pyrimethamine has been researched along with Opportunistic Infections in 25 studies
Maloprim: contains above 2 cpds
Opportunistic Infections: An infection caused by an organism which becomes pathogenic under certain conditions, e.g., during immunosuppression.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The relative risks of non-specific upper respiratory tract infections were studied in two well matched groups of military recruits to see whether dapsone-pyrimethamine (Maloprim) given as antimalarial prophylaxis was associated with immunosuppression." | 7.67 | Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria. ( Lau, EY; Lee, PS, 1988) |
| "The relative risks of non-specific upper respiratory tract infections were studied in two well matched groups of military recruits to see whether dapsone-pyrimethamine (Maloprim) given as antimalarial prophylaxis was associated with immunosuppression." | 3.67 | Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria. ( Lau, EY; Lee, PS, 1988) |
| " Dosage must be adjusted to the results of blood counts." | 2.38 | [Usefulness of folinic acid in cytopenia induced by antiparasitic drugs in AIDS patients]. ( Leport, C; Niyongabo, T; Vildé, JL, 1991) |
| "In patients with AIDS, toxoplasmosis is the most common cause of CNS mass lesions." | 2.38 | Toxoplasmosis in AIDS patients. ( Tuazon, CU, 1989) |
| "The literature on toxoplasmosis in the acquired immune deficiency syndrome is reviewed with reference to more than 140 cases from various centres." | 2.37 | Toxoplasmosis and the acquired immune deficiency syndrome. ( Holliman, RE, 1988) |
| "Patients with cerebral toxoplasmosis have a low risk for subsequently developing P." | 1.28 | Treatment for cerebral toxoplasmosis protects against Pneumocystis carinii pneumonia in patients with AIDS. The Swiss HIV Cohort Study. ( Chave, JP; Flepp, M; Gabriel, V; Heald, A; Hirschel, B; Malinverni, R; Renold, C; Rüttimann, S; Sugar, A, 1991) |
| "No relapse was observed in those receiving P/S, but 40% of those treated with P/C relapsed." | 1.28 | [Encephalic toxoplasmosis in patients with the acquired immunodeficiency syndrome. A clinico-radiological study and the therapeutic results in 78 cases]. ( Alvarez, R; Gatell, JM; González-Clemente, JM; Graus, F; Guelar, A; Jiménez de Anta, MT; Mallolas, J; Mercader, JM; Miró, JM; Pedrol, E, 1990) |
| "Pulmonary toxoplasmosis in AIDS is rare." | 1.28 | [Pulmonary toxoplasmosis in AIDS. Report of 3 cases]. ( Bouslama, K; Cabane, J; Gonzalez Canali, G; Imbert, JC; Knani, L; Lebas, J; Varette, C, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (24.00) | 18.7374 |
| 1990's | 14 (56.00) | 18.2507 |
| 2000's | 3 (12.00) | 29.6817 |
| 2010's | 2 (8.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Queener, SF | 2 |
| Piper, JR | 1 |
| Johnson, CA | 1 |
| Krauth, CA | 1 |
| Carter, RL | 1 |
| Hosmer, CA | 1 |
| Borotz, SE | 1 |
| Pfefferkorn, ER | 1 |
| Lee, PS | 1 |
| Lau, EY | 1 |
| Le Clech, L | 1 |
| Hutin, P | 1 |
| Le Gal, S | 1 |
| Guillerm, G | 1 |
| Miyagi, T | 1 |
| Itonaga, H | 1 |
| Aosai, F | 1 |
| Taguchi, J | 1 |
| Norose, K | 1 |
| Mochizuki, K | 1 |
| Fujii, H | 1 |
| Furumoto, A | 1 |
| Ohama, M | 1 |
| Karimata, K | 1 |
| Yamanoha, A | 1 |
| Taniguchi, H | 1 |
| Sato, S | 1 |
| Taira, N | 1 |
| Moriuchi, Y | 1 |
| Fukushima, T | 1 |
| Masuzaki, H | 1 |
| Miyazaki, Y | 1 |
| Seta, N | 1 |
| Shimizu, T | 1 |
| Nawata, M | 1 |
| Wada, R | 1 |
| Mori, K | 1 |
| Sekigawa, I | 1 |
| Iida, N | 1 |
| Maeda, M | 1 |
| Hashimoto, H | 1 |
| Holtkamp, M | 1 |
| Okuducu, AF | 1 |
| Klingebiel, R | 1 |
| Ploner, CJ | 1 |
| Baran, DA | 1 |
| Alwarshetty, MM | 1 |
| Alvi, S | 1 |
| Arroyo, LH | 1 |
| Lubitz, S | 1 |
| Pinney, S | 1 |
| Gass, AL | 1 |
| Zucker, MJ | 1 |
| Peacock, JE | 1 |
| Greven, CM | 1 |
| Cruz, JM | 1 |
| Hurd, DD | 1 |
| Hardy, WD | 2 |
| de Gans, J | 1 |
| Portegies, P | 1 |
| Reiss, P | 1 |
| Troost, D | 1 |
| van Gool, T | 1 |
| Lange, JM | 1 |
| Niyongabo, T | 2 |
| Leport, C | 3 |
| Vildé, JL | 2 |
| Heald, A | 1 |
| Flepp, M | 1 |
| Chave, JP | 1 |
| Malinverni, R | 1 |
| Rüttimann, S | 1 |
| Gabriel, V | 1 |
| Renold, C | 1 |
| Sugar, A | 1 |
| Hirschel, B | 1 |
| Katlama, C | 1 |
| Tournerie, C | 1 |
| Raguin, G | 1 |
| Fernandez-Martin, J | 1 |
| González-Clemente, JM | 1 |
| Miró, JM | 1 |
| Pedrol, E | 1 |
| Alvarez, R | 1 |
| Gatell, JM | 1 |
| Mallolas, J | 1 |
| Graus, F | 1 |
| Mercader, JM | 1 |
| Guelar, A | 1 |
| Jiménez de Anta, MT | 1 |
| Lucey, DR | 1 |
| Lucey, CR | 1 |
| Knani, L | 1 |
| Bouslama, K | 1 |
| Varette, C | 1 |
| Gonzalez Canali, G | 1 |
| Cabane, J | 1 |
| Lebas, J | 1 |
| Imbert, JC | 1 |
| Chakroun, M | 1 |
| Meyohas, MC | 1 |
| Pelosse, B | 1 |
| Zazoun, L | 1 |
| Vacherot, B | 1 |
| Derouin, F | 1 |
| Luft, BJ | 1 |
| Hafner, R | 1 |
| Tuazon, CU | 1 |
| Bonaventura, I | 1 |
| Romero, F | 1 |
| Ortega, A | 1 |
| Navarro, C | 1 |
| Juste, C | 1 |
| Codina Puiggrós, A | 1 |
| Wilfert, H | 1 |
| Tappeiner, G | 1 |
| Holliman, RE | 1 |
8 reviews available for pyrimethamine and Opportunistic Infections
| Article | Year |
|---|---|
New drug developments for opportunistic infections in immunosuppressed patients: Pneumocystis carinii.
Topics: Animals; Drug Design; Humans; Immunosuppression Therapy; Molecular Structure; Opportunistic Infectio | 1995 |
Successful treatment of toxoplasmic encephalitis diagnosed early by polymerase chain reaction after allogeneic hematopoietic stem cell transplantation: two case reports and review of the literature.
Topics: Adult; Antiprotozoal Agents; Drug Therapy, Combination; Early Diagnosis; Hematopoietic Stem Cell Tra | 2015 |
Reactivation toxoplasmic retinochoroiditis in patients undergoing bone marrow transplantation: is there a role for chemoprophylaxis?
Topics: Animals; Antibodies, Protozoan; Antineoplastic Combined Chemotherapy Protocols; Antiprotozoal Agents | 1995 |
Prophylaxis of AIDS-related opportunistic infections (OIs). Current status and future strategies.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; Animals; Cryptococcosis; Cytomegalovirus Infections; D | 1991 |
[Usefulness of folinic acid in cytopenia induced by antiparasitic drugs in AIDS patients].
Topics: Acquired Immunodeficiency Syndrome; Drug Therapy, Combination; Folic Acid; Hematologic Diseases; Hum | 1991 |
Prophylaxis of AIDS-related opportunistic infections (OIs).
Topics: Acquired Immunodeficiency Syndrome; Cryptococcosis; Cytomegalovirus Infections; Dapsone; Drug Combin | 1989 |
Toxoplasmosis in AIDS patients.
Topics: Acquired Immunodeficiency Syndrome; Animals; Drug Therapy, Combination; Humans; Mice; Opportunistic | 1989 |
Toxoplasmosis and the acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Africa; Animals; Antibodies, Protozoan; Drug Combinations; Human | 1988 |
2 trials available for pyrimethamine and Opportunistic Infections
| Article | Year |
|---|---|
Prophylaxis of AIDS-related opportunistic infections (OIs). Current status and future strategies.
Topics: Acquired Immunodeficiency Syndrome; Aerosols; Animals; Cryptococcosis; Cytomegalovirus Infections; D | 1991 |
Evaluation of the efficacy and safety of clindamycin plus pyrimethamine for induction and maintenance therapy of toxoplasmic encephalitis in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Drug Therapy, Combination; Encephalitis; Humans; Op | 1991 |
16 other studies available for pyrimethamine and Opportunistic Infections
| Article | Year |
|---|---|
Lipophilic antifolates as agents against opportunistic infections. 1. Agents superior to trimetrexate and piritrexim against Toxoplasma gondii and Pneumocystis carinii in in vitro evaluations.
Topics: Animals; Anti-Infective Agents; Folic Acid Antagonists; Opportunistic Infections; Pneumocystis; Pneu | 1996 |
Risk of acute non-specific upper respiratory tract infections in healthy men taking dapsone-pyrimethamine for prophylaxis against malaria.
Topics: Acute Disease; Adolescent; Antimalarials; Dapsone; Drug Combinations; Humans; Immunosuppression Ther | 1988 |
Skin nodules in a patient with acute lymphoblastic leukaemia.
Topics: Adolescent; Amphotericin B; Cord Blood Stem Cell Transplantation; Dermatomycoses; Diagnosis, Differe | 2014 |
A possible novel mechanism of opportunistic infection in systemic lupus erythematosus, based on a case of toxoplasmic encephalopathy.
Topics: Adult; Animals; Anti-Infective Agents; Antibodies, Protozoan; Cerebral Cortex; Drug Combinations; Fe | 2002 |
Cerebral toxoplasmosis in a patient with common variable immunodeficiency.
Topics: Anemia, Hemolytic, Autoimmune; Antibodies, Protozoan; Antiprotozoal Agents; Biopsy; Brain; Central N | 2004 |
Is toxoplasmosis prophylaxis necessary in cardiac transplantation? Long-term follow-up at two transplant centers.
Topics: Adult; Anti-Infective Agents; Antiprotozoal Agents; Female; Follow-Up Studies; Graft Rejection; Hear | 2006 |
Pyrimethamine alone as maintenance therapy for central nervous system toxoplasmosis in 38 patients with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Therapy, Combination; Female; Humans; Male; Opportun | 1992 |
Treatment for cerebral toxoplasmosis protects against Pneumocystis carinii pneumonia in patients with AIDS. The Swiss HIV Cohort Study.
Topics: Acquired Immunodeficiency Syndrome; Adult; Aged; Clindamycin; Cohort Studies; Drug Therapy, Combinat | 1991 |
Long-term follow-up of patients with AIDS on maintenance therapy for toxoplasmosis.
Topics: Acquired Immunodeficiency Syndrome; Clindamycin; Drug Therapy, Combination; Encephalitis; Follow-Up | 1991 |
[Encephalic toxoplasmosis in patients with the acquired immunodeficiency syndrome. A clinico-radiological study and the therapeutic results in 78 cases].
Topics: Acquired Immunodeficiency Syndrome; Acute Disease; Biopsy; Brain; Brain Diseases; Clindamycin; Drug | 1990 |
Infectious disease emergencies in persons with HIV/AIDS: an update.
Topics: Acquired Immunodeficiency Syndrome; Amphotericin B; Clindamycin; Communicable Diseases; Fluconazole; | 1990 |
[Pulmonary toxoplasmosis in AIDS. Report of 3 cases].
Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoalveolar Lavage Fluid; Drug Therapy, Combination; | 1990 |
[Ocular toxoplasmosis in AIDS].
Topics: Acquired Immunodeficiency Syndrome; Adult; Brain Diseases; Humans; Male; Middle Aged; Opportunistic | 1990 |
Toxoplasmic encephalitis.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Encephalitis; Humans; Opportunistic Infection | 1990 |
[Cerebral toxoplasmosis in the acquired immunodeficiency syndrome. Study of the clinical, radiological, and pathological findings in 10 cases].
Topics: Acquired Immunodeficiency Syndrome; Brain Abscess; Brain Diseases; Humans; Opportunistic Infections; | 1988 |
[Toxoplasma infection in dermatomyositis].
Topics: Adult; Dermatomyositis; Diagnosis, Differential; Drug Therapy, Combination; Erythema Multiforme; Fem | 1988 |