pyrimethamine has been researched along with Recrudescence in 118 studies
Maloprim: contains above 2 cpds
| Excerpt | Relevance | Reference |
|---|---|---|
| "the efficacy of fixed co-formulated (f) artesunate-sulfamethoxypyrazine-pyrimethamine (AS+SMP f) administered at time intervals of 12 hours for a 24-hour therapy was compared with the efficacy of the same drug given as a loose combination (AS+SMP l) with a dose interval of 24 hours for 3 days for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan." | 9.12 | A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan. ( Adam, I; Alifrangis, M; Elmardi, KA; Khalil, IF; Magzoub, M; Osman, ME, 2006) |
| "In an open, randomized, clinical trial, conducted in New Halfa, eastern Sudan, in September-October 2004, the efficacies and adverse effects of artesunate plus sulfadoxine-pyrimethamine (SP), in the treatment of uncomplicated, Plasmodium falciparum malaria, were compared with those of SP alone." | 9.11 | A comparison of the efficacy of artesunate plus sulfadoxine-pyrimethamine with that of sulfadoxine-pyrimethamine alone, in the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan. ( A-Elbasit, IE; Adam, I; Elbashir, MI; Idris, SM; Malik, EM, 2005) |
| "Fifty-nine patients with active ocular toxoplasmosis were randomly assigned to 2 treatment groups: 29 were treated with pyrimethamine/sulfadiazine, and 30 patients received trimethoprim/sulfamethoxazole." | 9.11 | Prospective randomized trial of trimethoprim/sulfamethoxazole versus pyrimethamine and sulfadiazine in the treatment of ocular toxoplasmosis. ( Anisian, A; Behboudi, H; Dehghan, MH; Ghajarnia, M; Peyman, GA; Sadoughi, MM; Soheilian, M; Yazdani, S, 2005) |
| "A prospective clinical trial was carried out to determine in vivo efficacy of sulfadoxine/pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in children in New Halfa." | 9.11 | Efficacy of sulfadoxin pyrimethamine for uncomplicated Plasmodium falciparum malaria in a small sample of Sudanese children. ( A/elbasit, IA; Adam, I; Elbashir, MI; Ibrahim, MH, 2004) |
| "The efficacy and kinetics of the combination chloroquine plus sulfadoxine-pyrimethamine (CQ + SP), given sequentially and simultaneously, were investigated in 32 patients with acute uncomplicated Plasmodium falciparum malaria in Palawan Island, the Philippines." | 9.10 | Pharmacokinetics of sequential and simultaneous treatment with the combination chloroquine and sulfadoxine-pyrimethamine in acute uncomplicated Plasmodium falciparum malaria in the Philippines. ( Bustos, DG; Diquet, B; Gay, F; Laracas, CJ; Lazaro, JE; Pottier, A; Traore, B, 2002) |
| " In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)." | 9.10 | A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002) |
| "To evaluate the efficacy and tolerance of atovaquone used as long-term maintenance therapy in patients with toxoplasmic encephalitis and intolerant of conventional anti-Toxoplasma therapies." | 9.08 | Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group. ( Gourdon, D; Katlama, C; Lapierre, D; Mouthon, B; Rousseau, F, 1996) |
| "Mefloquine is the treatment of choice for uncomplicated multiresistant falciparum malaria, and in combination with sulphadoxine and pyrimethamine (MSP) at a single dose of 15/30/1." | 9.07 | Mefloquine-resistant falciparum malaria on the Thai-Burmese border. ( Chongsuphajaisiddhi, T; Edstein, M; Luxemburger, C; Nosten, F; Phaipun, L; ter Kuile, F; Thew, KL; Webster, HK; White, NJ, 1991) |
| "Despite widespread parasite resistance to sulphadoxine-pyrimethamine (SP) its use for intermittent preventative treatment during pregnancy remains the policy in Benin and throughout most of sub-Saharan Africa." | 7.79 | High rates of parasite recrudescence following intermittent preventive treatment with sulphadoxine-pyrimethamine during pregnancy in Benin. ( Alifrangis, M; De Tove, YS; Deloron, P; Doritchamou, J; Luty, AJ; Massougbodji, A; Moussiliou, A; Ndam, NT, 2013) |
| "A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines." | 7.73 | Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis. ( Boyer, K; Jalbrzikowski, J; Khan, AR; Latkany, P; McLeod, R; Noble, GA, 2006) |
| "The efficacy and safety of 25 mg pyrimethamine plus 500 mg sulfadoxine given twice a week in preventing relapses of AIDS-related toxoplasmic encephalitis was evaluated in an open study." | 7.68 | Efficacy of pyrimethamine/sulfadoxine in the prevention of toxoplasmic encephalitis relapses and Pneumocystis carinii pneumonia in HIV-infected patients. ( Bergmann, F; Gottschalk, HJ; Grünewald, T; Pohle, HD; Ruf, B; Schüler-Maué, W; Schürmann, D; Witt, H, 1993) |
| " The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P." | 6.71 | A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003) |
| "Recurrences were rarely observed in the two groups: respectively 8% and 6% of cases." | 6.68 | [Value of clindamycin in the treatment of ocular toxoplasmosis]. ( Ayed, S; Azaiez, A; Bouguila, H; Daghfous, F; Jeddi, A; Kaoueche, M; Malouche, S, 1997) |
| "After 14 months' follow up, recurrences of ocular toxoplasmosis developed in both groups, 21% with clindamycin and 36% with P + S, respectively (NS)." | 6.66 | [Presumed toxoplasmic chorioretinitis: comparative study of treatment with pyrimethamine and sulfadiazine or clindamycin]. ( Colin, J; Harie, JC, 1989) |
| "the efficacy of fixed co-formulated (f) artesunate-sulfamethoxypyrazine-pyrimethamine (AS+SMP f) administered at time intervals of 12 hours for a 24-hour therapy was compared with the efficacy of the same drug given as a loose combination (AS+SMP l) with a dose interval of 24 hours for 3 days for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan." | 5.12 | A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan. ( Adam, I; Alifrangis, M; Elmardi, KA; Khalil, IF; Magzoub, M; Osman, ME, 2006) |
| " We recommend the use of artemisinin-based combination therapy as first-line treatment for uncomplicated Plasmodium falciparum malaria in Koumantou." | 5.12 | Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali. ( de Radiguès, X; Diallo, KI; Diallo, M; Djimdé, A; Doumbo, O; Guthmann, JP; Maiga, H; Ngwakum, PA; Sacko, M, 2006) |
| "A prospective clinical trial was carried out to determine in vivo efficacy of sulfadoxine/pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in children in New Halfa." | 5.11 | Efficacy of sulfadoxin pyrimethamine for uncomplicated Plasmodium falciparum malaria in a small sample of Sudanese children. ( A/elbasit, IA; Adam, I; Elbashir, MI; Ibrahim, MH, 2004) |
| "In an open, randomized, clinical trial, conducted in New Halfa, eastern Sudan, in September-October 2004, the efficacies and adverse effects of artesunate plus sulfadoxine-pyrimethamine (SP), in the treatment of uncomplicated, Plasmodium falciparum malaria, were compared with those of SP alone." | 5.11 | A comparison of the efficacy of artesunate plus sulfadoxine-pyrimethamine with that of sulfadoxine-pyrimethamine alone, in the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan. ( A-Elbasit, IE; Adam, I; Elbashir, MI; Idris, SM; Malik, EM, 2005) |
| "Fifty-nine patients with active ocular toxoplasmosis were randomly assigned to 2 treatment groups: 29 were treated with pyrimethamine/sulfadiazine, and 30 patients received trimethoprim/sulfamethoxazole." | 5.11 | Prospective randomized trial of trimethoprim/sulfamethoxazole versus pyrimethamine and sulfadiazine in the treatment of ocular toxoplasmosis. ( Anisian, A; Behboudi, H; Dehghan, MH; Ghajarnia, M; Peyman, GA; Sadoughi, MM; Soheilian, M; Yazdani, S, 2005) |
| "The efficacy and kinetics of the combination chloroquine plus sulfadoxine-pyrimethamine (CQ + SP), given sequentially and simultaneously, were investigated in 32 patients with acute uncomplicated Plasmodium falciparum malaria in Palawan Island, the Philippines." | 5.10 | Pharmacokinetics of sequential and simultaneous treatment with the combination chloroquine and sulfadoxine-pyrimethamine in acute uncomplicated Plasmodium falciparum malaria in the Philippines. ( Bustos, DG; Diquet, B; Gay, F; Laracas, CJ; Lazaro, JE; Pottier, A; Traore, B, 2002) |
| " In the present study, the efficacies of chloroquine (CQ) or amodiaquine (AQ) in the oral treatment of acute, symptomatic, uncomplicated, Plasmodium falciparum malaria were compared with those of oral treatments with the combination of CQ or AQ with pyrimethamine-sulfadoxine (PS)." | 5.10 | A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2002) |
| "To evaluate the efficacy and tolerance of atovaquone used as long-term maintenance therapy in patients with toxoplasmic encephalitis and intolerant of conventional anti-Toxoplasma therapies." | 5.08 | Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group. ( Gourdon, D; Katlama, C; Lapierre, D; Mouthon, B; Rousseau, F, 1996) |
| "Mefloquine is the treatment of choice for uncomplicated multiresistant falciparum malaria, and in combination with sulphadoxine and pyrimethamine (MSP) at a single dose of 15/30/1." | 5.07 | Mefloquine-resistant falciparum malaria on the Thai-Burmese border. ( Chongsuphajaisiddhi, T; Edstein, M; Luxemburger, C; Nosten, F; Phaipun, L; ter Kuile, F; Thew, KL; Webster, HK; White, NJ, 1991) |
| "Despite widespread parasite resistance to sulphadoxine-pyrimethamine (SP) its use for intermittent preventative treatment during pregnancy remains the policy in Benin and throughout most of sub-Saharan Africa." | 3.79 | High rates of parasite recrudescence following intermittent preventive treatment with sulphadoxine-pyrimethamine during pregnancy in Benin. ( Alifrangis, M; De Tove, YS; Deloron, P; Doritchamou, J; Luty, AJ; Massougbodji, A; Moussiliou, A; Ndam, NT, 2013) |
| "Atypical, 100 microm to 150 microm, greyish deposits appeared along retinal arteries and veins as well as on the vitreoretinal interface in the macula of a 44-year-old Caucasian woman while she was being treated for recurrent toxoplasmic chorioretinitis with antiparasitic drugs and subconjunctival injection of betamethasone." | 3.74 | Atypical spherical deposition on vitreoretinal interface associated with toxoplasmic chorioretinitis. ( De Potter, P; Guagnini, AP; Kozyreff, A; Levecq, L, 2007) |
| "A 7-year-old with congenital toxoplasmosis who took pyrimethamine and sulfadiazine for reactivated chorioretinitis developed fever, severe cutaneous involvement, swelling, abdominal pain and transaminitis, persisting weeks after withholding medicines." | 3.73 | Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis. ( Boyer, K; Jalbrzikowski, J; Khan, AR; Latkany, P; McLeod, R; Noble, GA, 2006) |
| "Febrile adults with Plasmodium falciparum parasitemia were treated with sulfadoxine-pyrimethamine and were monitored for 28 days." | 3.73 | HIV immunosuppression and antimalarial efficacy: sulfadoxine-pyrimethamine for the treatment of uncomplicated malaria in HIV-infected adults in Siaya, Kenya. ( Bloland, PB; Hamel, MJ; Kain, KC; Obonyo, CO; Shah, SN; Slutsker, L; Smith, EE, 2006) |
| "A pyrimethamine-resistant line of Plasmodium berghei was derived by treating infected mice with high doses of pyrimethamine and selecting for recrudescence." | 3.69 | Effect of pyrimethamine resistance on sporogony in a Plasmodium berghei/Anopheles stephensi model. ( Lanners, HN; Lowrie, RC; Shinondo, CJ; Wiser, MF, 1994) |
| " 1, 1973, and May 30, 1989, 36 patients (37 eyes) with ocular toxoplasmosis seen at a uveitis clinic received quadruple therapy (pyrimethamine, trisulfapyrimidines, clindamycin and prednisone)." | 3.68 | Quadruple therapy for ocular toxoplasmosis. ( Lam, S; Tessler, HH, 1993) |
| "The efficacy and safety of 25 mg pyrimethamine plus 500 mg sulfadoxine given twice a week in preventing relapses of AIDS-related toxoplasmic encephalitis was evaluated in an open study." | 3.68 | Efficacy of pyrimethamine/sulfadoxine in the prevention of toxoplasmic encephalitis relapses and Pneumocystis carinii pneumonia in HIV-infected patients. ( Bergmann, F; Gottschalk, HJ; Grünewald, T; Pohle, HD; Ruf, B; Schüler-Maué, W; Schürmann, D; Witt, H, 1993) |
| " We treated 23 patients with acute toxoplasma chorioretinitis with sulfonamides, pyrimethamine and corticosteroids for a period of 4 weeks." | 3.68 | [Treatment of toxoplasmosis. The treatment of toxoplasmic chorioretinitis]. ( Aspiotis, M; Petroutsos, G; Psilas, K, 1990) |
| " The goal of the present paper was to study the recurrence rate of ocular toxoplasmosis during a four years period following a Pyrimethamine-sulfadiazine therapy." | 3.67 | [Efficacy of specific chemotherapy in the prevention of recurrences of toxoplasmic chorioretinitis during the 4 years following the treatment]. ( Bloch-Michel, E; Timsit, JC, 1987) |
| "The antiplasmodial effect of a single dose treatment with a sulfadoxine/pyrimethamine combination as compared to a sulfalene/pyrimethamine combination against falciparum malaria was assessed in semi-immune populations in Burma in early 1980." | 3.67 | Comparative drug trial of a sulfadoxine/pyrimethamine and a sulfalene/pyrimethamine combination against Plasmodium falciparum infections in semi-immune populations of Burma. ( Tin, F, 1984) |
| " In case of maternal contamination after 33 weeks of pregnancy, pyrimethamine-sulfadiazine combination should be used in spite of its potential toxicity." | 3.67 | New perspectives in the chemoprophylaxis of toxoplasmosis. ( Garin, JP; Piens, MA, 1989) |
| "The corresponding risks of recurrence were 13." | 2.87 | Low risk of recurrence following artesunate-Sulphadoxine-pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan. ( Abdelbagi, H; Basheir, HM; Boshara, SA; Chen, I; Elobied, ME; Elsafi, HMH; Gosling, R; Gumaa, SA; Hamid, MMA; Hamid, T; Ley, B; Mahgoub, NS; Marfurt, J; Price, RN; Thriemer, K, 2018) |
| "Nearly all recurrences were due to new infections." | 2.73 | Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial. ( Dokomajilar, C; Dorsey, G; Guiguemde, RT; Ouedraogo, JB; Rosenthal, PJ; Rouamba, N; Tinto, H; Zongo, I, 2007) |
| " The findings indicate that - at least at the dosing regimen used in the present study and among children with acute, uncomplicated, P." | 2.71 | A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children. ( Sowunmi, A, 2003) |
| "Recurrences were rarely observed in the two groups: respectively 8% and 6% of cases." | 2.68 | [Value of clindamycin in the treatment of ocular toxoplasmosis]. ( Ayed, S; Azaiez, A; Bouguila, H; Daghfous, F; Jeddi, A; Kaoueche, M; Malouche, S, 1997) |
| "The mean recurrence rate after three years of follow-up was 49% for all patients (60 of 122 patients), with no differences between treated and untreated patients (P = ." | 2.67 | Therapy for ocular toxoplasmosis. ( Baarsma, GS; Boen-Tan, TN; Brinkman, CJ; Buitenhuis, HJ; de Jong, PT; Klaassen-Broekema, N; Meenken, C; Rothova, A; Schweitzer, CM; Timmerman, Z, 1993) |
| "Congenital ocular toxoplasmosis with recurrences must be treated by Spiramycin destroys trophozoites when they escape from the true cysts." | 2.66 | [Treatment of recurrent congenital ocular toxoplasmosis. Our initial experience with Fansidar]. ( Comte, P; Le Bras, M; Verin, P, 1989) |
| "After 14 months' follow up, recurrences of ocular toxoplasmosis developed in both groups, 21% with clindamycin and 36% with P + S, respectively (NS)." | 2.66 | [Presumed toxoplasmic chorioretinitis: comparative study of treatment with pyrimethamine and sulfadiazine or clindamycin]. ( Colin, J; Harie, JC, 1989) |
| " gondii pneumonia should use the synergistic combination of pyrimethamine and a sulfa-based antibiotic, optimal prophylactic antibiotic combinations and dosing schedules for recurrent infection are still being investigated." | 2.40 | Pulmonary toxoplasmosis. ( Campagna, AC, 1997) |
| "Ocular toxoplasmosis is the leading cause of posterior uveitis worldwide." | 1.62 | Clinical manifestations and visual outcomes associated with ocular toxoplasmosis in a Brazilian population. ( Araújo, M; Arruda, S; Belfort, R; Furtado, JM; Garcia, DM; Moreto, R; Rodrigues, MW; Simões, M; Smith, JR; Vieira, BR, 2021) |
| "Following A-SP the recurrence rates were low and recurrence-free periods tended to be longer." | 1.43 | The Impact of Short-Term, Intensive Antifolate Treatment (with Pyrimethamine and Sulfadoxine) and Antibiotics Followed by Long-Term, Secondary Antifolate Prophylaxis on the Rate of Toxoplasmic Retinochoroiditis Recurrence. ( Basiak, W; Borkowski, PK; Brydak-Godowska, J; Kajfasz, P; Olszyńska-Krowicka, M; Rabczenko, D; Świtaj, K; Żarnowska-Prymek, H, 2016) |
| "After 5 months, new seizures were reported and a diagnosis of epilepsy was done." | 1.43 | Recurrent seizures during acute acquired toxoplasmosis in an immunocompetent traveller returning from Africa. ( Bassetti, M; Beltrame, A; Buonfrate, D; Crichiutti, G; Meroni, V; Venturini, S, 2016) |
| "Genotyping confirmed that recrudescence after malaria treatment occurred in 7 (21%) out of 33 pregnant women with consecutive episodes during the same pregnancy (time range between recrudescent episodes: 14 to 187 days)." | 1.35 | Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women. ( Alonso, PL; Aponte, JJ; Bardají, A; Cisteró, P; Mandomando, I; Mayor, A; Menéndez, C; Puyol, L; Sanz, S; Serra-Casas, E; Sigauque, B, 2009) |
| " americanum, treatment with trimethoprim-sulfadiazine, clindamycin, and pyrimethamine followed by long-term administration of decoquinate resulted in extended survival times and excellent quality of life." | 1.31 | Treatment of dogs infected with Hepatozoon americanum: 53 cases (1989-1998). ( Blagburn, BL; Dillon, AR; Kane, CW; Lindsay, DS; Macintire, DK; Vincent-Johnson, NA, 2001) |
| "Recrudescences were simulated in vitro with drug treatment to examine how drug-sensitive parasites survive the treatment." | 1.31 | Malaria parasites giving rise to recrudescence in vitro. ( Ito, Y; Kanbara, H; Maoka, T; Nakazawa, S; Uemura, H, 2002) |
| "Both patients had a recurrence on the peripheral aspect of scars from previous retinochoroiditis and were treated with pyrimethamine (50 mg/day) and sulfadiazine (4 g/day) for seven weeks." | 1.30 | Recurrent toxoplasmic retinochoroiditis. Significance of perilesional satellite dark dots seen by indocyanine green angiography. ( Auer, C; Bernasconi, O; Herbort, CP, 1997) |
| "Chloroquine was prescribed at 25 mg/kg for 3 days in febrile patients with uncomplicated P." | 1.30 | [Chloroquine sensitivity of Plasmodium falciparum at the Gamkalley Clinic and the Nigerian armed forces PMI (Niamey, Niger)]. ( Ali, I; Bendavid, C; Condomines, P; Crassard, N; Djermakoye, F; Faugère, B; Parola, P, 1999) |
| "Primaquine has been found adequate to prevent relapse in more than 90% vivax cases, while efficacy of chloroquine-pyrimethamine and chloroquine alone was almost comparable." | 1.29 | Studies on Plasmodium vivax relapse pattern in Kheda district, Gujarat. ( Bhatt, RM; Sharma, SK; Sharma, VP; Srivastava, HC, 1996) |
| "Treatment with pyrimethamine plus sulfadiazine produced clinical cures in 100% of the infected mice 1 month after infection." | 1.29 | A clinical-parasitological monotherapy cure in the treatment of experimental infection by a highly virulent strain of Toxoplasma gondii. ( Arribas, JR; de Diego, JA; Penin, P; Vázquez, E; Vázquez, JJ, 1996) |
| "A pregnant woman was diagnosed with central nervous system toxoplasmosis and human immunodeficiency virus infection." | 1.29 | Normal fetal outcome in a pregnancy with central nervous system toxoplasmosis and human immunodeficiency virus infection. A case report. ( Brown, GM; Hedriana, HL; Mitchell, JL; Williams, SB, 1993) |
| "The basis of recrudescence, the reappearance of malaria parasites after chemotherapy or after failure of immune suppressions of the parasites, was studied in cultures of Plasmodium falciparum." | 1.29 | Plasmodium falciparum: recrudescence of parasites in culture. ( Aikawa, M; Kanbara, H; Nakazawa, S, 1995) |
| "Many children with congenital toxoplasmosis have substantial retinal damage at birth and consequent loss of vision." | 1.29 | Eye manifestations of congenital toxoplasmosis. ( Boyer, KM; Holfels, E; Hopkins, J; Luciano, R; Mack, D; McLeod, R; Meier, P; Mets, MB; Patel, D; Remington, JS; Roizen, N; Stein, L; Stein, M; Swisher, CN; Withers, S, 1996) |
| "Ten (91%) of these 11 patients with recurrence showed focal persistent enhancement after the initial treatment of toxoplasmosis abscess." | 1.29 | Persistent enhancement after treatment for cerebral toxoplasmosis in patients with AIDS: predictive value for subsequent recurrence. ( Benmelha, Z; Bouvet, E; Casalino, E; Laissy, JP; Lariven, S; Parlier, C; Servois, V; Sibert, A; Soyer, P; Vachon, F, 1994) |
| "Fever was the only clinical manifestation attributable to parasitemia and only when the parasite density was > or = 5000/microL." | 1.29 | Impact of transmission intensity and age on Plasmodium falciparum density and associated fever: implications for malaria vaccine trial design. ( Bales, JD; Beadle, C; Beier, JC; Chumo, DK; Hoffman, SL; McElroy, PD; Oloo, AJ; Onyango, FK; Oster, CN; Sherwood, JA, 1995) |
| "No relapse was observed in those receiving P/S, but 40% of those treated with P/C relapsed." | 1.28 | [Encephalic toxoplasmosis in patients with the acquired immunodeficiency syndrome. A clinico-radiological study and the therapeutic results in 78 cases]. ( Alvarez, R; Gatell, JM; González-Clemente, JM; Graus, F; Guelar, A; Jiménez de Anta, MT; Mallolas, J; Mercader, JM; Miró, JM; Pedrol, E, 1990) |
| "Pneumocystis carinii pneumonia is an important infection in patients infected with the human immunodeficiency virus." | 1.28 | Experience with pneumocystis carinii pneumonia in patients with AIDS. ( Davis, R; Ellis-Pegler, RB; Ingram, RJ, 1989) |
| "In 33 consecutive AIDS patients with a first episode of Pneumocystis carinii pneumonia (PCP) we evaluated treatment, outcome, recurrence rate and pyrimethamine as chemoprophylaxis in a 1-year follow-up." | 1.28 | Pneumocystis carinii pneumonia in Stockholm, Sweden: treatment, outcome, one-year-follow-up and pyrimethamine prophylaxis. ( Bergdahl, S; Julander, I; Lidman, C; Lundbergh, P; Ortqvist, A, 1989) |
| "There was the recrudescence of falciparum malaria at 8." | 1.27 | Clinical evaluation of antimalarial regimens in Japan. ( Hioki, A; Ishizaki, T; Nakabayashi, T; Ohtomo, H; Tanabe, K, 1987) |
| " The usefulness of high dosage heparin in the treatment of the subacute form of disseminated intravascualr coagulation is illustrated in the first admission." | 1.25 | A case of recurrent subacute disseminated intravascular coagulation associated with malarial prophylaxis. ( Gon, F; Reid, FP, 1975) |
| " Increasing the drug dosage does not overcome the resistance." | 1.24 | The development of pyrimethamine resistance by Plasmodium falciparum. ( BURGESS, RW; YOUNG, MD, 1959) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 41 (34.75) | 18.7374 |
| 1990's | 28 (23.73) | 18.2507 |
| 2000's | 36 (30.51) | 29.6817 |
| 2010's | 10 (8.47) | 24.3611 |
| 2020's | 3 (2.54) | 2.80 |
| Authors | Studies |
|---|---|
| Joste, V | 1 |
| Guillochon, E | 1 |
| Clain, J | 1 |
| Coppée, R | 1 |
| Houzé, S | 1 |
| Crider, K | 1 |
| Williams, J | 1 |
| Qi, YP | 1 |
| Gutman, J | 1 |
| Yeung, L | 1 |
| Mai, C | 1 |
| Finkelstain, J | 1 |
| Mehta, S | 1 |
| Pons-Duran, C | 1 |
| Menéndez, C | 2 |
| Moraleda, C | 1 |
| Rogers, L | 1 |
| Daniels, K | 1 |
| Green, P | 1 |
| Arruda, S | 1 |
| Vieira, BR | 1 |
| Garcia, DM | 1 |
| Araújo, M | 1 |
| Simões, M | 1 |
| Moreto, R | 1 |
| Rodrigues, MW | 1 |
| Belfort, R | 1 |
| Smith, JR | 1 |
| Furtado, JM | 1 |
| Hamid, MMA | 1 |
| Thriemer, K | 1 |
| Elobied, ME | 1 |
| Mahgoub, NS | 1 |
| Boshara, SA | 1 |
| Elsafi, HMH | 1 |
| Gumaa, SA | 1 |
| Hamid, T | 1 |
| Abdelbagi, H | 1 |
| Basheir, HM | 1 |
| Marfurt, J | 1 |
| Chen, I | 1 |
| Gosling, R | 1 |
| Price, RN | 2 |
| Ley, B | 1 |
| Moussiliou, A | 1 |
| De Tove, YS | 1 |
| Doritchamou, J | 1 |
| Luty, AJ | 1 |
| Massougbodji, A | 1 |
| Alifrangis, M | 2 |
| Deloron, P | 1 |
| Ndam, NT | 1 |
| Beltrame, A | 1 |
| Venturini, S | 1 |
| Crichiutti, G | 1 |
| Meroni, V | 1 |
| Buonfrate, D | 1 |
| Bassetti, M | 1 |
| Pradhan, E | 1 |
| Bhandari, S | 1 |
| Gilbert, RE | 1 |
| Stanford, M | 1 |
| Borkowski, PK | 1 |
| Brydak-Godowska, J | 1 |
| Basiak, W | 1 |
| Świtaj, K | 1 |
| Żarnowska-Prymek, H | 1 |
| Olszyńska-Krowicka, M | 1 |
| Kajfasz, P | 1 |
| Rabczenko, D | 1 |
| Connolly, MP | 1 |
| Goodwin, E | 1 |
| Schey, C | 1 |
| Zummo, J | 1 |
| Karunajeewa, HA | 1 |
| Mueller, I | 1 |
| Senn, M | 1 |
| Lin, E | 1 |
| Law, I | 1 |
| Gomorrai, PS | 1 |
| Oa, O | 1 |
| Griffin, S | 1 |
| Kotab, K | 1 |
| Suano, P | 1 |
| Tarongka, N | 1 |
| Ura, A | 1 |
| Lautu, D | 1 |
| Page-Sharp, M | 1 |
| Wong, R | 1 |
| Salman, S | 1 |
| Siba, P | 1 |
| Ilett, KF | 1 |
| Davis, TM | 1 |
| Mayor, A | 1 |
| Serra-Casas, E | 1 |
| Bardají, A | 1 |
| Sanz, S | 1 |
| Puyol, L | 1 |
| Cisteró, P | 1 |
| Sigauque, B | 1 |
| Mandomando, I | 1 |
| Aponte, JJ | 1 |
| Alonso, PL | 1 |
| Somé, AF | 1 |
| Séré, YY | 1 |
| Dokomajilar, C | 3 |
| Zongo, I | 3 |
| Rouamba, N | 2 |
| Greenhouse, B | 1 |
| Ouédraogo, JB | 3 |
| Rosenthal, PJ | 4 |
| Ouédraogo, A | 1 |
| Tiono, AB | 1 |
| Diarra, A | 1 |
| Nébié, IO | 1 |
| Konaté, AT | 1 |
| Sirima, SB | 1 |
| Shaukat, AM | 1 |
| Gilliams, EA | 1 |
| Kenefic, LJ | 1 |
| Laurens, MB | 1 |
| Dzinjalamala, FK | 1 |
| Nyirenda, OM | 1 |
| Thesing, PC | 1 |
| Jacob, CG | 1 |
| Molyneux, ME | 2 |
| Taylor, TE | 2 |
| Plowe, CV | 2 |
| Laufer, MK | 1 |
| Sutanto, I | 1 |
| Suprianto, S | 1 |
| Widiaty, A | 1 |
| Ruckert, P | 1 |
| von Bethmann, A | 1 |
| de Monbrison, F | 1 |
| Picot, S | 1 |
| Laihad, F | 2 |
| Baird, JK | 1 |
| Sulo, J | 1 |
| Chimpeni, P | 1 |
| Hatcher, J | 1 |
| Kublin, JG | 1 |
| Marsh, K | 1 |
| Watkins, WM | 2 |
| Winstanley, PA | 1 |
| Jongwutiwes, S | 1 |
| Sampatanukul, P | 1 |
| Putaporntip, C | 1 |
| Cattamanchi, A | 1 |
| Kyabayinze, D | 1 |
| Hubbard, A | 1 |
| Dorsey, G | 3 |
| Sowunmi, A | 4 |
| Fateye, BA | 2 |
| BURGESS, RW | 1 |
| YOUNG, MD | 2 |
| CANAMUCIO, CJ | 1 |
| HALLETT, JW | 1 |
| LEOPOLD, IH | 1 |
| Gatton, ML | 1 |
| Martin, LB | 1 |
| Cheng, Q | 1 |
| Smithuis, F | 1 |
| Shahmanesh, M | 1 |
| Kyaw, MK | 1 |
| Savran, O | 1 |
| Lwin, S | 1 |
| White, NJ | 2 |
| Oh, J | 1 |
| Huh, K | 1 |
| Kim, SW | 1 |
| Omar, SA | 1 |
| Mens, PF | 1 |
| Schoone, GJ | 1 |
| Yusuf, A | 1 |
| Mwangi, J | 1 |
| Kaniaru, S | 1 |
| Omer, GA | 1 |
| Schallig, HD | 1 |
| Adam, I | 3 |
| A-Elbasit, IE | 1 |
| Idris, SM | 1 |
| Malik, EM | 1 |
| Elbashir, MI | 2 |
| Bachmeyer, C | 1 |
| Mouchnino, G | 1 |
| Thulliez, P | 1 |
| Blum, L | 1 |
| Soheilian, M | 1 |
| Sadoughi, MM | 1 |
| Ghajarnia, M | 1 |
| Dehghan, MH | 1 |
| Yazdani, S | 1 |
| Behboudi, H | 1 |
| Anisian, A | 1 |
| Peyman, GA | 1 |
| Ibrahim, MH | 1 |
| A/elbasit, IA | 1 |
| McLeod, R | 4 |
| Khan, AR | 1 |
| Noble, GA | 1 |
| Latkany, P | 2 |
| Jalbrzikowski, J | 2 |
| Boyer, K | 3 |
| Guagnini, AP | 1 |
| De Potter, P | 1 |
| Levecq, L | 1 |
| Kozyreff, A | 1 |
| de Radiguès, X | 1 |
| Diallo, KI | 1 |
| Diallo, M | 1 |
| Ngwakum, PA | 1 |
| Maiga, H | 1 |
| Djimdé, A | 1 |
| Sacko, M | 1 |
| Doumbo, O | 1 |
| Guthmann, JP | 2 |
| Lankoande, ZM | 1 |
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| Brockman, A | 1 |
| Edstein, MD | 1 |
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| Smith, EE | 1 |
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| Bloland, PB | 1 |
| Slutsker, L | 1 |
| Hamel, MJ | 1 |
| Martensson, A | 1 |
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| Wiklund, L | 1 |
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| Farnert, A | 1 |
| Bjorkman, A | 1 |
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| Tinto, H | 1 |
| Guiguemde, RT | 1 |
| Mugittu, K | 1 |
| Priotto, G | 1 |
| Kiguli, J | 1 |
| Adjuik, M | 1 |
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| Beck, HP | 1 |
| Mshinda, H | 1 |
| Olliaro, PL | 1 |
| Taylor, WR | 1 |
| Phan, L | 1 |
| Kasza, K | 1 |
| Noble, AG | 1 |
| Kuo, A | 1 |
| Mieler, W | 1 |
| Meyers, S | 2 |
| Rabiah, P | 2 |
| Swisher, C | 2 |
| Mets, M | 2 |
| Roizen, N | 3 |
| Cezar, S | 1 |
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| Meier, P | 3 |
| Sixsmith, DG | 1 |
| Spencer, HC | 1 |
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| Verin, P | 2 |
| Le Rebeller, MJ | 1 |
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| Beadle, C | 1 |
| McElroy, PD | 1 |
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| Servois, V | 1 |
| Casalino, E | 1 |
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| Katlama, C | 2 |
| Leport, C | 2 |
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| Lacassin, F | 1 |
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| de Jong, PT | 1 |
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| Schweitzer, CM | 1 |
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| Tessler, HH | 1 |
| Nakazawa, S | 2 |
| Kanbara, H | 2 |
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| Luciano, R | 1 |
| Patel, D | 2 |
| Remington, JS | 2 |
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| Macintire, DK | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Study to Assess Current Standard Malaria Treatment Guidelines and Evaluate Recently Developed G6PD Diagnostic Tools in the Republic of the Sudan[NCT02592408] | Phase 4 | 320 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| Influence of Trimethoprim-sulfamethoxazole for the Recurrence of Retinochoroiditis Toxoplasma Gondii[NCT01449877] | Phase 3 | 141 participants (Actual) | Interventional | 2011-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
10 reviews available for pyrimethamine and Recrudescence
| Article | Year |
|---|---|
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.
Topics: Anemia; Antimalarials; Birth Weight; Child; Child, Preschool; Dietary Supplements; Female; Folic Aci | 2022 |
Antibiotics versus no treatment for toxoplasma retinochoroiditis.
Topics: Administration, Oral; Adult; Anti-Bacterial Agents; Child; Chorioretinitis; Drug Combinations; Human | 2016 |
Toxoplasmic encephalitis relapse rates with pyrimethamine-based therapy: systematic review and meta-analysis.
Topics: AIDS-Related Opportunistic Infections; Anti-HIV Agents; Antiprotozoal Agents; Antiretroviral Therapy | 2017 |
[Acute kidney failure caused by sulfadiazine stones. A complication of the therapy of toxoplasmosis in AIDS].
Topics: Acute Kidney Injury; AIDS-Related Opportunistic Infections; Clindamycin; Drug Therapy, Combination; | 1993 |
Preventing toxoplasmic encephalitis in persons infected with human immunodeficiency virus.
Topics: AIDS-Related Opportunistic Infections; Animals; Anti-Infective Agents; Cats; Dapsone; Drug Therapy, | 1995 |
Pulmonary toxoplasmosis.
Topics: AIDS-Related Opportunistic Infections; Anti-Infective Agents; Biopsy; Humans; Incidence; Lung Diseas | 1997 |
The child with congenital toxoplasmosis.
Topics: Child; Diagnosis, Differential; Eye Diseases; Female; Humans; Infant, Newborn; Infectious Disease Tr | 2000 |
Pneumocystis carinii pneumonia: therapy and prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Anti-Bacterial Agents; Dapsone; Drug Combinations; Drug Therapy, | 1988 |
Prevention of Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; Dapsone; Drug Combinations; Humans; Pentamidine; Pneum | 1988 |
[Importation of malaria into the Federal Republic of Germany including Berlin (West) in the last ten years (1963-1972)].
Topics: Africa; Age Factors; Aircraft; Amodiaquine; Antimalarials; Asia; Berlin; Chloroquine; Disease Outbre | 1974 |
25 trials available for pyrimethamine and Recrudescence
| Article | Year |
|---|---|
Low risk of recurrence following artesunate-Sulphadoxine-pyrimethamine plus primaquine for uncomplicated Plasmodium falciparum and Plasmodium vivax infections in the Republic of the Sudan.
Topics: Adolescent; Adult; Antimalarials; Artemisinins; Child; Child, Preschool; Female; Humans; Infant; Inf | 2018 |
A trial of combination antimalarial therapies in children from Papua New Guinea.
Topics: Antimalarials; Artemether; Artemisinins; Artesunate; Child, Preschool; Chloroquine; Drug Therapy, Co | 2008 |
The effects of a pre-season treatment with effective antimalarials on subsequent malaria morbidity in under five-year-old children living in high and seasonal malaria transmission area of Burkina Faso.
Topics: Age Distribution; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Burkina Fa | 2010 |
Good efficacy of artemether-lumefantrine for uncomplicated falciparum malaria in eastern Sumba, East Nusatenggara, Indonesia.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Drug Combinatio | 2012 |
Chlorproguanil-dapsone versus sulfadoxine-pyrimethamine for sequential episodes of uncomplicated falciparum malaria in Kenya and Malawi: a randomised clinical trial.
Topics: Antimalarials; Cause of Death; Child, Preschool; Dapsone; Developing Countries; Drug Combinations; D | 2002 |
A randomized comparison of chloroquine and chloroquine plus ketotifen in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Administration, Oral; Amodiaquine; Analysis of Variance; Antimalarials; Child; Child, | 2003 |
Comparison of chloroquine, sulfadoxine/pyrimethamine, mefloquine and mefloquine-artesunate for the treatment of falciparum malaria in Kachin State, North Myanmar.
Topics: Adolescent; Adult; Age Distribution; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschoo | 2004 |
A comparison of the efficacy of artesunate plus sulfadoxine-pyrimethamine with that of sulfadoxine-pyrimethamine alone, in the treatment of uncomplicated, Plasmodium falciparum malaria in eastern Sudan.
Topics: Adolescent; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinations; Dru | 2005 |
Prospective randomized trial of trimethoprim/sulfamethoxazole versus pyrimethamine and sulfadiazine in the treatment of ocular toxoplasmosis.
Topics: Adolescent; Adult; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Child; Chorioretinitis; Dru | 2005 |
Efficacy of sulfadoxin pyrimethamine for uncomplicated Plasmodium falciparum malaria in a small sample of Sudanese children.
Topics: Adolescent; Animals; Antimalarials; Artemisinins; Artesunate; Child; Child, Preschool; Drug Combinat | 2004 |
Efficacy of chloroquine and sulfadoxine/pyrimethamine for the treatment of uncomplicated falciparum malaria in Koumantou, Mali.
Topics: Antimalarials; Artemisinins; Chloroquine; Drug Combinations; Female; Humans; Infant; Malaria, Falcip | 2006 |
A fixed-dose 24-hour regimen of artesunate plus sulfamethoxypyrazine-pyrimethamine for the treatment of uncomplicated Plasmodium falciparum malaria in eastern Sudan.
Topics: Adult; Animals; Antimalarials; Artemisinins; Artesunate; Child; Drug Administration Schedule; Drug T | 2006 |
Therapeutic response of multidrug-resistant Plasmodium falciparum and P. vivax to chloroquine and sulfadoxine-pyrimethamine in southern Papua, Indonesia.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Animals; Antimalarials; Child; Child, Preschool; Chloroq | 2007 |
Influence of consecutive-day blood sampling on polymerase chain reaction-adjusted parasitological cure rates in an antimalarial-drug trial conducted in Tanzania.
Topics: Animals; Antigens, Protozoan; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins | 2007 |
Artemether-lumefantrine versus amodiaquine plus sulfadoxine-pyrimethamine for uncomplicated falciparum malaria in Burkina Faso: a randomised non-inferiority trial.
Topics: Amodiaquine; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Burkina Faso; C | 2007 |
Molecular genotyping in a malaria treatment trial in Uganda - unexpected high rate of new infections within 2 weeks after treatment.
Topics: Animals; Antimalarials; Artemisinins; Artesunate; Child; Drug Combinations; Drug Therapy, Combinatio | 2007 |
Effectiveness of amodiaquine as treatment for chloroquine-resistant Plasmodium falciparum infections in Kenya.
Topics: Adolescent; Amodiaquine; Blood; Child; Chloroquine; Drug Combinations; Drug Resistance, Microbial; F | 1984 |
Therapy for ocular toxoplasmosis.
Topics: Adult; Chorioretinitis; Clindamycin; Drug Therapy, Combination; Female; Follow-Up Studies; Glucocort | 1993 |
Atovaquone as long-term suppressive therapy for toxoplasmic encephalitis in patients with AIDS and multiple drug intolerance. Atovaquone Expanded Access Group.
Topics: Acquired Immunodeficiency Syndrome; Adult; Antiprotozoal Agents; Atovaquone; Clindamycin; Encephalit | 1996 |
[Value of clindamycin in the treatment of ocular toxoplasmosis].
Topics: Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Agents; Child; Chorioretinitis; Clindamycin | 1997 |
A randomized comparison of chloroquine, amodiaquine and their combination with pyrimethamine-sulfadoxine in the treatment of acute, uncomplicated, Plasmodium falciparum malaria in children.
Topics: Acute Disease; Amodiaquine; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combi | 2002 |
Pharmacokinetics of sequential and simultaneous treatment with the combination chloroquine and sulfadoxine-pyrimethamine in acute uncomplicated Plasmodium falciparum malaria in the Philippines.
Topics: Acute Disease; Adolescent; Adult; Antimalarials; Area Under Curve; Child; Chloroquine; Drug Administ | 2002 |
Mefloquine-resistant falciparum malaria on the Thai-Burmese border.
Topics: Adolescent; Adult; Animals; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Drug Resist | 1991 |
[Treatment of recurrent congenital ocular toxoplasmosis. Our initial experience with Fansidar].
Topics: Adolescent; Adult; Antimalarials; Child; Clinical Trials as Topic; Drug Combinations; Humans; Pyrime | 1989 |
[Presumed toxoplasmic chorioretinitis: comparative study of treatment with pyrimethamine and sulfadiazine or clindamycin].
Topics: Acute Disease; Adolescent; Adult; Child; Chorioretinitis; Clindamycin; Drug Therapy, Combination; Fe | 1989 |
83 other studies available for pyrimethamine and Recrudescence
| Article | Year |
|---|---|
Development and Optimization of a Selective Whole-Genome Amplification To Study Plasmodium ovale Spp.
Topics: Amino Acids; Endonucleases; Humans; Malaria; Parasitemia; Plasmodium ovale; Pyrimethamine; Recurrenc | 2022 |
Clinical manifestations and visual outcomes associated with ocular toxoplasmosis in a Brazilian population.
Topics: Adolescent; Adult; Age Factors; Aged; Antibodies, Protozoan; Antiprotozoal Agents; Blindness; Brazil | 2021 |
High rates of parasite recrudescence following intermittent preventive treatment with sulphadoxine-pyrimethamine during pregnancy in Benin.
Topics: Adolescent; Adult; Antimalarials; Benin; Dihydropteroate Synthase; Drug Combinations; Female; Haplot | 2013 |
Recurrent seizures during acute acquired toxoplasmosis in an immunocompetent traveller returning from Africa.
Topics: Adolescent; Antibodies, Protozoan; Anticonvulsants; Antiprotozoal Agents; Epilepsy; Ethiopia; Humans | 2016 |
The Impact of Short-Term, Intensive Antifolate Treatment (with Pyrimethamine and Sulfadoxine) and Antibiotics Followed by Long-Term, Secondary Antifolate Prophylaxis on the Rate of Toxoplasmic Retinochoroiditis Recurrence.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Coccidiostats; Drug Administra | 2016 |
Sub-microscopic infections and long-term recrudescence of Plasmodium falciparum in Mozambican pregnant women.
Topics: Adult; Animals; Antigens, Protozoan; Antimalarials; Chloroquine; Drug Combinations; Female; Genotype | 2009 |
Selection of known Plasmodium falciparum resistance-mediating polymorphisms by artemether-lumefantrine and amodiaquine-sulfadoxine-pyrimethamine but not dihydroartemisinin-piperaquine in Burkina Faso.
Topics: Amodiaquine; Antimalarials; Artemether; Artemisinins; Burkina Faso; Drug Combinations; Drug Resistan | 2010 |
Clinical manifestations of new versus recrudescent malaria infections following anti-malarial drug treatment.
Topics: Anemia; Antimalarials; Child; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Fever; | 2012 |
Recurrent isosporiasis over a decade in an immunocompetent host successfully treated with pyrimethamine.
Topics: Albendazole; Animals; Anti-Infective Agents; Antiprotozoal Agents; Chronic Disease; Drug Administrat | 2002 |
Distinguishing recrudescence from reinfection in a longitudinal antimalarial drug efficacy study: comparison of results based on genotyping of msp-1, msp-2, and glurp.
Topics: Amodiaquine; Animals; Antigens, Protozoan; Antimalarials; Artemisinins; Artesunate; Child, Preschool | 2003 |
Asymptomatic, recrudescent, chloroquine-resistant Plasmodium falciparum infections in Nigerian children: clinical and parasitological characteristics and implications for the transmission of drug-resistant parasites.
Topics: Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Combinations; Drug Resistance; Fe | 2003 |
The development of pyrimethamine resistance by Plasmodium falciparum.
Topics: Antimalarials; Communicable Diseases; Humans; Malaria; Malaria, Falciparum; Plasmodium falciparum; P | 1959 |
Recurrence of treated toxoplasmic uveitis.
Topics: Humans; Methylprednisolone; Pyrimethamine; Recurrence; Spiramycin; Sulfamethoxypyridazine; Toxoplasm | 1963 |
Gametocyte sex ratios in children with asymptomatic, recrudescent, pyrimethamine-sulfadoxine-resistant, Plasmodium falciparum malaria.
Topics: Antimalarials; Area Under Curve; Child; Drug Combinations; Drug Resistance; Female; Germ Cells; Huma | 2003 |
Evolution of resistance to sulfadoxine-pyrimethamine in Plasmodium falciparum.
Topics: Animals; Antimalarials; Drug Resistance; Genotype; Half-Life; Models, Biological; Plasmodium falcipa | 2004 |
Recurrent secondary frosted branch angiitis after toxoplasmosis vasculitis.
Topics: Antiprotozoal Agents; Child; Chorioretinitis; Drug Therapy, Combination; Fluorescein Angiography; Gl | 2005 |
Plasmodium falciparum: evaluation of a quantitative nucleic acid sequence-based amplification assay to predict the outcome of sulfadoxine-pyrimethamine treatment of uncomplicated malaria.
Topics: Animals; Antimalarials; Child, Preschool; Dihydropteroate Synthase; Drug Combinations; Drug Resistan | 2005 |
Congenital toxoplasmosis from an HIV-infected woman as a result of reactivation.
Topics: Adult; Animals; Antibodies, Protozoan; Antiprotozoal Agents; Female; Fetal Blood; HIV Infections; Hu | 2006 |
Severe sulfadiazine hypersensitivity in a child with reactivated congenital toxoplasmic chorioretinitis.
Topics: Animals; Antiprotozoal Agents; Child; Chorioretinitis; Drug Hypersensitivity; Drug Therapy, Combinat | 2006 |
Atypical spherical deposition on vitreoretinal interface associated with toxoplasmic chorioretinitis.
Topics: Adult; Antiprotozoal Agents; Betamethasone; Chorioretinitis; Drug Therapy, Combination; Female; Gluc | 2007 |
Roles of specific Plasmodium falciparum mutations in resistance to amodiaquine and sulfadoxine-pyrimethamine in Burkina Faso.
Topics: Amodiaquine; Animals; Antimalarials; Burkina Faso; Dihydropteroate Synthase; Drug Combinations; Drug | 2006 |
HIV immunosuppression and antimalarial efficacy: sulfadoxine-pyrimethamine for the treatment of uncomplicated malaria in HIV-infected adults in Siaya, Kenya.
Topics: Adult; Anemia; Antimalarials; CD4 Lymphocyte Count; Drug Combinations; Female; Fever; HIV Infections | 2006 |
Antimalarial drug combinations in vastly different settings.
Topics: Amodiaquine; Animals; Antimalarials; Artemether, Lumefantrine Drug Combination; Artemisinins; Burkin | 2007 |
Longitudinal study of new eye lesions in treated congenital toxoplasmosis.
Topics: Adolescent; Adult; Antiprotozoal Agents; Child; Child, Preschool; Drug Therapy, Combination; Female; | 2008 |
Comparative drug trial of a sulfadoxine/pyrimethamine and a sulfalene/pyrimethamine combination against Plasmodium falciparum infections in semi-immune populations of Burma.
Topics: Adolescent; Adult; Age Factors; Aged; Anopheles; Blood; Child; Child, Preschool; Drug Administration | 1984 |
[Influence of the treatment on humoral immunity in toxoplasmosis].
Topics: Antibody Formation; Child; Drug Therapy, Combination; Female; Humans; Leucomycins; Male; Pyrimethami | 1984 |
Recurrent toxoplasmic retinochoroiditis after clindamycin: a case report.
Topics: Adult; Chorioretinitis; Clindamycin; Drug Therapy, Combination; Female; Humans; Pyrimethamine; Recur | 1982 |
Late cerebral relapse of congenital toxoplasmosis.
Topics: Child; Chorioretinitis; Drug Therapy, Combination; Encephalitis; Female; Humans; Pyrimethamine; Recu | 1980 |
Impact of transmission intensity and age on Plasmodium falciparum density and associated fever: implications for malaria vaccine trial design.
Topics: Age Factors; Animals; Anopheles; Antimalarials; Child; Child, Preschool; Clinical Trials as Topic; C | 1995 |
Persistent enhancement after treatment for cerebral toxoplasmosis in patients with AIDS: predictive value for subsequent recurrence.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Atrophy; Brain; Brain Abscess; Drug Therapy, Com | 1994 |
Extracerebral toxoplasmosis in patients infected with HIV. A French National Survey.
Topics: Adult; Aged; AIDS-Related Opportunistic Infections; Animals; Clindamycin; Drug Therapy, Combination; | 1994 |
[Recurrence of cerebral toxoplasmosis in 15 AIDS patients].
Topics: Adult; AIDS-Related Opportunistic Infections; Brain; Clindamycin; Drug Therapy, Combination; Female; | 1994 |
Effect of pyrimethamine resistance on sporogony in a Plasmodium berghei/Anopheles stephensi model.
Topics: Animals; Anopheles; Drug Resistance; Female; Insect Vectors; Malaria; Mice; Plasmodium berghei; Pyri | 1994 |
Normal fetal outcome in a pregnancy with central nervous system toxoplasmosis and human immunodeficiency virus infection. A case report.
Topics: Adult; AIDS-Related Opportunistic Infections; Animals; Antibodies, Protozoan; Drug Hypersensitivity; | 1993 |
Efficacy of pyrimethamine/sulfadoxine in the prevention of toxoplasmic encephalitis relapses and Pneumocystis carinii pneumonia in HIV-infected patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Drug Administration Schedule; D | 1993 |
[Cerebral toxoplasmosis in AIDS. 73 cases. Clinical Epidemiology Group on AIDS in Aquitania].
Topics: Acquired Immunodeficiency Syndrome; Adult; AIDS-Related Opportunistic Infections; Clarithromycin; Cl | 1993 |
Quadruple therapy for ocular toxoplasmosis.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Clindamycin; Drug Administration Schedule; Drug Co | 1993 |
Plasmodium falciparum: recrudescence of parasites in culture.
Topics: Animals; Antimalarials; Cells, Cultured; Dose-Response Relationship, Drug; Drug Resistance; Erythroc | 1995 |
Relapse of Toxoplasma encephalitis and susceptibility to pyrimethamine: lack of evidence of treatment-induced resistance.
Topics: Adult; Anti-Infective Agents; Drug Resistance; Encephalitis; Humans; Pyrimethamine; Recurrence; Toxo | 1995 |
Eye manifestations of congenital toxoplasmosis.
Topics: Adolescent; Adult; Anti-Infective Agents; Child; Child, Preschool; Drug Therapy, Combination; Female | 1996 |
Recurrent ocular toxoplasmosis in patients treated with systemic corticosteroids.
Topics: Adolescent; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Antibodies, Protozoan; Antidot | 1996 |
Studies on Plasmodium vivax relapse pattern in Kheda district, Gujarat.
Topics: Adolescent; Adult; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Therapy, Combination; F | 1996 |
A clinical-parasitological monotherapy cure in the treatment of experimental infection by a highly virulent strain of Toxoplasma gondii.
Topics: Animals; Antiprotozoal Agents; Brain; Drug Evaluation, Preclinical; Drug Therapy, Combination; Mice; | 1996 |
Recurrent toxoplasmic retinochoroiditis. Significance of perilesional satellite dark dots seen by indocyanine green angiography.
Topics: Adult; Angiography; Anti-Infective Agents; Chorioretinitis; Coloring Agents; Female; Fluorescein Ang | 1997 |
Indocyanine green angiography features in toxoplasmic retinochoroiditis.
Topics: Acute Disease; Antiprotozoal Agents; Chorioretinitis; Choroid; Drug Therapy, Combination; Female; Fl | 1999 |
[Chloroquine sensitivity of Plasmodium falciparum at the Gamkalley Clinic and the Nigerian armed forces PMI (Niamey, Niger)].
Topics: Adolescent; Adult; Animals; Antimalarials; Child; Child, Preschool; Chloroquine; Drug Resistance; Hu | 1999 |
A toxoplasmic uveitis case of a 60-year-old male in Korea.
Topics: Animals; Antibodies, Protozoan; Antimalarials; Biomarkers; Drug Combinations; Humans; Immune Toleran | 2000 |
Diagnostic value of polymerase chain reaction in blood and aqueous humor in immunocompetent patients with ocular toxoplasmosis.
Topics: Adult; Aged; Aged, 80 and over; Animals; Antiprotozoal Agents; Aqueous Humor; Blotting, Southern; DN | 2000 |
Treatment of dogs infected with Hepatozoon americanum: 53 cases (1989-1998).
Topics: Alkaline Phosphatase; Animals; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Antiprotozoal | 2001 |
[Secondary prevention of opportunistic infections in HIV-infected patients].
Topics: AIDS-Related Opportunistic Infections; Anti-Bacterial Agents; Anti-Infective Agents; Antiprotozoal A | 2001 |
Malaria parasites giving rise to recrudescence in vitro.
Topics: Animals; Antimalarials; Chromatography, High Pressure Liquid; Dose-Response Relationship, Drug; Eryt | 2002 |
Pyrimethamine in prevention of relapses of meningeal leukemia: report of two cases.
Topics: Central Nervous System; Child; Cytarabine; Female; Humans; Injections, Spinal; Leukemia, Lymphoid; M | 1978 |
Failure of chloroquine in human babesiosis (Babesia microti): case report and chemotherapeutic trials in hamsters.
Topics: Animals; Babesiosis; Benzamidines; Chloroquine; Cricetinae; Drug Resistance; Humans; Male; Metronida | 1978 |
[Daraprim in the prevention of recurrences of meningeal involvement in 2 children with acute leukemia followed up for about 8 years].
Topics: Child; Child, Preschool; Female; Follow-Up Studies; Humans; Leukemia, Lymphoid; Male; Meningeal Neop | 1978 |
Chemotherapy of Plasmodium vivax in Saimiri and Aotus models.
Topics: Administration, Oral; Animals; Chloroquine; Disease Models, Animal; Drug Combinations; Drug Evaluati | 1975 |
Adult toxoplasmosis presenting as polymyositis and cerebellar ataxia.
Topics: Antigens; Biopsy; Cerebellar Ataxia; Complement Fixation Tests; Creatine Kinase; Gold Colloid, Radio | 1975 |
A case of recurrent subacute disseminated intravascular coagulation associated with malarial prophylaxis.
Topics: Anemia, Hemolytic; Autopsy; Disseminated Intravascular Coagulation; Heparin; Humans; Malaria; Male; | 1975 |
In vivo response of multi-resistant Plasmodium falciparum infections to mefloquine and its combination with sulfadoxine/pyrimethamine in Cambodia.
Topics: Animals; Cambodia; Drug Combinations; Drug Resistance; Humans; Malaria, Falciparum; Mefloquine; Plas | 1991 |
[Treatment of toxoplasmosis. The treatment of toxoplasmic chorioretinitis].
Topics: Adolescent; Adult; Child; Chorioretinitis; Drug Therapy, Combination; Female; Follow-Up Studies; Hum | 1990 |
[Encephalic toxoplasmosis in patients with the acquired immunodeficiency syndrome. A clinico-radiological study and the therapeutic results in 78 cases].
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Biopsy; Brain; Brain Diseases; Clindamycin; Drug | 1990 |
Toxoplasmic encephalitis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Animals; Antibodies, Protozoan; Brain; Diagnosis, Differe | 1989 |
Pneumocystis carinii pneumonia in Stockholm, Sweden: treatment, outcome, one-year-follow-up and pyrimethamine prophylaxis.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Dapsone; Drug Evaluation; Drug Therapy, Combination | 1989 |
New perspectives in the chemoprophylaxis of toxoplasmosis.
Topics: Chorioretinitis; Drug Combinations; Female; Fetal Diseases; Humans; Immune Tolerance; Infant, Newbor | 1989 |
Experience with pneumocystis carinii pneumonia in patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoscopy; Drug Combinations; Follow-Up Studies; Homos | 1989 |
Fansidar-associated fatal reaction in an HIV-infected man.
Topics: Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; Homosexuality; Humans; Male; Middl | 1988 |
Fansidar and Pneumocystis carinii pneumonia.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Humans; Male; Pneumonia, Pneumocystis; | 1988 |
Isospora belli infection: treatment with pyrimethamine.
Topics: Adult; Coccidiosis; Diarrhea; Drug Combinations; HIV Seropositivity; Humans; Intestinal Diseases, Pa | 1988 |
Leads from the MMWR. Fansidar-associated fatal reaction in an HIV-infected man.
Topics: Drug Combinations; Drug Therapy, Combination; HIV Seropositivity; Homosexuality; Humans; Male; Middl | 1988 |
Clinical evaluation of antimalarial regimens in Japan.
Topics: Animals; Antimalarials; Chloroquine; Drug Therapy, Combination; Humans; Japan; Malaria; Plasmodium f | 1987 |
[Efficacy of specific chemotherapy in the prevention of recurrences of toxoplasmic chorioretinitis during the 4 years following the treatment].
Topics: Adolescent; Adrenal Cortex Hormones; Adult; Child; Chorioretinitis; Drug Therapy, Combination; Femal | 1987 |
Response to treatment in man of multi-drug resistant Plasmodium falciparum from Panama.
Topics: Adult; Amodiaquine; Animals; Anopheles; Antimalarials; Chloroquine; Drug Resistance, Microbial; Drug | 1974 |
Quinine infusion for recrudescences of falciparum malaria in Vietnam: a controlled study.
Topics: Dapsone; Humans; Infusions, Parenteral; Malaria; Plasmodium falciparum; Pyrimethamine; Quinine; Recu | 1972 |
Recrudescent falciparum malaria in Vietnam.
Topics: Adult; Black People; Dapsone; Fever; Follow-Up Studies; Humans; Malaria; Male; Military Medicine; Pl | 1973 |
The evaluation of the presumptive and radical treatments against falciparum malaria in Thailand.
Topics: Adolescent; Adult; Blood; Chloroquine; Drug Evaluation; Female; Humans; Malaria; Male; Plasmodium fa | 1973 |
Recrudescence, poor response or resistance to quinine of falciparum malaria in Thailand.
Topics: Administration, Oral; Adult; Chloroquine; Drug Combinations; Drug Resistance, Microbial; Humans; Inj | 1974 |
Studies on the characterization of plasmodium vivax strains from Central America.
Topics: Animals; Central America; Chloroquine; Haplorhini; Humans; Lincomycin; Malaria; Plasmodium vivax; Pr | 1972 |
[The problems of congenital ocular toxoplasmosis (author's transl)].
Topics: Adolescent; Adult; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Leucomycins; Ma | 1973 |
Acquired decrease in sensitivity to quinine observed during studies with a strain of chloroquine-resistant Plasmodium falciparum.
Topics: Adult; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Male; Plasmodium falciparum; Pyrime | 1967 |
Clinical experience with sulphadiazine and pyrimethamine in the treatment of persons experimentally infected with chloroquine-resistant Plasmodium falciparum.
Topics: Adult; Antimalarials; Body Temperature; Chloroquine; Drug Resistance, Microbial; Humans; Malaria; Ma | 1967 |
The role of drugs in a malaria program.
Topics: Amodiaquine; Antimalarials; Chloroquine; Dose-Response Relationship, Drug; Humans; Malaria; Primaqui | 1972 |
[Experience in the treatment of toxoplasmosis with the "SDDS" preparation].
Topics: Adult; Drug Synergism; Female; Humans; Male; Pyrimethamine; Recurrence; Sulfones; Toxoplasmosis | 1972 |
Treatment of meningeal leukemia with pyrimethamine.
Topics: Adult; Brain Diseases; Folic Acid; Hallucinations; Humans; Leukemia, Myeloid, Acute; Male; Meninges; | 1971 |
Fatal recurrent toxoplasmosis in a patient initially infected via a leukocyte transfusion.
Topics: Autopsy; Child, Preschool; Female; Humans; Leukemia, Lymphoid; Leukocytes; Pyrimethamine; Recurrence | 1971 |