Cell Line; DNA; DNA Repair; Dose-Response Relationship, Radiation; Endodeoxyribonucleases; Humans; Hydrolysis; Isomerism; Kinetics; Multienzyme Complexes; N-Glycosyl Hydrolases; Nucleic Acid Conformation; Plasmids; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1990
Selective repair of specific chromatin domains in UV-irradiated cells from xeroderma pigmentosum complementation group C.
    Mutation research, 1990, Volume: 235, Issue:3

    Topics: Actins; Blotting, Southern; Cells, Cultured; Chromatin; Deoxyribonuclease EcoRI; DNA; DNA Repair; Humans; Mutation; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Xeroderma Pigmentosum

1990
The role of the nuclear matrix in DNA repair.
    Progress in clinical and biological research, 1990, Volume: 340A

    Topics: Adenosine Deaminase; Cells, Cultured; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; Fibroblasts; Genes; Humans; Nuclear Matrix; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1990
A sensitive, enzymatic assay for the detection of closely opposed cyclobutyl pyrimidine dimers induced in human diploid fibroblasts.
    Mutation research, 1986, Volume: 166, Issue:2

    Topics: Cells, Cultured; DNA Damage; DNA Glycosylases; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Kinetics; N-Glycosyl Hydrolases; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Mitomycin C-induced postmitotic fibroblasts retain the capacity to repair pyrimidine photodimers formed after UV-irradiation.
    Mutation research, 1989, Volume: 219, Issue:4

    Topics: Cell Differentiation; Cells, Cultured; Chromatography, High Pressure Liquid; DNA; DNA Repair; Fibroblasts; Humans; Mitomycin; Mitomycins; Mitosis; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1989
Establishment and characterization of a melanoma cell line from a xeroderma pigmentosum patient: activation of N-ras at a potential pyrimidine dimer site.
    Cancer research, 1989, Mar-01, Volume: 49, Issue:5

    Topics: Animals; Child; Chromosome Aberrations; DNA Repair; Genes, ras; Humans; Melanoma; Mice; Mutation; Phenotype; Pyrimidine Dimers; Skin Neoplasms; Tumor Cells, Cultured; Ultraviolet Rays; Xeroderma Pigmentosum

1989
Evidence that xeroderma pigmentosum cells from complementation group E are deficient in a homolog of yeast photolyase.
    Molecular and cellular biology, 1989, Volume: 9, Issue:11

    Topics: Amino Acid Sequence; Cell Nucleus; Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Damage; DNA Repair; DNA-Binding Proteins; Electrophoresis, Polyacrylamide Gel; HeLa Cells; Humans; Lyases; Magnesium; Molecular Sequence Data; Mutation; Pyrimidine Dimers; Recombination, Genetic; Saccharomyces cerevisiae; Ultraviolet Rays; Xeroderma Pigmentosum

1989
Excision repair characteristics of denV-transformed xeroderma pigmentosum cells.
    Mutation research, 1989, Volume: 217, Issue:2

    Topics: Cell Line; DNA Repair; Genes, Viral; Humans; Pyrimidine Dimers; Transformation, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1989
One pyrimidine dimer inactivates expression of a transfected gene in xeroderma pigmentosum cells.
    Proceedings of the National Academy of Sciences of the United States of America, 1985, Volume: 82, Issue:19

    Topics: Acetyltransferases; Ataxia Telangiectasia; Bacterial Proteins; Cell Line; Cell Transformation, Viral; Chloramphenicol O-Acetyltransferase; DNA Repair; DNA, Recombinant; Fibroblasts; Humans; Hypoxanthine Phosphoribosyltransferase; Lesch-Nyhan Syndrome; Pentosyltransferases; Plasmids; Promoter Regions, Genetic; Pyrimidine Dimers; Recombinant Proteins; Retinoblastoma; Simian virus 40; Transcription, Genetic; Transformation, Genetic; Xeroderma Pigmentosum

1985
Formation and repair of psoralen-DNA adducts and pyrimidine dimers in human DNA and chromatin.
    Environmental health perspectives, 1985, Volume: 62

    Topics: Cell Line; Cells, Cultured; Chromatin; DNA; DNA Repair; Endonucleases; Fibroblasts; Furocoumarins; Humans; Kinetics; Pyrimidine Dimers; Single-Strand Specific DNA and RNA Endonucleases; Skin; Ultraviolet Rays; Xeroderma Pigmentosum

1985
The Fritz-Lipmann lecture. DNA repair in human cells. Biochemistry of the hereditary diseases Fanconi's anaemia and Cockayne syndrome.
    European journal of biochemistry, 1987, Jun-01, Volume: 165, Issue:2

    Topics: Acetyltransferases; Anemia, Aplastic; Chloramphenicol O-Acetyltransferase; Cockayne Syndrome; DNA; DNA Repair; Dwarfism; Fanconi Anemia; Fibroblasts; Humans; NAD; Poly(ADP-ribose) Polymerases; Pyrimidine Dimers; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1987
Unique DNA repair properties of a xeroderma pigmentosum revertant.
    Molecular and cellular biology, 1987, Volume: 7, Issue:9

    Topics: 4-Nitroquinoline-1-oxide; Cell Line, Transformed; DNA Repair; Humans; Methylnitronitrosoguanidine; Mutation; Pyrimidine Dimers; Sister Chromatid Exchange; Ultraviolet Rays; Xeroderma Pigmentosum

1987
Proximity of repair patches to persistent pyrimidine dimers in DNA of normal human and xeroderma pigmentosum cells.
    Radiation research, 1988, Volume: 116, Issue:2

    Topics: DNA Repair; Fibroblasts; Humans; In Vitro Techniques; Pyrimidine Dimers; Xeroderma Pigmentosum

1988
The relative biological importance of cyclobutane and (6-4) pyrimidine-pyrimidone dimer photoproducts in human cells: evidence from a xeroderma pigmentosum revertant.
    Photochemistry and photobiology, 1988, Volume: 48, Issue:1

    Topics: Cell Line; Cell Survival; DNA Repair; DNA Replication; Humans; Pyrimidine Dimers; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1988
Sunlight-induced pyrimidine dimers in human skin fibroblasts in comparison with dimerization after artificial UV-irradiation.
    Photochemistry and photobiology, 1988, Volume: 48, Issue:3

    Topics: Cell Line; Fibroblasts; Humans; Pyrimidine Dimers; Skin; Sunlight; Ultraviolet Rays; Xeroderma Pigmentosum

1988
Immunochemical determination of an initial step in thymine dimer excision repair in xeroderma pigmentosum variant fibroblasts and biopsy material from the normal population and patients with basal cell carcinoma and melanoma.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Adult; Antibodies, Monoclonal; Carcinoma, Basal Cell; DNA; DNA Repair; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Male; Melanoma; Middle Aged; Mutation; Pyrimidine Dimers; Skin Neoplasms; Xeroderma Pigmentosum

1987
Molecular evidence for cleavage of intradimer phosphodiester linkage as a novel step in excision repair of cyclobutyl pyrimidine photodimers in cultured human cells.
    Journal of cell science. Supplement, 1987, Volume: 6

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; DNA Repair; Fibroblasts; Humans; Models, Biological; Pyrimidine Dimers; Thymidine; Thymidine Monophosphate; Ultraviolet Rays; Xeroderma Pigmentosum

1987
Correction of excision repair in xeroderma pigmentosum by hamster chromosome fragments involves both classes of pyrimidine dimers.
    Somatic cell and molecular genetics, 1987, Volume: 13, Issue:6

    Topics: Animals; Cell Line; Cricetinae; Cricetulus; DNA Repair; Humans; Hybrid Cells; Pyrimidine Dimers; Transfection; Xeroderma Pigmentosum

1987
Xeroderma pigmentosum variant cells are not defective in the repair of (6-4) photoproducts.
    International journal of radiation biology and related studies in physics, chemistry, and medicine, 1987, Volume: 52, Issue:2

    Topics: Cell Line; DNA; DNA Repair; Genetic Variation; Humans; In Vitro Techniques; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1987
Photoreversal-dependent release of thymidine and thymidine monophosphate from pyrimidine dimer-containing DNA excision fragments isolated from ultraviolet-damaged human fibroblasts.
    Biochemistry, 1986, May-06, Volume: 25, Issue:9

    Topics: Adult; Cell Line; Cells, Cultured; Child; DNA; DNA Repair; Female; Fibroblasts; Humans; Pyrimidine Dimers; Radioisotope Dilution Technique; Skin; Thymidine; Thymidine Monophosphate; Thymine Nucleotides; Tritium; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Detection and repair of a UV-induced photosensitive lesion in the DNA of human cells.
    Mutation research, 1986, Volume: 165, Issue:3

    Topics: DNA; DNA Repair; Humans; Photolysis; Pyrimidine Dimers; Spectrum Analysis; Ultraviolet Rays; Xeroderma Pigmentosum

1986
A further definition of characteristics of DNA-excision repair in xeroderma pigmentosum complementation group A strains.
    Mutation research, 1986, Volume: 166, Issue:1

    Topics: Cells, Cultured; DNA; Fibroblasts; Humans; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Repair of closely opposed cyclobutyl pyrimidine dimers in UV-sensitive human diploid fibroblasts.
    Mutation research, 1986, Volume: 166, Issue:2

    Topics: Cell Line; Cockayne Syndrome; DNA Glycosylases; DNA Repair; Fanconi Anemia; Humans; Keratosis; Kinetics; N-Glycosyl Hydrolases; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Inhibition of human excision DNA repair by inorganic arsenic and the co-mutagenic effect in V79 Chinese hamster cells.
    Mutation research, 1986, Volume: 172, Issue:1

    Topics: Animals; Arsenic; Cell Survival; Cricetinae; DNA Repair; Drug Synergism; Humans; Mutagens; Mutation; Pyrimidine Dimers; Structure-Activity Relationship; Ultraviolet Rays; Xeroderma Pigmentosum

1986
DNA repair in human xeroderma pigmentosum group C cells involves a different distribution of damaged sites in confluent and growing cells.
    Nucleic acids research, 1986, Oct-24, Volume: 14, Issue:20

    Topics: Cell Cycle; Cells, Cultured; DNA Damage; DNA Repair; DNA Replication; Humans; Pyrimidine Dimers; Xeroderma Pigmentosum

1986
Molecular targets of UVB.
    Current problems in dermatology, 1986, Volume: 15

    Topics: Cell Division; Cells, Cultured; Colony-Forming Units Assay; DNA; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Interphase; Lymphocytes; Melanocytes; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Sister Chromatid Exchange; Skin; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Transient expression of a plasmid gene, a tool to study DNA repair in human cells: defect of DNA repair in Cockayne syndrome; one thymine cyclobutane dimer is sufficient to block transcription.
    European journal of cell biology, 1986, Volume: 39, Issue:2

    Topics: Alkylating Agents; Choline O-Acetyltransferase; Chromosomes, Human; Cockayne Syndrome; Cross-Linking Reagents; DNA; DNA Repair; Dwarfism; Fibroblasts; Gene Expression Regulation; Humans; Plasmids; Pyrimidine Dimers; Transcription, Genetic; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1986
UV stimulation of DNA-mediated transformation of human cells.
    Molecular and cellular biology, 1985, Volume: 5, Issue:4

    Topics: Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Repair; Genes, Dominant; Humans; Pyrimidine Dimers; Recombination, Genetic; Transfection; Transformation, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1985
The induction and repair of DNA damage and its influence on cell death in primary human fibroblasts exposed to UV-A or UV-C irradiation.
    Mutation research, 1985, Volume: 146, Issue:1

    Topics: Cell Survival; Cells, Cultured; DNA; DNA Repair; DNA, Single-Stranded; Fibroblasts; Humans; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1985
(6-4)Photoproducts are removed from the DNA of UV-irradiated mammalian cells more efficiently than cyclobutane pyrimidine dimers.
    Mutation research, 1985, Volume: 143, Issue:3

    Topics: Animals; Cell Line; Cells, Cultured; Cricetinae; Cyclobutanes; DNA Repair; Humans; Mice; Nucleic Acid Denaturation; Photochemistry; Pyrimidine Dimers; Radioimmunoassay; Ultraviolet Rays; Xeroderma Pigmentosum

1985