pyrimidine dimers has been researched along with Malignant Melanoma in 46 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 4 (8.70) | 18.7374 |
1990's | 3 (6.52) | 18.2507 |
2000's | 9 (19.57) | 29.6817 |
2010's | 25 (54.35) | 24.3611 |
2020's | 5 (10.87) | 2.80 |
Authors | Studies |
---|---|
Albrecht, AV; Bohm, KA; Emehiser, RG; Hrdlicka, PJ; Mao, P; Poon, GMK; Roberts, SA; Sivapragasam, S; Stark, B; Wyrick, JJ | 1 |
Poon, GMK; Selvam, K; Sivapragasam, S; Wyrick, JJ | 1 |
Boström, M; Elliott, K; Larsson, E; Lindberg, M | 1 |
Brash, DE; Han, L; Knight, J; Kornacker, K; Mehta, S; Palmatier, MA; Premi, S; Zhao, D | 1 |
Frigola, J; Gonzalez-Perez, A; Lopez-Bigas, N; Sabarinathan, R | 1 |
Emri, G; Fidrus, E; Hegedűs, C; Janka, EA; Paragh, G; Remenyik, É | 1 |
Jin, SG; Johnson, J; Li, P; Pettinga, D; Pfeifer, GP | 1 |
Duoji, G; Grigalavicius, M; Jie, D; Juzeniene, A; Pudroma, X | 1 |
Bellnier, D; Fidrus, E; Mudambi, S; Paragh, G; Pera, P; Remenyik, E; Shafirstein, G; Washington, D | 1 |
Brown, AJ; Esaki, S; Lockwood, S; Mao, P; Poon, GMK; Roberts, SA; Smerdon, MJ; Wyrick, JJ | 1 |
Brown, AJ; Mao, P; Roberts, SA; Smerdon, MJ; Wyrick, JJ | 1 |
Boström, M; Clausen, AR; Elliott, K; Filges, S; Larsson, E; Lindberg, M; Ståhlberg, A; Van den Eynden, J | 1 |
Bíró, T; Boros, IM; Borsos, BN; Buzas, K; Coin, F; Hudacsek, VV; Kovács, I; Majoros, H; Nagy, Z; Pankotai, T; Ujfaludi, Z | 1 |
Chen, Y; Sugiyama, T | 1 |
Boyce, Z; Hacker, E; Hayward, NK; Kimlin, MG; Pollak, T; Vaartjes, SA; Whiteman, DC; Wockner, L | 1 |
Taylor, JS | 1 |
Bacchiocchi, A; Bechara, EJ; Brash, DE; Douki, T; Halaban, R; Mano, CM; Premi, S; Wakamatsu, K; Wallisch, S; Weiner, AB | 1 |
Abdel-Malek, ZA; Cassidy, P | 1 |
Carson, C; Chastain, PD; Cordeiro-Stone, M; Gibbs-Flournoy, E; Ibrahim, JG; Kaufmann, WK; McNulty, JJ; Mitchell, DL; Rao, S; Simpson, DA; Sproul, CD; Thomas, NE; Zhou, Y | 1 |
Costa, ET; Espinha, G; Forti, FL; Osaki, JH | 1 |
Amar, SK; Chaturvedi, RK; Dwivedi, A; Goyal, S; Kushwaha, HN; Mujtaba, SF; Ray, RS; Srivastav, AK; Verma, A | 1 |
Brash, DE | 1 |
Blasiak, J; Pawlowska, E; Wysokinski, D | 1 |
Brash, DE; Premi, S | 1 |
D'Orazio, JA; Jarrett, SG | 1 |
Mukhopadhyay, P; Roberts, JA; Walker, GJ | 1 |
Fahey, P; Hacker, E; Hayward, N; Muller, HK; Walker, G | 1 |
Fernandez, AA; Mitchell, DL | 1 |
Rünger, TM | 1 |
Besaratinia, A; Pfeifer, GP | 1 |
Besaratinia, A; Pfeifer, GP; You, YH | 1 |
Epe, B; Greinert, R; Hoffmann-Dörr, S; Volkmer, B | 1 |
Abdel-Malek, ZA; Babcock, G; Hauser, JE; Ito, S; Kadekaro, AL; Kavanagh, RJ; Rao, MB; Schwemberger, S; Terzieva, S; Wakamatsu, K | 1 |
Gaube, S; Gilbertz, KP; Kerkmann, U; Placzek, M; Przybilla, B | 1 |
Cassidy, P; Cotter, MA; Florell, SR; Grossman, D; Jenkins, N; Leachman, S; Robinette, K; Samlowski, WE; Thomas, J | 1 |
Granstein, RD; Sober, AJ | 1 |
Hill, HZ; Setlow, RB | 1 |
Ahmed, FE; Setlow, RB | 1 |
Kvam, E; Tyrrell, RM | 1 |
Bykov, VJ; Hemminki, K; Jansen, CT; Snellman, E; Xu, G | 1 |
Kusewitt, DF; Ley, RD; Reeve, VE | 1 |
Meador, JA; Mitchell, DL; Walter, RB | 1 |
Hemminki, K; Jansen, CT; Snellman, E; Zhao, C | 1 |
Hill, HZ; Huselton, CA | 1 |
Bootsma, D; Bos, JL; Hoeijmakers, JH; Keijzer, W; Langeveld, JC; Mulder, MP; Smit, EM | 1 |
Boyle, JM; Müller, H; Roth, M | 1 |
8 review(s) available for pyrimidine dimers and Malignant Melanoma
Article | Year |
---|---|
Molecular Mechanisms of UVA-Induced Melanoma.
Topics: DNA Damage; Female; Humans; Male; Melanins; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2017 |
Nucleotide Excision Repair and Vitamin D--Relevance for Skin Cancer Therapy.
Topics: Animals; DNA Damage; DNA Repair; Humans; Melanoma; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Vitamin D; Vitamins | 2016 |
Chemical excitation of electrons: A dark path to melanoma.
Topics: DNA Damage; Electrons; Humans; Keratinocytes; Melanins; Melanoma; NADPH Oxidases; Neoplasms, Radiation-Induced; Nitric Oxide; Nitric Oxide Synthase; Peroxynitrous Acid; Pyrimidine Dimers; Skin; Skin Neoplasms; Sunlight; Superoxides; Ultraviolet Rays | 2016 |
Hormonal Regulation of the Repair of UV Photoproducts in Melanocytes by the Melanocortin Signaling Axis.
Topics: Cyclic AMP; DNA Repair; Humans; Melanocortins; Melanocytes; Melanoma; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Signal Transduction; Ultraviolet Rays; United States; Xeroderma Pigmentosum | 2017 |
UV wavelength-dependent DNA damage and human non-melanoma and melanoma skin cancer.
Topics: DNA Damage; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2012 |
Mutations induced by ultraviolet light.
Topics: 5-Methylcytosine; Animals; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2005 |
Current concepts in ultraviolet carcinogenesis.
Topics: Aging; Animals; Antioxidants; beta Carotene; Carcinogens; Carcinoma, Basal Cell; Carcinoma, Squamous Cell; Carotenoids; DNA; Female; Geography; Humans; Male; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Sex Factors; Skin Neoplasms; Ultraviolet Rays; Vitamin A | 1982 |
Photobiology of Monodelphis domestica.
Topics: Animals; Cornea; Dermatitis, Contact; Dinitrofluorobenzene; Disease Models, Animal; DNA Repair; Eye Neoplasms; Melanoma; Mice; Mice, Nude; Opossums; Oxazolone; Photobiology; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays; Urocanic Acid | 2000 |
1 trial(s) available for pyrimidine dimers and Malignant Melanoma
Article | Year |
---|---|
The effect of MC1R variants and sunscreen on the response of human melanocytes in vivo to ultraviolet radiation and implications for melanoma.
Topics: Adult; Apoptosis; Caspase 3; Cell Count; Cell Proliferation; DNA Damage; Erythema; Female; Fluorescent Antibody Technique; Genetic Variation; Humans; Male; Melanocytes; Melanoma; Phenotype; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Sunbathing; Sunscreening Agents; Tumor Suppressor Protein p53; Ultraviolet Rays | 2013 |
37 other study(ies) available for pyrimidine dimers and Malignant Melanoma
Article | Year |
---|---|
CTCF binding modulates UV damage formation to promote mutation hot spots in melanoma.
Topics: Binding Sites; Binding, Competitive; CCCTC-Binding Factor; Cell Line, Tumor; DNA Damage; DNA Repair; Gene Expression; Humans; Melanoma; Molecular Dynamics Simulation; Mutation; Protein Binding; Protein Serine-Threonine Kinases; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2021 |
Detecting recurrent passenger mutations in melanoma by targeted UV damage sequencing.
Topics: DNA Damage; Humans; Melanocytes; Melanoma; Mutation; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2023 |
Intragenomic variability and extended sequence patterns in the mutational signature of ultraviolet light.
Topics: Cell Line, Tumor; Computational Biology; DNA Damage; DNA Methylation; Genetic Variation; Genome, Human; Humans; Melanoma; Mutation; Promoter Regions, Genetic; Pyrimidine Dimers; Ultraviolet Rays | 2019 |
Genomic sites hypersensitive to ultraviolet radiation.
Topics: 5' Untranslated Regions; Cells, Cultured; DNA Damage; Fibroblasts; Gene Expression Regulation; Genome, Human; High-Throughput Nucleotide Sequencing; Humans; Melanocytes; Melanoma; Mutation; Promoter Regions, Genetic; Protein Biosynthesis; Pyrimidine Dimers; Pyrimidine Nucleotides; Skin Neoplasms; TOR Serine-Threonine Kinases; Ultraviolet Rays | 2019 |
Variable interplay of UV-induced DNA damage and repair at transcription factor binding sites.
Topics: Binding Sites; Chromosome Mapping; DNA Damage; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Mutagenesis; Mutation; Pyrimidine Dimers; Skin Neoplasms; Transcription Factors; Ultraviolet Rays; Whole Genome Sequencing | 2021 |
Inhibitors of Nucleotide Excision Repair Decrease UVB-Induced Mutagenesis-An In Vitro Study.
Topics: Animals; Arsenic Trioxide; Autophagy; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Transformed; Cell Survival; CHO Cells; Cricetulus; DNA Damage; DNA Repair; HaCaT Cells; Humans; Hypoxanthine Phosphoribosyltransferase; Melanoma; Mutation Rate; Pyrimidine Dimers; Resveratrol; Skin; Skin Neoplasms; Spironolactone; Ultraviolet Rays | 2021 |
The major mechanism of melanoma mutations is based on deamination of cytosine in pyrimidine dimers as determined by circle damage sequencing.
Topics: Cytosine; Deamination; DNA Damage; Humans; Melanoma; Mutation; Pyrimidine Dimers; Ultraviolet Rays | 2021 |
Photodynamic therapy does not induce cyclobutane pyrimidine dimers in the presence of melanin.
Topics: Dihematoporphyrin Ether; DNA Damage; Enzyme-Linked Immunosorbent Assay; Humans; Melanins; Melanocytes; Melanoma; Photochemotherapy; Photosensitizing Agents; Pyrimidine Dimers; Ultraviolet Rays | 2018 |
ETS transcription factors induce a unique UV damage signature that drives recurrent mutagenesis in melanoma.
Topics: Base Sequence; Binding Sites; DNA; Humans; Melanoma; Models, Biological; Mutagenesis; Mutation; Nucleic Acid Conformation; Protein Binding; Proto-Oncogene Protein c-ets-1; Pyrimidine Dimers; Ultraviolet Rays | 2018 |
Nucleosome positions establish an extended mutation signature in melanoma.
Topics: Chromatin; DNA Repair; DNA, Neoplasm; Female; Genome, Human; Histone Code; Humans; Male; Melanoma; Models, Genetic; Mutation; Neoplasms, Radiation-Induced; Nucleosomes; Prostatic Neoplasms; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2018 |
Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers.
Topics: Base Sequence; Binding Sites; Cell Line, Tumor; DNA Damage; DNA, Neoplasm; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Promoter Regions, Genetic; Proto-Oncogene Proteins c-ets; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays; Whole Genome Sequencing | 2018 |
SerpinB2 is involved in cellular response upon UV irradiation.
Topics: Bone Neoplasms; Carcinoma, Basal Cell; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Humans; Melanoma; Osteosarcoma; Plasminogen Activator Inhibitor 2; Pyrimidine Dimers; Tumor Cells, Cultured; Ultraviolet Rays | 2019 |
Biochemical reconstitution of UV-induced mutational processes.
Topics: 5-Methylcytosine; Cell-Free System; Cytosine; Deamination; DNA Damage; DNA Replication; DNA-Cytosine Methylases; DNA-Directed DNA Polymerase; DNA, Neoplasm; DNA, Single-Stranded; Humans; Melanoma; Models, Genetic; Mutagenesis; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms; Transcriptome; Ultraviolet Rays | 2019 |
Biomolecules. The dark side of sunlight and melanoma.
Topics: Animals; DNA; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms | 2015 |
Photochemistry. Chemiexcitation of melanin derivatives induces DNA photoproducts long after UV exposure.
Topics: Animals; Cells, Cultured; Cytosine; DNA; DNA Damage; Energy Transfer; Humans; Melanins; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Mutagenesis; Mutation; Neoplasms, Radiation-Induced; Photons; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Skin Neoplasms; Sunlight; Thymine; Ultraviolet Rays | 2015 |
Dark CPDs and photocarcinogenesis: the party continues after the lights go out.
Topics: Animals; DNA; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin Neoplasms | 2015 |
Effective intra-S checkpoint responses to UVC in primary human melanocytes and melanoma cell lines.
Topics: Biomarkers; Cell Line; Checkpoint Kinase 1; Diploidy; DNA Damage; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Melanins; Melanocytes; Melanoma; Phosphorylation; Protein Kinases; Pyrimidine Dimers; S Phase Cell Cycle Checkpoints; Ultraviolet Rays | 2016 |
Inhibition of the RhoA GTPase Activity Increases Sensitivity of Melanoma Cells to UV Radiation Effects.
Topics: Apoptosis Regulatory Proteins; Cell Line, Tumor; Cell Movement; Cell Proliferation; Comet Assay; DNA Damage; DNA Repair; Glutathione Transferase; GTP-Binding Proteins; Humans; Intracellular Signaling Peptides and Proteins; Melanoma; Microscopy, Fluorescence; Neoplasm Invasiveness; Neoplasm Metastasis; Pyrimidine Dimers; rhoA GTP-Binding Protein; Skin Neoplasms; Ultraviolet Rays | 2016 |
Photosensitized rose Bengal-induced phototoxicity on human melanoma cell line under natural sunlight exposure.
Topics: Caspase 3; Cell Line, Tumor; DNA Damage; Humans; Linoleic Acid; Melanoma; Membrane Potential, Mitochondrial; Microscopy, Electron, Transmission; Oxidation-Reduction; Pyrimidine Dimers; Reactive Oxygen Species; Rose Bengal; Sunlight | 2016 |
UV-induced Melanin Chemiexcitation: A New Mode of Melanoma Pathogenesis.
Topics: Animals; DNA Damage; Humans; Melanins; Melanocytes; Melanoma; Mice; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2016 |
Further assessment of exome-wide UVR footprints in melanoma and their possible relevance.
Topics: Animals; Exome; Humans; Melanoma; Mutation; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Ultraviolet Rays | 2017 |
Enhancement of DNA repair using topical T4 endonuclease V does not inhibit melanoma formation in Cdk4(R24C/R24C)/Tyr-Nras(Q61K) mice following neonatal UVR.
Topics: Administration, Topical; Animals; Animals, Newborn; Antineoplastic Agents; Cell Proliferation; Cyclin-Dependent Kinase 4; Deoxyribonuclease (Pyrimidine Dimer); Disease Models, Animal; DNA Damage; DNA Repair; Keratinocytes; Melanocytes; Melanoma; Mice; Mice, Transgenic; Pyrimidine Dimers; Skin; Skin Neoplasms; Time; Treatment Outcome; Ultraviolet Rays; Up-Regulation; Viral Proteins | 2010 |
Different types of DNA damage play different roles in the etiology of sunlight-induced melanoma.
Topics: Animals; Cyprinodontiformes; Disease Models, Animal; DNA Damage; Humans; Melanoma; Models, Biological; Mutation; Pyrimidine Dimers; Reactive Oxygen Species; Skin Neoplasms; Sunlight; Ultraviolet Rays | 2011 |
Is UV-induced mutation formation in melanocytes different from other skin cells?
Topics: Animals; DNA Damage; DNA Repair; Fibroblasts; Humans; Keratinocytes; Melanocytes; Melanoma; Mutagenesis; Mutation; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays | 2011 |
Visible light (>395 nm) causes micronuclei formation in mammalian cells without generation of cyclobutane pyrimidine dimers.
Topics: Animals; Humans; Light; Male; Melanoma; Micronucleus Tests; Middle Aged; Pyrimidine Dimers; Tumor Cells, Cultured | 2005 |
Melanin content and MC1R function independently affect UVR-induced DNA damage in cultured human melanocytes.
Topics: Adult; Apoptosis; Biopsy; Cell Division; Cells, Cultured; DNA Damage; DNA Repair; Humans; Hydrogen Peroxide; Infant, Newborn; Male; Melanins; Melanocytes; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Receptor, Melanocortin, Type 1; Risk Factors; Skin; Ultraviolet Rays | 2006 |
Effect of ultraviolet (UV) A, UVB or ionizing radiation on the cell cycle of human melanoma cells.
Topics: Cell Cycle; DNA Damage; Humans; Melanoma; Pyrimidine Dimers; Radiation, Ionizing; Skin Neoplasms; Ultraviolet Rays | 2007 |
N-acetylcysteine protects melanocytes against oxidative stress/damage and delays onset of ultraviolet-induced melanoma in mice.
Topics: Acetylcysteine; Animals; Anticarcinogenic Agents; Humans; Male; Melanocytes; Melanoma; Mice; Mice, Inbred C57BL; Neoplasms, Radiation-Induced; Oxidative Stress; Pyrimidine Dimers; Reactive Oxygen Species; Skin; Ultraviolet Rays | 2007 |
Comparative action spectra for pyrimidine dimer formation in cloudman S91 mouse melanoma and EMT6 mouse mammary carcinoma cells.
Topics: Animals; Cell Line; DNA, Neoplasm; Female; Mammary Neoplasms, Experimental; Melanoma; Mice; Neoplasms, Experimental; Pyrimidine Dimers; Ultraviolet Rays | 1982 |
Ultraviolet radiation-induced DNA damage and its photorepair in the skin of the platyfish Xiphophorus.
Topics: Animals; Cyprinodontiformes; Disease Models, Animal; DNA; DNA Damage; DNA Repair; Female; Fibroblasts; Humans; Male; Melanins; Melanoma; Neoplasms, Radiation-Induced; Pyrimidine Dimers; Skin; Skin Physiological Phenomena; Ultraviolet Rays | 1993 |
Induction of oxidative DNA base damage in human skin cells by UV and near visible radiation.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Cells, Cultured; Deoxyguanosine; DNA Damage; Dose-Response Relationship, Radiation; Fibroblasts; Humans; Melanoma; Oxidation-Reduction; Pyrimidine Dimers; Skin; Skin Neoplasms; Spectrum Analysis; Ultraviolet Rays | 1997 |
Cutaneous melanoma patients have normal repair kinetics of ultraviolet-induced DNA repair in skin in situ.
Topics: Adult; DNA Repair; Female; Humans; Male; Melanoma; Middle Aged; Pyrimidine Dimers; Skin; Skin Neoplasms; Time Factors; Ultraviolet Rays | 2000 |
Induction, distribution and repair of UV photodamage in the platyfish, Xiphophorus signum.
Topics: Animals; Cyprinodontiformes; DNA Repair; Melanoma; Neoplasms, Radiation-Induced; Photobiology; Pyrimidine Dimers; Skin Neoplasms; Ultraviolet Rays | 2000 |
In situ repair of cyclobutane pyrimidine dimers in skin and melanocytic nevi of cutaneous melanoma patients.
Topics: Adult; Biopsy; Chromatography, High Pressure Liquid; DNA Repair; DNA, Neoplasm; Humans; Melanoma; Middle Aged; Nevus, Pigmented; Pyrimidine Dimers; Skin; Skin Neoplasms; Ultraviolet Rays | 2002 |
Melanin photosensitizes ultraviolet light (UVC) DNA damage in pigmented cells.
Topics: Animals; DNA; DNA Damage; In Vitro Techniques; Mass Spectrometry; Melanins; Melanoma; Mice; Pyrimidine Dimers; Tumor Cells, Cultured; Ultraviolet Rays | 1990 |
Establishment and characterization of a melanoma cell line from a xeroderma pigmentosum patient: activation of N-ras at a potential pyrimidine dimer site.
Topics: Animals; Child; Chromosome Aberrations; DNA Repair; Genes, ras; Humans; Melanoma; Mice; Mutation; Phenotype; Pyrimidine Dimers; Skin Neoplasms; Tumor Cells, Cultured; Ultraviolet Rays; Xeroderma Pigmentosum | 1989 |
Immunochemical determination of an initial step in thymine dimer excision repair in xeroderma pigmentosum variant fibroblasts and biopsy material from the normal population and patients with basal cell carcinoma and melanoma.
Topics: Adult; Antibodies, Monoclonal; Carcinoma, Basal Cell; DNA; DNA Repair; Female; Fibroblasts; Humans; Immunoenzyme Techniques; Male; Melanoma; Middle Aged; Mutation; Pyrimidine Dimers; Skin Neoplasms; Xeroderma Pigmentosum | 1987 |