pyrimethamine has been researched along with Porphyrias in 6 studies
Maloprim: contains above 2 cpds
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Administration of the porphyrinogenic agent DDEP to PB-pretreated rats results in acute hepatic heme depletion, which is a characteristic of acute hepatic porphyria." | 3.67 | Drug-induced modulations of hepatic heme metabolism. Neurological consequences. ( Correia, MA; Litman, DA; Lunetta, JM, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cervinka, J | 3 |
| Kaláb, M | 4 |
| Kordac, V | 5 |
| Jirsa, M | 4 |
| Martásek, P | 3 |
| Papezová, R | 1 |
| Kotal, P | 3 |
| Marecek, Z | 2 |
| Soldátová, H | 2 |
| Papezová, P | 1 |
| Correia, MA | 1 |
| Litman, DA | 1 |
| Lunetta, JM | 1 |
| Zoubek, V | 1 |
6 other studies available for pyrimethamine and Porphyrias
| Article | Year |
|---|---|
[Effect of pyrimethamine on clinical and biochemical manifestations of symptomatic liver porphyria].
Topics: Adult; Female; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Pyrimethamine | 1983 |
[Experimental study of the action of antimalarial agents with respect to therapy in porphyria. Combined effect of chloroquine and pyrimethamine].
Topics: Chloroquine; Humans; Porphyrias; Porphyrins; Pyrimethamine; Saccharomyces cerevisiae | 1989 |
[2 years' experience with combined therapy of symptomatic liver porphyria using pyrimethamine and chloroquine].
Topics: Adult; Chloroquine; Drug Therapy, Combination; Female; Humans; Liver Diseases; Male; Middle Aged; Po | 1988 |
Drug-induced modulations of hepatic heme metabolism. Neurological consequences.
Topics: Animals; Brain; Gastric Emptying; Gluconeogenesis; Heme; Intestine, Small; Liver; Liver Diseases; Mo | 1987 |
[Experience with the therapy of symptomatic liver porphyria using a combination of antimalarial agents--chloroquine with pyrimethamine].
Topics: Adult; Aged; Chloroquine; Drug Therapy, Combination; Humans; Liver Diseases; Male; Middle Aged; Porp | 1987 |
[2 years' experience with the treatment of symptomatic liver porphyria with pyrimethamine].
Topics: Female; Humans; Liver Diseases; Male; Middle Aged; Porphyrias; Pyrimethamine | 1985 |