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pyrimidin-2-one beta-ribofuranoside and Neoplasms

pyrimidin-2-one beta-ribofuranoside has been researched along with Neoplasms in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's9 (64.29)29.6817
2010's4 (28.57)24.3611
2020's1 (7.14)2.80

Authors

AuthorsStudies
Chen, J; Chen, X; Fang, H; Guo, Z; Hu, Y; Li, Y; Lin, L; Tian, H1
Balkin, ER; Bryan, JN; Jia, F; Kumar, SR; Lewis, MR1
Bonney, PL; Dhawan, D; Fourez, LM; Fulkerson, CM; Jones, DR; Jones, PA; Klaunig, JE; Knapp, DW; Marquez, VE; Wang, Z; Wu, Q1
Butter, R; Linnekamp, JF; Medema, JP; Spijker, R; van Laarhoven, HWM1
Issa, JP1
Fu, L; Wang, XX1
Farkas, DL; Gertych, A; Tajbakhsh, J1
Hampton, T1
Cheng, JC; Chuang, J; Greer, S; Jones, PA; Liang, G; Marquez, VE; Orntoft, TF; Thykjaer, T; Weisenberger, DJ; Wozniak, C; Yoo, CB1
Bradbury, J1
Cheng, JC; Jones, PA; Yoo, CB1
Agbaria, R; Barchi, JJ; Ben-Kasus, T; Cheng, JC; Jones, PA; Kelley, JA; Marquez, VE; Rao, KV; Yoo, CB1
Agbaria, R; Ben-Kasus, T; Cheng, JC; Jones, PA; Kelley, JA; Marquez, VE; Yoo, CB1
Liu, H; Salford, LG; Sjögren, HO; Widegren, B; Xue, ZT1

Reviews

5 review(s) available for pyrimidin-2-one beta-ribofuranoside and Neoplasms

ArticleYear
Clinical and biological effects of demethylating agents on solid tumours - A systematic review.
    Cancer treatment reviews, 2017, Volume: 54

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cytidine; Decitabine; DNA Methylation; Humans; Hydralazine; Immune System; Methylation; Neoplasms; Procaine; Treatment Outcome

2017
[Recent advances in DNA demethylation in tumor therapy].
    Zhonghua bing li xue za zhi = Chinese journal of pathology, 2009, Volume: 38, Issue:5

    Topics: Animals; Cytidine; DNA Methylation; DNA Modification Methylases; Gene Knockout Techniques; Histone Acetyltransferases; Histone Deacetylase Inhibitors; Humans; Hydroxamic Acids; Neoplasms; RNA Interference; Valproic Acid

2009
Zebularine: a new drug for epigenetic therapy.
    Biochemical Society transactions, 2004, Volume: 32, Issue:Pt 6

    Topics: Azacitidine; Cytidine; DNA Methylation; Epigenesis, Genetic; Genetic Therapy; Humans; Neoplasms; Pyrimidine Nucleosides

2004
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy. The magic of its chemistry and biology.
    Nucleosides, nucleotides & nucleic acids, 2005, Volume: 24, Issue:5-7

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Cytidine; Cytidine Deaminase; DNA; Epigenesis, Genetic; Humans; Models, Chemical; Neoplasms

2005
Zebularine: a unique molecule for an epigenetically based strategy in cancer chemotherapy.
    Annals of the New York Academy of Sciences, 2005, Volume: 1058

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Cytidine; Cytidine Deaminase; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Humans; Kinetics; Models, Chemical; Neoplasms

2005

Other Studies

9 other study(ies) available for pyrimidin-2-one beta-ribofuranoside and Neoplasms

ArticleYear
Combination of epigenetic regulation with gene therapy-mediated immune checkpoint blockade induces anti-tumour effects and immune response in vivo.
    Nature communications, 2021, 11-18, Volume: 12, Issue:1

    Topics: Animals; B7-H1 Antigen; Cell Line, Tumor; Combined Modality Therapy; Cytidine; DNA Methylation; Epigenesis, Genetic; Genetic Therapy; Humans; Immune Checkpoint Inhibitors; Immunity; Immunotherapy; Methyltransferases; Neoplasm Metastasis; Neoplasms; T-Lymphocytes; Tumor Escape; Tumor Microenvironment

2021
Zebularine significantly sensitises MEC1 cells to external irradiation and radiopharmaceutical therapy when administered sequentially in vitro.
    Cell biology international, 2014, Volume: 38, Issue:2

    Topics: Apoptosis; Cell Line, Tumor; Chemoradiotherapy; Cytidine; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Humans; Neoplasms; Octreotide; Organometallic Compounds

2014
Pharmacokinetics and toxicity of the novel oral demethylating agent zebularine in laboratory and tumor bearing dogs.
    Veterinary and comparative oncology, 2017, Volume: 15, Issue:1

    Topics: Administration, Oral; Aldehyde Oxidase; Animals; Chromatography, High Pressure Liquid; Cytidine; Cytosol; DNA Methylation; Dog Diseases; Dogs; Female; Half-Life; Indiana; Liver; Macrolides; Male; Neoplasms; Neutropenia; Schools, Veterinary

2017
Cancer prevention: epigenetics steps up to the plate.
    Cancer prevention research (Philadelphia, Pa.), 2008, Volume: 1, Issue:4

    Topics: Antimetabolites, Antineoplastic; Azacitidine; Cell Transformation, Neoplastic; Chemoprevention; Cytidine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Epigenesis, Genetic; Humans; Models, Biological; Neoplasms

2008
Measuring topology of low-intensity DNA methylation sites for high-throughput assessment of epigenetic drug-induced effects in cancer cells.
    Experimental cell research, 2010, Nov-15, Volume: 316, Issue:19

    Topics: Antineoplastic Agents; Azacitidine; Cell Line, Tumor; Cell Nucleus; Cytidine; Cytosine; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Fluorescence; High-Throughput Screening Assays; Humans; Indoles; Neoplasms; Nucleic Acid Conformation

2010
Scientists probe shutting down cancer cells by awakening silenced genes.
    JAMA, 2004, May-19, Volume: 291, Issue:19

    Topics: Animals; Antineoplastic Agents; Cytidine; DNA Methylation; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Neoplasms; Pyrimidine Nucleosides

2004
Preferential response of cancer cells to zebularine.
    Cancer cell, 2004, Volume: 6, Issue:2

    Topics: Antineoplastic Agents; Cell Division; Cell Line, Tumor; Cytidine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA, Neoplasm; Fibroblasts; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, p16; Humans; Neoplasms; Pyrimidine Nucleosides

2004
Zebularine: a candidate for epigenetic cancer therapy.
    Drug discovery today, 2004, Nov-01, Volume: 9, Issue:21

    Topics: Antineoplastic Agents; Cytidine; Epigenesis, Genetic; Humans; Neoplasms; Pyrimidine Nucleosides

2004
Low dose Zebularine treatment enhances immunogenicity of tumor cells.
    Cancer letters, 2007, Nov-08, Volume: 257, Issue:1

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cytidine; Cytokines; DNA Methylation; Dose-Response Relationship, Drug; Immunosuppressive Agents; Male; Neoplasms; Rats; Reverse Transcriptase Polymerase Chain Reaction; Spleen; Transfection

2007