Page last updated: 2024-08-21

pyrimidine and Dihydropyrimidine Dehydrogenase Deficiency

pyrimidine has been researched along with Dihydropyrimidine Dehydrogenase Deficiency in 3 studies

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ito, T	1
Meinsma, R; van Gennip, AH; van Kuilenburg, AB	1
Hoffmann, GF; Hofmann, U; Kohlmüller, D; Mürdter, T; Schmidt, C; Schwab, M; Zanger, UM	1

Reviews

2 review(s) available for pyrimidine and Dihydropyrimidine Dehydrogenase Deficiency

Article	Year
Children's toxicology from bench to bed--Liver injury (1): Drug-induced metabolic disturbance--toxicity of 5-FU for pyrimidine metabolic disorders and pivalic acid for carnitine metabolism. The Journal of toxicological sciences, 2009, Volume: 34 Suppl 2 Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carnitine; Cephalosporins; Child; Dihydropyrimidine Dehydrogenase Deficiency; Female; Fluorouracil; Humans; Intestinal Absorption; Pentanoic Acids; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Rats	2009
Pyrimidine degradation defects and severe 5-fluorouracil toxicity. Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9 Topics: Antimetabolites, Antineoplastic; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Exons; Fluorouracil; Genome; Humans; Models, Chemical; Models, Genetic; Pyrimidines	2004

Article

Year

Children's toxicology from bench to bed--Liver injury (1): Drug-induced metabolic disturbance--toxicity of 5-FU for pyrimidine metabolic disorders and pivalic acid for carnitine metabolism.

The Journal of toxicological sciences, 2009, Volume: 34 Suppl 2

Topics: Amidohydrolases; Animals; Anti-Bacterial Agents; Antineoplastic Agents; Carnitine; Cephalosporins; Child; Dihydropyrimidine Dehydrogenase Deficiency; Female; Fluorouracil; Humans; Intestinal Absorption; Pentanoic Acids; Purine-Pyrimidine Metabolism, Inborn Errors; Pyrimidines; Rats

2009

Pyrimidine degradation defects and severe 5-fluorouracil toxicity.

Nucleosides, nucleotides & nucleic acids, 2004, Volume: 23, Issue:8-9

Topics: Antimetabolites, Antineoplastic; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Exons; Fluorouracil; Genome; Humans; Models, Chemical; Models, Genetic; Pyrimidines

2004

Other Studies

1 other study(ies) available for pyrimidine and Dihydropyrimidine Dehydrogenase Deficiency

Article	Year
Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry. Journal of inherited metabolic disease, 2005, Volume: 28, Issue:6 Topics: Adolescent; beta-Alanine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Epilepsy; Exons; Female; Genotype; Humans; Infant; Infant, Newborn; Ions; Male; Mass Spectrometry; Models, Statistical; Mutation; Normal Distribution; Ornithine Carbamoyltransferase Deficiency Disease; Pyrimidines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Thymine; Uracil	2005

Article

Year

Comprehensive analysis of pyrimidine metabolism in 450 children with unspecific neurological symptoms using high-pressure liquid chromatography-electrospray ionization tandem mass spectrometry.

Journal of inherited metabolic disease, 2005, Volume: 28, Issue:6

Topics: Adolescent; beta-Alanine; Child; Child, Preschool; Chromatography, High Pressure Liquid; Dihydropyrimidine Dehydrogenase Deficiency; Dihydrouracil Dehydrogenase (NADP); Epilepsy; Exons; Female; Genotype; Humans; Infant; Infant, Newborn; Ions; Male; Mass Spectrometry; Models, Statistical; Mutation; Normal Distribution; Ornithine Carbamoyltransferase Deficiency Disease; Pyrimidines; Reference Standards; Reproducibility of Results; Sensitivity and Specificity; Spectrometry, Mass, Electrospray Ionization; Thymine; Uracil

2005