pyrimidine has been researched along with Colorectal Neoplasms in 11 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (72.73) | 24.3611 |
| 2020's | 3 (27.27) | 2.80 |
| Authors | Studies |
|---|---|
| Boku, N; Esaki, T; Izawa, N; Kawakami, K; Kawakami, T; Komoda, M; Makiyama, A; Masuishi, T; Mitani, S; Moriwaki, T; Nagashima, K; Nakajima, TE; Okuda, H; Tsuji, Y; Yamamoto, S; Yamamoto, Y; Yamazaki, K | 1 |
| Deng, Z; Jiang, J; Lang, X; Qin, Y; Shu, Y; Wang, G; Wang, J; Xie, K; Xu, H; Zhang, W; Zhang, Y | 1 |
| Athineos, D; Blanco, GR; Blyth, K; Brunton, H; Dhayade, S; Fernandez-de-Cossio-Diaz, J; Lilla, S; Mackay, GM; Meiser, J; Oizel, K; Pietzke, M; Sumpton, D; Tait-Mulder, J; Vazquez, A; Zanivan, SR | 1 |
| Blanco, C; García, MI; García-Alfonso, P; García-González, X; Grávalos, C; Iglesias, I; Longo, F; López-Fernández, LA; Martínez, J; Martínez, V; Pachón, V; Pellicer, M; Robles, L; Rueda, D; Salvador, S; Sanjurjo, M | 1 |
| Aizawa, Y; Akamoto, S; Aoki, M; Enomoto, A; Fujishita, T; Fukuda, S; Haba, R; Hirayama, A; Igarashi, K; Ishikawa, T; Kajino-Sakamoto, R; Kato, K; Kojima, Y; Kushida, Y; Nakagawa, T; Okano, K; Oshima, M; Saitoh, K; Sato, S; Satoh, K; Soga, T; Sugimoto, M; Suzuki, Y; Tabata, S; Taketo, MM; Tomita, M; Yachida, S | 1 |
| Abbosh, PH; Dai, J; El-Deiry, WS; Finnberg, NK; Gokare, P; Murphy, ME | 1 |
| Burge, M; Clarke, S; Cordwell, C; Gibbs, P; Reece, W; Tebbutt, N | 1 |
| Cai, J; Chen, J; Dai, J; Feng, J; Ge, S; Huang, L; Li, M; Liao, X; Ma, H; Qin, K; Wang, Q; Xie, C; Yu, Q; Yuan, X; Zang, A; Zhang, T | 1 |
| Cecchin, E; D'Andrea, M; De Mattia, E; Errante, D; Landini, I; Lonardi, S; Mazzei, T; Mini, E; Nobili, S; Pella, N; Perrone, G; Petreni, P; Polesel, J; Rizzolio, F; Toffoli, G; Zanusso, C | 1 |
| Aparicio, T; Artru, P; Bonnetain, F; Boussaha, T; Cauchin, E; Coriat, R; Des Guetz, G; Ferru, A; Karayan-Tapon, L; Lécaille, C; Lecomte, T; Matysiak-Budnik, T; Michel, P; Mouillet, G; Pagès, JC; Sefrioui, D; Sickersen, G; Silvain, C; Taïeb, J; Tougeron, D; Trouilloud, I; Vernerey, D; Zaanan, A | 1 |
| Bellahcène, A; Bellier, J; Bletard, N; Castronovo, V; Chiavarina, B; Dehon, R; Delvenne, P; Demetter, P; Durieux, F; Goldman, S; Hustinx, R; Lovinfosse, P; Nokin, MJ; Peulen, O; Sherer, F; Turtoi, A; Uchida, K; Verset, L | 1 |
1 review(s) available for pyrimidine and Colorectal Neoplasms
| Article | Year |
|---|---|
Prognostic and predictive role of DNA mismatch repair status in stage II-III colorectal cancer: A systematic review and meta-analysis.
Topics: Colorectal Neoplasms; Disease-Free Survival; DNA Mismatch Repair; Humans; Neoplasm Staging; Prognosis; Pyrimidines | 2020 |
2 trial(s) available for pyrimidine and Colorectal Neoplasms
| Article | Year |
|---|---|
An Australian translational study to evaluate the prognostic role of inflammatory markers in patients with metastatic ColorEctal caNcer Treated with bevacizumab (Avastin™) [ASCENT].
Topics: Adult; Angiogenesis Inhibitors; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Biomarkers, Tumor; Camptothecin; Capecitabine; Colorectal Neoplasms; Deoxycytidine; Disease Progression; Female; Fluorouracil; Humans; Inflammation; Leucovorin; Lymphocytes; Male; Neutrophils; Organoplatinum Compounds; Oxaliplatin; Oxaloacetates; Prognosis; Proportional Hazards Models; Prospective Studies; Pyrimidines; Reproducibility of Results | 2013 |
SLCO1B1 and SLC19A1 gene variants and irinotecan-induced rapid response and survival: a prospective multicenter pharmacogenetics study of metastatic colorectal cancer.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Colorectal Neoplasms; Female; Haplotypes; Humans; Irinotecan; Linkage Disequilibrium; Liver-Specific Organic Anion Transporter 1; Male; Middle Aged; Neoplasm Metastasis; Organic Anion Transporters; Pharmacogenetics; Polymorphism, Single Nucleotide; Prospective Studies; Pyrimidines; Reduced Folate Carrier Protein; Survival Analysis; Time Factors; Treatment Outcome; Young Adult | 2013 |
8 other study(ies) available for pyrimidine and Colorectal Neoplasms
| Article | Year |
|---|---|
Second-line chemotherapy after early disease progression during first-line chemotherapy containing bevacizumab for patients with metastatic colorectal cancer.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Angiogenesis Inhibitors; Antineoplastic Agents, Immunological; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Camptothecin; Colorectal Neoplasms; Disease Progression; Drug Administration Schedule; Female; Fluorouracil; Humans; Irinotecan; Japan; Leucovorin; Male; Middle Aged; Organoplatinum Compounds; Oxaliplatin; Progression-Free Survival; Pyrimidines; Retrospective Studies; Time Factors | 2021 |
Formate induces a metabolic switch in nucleotide and energy metabolism.
Topics: Adenosine Triphosphate; Adenylate Kinase; Aminoimidazole Carboxamide; Animals; Cell Line, Tumor; Colorectal Neoplasms; Disease Models, Animal; Energy Metabolism; Female; Formates; Humans; Mice, Inbred C57BL; Models, Biological; Models, Genetic; Nucleotides; Orotic Acid; Pyrimidines; Ribonucleotides | 2020 |
Use of exome sequencing to determine the full profile of genetic variants in the fluoropyrimidine pathway in colorectal cancer patients affected by severe toxicity.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Biomarkers; Capecitabine; Colorectal Neoplasms; Drug-Related Side Effects and Adverse Reactions; Exome; Female; Genotype; Humans; Male; Middle Aged; Polymorphism, Single Nucleotide; Pyrimidines | 2017 |
Global metabolic reprogramming of colorectal cancer occurs at adenoma stage and is induced by MYC.
Topics: Adenoma; Animals; Carcinogenesis; Cell Proliferation; Colorectal Neoplasms; Disease Models, Animal; Female; Genes, myc; Humans; Male; Metabolomics; Mice; Proto-Oncogene Proteins c-myc; Pyrimidines; Transcriptome | 2017 |
P53 represses pyrimidine catabolic gene dihydropyrimidine dehydrogenase (DPYD) expression in response to thymidylate synthase (TS) targeting.
Topics: Animals; Cell Line, Tumor; Cell Survival; Chromatography, Liquid; Colorectal Neoplasms; Dihydrouracil Dehydrogenase (NADP); Disease Models, Animal; DNA-Activated Protein Kinase; DNA-Binding Proteins; Gene Expression Regulation, Enzymologic; Humans; Male; Mice; Mice, Knockout; Models, Biological; Nuclear Proteins; Polymorphism, Genetic; Protein Binding; Pyrimidines; Signal Transduction; Tandem Mass Spectrometry; Thymidylate Synthase; Tumor Suppressor Protein p53 | 2017 |
MTHFR-1298 A>C (rs1801131) is a predictor of survival in two cohorts of stage II/III colorectal cancer patients treated with adjuvant fluoropyrimidine chemotherapy with or without oxaliplatin.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chemotherapy, Adjuvant; Colorectal Neoplasms; Disease-Free Survival; Female; Genotype; Humans; Male; Methylenetetrahydrofolate Reductase (NADPH2); Middle Aged; Neoplasm Staging; Organoplatinum Compounds; Oxaliplatin; Polymorphism, Single Nucleotide; Prognosis; Pyrimidines; Young Adult | 2015 |
Efficacy of Adjuvant Chemotherapy in Colon Cancer With Microsatellite Instability: A Large Multicenter AGEO Study.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Brain Neoplasms; Chemotherapy, Adjuvant; Colonic Neoplasms; Colorectal Neoplasms; Female; Germ-Line Mutation; Humans; Kaplan-Meier Estimate; Male; Microsatellite Instability; Middle Aged; Neoplasm Staging; Neoplastic Syndromes, Hereditary; Organoplatinum Compounds; Oxaliplatin; Pyrimidines; Retrospective Studies; Treatment Outcome | 2016 |
Methylglyoxal-Mediated Stress Correlates with High Metabolic Activity and Promotes Tumor Growth in Colorectal Cancer.
Topics: Adult; Aged; Animals; Carnosine; Cell Line, Tumor; Cell Proliferation; Chickens; Cohort Studies; Colorectal Neoplasms; Fluorodeoxyglucose F18; Glycolysis; Humans; Lactoylglutathione Lyase; Middle Aged; Neoplasm Staging; Positron-Emission Tomography; Pyrimidines; Pyruvaldehyde; Stress, Physiological | 2017 |