Page last updated: 2024-08-26

pyrimidine dimers and Skin Neoplasms

pyrimidine dimers has been researched along with Skin Neoplasms in 176 studies

Research

Studies (176)

TimeframeStudies, this research(%)All Research%
pre-199013 (7.39)18.7374
1990's39 (22.16)18.2507
2000's63 (35.80)29.6817
2010's51 (28.98)24.3611
2020's10 (5.68)2.80

Authors

AuthorsStudies
Albrecht, AV; Bohm, KA; Emehiser, RG; Hrdlicka, PJ; Mao, P; Poon, GMK; Roberts, SA; Sivapragasam, S; Stark, B; Wyrick, JJ1
Conigrave, AD; De Silva, WGM; Dixon, KM; Holland, AJA; Mason, RS; Matthews, J; Rybchyn, MS; Yang, C1
Dorr, MM; Rochette, PJ1
Poon, GMK; Selvam, K; Sivapragasam, S; Wyrick, JJ1
Brash, DE; Han, L; Knight, J; Kornacker, K; Mehta, S; Palmatier, MA; Premi, S; Zhao, D1
Burke, KE; Wang, Y; Wei, H; Zhou, X1
Hung, KF; Kawasumi, M; Lee, JW; Ratnakumar, K; Rokunohe, D1
Mao, P; Wyrick, JJ1
Frigola, J; Gonzalez-Perez, A; Lopez-Bigas, N; Sabarinathan, R1
Emri, G; Fidrus, E; Hegedűs, C; Janka, EA; Paragh, G; Remenyik, É1
De Silva, WGM; Dixon, KM; Gordon-Thomson, C; Halliday, GM; Mason, RS; McCarthy, BY; Reeve, VE; Rybchyn, MS; Tongkao-On, W; Yang, C1
Gutierrez-Bayona, NE; Lu, C; Taylor, JS1
Bérubé, R; Douki, T; Drigeard Desgarnier, MC; Lechasseur, A; Rochette, PJ1
Balbo Pogliano, C; Garajovà, Z; Gatti, M; Naegeli, H; Penengo, L; Rüthemann, P1
Duoji, G; Grigalavicius, M; Jie, D; Juzeniene, A; Pudroma, X1
Baker, R; Diffey, BL; Fajuyigbe, D; Lwin, SM; Sarkany, RPE; Tobin, DJ; Young, AR1
Cadet, J; Douki, T1
Baczynska, K; Chlebna-Sokol, D; Harrison, GI; Heydenreich, J; Lesiak, A; Narbutt, J; Olsen, P; Pearson, A; Philipsen, PA; Rogowski-Tylman, M; Sandberg Liljendahl, T; Segerbäck, D; Wulf, HC; Young, AR1
Braun, SA; Bruhs, A; Douki, T; Esser, C; Frauenstein, K; Haarmann-Stemmann, T; Homey, B; Kaveh, M; Krutmann, J; Meller, S; Mescher, M; Pollet, M; Schwarz, A; Shaik, S; Sondenheimer, K; Tigges, J; Vogel, CFA1
Mullenders, LHF1
Beesetti, S; Rayala, SK; Surabhi, RP; Venkatraman, G1
Brown, AJ; Mao, P; Roberts, SA; Smerdon, MJ; Wyrick, JJ1
Boström, M; Clausen, AR; Elliott, K; Filges, S; Larsson, E; Lindberg, M; Ståhlberg, A; Van den Eynden, J1
Lim, HW; Yeager, DG1
Chen, Y; Sugiyama, T1
Ibuki, Y; Toyooka, T; Zhao, X1
Basagaña, X; Dadvand, P; Harrison, GI; Heydenreich, J; Liljendahl, TS; Nieuwenhuijsen, MJ; Olsen, P; Petersen, B; Philipsen, PA; Schmalwieser, AW; Segerbäck, D; Thieden, E; Triguero-Mas, M; Wulf, HC; Young, AR1
Taylor, JS1
Bacchiocchi, A; Bechara, EJ; Brash, DE; Douki, T; Halaban, R; Mano, CM; Premi, S; Wakamatsu, K; Wallisch, S; Weiner, AB1
Abdel-Malek, ZA; Cassidy, P1
Altabas, K; Altabas, V; Carducci, M; De Marco, G; Emanuele, E; Lovati, S; Pavone, PS1
He, YY; Qiang, L; Sample, A; Shah, P; Yang, S; Zhao, B1
Costa, ET; Espinha, G; Forti, FL; Osaki, JH1
Brash, DE1
Blasiak, J; Pawlowska, E; Wysokinski, D1
Brash, DE; Premi, S1
Berry, JL; Cooke, MS; de Gruijl, FR; Felton, SJ; Kift, R; Lam, PM; Rhodes, LE; Vail, A; Webb, AR1
Mao, P; Roberts, SA; Smerdon, MJ; Wyrick, JJ1
Kang, TH; Park, JM1
Chen, GS; Hou, PS; Huang, SM; Lai, HC; Lan, CE; Peng, YT; Wu, CH; Wu, CS; Yang, HJ1
Ellison, TI; Gilliam, AC; MacDonald, PN; Smith, MK1
Burch, JA; Hall, RP; Iannacchione, MA; Murray, JC; Pinnell, SR; Streilein, RD1
Hemminki, K; Segerbäck, D; Snellman, E; Strozyk, M1
Alekseev, S; Backendorf, C; de Gruijl, FR; Jansen, JG; Mullenders, LH; Pines, A; Vrieling, H1
Barros, SB; da Silva, VV; de Almeida, RL; Miranda, DV; Rivelli, DP; Ropke, CD; Sawada, TC1
Kay, E; Leader, M; Mabruk, MJ; Murphy, GM; Murphy, M; Toh, LK1
Fahey, P; Hacker, E; Hayward, N; Muller, HK; Walker, G1
Broyde, S; Patel, DJ1
Aggarwal, AK; Jain, R; Johnson, RE; Prakash, L; Prakash, S; Silverstein, TD1
Johnson, JL; Lloyd, RS; Lowell, BC; McCullough, AK; Ryabinina, OP1
Fernandez, AA; Mitchell, DL1
Rünger, TM1
Esser, PR; Lademann, J; Martin, SF; Schempp, CM; Simon-Haarhaus, B; Wölfle, U1
Beani, JC; Bourrain, JL; Douki, T; Leccia, MT; Mouret, S1
Fishelevich, R; Gaspari, AA; Lee, J; Liu, H; Meng, TC; Nakazono, A; Tammaro, A; Tuchinda, P; Zhao, Y1
Besaratinia, A; Pfeifer, GP1
Baldea, I; Bolfa, P; Catoi, C; Clichici, S; Daicoviciu, D; Filip, A; Gal, A; Gherman, C; Muresan, A; Postescu, ID1
Sarkany, RP; Tewari, A; Young, AR1
Agarwal, C; Agarwal, R; Deep, G; Roy, S1
Abdel-Daim, M; Funasaka, Y; Kawana, S; Nishigori, C1
Galloway, DA; Howie, HL; Robinson, K; Wallace, NA1
Kotova, N; Liljendahl, TS; Segerbäck, D1
Carati, D; Castellana, D; D'Amore, M; De Lucro, R; La Pesa, V; Lisi, S; Lofrumento, DD; Sisto, M; Zuccarello, V1
Grage, MM; Harrison, GI; Sarkany, R; Tewari, A; Young, AR1
Bernerd, F; Del Bino, S1
Andersson, EM; Barregard, L; Blomqvist, A; Liljendahl, TS; Segerbäck, D1
Damian, DL; Halliday, GM; Surjana, D1
Lebwohl, M; Wang, Y; Wei, H; Zhang, X1
Bäckvall, H; Berne, B; Ponten, F; Wassberg, C1
Alberts, D; Bair, WB; Bowden, GT; Dong, Z; Einspahr, J; Hart, N; Liu, G1
Bates, SE; Bouziane, M; O'Connor, TR; Sarasin, A; Stary, A; Zhou, NY1
Reardon, JT; Sancar, A2
Bhawan, J; Gilchrest, BA; Goukassian, DA; Helms, E; van Oostrom, C; van Steeg, H1
Agarwal, R; Dhanalakshmi, S; Mallikarjuna, GU; Singh, RP1
Andrew, SE; Campbell, MR; Thulien, KJ; Tron, VA; Young, LC1
Horio, T; Itoh, T; Kunisada, T; Matsumura, Y; Miyauchi-Hashimoto, H; Okamoto, H; Tanaka, K; Yamazaki, F1
Yarosh, DB1
Lima-Bessa, KM; Menck, CF1
de Gruijl, FR; Eker, AP; Hoeijmakers, JH; Jans, J; Nakajima, S; Rebel, H; Rijksen, Y; Schul, W; Sert, YG; van der Horst, GT; van Steeg, H; Yasui, A1
Besaratinia, A; Pfeifer, GP; You, YH1
Agarwal, R; Dhanalakshmi, S; Gu, M; Singh, RP1
Horio, T; Itoh, T; Miyauchi-Hashimoto, H; Sugihara, A; Tanaka, K1
Alekseev, S; Backendorf, C; de Gruijl, FR; Fousteri, M; Kool, H; Moser, J; Mullenders, LH; Rebel, H; Vrieling, H1
Brown, DA; Canning, MT; Nay, SL; Pena, AV; Yarosh, DB1
Iizuka, H; Ishida-Yamamoto, A; Nakajima, S; Sakata, I; Takahashi, H1
Gao, D; Lebwohl, M; Moore, JO; Phelps, R; Stebbins, WG; Wang, Y; Wei, H; Zhou, X1
Beissert, S; Kojima, M; Maeda, A; Schneider, SW; Schwarz, A; Schwarz, T1
Garinis, GA; Jans, J; van der Horst, GT1
Essen, LO; Klar, T1
Conney, AH; Lin, Y; Lou, YR; Lu, YP; Peng, QY; Shih, WJ; Xie, JG; Zhou, S1
Calcagnile, A; D'Errico, M; Dogliotti, E; Lemma, T; Proietti De Santis, L1
Mitchell, D1
de Gruijl, FR; Garinis, GA; Hoeijmakers, JH; Jans, J; Leenen, PJ; Moorhouse, M; Rijksen, Y; Schul, W; Sert, YG; Smid, M; van der Horst, GT; van der Spek, PJ; van der Velde, A; van Oudenaren, A; Yasui, A1
de Gruijl, FR; Mitchell, DL; Mulder, AA; Mullenders, LH; Nijhof, JG; van Pelt, C1
Béani, JC; Cadet, J; Douki, T; Favier, A; Leccia, MT; Mouret, S1
Gaube, S; Gilbertz, KP; Kerkmann, U; Placzek, M; Przybilla, B1
Ishizaki, K; Kumimoto, H; Kunisada, M; Nakabeppu, Y; Nishigori, C; Sakumi, K1
Arad, S; Epstein, EH; Gilchrest, BA; Goukassian, DA; Hebert, J; Zattra, E1
Cafardi, JA; Elmets, CA1
Kripke, ML1
DiPaolo, JA; Doniger, J; Jacobson, ED; Krell, K1
Granstein, RD; Sober, AJ1
Berg, RJ; de Gruijl, FR; de Laat, A; Roza, L; van der Leun, JC1
Epe, B; Möller, K; Rünger, TM1
Bourre, F; Chevallier-Lagente, O; Eker, AP; Eveno, E; Hoeijmakers, JH; Kleijer, WJ; Nikaido, O; Quilliet, X; Roza, L; Stefanini, M1
Baan, RA; Berg, RJ; de Gruijl, FR; Lohman, PH; Roza, L; Vink, AA1
Bergman, W; Darroudi, F; Noz, KC; Roza, L; Schothorst, AA1
Pfeifer, GP; Tornaletti, S2
Pfeifer, GP; Rozek, D; Tornaletti, S1
Kripke, ML; Yarosh, DB1
Calcagnile, A; D'errico, M; Dogliotti, E1
Hattori, Y; Hiai, H; Imamura, S; Nikaido, O; Nishigori, C; Osawa, T; Tanaka, T; Toyokuni, S; Uchida, K1
Sutherland, BM1
Cleaver, JE1
Ahrens, C; Arlett, CF; Krutmann, J; Roza, L1
Agarwal, R; Chatterjee, ML; Mukhtar, H1
Artuso, M; English, DR; Hall, J1
Gao, S; Holmquist, GP1
Hill, HZ; Li, W; Mitchell, DL; Xin, P1
Berton, TR; Fischer, SM; Locniskar, MF; Mitchell, DL1
Denissenko, MF; Pfeifer, GP; Tommasi, S1
Drouin, R; Therrien, JP1
Kvam, E; Tyrrell, RM1
Alberts, D; Barthelman, M; Chen, W; Gensler, HL; Martinez, J1
Bykov, VJ; Hemminki, K; Jansen, CT1
Applegate, LA; Burren, R; Frenk, E; Panizzon, RG; Scaletta, C1
Berg, RJ; de Gruijl, FR; Mullenders, LH; Ruven, HJ; Sands, AT1
Bykov, VJ; Hemminki, K; Lindgren, C; Tobin, D1
Berg, RJ; de Gruijl, FR1
Lloyd, RS1
Dammann, R; Pfeifer, GP; Tu, Y1
Drobetsky, EA; Drouin, R; Rouabhia, M; Therrien, JP1
Brooks, L; Crook, T; Crossland, S; Fraser-Andrews, EA; McGregor, JM; Rozycka, M; Whittaker, SJ1
Liebler, DC; McVean, M1
Johnson, RE; Kondratick, CM; Prakash, L; Prakash, S1
Li, C; Pfeifer, GP; You, YH1
Bykov, VJ; Hemminki, K; Jansen, CT; Snellman, E; Xu, G1
Wallin, H1
Ahmed, NU; Bito, T; Budiyanto, A; Ichihashi, M; Osawa, T; Ueda, M; Wu, A1
Kusewitt, DF; Ley, RD; Reeve, VE1
Ichihashi, M; Kawasaki, K; Reguer, G; Suzuki1, T; Ueda, M; Yamasaki, H1
Hemminki, K; Jansen, CT; Snellman, E; Xu, G1
Meador, JA; Mitchell, DL; Walter, RB1
Birch-Machin, MA; Nikaido, O; Ray, AJ; Rees, JL; Turner, R1
Cooke, MS; Herbert, KE; Ladapo, A; Lunec, J; Mistry, N1
Ahmed, NU; Bito, T; Budiyanto, A; Ichihashi, M; Nikaido, O; Osawa, T; Ueda, M; Wu, A1
Pfeifer, GP; Szabó, PE; You, YH1
Boguhn, O; Breitbart, EW; Greinert, R; Harder, D; Mitchell, DL; Volkmer, B1
Horiki, S; Horio, T; Miyauchi-Hashimoto, H; Nikaido, O; Tanaka, K1
Pfeifer, GP; You, YH1
Barnard, A; Burd, RM; Cooke, MS; Evans, MD; Hutchinson, PE; Lunec, J; Patel, K1
Byrom, M; Chiarello, S; Lowery, MG; Mitchell, DL1
Cadet, J; Douki, T; Pouget, JP; Ravanat, JL; Sauvaigo, S1
Itakura, E; Iwamoto, Y; Nikaido, O; Oda, Y; Oshiro, Y; Sakamoto, A; Tsuneyoshi, M1
Chouinard, N; Drouin, R; Mitchell, DL; Robert, M; Rouabhia, M; Therrien, JP1
Galendo, D; Hergenhahn, M; Hollstein, M; Koomagi, R; Luo, JL; Pfeifer, GP; Tong, WM; Wang, ZQ; Yang, Q; Yoon, JH1
Roza, L; Vink, AA1
Bergamo, BM; Elmets, CA; Katiyar, SK; Vyalil, PK1
Hemminki, K; Jansen, CT; Snellman, E; Zhao, C2
Carrier, WL; Lee, WH; Regan, JD; Smith, DP; Waters, R1
Johnson, BE1
Hori, M; Ihara, M; Koike, K; Udono, MU; Urata, Y; Yoshida, H1
Alas, LG; Citron, M; Kibitel, JT; Mitchell, D; Oberyszyn, A; Rosenstein, R; Spinowitz, A; Yarosh, D; Yee, V1
Applegate, LA; Fry, RJ; Ley, RD; Sanchez, AB1
Alcalay, J; Freeman, SE; Goldberg, LH; Wolf, JE1
Carter, DM1
Bootsma, D; Bos, JL; Hoeijmakers, JH; Keijzer, W; Langeveld, JC; Mulder, MP; Smit, EM1
Strickland, PT2
Boyle, JM; Müller, H; Roth, M1
Mitchell, DL; Nairn, RS1
Jung, EG1
Applegate, LA; Ley, RD; Stuart, TD1

Reviews

34 review(s) available for pyrimidine dimers and Skin Neoplasms

ArticleYear
Deciphering UV-induced DNA Damage Responses to Prevent and Treat Skin Cancer.
    Photochemistry and photobiology, 2020, Volume: 96, Issue:3

    Topics: Ataxia Telangiectasia Mutated Proteins; DNA Damage; DNA Repair; DNA Replication; Humans; Pyrimidine Dimers; Skin; Skin Neoplasms; Transcription, Genetic; Ultraviolet Rays

2020
Molecular Mechanisms of UVA-Induced Melanoma.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2017, Volume: 36, Issue:3

    Topics: DNA Damage; Female; Humans; Male; Melanins; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2017
Formation of UV-induced DNA damage contributing to skin cancer development.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2018, Dec-05, Volume: 17, Issue:12

    Topics: Animals; DNA Adducts; DNA Damage; DNA Repair; Guanine; Humans; Melanins; Proto-Oncogene Mas; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2018
Solar UV damage to cellular DNA: from mechanisms to biological effects.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2018, Dec-05, Volume: 17, Issue:12

    Topics: Animals; DNA Damage; DNA Repair; Humans; Pyrimidine Dimers; Signal Transduction; Skin Neoplasms; Ultraviolet Rays

2018
What's New in Photoprotection: A Review of New Concepts and Controversies.
    Dermatologic clinics, 2019, Volume: 37, Issue:2

    Topics: Antioxidants; Benzophenones; Cholecalciferol; Coral Reefs; Deoxyribodipyrimidine Photo-Lyase; Endocrine Disruptors; Environment; Free Radicals; Humans; Pyrimidine Dimers; Skin Aging; Skin Neoplasms; Sun Protection Factor; Sunburn; Sunlight; Sunscreening Agents; Titanium; Ultraviolet Rays; Vitamins; Zinc Oxide

2019
Nucleotide Excision Repair and Vitamin D--Relevance for Skin Cancer Therapy.
    International journal of molecular sciences, 2016, Apr-06, Volume: 17, Issue:4

    Topics: Animals; DNA Damage; DNA Repair; Humans; Melanoma; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Vitamin D; Vitamins

2016
Chemical excitation of electrons: A dark path to melanoma.
    DNA repair, 2016, Volume: 44

    Topics: DNA Damage; Electrons; Humans; Keratinocytes; Melanins; Melanoma; NADPH Oxidases; Neoplasms, Radiation-Induced; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunlight; Superoxides; Ultraviolet Rays

2016
UV-Induced DNA Damage and Mutagenesis in Chromatin.
    Photochemistry and photobiology, 2017, Volume: 93, Issue:1

    Topics: Chromatin; DNA; DNA Damage; Humans; Mutagenesis; Neoplasms, Radiation-Induced; Nucleosomes; Pyrimidine Dimers; Skin Neoplasms; Transcription Factors; Ultraviolet Rays

2017
Transcriptional and Posttranslational Regulation of Nucleotide Excision Repair: The Guardian of the Genome against Ultraviolet Radiation.
    International journal of molecular sciences, 2016, Nov-04, Volume: 17, Issue:11

    Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Chromosomal Proteins, Non-Histone; DNA Damage; DNA Repair; Guanine Nucleotide Exchange Factors; Humans; Protein Isoforms; Protein Processing, Post-Translational; Pyrimidine Dimers; Signal Transduction; Skin Neoplasms; Transcription, Genetic; Ubiquitin-Protein Ligases; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2016
UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012, Volume: 11, Issue:1

    Topics: DNA Damage; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2012
Effect of chemical peeling on the skin in relation to UV irradiation.
    Experimental dermatology, 2012, Volume: 21 Suppl 1

    Topics: Animals; Chemexfoliation; Humans; Light; Mice; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunburn; Ultraviolet Rays

2012
Thermodynamic cooperativity and kinetic proofreading in DNA damage recognition and repair.
    Cell cycle (Georgetown, Tex.), 2004, Volume: 3, Issue:2

    Topics: DNA Damage; DNA Repair; Humans; Pyrimidine Dimers; Skin Neoplasms; Thermodynamics; Ultraviolet Rays

2004
DNA repair, immunosuppression, and skin cancer.
    Cutis, 2004, Volume: 74, Issue:5 Suppl

    Topics: Animals; Deoxyribodipyrimidine Photo-Lyase; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Repair; Humans; Immune Tolerance; Liposomes; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Viral Proteins

2004
Mutations induced by ultraviolet light.
    Mutation research, 2005, Apr-01, Volume: 571, Issue:1-2

    Topics: 5-Methylcytosine; Animals; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2005
Photolyases: capturing the light to battle skin cancer.
    Future oncology (London, England), 2006, Volume: 2, Issue:2

    Topics: Animals; Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Repair; Mice; Mice, Transgenic; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2006
Light-driven DNA repair by photolyases.
    Cellular and molecular life sciences : CMLS, 2006, Volume: 63, Issue:11

    Topics: Animals; Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Repair; Forecasting; Humans; Light; Models, Biological; Models, Molecular; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2006
Cell type and DNA damage specific response of human skin cells to environmental agents.
    Mutation research, 2007, Jan-03, Volume: 614, Issue:1-2

    Topics: Antioxidants; Apoptosis; Cell Differentiation; Cells, Cultured; DNA Damage; DNA Repair; Fibroblasts; G1 Phase; Humans; Keratinocytes; Oxidants; Pyrimidine Dimers; Skin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2007
T4 endonuclease V: review and application to dermatology.
    Expert opinion on biological therapy, 2008, Volume: 8, Issue:6

    Topics: Administration, Cutaneous; Adult; Animals; Bacteriophage T4; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Clinical Trials as Topic; Deoxyribonuclease (Pyrimidine Dimer); DNA Repair; Drug Evaluation, Preclinical; Female; Genetic Predisposition to Disease; Humans; Liposomes; Male; Middle Aged; Neoplasms, Radiation-Induced; Photosensitivity Disorders; Pyrimidine Dimers; Rats; Skin Neoplasms; Sunburn; Viral Proteins; Xeroderma Pigmentosum

2008
Immunologic mechanisms in UV radiation carcinogenesis.
    Advances in cancer research, 1981, Volume: 34

    Topics: Animals; Antibodies, Neoplasm; Antigens, Neoplasm; DNA; DNA Repair; Graft Rejection; Humans; Immunosuppression Therapy; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Neoplasms, Radiation-Induced; Nucleic Acid Denaturation; Pyrimidine Dimers; Rats; Skin Neoplasms; Sunlight; T-Lymphocytes; T-Lymphocytes, Regulatory; Ultraviolet Rays

1981
Current concepts in ultraviolet carcinogenesis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 170, Issue:2

    Topics: Aging; Animals; Antioxidants; beta Carotene; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carotenoids; DNA; Female; Geography; Humans; Male; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Sex Factors; Skin Neoplasms; Ultraviolet Rays; Vitamin A

1982
DNA repair and cytokines in antimutagenesis and anticarcinogenesis.
    Mutation research, 1996, Feb-19, Volume: 350, Issue:1

    Topics: Cytokines; DNA Damage; DNA Repair; Humans; Immune Tolerance; Melanins; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Virus Activation

1996
Genetic alterations in skin cancer.
    Annali dell'Istituto superiore di sanita, 1996, Volume: 32, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; Cocarcinogenesis; Disease Susceptibility; DNA Damage; DNA Ligases; DNA Repair; Epidermis; Genes, p53; Humans; Mice; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Sunlight; Ultraviolet Rays

1996
UV damage and repair mechanisms in mammalian cells.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 1996, Volume: 18, Issue:3

    Topics: Animals; Chromatin; DNA; DNA Damage; DNA Repair; Humans; In Vitro Techniques; Neoplasms, Radiation-Induced; Photochemistry; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1996
Mutagenic lesions in carcinogenesis: induction and repair of pyrimidine dimers.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:4

    Topics: Animals; DNA Damage; DNA Repair; Humans; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Sunlight

1996
Mutagenic lesions in photocarcinogenesis: the fate of pyrimidine photoproducts in repair-deficient disorders.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:4

    Topics: Animals; DNA Repair; Humans; Mutation; Photobiology; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1996
The role of DNA damage and repair in ultraviolet B radiation-induced immunomodulation: relevance for human photocarcinogenesis.
    Photochemistry and photobiology, 1996, Volume: 63, Issue:4

    Topics: Animals; DNA Damage; DNA Repair; Humans; Immune Tolerance; Intercellular Adhesion Molecule-1; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1996
Molecular epidemiology of skin cancers: DNA repair and non-melanocytic skin cancer.
    Annali dell'Istituto superiore di sanita, 1996, Volume: 32, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cockayne Syndrome; DNA Damage; DNA Repair; Humans; Incidence; Mammals; Neoplasms, Radiation-Induced; Photosensitivity Disorders; Pyrimidine Dimers; Risk Factors; Skin Neoplasms; Sunlight; Ultraviolet Rays; Xeroderma Pigmentosum

1996
Somatic mutation theory, DNA repair rates, and the molecular epidemiology of p53 mutations.
    Mutation research, 1997, Volume: 386, Issue:1

    Topics: Animals; DNA Repair; Genes, p53; Humans; Kinetics; Molecular Epidemiology; Mutagenesis; Mutation; Pyrimidine Dimers; Skin Neoplasms

1997
Melanin: a two edged sword?
    Pigment cell research, 1997, Volume: 10, Issue:3

    Topics: 1-Methyl-3-isobutylxanthine; Animals; Disease Susceptibility; DNA Damage; Humans; Melanins; Melanocyte-Stimulating Hormones; Melanocytes; Melanoma, Experimental; Mice; Mice, Mutant Strains; Neoplasm Proteins; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Racial Groups; Reactive Oxygen Species; Skin Neoplasms; Skin Pigmentation; Sunlight; Ultraviolet Rays

1997
Base excision repair of cyclobutane pyrimidine dimers.
    Mutation research, 1998, Sep-11, Volume: 408, Issue:3

    Topics: Antineoplastic Agents; Base Pairing; Carbon-Oxygen Lyases; Cyclobutanes; Deoxyribonuclease IV (Phage T4-Induced); DNA Glycosylases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; Humans; N-Glycosyl Hydrolases; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1998
Photobiology of Monodelphis domestica.
    Developmental and comparative immunology, 2000, Volume: 24, Issue:5

    Topics: Animals; Cornea; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; DNA Repair; Eye Neoplasms; Melanoma; Mice; Mice, Nude; Opossums; Oxazolone; Photobiology; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Urocanic Acid

2000
Effects of UV and visible radiations on cellular DNA.
    Current problems in dermatology, 2001, Volume: 29

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Biomarkers; Deoxyguanosine; DNA; DNA Adducts; DNA Damage; DNA Ligases; Forecasting; Humans; Light; Neoplasms, Radiation-Induced; Oxidation-Reduction; Oxidative Stress; Photochemistry; Photosensitivity Disorders; Pyrimidine Dimers; Radiation-Sensitizing Agents; Reactive Oxygen Species; Skin Neoplasms; Ultraviolet Rays

2001
Biological consequences of cyclobutane pyrimidine dimers.
    Journal of photochemistry and photobiology. B, Biology, 2001, Dec-31, Volume: 65, Issue:2-3

    Topics: Animals; DNA Damage; Erythema; Humans; Immune Tolerance; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2001
Green tea polyphenols: DNA photodamage and photoimmunology.
    Journal of photochemistry and photobiology. B, Biology, 2001, Dec-31, Volume: 65, Issue:2-3

    Topics: Animals; DNA Damage; Flavonoids; Humans; Immune Tolerance; Phenols; Polymers; Polyphenols; Pyrimidine Dimers; Skin; Skin Neoplasms; Tea; Ultraviolet Rays

2001

Trials

4 trial(s) available for pyrimidine dimers and Skin Neoplasms

ArticleYear
Comparative Effects of Sunscreens Alone vs Sunscreens Plus DNA Repair Enzymes in Patients With Actinic Keratosis: Clinical and Molecular Findings from a 6-Month, Randomized, Clinical Study.
    Journal of drugs in dermatology : JDD, 2015, Volume: 14, Issue:9

    Topics: Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Deoxyribodipyrimidine Photo-Lyase; Drug Combinations; Endonucleases; Female; Humans; Keratosis, Actinic; Male; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunscreening Agents

2015
A topical antioxidant solution containing vitamins C and E stabilized by ferulic acid provides protection for human skin against damage caused by ultraviolet irradiation.
    Journal of the American Academy of Dermatology, 2008, Volume: 59, Issue:3

    Topics: Administration, Cutaneous; Adult; alpha-Tocopherol; Antioxidants; Ascorbic Acid; Coumaric Acids; Cytokines; DNA Damage; DNA Primers; Drug Combinations; Erythema; Humans; Immunohistochemistry; Polymerase Chain Reaction; Pyrimidine Dimers; Radiation Dosage; RNA, Messenger; Skin; Skin Neoplasms; Statistics, Nonparametric; Sunburn; Tumor Suppressor Protein p53; Ultraviolet Rays

2008
Induction and excretion of ultraviolet-induced 8-oxo-2'-deoxyguanosine and thymine dimers in vivo: implications for PUVA.
    The Journal of investigative dermatology, 2001, Volume: 116, Issue:2

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Case-Control Studies; Deoxyguanosine; DNA Damage; Enzyme-Linked Immunosorbent Assay; Female; Humans; Male; Middle Aged; Pilot Projects; Psoriasis; PUVA Therapy; Pyrimidine Dimers; Reproducibility of Results; Skin Neoplasms; Ultraviolet Rays

2001
Excision repair of pyrimidine dimers induced by simulated solar radiation in the skin of patients with basal cell carcinoma.
    The Journal of investigative dermatology, 1990, Volume: 95, Issue:5

    Topics: Adult; Aged; Aged, 80 and over; Carcinoma, Basal Cell; DNA Repair; DNA, Neoplasm; Dose-Response Relationship, Radiation; Female; Humans; Male; Middle Aged; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1990

Other Studies

138 other study(ies) available for pyrimidine dimers and Skin Neoplasms

ArticleYear
CTCF binding modulates UV damage formation to promote mutation hot spots in melanoma.
    The EMBO journal, 2021, 10-18, Volume: 40, Issue:20

    Topics: Binding Sites; Binding, Competitive; CCCTC-Binding Factor; Cell Line, Tumor; DNA Damage; DNA Repair; Gene Expression; Humans; Melanoma; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Serine-Threonine Kinases; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2021
The CaSR Modulator NPS-2143 Reduced UV-Induced DNA Damage in Skh:hr1 Hairless Mice but Minimally Inhibited Skin Tumours.
    International journal of molecular sciences, 2023, Mar-03, Volume: 24, Issue:5

    Topics: Animals; DNA Damage; Female; Humans; Mice; Mice, Hairless; Pyrimidine Dimers; Receptors, Calcium-Sensing; Skin; Skin Neoplasms; Ultraviolet Rays

2023
Reduction of DNA damage repair efficiency and accumulation of residual damage following chronic UVB-irradiation of HaCaT cells.
    PloS one, 2023, Volume: 18, Issue:4

    Topics: DNA Damage; DNA Repair; HaCaT Cells; Humans; Keratinocytes; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2023
Detecting recurrent passenger mutations in melanoma by targeted UV damage sequencing.
    Nature communications, 2023, 05-11, Volume: 14, Issue:1

    Topics: DNA Damage; Humans; Melanocytes; Melanoma; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2023
Genomic sites hypersensitive to ultraviolet radiation.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 11-26, Volume: 116, Issue:48

    Topics: 5' Untranslated Regions; Cells, Cultured; DNA Damage; Fibroblasts; Gene Expression Regulation; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Melanocytes; Melanoma; Mutation; Promoter Regions, Genetic; Protein Biosynthesis; Pyrimidine Dimers; Pyrimidine Nucleotides; Skin Neoplasms; TOR Serine-Threonine Kinases; Ultraviolet Rays

2019
Dietary Lycopene Protects SKH-1 Mice Against Ultraviolet B-Induced Photocarcinogenesis
    Journal of drugs in dermatology : JDD, 2019, 12-01, Volume: 18, Issue:12

    Topics: Animals; Antioxidants; Dietary Supplements; Female; Lycopene; Mice; Mice, Hairless; Proliferating Cell Nuclear Antigen; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2019
Genome-Wide Mapping of UV-Induced DNA Damage with CPD-Seq.
    Methods in molecular biology (Clifton, N.J.), 2020, Volume: 2175

    Topics: Cell Line; Chromosome Mapping; Computational Biology; DNA Damage; Fibroblasts; High-Throughput Nucleotide Sequencing; Humans; Pyrimidine Dimers; Saccharomyces cerevisiae; Skin Neoplasms; Ultraviolet Rays

2020
Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites.
    Nucleic acids research, 2021, 01-25, Volume: 49, Issue:2

    Topics: Binding Sites; Chromosome Mapping; DNA Damage; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Mutagenesis; Mutation; Pyrimidine Dimers; Skin Neoplasms; Transcription Factors; Ultraviolet Rays; Whole Genome Sequencing

2021
Inhibitors of Nucleotide Excision Repair Decrease UVB-Induced Mutagenesis-An In Vitro Study.
    International journal of molecular sciences, 2021, Feb-06, Volume: 22, Issue:4

    Topics: Animals; Arsenic Trioxide; Autophagy; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Transformed; Cell Survival; CHO Cells; Cricetulus; DNA Damage; DNA Repair; HaCaT Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Melanoma; Mutation Rate; Pyrimidine Dimers; Resveratrol; Skin; Skin Neoplasms; Spironolactone; Ultraviolet Rays

2021
Sex Differences in Photoprotective Responses to 1,25-Dihydroxyvitamin D3 in Mice Are Modulated by the Estrogen Receptor-β.
    International journal of molecular sciences, 2021, Feb-16, Volume: 22, Issue:4

    Topics: Administration, Cutaneous; Animals; Calcitriol; Dermatitis, Contact; Disease Models, Animal; Estrogen Receptor beta; Female; Immune Tolerance; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Pyrimidine Dimers; Sex Factors; Signal Transduction; Skin; Skin Neoplasms; Sunburn; Sunscreening Agents; Ultraviolet Rays

2021
The effect of flanking bases on direct and triplet sensitized cyclobutane pyrimidine dimer formation in DNA depends on the dipyrimidine, wavelength and the photosensitizer.
    Nucleic acids research, 2021, 05-07, Volume: 49, Issue:8

    Topics: 3' Flanking Region; 5' Flanking Region; Base Sequence; Cytosine; DNA; Humans; Melanocytes; Mutagenesis; Mutation; Photosensitizing Agents; Pyrimidine Dimers; Skin Neoplasms; Thymine; Ultraviolet Rays

2021
Persistence and Tolerance of DNA Damage Induced by Chronic UVB Irradiation of the Human Genome.
    The Journal of investigative dermatology, 2018, Volume: 138, Issue:2

    Topics: Adult; Biopsy; DNA Damage; DNA Repair; DNA Replication; Dose-Response Relationship, Radiation; Female; Fibroblasts; Genome, Human; Genomic Instability; Heterochromatin; Humans; Primary Cell Culture; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Young Adult

2018
ASH1L histone methyltransferase regulates the handoff between damage recognition factors in global-genome nucleotide excision repair.
    Nature communications, 2017, 11-06, Volume: 8, Issue:1

    Topics: Cell Line; DNA Damage; DNA Repair; DNA-Binding Proteins; HeLa Cells; Histone-Lysine N-Methyltransferase; Histones; Humans; Methylation; Nucleosomes; Protein Interaction Domains and Motifs; Pyrimidine Dimers; RNA, Small Interfering; Skin Neoplasms; Transcription Factors; Ultraviolet Rays

2017
Melanin distribution in human epidermis affords localized protection against DNA photodamage and concurs with skin cancer incidence difference in extreme phototypes.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2018, Volume: 32, Issue:7

    Topics: Adult; Black People; DNA Damage; Epidermis; Humans; Melanins; Pyrimidine Dimers; Skin Neoplasms; Skin Pigmentation; Sunlight; White People

2018
Children sustain high levels of skin DNA photodamage, with a modest increase of serum 25-hydroxyvitamin D
    The British journal of dermatology, 2018, Volume: 179, Issue:4

    Topics: Bathing Beaches; Calcifediol; Child; Diaries as Topic; DNA Damage; Dose-Response Relationship, Radiation; Female; Holidays; Humans; Male; Poland; Pyrimidine Dimers; Seasons; Skin; Skin Neoplasms; Sunbathing; Sunlight; Sunscreening Agents; Ultraviolet Rays

2018
The AHR represses nucleotide excision repair and apoptosis and contributes to UV-induced skin carcinogenesis.
    Cell death and differentiation, 2018, Volume: 25, Issue:10

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; Cell Cycle Checkpoints; Cell Line; Cyclin-Dependent Kinase Inhibitor p27; DNA Breaks, Double-Stranded; DNA Repair; Humans; Keratinocytes; Mice; Mice, Hairless; Mice, Knockout; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Receptors, Aryl Hydrocarbon; RNA Interference; RNA, Small Interfering; Skin Neoplasms; Ultraviolet Rays

2018
Mechanics of PAK1-A new molecular player in the arena of skin cancer.
    Journal of cellular physiology, 2018, Volume: 234, Issue:1

    Topics: Ataxia Telangiectasia Mutated Proteins; Biomarkers, Tumor; DNA Damage; DNA Repair; ErbB Receptors; Humans; Keratinocytes; p21-Activated Kinases; Precancerous Conditions; Pyrimidine Dimers; Signal Transduction; Skin; Skin Neoplasms; Ultraviolet Rays

2018
Nucleosome positions establish an extended mutation signature in melanoma.
    PLoS genetics, 2018, Volume: 14, Issue:11

    Topics: Chromatin; DNA Repair; DNA, Neoplasm; Female; Genome, Human; Histone Code; Humans; Male; Melanoma; Models, Genetic; Mutation; Neoplasms, Radiation-Induced; Nucleosomes; Prostatic Neoplasms; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2018
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers.
    PLoS genetics, 2018, Volume: 14, Issue:12

    Topics: Base Sequence; Binding Sites; Cell Line, Tumor; DNA Damage; DNA, Neoplasm; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Promoter Regions, Genetic; Proto-Oncogene Proteins c-ets; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Whole Genome Sequencing

2018
Biochemical reconstitution of UV-induced mutational processes.
    Nucleic acids research, 2019, 07-26, Volume: 47, Issue:13

    Topics: 5-Methylcytosine; Cell-Free System; Cytosine; Deamination; DNA Damage; DNA Replication; DNA-Cytosine Methylases; DNA-Directed DNA Polymerase; DNA, Neoplasm; DNA, Single-Stranded; Humans; Melanoma; Models, Genetic; Mutagenesis; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Transcriptome; Ultraviolet Rays

2019
Silver ions enhance UVB-induced phosphorylation of histone H2AX.
    Environmental and molecular mutagenesis, 2014, Volume: 55, Issue:7

    Topics: Anti-Bacterial Agents; Biomarkers; Cell Cycle; Cell Survival; Cell-Free System; DNA Breaks, Double-Stranded; Flow Cytometry; Histones; Humans; Ions; Keratinocytes; Mutagens; Phosphorylation; Pyrimidine Dimers; Pyrimidines; Silver; Skin Neoplasms; Sunlight; Ultraviolet Rays

2014
Sun and ski holidays improve vitamin D status, but are associated with high levels of DNA damage.
    The Journal of investigative dermatology, 2014, Volume: 134, Issue:11

    Topics: Adult; Bathing Beaches; DNA Damage; Female; Holidays; Humans; Male; Middle Aged; Pyrimidine Dimers; Skiing; Skin; Skin Neoplasms; Sunlight; Time Factors; Ultraviolet Rays; Vitamin D; Vitamin D Deficiency

2014
Biomolecules. The dark side of sunlight and melanoma.
    Science (New York, N.Y.), 2015, Feb-20, Volume: 347, Issue:6224

    Topics: Animals; DNA; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms

2015
Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.
    Science (New York, N.Y.), 2015, Feb-20, Volume: 347, Issue:6224

    Topics: Animals; Cells, Cultured; Cytosine; DNA; DNA Damage; Energy Transfer; Humans; Melanins; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Mutagenesis; Mutation; Neoplasms, Radiation-Induced; Photons; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Skin Neoplasms; Sunlight; Thymine; Ultraviolet Rays

2015
Dark CPDs and photocarcinogenesis: the party continues after the lights go out.
    Pigment cell & melanoma research, 2015, Volume: 28, Issue:4

    Topics: Animals; DNA; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms

2015
Autophagy positively regulates DNA damage recognition by nucleotide excision repair.
    Autophagy, 2016, Volume: 12, Issue:2

    Topics: Animals; Autophagy; Carcinogenesis; DNA Damage; DNA Repair; DNA-Binding Proteins; Down-Regulation; E1A-Associated p300 Protein; HEK293 Cells; Humans; Mice; Models, Biological; Nuclear Proteins; Proto-Oncogene Proteins c-akt; Pyrimidine Dimers; Skin Neoplasms; Transcription, Genetic; Twist-Related Protein 1; Ultraviolet Rays

2016
Inhibition of the RhoA GTPase Activity Increases Sensitivity of Melanoma Cells to UV Radiation Effects.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Comet Assay; DNA Damage; DNA Repair; Glutathione Transferase; GTP-Binding Proteins; Humans; Intracellular Signaling Peptides and Proteins; Melanoma; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrimidine Dimers; rhoA GTP-Binding Protein; Skin Neoplasms; Ultraviolet Rays

2016
UV-induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis.
    Toxicologic pathology, 2016, Volume: 44, Issue:4

    Topics: Animals; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Mice; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2016
Concurrent beneficial (vitamin D production) and hazardous (cutaneous DNA damage) impact of repeated low-level summer sunlight exposures.
    The British journal of dermatology, 2016, Volume: 175, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Asia, Southeastern; Biomarkers; Deoxyguanosine; Diet; DNA Damage; DNA Repair; Environmental Exposure; Female; Humans; Male; Middle Aged; Pyrimidine Dimers; Seasons; Skin; Skin Neoplasms; Skin Pigmentation; Sunlight; Vitamin D; Vitamin D Deficiency; Young Adult

2016
Irradiance-dependent UVB Photocarcinogenesis.
    Scientific reports, 2016, 11-21, Volume: 6

    Topics: Adult; Animals; Bromodeoxyuridine; Butadienes; Carcinogenesis; Cell Count; Cell Survival; Cells, Cultured; Dermatitis, Contact; DNA Damage; Extracellular Signal-Regulated MAP Kinases; G2 Phase; Humans; Immunosuppression Therapy; Keratinocytes; Mice, Hairless; Mitosis; Mutation; Nitriles; Protein Kinase Inhibitors; Pyrimidine Dimers; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2016
Inactivation of the vitamin D receptor enhances susceptibility of murine skin to UV-induced tumorigenesis.
    The Journal of investigative dermatology, 2008, Volume: 128, Issue:10

    Topics: Adaptation, Physiological; Animals; Apoptosis; Disease Susceptibility; Epidermis; Keratinocytes; Mice; Mice, Knockout; Neoplasms, Radiation-Induced; Penetrance; Pyrimidine Dimers; Receptors, Calcitriol; Skin; Skin Neoplasms; Ultraviolet Rays; Vitamin D

2008
Repair of UV dimers in skin DNA of patients with basal cell carcinoma.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2008, Volume: 17, Issue:9

    Topics: Adult; Aged; Aged, 80 and over; Buttocks; Carcinoma, Basal Cell; Case-Control Studies; Chromatography, High Pressure Liquid; DNA Damage; DNA Repair; DNA, Neoplasm; Female; Humans; Male; Middle Aged; Pyrimidine Dimers; Risk; Skin; Skin Neoplasms; Sunlight

2008
Differential activity of UV-DDB in mouse keratinocytes and fibroblasts: impact on DNA repair and UV-induced skin cancer.
    DNA repair, 2009, Feb-01, Volume: 8, Issue:2

    Topics: Animals; Disease Susceptibility; DNA Repair; DNA-Binding Proteins; Fibroblasts; Humans; Keratinocytes; Kinetics; Mice; Mice, Hairless; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2009
Photoprotective effect of Pothomorphe umbellata on UVB radiation-induced biomarkers involved in carcinogenesis of hairless mouse epidermis.
    Cutaneous and ocular toxicology, 2009, Volume: 28, Issue:2

    Topics: Administration, Cutaneous; Animals; Apoptosis; Biomarkers; Carcinogenicity Tests; Epidermis; Female; Hyperplasia; Immunohistochemistry; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Piperaceae; Plant Extracts; Proliferating Cell Nuclear Antigen; Pyrimidine Dimers; Radiation-Protective Agents; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2009
Investigation of the effect of UV irradiation on DNA damage: comparison between skin cancer patients and normal volunteers.
    Journal of cutaneous pathology, 2009, Volume: 36, Issue:7

    Topics: Adult; Aged; Carcinoma, Basal Cell; DNA Damage; Dose-Response Relationship, Radiation; Erythema; Female; Humans; Keratinocytes; Male; Middle Aged; Pyrimidine Dimers; Skin Neoplasms; Sunlight; Ultraviolet Rays

2009
Enhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4(R24C/R24C)/Tyr-Nras(Q61K) mice following neonatal UVR.
    Pigment cell & melanoma research, 2010, Volume: 23, Issue:1

    Topics: Administration, Topical; Animals; Animals, Newborn; Antineoplastic Agents; Cell Proliferation; Cyclin-Dependent Kinase 4; Deoxyribonuclease (Pyrimidine Dimer); Disease Models, Animal; DNA Damage; DNA Repair; Keratinocytes; Melanocytes; Melanoma; Mice; Mice, Transgenic; Pyrimidine Dimers; Skin; Skin Neoplasms; Time; Treatment Outcome; Ultraviolet Rays; Up-Regulation; Viral Proteins

2010
DNA repair: How to accurately bypass damage.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Biocatalysis; Crystallography, X-Ray; DNA; DNA Damage; DNA Repair; DNA-Directed DNA Polymerase; Humans; Models, Molecular; Mutation, Missense; Pyrimidine Dimers; Saccharomyces cerevisiae; Skin Neoplasms; Structure-Activity Relationship; Xeroderma Pigmentosum

2010
Structural basis for the suppression of skin cancers by DNA polymerase eta.
    Nature, 2010, Jun-24, Volume: 465, Issue:7301

    Topics: Biocatalysis; Catalytic Domain; Crystallography, X-Ray; DNA; DNA Damage; DNA-Directed DNA Polymerase; Humans; Kinetics; Models, Molecular; Mutation, Missense; Nucleic Acid Conformation; Protein Structure, Tertiary; Pyrimidine Dimers; Saccharomyces cerevisiae; Skin Neoplasms; Structure-Activity Relationship; Xeroderma Pigmentosum

2010
TAT-mediated delivery of a DNA repair enzyme to skin cells rapidly initiates repair of UV-induced DNA damage.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:3

    Topics: Administration, Topical; Cell Line; Cell Nucleus; Chlorella; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Fibroblasts; Humans; Keratinocytes; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Different types of DNA damage play different roles in the etiology of sunlight-induced melanoma.
    Pigment cell & melanoma research, 2011, Volume: 24, Issue:1

    Topics: Animals; Cyprinodontiformes; Disease Models, Animal; DNA Damage; Humans; Melanoma; Models, Biological; Mutation; Pyrimidine Dimers; Reactive Oxygen Species; Skin Neoplasms; Sunlight; Ultraviolet Rays

2011
Is UV-induced mutation formation in melanocytes different from other skin cells?
    Pigment cell & melanoma research, 2011, Volume: 24, Issue:1

    Topics: Animals; DNA Damage; DNA Repair; Fibroblasts; Humans; Keratinocytes; Melanocytes; Melanoma; Mutagenesis; Mutation; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2011
UVB-induced DNA damage, generation of reactive oxygen species, and inflammation are effectively attenuated by the flavonoid luteolin in vitro and in vivo.
    Free radical biology & medicine, 2011, May-01, Volume: 50, Issue:9

    Topics: Acetylcysteine; Antioxidants; Cell Line; Chromans; Cyclooxygenase 2; Cytoprotection; Dinoprostone; DNA Damage; Erythema; Extracellular Signal-Regulated MAP Kinases; Fluoresceins; Gene Expression; Humans; Inflammation; Inhibitory Concentration 50; Keratinocytes; Luteolin; Organ Culture Techniques; Oxidative Stress; p38 Mitogen-Activated Protein Kinases; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Individual photosensitivity of human skin and UVA-induced pyrimidine dimers in DNA.
    The Journal of investigative dermatology, 2011, Volume: 131, Issue:7

    Topics: Adult; Erythema; Humans; Male; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Radiation Tolerance; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Imiquimod-induced TLR7 signaling enhances repair of DNA damage induced by ultraviolet light in bone marrow-derived cells.
    Journal of immunology (Baltimore, Md. : 1950), 2011, Aug-15, Volume: 187, Issue:4

    Topics: Aminoquinolines; Animals; Antineoplastic Agents; Bone Marrow Cells; Cell Line; DNA Damage; DNA Repair; Female; Gene Expression Regulation, Neoplastic; Imiquimod; Membrane Glycoproteins; Mice; Mice, Knockout; Myeloid Differentiation Factor 88; Pyrimidine Dimers; Signal Transduction; Skin Neoplasms; Toll-Like Receptor 7; Ultraviolet Rays; Xeroderma Pigmentosum Group A Protein

2011
Chemopreventive effects of Calluna vulgaris and Vitis vinifera extracts on UVB-induced skin damage in SKH-1 hairless mice.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2011, Volume: 62, Issue:3

    Topics: Animals; Apoptosis; Biphenyl Compounds; Calluna; Cytokines; Disease Models, Animal; Female; Free Radical Scavengers; Humans; Mice; Mice, Hairless; Phytotherapy; Picrates; Plant Extracts; Pyrimidine Dimers; Random Allocation; Seeds; Skin; Skin Neoplasms; Sunburn; Ultraviolet Rays; Vitis

2011
UVA1 induces cyclobutane pyrimidine dimers but not 6-4 photoproducts in human skin in vivo.
    The Journal of investigative dermatology, 2012, Volume: 132, Issue:2

    Topics: DNA Repair; Dose-Response Relationship, Radiation; Erythema; Humans; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2012
Silibinin prevents ultraviolet B radiation-induced epidermal damages in JB6 cells and mouse skin in a p53-GADD45α-dependent manner.
    Carcinogenesis, 2012, Volume: 33, Issue:3

    Topics: Animals; Apoptosis; Cell Cycle; Cell Cycle Proteins; Cell Line, Tumor; Mice; Mice, Hairless; Nuclear Proteins; Pyrimidine Dimers; RNA Interference; RNA, Small Interfering; S Phase Cell Cycle Checkpoints; Silybin; Silymarin; Skin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2012
HPV 5 and 8 E6 abrogate ATR activity resulting in increased persistence of UVB induced DNA damage.
    PLoS pathogens, 2012, Volume: 8, Issue:7

    Topics: Ataxia Telangiectasia Mutated Proteins; Betapapillomavirus; Cell Cycle Checkpoints; Cell Cycle Proteins; Cell Line, Tumor; Cells, Cultured; DNA Breaks, Double-Stranded; Humans; Oncogene Proteins, Viral; p300-CBP Transcription Factors; Protein Serine-Threonine Kinases; Pyrimidine Dimers; RNA Interference; RNA, Messenger; RNA, Small Interfering; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2012
Quantification of ultraviolet radiation-induced DNA damage in the urine of Swedish adults and children following exposure to sunlight.
    Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals, 2012, Volume: 17, Issue:7

    Topics: Adult; Biomarkers; Child; Child, Preschool; DNA Damage; Environmental Exposure; Female; Humans; Male; Middle Aged; Pyrimidine Dimers; Risk Factors; Skin Neoplasms; Statistics, Nonparametric; Sunbathing; Sunlight; Sweden; Ultraviolet Rays; Young Adult

2012
Saponins from Tribulus terrestris L. protect human keratinocytes from UVB-induced damage.
    Journal of photochemistry and photobiology. B, Biology, 2012, Dec-05, Volume: 117

    Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Survival; Disease Progression; DNA Repair; Epidermal Cells; Gene Expression Regulation; Humans; Keratinocytes; NF-kappa B; Pyrimidine Dimers; Saponins; Signal Transduction; Skin Neoplasms; Tribulus; Ultraviolet Rays

2012
UVA1 is skin deep: molecular and clinical implications.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2013, Volume: 12, Issue:1

    Topics: Animals; DNA Damage; Erythema; Humans; Mice; Mutation; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Skin Neoplasms; Ultraviolet Rays

2013
Relationship between skin color and skin response to ultraviolet light.
    International journal of dermatology, 2012, Volume: 51 Suppl 1

    Topics: Black People; Dose-Response Relationship, Radiation; Humans; Melanins; Pyrimidine Dimers; Radiation Dosage; Radiation Injuries; Skin; Skin Neoplasms; Skin Pigmentation; Ultraviolet Rays

2012
Urinary levels of thymine dimer as a biomarker of exposure to ultraviolet radiation in humans during outdoor activities in the summer.
    Mutagenesis, 2013, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Biomarkers; Environmental Exposure; Female; Humans; Male; Middle Aged; Pyrimidine Dimers; Radiation Dosage; Seasons; Skin Neoplasms; Sunlight; Time Factors; Ultraviolet Rays; Young Adult

2013
Nicotinamide enhances repair of ultraviolet radiation-induced DNA damage in human keratinocytes and ex vivo skin.
    Carcinogenesis, 2013, Volume: 34, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Cell Line; Deoxyguanosine; DNA; DNA Damage; DNA Glycosylases; DNA Repair; Humans; Keratinocytes; Niacinamide; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2013
Inhibition of ultraviolet light-induced oxidative events in the skin and internal organs of hairless mice by isoflavone genistein.
    Cancer letters, 2002, Nov-08, Volume: 185, Issue:1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Anticarcinogenic Agents; Brain; Cattle; Deoxyguanosine; DNA Damage; Female; Genistein; Hydrogen Peroxide; In Vitro Techniques; Kidney; Liver; Malondialdehyde; Mice; Mice, Hairless; Oxidation-Reduction; Oxidative Stress; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2002
Similar UV responses are seen in a skin organ culture as in human skin in vivo.
    Experimental dermatology, 2002, Volume: 11, Issue:4

    Topics: Adult; Aged; Aged, 80 and over; DNA Damage; DNA Repair; Female; Humans; Kinetics; Male; Middle Aged; Models, Biological; Neoplasms, Radiation-Induced; Organ Culture Techniques; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunscreening Agents; Tumor Suppressor Protein p53; Ultraviolet Rays

2002
Inhibitory effects of sodium salicylate and acetylsalicylic acid on UVB-induced mouse skin carcinogenesis.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2002, Volume: 11, Issue:12

    Topics: Administration, Topical; Animals; Anticarcinogenic Agents; Aspirin; Biopsy, Needle; Cell Transformation, Neoplastic; Cells, Cultured; Disease Models, Animal; Dose-Response Relationship, Drug; Female; Immunohistochemistry; Mice; Mice, Hairless; Neoplasms, Experimental; Pyrimidine Dimers; Random Allocation; Reference Values; Sensitivity and Specificity; Skin Neoplasms; Sodium Salicylate; Ultraviolet Rays

2002
Efficient repair of cyclobutane pyrimidine dimers at mutational hot spots is restored in complemented Xeroderma pigmentosum group C and trichothiodystrophy/xeroderma pigmentosum group D cells.
    Journal of molecular biology, 2003, Sep-12, Volume: 332, Issue:2

    Topics: Cell Line; Databases, Nucleic Acid; DNA Damage; DNA Repair; DNA, Complementary; Exons; Fibroblasts; Genes, p53; Genetic Therapy; Hair Diseases; Humans; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

2003
Recognition and repair of the cyclobutane thymine dimer, a major cause of skin cancers, by the human excision nuclease.
    Genes & development, 2003, Oct-15, Volume: 17, Issue:20

    Topics: Deoxyribodipyrimidine Photo-Lyase; DNA Ligases; DNA Repair; Humans; Models, Molecular; Protein Structure, Tertiary; Pyrimidine Dimers; Skin Neoplasms

2003
Topical DNA oligonucleotide therapy reduces UV-induced mutations and photocarcinogenesis in hairless mice.
    Proceedings of the National Academy of Sciences of the United States of America, 2004, Mar-16, Volume: 101, Issue:11

    Topics: Administration, Topical; Animals; Antimutagenic Agents; DNA Repair; Mice; Mice, Hairless; Mutation; Neoplasms; Oligodeoxyribonucleotides; Pyrimidine Dimers; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays; Up-Regulation

2004
Silibinin prevents ultraviolet radiation-caused skin damages in SKH-1 hairless mice via a decrease in thymine dimer positive cells and an up-regulation of p53-p21/Cip1 in epidermis.
    Carcinogenesis, 2004, Volume: 25, Issue:8

    Topics: Animals; Anticarcinogenic Agents; Apoptosis; Cell Division; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dimerization; DNA Damage; Epidermis; Female; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Hairless; Models, Biological; Proliferating Cell Nuclear Antigen; Pyrimidine Dimers; Silybin; Silymarin; Skin; Skin Neoplasms; Time Factors; Tumor Suppressor Protein p53; Ultraviolet Rays; Up-Regulation

2004
DNA mismatch repair proteins promote apoptosis and suppress tumorigenesis in response to UVB irradiation: an in vivo study.
    Carcinogenesis, 2004, Volume: 25, Issue:10

    Topics: Animals; Apoptosis; Carcinoma, Squamous Cell; DNA Adducts; DNA Repair; DNA-Binding Proteins; Epidermal Cells; Epidermis; Humans; Mice; Mice, Knockout; Microsatellite Repeats; MutS Homolog 2 Protein; Neoplasm Invasiveness; Neoplasms, Radiation-Induced; Proto-Oncogene Proteins; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2004
XPA gene-deficient, SCF-transgenic mice with epidermal melanin are resistant to UV-induced carcinogenesis.
    The Journal of investigative dermatology, 2004, Volume: 123, Issue:1

    Topics: 9,10-Dimethyl-1,2-benzanthracene; Animals; Carcinogens; Dermatitis; DNA Damage; DNA-Binding Proteins; Epidermis; Immunity, Innate; In Situ Nick-End Labeling; Langerhans Cells; Melanins; Melanocytes; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Transgenic; Pyrimidine Dimers; Skin Neoplasms; Stem Cell Factor; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2004
Skin cancer: lights on genome lesions.
    Current biology : CB, 2005, Jan-26, Volume: 15, Issue:2

    Topics: Animals; DNA Damage; DNA Repair Enzymes; Mice; Mice, Transgenic; Models, Biological; Mutagenesis; Pyrimidine Dimers; Skin Neoplasms; Sunlight; Ultraviolet Rays

2005
Powerful skin cancer protection by a CPD-photolyase transgene.
    Current biology : CB, 2005, Jan-26, Volume: 15, Issue:2

    Topics: Animals; Apoptosis; Carcinoma; Cell Line; Deoxyribodipyrimidine Photo-Lyase; DNA Damage; DNA Repair; Gene Expression; Mice; Mice, Transgenic; Pyrimidine Dimers; Reverse Transcriptase Polymerase Chain Reaction; Skin Neoplasms; Ultraviolet Rays

2005
Dietary feeding of silibinin prevents early biomarkers of UVB radiation-induced carcinogenesis in SKH-1 hairless mouse epidermis.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2005, Volume: 14, Issue:5

    Topics: Animals; Apoptosis; Cell Proliferation; Chemoprevention; Dietary Supplements; DNA Damage; DNA Repair; Epidermis; Immunohistochemistry; In Situ Nick-End Labeling; Mice; Mice, Hairless; Models, Animal; Pyrimidine Dimers; Silybin; Silymarin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2005
The photocarcinogenesis of antibiotic lomefloxacin and UVA radiation is enhanced in xeroderma pigmentosum group A gene-deficient mice.
    The Journal of investigative dermatology, 2005, Volume: 125, Issue:3

    Topics: Animals; Anti-Bacterial Agents; Carcinogens; DNA Damage; DNA-Binding Proteins; Fluoroquinolones; Mice; Mice, Mutant Strains; Mutation; Neoplasms, Radiation-Induced; Photosensitizing Agents; Pyrimidine Dimers; Quinolones; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum Group A Protein

2005
Enhanced DDB2 expression protects mice from carcinogenic effects of chronic UV-B irradiation.
    Cancer research, 2005, Nov-15, Volume: 65, Issue:22

    Topics: Animals; Apoptosis; DNA Repair; DNA-Binding Proteins; Female; Fibroblasts; Male; Mice; Mice, Hairless; Mice, Transgenic; Oligopeptides; Peptides; Pyrimidine Dimers; Radiation Tolerance; Skin; Skin Neoplasms; Ultraviolet Rays

2005
Calcineurin inhibitors decrease DNA repair and apoptosis in human keratinocytes following ultraviolet B irradiation.
    The Journal of investigative dermatology, 2005, Volume: 125, Issue:5

    Topics: Active Transport, Cell Nucleus; Apoptosis; Calcineurin Inhibitors; Cell Nucleus; Cyclosporine; DNA; DNA Damage; DNA Repair; Enzyme Inhibitors; Humans; Keratinocytes; NFATC Transcription Factors; Pyrimidine Dimers; Skin Neoplasms; Tacrolimus; Ultraviolet Rays

2005
ATX-S10(Na)-photodynamic therapy is less carcinogenic for mouse skin compared with ultraviolet B irradiation.
    The British journal of dermatology, 2005, Volume: 153, Issue:6

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Cell Transformation, Neoplastic; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Radiation; Female; Keratinocytes; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Photochemotherapy; Porphyrins; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Therapy

2005
Photoprotective effect of isoflavone genistein on ultraviolet B-induced pyrimidine dimer formation and PCNA expression in human reconstituted skin and its implications in dermatology and prevention of cutaneous carcinogenesis.
    Carcinogenesis, 2006, Volume: 27, Issue:8

    Topics: Anticarcinogenic Agents; Cells, Cultured; Dermatology; Epidermis; Genistein; Humans; Proliferating Cell Nuclear Antigen; Pyrimidine Dimers; Skin; Skin Neoplasms; Skin, Artificial; Ultraviolet Rays

2006
Enhanced photocarcinogenesis in interleukin-12-deficient mice.
    Cancer research, 2006, Mar-15, Volume: 66, Issue:6

    Topics: Animals; Cell Growth Processes; Cocarcinogenesis; Electric Impedance; Genes, p53; Interleukin-10; Interleukin-12; Interleukin-12 Subunit p40; Mice; Mice, Inbred C57BL; Mice, Knockout; Mice, Nude; Neoplasm Invasiveness; Protein Subunits; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunburn; Ultraviolet Rays

2006
Caffeine and caffeine sodium benzoate have a sunscreen effect, enhance UVB-induced apoptosis, and inhibit UVB-induced skin carcinogenesis in SKH-1 mice.
    Carcinogenesis, 2007, Volume: 28, Issue:1

    Topics: Administration, Topical; Animals; Antimutagenic Agents; Apoptosis; Benzoates; Caffeine; Cell Transformation, Neoplastic; Central Nervous System Stimulants; Drug Combinations; Female; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Knockout; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunburn; Sunscreening Agents; Ultraviolet Rays

2007
Revisiting the photochemistry of solar UVA in human skin.
    Proceedings of the National Academy of Sciences of the United States of America, 2006, Sep-12, Volume: 103, Issue:37

    Topics: Environment; Humans; Photochemistry; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2006
Differential role of basal keratinocytes in UV-induced immunosuppression and skin cancer.
    Molecular and cellular biology, 2006, Volume: 26, Issue:22

    Topics: Animals; Apoptosis; Carcinoma; Carnitine; Cluster Analysis; Deoxyribodipyrimidine Photo-Lyase; Hyperplasia; Immunosuppression Therapy; Keratin-14; Keratinocytes; Mice; Mice, Transgenic; Oligonucleotide Array Sequence Analysis; Pyrimidine Dimers; Radiation Tolerance; Skin; Skin Neoplasms; Transcription, Genetic; Ultraviolet Rays

2006
Epidermal stem and progenitor cells in murine epidermis accumulate UV damage despite NER proficiency.
    Carcinogenesis, 2007, Volume: 28, Issue:4

    Topics: Animals; Antigens, Surface; Bromodeoxyuridine; DNA Damage; DNA Repair; DNA-Binding Proteins; Epidermal Cells; Fibroblasts; Humans; Membrane Glycoproteins; Mice; Mice, Hairless; Mice, Knockout; Mice, Transgenic; Photobiology; Pyrimidine Dimers; Radiation Tolerance; Skin Neoplasms; Stem Cells; Tumor Suppressor Protein p53; Ultraviolet Rays

2007
[Harmful effects of solar UVA radiation: new indices in DNA].
    Medecine sciences : M/S, 2007, Volume: 23, Issue:2

    Topics: Adolescent; Adult; Biomarkers; Child; DNA; DNA Damage; Humans; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Sunlight; Sunscreening Agents; Ultraviolet Rays

2007
Effect of ultraviolet (UV) A, UVB or ionizing radiation on the cell cycle of human melanoma cells.
    The British journal of dermatology, 2007, Volume: 156, Issue:5

    Topics: Cell Cycle; DNA Damage; Humans; Melanoma; Pyrimidine Dimers; Radiation, Ionizing; Skin Neoplasms; Ultraviolet Rays

2007
Narrow-band UVB induces more carcinogenic skin tumors than broad-band UVB through the formation of cyclobutane pyrimidine dimer.
    The Journal of investigative dermatology, 2007, Volume: 127, Issue:12

    Topics: Animals; Cell Transformation, Neoplastic; Cyclobutanes; DNA Glycosylases; Epidermis; Guanosine; Humans; Immunohistochemistry; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mice, Knockout; Photochemistry; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2007
Topical thymidine dinucleotide treatment reduces development of ultraviolet-induced basal cell carcinoma in Ptch-1+/- mice.
    The American journal of pathology, 2008, Volume: 172, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Cutaneous; Animals; Anticarcinogenic Agents; Apoptosis; Basal Cell Nevus Syndrome; Carcinoma, Basal Cell; Cell Nucleus; Cell Size; Deoxyguanosine; Humans; Mice; Patched Receptors; Patched-1 Receptor; Pyrimidine Dimers; Receptors, Cell Surface; Skin; Skin Neoplasms; Thymine Nucleotides; Ultraviolet Rays

2008
Ultraviolet light action spectra for neoplastic transformation and lethality of Syrian hamster embryo cells correlate with spectrum for pyrimidine dimer formation in cellular DNA.
    Proceedings of the National Academy of Sciences of the United States of America, 1981, Volume: 78, Issue:4

    Topics: Animals; Cell Survival; Cell Transformation, Neoplastic; Cells, Cultured; Cricetinae; Models, Biological; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Spectrum Analysis; Ultraviolet Rays

1981
Substitution of equally carcinogenic UV-A for UV-B irradiations lowers epidermal thymine dimer levels during skin cancer induction in hairless mice.
    Carcinogenesis, 1995, Volume: 16, Issue:10

    Topics: Animals; Cell Cycle; Dactinomycin; Epidermis; Female; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Time Factors; Ultraviolet Rays

1995
Processing of directly and indirectly ultraviolet-induced DNA damage in human cells.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1995, Volume: 139

    Topics: Cell Line, Transformed; Cell Transformation, Neoplastic; Chloramphenicol O-Acetyltransferase; DNA; DNA Damage; DNA Repair; DNA, Bacterial; DNA, Recombinant; Genetic Vectors; Herpesvirus 4, Human; Humans; Lymphocytes; Methylene Blue; Neoplasms, Radiation-Induced; Oxidative Stress; Oxygen; Plasmids; Pyrimidine Dimers; Radiation-Sensitizing Agents; Recombinant Fusion Proteins; Singlet Oxygen; Skin Neoplasms; Tissue Extracts; Ultraviolet Rays; Xeroderma Pigmentosum

1995
Different removal of ultraviolet photoproducts in genetically related xeroderma pigmentosum and trichothiodystrophy diseases.
    Cancer research, 1995, Oct-01, Volume: 55, Issue:19

    Topics: Cell Line; Chloramphenicol O-Acetyltransferase; DNA Repair; Genes, Reporter; Hair; Humans; Luciferases; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1995
Detection of thymine dimers in suprabasal and basal cells of chronically UV-B exposed hairless mice.
    The Journal of investigative dermatology, 1993, Volume: 100, Issue:6

    Topics: Animals; Dose-Response Relationship, Radiation; Epidermal Cells; Female; Fluorescence; Immunohistochemistry; Mice; Mice, Hairless; Pyrimidine Dimers; Skin; Skin Neoplasms; Staining and Labeling; Time Factors; Ultraviolet Rays

1993
UV induction of cyclobutane thymine dimers in the DNA of cultured melanocytes from foreskin, common melanocytic nevi and dysplastic nevi.
    Photochemistry and photobiology, 1994, Volume: 59, Issue:5

    Topics: Cells, Cultured; DNA; Dysplastic Nevus Syndrome; Humans; Male; Melanocytes; Nevus, Pigmented; Pyrimidine Dimers; Skin Neoplasms; Tumor Cells, Cultured; Ultraviolet Rays

1994
Slow repair of pyrimidine dimers at p53 mutation hotspots in skin cancer.
    Science (New York, N.Y.), 1994, Mar-11, Volume: 263, Issue:5152

    Topics: Cells, Cultured; DNA Repair; Exons; Genes, p53; HeLa Cells; Humans; Mutation; Phosphoglycerate Kinase; Polymerase Chain Reaction; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

1994
The distribution of UV photoproducts along the human p53 gene and its relation to mutations in skin cancer.
    Oncogene, 1993, Volume: 8, Issue:8

    Topics: Base Sequence; Codon; DNA Damage; Exons; Genes, p53; Humans; Male; Molecular Sequence Data; Mutation; Photochemistry; Polymerase Chain Reaction; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1993
8-hydroxy-2'-deoxyguanosine is increased in epidermal cells of hairless mice after chronic ultraviolet B exposure.
    The Journal of investigative dermatology, 1996, Volume: 107, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Animals; Deoxyguanosine; Male; Mice; Mice, Hairless; Pyrimidine Dimers; Skin; Skin Neoplasms; Tyrosine; Ultraviolet Rays

1996
Ultraviolet B radiation-induced DNA lesions in mouse epidermis: an assessment using a novel 32P-postlabelling technique.
    Biochemical and biophysical research communications, 1996, Dec-13, Volume: 229, Issue:2

    Topics: Animals; DNA; Epidermis; Female; Guanosine Triphosphate; Mice; Mice, Hairless; Phosphorus Radioisotopes; Pyrimidine Dimers; Silymarin; Skin Neoplasms; Sunscreening Agents; Ultraviolet Rays

1996
Epidermal proliferation but not quantity of DNA photodamage is correlated with UV-induced mouse skin carcinogenesis.
    The Journal of investigative dermatology, 1997, Volume: 109, Issue:3

    Topics: Animals; Bromodeoxyuridine; Cell Division; DNA; DNA Damage; Female; Gene Expression; Genes, p53; Genetic Predisposition to Disease; Hyperplasia; Mice; Mice, Hairless; Mice, Inbred SENCAR; Neoplasms, Radiation-Induced; Ornithine Decarboxylase; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

1997
Sunlight induces pyrimidine dimers preferentially at 5-methylcytosine bases.
    Cancer research, 1997, Nov-01, Volume: 57, Issue:21

    Topics: 5-Methylcytosine; Codon; Cytosine; Genes, p53; Humans; Keratinocytes; Methylation; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Sunlight

1997
UVB-induced cyclobutane pyrimidine dimer frequency correlates with skin cancer mutational hotspots in p53.
    Photochemistry and photobiology, 1997, Volume: 66, Issue:5

    Topics: Base Sequence; Cells, Cultured; DNA; Genes, p53; Humans; Molecular Sequence Data; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1997
Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation.
    Carcinogenesis, 1997, Volume: 18, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Cells, Cultured; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Melanoma; Oxidation-Reduction; Pyrimidine Dimers; Skin; Skin Neoplasms; Spectrum Analysis; Ultraviolet Rays

1997
Inhibition of cyclobutane pyrimidine dimer formation in epidermal p53 gene of UV-irradiated mice by alpha-tocopherol.
    Nutrition and cancer, 1997, Volume: 29, Issue:3

    Topics: Administration, Cutaneous; Animals; Blotting, Southern; Female; Genes, p53; Mice; Mice, Inbred BALB C; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Specific Pathogen-Free Organisms; Time Factors; Ultraviolet Rays; Vitamin E

1997
High levels of dipyrimidine dimers are induced in human skin by solar-simulating UV radiation.
    Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 1998, Volume: 7, Issue:3

    Topics: Adolescent; Adult; DNA Adducts; DNA Repair; Dose-Response Relationship, Radiation; Female; Humans; Male; Middle Aged; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Risk Factors; Skin; Skin Neoplasms; Sunlight; Ultraviolet Rays

1998
Sunlight and carcinogenesis: expression of p53 and pyrimidine dimers in human skin following UVA I, UVA I + II and solar simulating radiations.
    International journal of cancer, 1998, Apr-13, Volume: 76, Issue:2

    Topics: Adult; Antibodies; DNA; DNA Damage; Gene Expression; Genes, p53; Humans; Immunohistochemistry; Middle Aged; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunlight; Tumor Suppressor Protein p53; Ultraviolet Rays

1998
Defective global genome repair in XPC mice is associated with skin cancer susceptibility but not with sensitivity to UVB induced erythema and edema.
    The Journal of investigative dermatology, 1998, Volume: 110, Issue:4

    Topics: Animals; Carcinoma, Squamous Cell; DNA Repair; Dose-Response Relationship, Radiation; Edema; Erythema; Genetic Predisposition to Disease; Genome; Mice; Mice, Knockout; Photosensitivity Disorders; Pyrimidine Dimers; Radiation Injuries, Experimental; Skin Neoplasms; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1998
Sensitive 32P-HPLC technique shows base sequence dependent differences in photolesion repair in human keratinocytes.
    Chemico-biological interactions, 1998, Mar-12, Volume: 110, Issue:1-2

    Topics: Cells, Cultured; Chromatography, High Pressure Liquid; DNA Adducts; DNA Damage; DNA Repair; Erythema; Humans; Keratinocytes; Phosphorus Radioisotopes; Phosphorylation; Photochemistry; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1998
In situ molecular dosimetry and tumor risk: UV-induced DNA damage and tumor latency time.
    Photochemistry and photobiology, 1998, Volume: 68, Issue:4

    Topics: Animals; Cell Transformation, Neoplastic; Cells, Cultured; DNA; DNA Damage; Epidermis; Female; Hyperplasia; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Time Factors; Ultraviolet Rays

1998
Sequence and time-dependent deamination of cytosine bases in UVB-induced cyclobutane pyrimidine dimers in vivo.
    Journal of molecular biology, 1998, Nov-27, Volume: 284, Issue:2

    Topics: Carbon-Oxygen Lyases; Cytosine; Deamination; Deoxyribodipyrimidine Photo-Lyase; Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA-(Apurinic or Apyrimidinic Site) Lyase; Fibroblasts; Genes, jun; Genes, p53; Humans; Mutagenesis; Pyrimidine Dimers; Skin Neoplasms; Time Factors; Ultraviolet Rays

1998
The multilayered organization of engineered human skin does not influence the formation of sunlight-induced cyclobutane pyrimidine dimers in cellular DNA.
    Cancer research, 1999, Jan-15, Volume: 59, Issue:2

    Topics: Biomedical Engineering; DNA; Humans; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunlight

1999
Spectrum of p53 gene mutations suggests a possible role for ultraviolet radiation in the pathogenesis of advanced cutaneous lymphomas.
    The Journal of investigative dermatology, 1999, Volume: 112, Issue:3

    Topics: Female; Genes, p53; Humans; Lymphoma; Male; Mutation; Polymerase Chain Reaction; Polymorphism, Single-Stranded Conformational; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1999
Prevention of DNA photodamage by vitamin E compounds and sunscreens: roles of ultraviolet absorbance and cellular uptake.
    Molecular carcinogenesis, 1999, Volume: 24, Issue:3

    Topics: Administration, Cutaneous; alpha-Tocopherol; Animals; Anticarcinogenic Agents; Benzophenones; Biological Transport; Cell Nucleus; Cells, Cultured; Cinnamates; DNA Damage; Ethers; Female; Keratinocytes; Mice; Mice, Inbred C3H; Neoplasms, Radiation-Induced; Photochemistry; Pyrimidine Dimers; Radiation Tolerance; Radiation-Protective Agents; Salicylates; Skin; Skin Neoplasms; Sunscreening Agents; Tocopherols; Ultraviolet Rays; Vitamin E

1999
hRAD30 mutations in the variant form of xeroderma pigmentosum.
    Science (New York, N.Y.), 1999, Jul-09, Volume: 285, Issue:5425

    Topics: Alleles; Amino Acid Sequence; Cell Line; DNA Damage; DNA Polymerase iota; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; DNA, Complementary; Frameshift Mutation; Humans; Molecular Sequence Data; Mutation; Neoplasms, Radiation-Induced; Protein Biosynthesis; Pyrimidine Dimers; Saccharomyces cerevisiae; Sequence Alignment; Sequence Deletion; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1999
Involvement of 5-methylcytosine in sunlight-induced mutagenesis.
    Journal of molecular biology, 1999, Oct-29, Volume: 293, Issue:3

    Topics: 5-Methylcytosine; Animals; Bacterial Proteins; Base Sequence; Cells, Cultured; CpG Islands; Cytosine; DNA Methylation; DNA Mutational Analysis; Escherichia coli Proteins; Fibroblasts; Genes, p53; Humans; Lac Repressors; Mice; Mice, Transgenic; Models, Genetic; Molecular Sequence Data; Mutagenesis; Mutation; Pyrimidine Dimers; Repressor Proteins; Skin Neoplasms; Sunlight; Transgenes; Ultraviolet Rays

1999
Cutaneous melanoma patients have normal repair kinetics of ultraviolet-induced DNA repair in skin in situ.
    The Journal of investigative dermatology, 2000, Volume: 114, Issue:4

    Topics: Adult; DNA Repair; Female; Humans; Male; Melanoma; Middle Aged; Pyrimidine Dimers; Skin; Skin Neoplasms; Time Factors; Ultraviolet Rays

2000
A molecular pathway for UV-induced CC to TT mutations.
    Mutation research, 2000, Feb-14, Volume: 447, Issue:2

    Topics: DNA Repair; Genes, p53; Humans; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

2000
Preventive effect of antioxidant on ultraviolet-induced skin cancer in mice.
    Journal of dermatological science, 2000, Volume: 23 Suppl 1

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Topical; Animals; Antioxidants; Deoxyguanosine; Female; Humans; Mice; Neoplasms, Radiation-Induced; Olive Oil; Plant Oils; Pyrimidine Dimers; Reactive Oxygen Species; Skin Neoplasms; Ultraviolet Rays

2000
CC to TT mutation in the mitochondrial DNA of normal skin: relationship to ultraviolet light exposure.
    Mutation research, 2000, Jun-22, Volume: 468, Issue:1

    Topics: Aged; Aged, 80 and over; Alleles; DNA, Mitochondrial; Dose-Response Relationship, Radiation; Female; Humans; Male; Middle Aged; Mutation; Polymerase Chain Reaction; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2000
Levels and repair of cyclobutane pyrimidine dimers and 6-4 photoproducts in skin of sporadic basal cell carcinoma patients.
    The Journal of investigative dermatology, 2000, Volume: 115, Issue:1

    Topics: Aged; Carcinoma, Basal Cell; Deoxyribodipyrimidine Photo-Lyase; DNA Repair; Erythema; Humans; Middle Aged; Pyrimidine Dimers; Skin Neoplasms

2000
Induction, distribution and repair of UV photodamage in the platyfish, Xiphophorus signum.
    Photochemistry and photobiology, 2000, Volume: 72, Issue:2

    Topics: Animals; Cyprinodontiformes; DNA Repair; Melanoma; Neoplasms, Radiation-Induced; Photobiology; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2000
The spectrum of mitochondrial DNA deletions is a ubiquitous marker of ultraviolet radiation exposure in human skin.
    The Journal of investigative dermatology, 2000, Volume: 115, Issue:4

    Topics: Biomarkers; DNA, Mitochondrial; Gene Deletion; Genetic Complementation Test; Humans; Mutation; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

2000
Immunochemical quantitation of UV-induced oxidative and dimeric DNA damage to human keratinocytes.
    Free radical research, 2000, Volume: 33, Issue:4

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Cell Line, Transformed; Deoxyguanosine; DNA Damage; Humans; Hydrogen Peroxide; Immunohistochemistry; Keratinocytes; Nucleic Acid Denaturation; Oxidation-Reduction; Pyrimidine Dimers; Simian virus 40; Skin Neoplasms; Ultraviolet Rays

2000
Protective effect of topically applied olive oil against photocarcinogenesis following UVB exposure of mice.
    Carcinogenesis, 2000, Volume: 21, Issue:11

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Topical; Animals; Anticarcinogenic Agents; Deoxyguanosine; Female; Mice; Mice, Hairless; Mice, Inbred BALB C; Olive Oil; Plant Oils; Pyrimidine Dimers; Skin; Skin Neoplasms; Tumor Suppressor Protein p53; Ultraviolet Rays

2000
Cyclobutane pyrimidine dimers form preferentially at the major p53 mutational hotspot in UVB-induced mouse skin tumors.
    Carcinogenesis, 2000, Volume: 21, Issue:11

    Topics: Animals; Codon; CpG Islands; DNA Methylation; DNA Repair; Epidermis; Female; Genes, p53; Mice; Mice, Hairless; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2000
The dose dependence of cyclobutane dimer induction and repair in UVB-irradiated human keratinocytes.
    Photochemistry and photobiology, 2000, Volume: 72, Issue:5

    Topics: Cell Line; Dose-Response Relationship, Radiation; Humans; Keratinocytes; Neoplasms, Radiation-Induced; Photobiology; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2000
Protective effects of sunscreening agents on photocarcinogenesis, photoaging, and DNA damage in XPA gene knockout mice.
    Archives of dermatological research, 2000, Volume: 292, Issue:10

    Topics: Aging; Animals; Disease Models, Animal; DNA-Binding Proteins; Ear; Fluorescent Antibody Technique; Mast Cells; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Mice, Knockout; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunscreening Agents; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group A Protein

2000
Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis.
    Journal of molecular biology, 2001, Jan-19, Volume: 305, Issue:3

    Topics: 5-Methylcytosine; Animals; Bacterial Proteins; Base Sequence; Cell Line; CpG Islands; Cytosine; DNA Methylation; Escherichia coli Proteins; Fibroblasts; Genes, p53; Humans; Lac Operon; Lac Repressors; Mice; Models, Genetic; Molecular Sequence Data; Mutagenesis; Pyrimidine Dimers; Repressor Proteins; Skin Neoplasms; Sunlight; Transcription Factors; Transgenes; Ultraviolet Rays; Viral Proteins

2001
Attenuation of DNA damage in the dermis and epidermis of the albino hairless mouse by chronic exposure to ultraviolet-A and -B radiation.
    Photochemistry and photobiology, 2001, Volume: 73, Issue:1

    Topics: Animals; DNA Damage; Dose-Response Relationship, Radiation; Female; Mice; Mice, Hairless; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2001
Immunoexpression of ultraviolet photoproducts and p53 mutation analysis in atypical fibroxanthoma and superficial malignant fibrous histiocytoma.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2001, Volume: 14, Issue:6

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Base Sequence; DNA; DNA Mutational Analysis; Female; Histiocytoma, Benign Fibrous; Humans; Immunohistochemistry; Male; Middle Aged; Mutation; Polymorphism, Single-Stranded Conformational; Pyrimidine Dimers; Skin Neoplasms; Tumor Suppressor Protein p53

2001
Repeated exposures of human skin equivalent to low doses of ultraviolet-B radiation lead to changes in cellular functions and accumulation of cyclobutane pyrimidine dimers.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 2001, Volume: 79, Issue:4

    Topics: Adult; Cell Division; Humans; In Vitro Techniques; Microscopy, Electron; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Radioimmunoassay; Skin; Skin Neoplasms; Ultraviolet Rays

2001
UV-induced DNA damage and mutations in Hupki (human p53 knock-in) mice recapitulate p53 hotspot alterations in sun-exposed human skin.
    Cancer research, 2001, Nov-15, Volume: 61, Issue:22

    Topics: Amino Acid Sequence; Animals; Chromosome Mapping; DNA Damage; Genes, p53; Humans; Mice; Molecular Sequence Data; Mutation; Protein Structure, Tertiary; Pyrimidine Dimers; Recombinant Fusion Proteins; Skin; Skin Neoplasms; Sunlight; Ultraviolet Rays

2001
Ultraviolet photoproduct levels in melanocytic nevi and surrounding epidermis in human skin in situ.
    The Journal of investigative dermatology, 2002, Volume: 118, Issue:1

    Topics: Adult; Color; Female; Humans; Male; Middle Aged; Nevus, Pigmented; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2002
In situ repair of cyclobutane pyrimidine dimers in skin and melanocytic nevi of cutaneous melanoma patients.
    International journal of cancer, 2002, Mar-20, Volume: 98, Issue:3

    Topics: Adult; Biopsy; Chromatography, High Pressure Liquid; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Middle Aged; Nevus, Pigmented; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2002
Pyrimidine dimer excision in human cells and skin cancer.
    National Cancer Institute monograph, 1978, Issue:50

    Topics: Animals; Cell Line; Cricetinae; DNA Repair; DNA, Neoplasm; Fibroblasts; Humans; Mice; Neoplasms, Experimental; Pyrimidine Dimers; Skin Neoplasms; Time Factors; Ultraviolet Rays; Xeroderma Pigmentosum

1978
Formation of thymine containing dimers in skin exposed to ultraviolet radiation.
    Bulletin du cancer, 1978, Volume: 65, Issue:3

    Topics: Animals; DNA; DNA Repair; DNA Replication; Guinea Pigs; Mice; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Time Factors; Ultraviolet Rays

1978
Immunochemical detection of unrepaired cyclobutane-type pyrimidine dimers of DNAs extracted from human skin tumours.
    Archives of dermatological research, 1992, Volume: 284, Issue:5

    Topics: Adult; Animals; DNA; DNA Damage; DNA Repair; Fluorescent Antibody Technique; Humans; Immune Sera; Immunoblotting; Leukocytes; Pyrimidine Dimers; Rabbits; Skin Neoplasms; Ultraviolet Rays

1992
Pyrimidine dimer removal enhanced by DNA repair liposomes reduces the incidence of UV skin cancer in mice.
    Cancer research, 1992, Aug-01, Volume: 52, Issue:15

    Topics: Animals; Deoxyribonuclease (Pyrimidine Dimer); DNA Damage; DNA Repair; Drug Carriers; Endodeoxyribonucleases; Female; Humans; Liposomes; Mice; Mice, Hairless; Neoplasms, Radiation-Induced; Organ Culture Techniques; Pyrimidine Dimers; Skin; Skin Neoplasms; T-Phages; Tissue Distribution; Ultraviolet Rays; Viral Proteins

1992
Photoreactivation of ultraviolet radiation-induced skin and eye tumors of Monodelphis domestica.
    Cancer research, 1991, Dec-15, Volume: 51, Issue:24

    Topics: Animals; Cornea; Deoxyribodipyrimidine Photo-Lyase; DNA Repair; Eye Neoplasms; Neoplasms, Radiation-Induced; Opossums; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

1991
UV-mediated interaction of psoralens with the genome.
    Current problems in dermatology, 1986, Volume: 15

    Topics: Animals; Chemical Phenomena; Chemistry; Cross-Linking Reagents; DNA; DNA Repair; Escherichia coli; Eukaryotic Cells; Furocoumarins; Humans; Neoplasms, Radiation-Induced; Nucleic Acid Conformation; Oxygen; PUVA Therapy; Pyrimidine Dimers; Pyrimidines; RNA; Skin Neoplasms; Ultraviolet Rays

1986
Establishment and characterization of a melanoma cell line from a xeroderma pigmentosum patient: activation of N-ras at a potential pyrimidine dimer site.
    Cancer research, 1989, Mar-01, Volume: 49, Issue:5

    Topics: Animals; Child; Chromosome Aberrations; DNA Repair; Genes, ras; Humans; Melanoma; Mice; Mutation; Phenotype; Pyrimidine Dimers; Skin Neoplasms; Tumor Cells, Cultured; Ultraviolet Rays; Xeroderma Pigmentosum

1989
Distribution of thymine dimers induced in mouse skin by ultraviolet radiation.
    Photo-dermatology, 1988, Volume: 5, Issue:1

    Topics: Animals; Antibodies, Monoclonal; DNA Damage; Female; Fluorescent Antibody Technique; Mice; Mice, Inbred BALB C; Mice, Inbred C3H; Pyrimidine Dimers; Skin; Skin Neoplasms; Species Specificity; Ultraviolet Rays

1988
Immunochemical determination of an initial step in thymine dimer excision repair in xeroderma pigmentosum variant fibroblasts and biopsy material from the normal population and patients with basal cell carcinoma and melanoma.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Adult; Antibodies, Monoclonal; Carcinoma, Basal Cell; DNA; DNA Repair; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Male; Melanoma; Middle Aged; Mutation; Pyrimidine Dimers; Skin Neoplasms; Xeroderma Pigmentosum

1987
The (6-4) photoproduct and human skin cancer.
    Photo-dermatology, 1988, Volume: 5, Issue:2

    Topics: DNA; DNA Repair; Humans; Pyrimidine Dimers; Skin Neoplasms; Sunlight

1988
Photocarcinogenesis and persistent hyperplasia in UV-irradiated SENCAR mouse skin.
    Environmental health perspectives, 1986, Volume: 68

    Topics: Animals; Cell Division; Hyperplasia; Mice; Mice, Inbred Strains; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Neoplasms; Species Specificity; Ultraviolet Rays

1986
Molecular targets of UVB.
    Current problems in dermatology, 1986, Volume: 15

    Topics: Cell Division; Cells, Cultured; Colony-Forming Units Assay; DNA; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Interphase; Lymphocytes; Melanocytes; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Sister Chromatid Exchange; Skin; Skin Neoplasms; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Ultraviolet radiation-induced histopathological changes in the skin of the marsupial Monodelphis domestica. I. The effects of acute and chronic exposures and of photoreactivation treatment.
    The British journal of dermatology, 1985, Volume: 113, Issue:2

    Topics: Animals; DNA Repair; Light; Neoplasms, Radiation-Induced; Opossums; Precancerous Conditions; Pyrimidine Dimers; Radiation Dosage; Skin; Skin Neoplasms; Time Factors; Ultraviolet Rays

1985