pyrimethamine has been researched along with Toxoplasmosis, Animal in 83 studies
Maloprim: contains above 2 cpds
Toxoplasmosis, Animal: Acquired infection of non-human animals by organisms of the genus TOXOPLASMA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A substantial reduction of brain cyst numbers could be obtained through a six week therapy with SDDS-pyrimethamine combination or a high titer anti-Toxoplasma serum." | 7.65 | The effect of chemo-immunotherapy with SDDS, pyrimethamine and anti-toxoplasma serum on toxoplasma gondii cysts in latent infected NMRI mice. ( Adusu, E; Masihi, KN; Tischer, I; Werner, H, 1977) |
| "Toxoplasmosis is a disease with a worldwide distribution and significant morbidity and mortality." | 5.91 | Mefloquine loaded niosomes as a promising approach for the treatment of acute and chronic toxoplasmosis. ( Aboul Asaad, IA; Amer, BS; Carter, WG; El Maghraby, GM; El Sharazly, BM; Ismail, HIH; Mohamed, DA; Yassen, NA, 2023) |
| "A substantial reduction of brain cyst numbers could be obtained through a six week therapy with SDDS-pyrimethamine combination or a high titer anti-Toxoplasma serum." | 3.65 | The effect of chemo-immunotherapy with SDDS, pyrimethamine and anti-toxoplasma serum on toxoplasma gondii cysts in latent infected NMRI mice. ( Adusu, E; Masihi, KN; Tischer, I; Werner, H, 1977) |
| " Azithromycin is also effective against intracystic bradyzoïtes in vitro, but long term administration of azithromycin to chronically infected mice failed to reduce the mean number of brain cysts." | 2.39 | [New pathogens and mode of action of azithromycin: Toxoplasma gondii]. ( Derouin, F, 1995) |
| "In patients with AIDS, toxoplasmosis is the most common cause of CNS mass lesions." | 2.38 | Toxoplasmosis in AIDS patients. ( Tuazon, CU, 1989) |
| "Toxoplasmosis is a disease with a worldwide distribution and significant morbidity and mortality." | 1.91 | Mefloquine loaded niosomes as a promising approach for the treatment of acute and chronic toxoplasmosis. ( Aboul Asaad, IA; Amer, BS; Carter, WG; El Maghraby, GM; El Sharazly, BM; Ismail, HIH; Mohamed, DA; Yassen, NA, 2023) |
| "Drug treatment for toxoplasmosis is problematic, because current drugs cannot eradicate latent infection with Toxoplasma gondii and can cause bone marrow toxicity." | 1.46 | Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites. ( Kato, K; Murata, Y; Sugi, T; Weiss, LM, 2017) |
| "Pyrimethamine was radioiodinated with I-131." | 1.39 | Preparation of (131)I-Pyrimethamine and evaluation for scintigraphy of experimentally Toxoplasma gondii-infected rats. ( Baykara, B; Bekis, R; Durkan, K; Inceboz, T; Surucu, E; Uner, A; Yavasoglu, A; Yilmaz, O; Yurt Lambrecht, F, 2013) |
| "Fluconazole is an important antifungal triazole used against others CNS related opportunistic pathogens such as Cryptococcus neoformans and Candida spp." | 1.39 | Toxoplasma gondii: the effect of fluconazole combined with sulfadiazine and pyrimethamine against acute toxoplasmosis in murine model. ( de Souza, W; Martins-Duarte, ÉS; Vommaro, RC, 2013) |
| " Three doses of 200, 300 and 400 mg/kg DFO were used either alone or in combination with pyrimethamine." | 1.30 | Effect of deferoxamine alone and combined with pyrimethamine on acute toxoplasmosis in mice. ( Mahmoud, MS, 1999) |
| " Extending these experiments, we have now shown that roxithromycin at doses of 400 or 200 mg/kg/day combined with dapsone at doses of 5, 25 or 50 mg/kg/day completely prevented the development of T." | 1.30 | Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. ( Brun-Pascaud, M; Chau, F; Derouin, F; Girard, PM, 1998) |
| "Treatment with pyrimethamine and sulfamethoxazolum combination administered via intragastric route, was started 2 hours after each mouse received an intraperitoneal injection of a lethal inoculum of 5 x 10(3) tachyzoites of RH strain toxoplasma gondii and the therapy was lasted for 52 days." | 1.30 | [Preliminary application of PCR to curative effect assessment of chemotherapy against experimental acute infection of Toxoplasma gondii in mice]. ( Ke, OY; Xiang, X; Zhang, Z, 1997) |
| "The efficacy of roxithromycin alone or in combination with pyrimethamine or sulphadiazine was examined in vitro and in a murine model of acute toxoplasmosis." | 1.29 | In-vitro and in-vivo activities of roxithromycin in combination with pyrimethamine or sulphadiazine against Toxoplasma gondii. ( Bryskier, A; Derouin, F; Moutot, M; Romand, S, 1995) |
| " The dosage regimen for pyrimethamine and sulfadiazine was established by pharmacokinetic studies in two monkeys." | 1.29 | Study of treatment of congenital Toxoplasma gondii infection in rhesus monkeys with pyrimethamine and sulfadiazine. ( Baars, I; Camps, W; Eskes, T; Galama, J; Melchers, W; Meuwissen, J; Schoondermark-van de Ven, E; Vree, T, 1995) |
| "Treatment with pyrimethamine at 12." | 1.29 | Treatment of acute Toxoplasma gondii infections in mice with diclazuril or a combination of diclazuril and pyrimethamine. ( Blagburn, BL; Lindsay, DS; Rippey, NS, 1995) |
| "The efficacy of atovaquone alone or combined with pyrimethamine, sulfadiazine, clarithromycin, and minocycline was examined in vitro and in a murine model of acute toxoplasmosis." | 1.29 | In vitro and in vivo activities of the hydroxynaphthoquinone atovaquone alone or combined with pyrimethamine, sulfadiazine, clarithromycin, or minocycline against Toxoplasma gondii. ( Derouin, F; Pudney, M; Romand, S, 1993) |
| "The activity of atovaquone in the treatment of murine toxoplasmosis was greatly enhanced when administered in combination with pyrimethamine or sulfadiazine." | 1.29 | The activity of atovaquone (566C80) in murine toxoplasmosis is markedly augmented when used in combination with pyrimethamine or sulfadiazine. ( Araujo, FG; Lin, T; Remington, JS, 1993) |
| "Treatment with pyrimethamine plus sulfadiazine produced clinical cures in 100% of the infected mice 1 month after infection." | 1.29 | A clinical-parasitological monotherapy cure in the treatment of experimental infection by a highly virulent strain of Toxoplasma gondii. ( Arribas, JR; de Diego, JA; Penin, P; Vázquez, E; Vázquez, JJ, 1996) |
| "The activity of the macrolide antibiotic clarithromycin was examined alone or in combination with other drugs for the treatment of acute or chronic infections with Toxoplasma gondii in mice." | 1.28 | Activity of clarithromycin alone or in combination with other drugs for treatment of murine toxoplasmosis. ( Araujo, FG; Lin, T; Prokocimer, P; Remington, JS, 1992) |
| "Pyrimethamine was administered in mouse chow at concentrations of 0, 0." | 1.28 | Pyrimethamine concentrations in serum during treatment of acute murine experimental toxoplasmosis. ( Luft, BJ; Tanowitz, HB; Weiss, LM; Wittner, M, 1992) |
| "Dapsone alone, which was administered at 100 mg/kg/day for 10 days from day 1 after infection, was unable to prevent parasite dissemination and only delayed the time to death of treated mice compared with the time of death of untreated controls." | 1.28 | Anti-Toxoplasma effects of dapsone alone and combined with pyrimethamine. ( Chastang, C; Chau, F; Derouin, F; Piketty, C; Pocidalo, JJ; Rouveix, B, 1991) |
| "The activity of recombinant gamma interferon (rIFN-gamma) in combination with either pyrimethamine or clindamycin was examined in a murine model of acute toxoplasmosis." | 1.28 | Activity of gamma interferon in combination with pyrimethamine or clindamycin in treatment of murine toxoplasmosis. ( Israelski, D; Remington, J, 1990) |
| "When pyrimethamine was administered from day 1, 7 of 11 mice died within 25 days; by determination of parasitic loads, the effect of pyrimethamine was only demonstrable from day 6, and a relapse was constantly observed after the cessation of therapy." | 1.28 | In vivo assessment of antimicrobial agents against Toxoplasma gondii by quantification of parasites in the blood, lungs, and brain of infected mice. ( Derouin, F; Piketty, C; Pocidalo, JJ; Rouveix, B, 1990) |
| "Zidovudine was found to antagonize the toxoplasmacidal effect of low concentrations of pyrimethamine in vitro, and in vitro synergism of pyrimethamine and sulfadiazine against T." | 1.28 | Zidovudine antagonizes the action of pyrimethamine in experimental infection with Toxoplasma gondii. ( Israelski, DM; Remington, JS; Tom, C, 1989) |
| "Five drug regimens for the treatment of acute toxoplasmosis were compared in a monkey model." | 1.27 | Five drug regimens for treatment of acute toxoplasmosis in squirrel monkeys. ( Harper, JS; London, WT; Sever, JL, 1985) |
| "Trimethoprim was found to have no effect." | 1.25 | Chemotherapy in experimental toxoplasmosis: comparison of the efficacy of trimethoprim-sulfur and pyrimethamine-sulfur combinations. ( Seah, SK, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (46.99) | 18.7374 |
| 1990's | 34 (40.96) | 18.2507 |
| 2000's | 3 (3.61) | 29.6817 |
| 2010's | 6 (7.23) | 24.3611 |
| 2020's | 1 (1.20) | 2.80 |
| Authors | Studies |
|---|---|
| Rosowsky, A | 1 |
| Papoulis, AT | 1 |
| Forsch, RA | 1 |
| Queener, SF | 1 |
| Wei, S | 1 |
| Daniel, BJ | 1 |
| Brumlik, MJ | 1 |
| Burow, ME | 1 |
| Zou, W | 1 |
| Khan, IA | 1 |
| Wadsworth, S | 1 |
| Siekierka, J | 1 |
| Curiel, TJ | 1 |
| El Sharazly, BM | 1 |
| Aboul Asaad, IA | 1 |
| Yassen, NA | 1 |
| El Maghraby, GM | 1 |
| Carter, WG | 1 |
| Mohamed, DA | 1 |
| Amer, BS | 1 |
| Ismail, HIH | 1 |
| Murata, Y | 1 |
| Sugi, T | 1 |
| Weiss, LM | 2 |
| Kato, K | 1 |
| Montazeri, M | 1 |
| Emami, S | 1 |
| Asgarian-Omran, H | 1 |
| Azizi, S | 1 |
| Sharif, M | 1 |
| Sarvi, S | 1 |
| Rezaei, F | 1 |
| Sadeghi, M | 1 |
| Gohardehi, S | 1 |
| Daryani, A | 1 |
| Silva, LA | 1 |
| Fernandes, MD | 1 |
| Machado, AS | 1 |
| Reis-Cunha, JL | 1 |
| Bartholomeu, DC | 1 |
| Almeida Vitor, RW | 1 |
| Pissinate, K | 1 |
| dos Santos Martins-Duarte, É | 1 |
| Schaffazick, SR | 1 |
| de Oliveira, CP | 1 |
| Vommaro, RC | 2 |
| Guterres, SS | 1 |
| Pohlmann, AR | 1 |
| de Souza, W | 2 |
| Lamberton, PH | 2 |
| Donnelly, CA | 2 |
| Webster, JP | 2 |
| Inceboz, T | 1 |
| Yurt Lambrecht, F | 1 |
| Surucu, E | 1 |
| Yilmaz, O | 1 |
| Yavasoglu, A | 1 |
| Durkan, K | 1 |
| Baykara, B | 1 |
| Bekis, R | 1 |
| Uner, A | 1 |
| Martins-Duarte, ÉS | 1 |
| Mahmoud, MS | 1 |
| NAKAYAMA, I | 1 |
| MATSUBAYASHI, H | 1 |
| FRANCOIS, J | 1 |
| JADIN, J | 1 |
| WERY, M | 1 |
| VANDECASTEELE, J | 1 |
| GILES, CL | 1 |
| JACOBS, L | 2 |
| MELTON, ML | 2 |
| MALONEY, ED | 1 |
| KAUFMAN, HE | 1 |
| TSUNODA, K | 1 |
| SUZUKI, K | 1 |
| ITO, S | 1 |
| TSUTSUMI, Y | 1 |
| PETRAK, M | 1 |
| CARPENTER, J | 1 |
| Torrey, EF | 1 |
| Garin, JP | 2 |
| Paillard, B | 1 |
| Nguyen, BT | 1 |
| Stadtsbaeder, S | 1 |
| Bonardi, R | 1 |
| Tabbara, KF | 1 |
| Sakuragi, S | 1 |
| O'Connor, GR | 1 |
| Frenkel, JK | 2 |
| Smith, DD | 1 |
| Blais, J | 1 |
| Tardif, C | 1 |
| Chamberland, S | 2 |
| Romand, S | 2 |
| Bryskier, A | 1 |
| Moutot, M | 1 |
| Derouin, F | 9 |
| Mehlhorn, H | 1 |
| Dankert, W | 1 |
| Hartman, PG | 1 |
| Then, RL | 1 |
| Schoondermark-van de Ven, E | 1 |
| Galama, J | 1 |
| Vree, T | 1 |
| Camps, W | 1 |
| Baars, I | 1 |
| Eskes, T | 1 |
| Meuwissen, J | 1 |
| Melchers, W | 1 |
| Lindsay, DS | 1 |
| Rippey, NS | 1 |
| Blagburn, BL | 1 |
| Alder, J | 1 |
| Hutch, T | 1 |
| Meulbroek, JA | 1 |
| Clement, JC | 1 |
| Brun-Pascaud, M | 3 |
| Chau, F | 5 |
| Simonpoli, AM | 1 |
| Girard, PM | 3 |
| Pocidalo, JJ | 4 |
| Araujo, FG | 4 |
| Slifer, T | 1 |
| Remington, JS | 5 |
| Pudney, M | 1 |
| Lin, T | 2 |
| Buxton, D | 1 |
| Thomson, KM | 1 |
| Maley, S | 1 |
| Richards, FO | 1 |
| Kovacs, JA | 2 |
| Luft, BJ | 2 |
| Gross, U | 1 |
| Pohl, F | 1 |
| Garry, L | 1 |
| Jacobus, D | 1 |
| de Diego, JA | 1 |
| Penin, P | 1 |
| Arribas, JR | 1 |
| Vázquez, E | 1 |
| Vázquez, JJ | 1 |
| Miédougé, M | 1 |
| Bessières, MH | 1 |
| Cassaing, S | 1 |
| Swierczynski, B | 1 |
| Séguéla, JP | 1 |
| Eskes, TK | 2 |
| Schoondermark-van de Ven, EM | 1 |
| Melchers, WJ | 1 |
| Galama, JM | 1 |
| Meuwissen, JH | 1 |
| Aguirre-Cruz, L | 2 |
| Sotelo, J | 2 |
| Velasco, O | 1 |
| Xiang, X | 1 |
| Ke, OY | 1 |
| Zhang, Z | 1 |
| el-Tombary, AA | 1 |
| Ismail, KA | 1 |
| Aboulwafa, OM | 1 |
| Omar, AM | 1 |
| el-Azzouni, MZ | 1 |
| el-Mansoury, ST | 1 |
| Werner, H | 4 |
| Matuschka, FR | 1 |
| Brandenburg, I | 1 |
| Thiermann, E | 1 |
| Apt, W | 1 |
| Atias, A | 1 |
| Lorca, M | 1 |
| Olguín, J | 1 |
| Masihi, KN | 1 |
| Tischer, I | 1 |
| Adusu, E | 1 |
| Moorhouse, DE | 1 |
| Coradello, H | 1 |
| Kretschmer, S | 1 |
| Katz, D | 1 |
| Dubey, JP | 2 |
| Yeary, RA | 1 |
| Sheffield, HG | 1 |
| Seah, SK | 1 |
| Almadany, R | 1 |
| Rouveix, B | 3 |
| Prokocimer, P | 1 |
| Tanowitz, HB | 1 |
| Wittner, M | 1 |
| Chang, HR | 1 |
| Comte, R | 1 |
| Piguet, PF | 1 |
| Pechère, JC | 1 |
| Piketty, C | 2 |
| Chastang, C | 1 |
| Current, WL | 1 |
| Israelski, D | 1 |
| Remington, J | 1 |
| Tassignon, MJ | 1 |
| Brihaye, M | 1 |
| De Meuter, F | 1 |
| Vercruysse, A | 1 |
| Van Hoof, F | 1 |
| De Wilde, F | 1 |
| Tuazon, CU | 1 |
| Israelski, DM | 1 |
| Tom, C | 1 |
| Hou, XP | 1 |
| Tao, F | 1 |
| Yi, YY | 1 |
| Wang, WL | 1 |
| Allegra, CJ | 1 |
| Chabner, BA | 1 |
| Swan, JC | 1 |
| Drake, J | 1 |
| Lunde, M | 1 |
| Parrillo, JE | 1 |
| Masur, H | 1 |
| Bakhtari, SK | 1 |
| Jíra, J | 1 |
| Guptill, DR | 1 |
| Brossier, N | 1 |
| Tran Manh Sung, R | 1 |
| Moyne, T | 1 |
| Harper, JS | 1 |
| London, WT | 1 |
| Sever, JL | 1 |
| Vischer, WA | 1 |
| Egger, I | 1 |
| Markus, MB | 1 |
| Dannemann, R | 1 |
| Zigas, V | 1 |
| Benfante, RJ | 1 |
| Krogstad, DJ | 1 |
| Juranek, DD | 1 |
| Walls, KW | 1 |
| Zardi, O | 1 |
| Adorisio, E | 1 |
| Nobili, G | 1 |
| Lattanzi, MT | 1 |
| Miller, NL | 1 |
| Terragna, A | 1 |
| La Fauci, MF | 1 |
6 reviews available for pyrimethamine and Toxoplasmosis, Animal
| Article | Year |
|---|---|
[New pathogens and mode of action of azithromycin: Toxoplasma gondii].
Topics: Animals; Anti-Bacterial Agents; Azithromycin; Drug Synergism; Drug Therapy, Combination; Humans; In | 1995 |
Preventing toxoplasmic encephalitis in persons infected with human immunodeficiency virus.
Topics: AIDS-Related Opportunistic Infections; Animals; Anti-Infective Agents; Cats; Dapsone; Drug Therapy, | 1995 |
Influence of antimicrobial agents on replication and stage conversion of Toxoplasma gondii.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cells, Cultured; Clindamycin; Humans; Pyrimet | 1996 |
Toxoplasmosis.
Topics: Animals; Child; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Pregnancy; Pr | 1976 |
Toxoplasmosis in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Animals; Drug Therapy, Combination; Humans; Mice; Opportunistic | 1989 |
Toxoplasma and toxoplasmosis.
Topics: Abortion, Habitual; Animals; Antigen-Antibody Reactions; Female; Hodgkin Disease; Humans; Intellectu | 1967 |
77 other studies available for pyrimethamine and Toxoplasmosis, Animal
| Article | Year |
|---|---|
Synthesis and antiparasitic and antitumor activity of 2, 4-diamino-6-(arylmethyl)-5,6,7,8-tetrahydroquinazoline analogues of piritrexim.
Topics: Animals; Antifungal Agents; Antineoplastic Agents; Antiprotozoal Agents; Cell Line; Drug Screening A | 1999 |
Drugs designed to inhibit human p38 mitogen-activated protein kinase activation treat Toxoplasma gondii and Encephalitozoon cuniculi infection.
Topics: Animals; Antiprotozoal Agents; CD8 Antigens; Dose-Response Relationship, Drug; Drug Design; Drug Syn | 2007 |
Mefloquine loaded niosomes as a promising approach for the treatment of acute and chronic toxoplasmosis.
Topics: Animals; Liposomes; Mefloquine; Mice; Pyrimethamine; Sulfadiazine; Toxoplasma; Toxoplasmosis; Toxopl | 2023 |
Identification of compounds that suppress Toxoplasma gondii tachyzoites and bradyzoites.
Topics: Abietanes; Animals; Antiprotozoal Agents; Cell Line; Chlorocebus aethiops; Host-Parasite Interaction | 2017 |
In vitro and in vivo evaluation of kojic acid against Toxoplasma gondii in experimental models of acute toxoplasmosis.
Topics: Animals; Antioxidants; Antiprotozoal Agents; Apoptosis; Cell Survival; Chlorocebus aethiops; Female; | 2019 |
Efficacy of sulfadiazine and pyrimetamine for treatment of experimental toxoplasmosis with strains obtained from human cases of congenital disease in Brazil.
Topics: Alcohol Dehydrogenase; Animals; Antiprotozoal Agents; Female; Genotype; Humans; Infant, Newborn; Mic | 2019 |
Pyrimethamine-loaded lipid-core nanocapsules to improve drug efficacy for the treatment of toxoplasmosis.
Topics: Animals; Cell Line; Cell Survival; Coccidiostats; Female; Lipids; Macrophages, Peritoneal; Mice; Nan | 2014 |
Specificity of the Toxoplasma gondii-altered behaviour to definitive versus non-definitive host predation risk.
Topics: Animals; Behavior, Animal; Cats; Dapsone; Haloperidol; Pyrimethamine; Rats; Species Specificity; Tox | 2008 |
Preparation of (131)I-Pyrimethamine and evaluation for scintigraphy of experimentally Toxoplasma gondii-infected rats.
Topics: Animals; Antiprotozoal Agents; Disease Models, Animal; Drug Compounding; Drug Stability; Iodine Radi | 2013 |
Toxoplasma gondii: the effect of fluconazole combined with sulfadiazine and pyrimethamine against acute toxoplasmosis in murine model.
Topics: Acute Disease; Animals; Antifungal Agents; Antiprotozoal Agents; Cell Line; Cell Survival; Disease M | 2013 |
Effect of deferoxamine alone and combined with pyrimethamine on acute toxoplasmosis in mice.
Topics: Acute Disease; Animals; Antiprotozoal Agents; Deferoxamine; Disease Models, Animal; Drug Therapy, Co | 1999 |
EFFECTS OF SPIRAMYCINE ON EXPERIMENTAL TOXOPLASMOSIS IN MICE.
Topics: Brain; Mice; Pyridazines; Pyrimethamine; Research; Spiramycin; Toxoplasmosis; Toxoplasmosis, Animal | 1963 |
[TREATMENT OF TOXOPLASMOSIS. (EXPERIMENTAL STUDY)].
Topics: Anilides; Animals; Anti-Bacterial Agents; Colistin; Mice; Oxytetracycline; Penicillin V; Pyrimethami | 1963 |
EXPERIMENTAL USE OF FOLINIC ACID IN THE TREATMENT OF TOXOPLASMOSIS WITH PYRIMETHAMINE.
Topics: Eye; Folic Acid; Injections; Injections, Intraperitoneal; Injections, Subcutaneous; Leucovorin; Mice | 1964 |
MULTIPLICATION AND THERAPY OF TOXOPLASMA GONDII IN TISSUE CULTURE.
Topics: Animals; Mice; Pharmacology; Pyrimethamine; Research; Temperature; Tissue Culture Techniques; Toxopl | 1964 |
EFFECTS OF SULFAMONOMETHOXINE ALONE AND WITH PYRIMETHAMINE UPON PIGS EXPERIMENTALLY INFECTED WITH TOXOPLASMA.
Topics: Animals; Mice; Pharmacology; Pyrimethamine; Research; Sulfamonomethoxine; Sulfanilamide; Sulfanilami | 1965 |
FELINE TOXOPLASMOSIS.
Topics: Animals; Anorexia Nervosa; Blood; Cat Diseases; Cats; Drug Therapy; Dyspnea; Iritis; Pathology; Pyri | 1965 |
Parasites as causative agents of human affective disorders? The impact of anti-psychotic, mood-stabilizer and anti-parasite medication on Toxoplasma gondii's ability to alter host behaviour.
Topics: Animals; Antimanic Agents; Antiprotozoal Agents; Antipsychotic Agents; Behavior, Animal; Cats; Dapso | 2006 |
[Experimental toxoplasmosis in mice. Comparative activity of clindamycin, midecamycin, josamycin, spiramycin, pyrimethamine-sulfadoxine, and trimethoprim-sulfamethoxazole].
Topics: Animals; Clindamycin; Drug Combinations; Leucomycins; Mice; Pyrimethamine; Sulfadoxine; Sulfamethoxa | 1984 |
Comparative effects of cotrimoxazole (trimethoprim-sulphamethoxazole), pyrimethamine-sulphadiazine and spiramycin during avirulent infection with Toxoplasma gondii (Beverley strain) in mice.
Topics: Animals; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Leucomyci | 1983 |
[Toxoplasmosis].
Topics: Adult; Animals; Antibodies; Antimalarials; Drug Therapy, Combination; Female; Humans; Immunologic Te | 1980 |
Minocycline in the chemotherapy of murine toxoplasmosis.
Topics: Animals; Drug Evaluation, Preclinical; Drug Therapy, Combination; Female; Male; Mice; Minocycline; P | 1982 |
Immunization of cats against shedding of Toxoplasma oocysts.
Topics: Animals; Antibodies; Cat Diseases; Cats; Feces; Immunization; Mice; Monensin; Parasite Egg Count; Py | 1982 |
Effect of clindamycin on intracellular replication, protein synthesis, and infectivity of Toxoplasma gondii.
Topics: Animals; Clindamycin; Evaluation Studies as Topic; Intracellular Fluid; Macrophages; Mice; Microbial | 1993 |
In-vitro and in-vivo activities of roxithromycin in combination with pyrimethamine or sulphadiazine against Toxoplasma gondii.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Cells, Cultured; Drug Combinations; Female; F | 1995 |
A pilot study on the efficacy of epiroprim against developmental stages of Toxoplasma gondii and Pneumocystis carinii in animal models.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Drug Therapy, Combination; Female; F | 1995 |
Study of treatment of congenital Toxoplasma gondii infection in rhesus monkeys with pyrimethamine and sulfadiazine.
Topics: Administration, Oral; Animals; Female; Half-Life; Macaca mulatta; Maternal-Fetal Exchange; Metabolic | 1995 |
Treatment of acute Toxoplasma gondii infections in mice with diclazuril or a combination of diclazuril and pyrimethamine.
Topics: Acute Disease; Animals; Coccidiostats; Drug Therapy, Combination; Female; Mice; Nitriles; Pyrimetham | 1995 |
Treatment of experimental Toxoplasma gondii infection by clarithromycin-based combination therapy with minocycline or pyrimethamine.
Topics: AIDS-Related Opportunistic Infections; Animals; Clarithromycin; Disease Models, Animal; Dose-Respons | 1994 |
Experimental evaluation of combined prophylaxis against murine pneumocystosis and toxoplasmosis.
Topics: Animals; Antifungal Agents; Antiprotozoal Agents; Atovaquone; Brain; Dapsone; Drug Therapy, Combinat | 1994 |
Rifabutin is active in murine models of toxoplasmosis.
Topics: Animals; Antiprotozoal Agents; Atovaquone; Brain; Clindamycin; Drug Therapy, Combination; Female; Mi | 1994 |
In vitro and in vivo activities of the hydroxynaphthoquinone atovaquone alone or combined with pyrimethamine, sulfadiazine, clarithromycin, or minocycline against Toxoplasma gondii.
Topics: Animals; Antiprotozoal Agents; Atovaquone; Clarithromycin; Coccidiostats; Drug Combinations; Drug In | 1993 |
The activity of atovaquone (566C80) in murine toxoplasmosis is markedly augmented when used in combination with pyrimethamine or sulfadiazine.
Topics: Animals; Antiprotozoal Agents; Atovaquone; Drug Synergism; Drug Therapy, Combination; Female; Mice; | 1993 |
Treatment of ovine toxoplasmosis with a combination of sulphamezathine and pyrimethamine.
Topics: Animals; Antibodies, Protozoan; Drug Therapy, Combination; Female; Immunoglobulin G; Immunoglobulin | 1993 |
Combination of PS-15, epiroprim, or pyrimethamine with dapsone in prophylaxis of Toxoplasma gondii and Pneumocystis carinii dual infection in a rat model.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Dapsone; Drug Therapy, Combination; Folic Acid | 1996 |
A clinical-parasitological monotherapy cure in the treatment of experimental infection by a highly virulent strain of Toxoplasma gondii.
Topics: Animals; Antiprotozoal Agents; Brain; Drug Evaluation, Preclinical; Drug Therapy, Combination; Mice; | 1996 |
Parasitemia and parasitic loads in acute infection and after anti-gamma-interferon treatment in a toxoplasmic mouse model.
Topics: Acute Disease; Animals; Anti-Infective Agents; Antibodies; Brain; Chronic Disease; Drug Therapy, Com | 1997 |
Toxoplasmosis: a scenic change and a change of therapy?
Topics: Animals; Coccidiostats; Disease Models, Animal; Macaca mulatta; Polymerase Chain Reaction; Pyrimetha | 1997 |
Prenatal diagnosis and treatment of congenital Toxoplasma gondii infections: an experimental study in rhesus monkeys.
Topics: Amniotic Fluid; Animals; Anti-Infective Agents; Disease Models, Animal; DNA, Protozoan; DNA, Ribosom | 1997 |
Lack of therapeutic effect of colchicine on murine toxoplasmosis.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Colchicine; Diarrhea; Disease Models, Animal; | 1998 |
Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Disease Models, Animal; Dose-Respons | 1998 |
Nifurtimox plus pyrimethamine for treatment of murine toxoplasmosis.
Topics: Administration, Oral; Animals; Antiprotozoal Agents; Disease Models, Animal; Dose-Response Relations | 1998 |
[Preliminary application of PCR to curative effect assessment of chemotherapy against experimental acute infection of Toxoplasma gondii in mice].
Topics: Animals; Antiprotozoal Agents; Brain; Drug Therapy, Combination; Female; Mice; Mice, Inbred BALB C; | 1997 |
Novel triazolo[4,3-a]quinazolinone and bis-triazolo[4,3-a:4,3'-c]quinazolines: synthesis and antitoxoplasmosis effect.
Topics: Animals; Anti-Infective Agents; Coccidiostats; Mice; Pyrimethamine; Quinazolines; Quinazolinones; To | 1999 |
Structural changes of Toxoplasma gondii bradyzoites and cysts following therapy with sulfamethoxypyrazine-pyrimethamine: studies by light and electron microscopy. Consequences for chemotherapy.
Topics: Animals; Brain; Drug Therapy, Combination; Female; Male; Pyrimethamine; Rodentia; Sulfalene; Sulfani | 1979 |
A comparative study of some combined treatment regimens in acute toxoplasmosis in mice.
Topics: Acute Disease; Animals; Clindamycin; Drug Therapy, Combination; Humans; Leucomycins; Mice; Pyrimetha | 1978 |
The effect of chemo-immunotherapy with SDDS, pyrimethamine and anti-toxoplasma serum on toxoplasma gondii cysts in latent infected NMRI mice.
Topics: Animals; Brain Diseases; Cysts; Dapsone; Female; Immunotherapy; Mice; Mice, Inbred Strains; Pyrimeth | 1977 |
Toxoplasmosis.
Topics: Animals; Cats; Cattle; Female; Humans; Meat; Pregnancy; Pyrimethamine; Sheep; Sulfonamides; Swine; T | 1977 |
[A comparison of Ultrax, Diazil, Bactrim and Spiramycin in experimental toxoplasmosis in mice (author's transl)].
Topics: Animals; Injections, Subcutaneous; Leucomycins; Mice; Pyrimethamine; Sulfameter; Sulfamethazine; Sul | 1978 |
Anticoccidial activity of 2-sulfamoyl-4,4-diaminodiphenylsulfone, sulfadiazine, pyrimethamine and clindamycin in cats infected with Toxoplasma gondii.
Topics: Animals; Cat Diseases; Cats; Clindamycin; Coccidiostats; Pyrimethamine; Sulfadiazine; Sulfonamides; | 1977 |
Effects of pyrimethamine and sulfadiazine on the intestinal development of Toxoplasma gondii in cats.
Topics: Animals; Antibody Formation; Cat Diseases; Cats; Immunization; Intestines; Parasite Egg Count; Pyrim | 1976 |
Chemotherapy in experimental toxoplasmosis: comparison of the efficacy of trimethoprim-sulfur and pyrimethamine-sulfur combinations.
Topics: Animals; Drug Combinations; Drug Evaluation; Female; Mice; Pyrimethamine; Sulfadiazine; Sulfamethoxa | 1975 |
Synergistic activity of azithromycin and pyrimethamine or sulfadiazine in acute experimental toxoplasmosis.
Topics: Animals; Azithromycin; Brain; Drug Synergism; Drug Therapy, Combination; Erythromycin; Female; Lung; | 1992 |
Activity of clarithromycin alone or in combination with other drugs for treatment of murine toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Animals; Brain Diseases; Chronic Disease; Clarith | 1992 |
Pyrimethamine concentrations in serum during treatment of acute murine experimental toxoplasmosis.
Topics: Acute Disease; Animals; Biological Availability; Mice; Pyrimethamine; Toxoplasmosis, Animal; Toxopla | 1992 |
Activity of minocycline against Toxoplasma gondii infection in mice.
Topics: Acute Disease; Animals; Chronic Disease; Drug Evaluation, Preclinical; Female; Mice; Minocycline; Py | 1991 |
Anti-Toxoplasma effects of dapsone alone and combined with pyrimethamine.
Topics: Animals; Cells, Cultured; Dapsone; Drug Combinations; Fibroblasts; Immunoenzyme Techniques; Mice; Mo | 1991 |
Use of mouse macrophage cell lines for in vitro propagation of Toxoplasma gondii RH tachyzoites.
Topics: Animals; Cell Line; Electrophoresis, Polyacrylamide Gel; Kinetics; Macrophages; Mice; Protozoan Prot | 1991 |
Activity of gamma interferon in combination with pyrimethamine or clindamycin in treatment of murine toxoplasmosis.
Topics: Animals; Clindamycin; Drug Combinations; Female; Interferon-gamma; Mice; Pyrimethamine; Recombinant | 1990 |
In vivo assessment of antimicrobial agents against Toxoplasma gondii by quantification of parasites in the blood, lungs, and brain of infected mice.
Topics: Animals; Anti-Infective Agents; Brain; Clindamycin; Female; Kinetics; Lung; Mice; Pyrimethamine; Sul | 1990 |
[Efficacy of treatments in experimental toxoplasmosis].
Topics: Animals; Blood-Retinal Barrier; Clindamycin; Doxycycline; Drug Therapy, Combination; Female; Male; P | 1989 |
Zidovudine antagonizes the action of pyrimethamine in experimental infection with Toxoplasma gondii.
Topics: Animals; Cells, Cultured; Drug Interactions; Female; Fibroblasts; Humans; Male; Mice; Pyrimethamine; | 1989 |
[Surface charged liposomes as drug carriers and in vivo tests of mice infected with toxoplasma].
Topics: Animals; Drug Carriers; Electrochemistry; Liposomes; Mice; Pyrimethamine; Sulfadiazine; Toxoplasmosi | 1989 |
Potent effect of trimetrexate, a lipid-soluble antifolate, on Toxoplasma gondii.
Topics: Animals; Cells, Cultured; Drug Therapy, Combination; Folic Acid Antagonists; Macrophages; Mice; Mice | 1987 |
Chemotherapy of experimental toxoplasmosis with special reference to robenidine.
Topics: Animals; Brain; Drug Administration Schedule; Drug Therapy, Combination; Female; Guanidines; Mice; P | 1988 |
In vivo activity of piritrexim [corrected] against Toxoplasma gondii.
Topics: Animals; Anti-Infective Agents; Drug Combinations; Drug Evaluation, Preclinical; Mice; Pyrimethamine | 1987 |
[Effect of pyrimethamine sulfadoxine (Fansidar) on an avirulent cystogenic strain of Toxoplasma gondii (Prugniaud strain) in white mice].
Topics: Animals; Drug Combinations; Mice; Pyrimethamine; Sulfadoxine; Sulfanilamides; Toxoplasmosis, Animal | 1985 |
Five drug regimens for treatment of acute toxoplasmosis in squirrel monkeys.
Topics: Animals; Clindamycin; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Leuco | 1985 |
[Comparative study on the effect of some clinically used sulfanilamide derivatives against toxoplasmosis in the mouse].
Topics: Aminobenzoates; Animals; Dapsone; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Syn | 1973 |
[Experimental study of the activity of the sulphamethoxypyrazine (Longum equals Kelfizina) with pyrimethamine (Daraprim) on the cysts development phase of Toxoplasma gondii in Mastomys natalensis. Further contribution to experimental chemotherapy of toxop
Topics: Animals; Brain; Drug Therapy, Combination; Female; Male; Pyrimethamine; Rodent Diseases; Rodentia; S | 1974 |
Symptoms, transmission, prevention and treatment of toxoplasmosis.
Topics: Adult; Animals; Cat Diseases; Cats; Child; Dogs; Female; Humans; Infant; Infant, Newborn; Lymph Node | 1973 |
[Experimental studies of the activity of certain drugs on zoites and cyst development of toxoplasma gondii in NMRI mice].
Topics: Animals; Brain; Female; Leucomycins; Mice; Mice, Inbred Strains; Pyrimethamine; Pyrimidines; Sulfame | 1972 |
Human toxoplasmosis: an evaluation of current progress.
Topics: Animals; Antibodies; Cats; Climate; Disease Reservoirs; Dogs; Female; Humans; Infant, Newborn; Pregn | 1972 |
Toxoplasmosis. With comments on risk of infection from cats.
Topics: Animals; Cat Diseases; Cats; Feces; Female; Food Contamination; Humans; Male; Meat; Pregnancy; Pregn | 1972 |
[Action of an association of 2-sulfamido-3-methoxypyazine and 2,4-diamino-p-chlorophenyl-6-ehtylpyrimidine in experimental toxoplasmosis].
Topics: Animals; Mice; Pyrazines; Pyrimethamine; Sulfonamides; Toxoplasmosis, Animal | 1971 |
Toxoplasma gondii life cycle in cats.
Topics: Animals; Antigens; Carrier State; Cat Diseases; Cats; Feces; Intestines; Isospora; Mice; Pyrimethami | 1970 |
[The association of sulfamethoxypyrazine and pyrimethamine in the therapy of experimental toxoplasmosis in mice].
Topics: Aniline Compounds; Animals; Drug Synergism; Male; Mice; Pyrazines; Pyrimethamine; Toxoplasmosis, Ani | 1968 |