Page last updated: 2024-08-26

pyrimidine dimers and Cockayne Syndrome

pyrimidine dimers has been researched along with Cockayne Syndrome in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19905 (19.23)18.7374
1990's15 (57.69)18.2507
2000's5 (19.23)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tornaletti, S1
An, J; Huang, Y; Liu, F; Sun, J; Wang, Y; Wu, D; Xu, Q; Yang, T; Zhou, P1
Hanawalt, P; Itoh, T; Matsunaga, T; Nikaido, O; Spivak, G; Yamaizumi, M1
Palitti, F1
Lorenti-Garcia, C; Mosesso, P; Palitti, F; Penna, S; Pepe, G1
Bohr, VA; Evans, MK1
Mayne, LV; Mullenders, LH; Natarajan, AT; van Hoffen, A; van Zeeland, AA; Venema, J2
Kraemer, KH; Parris, CN1
Friedberg, EC; Harada, Y; Itoh, T; Matsunaga, T; Nikaido, O; Shiomi, N; Shiomi, T; Wakasugi, M; Yamaizumi, M1
Bohr, VA; Dianov, GL; Orren, DK1
Artuso, M; English, DR; Hall, J1
Sancar, A; Selby, CP1
Kantor, GJ; Shanower, GA1
Mullenders, LH; Overkamp, MW; van Hees-Stuivenberg, S; van Zeeland, AA; Vreeswijk, MP; Vrieling, H; Westland, BE; Zdzienicka, MZ1
Chevallier-Lagente, O; Mezzina, M; Nikaido, O; Riou, L; Sarasin, A; Stary, A; Taïeb, A; Weeda, G; Zeng, L1
de Jong-Versteeg, A; Kalle, WH; Lehmann, AR; Mullenders, LH; van Hoffen, A; van Zeeland, AA1
Balajee, AS; Bohr, VA; Brosh, RM; Proietti De Santis, L; Selzer, RR; Sunesen, M1
Tuteja, N; Tuteja, R1
Barrett, SF; Kraemer, KH; Robbins, JH; Tarone, RE1
Mayne, LV; Mullenders, LH; Natarajan, AT; van Zeeland, AA; Venema, J1
Bellmann, R; Hirsch-Kauffmann, M; Jaeken, J; Klocker, H; Schwaiger, H; Schweiger, M1
Auer, B; Burtscher, HJ; Hirsch-Kauffmann, M; Klocker, H; Schneider, R; Schweiger, M3
Lam, LH; Reynolds, RJ1

Reviews

5 review(s) available for pyrimidine dimers and Cockayne Syndrome

ArticleYear
DNA repair in mammalian cells: Transcription-coupled DNA repair: directing your effort where it's most needed.
    Cellular and molecular life sciences : CMLS, 2009, Volume: 66, Issue:6

    Topics: Antineoplastic Agents; Apoptosis; Cisplatin; Cockayne Syndrome; DNA Damage; DNA Repair; DNA Repair Enzymes; Humans; Oxidation-Reduction; Pyrimidine Dimers; RNA Polymerase II; Signal Transduction; Transcription, Genetic

2009
Mechanisms of formation of chromosomal aberrations: insights from studies with DNA repair-deficient cells.
    Cytogenetic and genome research, 2004, Volume: 104, Issue:1-4

    Topics: Amanitins; Animals; Apoptosis; Cell Cycle; Cell Line; Chromosome Aberrations; Chromosomes, Human; Cockayne Syndrome; Cricetinae; DNA; DNA Damage; DNA Helicases; DNA Repair; DNA-Binding Proteins; Enzyme Inhibitors; Exodeoxyribonucleases; Genomic Instability; Humans; Neoplastic Syndromes, Hereditary; Pyrimidine Dimers; RecQ Helicases; RNA Polymerase II; Transcription, Genetic; Ultraviolet Rays; Werner Syndrome; Werner Syndrome Helicase

2004
Molecular epidemiology of skin cancers: DNA repair and non-melanocytic skin cancer.
    Annali dell'Istituto superiore di sanita, 1996, Volume: 32, Issue:1

    Topics: Animals; Cell Transformation, Neoplastic; Cocarcinogenesis; Cockayne Syndrome; DNA Damage; DNA Repair; Humans; Incidence; Mammals; Neoplasms, Radiation-Induced; Photosensitivity Disorders; Pyrimidine Dimers; Risk Factors; Skin Neoplasms; Sunlight; Ultraviolet Rays; Xeroderma Pigmentosum

1996
Unraveling DNA repair in human: molecular mechanisms and consequences of repair defect.
    Critical reviews in biochemistry and molecular biology, 2001, Volume: 36, Issue:3

    Topics: Alkylation; Animals; Ataxia Telangiectasia; Base Pair Mismatch; Carbon-Oxygen Lyases; Chromosome Breakage; Chromosome Fragility; Cockayne Syndrome; Cross-Linking Reagents; Deoxyribonuclease IV (Phage T4-Induced); DNA; DNA Adducts; DNA Damage; DNA Glycosylases; DNA Helicases; DNA Repair; DNA-(Apurinic or Apyrimidinic Site) Lyase; DNA-Activated Protein Kinase; DNA-Binding Proteins; Endonucleases; Forecasting; Genes, Recessive; Genetic Complementation Test; Genetic Predisposition to Disease; Hair Diseases; Humans; Intellectual Disability; Mammals; N-Glycosyl Hydrolases; Nail Diseases; Neoplasms; Nuclear Proteins; O(6)-Methylguanine-DNA Methyltransferase; Photochemistry; Photosensitivity Disorders; Protein Serine-Threonine Kinases; Proteins; Pyrimidine Dimers; Transcription Factor TFIIH; Transcription Factors; Transcription Factors, TFII; Ultraviolet Rays; Xeroderma Pigmentosum; Xeroderma Pigmentosum Group D Protein

2001
DNA repair in human cells: biochemistry of the hereditary diseases Fanconi's anaemia and Cockayne syndrome. Tenth Fritz-Lipmann lecture.
    Biological chemistry Hoppe-Seyler, 1986, Volume: 367, Issue:12

    Topics: Anemia, Aplastic; Cells, Cultured; Cockayne Syndrome; DNA Repair; Dwarfism; Fanconi Anemia; Humans; Poly(ADP-ribose) Polymerases; Pyrimidine Dimers; Radioimmunoassay; Transcription, Genetic; Ultraviolet Rays

1986

Other Studies

21 other study(ies) available for pyrimidine dimers and Cockayne Syndrome

ArticleYear
Strand-specific PCR of UV radiation-damaged genomic DNA revealed an essential role of DNA-PKcs in the transcription-coupled repair.
    BMC biochemistry, 2011, Jan-08, Volume: 12

    Topics: Cockayne Syndrome; Cyclin T; Cyclin-Dependent Kinase 9; DNA; DNA Damage; DNA Repair; DNA-Activated Protein Kinase; Genes, myc; HeLa Cells; Humans; Phosphatidylinositol 3-Kinase; Phosphorylation; Polymerase Chain Reaction; Pyrimidine Dimers; RNA Polymerase II; Tetrahydrofolate Dehydrogenase; Transcription, Genetic

2011
Ultraviolet-sensitive syndrome cells are defective in transcription-coupled repair of cyclobutane pyrimidine dimers.
    DNA repair, 2002, Aug-06, Volume: 1, Issue:8

    Topics: alpha-Fetoproteins; Cells, Cultured; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; Fibroblasts; Genes, p53; Humans; Neurofilament Proteins; Pyrimidine Dimers; Radiation Tolerance; RNA; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

2002
Potassium bromate but not X-rays cause unexpectedly elevated levels of DNA breakage similar to those induced by ultraviolet light in Cockayne syndrome (CS-B) fibroblasts.
    Cytogenetic and genome research, 2004, Volume: 104, Issue:1-4

    Topics: Bromates; Chromosomal Instability; Cockayne Syndrome; Comet Assay; DNA; DNA Damage; DNA Repair; Fibroblasts; Guanine; Humans; Oxidation-Reduction; Photochemistry; Pyrimidine Dimers; Radiation Tolerance; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

2004
Gene-specific DNA repair of UV-induced cyclobutane pyrimidine dimers in some cancer-prone and premature-aging human syndromes.
    Mutation research, 1994, Volume: 314, Issue:3

    Topics: Abnormalities, Multiple; Bloom Syndrome; Cell Line; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; Dysplastic Nevus Syndrome; Gardner Syndrome; Globins; Humans; Proto-Oncogene Proteins c-myc; Pyrimidine Dimers; Tetrahydrofolate Dehydrogenase; Ultraviolet Rays

1994
Deficient repair of the transcribed strand of active genes in Cockayne's syndrome cells.
    Nucleic acids research, 1993, Dec-25, Volume: 21, Issue:25

    Topics: Adenosine Deaminase; Cell Line, Transformed; Cells, Cultured; Cockayne Syndrome; DNA Damage; DNA Repair; Fibroblasts; Humans; Pyrimidine Dimers; Simian virus 40; Tetrahydrofolate Dehydrogenase; Transcription, Genetic

1993
Ultraviolet-induced mutations in Cockayne syndrome cells are primarily caused by cyclobutane dimer photoproducts while repair of other photoproducts is normal.
    Proceedings of the National Academy of Sciences of the United States of America, 1993, Aug-01, Volume: 90, Issue:15

    Topics: Base Sequence; Cells, Cultured; Cockayne Syndrome; DNA Repair; Genes, Bacterial; Humans; In Vitro Techniques; Molecular Sequence Data; Mutagenesis; Plasmids; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1993
Rodent complementation group 8 (ERCC8) corresponds to Cockayne syndrome complementation group A.
    Mutation research, 1996, Feb-15, Volume: 362, Issue:2

    Topics: Animals; Cell Fusion; Cell Line; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; DNA Repair Enzymes; DNA-Binding Proteins; Genetic Complementation Test; Humans; Hybrid Cells; L Cells; Leukemia L5178; Mice; Proteins; Pyrimidine Dimers; Transcription Factors; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1996
The human CSB (ERCC6) gene corrects the transcription-coupled repair defect in the CHO cell mutant UV61.
    Nucleic acids research, 1996, Sep-01, Volume: 24, Issue:17

    Topics: Animals; Cell Survival; Cell-Free System; CHO Cells; Cockayne Syndrome; Cricetinae; DNA Helicases; DNA Polymerase II; DNA Repair; DNA Repair Enzymes; Dose-Response Relationship, Radiation; Genes, myc; Genetic Complementation Test; Humans; Mutation; Poly-ADP-Ribose Binding Proteins; Pyrimidine Dimers; Transcription, Genetic; Transfection; Ultraviolet Rays

1996
Cockayne syndrome group B protein enhances elongation by RNA polymerase II.
    Proceedings of the National Academy of Sciences of the United States of America, 1997, Oct-14, Volume: 94, Issue:21

    Topics: Base Sequence; Cockayne Syndrome; DNA; DNA Helicases; DNA Repair Enzymes; Enzyme Activation; Humans; Poly-ADP-Ribose Binding Proteins; Pyrimidine Dimers; RNA; RNA Polymerase II; Substrate Specificity; Templates, Genetic; Transcription Factors; Transcription Factors, General; Transcription, Genetic; Transcriptional Elongation Factors

1997
A difference in the pattern of repair in a large genomic region in UV-irradiated normal human and Cockayne syndrome cells.
    Mutation research, 1997, Volume: 385, Issue:2

    Topics: Actins; Cell Line; Cockayne Syndrome; DNA; DNA Damage; DNA Probes; DNA Repair; Fibroblasts; Genome; Humans; Insulin; Pyrimidine Dimers; Ultraviolet Rays; X Chromosome; Xeroderma Pigmentosum

1997
Enhanced UV-induced mutagenesis in the UV61 cell line, the Chinese hamster homologue of Cockayne's syndrome B, is associated with defective transcription coupled repair of cyclobutane pyrimidine dimers.
    Mutation research, 1998, Oct-21, Volume: 409, Issue:1

    Topics: Animals; Base Sequence; Cell Survival; CHO Cells; Cockayne Syndrome; Cricetinae; DNA; DNA Repair; Humans; Hypoxanthine Phosphoribosyltransferase; Mutagenesis; Pyrimidine Dimers; Radiation Tolerance; RNA; Transcription, Genetic; Ultraviolet Rays

1998
The relative expression of mutated XPB genes results in xeroderma pigmentosum/Cockayne's syndrome or trichothiodystrophy cellular phenotypes.
    Human molecular genetics, 1999, Volume: 8, Issue:6

    Topics: Cell Line, Transformed; Child; Child, Preschool; Cockayne Syndrome; DNA; DNA Helicases; DNA Repair; DNA-Binding Proteins; DNA, Complementary; Gene Expression Regulation; Hair Diseases; Humans; Male; Middle Aged; Mutation; Pyrimidine Dimers; Recombinant Fusion Proteins; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1999
Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription.
    Nucleic acids research, 1999, Jul-15, Volume: 27, Issue:14

    Topics: Adenosine Deaminase; Cell Survival; Cells, Cultured; Cockayne Syndrome; DNA Damage; DNA Repair; Dose-Response Relationship, Radiation; Fibroblasts; Genetic Complementation Test; Humans; Pyrimidine Dimers; Radiation Tolerance; RNA; Time Factors; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1999
The ATPase domain but not the acidic region of Cockayne syndrome group B gene product is essential for DNA repair.
    Molecular biology of the cell, 1999, Volume: 10, Issue:11

    Topics: 4-Nitroquinoline-1-oxide; Adenosine Triphosphatases; Amino Acid Sequence; Animals; Cell Line; Cell Survival; Clone Cells; Cockayne Syndrome; Cricetinae; DNA Damage; DNA Helicases; DNA Repair; DNA Repair Enzymes; Humans; Molecular Sequence Data; Mutagenesis, Site-Directed; Poly-ADP-Ribose Binding Proteins; Pyrimidine Dimers; RNA, Messenger; Tetrahydrofolate Dehydrogenase; Transfection; Ultraviolet Rays

1999
Evidence for defective repair of cyclobutane pyrimidine dimers with normal repair of other DNA photoproducts in a transcriptionally active gene transfected into Cockayne syndrome cells.
    Mutation research, 1991, Volume: 255, Issue:3

    Topics: Cell Line; Chloramphenicol O-Acetyltransferase; Cockayne Syndrome; Deoxyribodipyrimidine Photo-Lyase; DNA; DNA Repair; Escherichia coli; Genome, Human; Humans; Plasmids; Pyrimidine Dimers; Transcription, Genetic; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1991
The genetic defect in Cockayne syndrome is associated with a defect in repair of UV-induced DNA damage in transcriptionally active DNA.
    Proceedings of the National Academy of Sciences of the United States of America, 1990, Volume: 87, Issue:12

    Topics: Adenosine Deaminase; Cells, Cultured; Cockayne Syndrome; Deoxyribonuclease EcoRI; DNA; DNA Damage; DNA Probes; DNA Repair; Dwarfism; Fibroblasts; Genes; Humans; Kinetics; Pyrimidine Dimers; Restriction Mapping; Skin; Tetrahydrofolate Dehydrogenase; Transcription, Genetic; Ultraviolet Rays

1990
The role of the nuclear matrix in DNA repair.
    Progress in clinical and biological research, 1990, Volume: 340A

    Topics: Adenosine Deaminase; Cells, Cultured; Cockayne Syndrome; DNA; DNA Damage; DNA Repair; Fibroblasts; Genes; Humans; Nuclear Matrix; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1990
Clinical and biochemical studies in three patients with severe early infantile Cockayne syndrome.
    Human genetics, 1989, Volume: 83, Issue:4

    Topics: Cell Survival; Cells, Cultured; Centrifugation; Chloramphenicol O-Acetyltransferase; Chromatin; Cockayne Syndrome; Cyclobutanes; DNA Repair; Dwarfism; Female; Fibroblasts; Gene Expression; Humans; Infant; Infant, Newborn; Male; Pyrimidine Dimers; RNA; Transfection; Ultraviolet Rays

1989
The Fritz-Lipmann lecture. DNA repair in human cells. Biochemistry of the hereditary diseases Fanconi's anaemia and Cockayne syndrome.
    European journal of biochemistry, 1987, Jun-01, Volume: 165, Issue:2

    Topics: Acetyltransferases; Anemia, Aplastic; Chloramphenicol O-Acetyltransferase; Cockayne Syndrome; DNA; DNA Repair; Dwarfism; Fanconi Anemia; Fibroblasts; Humans; NAD; Poly(ADP-ribose) Polymerases; Pyrimidine Dimers; Transcription, Genetic; Ultraviolet Rays; Xeroderma Pigmentosum

1987
Repair of closely opposed cyclobutyl pyrimidine dimers in UV-sensitive human diploid fibroblasts.
    Mutation research, 1986, Volume: 166, Issue:2

    Topics: Cell Line; Cockayne Syndrome; DNA Glycosylases; DNA Repair; Fanconi Anemia; Humans; Keratosis; Kinetics; N-Glycosyl Hydrolases; Pyrimidine Dimers; Ultraviolet Rays; Xeroderma Pigmentosum

1986
Transient expression of a plasmid gene, a tool to study DNA repair in human cells: defect of DNA repair in Cockayne syndrome; one thymine cyclobutane dimer is sufficient to block transcription.
    European journal of cell biology, 1986, Volume: 39, Issue:2

    Topics: Alkylating Agents; Choline O-Acetyltransferase; Chromosomes, Human; Cockayne Syndrome; Cross-Linking Reagents; DNA; DNA Repair; Dwarfism; Fibroblasts; Gene Expression Regulation; Humans; Plasmids; Pyrimidine Dimers; Transcription, Genetic; Transfection; Ultraviolet Rays; Xeroderma Pigmentosum

1986