pyrimidine has been researched along with Acute Promyelocytic Leukemia in 4 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 2 (50.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bedalov, A; Dembitz, V; Kodvanj, I; Simon, JA; Tomic, B; Visnjic, D | 1 |
| Guo, Z; Hu, Y; Jin, Z; Li, H; Ma, J; Mo, J; Wang, X; Wang, Z; Wei, W; Xu, Y; Zhang, J; Zhao, J | 1 |
| Bauser, M; Brzezinka, K; Christian, S; Eheim, A; Evans, L; Ferrara, S; Friberg, A; Gradl, S; Haegebarth, A; Janzer, A; Lejeune, P; Lesche, R; Losman, JA; Merz, C; Meyer, H; Scadden, DT; Seidel, H; Stoeckigt, D; Sykes, DB; Zimmermann, K | 1 |
| Flanagan, SA; Gandhi, V; Meckling, KA | 1 |
4 other study(ies) available for pyrimidine and Acute Promyelocytic Leukemia
| Article | Year |
|---|---|
The ribonucleoside AICAr induces differentiation of myeloid leukemia by activating the ATR/Chk1 via pyrimidine depletion.
Topics: Aminoimidazole Carboxamide; AMP-Activated Protein Kinases; Cell Differentiation; Cell Line, Tumor; Checkpoint Kinase 1; Dihydroorotate Dehydrogenase; Humans; Leukemia, Promyelocytic, Acute; Oxidoreductases Acting on CH-CH Group Donors; Pyrimidines; Ribonucleosides; S Phase Cell Cycle Checkpoints | 2019 |
Arsenene: A Potential Therapeutic Agent for Acute Promyelocytic Leukaemia Cells by Acting on Nuclear Proteins.
Topics: Antineoplastic Agents; Apoptosis; Arsenicals; Cell Line, Tumor; Cell Nucleus; DNA Repair; DNA Replication; DNA-Directed DNA Polymerase; Gene Expression Regulation; Humans; Leukemia, Promyelocytic, Acute; Nanoparticles; Nuclear Proteins; Proteomics; Pyrimidines; Thioredoxins | 2020 |
The novel dihydroorotate dehydrogenase (DHODH) inhibitor BAY 2402234 triggers differentiation and is effective in the treatment of myeloid malignancies.
Topics: Animals; Antineoplastic Agents; Apoptosis; Cell Differentiation; Cell Line, Tumor; Dihydroorotate Dehydrogenase; Enzyme Inhibitors; Female; HL-60 Cells; Humans; Leukemia, Myeloid, Acute; Leukemia, Promyelocytic, Acute; Mice; Mice, Inbred NOD; Mice, SCID; Oxidoreductases Acting on CH-CH Group Donors; Pyrimidines; THP-1 Cells; Translocation, Genetic | 2019 |
Guanosine acts intracellularly to initiate apoptosis in NB4 cells: A role for nucleoside transport.
Topics: Apoptosis; Biological Transport; Caspase 3; Cell Line, Tumor; Cell Survival; Dipyridamole; DNA; DNA Fragmentation; Guanosine; Humans; Leukemia, Promyelocytic, Acute; Poly(ADP-ribose) Polymerases; Proto-Oncogene Proteins c-bcl-2; Pyrimidines | 2007 |