Page last updated: 2024-11-03

pyrimethamine and Neutropenia

pyrimethamine has been researched along with Neutropenia in 6 studies

Maloprim: contains above 2 cpds

Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.

Research Excerpts

ExcerptRelevanceReference
"Amodiaquine+SP is not well tolerated and a substantial proportion of patients experienced pruritus and fatigue, thus decreasing their compliance and compromising the first line treatment implementation at national level."9.12Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults. ( D'Alessandro, U; Fanello, CI; Karema, C; Rwagacondo, CE; van Doren, W, 2006)
"Amodiaquine+SP is not well tolerated and a substantial proportion of patients experienced pruritus and fatigue, thus decreasing their compliance and compromising the first line treatment implementation at national level."5.12Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults. ( D'Alessandro, U; Fanello, CI; Karema, C; Rwagacondo, CE; van Doren, W, 2006)
" In most cases, it was not severe and reversed after increase in folinic acid dosage (25."1.46High Frequency of Bone Marrow Depression During Congenital Toxoplasmosis Therapy in a Cohort of Children Identified by Neonatal Screening in Minas Gerais, Brazil. ( Carellos, EVM; de Andrade, GMQ; de Andrade, JQ; Figueiredo, RM; Januário, JN; Romanelli, RMC; Tibúrcio, JD; Vasconcelos-Santos, DV, 2017)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (33.33)18.2507
2000's3 (50.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carellos, EVM1
de Andrade, JQ1
Romanelli, RMC1
Tibúrcio, JD1
Januário, JN1
Vasconcelos-Santos, DV1
Figueiredo, RM1
de Andrade, GMQ1
Peters, E1
Seaton, A1
Chemla, C1
Villena, I1
Trenque, T1
Pinon, JM1
Fanello, CI1
Karema, C1
van Doren, W1
Rwagacondo, CE1
D'Alessandro, U1
McAuley, J1
Boyer, KM1
Patel, D1
Mets, M1
Swisher, C1
Roizen, N1
Wolters, C1
Stein, L1
Stein, M1
Schey, W1
Moreno García, M1
Fernández González, F1
Fernández Rodríguez, E1
Portús de Marco, MV1

Trials

2 trials available for pyrimethamine and Neutropenia

ArticleYear
Tolerability of amodiaquine and sulphadoxine-pyrimethamine, alone or in combination for the treatment of uncomplicated Plasmodium falciparum malaria in Rwandan adults.
    Tropical medicine & international health : TM & IH, 2006, Volume: 11, Issue:5

    Topics: Adult; Amodiaquine; Antimalarials; Blood Cell Count; Double-Blind Method; Drug Combinations; Drug Th

2006
Early and longitudinal evaluations of treated infants and children and untreated historical patients with congenital toxoplasmosis: the Chicago Collaborative Treatment Trial.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 1994, Volume: 18, Issue:1

    Topics: Animals; Calcinosis; Chemistry, Pharmaceutical; Child; Child, Preschool; Drug Administration Schedul

1994

Other Studies

4 other studies available for pyrimethamine and Neutropenia

ArticleYear
High Frequency of Bone Marrow Depression During Congenital Toxoplasmosis Therapy in a Cohort of Children Identified by Neonatal Screening in Minas Gerais, Brazil.
    The Pediatric infectious disease journal, 2017, Volume: 36, Issue:12

    Topics: Antiprotozoal Agents; Bone Marrow; Brazil; Child, Preschool; Female; Humans; Infant; Infant, Newborn

2017
Bio-hazards and drug reactions: a cautionary tale.
    Scandinavian journal of infectious diseases, 2005, Volume: 37, Issue:4

    Topics: Adult; Anti-Bacterial Agents; Drug Combinations; Humans; Leucovorin; Male; Meningitis, Listeria; Neu

2005
[Prenatal treatment of congenital toxoplasmosis].
    Presse medicale (Paris, France : 1983), 2005, Dec-17, Volume: 34, Issue:22 Pt 1

    Topics: Antimalarials; Drug Combinations; Female; Follow-Up Studies; Humans; Leucovorin; Neutropenia; Pregna

2005
[Granulocyte colony-stimulating factor in the treatment of neutropenia associated with HIV infection].
    Medicina clinica, 1996, Jul-06, Volume: 107, Issue:6

    Topics: Acquired Immunodeficiency Syndrome; Acyclovir; Adult; Anti-Infective Agents; Antiviral Agents; Cefta

1996