Page last updated: 2024-11-03

pyrimethamine and Thrombocytopenia

pyrimethamine has been researched along with Thrombocytopenia in 16 studies

Maloprim: contains above 2 cpds

Thrombocytopenia: A subnormal level of BLOOD PLATELETS.

Research Excerpts

ExcerptRelevanceReference
"Cerebral toxoplasmosis is the most frequent opportunistic infection in patients with acquired immune deficiency syndrome in France."2.67[Primary prophylaxis against cerebral toxoplasmosis. Efficacy of folinic acid in the prevention of hematologic toxicity of pyrimethamine]. ( Barbeau, P; Brossard, G; Leng, B; Neau, D; Pellegrin, JL, 1994)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's1 (6.25)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
CROSBY, WH1
KAUFMAN, RM1
TENPAS, A1
ABRAHAM, JP1
Colebunders, R1
Mathijs, R1
Brossard, G1
Neau, D1
Barbeau, P1
Pellegrin, JL1
Leng, B1
Girdwood, RH1
Koppe, JG1
Pengelly, CD1
Matthews, JI1
Molitor, JT1
Hunt, KK1
Campbell, CH1
Holiday, J1
Biggs, JC1
Backhouse, TC1
Sheehy, TW1
Reba, RC1
Parks, GR1
Gross, R1
Voller, A1
Hawkey, CM1
Richards, WH1
Ridley, DS1
Geils, GF1
Scott, CW1
Baugh, CM1
Kupka, S1
Weirich, J1
Micheels, KH1
Weissbach, G1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Dihydroartemisinin-Piperaquine or Sulphadoxine-Pyrimethamine for the Chemoprevention of Malaria in Children With Sickle Cell Anaemia in Eastern and Southern Africa: a Double Blind Randomised Trial (CHEMCHA)[NCT04844099]Phase 3723 participants (Actual)Interventional2021-04-09Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for pyrimethamine and Thrombocytopenia

ArticleYear
[Primary prophylaxis against cerebral toxoplasmosis. Efficacy of folinic acid in the prevention of hematologic toxicity of pyrimethamine].
    Presse medicale (Paris, France : 1983), 1994, Apr-02, Volume: 23, Issue:13

    Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Blood Cell Count;

1994

Other Studies

15 other studies available for pyrimethamine and Thrombocytopenia

ArticleYear
DRUG-INDUCED THROMBOCYTOPENIA.
    The Medical annals of the District of Columbia, 1964, Volume: 33

    Topics: Acetazolamide; Anticonvulsants; Arsphenamine; Chloramphenicol; Chlorothiazide; Colchicine; Gold; Hyd

1964
HEMATOLOGICAL SIDE-EFFECTS OF PYRIMETHAMINE IN THE TREATMENT OF OCULAR TOXOPLASMOSIS.
    The American journal of the medical sciences, 1965, Volume: 249

    Topics: Anemia; Anemia, Macrocytic; Blood Platelets; Drug Therapy; Folic Acid; Hemoglobinometry; Humans; Leu

1965
Ocular toxoplasmosis treated with pyrimethamine.
    American journal of ophthalmology, 1982, Volume: 93, Issue:3

    Topics: Adult; Female; Humans; Leucovorin; Leukopenia; Pyrimethamine; Thrombocytopenia; Toxoplasmosis, Ocula

1982
The nature of possible adverse reactions to co-trimoxazole.
    Scandinavian journal of infectious diseases. Supplementum, 1976, Issue:8

    Topics: Aminopterin; Anemia, Megaloblastic; Chemical Phenomena; Chemistry; Drug Combinations; Folic Acid; Hu

1976
[Letter: Significance of Toxoplasma infections for public health].
    Nederlands tijdschrift voor geneeskunde, 1975, Sep-20, Volume: 119, Issue:38

    Topics: Eye Manifestations; Humans; Immunoglobulin M; Infant, Newborn; Leucomycins; Pyrimethamine; Sulfadiaz

1975
Reduction of haematocrit and red-blood-cell volume in patients with polycythaemia secondary to hypoxic lung disease by dapsone and pyrimethamine.
    Lancet (London, England), 1966, Dec-24, Volume: 2, Issue:7478

    Topics: Dapsone; Erythropoiesis; Hematocrit; Humans; Lung Diseases; Polycythemia; Pyrimethamine; Thrombocyto

1966
Pyrimethamine-induced leukopenia and thrombocytopenia in a patient with malaria and tropical sprue: case report.
    Military medicine, 1973, Volume: 138, Issue:5

    Topics: Adult; Humans; Leukopenia; Malaria; Male; Pyrimethamine; Sprue, Tropical; Thrombocytopenia

1973
Chloroquine-resistant Falciparum malaria acquired in Vietnam.
    The Medical journal of Australia, 1973, Oct-13, Volume: 2, Issue:15

    Topics: Acute Kidney Injury; Adolescent; Adult; Blood Cell Count; Chloroquine; Dapsone; Drug Resistance, Mic

1973
Combined pyrimethamine-quinine therapy for chloroquine-resistant P. falciparum infections.
    Southern medical journal, 1969, Volume: 62, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Anemia, Hemolytic; Chloroquine; Clinical Laboratory Techniques;

1969
[The therapy of blood platelet disorders].
    Hamatologie und Bluttransfusion, 1969, Volume: 6

    Topics: Blood Platelet Disorders; Bone Marrow Transplantation; Corticosterone; Hemostatics; Humans; Immunosu

1969
Human malaria (Plasmodium falciparum) in owl monkeys (Aotus trivirgatus).
    The Journal of tropical medicine and hygiene, 1969, Volume: 72, Issue:7

    Topics: Anemia; Animals; Antimalarials; Blood Coagulation; Haplorhini; Malaria; Myocardium; Plasmodium falci

1969
Treatment of meningeal leukemia with pyrimethamine.
    Blood, 1971, Volume: 38, Issue:2

    Topics: Adult; Brain Diseases; Folic Acid; Hallucinations; Humans; Leukemia, Myeloid, Acute; Male; Meninges;

1971
[Stages in the prophylaxis of toxoplasmosis].
    Zentralblatt fur Gynakologie, 1970, Dec-19, Volume: 92, Issue:51

    Topics: Adult; Bone Marrow; Bone Marrow Diseases; Female; Humans; Leucovorin; Pregnancy; Pregnancy Complicat

1970
[Demonstration of the toxic effect of daraprim on hematopoiesis in a re-exposure study].
    Das Deutsche Gesundheitswesen, 1969, Dec-11, Volume: 24, Issue:50

    Topics: Adolescent; Female; Hematopoiesis; Humans; Methemoglobin; Pyrimethamine; Sulfamethazine; Thrombocyto

1969
[Effects of combined treatment of infantile toxoplasmosis with pyrimethamine (daraprim) and sulfonamides on the blood and bone marrow].
    Zeitschrift fur arztliche Fortbildung, 1965, Jan-01, Volume: 59, Issue:1

    Topics: Agranulocytosis; Anemia, Macrocytic; Drug Synergism; Folic Acid Antagonists; Humans; Infant; Infant,

1965