Page last updated: 2024-08-26

pyrimidine dimers and Malignant Melanoma

pyrimidine dimers has been researched along with Malignant Melanoma in 46 studies

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-19904 (8.70)18.7374
1990's3 (6.52)18.2507
2000's9 (19.57)29.6817
2010's25 (54.35)24.3611
2020's5 (10.87)2.80

Authors

AuthorsStudies
Albrecht, AV; Bohm, KA; Emehiser, RG; Hrdlicka, PJ; Mao, P; Poon, GMK; Roberts, SA; Sivapragasam, S; Stark, B; Wyrick, JJ1
Poon, GMK; Selvam, K; Sivapragasam, S; Wyrick, JJ1
Boström, M; Elliott, K; Larsson, E; Lindberg, M1
Brash, DE; Han, L; Knight, J; Kornacker, K; Mehta, S; Palmatier, MA; Premi, S; Zhao, D1
Frigola, J; Gonzalez-Perez, A; Lopez-Bigas, N; Sabarinathan, R1
Emri, G; Fidrus, E; Hegedűs, C; Janka, EA; Paragh, G; Remenyik, É1
Jin, SG; Johnson, J; Li, P; Pettinga, D; Pfeifer, GP1
Duoji, G; Grigalavicius, M; Jie, D; Juzeniene, A; Pudroma, X1
Bellnier, D; Fidrus, E; Mudambi, S; Paragh, G; Pera, P; Remenyik, E; Shafirstein, G; Washington, D1
Brown, AJ; Esaki, S; Lockwood, S; Mao, P; Poon, GMK; Roberts, SA; Smerdon, MJ; Wyrick, JJ1
Brown, AJ; Mao, P; Roberts, SA; Smerdon, MJ; Wyrick, JJ1
Boström, M; Clausen, AR; Elliott, K; Filges, S; Larsson, E; Lindberg, M; Ståhlberg, A; Van den Eynden, J1
Bíró, T; Boros, IM; Borsos, BN; Buzas, K; Coin, F; Hudacsek, VV; Kovács, I; Majoros, H; Nagy, Z; Pankotai, T; Ujfaludi, Z1
Chen, Y; Sugiyama, T1
Boyce, Z; Hacker, E; Hayward, NK; Kimlin, MG; Pollak, T; Vaartjes, SA; Whiteman, DC; Wockner, L1
Taylor, JS1
Bacchiocchi, A; Bechara, EJ; Brash, DE; Douki, T; Halaban, R; Mano, CM; Premi, S; Wakamatsu, K; Wallisch, S; Weiner, AB1
Abdel-Malek, ZA; Cassidy, P1
Carson, C; Chastain, PD; Cordeiro-Stone, M; Gibbs-Flournoy, E; Ibrahim, JG; Kaufmann, WK; McNulty, JJ; Mitchell, DL; Rao, S; Simpson, DA; Sproul, CD; Thomas, NE; Zhou, Y1
Costa, ET; Espinha, G; Forti, FL; Osaki, JH1
Amar, SK; Chaturvedi, RK; Dwivedi, A; Goyal, S; Kushwaha, HN; Mujtaba, SF; Ray, RS; Srivastav, AK; Verma, A1
Brash, DE1
Blasiak, J; Pawlowska, E; Wysokinski, D1
Brash, DE; Premi, S1
D'Orazio, JA; Jarrett, SG1
Mukhopadhyay, P; Roberts, JA; Walker, GJ1
Fahey, P; Hacker, E; Hayward, N; Muller, HK; Walker, G1
Fernandez, AA; Mitchell, DL1
Rünger, TM1
Besaratinia, A; Pfeifer, GP1
Besaratinia, A; Pfeifer, GP; You, YH1
Epe, B; Greinert, R; Hoffmann-Dörr, S; Volkmer, B1
Abdel-Malek, ZA; Babcock, G; Hauser, JE; Ito, S; Kadekaro, AL; Kavanagh, RJ; Rao, MB; Schwemberger, S; Terzieva, S; Wakamatsu, K1
Gaube, S; Gilbertz, KP; Kerkmann, U; Placzek, M; Przybilla, B1
Cassidy, P; Cotter, MA; Florell, SR; Grossman, D; Jenkins, N; Leachman, S; Robinette, K; Samlowski, WE; Thomas, J1
Granstein, RD; Sober, AJ1
Hill, HZ; Setlow, RB1
Ahmed, FE; Setlow, RB1
Kvam, E; Tyrrell, RM1
Bykov, VJ; Hemminki, K; Jansen, CT; Snellman, E; Xu, G1
Kusewitt, DF; Ley, RD; Reeve, VE1
Meador, JA; Mitchell, DL; Walter, RB1
Hemminki, K; Jansen, CT; Snellman, E; Zhao, C1
Hill, HZ; Huselton, CA1
Bootsma, D; Bos, JL; Hoeijmakers, JH; Keijzer, W; Langeveld, JC; Mulder, MP; Smit, EM1
Boyle, JM; Müller, H; Roth, M1

Reviews

8 review(s) available for pyrimidine dimers and Malignant Melanoma

ArticleYear
Molecular Mechanisms of UVA-Induced Melanoma.
    Journal of environmental pathology, toxicology and oncology : official organ of the International Society for Environmental Toxicology and Cancer, 2017, Volume: 36, Issue:3

    Topics: DNA Damage; Female; Humans; Male; Melanins; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2017
Nucleotide Excision Repair and Vitamin D--Relevance for Skin Cancer Therapy.
    International journal of molecular sciences, 2016, Apr-06, Volume: 17, Issue:4

    Topics: Animals; DNA Damage; DNA Repair; Humans; Melanoma; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Vitamin D; Vitamins

2016
Chemical excitation of electrons: A dark path to melanoma.
    DNA repair, 2016, Volume: 44

    Topics: DNA Damage; Electrons; Humans; Keratinocytes; Melanins; Melanoma; NADPH Oxidases; Neoplasms, Radiation-Induced; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunlight; Superoxides; Ultraviolet Rays

2016
Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis.
    Photochemistry and photobiology, 2017, Volume: 93, Issue:1

    Topics: Cyclic AMP; DNA Repair; Humans; Melanocortins; Melanocytes; Melanoma; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Signal Transduction; Ultraviolet Rays; United States; Xeroderma Pigmentosum

2017
UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer.
    Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology, 2012, Volume: 11, Issue:1

    Topics: DNA Damage; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2012
Mutations induced by ultraviolet light.
    Mutation research, 2005, Apr-01, Volume: 571, Issue:1-2

    Topics: 5-Methylcytosine; Animals; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2005
Current concepts in ultraviolet carcinogenesis.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1982, Volume: 170, Issue:2

    Topics: Aging; Animals; Antioxidants; beta Carotene; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carotenoids; DNA; Female; Geography; Humans; Male; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Sex Factors; Skin Neoplasms; Ultraviolet Rays; Vitamin A

1982
Photobiology of Monodelphis domestica.
    Developmental and comparative immunology, 2000, Volume: 24, Issue:5

    Topics: Animals; Cornea; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; DNA Repair; Eye Neoplasms; Melanoma; Mice; Mice, Nude; Opossums; Oxazolone; Photobiology; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Urocanic Acid

2000

Trials

1 trial(s) available for pyrimidine dimers and Malignant Melanoma

ArticleYear
The effect of MC1R variants and sunscreen on the response of human melanocytes in vivo to ultraviolet radiation and implications for melanoma.
    Pigment cell & melanoma research, 2013, Volume: 26, Issue:6

    Topics: Adult; Apoptosis; Caspase 3; Cell Count; Cell Proliferation; DNA Damage; Erythema; Female; Fluorescent Antibody Technique; Genetic Variation; Humans; Male; Melanocytes; Melanoma; Phenotype; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Sunbathing; Sunscreening Agents; Tumor Suppressor Protein p53; Ultraviolet Rays

2013

Other Studies

37 other study(ies) available for pyrimidine dimers and Malignant Melanoma

ArticleYear
CTCF binding modulates UV damage formation to promote mutation hot spots in melanoma.
    The EMBO journal, 2021, 10-18, Volume: 40, Issue:20

    Topics: Binding Sites; Binding, Competitive; CCCTC-Binding Factor; Cell Line, Tumor; DNA Damage; DNA Repair; Gene Expression; Humans; Melanoma; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Serine-Threonine Kinases; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2021
Detecting recurrent passenger mutations in melanoma by targeted UV damage sequencing.
    Nature communications, 2023, 05-11, Volume: 14, Issue:1

    Topics: DNA Damage; Humans; Melanocytes; Melanoma; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2023
Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 10-08, Volume: 116, Issue:41

    Topics: Cell Line, Tumor; Computational Biology; DNA Damage; DNA Methylation; Genetic Variation; Genome, Human; Humans; Melanoma; Mutation; Promoter Regions, Genetic; Pyrimidine Dimers; Ultraviolet Rays

2019
Genomic sites hypersensitive to ultraviolet radiation.
    Proceedings of the National Academy of Sciences of the United States of America, 2019, 11-26, Volume: 116, Issue:48

    Topics: 5' Untranslated Regions; Cells, Cultured; DNA Damage; Fibroblasts; Gene Expression Regulation; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Melanocytes; Melanoma; Mutation; Promoter Regions, Genetic; Protein Biosynthesis; Pyrimidine Dimers; Pyrimidine Nucleotides; Skin Neoplasms; TOR Serine-Threonine Kinases; Ultraviolet Rays

2019
Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites.
    Nucleic acids research, 2021, 01-25, Volume: 49, Issue:2

    Topics: Binding Sites; Chromosome Mapping; DNA Damage; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Mutagenesis; Mutation; Pyrimidine Dimers; Skin Neoplasms; Transcription Factors; Ultraviolet Rays; Whole Genome Sequencing

2021
Inhibitors of Nucleotide Excision Repair Decrease UVB-Induced Mutagenesis-An In Vitro Study.
    International journal of molecular sciences, 2021, Feb-06, Volume: 22, Issue:4

    Topics: Animals; Arsenic Trioxide; Autophagy; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Transformed; Cell Survival; CHO Cells; Cricetulus; DNA Damage; DNA Repair; HaCaT Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Melanoma; Mutation Rate; Pyrimidine Dimers; Resveratrol; Skin; Skin Neoplasms; Spironolactone; Ultraviolet Rays

2021
The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing.
    Science advances, 2021, Volume: 7, Issue:31

    Topics: Cytosine; Deamination; DNA Damage; Humans; Melanoma; Mutation; Pyrimidine Dimers; Ultraviolet Rays

2021
Photodynamic therapy does not induce cyclobutane pyrimidine dimers in the presence of melanin.
    Photodiagnosis and photodynamic therapy, 2018, Volume: 22

    Topics: Dihematoporphyrin Ether; DNA Damage; Enzyme-Linked Immunosorbent Assay; Humans; Melanins; Melanocytes; Melanoma; Photochemotherapy; Photosensitizing Agents; Pyrimidine Dimers; Ultraviolet Rays

2018
ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma.
    Nature communications, 2018, 07-06, Volume: 9, Issue:1

    Topics: Base Sequence; Binding Sites; DNA; Humans; Melanoma; Models, Biological; Mutagenesis; Mutation; Nucleic Acid Conformation; Protein Binding; Proto-Oncogene Protein c-ets-1; Pyrimidine Dimers; Ultraviolet Rays

2018
Nucleosome positions establish an extended mutation signature in melanoma.
    PLoS genetics, 2018, Volume: 14, Issue:11

    Topics: Chromatin; DNA Repair; DNA, Neoplasm; Female; Genome, Human; Histone Code; Humans; Male; Melanoma; Models, Genetic; Mutation; Neoplasms, Radiation-Induced; Nucleosomes; Prostatic Neoplasms; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2018
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers.
    PLoS genetics, 2018, Volume: 14, Issue:12

    Topics: Base Sequence; Binding Sites; Cell Line, Tumor; DNA Damage; DNA, Neoplasm; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Promoter Regions, Genetic; Proto-Oncogene Proteins c-ets; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Whole Genome Sequencing

2018
SerpinB2 is involved in cellular response upon UV irradiation.
    Scientific reports, 2019, 02-26, Volume: 9, Issue:1

    Topics: Bone Neoplasms; Carcinoma, Basal Cell; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Humans; Melanoma; Osteosarcoma; Plasminogen Activator Inhibitor 2; Pyrimidine Dimers; Tumor Cells, Cultured; Ultraviolet Rays

2019
Biochemical reconstitution of UV-induced mutational processes.
    Nucleic acids research, 2019, 07-26, Volume: 47, Issue:13

    Topics: 5-Methylcytosine; Cell-Free System; Cytosine; Deamination; DNA Damage; DNA Replication; DNA-Cytosine Methylases; DNA-Directed DNA Polymerase; DNA, Neoplasm; DNA, Single-Stranded; Humans; Melanoma; Models, Genetic; Mutagenesis; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Transcriptome; Ultraviolet Rays

2019
Biomolecules. The dark side of sunlight and melanoma.
    Science (New York, N.Y.), 2015, Feb-20, Volume: 347, Issue:6224

    Topics: Animals; DNA; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms

2015
Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.
    Science (New York, N.Y.), 2015, Feb-20, Volume: 347, Issue:6224

    Topics: Animals; Cells, Cultured; Cytosine; DNA; DNA Damage; Energy Transfer; Humans; Melanins; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Mutagenesis; Mutation; Neoplasms, Radiation-Induced; Photons; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Skin Neoplasms; Sunlight; Thymine; Ultraviolet Rays

2015
Dark CPDs and photocarcinogenesis: the party continues after the lights go out.
    Pigment cell & melanoma research, 2015, Volume: 28, Issue:4

    Topics: Animals; DNA; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms

2015
Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines.
    Pigment cell & melanoma research, 2016, Volume: 29, Issue:1

    Topics: Biomarkers; Cell Line; Checkpoint Kinase 1; Diploidy; DNA Damage; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Melanins; Melanocytes; Melanoma; Phosphorylation; Protein Kinases; Pyrimidine Dimers; S Phase Cell Cycle Checkpoints; Ultraviolet Rays

2016
Inhibition of the RhoA GTPase Activity Increases Sensitivity of Melanoma Cells to UV Radiation Effects.
    Oxidative medicine and cellular longevity, 2016, Volume: 2016

    Topics: Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Comet Assay; DNA Damage; DNA Repair; Glutathione Transferase; GTP-Binding Proteins; Humans; Intracellular Signaling Peptides and Proteins; Melanoma; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrimidine Dimers; rhoA GTP-Binding Protein; Skin Neoplasms; Ultraviolet Rays

2016
Photosensitized rose Bengal-induced phototoxicity on human melanoma cell line under natural sunlight exposure.
    Journal of photochemistry and photobiology. B, Biology, 2016, Volume: 156

    Topics: Caspase 3; Cell Line, Tumor; DNA Damage; Humans; Linoleic Acid; Melanoma; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Oxidation-Reduction; Pyrimidine Dimers; Reactive Oxygen Species; Rose Bengal; Sunlight

2016
UV-induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis.
    Toxicologic pathology, 2016, Volume: 44, Issue:4

    Topics: Animals; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Mice; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2016
Further assessment of exome-wide UVR footprints in melanoma and their possible relevance.
    Molecular carcinogenesis, 2017, Volume: 56, Issue:6

    Topics: Animals; Exome; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Ultraviolet Rays

2017
Enhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4(R24C/R24C)/Tyr-Nras(Q61K) mice following neonatal UVR.
    Pigment cell & melanoma research, 2010, Volume: 23, Issue:1

    Topics: Administration, Topical; Animals; Animals, Newborn; Antineoplastic Agents; Cell Proliferation; Cyclin-Dependent Kinase 4; Deoxyribonuclease (Pyrimidine Dimer); Disease Models, Animal; DNA Damage; DNA Repair; Keratinocytes; Melanocytes; Melanoma; Mice; Mice, Transgenic; Pyrimidine Dimers; Skin; Skin Neoplasms; Time; Treatment Outcome; Ultraviolet Rays; Up-Regulation; Viral Proteins

2010
Different types of DNA damage play different roles in the etiology of sunlight-induced melanoma.
    Pigment cell & melanoma research, 2011, Volume: 24, Issue:1

    Topics: Animals; Cyprinodontiformes; Disease Models, Animal; DNA Damage; Humans; Melanoma; Models, Biological; Mutation; Pyrimidine Dimers; Reactive Oxygen Species; Skin Neoplasms; Sunlight; Ultraviolet Rays

2011
Is UV-induced mutation formation in melanocytes different from other skin cells?
    Pigment cell & melanoma research, 2011, Volume: 24, Issue:1

    Topics: Animals; DNA Damage; DNA Repair; Fibroblasts; Humans; Keratinocytes; Melanocytes; Melanoma; Mutagenesis; Mutation; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2011
Visible light (>395 nm) causes micronuclei formation in mammalian cells without generation of cyclobutane pyrimidine dimers.
    Mutation research, 2005, May-02, Volume: 572, Issue:1-2

    Topics: Animals; Humans; Light; Male; Melanoma; Micronucleus Tests; Middle Aged; Pyrimidine Dimers; Tumor Cells, Cultured

2005
Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes.
    Pigment cell research, 2006, Volume: 19, Issue:4

    Topics: Adult; Apoptosis; Biopsy; Cell Division; Cells, Cultured; DNA Damage; DNA Repair; Humans; Hydrogen Peroxide; Infant, Newborn; Male; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Risk Factors; Skin; Ultraviolet Rays

2006
Effect of ultraviolet (UV) A, UVB or ionizing radiation on the cell cycle of human melanoma cells.
    The British journal of dermatology, 2007, Volume: 156, Issue:5

    Topics: Cell Cycle; DNA Damage; Humans; Melanoma; Pyrimidine Dimers; Radiation, Ionizing; Skin Neoplasms; Ultraviolet Rays

2007
N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of ultraviolet-induced melanoma in mice.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2007, Oct-01, Volume: 13, Issue:19

    Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Humans; Male; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Radiation-Induced; Oxidative Stress; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Ultraviolet Rays

2007
Comparative action spectra for pyrimidine dimer formation in cloudman S91 mouse melanoma and EMT6 mouse mammary carcinoma cells.
    Photochemistry and photobiology, 1982, Volume: 35, Issue:5

    Topics: Animals; Cell Line; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Melanoma; Mice; Neoplasms, Experimental; Pyrimidine Dimers; Ultraviolet Rays

1982
Ultraviolet radiation-induced DNA damage and its photorepair in the skin of the platyfish Xiphophorus.
    Cancer research, 1993, May-15, Volume: 53, Issue:10 Suppl

    Topics: Animals; Cyprinodontiformes; Disease Models, Animal; DNA; DNA Damage; DNA Repair; Female; Fibroblasts; Humans; Male; Melanins; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Physiological Phenomena; Ultraviolet Rays

1993
Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation.
    Carcinogenesis, 1997, Volume: 18, Issue:12

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Cells, Cultured; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Melanoma; Oxidation-Reduction; Pyrimidine Dimers; Skin; Skin Neoplasms; Spectrum Analysis; Ultraviolet Rays

1997
Cutaneous melanoma patients have normal repair kinetics of ultraviolet-induced DNA repair in skin in situ.
    The Journal of investigative dermatology, 2000, Volume: 114, Issue:4

    Topics: Adult; DNA Repair; Female; Humans; Male; Melanoma; Middle Aged; Pyrimidine Dimers; Skin; Skin Neoplasms; Time Factors; Ultraviolet Rays

2000
Induction, distribution and repair of UV photodamage in the platyfish, Xiphophorus signum.
    Photochemistry and photobiology, 2000, Volume: 72, Issue:2

    Topics: Animals; Cyprinodontiformes; DNA Repair; Melanoma; Neoplasms, Radiation-Induced; Photobiology; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays

2000
In situ repair of cyclobutane pyrimidine dimers in skin and melanocytic nevi of cutaneous melanoma patients.
    International journal of cancer, 2002, Mar-20, Volume: 98, Issue:3

    Topics: Adult; Biopsy; Chromatography, High Pressure Liquid; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Middle Aged; Nevus, Pigmented; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays

2002
Melanin photosensitizes ultraviolet light (UVC) DNA damage in pigmented cells.
    Environmental and molecular mutagenesis, 1990, Volume: 16, Issue:1

    Topics: Animals; DNA; DNA Damage; In Vitro Techniques; Mass Spectrometry; Melanins; Melanoma; Mice; Pyrimidine Dimers; Tumor Cells, Cultured; Ultraviolet Rays

1990
Establishment and characterization of a melanoma cell line from a xeroderma pigmentosum patient: activation of N-ras at a potential pyrimidine dimer site.
    Cancer research, 1989, Mar-01, Volume: 49, Issue:5

    Topics: Animals; Child; Chromosome Aberrations; DNA Repair; Genes, ras; Humans; Melanoma; Mice; Mutation; Phenotype; Pyrimidine Dimers; Skin Neoplasms; Tumor Cells, Cultured; Ultraviolet Rays; Xeroderma Pigmentosum

1989
Immunochemical determination of an initial step in thymine dimer excision repair in xeroderma pigmentosum variant fibroblasts and biopsy material from the normal population and patients with basal cell carcinoma and melanoma.
    Carcinogenesis, 1987, Volume: 8, Issue:9

    Topics: Adult; Antibodies, Monoclonal; Carcinoma, Basal Cell; DNA; DNA Repair; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Male; Melanoma; Middle Aged; Mutation; Pyrimidine Dimers; Skin Neoplasms; Xeroderma Pigmentosum

1987