Page last updated: 2024-08-21

pyrimidine and Benign Neoplasms

pyrimidine has been researched along with Benign Neoplasms in 67 studies

Research

Studies (67)

Timeframe	Studies, this research(%)	All Research%
pre-1990	28 (41.79)	18.7374
1990's	1 (1.49)	18.2507
2000's	10 (14.93)	29.6817
2010's	20 (29.85)	24.3611
2020's	8 (11.94)	2.80

Authors

Authors	Studies
Bhandare, RR; Bloukh, SH; Edis, Z; Jadhav, M; Khan, TA; Sankhe, K	1
Herr, P; Walter, M	1
Cortés-Percino, A; Merino-Montiel, P; Meza-Reyes, S; Montiel-Smith, S; Padrón, JM; Puerta, A; Romero-López, A; Vega-Báez, JL	1
Ceppi, P; Siddiqui, A	1
Hertz, DL; Sahai, V	1
Kumar, N; Mishra, I; Mishra, R; Sachan, N	1
Chen, XB; Wang, S; Wang, SQ; Yu, B; Yuan, XH; Zhao, W	1
Ayati, A; Foroumadi, A; Moghimi, S; Toolabi, M	1
Anant, A; Asati, V; Gupta, GD; Kaur, K; Patel, P	1
Cai, Z; He, R; Huang, W; Liu, S; Lv, X; Pan, J; Pan, X; Shao, Y; Sun, J; Xi, J; Zhang, J; Zhao, Y; Zhuang, R	1
Baus, D; Berdis, AJ; Hernandez-Sanchez, W; Taylor, DJ; Whited, TL; Xu, M; Zeng, X; Zhang, J	1
Adler, L; Admon, A; Agemy, L; Auslander, N; Barnea, E; Brandis, A; Carmel, N; Carracedo, A; Dimmock, D; Eilam, R; Elhasid, R; Erez, A; Hannenhalli, S; Helbling, D; Itkin, M; Kalaora, S; Karathia, H; Keshet, R; Lee, JS; Levy, R; Malitsky, S; Nagamani, SCS; Pinto, S; Rabinovich, S; Ruppin, E; Samuels, Y; Scherz, A; Silberman, A; Stern-Ginossar, N; Stettner, N; Sun, Q; Unda, M; Weiss, H; Wilson, DM	1
Seton-Rogers, S	1
Bankhead, A; Cuthbertson, CR; Madak, JT; Neamati, N; Showalter, HD	1
An, YJ; Bajzikova, M; Berridge, MV; Bezawork-Geleta, A; Boukalova, S; Chatre, L; Coelho, AR; Cunha-Oliveira, T; Davidova, E; Dong, L; Dvorakova-Hortova, K; Endaya, B; Ezrova, Z; Gurlich, R; Hozak, P; Hubackova, S; Huynh, T; Judasova, K; Kluckova, K; Kolar, F; Koopman, WJH; Kovarova, J; Krobova, L; Kubista, M; Magalhaes Novais, S; Maghzal, GJ; Nahacka, Z; Neuzil, J; Novakova, A; Oh, S; Oliveira, PJ; Olsinova, M; Pacak, K; Park, S; Ricchetti, M; Rohlena, J; Rohlenova, K; Sandoval-Acuña, C; Sardao, VA; Serafim, TL; Sobol, M; Stocker, R; Strnad, H; Svec, D; Truksa, J; Vanova, K; Zhang, T; Zhou, Y; Zobalova, R	1
Abe, Y; Caaveiro, JMM; Fuchida, H; Hamachi, I; Hatsuyama, Y; Koyanagi, S; Kuwata, K; Matsunaga, N; Miura, C; Morimoto, S; Nakao, T; Ohdo, S; Ojida, A; Okamoto, K; Ono, M; Sakamoto, S; Sato, M; Shibata, T; Shindo, N; Shiroishi, M; Tamura, T; Tokunaga, K; Ueda, T; Watari, K; Yamaguchi, Y	1
Banzi, M; Bonelli, C; Casali, B; Damato, A; Farnetti, E; Iachetta, F; Nicoli, D; Pinto, C; Romagnani, A; Tofani, L; Zamponi, R	1
Cheng, L; Li, K; Li, S; Li, X; Ma, L; Ma, Q	1
Dong, S; Kuo, MS; Nikolayev, A; Tolstikov, V; Zhao, G	1
Bair, KW; Baumeister, T; Buckmelter, AJ; Cheng, E; Clodfelter, KH; Crocker, L; Dragovich, PS; Fu, B; Han, B; Ho, YC; Li, G; Liederer, BM; Lin, J; Liu, X; Ly, J; O'Brien, T; Reynolds, DJ; Sampath, D; Skelton, N; Smith, CC; Tay, S; Wang, W; Wang, Z; Xiao, Y; Yuen, PW; Zak, M; Zhang, L; Zhao, G; Zheng, X	1
Liu, HM; Ma, LY; Pang, LP; Shao, KP; Wang, B; Wang, SQ; Xue, DQ; Zhang, M; Zheng, YC	1
Asao, T; Kaira, K	1
Arnould, S; Baraibar, M; Caramel, J; Delpech, H; Dubois, E; Friguet, B; Hatchi, E; Houlès, T; Julien, E; Kirsh, O; Lacroix, M; Le Cam, L; Rodier, G; Sardet, C; Severac, D	1
Adler, L; Agron, S; Brandis, A; Dimmock, D; Erez, A; Helbling, D; Itzkovitz, S; Korman, S; Nagamani, SC; Rabinovich, S; Ruppin, E; Sarver, A; Silberman, A; Stettner, N; Sun, Q; Ulitsky, I; Yizhak, K	1
Asara, JM; Cantley, LC; Mathur, D; Murty, VV; Ozturk, S; Parsons, R; Pegno, S; Schoenfeld, S; Steinbach, N; Stratikopoulos, E; Yong, R	1
Ciudad, CJ; Félix, AJ; Noé, V; Rodríguez, L; Villalobos, X	1
Bamaung, NY; Bell, RL; Bouska, J; Davidsen, SK; Erickson, SA; Fidanze, SD; Hu, X; Hubbard, RD; Johnson, EF; Kovar, P; Osterling, DJ; Palazzo, F; Sheppard, GS; Tucker, LA; Wang, J; Wilsbacher, JL; Zhang, Q	1
Cai, S; Dobrenkov, K; Hricak, H; Likar, Y; Olszewska, M; Ponomarev, V; Shenker, L	1
Balzarini, J; Bronckaers, A; Liekens, S	1
Batzler, A; Fridley, BL; Jenkins, GD; Ji, Y; Li, F; Li, L; Matimba, A; Wang, L; Weinshilboum, RM	1
Brown, B; Chan, X; Chung, TD; Dahl, R; Diaz, P; Godoi, P; Hurder, A; Jin, C; Rascon, J; Reed, JC; Sergienko, E; Su, Y; Zhai, D	1
WOODHOUSE, DL	1
EBNER, H; SCHNEIDER, W	1
ROGERS, S	1
PREZIOSI, P	1
HENDERSON, JF; JUNGA, IG	3
BLAIR, DG; MORRIS, HP; ONO, T; POTTER, VR	1
GREKH, IF; KARLINSKAIA, RS; TURBINA, IL	4
BYCHENKOVA, MN; POLKINA, RI; ZALESSKAIA, LI	1
CARTER, R; HEYN, R; NEWTON, W	1
MOHLER, WC	1
AKSAMITNAIA, Ia	1
ISRAEL, M; MODEST, EJ; PROTOPAPA, HK; SCHLEIN, HN	2
BOLTON, CF; MOERTEL, CG; REITEMEIER, RJ; SHORTER, RG	1
CAPPUCCINO, JG; GEORGE, M; MERKER, PC; TARNOWSKI, GS	1
ITZHAKI, S	1
AMIEL, JL; CATTAN, A; MATHE, G; SCHLUMBERGER, JR; SCHNEIDER, M; SCHWARZENBERG, L	1
BYCHENKOVA, M; POLKINA, R; ZALESSKAYA, L	1
MORSE, PA; POTTER, VR	1
HANDSCHUMACHER, RE; PASTERNAK, CA	1
CARPENDER, JW; LANIER, RR	1
BARKER, GR; DHAR, MM; PARSONS, LD	1
ENGELMAN, M; GELLHORN, A	1
Paul, K; Singh, P	1
Kaur, P; Kaur, S; Kumar, S; Luxami, V; Singh, P	1
Beaudoin, B; Bray, K; Chen, G; Degenhardt, K; Jin, S; Karp, CM; Kongara, S; Mathew, R; White, E	1
Kitayama, J; Kobunai, T; Nagawa, H; Sasaki, S	1
Dick, CL; Lindsey, JS; Petty, AP	1
Ketterling, RP; Sommer, SS	1
Rew, DA; Wilson, GD	1
Kuhara, T; Ohdoi, C; Ohse, M	1

Reviews

12 review(s) available for pyrimidine and Benign Neoplasms

Article	Year
Synthetic Strategies of Pyrimidine-Based Scaffolds as Aurora Kinase and Polo-like Kinase Inhibitors. Molecules (Basel, Switzerland), 2021, Aug-26, Volume: 26, Issue:17 Topics: Animals; Antineoplastic Agents; Aurora Kinases; Cell Cycle; Cell Cycle Proteins; Drug Discovery; Humans; Neoplasms; Polo-Like Kinase 1; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; Pyrimidines	2021
Re-Discovery of Pyrimidine Salvage as Target in Cancer Therapy. Cells, 2022, 02-20, Volume: 11, Issue:4 Topics: Neoplasms; Nucleosides; Nucleotides; Pyrimidines	2022
A non-proliferative role of pyrimidine metabolism in cancer. Molecular metabolism, 2020, Volume: 35 Topics: Animals; Cell Differentiation; Cell Proliferation; Disease Progression; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Metastasis; Neoplasms; Neoplastic Stem Cells; Pyrimidines	2020
A Review on Anticancer Activities of Thiophene and Its Analogs. Mini reviews in medicinal chemistry, 2020, Volume: 20, Issue:19 Topics: Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Pyrimidines; Structure-Activity Relationship; Thiophenes	2020
FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application. European journal of medicinal chemistry, 2021, Mar-15, Volume: 214 Topics: Antineoplastic Agents; Bridged Bicyclo Compounds, Heterocyclic; Humans; Molecular Structure; Neoplasms; Pyrimidines; United States; United States Food and Drug Administration	2021
Pyrimidine-based EGFR TK inhibitors in targeted cancer therapy. European journal of medicinal chemistry, 2021, Oct-05, Volume: 221 Topics: Antineoplastic Agents; ErbB Receptors; Humans; Molecular Structure; Neoplasms; Protein Kinase Inhibitors; Pyrimidines	2021
Pyrazolopyrimidines as anticancer agents: A review on structural and target-based approaches. European journal of medicinal chemistry, 2021, Dec-05, Volume: 225 Topics: Antineoplastic Agents; Cell Proliferation; Humans; Molecular Structure; Neoplasms; Pyrazoles; Pyrimidines	2021
Changing mutational patterns. Nature reviews. Cancer, 2018, Volume: 18, Issue:10 Topics: Animals; Carbon-Nitrogen Ligases; Humans; Mice; Mutation; Neoplasms; Pyrimidines; Urea	2018
Revisiting the role of dihydroorotate dehydrogenase as a therapeutic target for cancer. Pharmacology & therapeutics, 2019, Volume: 195 Topics: Animals; Cell Differentiation; Dihydroorotate Dehydrogenase; Humans; Molecular Targeted Therapy; Neoplasms; Oxidoreductases Acting on CH-CH Group Donors; Pyrimidines	2019
Polypurine Reverse Hoogsteen Hairpins as a Gene Silencing Tool for Cancer. Current medicinal chemistry, 2017, Volume: 24, Issue:26 Topics: Animals; Drug Resistance, Neoplasm; Gene Silencing; Humans; Neoplasms; Pyrimidines	2017
The factor IX gene as a model for analysis of human germline mutations: an update. Human molecular genetics, 1996, Volume: 5 Spec No Topics: Age Factors; Base Sequence; Factor IX; Founder Effect; Germ-Line Mutation; Hemophilia B; Humans; Molecular Sequence Data; Mosaicism; Mutagenesis; Neoplasms; Nucleic Acid Conformation; Purines; Pyrimidines; Sex Ratio	1996
Cell production rates in human tissues and tumours and their significance. Part II: clinical data. European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology, 2000, Volume: 26, Issue:4 Topics: Adenocarcinoma; Breast Neoplasms; Carcinoma, Squamous Cell; Cell Division; Central Nervous System Neoplasms; DNA; Esophageal Neoplasms; Female; Flow Cytometry; Gastrointestinal Neoplasms; Genital Neoplasms, Female; Head and Neck Neoplasms; Hematologic Neoplasms; Humans; Lasers; Lung Neoplasms; Melanoma; Neoplasms; Prognosis; Pyrimidines; S Phase; Time Factors	2000

Other Studies

55 other study(ies) available for pyrimidine and Benign Neoplasms

Article	Year
Synthesis and Evaluation of Pyrimidine Steroids as Antiproliferative Agents. Molecules (Basel, Switzerland), 2019, Oct-12, Volume: 24, Issue:20 Topics: Acetates; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Neoplasms; Nitrogen; Pregnenolone; Pyrimidines; Steroids; Structure-Activity Relationship	2019
Including DPYD on Cancer Genetic Panels to Prevent Fatal Fluoropyrimidine Toxicity. Journal of the National Comprehensive Cancer Network : JNCCN, 2020, Volume: 18, Issue:4 Topics: Antineoplastic Combined Chemotherapy Protocols; Biomarkers; Drug-Related Side Effects and Adverse Reactions; Genetic Testing; Humans; Mutation; Neoplasms; Pharmacogenomic Variants; Polymorphism, Single Nucleotide; Prognosis; Pyrimidines; Treatment Outcome	2020
Synthesis and evaluation of a series of pyridine and pyrimidine derivatives as type II c-Met inhibitors. Bioorganic & medicinal chemistry, 2017, 06-15, Volume: 25, Issue:12 Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Design; Drug Screening Assays, Antitumor; Humans; Molecular Docking Simulation; Neoplasms; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-met; Pyridines; Pyrimidines	2017
Administration of a Nucleoside Analog Promotes Cancer Cell Death in a Telomerase-Dependent Manner. Cell reports, 2018, 06-05, Volume: 23, Issue:10 Topics: Aminopeptidases; Cell Death; Cell Line, Tumor; Deoxyuridine; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases; DNA; DNA Damage; Gene Silencing; HEK293 Cells; Humans; Models, Biological; Neoplasms; Nuclear Proteins; Nucleosides; Protein Binding; Pyrimidines; RNA, Small Interfering; Serine Proteases; Shelterin Complex; Telomerase; Telomere; Telomere-Binding Proteins; Thymidine; Tripeptidyl-Peptidase 1	2018
Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures. Cell, 2018, 09-06, Volume: 174, Issue:6 Topics: Amino Acid Transport Systems, Basic; Animals; Aspartate Carbamoyltransferase; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line, Tumor; Dihydroorotase; Female; Genomics; Humans; Metabolomics; Mice; Mice, Inbred C57BL; Mice, SCID; Mitochondrial Membrane Transport Proteins; Neoplasms; Ornithine Carbamoyltransferase; Phosphorylation; Pyrimidines; RNA Interference; RNA, Small Interfering; Sirolimus; TOR Serine-Threonine Kinases; Urea	2018
Reactivation of Dihydroorotate Dehydrogenase-Driven Pyrimidine Biosynthesis Restores Tumor Growth of Respiration-Deficient Cancer Cells. Cell metabolism, 2019, 02-05, Volume: 29, Issue:2 Topics: Animals; Cell Line, Tumor; Cell Respiration; Dihydroorotate Dehydrogenase; DNA, Mitochondrial; Humans; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Mitochondria; Neoplasms; Oxidative Phosphorylation; Oxidoreductases Acting on CH-CH Group Donors; Pyrimidines; Ubiquinone	2019
Selective and reversible modification of kinase cysteines with chlorofluoroacetamides. Nature chemical biology, 2019, Volume: 15, Issue:3 Topics: Acetamides; Animals; Antineoplastic Agents; Cell Line; Cysteine; ErbB Receptors; Humans; Mice; Mice, Nude; Neoplasms; Phosphotransferases; Protein Kinase Inhibitors; Pyrimidines; Quinazolines; Structure-Activity Relationship; Xenograft Model Antitumor Assays	2019
The clinical relevance of multiple DPYD polymorphisms on patients candidate for fluoropyrimidine based-chemotherapy. An Italian case-control study. British journal of cancer, 2019, Volume: 120, Issue:8 Topics: Adult; Aged; Aged, 80 and over; Cohort Studies; Dihydrouracil Dehydrogenase (NADP); Female; Humans; Male; Middle Aged; Neoplasms; Pharmacogenetics; Polymorphism, Single Nucleotide; Pyrimidines	2019
Transcriptomic analysis of differentially expressed genes in the Ras1(CA)-overexpressed and wildtype posterior silk glands. BMC genomics, 2014, Mar-09, Volume: 15 Topics: Animals; Animals, Genetically Modified; Bombyx; Cell Cycle; Computational Biology; Gene Expression Profiling; Gene Expression Regulation; High-Throughput Nucleotide Sequencing; Insulin; MAP Kinase Signaling System; Mechanistic Target of Rapamycin Complex 1; Molecular Sequence Annotation; Multiprotein Complexes; Neoplasms; Phosphatidylinositol 3-Kinases; Purines; Pyrimidines; raf Kinases; ras Proteins; Reproducibility of Results; Sequence Analysis, RNA; Signal Transduction; TOR Serine-Threonine Kinases; Transcriptome	2014
Metabolomics analysis of metabolic effects of nicotinamide phosphoribosyltransferase (NAMPT) inhibition on human cancer cells. PloS one, 2014, Volume: 9, Issue:12 Topics: Amino Acids; Cell Line, Tumor; Citric Acid Cycle; Cluster Analysis; Creatine; Glycolysis; Humans; Lipid Metabolism; Mass Spectrometry; Metabolic Networks and Pathways; Metabolome; Metabolomics; Neoplasms; Nicotinamide Phosphoribosyltransferase; Pentose Phosphate Pathway; Purines; Pyrimidines	2014
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubility. Bioorganic & medicinal chemistry letters, 2015, Feb-01, Volume: 25, Issue:3 Topics: Animals; Binding Sites; Cell Line, Tumor; Cell Membrane Permeability; Cell Proliferation; Crystallography, X-Ray; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Dogs; Enzyme Inhibitors; Female; Half-Life; Humans; Kinetics; Madin Darby Canine Kidney Cells; Mice; Mice, Nude; Molecular Dynamics Simulation; Neoplasms; Nicotinamide Phosphoribosyltransferase; Protein Binding; Protein Structure, Tertiary; Pyrimidines; Solubility; Structure-Activity Relationship; Thermodynamics; Transplantation, Heterologous; Water	2015
Design and synthesis of novel 1,2,3-triazole-pyrimidine-urea hybrids as potential anticancer agents. Bioorganic & medicinal chemistry letters, 2015, Mar-01, Volume: 25, Issue:5 Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Drug Design; Drug Screening Assays, Antitumor; Humans; Neoplasms; Pyrimidines; Structure-Activity Relationship; Triazoles; Urea	2015
[Adverse effects of antimetabolite fluoropyrimidine analog]. Nihon rinsho. Japanese journal of clinical medicine, 2015, Volume: 73 Suppl 2 Topics: Antimetabolites, Antineoplastic; Biochemical Phenomena; Drug Tolerance; Fluorine Compounds; Humans; Neoplasms; Pyrimidines	2015
The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions. Cell reports, 2015, Apr-14, Volume: 11, Issue:2 Topics: Animals; Cell Survival; Checkpoint Kinase 1; DNA Damage; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Humans; Mice; Mitochondria; Mouse Embryonic Stem Cells; Neoplasms; Protein Kinases; Pyrimidines; Repressor Proteins; Stress, Physiological; Transcription Factors; Tumor Suppressor Protein p53; Ubiquitin-Protein Ligases	2015
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. Nature, 2015, Nov-19, Volume: 527, Issue:7578 Topics: Animals; Argininosuccinate Synthase; Aspartate Carbamoyltransferase; Aspartic Acid; Calcium-Binding Proteins; Carbamoyl-Phosphate Synthase (Glutamine-Hydrolyzing); Cell Line, Tumor; Cell Proliferation; Citrullinemia; Cytosol; Dihydroorotase; Down-Regulation; Enzyme Activation; Humans; Male; Mice; Mice, SCID; Neoplasms; Organic Anion Transporters; Phosphorylation; Pyrimidines; TOR Serine-Threonine Kinases	2015
PTEN Regulates Glutamine Flux to Pyrimidine Synthesis and Sensitivity to Dihydroorotate Dehydrogenase Inhibition. Cancer discovery, 2017, Volume: 7, Issue:4 Topics: Animals; Ataxia Telangiectasia Mutated Proteins; Dihydroorotate Dehydrogenase; DNA Damage; DNA Replication; Enzyme Inhibitors; Fibroblasts; Gene Knockout Techniques; Glutamine; Humans; Metabolic Networks and Pathways; Mice; Neoplasms; Oxidoreductases Acting on CH-CH Group Donors; PTEN Phosphohydrolase; Pyrimidines	2017
Development of multitargeted inhibitors of both the insulin-like growth factor receptor (IGF-IR) and members of the epidermal growth factor family of receptor tyrosine kinases. Bioorganic & medicinal chemistry letters, 2009, Mar-15, Volume: 19, Issue:6 Topics: Antineoplastic Agents; Cell Line, Tumor; Chemistry, Pharmaceutical; Dimerization; Drug Design; ErbB Receptors; Humans; Lung; Models, Chemical; Neoplasms; Phosphorylation; Pyrimidines; Receptor Protein-Tyrosine Kinases; Receptors, Somatomedin; Signal Transduction	2009
PET imaging of HSV1-tk mutants with acquired specificity toward pyrimidine- and acycloguanosine-based radiotracers. European journal of nuclear medicine and molecular imaging, 2009, Volume: 36, Issue:8 Topics: Acyclovir; Amino Acid Substitution; Animals; Cell Line, Tumor; Drug Resistance, Viral; Gene Expression Regulation, Neoplastic; Genes, Reporter; Herpesvirus 1, Human; Humans; Mice; Mutation; Neoplasms; Phosphorylation; Positron-Emission Tomography; Pyrimidines; Radioactive Tracers; Substrate Specificity; Thymidine Kinase	2009
Improvement of purine and pyrimidine antimetabolite-based anticancer treatment by selective suppression of mycoplasma-encoded catabolic enzymes. The Lancet. Oncology, 2009, Volume: 10, Issue:6 Topics: Antimetabolites, Antineoplastic; Drug Therapy; Humans; Models, Biological; Molecular Sequence Data; Mycoplasma; Mycoplasma Infections; Neoplasms; Pharmaceutical Preparations; Purines; Pyrimidines	2009
Gene set analysis of purine and pyrimidine antimetabolites cancer therapies. Pharmacogenetics and genomics, 2011, Volume: 21, Issue:11 Topics: Antimetabolites; Antineoplastic Agents; Area Under Curve; Cell Line, Tumor; Deoxycytidine; Gemcitabine; Genes, Neoplasm; Humans; Neoplasms; Phenotype; Purines; Pyrimidines; Reproducibility of Results; Thioguanine	2011
High-throughput fluorescence polarization assay for chemical library screening against anti-apoptotic Bcl-2 family member Bfl-1. Journal of biomolecular screening, 2012, Volume: 17, Issue:3 Topics: Drug Evaluation, Preclinical; Fluorescence; Fluorescence Polarization; Fluorescence Resonance Energy Transfer; HeLa Cells; High-Throughput Screening Assays; Humans; Maleimides; Minor Histocompatibility Antigens; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Small Molecule Libraries	2012
The purine and pyrimidine composition of some deoxyribonucleic acids from tumours. The Biochemical journal, 1954, Volume: 56, Issue:2 Topics: DNA; Neoplasms; Nucleic Acids; Purines; Pyrimidines	1954
[Purine and pyrimidine bases of desoxyribonucleic acids in Ehrlich ascites carcinoma in mouse]. Experientia, 1955, Dec-15, Volume: 11, Issue:12 Topics: Animals; Ascites; DNA; Kidney; Liver; Mice; Neoplasms; Nucleic Acids; Purines; Pyrimidines	1955
Studies of the mechanism of action of urethane in initiating pulmonary adenomas in mice. II. Its relation to nucleic acid synthesis. The Journal of experimental medicine, 1957, Apr-01, Volume: 105, Issue:4 Topics: Adenine; Adenoma; Animals; DNA; Lung Neoplasms; Mice; Neoplasms; Nucleic Acids; Orotic Acid; Pyrimidines; RNA; Thymine; Urethane	1957
[Possibility of chemotherapy for neoplasms with pyrimidine & purine antagonists]. La Riforma medica, 1957, Dec-07, Volume: 71, Issue:49 Topics: Antimetabolites; Humans; Neoplasms; Purines; Pyrimidines	1957
Effects of 4-aminopyrazolo (3,4-d)pyrimidine and 1-methyl-4-aminopyrazolo(3,4-d)pyrimidine on nucleic acid purine metabolism in ascites tumors. Cancer research, 1961, Volume: 21 Topics: Adenine; Ascites; Neoplasms; Nucleic Acids; Purines; Pyrimidines	1961
Inhibition of ascites tumor growth by 4-aminopyrazolo-(3,4-d)pyrimidine in combination with azaserine, 6-mercaptopurine, and thioguanine. Cancer research, 1960, Volume: 20 Topics: Animals; Ascites; Azaserine; Azoles; Carcinoma, Ehrlich Tumor; Humans; Mercaptopurine; Neoplasms; Neoplasms, Experimental; Pyrimidines; Serine; Thioguanine	1960
The metabolism of 4-aminopyrazolo(3,4-d)pyrimidine in normal and neoplastic tissues. Cancer research, 1961, Volume: 21 Topics: Adenine; Neoplasms; Pyrimidines	1961
The comparative enzymology and cell origin of rat hepatomas. IV. Pyrimidine metabolism in minimal-deviation tumors. Cancer research, 1963, Volume: 23 Topics: Animals; Carboxy-Lyases; Carcinoma, Hepatocellular; Ligases; Liver Neoplasms; Neoplasms; Oxidoreductases; Pyrimidines; Rats; Transferases	1963
[EFFECT OF SOME PYRIMIDINE DERIVATIVES ON THE METASTASIS OF INOCULATED SSK SARCOMA IN RATS]. Voprosy onkologii, 1963, Volume: 9 Topics: Neoplasm Metastasis; Neoplasms; Pharmacology; Pyrimidines; Rats; Research; Sarcoma; Sarcoma, Experimental	1963
[RADIOSENSITIZATION OF INOCULATED TUMORS WITH SOME PYRIMIDINE DERIVATIVES]. Voprosy onkologii, 1963, Volume: 9 Topics: Animals; Carcinoma, Ehrlich Tumor; Melanoma; Mice; Neoplasms; Pyrimidines; Research; Sarcoma 180	1963
ELDERFIELD PYRIMIDINE MUSTARD (NSC-23436) IN ACUTE LEUKEMIA IN CHILDREN--A PHASE I STUDY. Cancer chemotherapy reports, 1963, Volume: 33 Topics: Animals; Bicarbonates; Dogs; Hodgkin Disease; Leukemia; Leukemia L1210; Leukopenia; Mice; Mustard Plant; Neoplasms; Neoplasms, Experimental; Neuroblastoma; Nitrogen Mustard Compounds; Pyrimidines; Research; Sarcoma 180; Toxicology	1963
[EFFECT OF SOME PYRIMIDINE DERIVATIVES ON THE TOXIC AND ANTINEOPLASTIC ACTION OF SARCOLYSINE]. Voprosy onkologii, 1963, Volume: 9 Topics: Antineoplastic Agents; Cytosine; Erythrocyte Count; Leukocyte Count; Melphalan; Neoplasm Metastasis; Neoplasms; Pyrimidines; Rats; Research; Sarcoma; Sarcoma, Experimental; Toxicology	1963
CYTOTOXICITY OF HYDROXYUREA (NSC-32065) REVERSIBLE BY PYRIMIDINE DEOXYRIBOSIDES IN A MAMMALIAN CELL LINE GROWN IN VITRO. Cancer chemotherapy reports, 1964, Volume: 34 Topics: Antimetabolites; Cell Line; Cricetinae; Hydroxyurea; In Vitro Techniques; Neoplasms; Neoplasms, Experimental; Nucleosides; Pyrimidine Nucleosides; Pyrimidines; Research; Thymidine; Tissue Culture Techniques; Urea	1964
[EFFECT OF SOME PYRIMIDINE DERIVATIVES ON THE GROWTH OF CROCKER'S SARCOMA]. Voprosy onkologii, 1963, Volume: 9 Topics: Animals; Antineoplastic Agents; Cytosine; Mice; Neoplasms; Pharmacology; Pyrimidines; Research; Sarcoma; Sarcoma 180; Uracil	1963
[ON THE EFFECT OF CERTAIN PYRIMIDINE DERIVATIVES ON THE METASTASIZATION OF TRANSPLANTABLE SSK RAT SARCOMA]. Voprosy onkologii, 1964, Volume: 10 Topics: Cytosine; Neoplasm Metastasis; Neoplasms; Pharmacology; Pyrimidines; Rats; Research; Sarcoma; Sarcoma, Experimental; Thymine	1964
PYRIMIDINE DERIVATIVES. V. SYNTHESIS OF SUBSTITUTED PYRIMIDINES FROM 4-AMINO-6-CHLORO-2-METHYLTHIOPYRIMIDINE. Journal of medicinal chemistry, 1964, Volume: 7 Topics: Antineoplastic Agents; Biological Assay; Chemistry, Pharmaceutical; Enterococcus faecalis; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyrimidines; Research; Spectrum Analysis; Tissue Culture Techniques	1964
CEREBELLAR ATAXIA ASSOCIATED WITH FLUORINATED PYRIMIDINE THERAPY. Cancer chemotherapy reports, 1964, Volume: 41 Topics: Ataxia; Cerebellar Ataxia; Cerebellar Diseases; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Neoplasms; Pyrimidines; Toxicology	1964
GROWTH INHIBITION OF CLOSTRIDIUM FESERI BY CARCINOSTATIC PURINE AND PYRIMIDINE ANALOGS. I. EFFECT OF MEDIUM ON GROWTH INHIBITION. Cancer research, 1964, Volume: 24 Topics: Adenocarcinoma; Antineoplastic Agents; Clostridium; Culture Media; Neoplasms; Neoplasms, Experimental; Pharmacology; Purines; Pyrimidines; Research; Tissue Culture Techniques	1964
METABOLIC STUDIES ON THE SUGARS OF NUCLEIC ACIDS. I. THE ISOLATION OF PYRIMIDINE-BOUND SUGARS AND UTILIZATION OF (14C6)GLUCOSE FOR RIBOSE FORMATION IN MAMMALIAN TISSUES IN VITRO. Biochimica et biophysica acta, 1964, Aug-12, Volume: 87 Topics: Animals; Carbohydrate Metabolism; Carcinoma, Ehrlich Tumor; Glucose; In Vitro Techniques; Liver; Mice; Neoplasms; Nucleic Acids; Nucleosides; Nucleotides; Purines; Pyrimidines; Rats; Research; Ribose; RNA; RNA, Neoplasm; Spleen; Thymus Gland	1964
[RESULTS OF THE TREATMENT OF RATS WITH TRANSPLANTED SARCOMA SSK WITH THIOTEPA ASSOCIATED WITH SOME PYRIMIDINE DERIVATIVES]. Voprosy onkologii, 1964, Volume: 10 Topics: Antineoplastic Agents; Neoplasm Transplantation; Neoplasms; Pharmacology; Pyrimidines; Research; Sarcoma; Sarcoma, Experimental; Thiotepa	1964
[TRIAL TREATMENT OF VARIOUS "PROTEUS" INFECTIONS WITH 2,4-DIAMINO-5-(3,4,5-TRIMETHOXYBENZYL) PYRIMIDINE, OR (TRIM'ETHOPRIME)]. La Presse medicale, 1965, Mar-27, Volume: 73 Topics: Drug Synergism; Drug Therapy; Folic Acid; Hematologic Diseases; Humans; Metabolism; Neoplasms; Polymethacrylic Acids; Proteus; Proteus Infections; Pyrimidines; Respiratory Tract Infections; Sepsis; Skin Diseases; Sulfonamides; Urinary Tract Infections	1965
PYRIMIDINE DERIVATIVES. VI. 2,4,5-TRIAMINO-6-CHLORO- AND -6-MERCAPTOPYRIMIDINE AND RELATED COMPOUNDS. Journal of medicinal chemistry, 1964, Volume: 7 Topics: Antineoplastic Agents; Chemistry, Pharmaceutical; Enterococcus faecalis; Mice; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyrimidines; Research; Spectrum Analysis	1964
RADIOSENSITIZATION OF TUMORS WITH PYRIMIDINE DERIVATIVES. Acta - Unio Internationalis Contra Cancrum, 1964, Volume: 20 Topics: Animals; Carcinoma, Ehrlich Tumor; Melanoma; Mice; Neoplasm Transplantation; Neoplasms; Neoplasms, Experimental; Pharmacology; Pyrimidines; Radiation Effects; Research; Skin Neoplasms; Uracil	1964
PYRIMIDINE METABOLISM IN TISSUE CULTURE CELLS DERIVED FROM RAT HEPATOMAS. I. SUSPENSION CELL CULTURES DERIVED FROM THE NOVIKOFF HEPATOMA. Cancer research, 1965, Volume: 25 Topics: Animals; Carcinoma, Hepatocellular; Cell Culture Techniques; Floxuridine; Fluorouracil; Glycine; Liver Neoplasms; Liver Neoplasms, Experimental; Metabolism; Methotrexate; Mutation; Neoplasms; Neoplasms, Experimental; Nucleosides; Pharmacology; Pyrimidines; Rats; Research; Serine; Thymidine; Thymidine Kinase; Thymine; Tissue Culture Techniques; Toxicology; Uracil	1965
The biochemical activity of 6-azauridine: interference with pyrimidine metabolism in transplantable mouse tumors. The Journal of biological chemistry, 1959, Volume: 234 Topics: Animals; Azauridine; Mice; Neoplasm Transplantation; Neoplasms; Nucleosides; Nucleotides; Pyrimidines	1959
The combined effect of a tumor inhibitor (5-amino 7-hydroxy-1 H-V-triazolo (d) pyrimidine) and X-Ray therapy. Radiology, 1950, Volume: 55, Issue:6 Topics: Guanine; Humans; Neoplasms; Pyrimidines; X-Ray Therapy	1950
The action of some pyrimidine derivatives and related compounds on sarcoma development in grafted mice. British journal of cancer, 1951, Volume: 5, Issue:1 Topics: Animals; Mice; Neoplasms; Pyrimidines; Sarcoma	1951
The effect of 5-amino-7-hydroxy-1H-v-triazolo (d) pyrimidine (guanazolo) on variety of neoplasms in experimental animals. Cancer research, 1950, Volume: 10, Issue:3 Topics: Animals; Azaguanine; Neoplasms; Pyrimidines	1950
Anti-cancer activities of 5-acyl-6-[2-hydroxy/benzyloxy-3-(amino)-propylamino]-1,3-dialkyl-1H-pyrimidin-2,4-diones. Bioorganic & medicinal chemistry, 2006, Dec-15, Volume: 14, Issue:24 Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Piperidines; Propanolamines; Pyrimidines; Pyrimidinones; Pyrrolidines; Structure-Activity Relationship	2006
Syntheses and anti-cancer activities of 2-[1-(indol-3-yl-/pyrimidin-5-yl-/pyridine-2-yl-/quinolin-2-yl)-but-3-enylamino]-2-phenyl-ethanols. Bioorganic & medicinal chemistry, 2007, Mar-15, Volume: 15, Issue:6 Topics: Antineoplastic Agents; Cell Proliferation; Drug Screening Assays, Antitumor; Humans; Indoles; Molecular Structure; Neoplasms; Pyridines; Pyrimidines; Quinolines; Structure-Activity Relationship; Tumor Cells, Cultured	2007
Autophagy suppresses tumor progression by limiting chromosomal instability. Genes & development, 2007, Jun-01, Volume: 21, Issue:11 Topics: Animals; Apoptosis; Apoptosis Regulatory Proteins; Aspartic Acid; Autophagy; Autophagy-Related Protein 5; Beclin-1; Blotting, Western; Cells, Cultured; Centrosome; Chromosomal Instability; Chromosome Aberrations; Disease Progression; DNA Damage; Epithelial Cells; Fluorescent Antibody Technique; Kidney; Loss of Heterozygosity; Metabolism; Mice; Mice, Knockout; Microtubule-Associated Proteins; Neoplasms; Phosphonoacetic Acid; Ploidies; Proteins; Proto-Oncogene Proteins c-bcl-2; Pyrimidines; Signal Transduction	2007
DNA methylation and sensitivity to antimetabolites in cancer cell lines. Oncology reports, 2008, Volume: 19, Issue:2 Topics: Antimetabolites, Antineoplastic; Cell Line, Tumor; DNA Methylation; Drug Resistance, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Polymorphism, Genetic; Pyrimidines; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-3	2008
Translation of an atypical human cDNA requires fidelity of apurine-pyrimidine repeat region and recoding. Gene, 2008, May-15, Volume: 414, Issue:1-2 Topics: Amino Acid Sequence; Apurinic Acid; Base Sequence; Cloning, Molecular; DNA, Complementary; DNA, Z-Form; Humans; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Nucleic Acid Conformation; Peptide Chain Initiation, Translational; Pyrimidines; Repetitive Sequences, Nucleic Acid; RNA, Messenger; Sequence Homology, Nucleic Acid; Spermine; Transcription, Genetic; Tumor Cells, Cultured	2008
Simple gas chromatographic-mass spectrometric procedure for diagnosing pyrimidine degradation defects for prevention of severe anticancer side effects. Journal of chromatography. B, Biomedical sciences and applications, 2001, Jul-05, Volume: 758, Issue:1 Topics: Antimetabolites, Antineoplastic; Fluorouracil; Gas Chromatography-Mass Spectrometry; Neoplasms; Pyrimidines	2001