pyrimidine has been researched along with Experimental Neoplasms in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (73.08) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.85) | 29.6817 |
| 2010's | 4 (15.38) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| An, B; Chen, C; Fan, R; Li, J; Li, X; Song, X; Wei, S; Zhang, Q; Zou, Y | 1 |
| Amano, Y; Echizen, Y; Hirano, M; Hisamichi, H; Iikubo, K; Iwai, Y; Kameda, M; Kawamoto, Y; Kikuchi, S; Kondoh, Y; Kuriwaki, I; Moritomo, H; Nakazawa, T; Noda, A; Tateishi, Y; Terasaka, T; Tomiyama, H | 1 |
| Abouzid, KAM; Esmat, A; Hossam, M; Ismail, NSM; Lasheen, DS; Mansour, AM; Singab, ANB | 1 |
| Cescon, DW; Hansen, MD; Hoj, JP; Siddiqui-Jain, A | 1 |
| Adrian, F; Arrebola, R; Barrague, M; Benhamou, B; Bonnet, L; Bouaboula, M; Cao, H; Castaldi, MP; Cheng, H; Cornella-Taracido, I; Courjaud, A; Gao, Q; Garcia-Echeverria, C; Gee, P; Grepin, C; Harper, D; He, T; Koundinya, M; Licht, S; Lionne, B; Menguy, I; Morris, A; Munson, M; Murtie, J; Newcombe, R; Perrault, C; Pollard, J; Reiling, S; Schreiber, I; Simard, D; Sudhalter, J; Sun, F; Tomlinson, R; Touyer, G; Vougier, S; Wang, Y; Winter, C; Yang, E; Zhang, B | 1 |
| Ding, L; Hu, B; Li, J; Liu, HM; Liu, Y; Ma, LY; Pang, LP; Wang, B; Wang, C; Wang, JJ; Wang, JW; Wang, SQ; Wang, ZJ; Wang, ZR; Zhang, M; Zhang, XD; Zhao, W; Zheng, YC | 1 |
| Cleaver, JE | 1 |
| HANDA, S; HASEGWA, A; HOSHIKAWA, S; KATO, M; MATSUKAWA, T; SASORI, T; TAKAHASHI, K; TATEYAMA, M | 1 |
| ROBINS, RK; SKIPPER, HE; THOMSON, JR | 1 |
| BROCKMAN, RW; CHENG, CC; ROBINS, RK; SCHABEL, FM; SKIPPER, HE; THOMSON, JR | 1 |
| DI MARCO, A | 1 |
| HENDERSON, JF; JUNGA, IG | 2 |
| NISHIMURA, T; TANAKA, N | 1 |
| CARTER, R; HEYN, R; NEWTON, W | 1 |
| MOHLER, WC | 1 |
| ISRAEL, M; MODEST, EJ; PROTOPAPA, HK; SCHLEIN, HN | 2 |
| CAPPUCCINO, JG; GEORGE, M; MERKER, PC; TARNOWSKI, GS | 1 |
| LANGEN, P | 1 |
| BYCHENKOVA, M; POLKINA, R; ZALESSKAYA, L | 1 |
| MORSE, PA; POTTER, VR | 1 |
| GEBERT, R; GENTRY, GA; IVES, DH; MORSE, PA; POTTER, VR | 1 |
| GENTRY, GA; MORSE, PA; POTTER, VR | 1 |
| MANTEGAZZA, P; MIHICH, E; TOMMASINI, R | 1 |
| Fujii, S; Shirasaka, T | 1 |
26 other study(ies) available for pyrimidine and Experimental Neoplasms
| Article | Year |
|---|---|
Design, synthesis and biological evaluation of novel 2,4-diaryl pyrimidine derivatives as selective EGFR
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; ErbB Receptors; Humans; Male; Mice; Mice, Nude; Models, Molecular; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Pyrimidines; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship | 2021 |
Synthesis and structure-activity relationships of pyrimidine derivatives as potent and orally active FGFR3 inhibitors with both increased systemic exposure and enhanced in vitro potency.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Screening Assays, Antitumor; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Molecular Dynamics Simulation; Molecular Structure; Neoplasms, Experimental; NIH 3T3 Cells; Pyrimidines; Receptor, Fibroblast Growth Factor, Type 3; Solubility; Structure-Activity Relationship; Urinary Bladder Neoplasms | 2021 |
Discovery of anilino-furo[2,3-d]pyrimidine derivatives as dual inhibitors of EGFR/HER2 tyrosine kinase and their anticancer activity.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; ErbB Receptors; Female; Humans; Mice; Molecular Structure; Neoplasms, Experimental; Protein Kinase Inhibitors; Pyrimidines; Structure-Activity Relationship; Tumor Cells, Cultured | 2018 |
Pharmacology and in vivo efficacy of pyridine-pyrimidine amides that inhibit microtubule polymerization.
Topics: Amides; Animals; Cell Line, Tumor; Cell Proliferation; Dogs; Dose-Response Relationship, Drug; Humans; Mice; Microsomes, Liver; Microtubules; Molecular Structure; Neoplasms, Experimental; Polymerization; Pyridines; Pyrimidines; Rats; Structure-Activity Relationship | 2018 |
Dependence on the Pyrimidine Biosynthetic Enzyme DHODH Is a Synthetic Lethal Vulnerability in Mutant KRAS-Driven Cancers.
Topics: Animals; Antineoplastic Agents; Cell Proliferation; Dihydroorotate Dehydrogenase; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Female; Humans; Mice; Mice, SCID; Mutation; Neoplasms, Experimental; Oxidoreductases Acting on CH-CH Group Donors; Pancreatic Neoplasms; Proto-Oncogene Proteins p21(ras); Pyrimidines; Small Molecule Libraries; Tumor Cells, Cultured | 2018 |
Design, synthesis, and structure-activity relationship of novel LSD1 inhibitors based on pyrimidine-thiourea hybrids as potent, orally active antitumor agents.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Cell Survival; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Histone Demethylases; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Molecular Structure; Neoplasms, Experimental; Pyrimidines; Structure-Activity Relationship; Thiourea | 2015 |
Photoreactivation.
Topics: Animals; DNA Repair; Enzymes; Genetics; History, 20th Century; Mice; Neoplasms, Experimental; Photochemistry; Pyrimidines | 2003 |
[Effects of several pyrimidine compounds on the ascites tumor cells; preliminary report].
Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Humans; Neoplasms, Experimental; Pyrimidines | 1954 |
Inhibition of experimental neoplasms by 4-aminopyrazolo (3, 4-d) pyrimidine.
Topics: Animals; Humans; Neoplasms, Experimental; Pyrimidines | 1955 |
Structure-activity relationships observed on screening a series of pyrazolopyrimidines against experimental neoplasms.
Topics: Animals; Antineoplastic Agents; Humans; Neoplasms, Experimental; Pyrimidines; Structure-Activity Relationship | 1957 |
Evaluation of antineoplastic activity of pyrimidine analogues by autoradiographic method.
Topics: Animals; Antineoplastic Agents; Autoradiography; Neoplasms, Experimental; Pyrimidines | 1957 |
Inhibition of ascites tumor growth by 4-aminopyrazolo-(3,4-d)pyrimidine in combination with azaserine, 6-mercaptopurine, and thioguanine.
Topics: Animals; Ascites; Azaserine; Azoles; Carcinoma, Ehrlich Tumor; Humans; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Pyrimidines; Serine; Thioguanine | 1960 |
Treatment of ascites tumors with 4-aminopyrazolo (3,4-d)pyrimidine alone and in combination with azaserine, thioguanine, and 6-mercaptopurine.
Topics: Animals; Antineoplastic Agents; Ascites; Azaserine; Carcinoma, Ehrlich Tumor; Humans; Mercaptopurine; Neoplasms, Experimental; Pyrimidines; Thioguanine | 1961 |
BIOLOGICAL STUDIES ON BACIMETHRIN, A PYRIMIDINE ANTIBIOTIC, AND MONAZOMYCIN.
Topics: Animals; Anti-Bacterial Agents; Carcinoma, Ehrlich Tumor; Macrolides; Mice; Neoplasms, Experimental; Newcastle disease virus; Pyrimidines; Research; Salmonella Infections; Salmonella Infections, Animal; Staphylococcal Infections; Tissue Culture Techniques | 1963 |
ELDERFIELD PYRIMIDINE MUSTARD (NSC-23436) IN ACUTE LEUKEMIA IN CHILDREN--A PHASE I STUDY.
Topics: Animals; Bicarbonates; Dogs; Hodgkin Disease; Leukemia; Leukemia L1210; Leukopenia; Mice; Mustard Plant; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Nitrogen Mustard Compounds; Pyrimidines; Research; Sarcoma 180; Toxicology | 1963 |
CYTOTOXICITY OF HYDROXYUREA (NSC-32065) REVERSIBLE BY PYRIMIDINE DEOXYRIBOSIDES IN A MAMMALIAN CELL LINE GROWN IN VITRO.
Topics: Antimetabolites; Cell Line; Cricetinae; Hydroxyurea; In Vitro Techniques; Neoplasms; Neoplasms, Experimental; Nucleosides; Pyrimidine Nucleosides; Pyrimidines; Research; Thymidine; Tissue Culture Techniques; Urea | 1964 |
PYRIMIDINE DERIVATIVES. V. SYNTHESIS OF SUBSTITUTED PYRIMIDINES FROM 4-AMINO-6-CHLORO-2-METHYLTHIOPYRIMIDINE.
Topics: Antineoplastic Agents; Biological Assay; Chemistry, Pharmaceutical; Enterococcus faecalis; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyrimidines; Research; Spectrum Analysis; Tissue Culture Techniques | 1964 |
GROWTH INHIBITION OF CLOSTRIDIUM FESERI BY CARCINOSTATIC PURINE AND PYRIMIDINE ANALOGS. I. EFFECT OF MEDIUM ON GROWTH INHIBITION.
Topics: Adenocarcinoma; Antineoplastic Agents; Clostridium; Culture Media; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; Research; Tissue Culture Techniques | 1964 |
PYRIMIDINE DERIVATIVES. VI. 2,4,5-TRIAMINO-6-CHLORO- AND -6-MERCAPTOPYRIMIDINE AND RELATED COMPOUNDS.
Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Enterococcus faecalis; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyrimidines; Research; Spectrum Analysis | 1964 |
INFLUENCE OF PURINE AND PYRIMIDINE COMPOUNDS ON DNA-SYNTHESIS OF ASCITES-TUMOUR CELLS.
Topics: Animals; Ascites; Carcinoma, Ehrlich Tumor; Cytosine Nucleotides; DNA; DNA, Neoplasm; Fluorouracil; Metabolism; Neoplasms, Experimental; Nucleotides; Pharmacology; Phosphorus Isotopes; Purines; Pyrimidines; Research; Thymine; Uracil; Uracil Nucleotides | 1964 |
RADIOSENSITIZATION OF TUMORS WITH PYRIMIDINE DERIVATIVES.
Topics: Animals; Carcinoma, Ehrlich Tumor; Melanoma; Mice; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyrimidines; Radiation Effects; Research; Skin Neoplasms; Uracil | 1964 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. II. THYMIDINE UPTAKE IN SUSPENSION CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carbon Isotopes; Carcinoma, Hepatocellular; Chromatography; DNA; DNA, Neoplasm; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Neoplasms, Experimental; Pharmacology; Pyrimidines; Radiometry; Rats; Research; Thymidine; Tritium | 1965 |
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. 3. RELATIONSHIP OF THYMIDINE TO THE METABOLISM OF OTHER PYRIMIDINE NUCLEOSIDES IN SUSPENSION CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA.
Topics: Animals; Carcinoma, Hepatocellular; DNA; DNA, Neoplasm; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Neoplasms, Experimental; Nucleosides; Pyrimidine Nucleosides; Pyrimidines; Rats; Research; RNA; RNA, Neoplasm; Thymidine; Tritium | 1965 |
[Activity of various purine and pyrimidine derivatives on the growth of the Walker 256 carcinoma in rats].
Topics: Animals; Carcinoma 256, Walker; Neoplasms, Experimental; Purines; Pyrimidines; Rats | 1951 |
[Regulation of enzyme activities involved in pyrimidine synthesis and its application to cancer chemotherapy].
Topics: Administration, Oral; Animals; Deoxyuridine; Dihydrouracil Dehydrogenase (NAD+); DNA, Neoplasm; Drug Synergism; Fluorouracil; Neoplasms, Experimental; Oxidoreductases; Oxidoreductases Acting on CH-CH Group Donors; Pentosyltransferases; Phosphorylation; Pyrimidines; Sarcoma, Yoshida; Tegafur; Thymidine; Thymine; Uracil; Uridine | 1984 |