pyrimethamine has been researched along with Pneumocystis Infections in 9 studies
Maloprim: contains above 2 cpds
Pneumocystis Infections: Infections with species in the genus PNEUMOCYSTIS, a fungus causing interstitial plasma cell pneumonia (PNEUMONIA, PNEUMOCYSTIS) and other infections in humans and other MAMMALS. Immunocompromised patients, especially those with AIDS, are particularly susceptible to these infections. Extrapulmonary sites are rare but seen occasionally.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Extending these experiments, we have now shown that roxithromycin at doses of 400 or 200 mg/kg/day combined with dapsone at doses of 5, 25 or 50 mg/kg/day completely prevented the development of T." | 1.30 | Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model. ( Brun-Pascaud, M; Chau, F; Derouin, F; Girard, PM, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (66.67) | 18.2507 |
| 2000's | 3 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, L | 1 |
| Jia, Q | 1 |
| Kovacs, JA | 1 |
| Nahimana, A | 2 |
| Rabodonirina, M | 2 |
| Zanetti, G | 1 |
| Meneau, I | 1 |
| Francioli, P | 2 |
| Bille, J | 2 |
| Hauser, PM | 2 |
| Mehlhorn, H | 1 |
| Dankert, W | 1 |
| Hartman, PG | 1 |
| Then, RL | 1 |
| Hughes, WT | 1 |
| Killmar, JT | 1 |
| Oz, HS | 1 |
| Brun-Pascaud, M | 3 |
| Chau, F | 3 |
| Simonpoli, AM | 1 |
| Girard, PM | 3 |
| Derouin, F | 3 |
| Pocidalo, JJ | 1 |
| Podzamczer, D | 1 |
| Martos, A | 1 |
| Ferrer, I | 1 |
| Santin, M | 1 |
| Gudiol, F | 1 |
| Garry, L | 1 |
| Jacobus, D | 1 |
9 other studies available for pyrimethamine and Pneumocystis Infections
| Article | Year |
|---|---|
Development of a yeast assay for rapid screening of inhibitors of human-derived Pneumocystis carinii dihydrofolate reductase.
Topics: Animals; Drug Evaluation, Preclinical; Folic Acid Antagonists; Humans; Pneumocystis; Pneumocystis In | 2002 |
Association between a specific Pneumocystis jiroveci dihydropteroate synthase mutation and failure of pyrimethamine/sulfadoxine prophylaxis in human immunodeficiency virus-positive and -negative patients.
Topics: Adolescent; Adult; Aged; Alleles; Anti-Bacterial Agents; Antibiotic Prophylaxis; Bronchoalveolar Lav | 2003 |
Mutations of Pneumocystis jirovecii dihydrofolate reductase associated with failure of prophylaxis.
Topics: Adult; Amino Acid Sequence; Anti-Bacterial Agents; Bronchoalveolar Lavage Fluid; Cloning, Molecular; | 2004 |
A pilot study on the efficacy of epiroprim against developmental stages of Toxoplasma gondii and Pneumocystis carinii in animal models.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Drug Therapy, Combination; Female; F | 1995 |
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Tria | 1994 |
Experimental evaluation of combined prophylaxis against murine pneumocystosis and toxoplasmosis.
Topics: Animals; Antifungal Agents; Antiprotozoal Agents; Atovaquone; Brain; Dapsone; Drug Therapy, Combinat | 1994 |
Hepatic and pulmonary pneumocystosis during primary prophylaxis for Pneumocystis carinii pneumonia with dapsone/pyrimethamine.
Topics: Adult; AIDS-Related Opportunistic Infections; Dapsone; Drug Therapy, Combination; Humans; Liver Dise | 1993 |
Combination of PS-15, epiroprim, or pyrimethamine with dapsone in prophylaxis of Toxoplasma gondii and Pneumocystis carinii dual infection in a rat model.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Dapsone; Drug Therapy, Combination; Folic Acid | 1996 |
Experimental evaluation of roxithromycin combined with dapsone or sulphamethoxazole on Pneumocystis carinii and Toxoplasma gondii dual infections in a rat model.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Disease Models, Animal; Dose-Respons | 1998 |